Detailed information for compound 415197

Basic information

Technical information
  • TDR Targets ID: 415197
  • Name: (2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydr oxy-2,3-dihydrochromen-4-one
  • MW: 304.252 | Formula: C15H12O7
  • H donors: 5 H acceptors: 6 LogP: 1.48 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cc2O[C@H](c3ccc(c(c3)O)O)[C@@H](C(=O)c2c(c1)O)O
  • InChi: 1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15-/m1/s1
  • InChiKey: CXQWRCVTCMQVQX-HUUCEWRRSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-4-one
  • (2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-4-one
  • Quercetin
  • taxifolin
  • (2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one
  • (2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-chromanone
  • ZINC00105086

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens glucosidase, alpha Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum ko:K01187 alpha-glucosidase [EC3.2.1.20], putative Get druggable targets OG5_127055 All targets in OG5_127055
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum Lysosomal alpha-glucosidase precursor, putative Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) glycosyl hydrolase family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Get druggable targets OG5_127055 All targets in OG5_127055
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Glycosyl hydrolases family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Giardia lamblia U5 small nuclear ribonucleoprotein 200 kDa helicase, putative RecQ helicase-like 649 aa 521 aa 19.8 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis DNA helicase recq, putative 0.005 0.0036 0.0136
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus granulosus rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0048 0.0162
Entamoeba histolytica hypothetical protein 0.0026 0.0011 0.0513
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0023 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0023 0.0038
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0056 0.0042 0.0141
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0242 0.0232 0.0915
Echinococcus granulosus orexin receptor type 2 0.0198 0.0187 0.0312
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0111 0.0098 0.0332
Echinococcus multilocularis MAGUK p55 subfamily 0.0016 0.0001 0.0002
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0049 0.0035 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Brugia malayi MH1 domain containing protein 0.0016 0.0001 0.0005
Onchocerca volvulus 0.0287 0.0279 0.0943
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0014 0.0023
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0288 0.0279 0.0464
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0008 0.0392
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0023 0.0023
Plasmodium falciparum plasmepsin IX 0.0096 0.0083 0.0282
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.014 0.0129 0.0438
Schistosoma mansoni smad1 5 8 and 0.0016 0.0001 0.0001
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0016 0.0001 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0054 0.0041 0.0135
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0107 0.0095 0.0157
Echinococcus multilocularis expressed protein 0.004 0.0026 0.0043
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0107 0.0095 0.0321
Loa Loa (eye worm) hypothetical protein 0.0491 0.0488 0.1655
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0049 0.0035 0.0116
Onchocerca volvulus 0.0081 0.0068 0.0226
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0014 0.0045
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0049 0.0035 0.0134
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Treponema pallidum sodium- and chloride- dependent transporter 0.2894 0.2951 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0064 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.011 0.0098 0.0331
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0049 0.0035 0.0134
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0004 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0198 0.0187 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0021 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0111 0.0098 0.0332
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1655
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0098 0.0383
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0023 0.0086
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0048 0.016
Brugia malayi Hemopexin family protein 0.0104 0.0092 0.0311
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0023 0.0075
Brugia malayi Matrixin family protein 0.0074 0.006 0.0204
Onchocerca volvulus 0.0491 0.0488 0.1651
Trichomonas vaginalis glycogen phosphorylase, putative 0.013 0.0118 0.0464
Echinococcus granulosus survival motor neuron protein 1 0.0479 0.0476 0.0791
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0185 0.0174 0.0685
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0056 0.0043 0.0163
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0185 0.0174 0.0685
Echinococcus granulosus hypothetical protein 0.0016 0.0001 0.0002
Echinococcus multilocularis oxidoreductase 0.0016 0.0001 0.0002
Loa Loa (eye worm) beta-lactamase 0.0037 0.0023 0.0078
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.006 0.0046 0.0178
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0037 0.0023 0.0038
Entamoeba histolytica thioredoxin reductase, putative 0.0049 0.0035 0.176
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1675
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Brugia malayi DNA repair protein RAD51 homolog 1 0.0024 0.001 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0064 0.005 0.005
Loa Loa (eye worm) aspartyl protease 6 0.0096 0.0083 0.0282
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0048 0.0034 0.0111
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0035 0.002 0.0065
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0377 0.0371 0.1466
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0014 0.0046
Schistosoma mansoni hypothetical protein 0.0233 0.0224 0.0224
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0145 0.0134 0.0453
Leishmania major hypothetical protein, conserved 0.0049 0.0035 0.0116
Loa Loa (eye worm) IMP dehydrogenase 1 0.0107 0.0095 0.0321
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0021 0.0067
Onchocerca volvulus Matrilysin homolog 0.0163 0.0152 0.0512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0009
Leishmania major DNA polymerase eta, putative 0.0051 0.0037 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Schistosoma mansoni rab6-interacting 0.0048 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Plasmodium falciparum thioredoxin reductase 0.0185 0.0174 0.0595
Schistosoma mansoni biogenic amine receptor 0.0198 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0108
Mycobacterium tuberculosis Conserved hypothetical protein 0.0064 0.005 0.0195
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0026 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.1097 0.1109 0.1843
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0049 0.0035 0.0134
Mycobacterium leprae Probable Holliday junction DNA helicase component RuvA 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0479 0.0476 0.1612
Entamoeba histolytica glycogenphosphorylase, putative 0.0056 0.0043 0.215
Echinococcus multilocularis neuropeptide s receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.0062
Onchocerca volvulus 0.0114 0.0101 0.0339
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.009 0.0077 0.0299
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0014 0.0014
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0119 0.0119
Leishmania major hypothetical protein, conserved 0.0019 0.0004 0.001
Echinococcus granulosus lamin 0.0081 0.0068 0.0113
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0048 0.016
Schistosoma mansoni memapsin-2 (A01 family) 0.1311 0.1329 0.1329
Trypanosoma brucei DNA polymerase IV, putative 0.0088 0.0075 0.0254
Mycobacterium ulcerans NADH dehydrogenase 0.0049 0.0035 0.0134
Brugia malayi CHD4 protein 0.0017 0.0002 0.0008
Trypanosoma brucei GMP reductase 0.0107 0.0095 0.0321
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0491 0.0488 0.0811
Plasmodium falciparum plasmepsin V 0.0096 0.0083 0.0282
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0049 0.0035 0.0119
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0198 0.0187 0.0631
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0033 0.0126
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0049 0.0035 0.0117
Schistosoma mansoni hypothetical protein 0.0104 0.0092 0.0092
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0049 0.0035 0.0134
Giardia lamblia DINP protein human, muc B family 0.0072 0.0059 0.3316
Onchocerca volvulus 0.0037 0.0023 0.0074
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0009 0.0032
Mycobacterium ulcerans hydrolase 0.009 0.0077 0.0299
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.003 0.0112
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0056 0.0042 0.0141
Treponema pallidum oxidoreductase 0.0049 0.0035 0.0113
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0056 0.0042 0.0162
Brugia malayi Guanylate kinase family protein 0.0016 0.0001 0.0004
Mycobacterium tuberculosis Conserved protein 0.0037 0.0023 0.0086
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0056 0.0042 0.0162
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0056 0.0042 0.0162
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0056 0.0042 0.0162
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0014 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0051 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0014
Giardia lamblia GTOR 0.0019 0.0004 0.0155
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0035 0.002 0.0075
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0072 0.0059 0.0197
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0047 0.0033 0.0127
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0004 0.0004
Leishmania major DNA polymerase kappa, putative 0.002 0.0005 0.0013
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0056 0.0042 0.0162
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0056 0.0042 0.0162
Echinococcus multilocularis glycogen phosphorylase 0.013 0.0118 0.0197
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0035 0.0116
Giardia lamblia Glycogen phosphorylase 0.013 0.0118 0.6772
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0019 0.007
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0133 0.0121 0.0202
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0185 0.0174 0.0595
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0021 0.1034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0056 0.0042 0.0162
Schistosoma mansoni coup transcription factor 0.0028 0.0014 0.0014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0222 0.0212 0.0718
Plasmodium falciparum thioredoxin reductase 0.0533 0.0531 0.1824
Schistosoma mansoni hypothetical protein 0.0107 0.0095 0.0095
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0185 0.0174 0.0174
Schistosoma mansoni hypothetical protein 0.011 0.0098 0.0098
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0004 0.0007
Brugia malayi sulfakinin receptor protein 0.0198 0.0187 0.0635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0132 0.012 0.02
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0081 0.0067 0.0112
Plasmodium vivax thioredoxin reductase, putative 0.0533 0.0531 0.1824
Plasmodium vivax DNA repair protein REV1, putative 0.002 0.0005 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0198 0.0187 0.0187
Schistosoma mansoni netrin receptor unc5 0.0046 0.0032 0.0032
Plasmodium vivax ferrodoxin reductase, putative 0.0049 0.0035 0.0116
Schistosoma mansoni DNA polymerase IV / kappa 0.002 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi transcription elongation factor NusA 0.0017 0.0002 0.0002
Brugia malayi Peripheral plasma membrane protein CASK 0.0021 0.0006 0.0022
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0056 0.0042 0.0162
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0037 0.0124
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0002 0.0003
Brugia malayi hypothetical protein 0.0491 0.0488 0.1655
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus twitchin 0.0038 0.0024 0.0039
Schistosoma mansoni biogenic amine (5HT) receptor 0.0198 0.0187 0.0187
Loa Loa (eye worm) proteasome subunit beta type 1 0.0054 0.0041 0.0137
Echinococcus multilocularis dna polymerase kappa 0.0096 0.0083 0.0139
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0035 0.002 0.0062
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.0119 0.0467
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0029 0.0099
Schistosoma mansoni microtubule-associated protein tau 0.2066 0.2102 0.2102
Onchocerca volvulus 0.2894 0.2951 1
Echinococcus multilocularis nmda type glutamate receptor 0.0048 0.0034 0.0056
Echinococcus multilocularis neuroglian 0.0037 0.0023 0.0039
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0098 0.0163
Echinococcus granulosus tachykinin peptides receptor 99D 0.0198 0.0187 0.0312
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Echinococcus granulosus g protein coupled receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0049 0.0035 0.0119
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0491 0.0488 0.0811
Plasmodium falciparum amino acid transporter, putative 0.0491 0.0488 0.1675
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0014 0.0014
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0203 0.0193 0.0193
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0021 0.0067
Trypanosoma cruzi ribonucleoside-diphosphate reductase small chain, putative 0.014 0.0129 0.0438
Loa Loa (eye worm) hypothetical protein 0.008 0.0066 0.0225
Echinococcus multilocularis Immunoglobulin 0.0037 0.0023 0.0038
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0004 0.001
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0001 0.0002
Brugia malayi hypothetical protein 0.011 0.0098 0.0331
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Toxoplasma gondii ImpB/MucB/SamB family protein 0.002 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.0079
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0049 0.0035 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Brugia malayi glutathione reductase 0.0533 0.0531 0.1801
Onchocerca volvulus 0.0491 0.0488 0.1651
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0013 0.0045
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1655
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0185 0.0174 0.0595
Brugia malayi Cell death protein 3 precursor 0.0145 0.0134 0.0453
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0009 0.0028
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0133 0.0121 0.0202
Loa Loa (eye worm) serotonin transporter b 0.2894 0.2951 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0049 0.0035 0.0134
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit beta 0.014 0.0129 0.0504
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0049 0.0035 0.176
Brugia malayi Integrin beta pat-3 precursor 0.032 0.0312 0.1058
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0069 0.0056 0.0093
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.003 0.0097
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0095 0.0158
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0002 0.0008
Brugia malayi Protein kinase domain containing protein 0.0058 0.0044 0.0148
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0049 0.0035 0.0116
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0049 0.0035 0.0058
Leishmania major ribonucleoside-diphosphate reductase small chain, putative 0.014 0.0129 0.0438
Brugia malayi putative neuropeptide receptor 0.0198 0.0187 0.0635
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0081 0.0067 0.0228
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0185 0.0174 0.0595
Toxoplasma gondii ribonucleoside-diphosphate reductase small subunit 0.014 0.0129 0.0438
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0014 0.0046
Brugia malayi Bloom's syndrome protein homolog 0.005 0.0036 0.0121
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0054 0.0041 0.0041
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0083 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0071 0.0241
Schistosoma mansoni sodium/chloride dependent transporter 0.2894 0.2951 0.2951
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0022 0.0074
Schistosoma mansoni biogenic amine receptor 0.0198 0.0187 0.0187
Brugia malayi Uncoordinated protein 44 0.0046 0.0032 0.0108
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0359 0.1229
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0005 0.0013
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0047 0.0033 0.0113
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Trypanosoma cruzi cytochrome P450, putative 0.0084 0.0071 0.0239
Trichomonas vaginalis glutathione reductase, putative 0.0185 0.0174 0.0685
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0479 0.0476 0.1612
Echinococcus granulosus rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0049 0.0035 0.0116
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0242 0.0232 0.0915
Mycobacterium ulcerans short chain dehydrogenase 0.0287 0.0279 0.1099
Schistosoma mansoni cpg binding protein 0.0062 0.0048 0.0048
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi nuclear hormone receptor 0.0028 0.0014 0.0046
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Entamoeba histolytica hypothetical protein 0.0107 0.0095 0.4876
Chlamydia trachomatis DNA ligase 0.0027 0.0012 0.0035
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0001 0.0002
Echinococcus granulosus hypothetical protein 0.0016 0.0001 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.0186 0.031
Schistosoma mansoni neuropeptide f receptor 76f 0.0198 0.0187 0.0187
Brugia malayi Guanylate kinase family protein 0.0054 0.004 0.0135
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0491 0.0488 0.1655
Onchocerca volvulus 0.0198 0.0187 0.0631
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0049 0.0035 0.0058
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.003 0.0049
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0005 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0021 0.0077
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0013
Echinococcus granulosus carbonic anhydrase II 0.0461 0.0457 0.0759
Echinococcus multilocularis neuropeptide Y receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) Smad1 0.0016 0.0001 0.0005
Loa Loa (eye worm) matrixin family protein 0.0163 0.0152 0.0516
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0001 0.0005
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0037 0.0023 0.0023
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0049 0.0035 0.176
Schistosoma mansoni alpha glucosidase 0.0044 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Onchocerca volvulus 0.0198 0.0187 0.0631
Echinococcus multilocularis caspase 0.0035 0.0021 0.0034
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.0162 0.0552
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0004 0.0013
Echinococcus multilocularis neuropeptide receptor 0.0198 0.0187 0.0312
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0049 0.0035 0.0116
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0071 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0049 0.0035 0.0116
Brugia malayi Matrixin family protein 0.0074 0.006 0.0204
Brugia malayi Latrophilin receptor protein 2 0.0222 0.0212 0.0718
Trypanosoma cruzi NADH dehydrogenase, putative 0.0049 0.0035 0.0116
Echinococcus granulosus ribonucleoside diphosphate reductase subunit 0.014 0.0129 0.0214
Schistosoma mansoni alpha-glucosidase 0.0169 0.0158 0.0158
Schistosoma mansoni sodium/chloride dependent transporter 0.0491 0.0488 0.0488
Schistosoma mansoni jumonji domain containing protein 0.0071 0.0058 0.0058
Echinococcus granulosus neuropeptide receptor 0.0198 0.0187 0.0312
Chlamydia trachomatis glutamine binding protein 0.0035 0.002 0.0063
Loa Loa (eye worm) hypothetical protein 0.0701 0.0703 0.2382
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0049 0.0035 0.0119
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0023 0.0086
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.0083 0.0325
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0035 0.0021 0.007
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0004 0.0009
Treponema pallidum nicotinate phosphoribosyltransferase 0.0203 0.0193 0.0649
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0056 0.0042 0.0162
Trypanosoma brucei NADH dehydrogenase 0.0049 0.0035 0.0116
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni MAGUK homolog 0.0017 0.0002 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0014 0.0023
Echinococcus multilocularis neuropeptides capa receptor 0.0198 0.0187 0.0312
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.005 0.0171
Echinococcus granulosus microtubule associated protein 2 0.2066 0.2102 0.3493
Toxoplasma gondii cytochrome p450 superfamily protein 0.0056 0.0042 0.0141
Echinococcus granulosus WW domain containing oxidoreductase 0.0016 0.0001 0.0002
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0069 0.0056 0.0093
Trypanosoma brucei metacaspase 5, putative 0.0035 0.0021 0.0067
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0056 0.0042 0.0162
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0021 0.0068
Echinococcus multilocularis ribonucleoside diphosphate reductase subunit 0.014 0.0129 0.0214
Schistosoma mansoni hypothetical protein 0.0222 0.0212 0.0212
Toxoplasma gondii aspartyl protease ASP3 0.0096 0.0083 0.0282
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0021 0.0079
Schistosoma mansoni MAGUK homolog 0.0016 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0056 0.0042 0.0162
Echinococcus granulosus defective proboscis extension response 0.0037 0.0023 0.0038
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0004 0.0007
Echinococcus granulosus glutamate receptor 2 0.0025 0.001 0.0017
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0003 0.0006
Giardia lamblia DNA damage repair protein 0.002 0.0005 0.0225
Echinococcus granulosus inhibitor of apoptosis protein 0.0069 0.0056 0.0093
Echinococcus multilocularis neuropeptide receptor A26 0.0198 0.0187 0.0312
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0049 0.0035 0.0134
Echinococcus granulosus neuropeptide FF receptor 2 0.0198 0.0187 0.0312
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0025 0.001 0.0017
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0049 0.0035 0.0134
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0126 0.0114 0.0446
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0049 0.0035 0.0116
Mycobacterium leprae Conserved hypothetical protein 0.0056 0.0042 0.0162
Echinococcus granulosus tm gpcr rhodopsin 0.0198 0.0187 0.0312
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0056 0.0042 0.0162
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0004 0.0007
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0288 0.0279 0.0464
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Plasmodium falciparum LCCL domain-containing protein 0.0048 0.0034 0.0111
Mycobacterium leprae putative cytochrome p450 0.0056 0.0042 0.0162
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.003 0.01
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.1097 0.1109 0.1843
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0048 0.016
Brugia malayi jmjC domain containing protein 0.0074 0.0061 0.0207
Schistosoma mansoni tar DNA-binding protein 0.0064 0.005 0.005
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0084 0.0071 0.0275
Treponema pallidum ribonucleotide-diphosphate reductase subunit beta 0.014 0.0129 0.043
Schistosoma mansoni serine-type protease inhibitor 0.0902 0.0909 0.0909
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus granulosus biogenic amine 5HT receptor 0.0198 0.0187 0.0312
Entamoeba histolytica hypothetical protein 0.0107 0.0095 0.4876
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0017 0.0028
Schistosoma mansoni cpg binding protein 0.0059 0.0045 0.0045
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0269 0.026 0.089
Schistosoma mansoni hypothetical protein 0.0479 0.0476 0.0476
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0056 0.0042 0.0162
Giardia lamblia Sgs1 DNA helicase, putative 0.0035 0.002 0.1094
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0107 0.0095 0.0321
Brugia malayi Cytochrome P450 family protein 0.0084 0.0071 0.0239
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0049 0.0035 0.0134
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0056 0.0042 0.0162
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0185 0.0174 0.0685
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0049 0.0035 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0491 0.0488 0.0488
Echinococcus granulosus chromobox protein 1 0.0084 0.0071 0.0118
Echinococcus granulosus G protein coupled receptor 139 0.0198 0.0187 0.0312
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.2852 0.2908 1
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Echinococcus multilocularis dna polymerase eta 0.0095 0.0082 0.0136
Schistosoma mansoni hypothetical protein 0.0053 0.0039 0.0039
Echinococcus granulosus oxidoreductase 0.0016 0.0001 0.0002
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0014 0.0023
Echinococcus granulosus cytochrome P450 2K1 0.0056 0.0042 0.007
Echinococcus multilocularis thyroid hormone receptor alpha 0.0028 0.0014 0.0023
Echinococcus multilocularis sodium and chloride dependent glycine 0.0491 0.0488 0.0811
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.0119 0.0198
Schistosoma mansoni hypothetical protein 0.0205 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Leishmania major RAD51/dmc1 protein 0.0024 0.001 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Echinococcus multilocularis apoptotic protease activating factor 1 0.011 0.0098 0.0163
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0049 0.0035 0.0116
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0004 0.0009
Giardia lamblia Thioredoxin reductase 0.0049 0.0035 0.1953
Schistosoma mansoni integrin beta subunit 0.0188 0.0178 0.0178
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0025 0.0082
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.2894 0.2951 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0037 0.0124
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus granulosus tm gpcr rhodopsin 0.5886 0.6017 1
Echinococcus granulosus neuropeptide s receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) RNA binding protein 0.0064 0.005 0.0171
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0049 0.0035 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Echinococcus multilocularis thioredoxin glutathione reductase 0.0533 0.0531 0.0883
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0014 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0095 0.0158
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0222 0.0212 0.0352
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Schistosoma mansoni carbonic anhydrase-related 0.0233 0.0224 0.0224
Echinococcus granulosus biogenic amine 5HT receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.003 0.01
Brugia malayi Death domain containing protein 0.0046 0.0032 0.0108
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0021 0.0068
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0132 0.012 0.0408
Echinococcus multilocularis g protein coupled receptor 0.0198 0.0187 0.0312
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0037 0.0124
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0037 0.0023 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0064 0.005 0.0084
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0049 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.0491 0.0488 0.1655
Echinococcus multilocularis glutamate synthase 0.0049 0.0035 0.0058
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0056 0.0043 0.0163
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0035 0.002 0.0068
Schistosoma mansoni ATP-dependent RNA Helicase 0.0016 0.0001 0.0001
Echinococcus granulosus neuropeptides capa receptor 0.0198 0.0187 0.0312
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0023 0.0023
Mycobacterium ulcerans adenylylate/guanylate cyclase 0.002 0.0005 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0009 0.0032
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0029 0.0099
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0023 0.0038
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0056 0.0042 0.0162
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0004 0.0007
Plasmodium vivax multidomain scavenger receptor, putative 0.0048 0.0034 0.0111
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0048 0.016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0011
Echinococcus granulosus Protein patched homolog 1 0.0111 0.0098 0.0163
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0002
Trichomonas vaginalis glutamate synthase, putative 0.0049 0.0035 0.0134
Echinococcus multilocularis serotonin receptor 0.0198 0.0187 0.0312
Echinococcus multilocularis cpg binding protein 0.0062 0.0048 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0021 0.0077
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0014 0.0023
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0021 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0039 0.013
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0119 0.0467
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0005
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1655
Trypanosoma brucei cytochrome P450, putative 0.0084 0.0071 0.0239
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0023 0.0086
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.003 0.0112
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0049 0.0035 0.0116
Leishmania major ribonucleoside-diphosphate reductase small chain, putative 0.014 0.0129 0.0438
Trichomonas vaginalis glycogen phosphorylase, putative 0.013 0.0118 0.0464
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.248 0.2526 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0013 0.0045
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0095 0.0095
Entamoeba histolytica glycogen phosphorylase, putative 0.013 0.0118 0.6101
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0016 0.0001 0.0008
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0023 0.0086
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0119 0.0404
Echinococcus granulosus death domain containing protein 0.0046 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0185 0.0174 0.059
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0023 0.0078
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0004 0.0013
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0491 0.0488 0.0488
Mycobacterium ulcerans excinuclease ABC subunit C 0.0017 0.0002 0.0002
Leishmania major DNA damage repair protein, putative 0.002 0.0005 0.0013
Brugia malayi Thioredoxin reductase 0.0533 0.0531 0.1801
Onchocerca volvulus 0.0104 0.0092 0.0307
Trypanosoma cruzi NADH dehydrogenase, putative 0.0049 0.0035 0.0116
Echinococcus multilocularis protein dispatched 1 0.0111 0.0098 0.0163
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0461 0.0457 0.0457
Schistosoma mansoni hypothetical protein 0.0056 0.0042 0.0042
Plasmodium vivax proteasome subunit beta type-1, putative 0.0054 0.0041 0.0135
Entamoeba histolytica hypothetical protein 0.0107 0.0095 0.4876
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Loa Loa (eye worm) phosphofructokinase 0.0131 0.0119 0.0404
Toxoplasma gondii DNA repair protein rad10 subfamily protein 0.0017 0.0002 0.0002
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.0061 0.0101
Schistosoma mansoni chromobox protein 0.0084 0.0071 0.0071
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0049 0.0035 0.0134
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0014 0.0046
Toxoplasma gondii IMP dehydrogenas 0.0107 0.0095 0.0321
Schistosoma mansoni opsin-like receptor 0.0198 0.0187 0.0187
Echinococcus multilocularis neuropeptide FF receptor 2 0.0198 0.0187 0.0312
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0288 0.0279 0.0464
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0014 0.0046
Schistosoma mansoni inhibitor of apoptosis protein 0.0069 0.0056 0.0056
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0017 0.0819
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0014 0.0014
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0049 0.0035 0.0119
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0008 0.0027
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0023 0.0076
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.2852 0.2908 0.2908
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0056 0.0042 0.0141
Loa Loa (eye worm) hypothetical protein 0.0049 0.0035 0.0117
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0023 0.0076
Loa Loa (eye worm) solute carrier family 6 member 4 0.2894 0.2951 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0222 0.0212 0.0352
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0185 0.0174 0.0685
Trypanosoma brucei proteasome beta 6 subunit 0.0054 0.0041 0.0135
Echinococcus granulosus caspase 8 0.0035 0.0021 0.0034
Echinococcus multilocularis fmrfamide receptor 0.0198 0.0187 0.0312
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0004 0.0007
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.2852 0.2908 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.0229 0.0901
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0011 0.0034
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0008 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Leishmania major nicotinate phosphoribosyltransferase, putative 0.0203 0.0193 0.066
Onchocerca volvulus 0.0198 0.0187 0.0631
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0002 0.0003
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0198 0.0187 0.0312
Entamoeba histolytica recQ family helicase, putative 0.0038 0.0023 0.1153
Echinococcus granulosus tissue type plasminogen activator 0.0053 0.0039 0.0065
Schistosoma mansoni glycogen phosphorylase 0.013 0.0118 0.0118
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0081 0.0067 0.0229
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0014 0.0023
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.0119 0.0467
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0004 0.0009
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0049 0.0035 0.0116
Brugia malayi RNA binding protein 0.0064 0.005 0.0171
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0002
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.2852 0.2908 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0185 0.0174 0.0595
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Schistosoma mansoni cell polarity protein 0.0049 0.0035 0.0035
Mycobacterium ulcerans hypothetical protein 0.0192 0.0182 0.0714
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0119 0.0406
Loa Loa (eye worm) TK/ROR protein kinase 0.0058 0.0044 0.0148
Schistosoma mansoni hypothetical protein 0.0198 0.0187 0.0187
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0004 0.0014
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0005 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0023 0.0086
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0021 0.0068
Loa Loa (eye worm) matrixin family protein 0.0178 0.0167 0.0567
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0009 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0056 0.0042 0.0162
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.0203 0.0193 0.0193
Echinococcus multilocularis roundabout 2 0.0037 0.0023 0.0038
Brugia malayi Dehydrogenases, short chain protein 30 0.0016 0.0001 0.0004
Onchocerca volvulus 0.0023 0.0008 0.0024
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0107 0.0095 0.037
Echinococcus granulosus somatostatin receptor 0.0198 0.0187 0.0312
Brugia malayi 6-phosphofructokinase 0.0131 0.0119 0.0404
Onchocerca volvulus 0.0024 0.0009 0.0027
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0119 0.0119
Leishmania major cytochrome p450-like protein 0.0056 0.0042 0.0141
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0014 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0049 0.0164
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0037 0.0141
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0034 0.0114
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0107 0.0095 0.0321
Schistosoma mansoni blooms syndrome DNA helicase 0.0032 0.0018 0.0018
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0242 0.0232 0.0915
Plasmodium falciparum transporter, putative 0.0491 0.0488 0.1675
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0025 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0014 0.0046
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0016 0.0001 0.0002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.0001 0.0001
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0011 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0001 0.0001
Brugia malayi polk-prov protein 0.0052 0.0038 0.0129
Schistosoma mansoni sulfide quinone reductase 0.0049 0.0035 0.0035
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0004 0.001
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0233 0.0224 0.0759
Brugia malayi dehydrogenases, short chain protein 2 0.0016 0.0001 0.0004
Schistosoma mansoni histamine h1 receptor 0.0198 0.0187 0.0187
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.002 0.0065
Echinococcus granulosus atrial natriuretic peptide receptor 0.0029 0.0015 0.0024
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0017 0.0062
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0049 0.0035 0.0134
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus granulosus dnaJ subfamily B 0.0838 0.0843 0.1401
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0008 0.0027
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0009
Brugia malayi Pre-B cell enhancing factor precursor 0.1097 0.1109 0.3758
Mycobacterium tuberculosis Conserved protein 0.0037 0.0023 0.0086
Brugia malayi beta-lactamase 0.0037 0.0023 0.0078
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0185 0.0174 0.0595
Onchocerca volvulus 0.0037 0.0023 0.0074
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Echinococcus granulosus dna repair protein rad51 1 0.0024 0.001 0.0016
Echinococcus multilocularis netrin receptor unc 5 0.0046 0.0032 0.0053
Brugia malayi hypothetical protein 0.0048 0.0034 0.0114
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0081 0.0067 0.0112
Schistosoma mansoni DNA helicase recq5 0.0035 0.002 0.002
Chlamydia trachomatis glycogen phosphorylase 0.013 0.0118 0.0401
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0035 0.0021 0.0034
Loa Loa (eye worm) dehydrogenase 0.0016 0.0001 0.0004
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0021 0.0068
Trypanosoma cruzi DNA repair protein RAD51, putative 0.0024 0.001 0.0029
Brugia malayi Pre-SET motif family protein 0.0253 0.0244 0.0826
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0038 0.0127
Leishmania major NADH dehydrogenase, putative 0.0049 0.0035 0.0116
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Echinococcus granulosus rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Echinococcus granulosus Ankyrin 0.0046 0.0032 0.0053
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0222 0.0212 0.0352
Schistosoma mansoni cell polarity protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0084
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0233 0.0224 0.0759
Brugia malayi Matrixin family protein 0.0074 0.006 0.0204
Echinococcus multilocularis smad 0.0016 0.0001 0.0002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0198 0.0187 0.0635
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.0098 0.0098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Echinococcus granulosus rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0032
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0069 0.0056 0.019
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0119 0.0404
Schistosoma mansoni neuropeptide receptor 0.0198 0.0187 0.0187
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0035 0.002 0.0063
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0003 0.0003
Echinococcus granulosus 7TM GPCR rhodopsin 0.0198 0.0187 0.0312
Plasmodium vivax ribonucleoside-diphosphate reductase small chain, putative 0.014 0.0129 0.0438
Plasmodium vivax aspartyl proteinase, putative 0.0096 0.0083 0.0282
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.248 0.2526 1
Mycobacterium ulcerans hypothetical protein 0.0049 0.0035 0.0134
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Wolbachia endosymbiont of Brugia malayi Holliday junction DNA helicase RuvA 0.0017 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.003 0.0112
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.0203 0.0193 0.066
Echinococcus multilocularis sodium and chloride dependent glycine 0.0491 0.0488 0.0811
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.0359 0.1229
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0033 0.0108
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.014 0.0129 0.0438
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0671 0.0673 0.1118
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0013
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0035 0.002 0.0068
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0185 0.0174 0.0595
Schistosoma mansoni maguk P55 subfamily member 35 0.0016 0.0001 0.0001
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0021 0.0068
Onchocerca volvulus Deterin homolog 0.0069 0.0056 0.0186
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0014 0.0042
Schistosoma mansoni lipoxygenase 0.0133 0.0121 0.0121
Echinococcus granulosus neuroglian 0.0037 0.0023 0.0039
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0107 0.0095 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0021 0.0077
Trypanosoma cruzi trypanothione reductase, putative 0.0185 0.0174 0.0595
Echinococcus granulosus g protein coupled receptor 0.0198 0.0187 0.0312
Echinococcus granulosus MAGUK p55 subfamily 0.0016 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0056 0.0042 0.0162
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0049 0.0035 0.0116
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0008 0.0023
Echinococcus granulosus Smad4 0.0016 0.0001 0.0002
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0049 0.0035 0.0058
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0048 0.016
Onchocerca volvulus 0.0198 0.0187 0.0631
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.2894 0.2951 0.2951
Trypanosoma cruzi metacaspase, putative 0.0035 0.0021 0.0067
Schistosoma mansoni hypothetical protein 0.0198 0.0187 0.0187
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0049 0.0035 0.0134
Echinococcus multilocularis bloom syndrome protein 0.005 0.0036 0.0059
Brugia malayi Heterochromatin protein 1 0.0084 0.0071 0.0241
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0044 0.003 0.0049
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0049 0.0035 0.0058
Loa Loa (eye worm) TYRA-2 protein 0.0198 0.0187 0.0635
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0049 0.0035 0.0116
Echinococcus granulosus sterol regulatory element binding protein 0.0111 0.0098 0.0163
Schistosoma mansoni hypothetical protein 0.0049 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0838 0.0843 0.0843
Schistosoma mansoni hypothetical protein 0.0187 0.0176 0.0176
Schistosoma mansoni tyrosine kinase 0.0016 0.0001 0.0001
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0107 0.0095 0.0095
Echinococcus granulosus hypothetical protein 0.0198 0.0187 0.0312
Onchocerca volvulus 0.0198 0.0187 0.0631
Trypanosoma brucei unspecified product 0.0088 0.0075 0.0254
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0119 0.0467
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0032 0.0108
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0198 0.0187 0.0635
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (beta chain) NrdF1 (ribonucleotide reductase small subunit) (R2F protein) 0.014 0.0129 0.0504
Brugia malayi steroid hormone receptor 0.0028 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Mycobacterium tuberculosis Probable transcriptional regulatory protein NrdR 0.0372 0.0367 0.1447
Schistosoma mansoni DNA repair protein RAD51 0.0024 0.001 0.001
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0096 0.0083 0.0325
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0069 0.0056 0.019
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0491 0.0488 0.0488
Trichomonas vaginalis mercuric reductase, putative 0.0185 0.0174 0.0685
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0017 0.0002 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0046 0.0032 0.0108
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0035 0.002 0.0062
Schistosoma mansoni retinal dehydrogenase 0.0016 0.0001 0.0001
Plasmodium falciparum carbonic anhydrase 0.0233 0.0224 0.0766
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0009
Schistosoma mansoni opsin-like receptor 0.0198 0.0187 0.0187
Loa Loa (eye worm) MH2 domain-containing protein 0.0238 0.0229 0.0775
Plasmodium falciparum plasmepsin X 0.0096 0.0083 0.0282
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0049 0.0035 0.0134
Echinococcus multilocularis carbonic anhydrase 0.0233 0.0224 0.0372
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1675
Entamoeba histolytica disulphide oxidoreductase, putative 0.0049 0.0035 0.176
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0081 0.0067 0.0262
Loa Loa (eye worm) G-protein coupled receptor 0.0198 0.0187 0.0635
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0035 0.002 0.0034
Brugia malayi ribonucleotide reductase 2 0.014 0.0129 0.0436
Schistosoma mansoni lipoxygenase 0.0048 0.0034 0.0034
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0035 0.002 0.0068
Schistosoma mansoni sodium/chloride dependent transporter 0.0492 0.0489 0.0489
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0077
Echinococcus multilocularis tyrosine kinase 0.0016 0.0001 0.0002
Brugia malayi TAR-binding protein 0.0064 0.005 0.0171
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0051 0.0037 0.0122
Plasmodium vivax aspartyl proteinase, putative 0.0132 0.012 0.041
Onchocerca volvulus Neuropeptide F receptor homolog 0.0198 0.0187 0.0631
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.001
Onchocerca volvulus 0.0198 0.0187 0.0631
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0021 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Brugia malayi Dehydrogenases, short chain protein 2 0.0016 0.0001 0.0004
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0269 0.026 0.089
Giardia lamblia DNA helicase 0.0017 0.0002 0.0029
Entamoeba histolytica recQ family helicase, putative 0.0017 0.0002 0.0045
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0035 0.0021 0.0067
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0014 0.0023
Mycobacterium tuberculosis Probable reductase 0.0242 0.0232 0.0915
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0233 0.0224 0.0759
Onchocerca volvulus 0.0098 0.0085 0.0284
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0004 0.001
Schistosoma mansoni neuropeptide receptor 0.0198 0.0187 0.0187
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0198 0.0187 0.0635
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0016 0.0001 0.0002
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0002 0.0002
Trypanosoma brucei Metacaspase-4 0.0035 0.0021 0.0067
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.006 0.0046 0.0178
Echinococcus granulosus smad 0.0016 0.0001 0.0002
Onchocerca volvulus 0.0051 0.0037 0.0122
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0054 0.0041 0.0067
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.248 0.2526 1
Echinococcus multilocularis retinol dehydrogenase 13 0.0016 0.0001 0.0002
Plasmodium vivax plasmepsin V, putative 0.0096 0.0083 0.0282
Onchocerca volvulus 0.0096 0.0083 0.0278
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0001 0.0002
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0054 0.0041 0.0135
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.0119 0.0198
Echinococcus multilocularis allatostatin A receptor 0.0198 0.0187 0.0312
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0023 0.0078
Loa Loa (eye worm) hypothetical protein 0.0049 0.0035 0.0119
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Toxoplasma gondii aspartyl protease 0.0096 0.0083 0.0282
Echinococcus granulosus steroid dehydrogenase 0.0016 0.0001 0.0002
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0002
Mycobacterium leprae PROBABLE HYDROLASE 0.009 0.0077 0.0299
Echinococcus granulosus glutamate synthase 0.0049 0.0035 0.0058
Entamoeba histolytica DNA repair protein RAD51, putative 0.0024 0.001 0.0446
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0011 0.0034
Echinococcus multilocularis chromobox protein 1 0.0084 0.0071 0.0118
Entamoeba histolytica recQ family DNA helicase 0.0018 0.0003 0.0081
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0049 0.0035 0.0116
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0016 0.0001 0.0002
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0017 0.0002 0.0003
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0008 0.0013
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0198 0.0187 0.0312
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0004 0.0004
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0048 0.2692
Echinococcus multilocularis carbonic anhydrase 0.0233 0.0224 0.0372
Brugia malayi putative neuropeptide receptor NPR1 0.0198 0.0187 0.0635
Schistosoma mansoni excision repair cross-complementing 1 ercc1 0.0017 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0011 0.0039
Schistosoma mansoni smad1 5 8 and 0.0016 0.0001 0.0001
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0046 0.0032 0.0053
Onchocerca volvulus 0.0198 0.0187 0.0631
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0198 0.0187 0.0312
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0701 0.0703 0.2382
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Schistosoma mansoni ankyrin 23/unc44 0.0046 0.0032 0.0032
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0461 0.0457 0.0457
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0049 0.0035 0.0134
Echinococcus multilocularis lamin dm0 0.0081 0.0068 0.0113
Brugia malayi latrophilin 2 splice variant baaae 0.0479 0.0476 0.1612
Echinococcus multilocularis neuropeptide Y receptor 0.0198 0.0187 0.0312
Brugia malayi Matrixin family protein 0.0178 0.0167 0.0567
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.2852 0.2908 0.4833
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0014 0.0046
Echinococcus granulosus dna polymerase eta 0.0095 0.0082 0.0136
Brugia malayi Serotonin receptor 0.0198 0.0187 0.0635
Brugia malayi Calcitonin receptor-like protein seb-1 0.0701 0.0703 0.2382
Onchocerca volvulus 0.0198 0.0187 0.0631
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0269 0.026 0.0881
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0021 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0035 0.002 0.0034
Toxoplasma gondii hypothetical protein 0.0491 0.0488 0.1675
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0233 0.0224 0.0759
Loa Loa (eye worm) glutathione reductase 0.0533 0.0531 0.1801
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0198 0.0187 0.0312
Schistosoma mansoni growth hormone secretagogue receptor 0.0198 0.0187 0.0187
Trypanosoma cruzi trypanothione reductase, putative 0.0533 0.0531 0.1824
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0288 0.0279 0.0947
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0004 0.0009
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0001 0.0002
Schistosoma mansoni nephrin 0.0037 0.0023 0.0023
Trypanosoma brucei metacaspase MCA3 0.0035 0.0021 0.0067
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0491 0.0488 0.0488
Loa Loa (eye worm) carbonic anhydrase 3 0.0461 0.0457 0.1548
Loa Loa (eye worm) neuropeptide F receptor 0.0198 0.0187 0.0635
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0233 0.0224 0.0759
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0023 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0009 0.0032
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0056 0.0042 0.0162
Brugia malayi oxidoreductase 0.0016 0.0001 0.0004
Echinococcus multilocularis musashi 0.0081 0.0068 0.0113
Schistosoma mansoni hypothetical protein 0.0288 0.0279 0.0279
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0491 0.0488 0.0811
Schistosoma mansoni amine GPCR 0.0198 0.0187 0.0187
Brugia malayi Kringle domain containing protein 0.0053 0.0039 0.0133
Loa Loa (eye worm) RecQ helicase 0.005 0.0036 0.0121
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Echinococcus granulosus RUN 0.0048 0.0034 0.0056
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0056 0.0042 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0014 0.0046
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0016 0.0001 0.0002
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0461 0.0457 0.1548
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0021 0.0077
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.2852 0.2908 0.9856
Brugia malayi Cytochrome P450 family protein 0.0177 0.0166 0.0563
Echinococcus multilocularis orexin receptor type 2 0.0198 0.0187 0.0312
Loa Loa (eye worm) apoptosis regulator protein 0.0288 0.0279 0.0947
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0491 0.0488 0.0488
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0491 0.0488 0.1655
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.0203 0.0193 0.076
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0017 0.0058
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0185 0.0174 0.0595
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Schistosoma mansoni caspase-3 (C14 family) 0.0035 0.0021 0.0021
Mycobacterium ulcerans ferredoxin reductase 0.0049 0.0035 0.0134
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0017 0.0054
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0023 0.0086
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0198 0.0187 0.0312
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0047 0.0033 0.0113
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0025 0.0082
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0023 0.0086
Trypanosoma cruzi metacaspase, putative 0.0035 0.0021 0.0067
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0056 0.0042 0.0162
Schistosoma mansoni polycystin 1-related 0.0048 0.0034 0.0034
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.1777 0.1806 0.1806
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Onchocerca volvulus 0.0028 0.0014 0.0042
Brugia malayi neuropeptide F receptor 0.0198 0.0187 0.0635
Brugia malayi Dopamine receptor 0.0198 0.0187 0.0635
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0009 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0013 0.0045
Schistosoma mansoni cytochrome P450 0.0056 0.0042 0.0042
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0016 0.0001 0.0004
Trichomonas vaginalis set domain proteins, putative 0.0287 0.0279 0.1101
Echinococcus granulosus carbonic anhydrase 0.0233 0.0224 0.0372
Brugia malayi Serotonin receptor 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0052 0.0038 0.0129
Trypanosoma cruzi GMP reductase 0.0107 0.0095 0.0321
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0058 0.0096
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0049 0.0035 0.0116
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0014 0.0014
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0064 0.005 0.0171
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Brugia malayi Receptor family ligand binding region containing protein 0.0036 0.0022 0.0074
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0004 0.0009
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0004 0.0009
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0074 0.006 0.006
Echinococcus multilocularis Kelch repeat type 1 0.0187 0.0176 0.0293
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0002
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0185 0.0174 0.0685
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0014 0.0046
Echinococcus granulosus dro:myosuppressin receptor 0.0198 0.0187 0.0312
Brugia malayi Dopamine receptor protein 2 0.0198 0.0187 0.0635
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0004 0.0004
Loa Loa (eye worm) histone methyltransferase 0.002 0.0005 0.0016
Echinococcus multilocularis G-protein coupled receptor, putative 0.0198 0.0187 0.0312
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0009 0.0032
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0035 0.0021 0.0067
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Trichomonas vaginalis DNA helicase recq1, putative 0.005 0.0036 0.0136
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0037 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0014
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus allatostatin A receptor 0.0198 0.0187 0.0312
Mycobacterium ulcerans hypothetical protein 0.002 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Brugia malayi GnHR receptor homolog 0.0198 0.0187 0.0635
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.2852 0.2908 1
Echinococcus multilocularis g protein coupled receptor 0.0198 0.0187 0.0312
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0107 0.0095 0.0321
Brugia malayi Kelch motif family protein 0.0049 0.0035 0.0117
Echinococcus multilocularis 0.0056 0.0042 0.007
Loa Loa (eye worm) doublecortin family protein 0.0048 0.0034 0.0114
Schistosoma mansoni neuropeptide F-like receptor 0.0198 0.0187 0.0187
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0198 0.0187 0.0312
Onchocerca volvulus 0.0081 0.0068 0.0226
Brugia malayi intermediate filament protein 0.0081 0.0068 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0033 0.0126
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0049 0.0035 0.0134
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0014 0.0014
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0056 0.0042 0.0162
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0046 0.0032 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1655
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0023 0.0075
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0132 0.012 0.0472
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0014 0.0023
Schistosoma mansoni smad 0.0016 0.0001 0.0001
Plasmodium vivax metacaspase 1, putative 0.0035 0.0021 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Loa Loa (eye worm) integrin beta-2 0.032 0.0312 0.1058
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0068 0.023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1167 0.1181 0.1963
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni hypothetical protein 0.0198 0.0187 0.0187
Echinococcus granulosus sodium and chloride dependent glycine 0.0491 0.0488 0.0811
Schistosoma mansoni neuropeptide receptor 0.0198 0.0187 0.0187
Plasmodium falciparum plasmepsin VIII, putative 0.0096 0.0083 0.0282
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0049 0.0035 0.0116
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0056 0.0042 0.0162
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0001 0.0001
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.0203 0.0193 0.076
Trypanosoma cruzi DNA repair protein RAD51, putative 0.0024 0.001 0.0029
Schistosoma mansoni hypothetical protein 0.0205 0.0194 0.0194
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0014 0.0014
Loa Loa (eye worm) TAR-binding protein 0.0064 0.005 0.0171
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0021 0.0068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Echinococcus granulosus dna polymerase kappa 0.0096 0.0083 0.0139
Loa Loa (eye worm) hypothetical protein 0.0288 0.0279 0.0947
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0056 0.0042 0.0162
Leishmania major hypothetical protein, conserved 0.0049 0.0035 0.0116
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1655
Mycobacterium ulcerans transcriptional regulator NrdR 0.0372 0.0367 0.1447
Plasmodium vivax aspartyl protease, putative 0.0096 0.0083 0.0282
Schistosoma mansoni terminal deoxycytidyl transferase 0.0064 0.005 0.005
Brugia malayi ImpB/MucB/SamB family protein 0.0095 0.0082 0.0278
Schistosoma mansoni vesicular amine transporter 0.0037 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0288 0.0279 0.0279
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0049 0.0035 0.176
Loa Loa (eye worm) hypothetical protein 0.0096 0.0083 0.0282
Echinococcus granulosus carbonic anhydrase 0.0233 0.0224 0.0372
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0049 0.0035 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.1167 0.1181 0.1963
Echinococcus multilocularis MAGUK p55 subfamily 0.0016 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0111 0.0098 0.0098
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0004 0.001
Mycobacterium ulcerans hypothetical protein 0.0024 0.0009 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0002 0.0003
Mycobacterium ulcerans hypothetical protein 0.0037 0.0023 0.0086
Loa Loa (eye worm) dehydrogenase 0.0016 0.0001 0.0004
Echinococcus granulosus roundabout 2 0.0037 0.0023 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Plasmodium vivax plasmepsin IV, putative 0.0132 0.012 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Loa Loa (eye worm) cytochrome P450 family protein 0.0084 0.0071 0.0239
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis caspase 2 0.0145 0.0134 0.0222
Schistosoma mansoni glutamate synthase 0.0049 0.0035 0.0035
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0021 0.0068
Plasmodium falciparum metacaspase 1 0.0035 0.0021 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Schistosoma mansoni caspase-7 (C14 family) 0.0035 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0074 0.006 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Onchocerca volvulus 0.0198 0.0187 0.0631
Loa Loa (eye worm) hypothetical protein 0.2894 0.2951 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0014 0.0046
Brugia malayi Melatonin receptor type 1A 0.0198 0.0187 0.0635
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0004 0.001
Entamoeba histolytica deoxycytidyl transferase, putative 0.0064 0.005 0.2562
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0081 0.0067 0.0262
Echinococcus granulosus receptor type guanylyl cyclase 0.0036 0.0022 0.0036
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0076 0.0126
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0008 0.0353
Plasmodium vivax glutathione reductase, putative 0.0533 0.0531 0.1824
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Plasmodium falciparum plasmepsin I 0.0132 0.012 0.041
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0185 0.0174 0.0595
Brugia malayi Dopamine receptor protein 1 0.0198 0.0187 0.0635
Schistosoma mansoni carbonic anhydrase-related 0.0233 0.0224 0.0224
Mycobacterium ulcerans lipase LipD 0.0037 0.0023 0.0086
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0009 0.0422
Brugia malayi Smad1 0.0016 0.0001 0.0005
Brugia malayi aspartic protease BmAsp-1, identical 0.0096 0.0083 0.0282
Schistosoma mansoni neuropeptide F-like receptor 0.0198 0.0187 0.0187
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0162 0.0552
Plasmodium falciparum plasmepsin VI 0.0132 0.012 0.041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Giardia lamblia Glutamate synthase 0.0049 0.0035 0.1953
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0026 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0014 0.0046
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0056 0.0042 0.0162
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0107 0.0095 0.037
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.005 0.0171
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Brugia malayi phosphofructokinase 0.0131 0.0119 0.0404
Onchocerca volvulus Glycogen phosphorylase homolog 0.013 0.0118 0.0397
Echinococcus granulosus sex peptide receptor 0.0198 0.0187 0.0312
Brugia malayi proteasome subunit beta type 1 0.0054 0.0041 0.0137
Loa Loa (eye worm) hypothetical protein 0.0074 0.006 0.0204
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0198 0.0187 0.0187
Onchocerca volvulus 0.0198 0.0187 0.0631
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0107 0.0095 0.0321
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis dna repair protein rad51 1 0.0024 0.001 0.0016
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0014 0.0014
Echinococcus multilocularis carbonic anhydrase II 0.0461 0.0457 0.0759
Loa Loa (eye worm) hypothetical protein 0.009 0.0077 0.026
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0198 0.0187 0.0187
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0017 0.0054
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0035 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0132 0.012 0.012
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0021 0.0066
Onchocerca volvulus Netrin receptor homolog 0.0046 0.0032 0.0104
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0049 0.0035 0.0134
Brugia malayi Sodium:neurotransmitter symporter family protein 0.2894 0.2951 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.003 0.1471
Echinococcus granulosus lamin dm0 0.0081 0.0068 0.0113
Schistosoma mansoni glutamate synthase 0.0049 0.0035 0.0035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0013 0.0045
Echinococcus granulosus tar DNA binding protein 0.0064 0.005 0.0084
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Brugia malayi Tachykinin-like peptides receptor 99D 0.0198 0.0187 0.0635
Schistosoma mansoni cell adhesion molecule 0.0037 0.0023 0.0023
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0054 0.0041 0.0135
Trichomonas vaginalis esterase, putative 0.0037 0.0023 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0005 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0008 0.0023
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0049 0.0035 0.0116
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0185 0.0174 0.0595
Echinococcus multilocularis tissue type plasminogen activator 0.0053 0.0039 0.0065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0023 0.0078
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0198 0.0187 0.0312
Schistosoma mansoni hypothetical protein 0.0046 0.0032 0.0032
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0042 0.0028 0.0094
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.0186 0.0632
Loa Loa (eye worm) hypothetical protein 0.0491 0.0488 0.1655
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0025 0.1243
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0222 0.0212 0.0352
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0014 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Plasmodium vivax amine transporter, putative 0.0491 0.0488 0.1675
Echinococcus multilocularis GPCR, family 2 0.0222 0.0212 0.0352
Onchocerca volvulus 0.0019 0.0004 0.0009
Echinococcus multilocularis neuropeptides capa receptor 0.0398 0.0393 0.0653
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0044 0.003 0.0049
Brugia malayi hypothetical protein 0.0037 0.0023 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.002
Trypanosoma brucei trypanothione reductase 0.0533 0.0531 0.1824
Trypanosoma cruzi cytochrome P450, putative 0.0084 0.0071 0.0239
Plasmodium vivax SET domain protein, putative 0.0037 0.0023 0.0075
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0491 0.0488 0.0488
Echinococcus granulosus nmda type glutamate receptor 0.0048 0.0034 0.0056
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0018 0.0003 0.0005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.0058 0.0096
Mycobacterium tuberculosis Probable holliday junction DNA helicase RuvA 0.0017 0.0002 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0056 0.0042 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0038 0.0127
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0049 0.0035 0.0116
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0004 0.014
Echinococcus multilocularis 0.0016 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0056 0.0042 0.0162
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0001 0.0001
Leishmania major cytochrome p450-like protein 0.0056 0.0042 0.0141
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0023 0.0086
Echinococcus granulosus alpha 1A adrenergic receptor 0.0198 0.0187 0.0312
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0001 0.0001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.005 0.005
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0198 0.0187 0.0312
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.2852 0.2908 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0038 0.0127
Brugia malayi Guanylyl cyclase protein 23 0.0019 0.0004 0.0013
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0048 0.0079
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0085 0.0288
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0005 0.0013
Trypanosoma cruzi metacaspase, putative 0.0035 0.0021 0.0067
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.003 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Echinococcus granulosus MAGUK p55 subfamily 0.0016 0.0001 0.0002
Plasmodium falciparum glutathione reductase 0.0533 0.0531 0.1824
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0049 0.0035 0.0134
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0491 0.0488 0.1655
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) 0.0892 0.0899 0.3553
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0126 0.0114 0.0446
Mycobacterium ulcerans glutamate synthase subunit beta 0.0049 0.0035 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0048 0.0184
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Brugia malayi G protein-coupled receptor F59B2.13 0.0198 0.0187 0.0635
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.003 0.0112
Schistosoma mansoni amine GPCR 0.0198 0.0187 0.0187
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0233 0.0224 0.0759
Mycobacterium tuberculosis Conserved protein 0.0037 0.0023 0.0086
Echinococcus multilocularis geminin 0.0205 0.0194 0.0323
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0056 0.0042 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Schistosoma mansoni survival motor neuron protein 0.0098 0.0085 0.0085
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0015 0.0048
Mycobacterium tuberculosis Probable oxidoreductase 0.0287 0.0279 0.1099
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Mycobacterium ulcerans monoxygenase 0.0049 0.0035 0.0134
Toxoplasma gondii thioredoxin reductase 0.0533 0.0531 0.1824
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.003 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.003 0.0112
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0023 0.0086
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0056 0.0042 0.0162
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0198 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0222 0.0212 0.0212
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0009 0.0422
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0023 0.0075
Trypanosoma cruzi meiotic recombination protein DMC1, putative 0.0024 0.001 0.0029
Toxoplasma gondii exonuclease III APE 0.0023 0.0008 0.0023
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0016 0.0001 0.0002
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0004 0.0009
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0119 0.6148
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0048 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Trypanosoma brucei unspecified product 0.0044 0.003 0.0099
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0056 0.0042 0.0141
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative 0.2852 0.2908 0.9856
Plasmodium falciparum ribonucleoside-diphosphate reductase small chain, putative 0.0048 0.0034 0.0111
Brugia malayi G-protein coupled receptor 0.0198 0.0187 0.0635
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0491 0.0488 0.0811
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0004 0.0013
Trypanosoma brucei RNA helicase, putative 0.0111 0.0098 0.0333
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0048 0.0184
Brugia malayi Retinol dehydrogenase 12 0.0016 0.0001 0.0004
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0004 0.0009
Brugia malayi ORL1-like opioid receptor 0.0198 0.0187 0.0635
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0004 0.0007
Schistosoma mansoni cathepsin D (A01 family) 0.0225 0.0215 0.0215
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0003 0.0007
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0198 0.0187 0.0631
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0017 0.0054
Loa Loa (eye worm) melatonin receptor type 1A 0.0198 0.0187 0.0635
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0014 0.0046
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0048 0.0034 0.0056
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Trichomonas vaginalis DNA polymerase eta, putative 0.0096 0.0083 0.0325
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0081 0.0067 0.0262
Echinococcus granulosus cpg binding protein 0.0062 0.0048 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.1097 0.1109 0.1109
Schistosoma mansoni opsin-like receptor 0.0198 0.0187 0.0187
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN) 0.0048 0.0034 0.0128
Mycobacterium ulcerans dehydrogenase 0.0049 0.0035 0.0134
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0035 0.0021 0.0034
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0049 0.0035 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0021 0.0079
Brugia malayi hypothetical protein 0.0147 0.0135 0.0459
Echinococcus granulosus neuropeptide receptor 0.0198 0.0187 0.0312
Echinococcus multilocularis tar DNA binding protein 0.0064 0.005 0.0084
Schistosoma mansoni tumor necrosis factor receptor related 0.0044 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0222 0.0212 0.0718
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0119 0.0467
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0014 0.0014
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0132 0.012 0.041
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0011 0.0034
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0491 0.0488 0.1675
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0461 0.0457 0.1548
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0185 0.0174 0.0595
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Leishmania major carbonic anhydrase-like protein 0.0461 0.0457 0.1567
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0004 0.0007
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.002 0.0065
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0269 0.026 0.026
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0004 0.0007
Onchocerca volvulus Putative GMP reductase 0.0047 0.0033 0.0109
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0185 0.0174 0.0685
Echinococcus granulosus integrin beta 2 0.0237 0.0227 0.0378
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0185 0.0174 0.0595
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0035 0.0116
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0009 0.0032
Giardia lamblia Proteasome subunit beta type 1 0.0054 0.0041 0.227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0014 0.0046
Echinococcus multilocularis dro:myosuppressin receptor 0.0198 0.0187 0.0312
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.005 0.0036 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0009 0.0032
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0083 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0023 0.0075
Loa Loa (eye worm) hypothetical protein 0.0233 0.0224 0.0759
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0269 0.026 0.0432
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0017 0.0054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0056 0.0042 0.0162
Plasmodium falciparum plasmepsin III 0.0096 0.0083 0.0282
Echinococcus multilocularis RUN 0.0048 0.0034 0.0056
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.003 0.1471
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.0203 0.0193 1
Schistosoma mansoni loxhd1 0.0048 0.0034 0.0034
Trypanosoma brucei carbonic anhydrase-like protein 0.0461 0.0457 0.1567
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0056 0.0042 0.0162
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0025 0.001 0.0017
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0049 0.0035 0.0116
Brugia malayi GMP reductase 0.0047 0.0033 0.0113
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0004 0.0009
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0288 0.0279 0.0279
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0049 0.0035 0.0134
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0109
Echinococcus multilocularis Immunoglobulin 0.0037 0.0023 0.0038
Echinococcus multilocularis disks large 3 0.0049 0.0035 0.0058
Echinococcus multilocularis serotonin receptor 0.0198 0.0187 0.0312
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0359 0.1229
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0049 0.0035 0.0134
Brugia malayi aspartic protease BmAsp-2, identical 0.0096 0.0083 0.0282
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0701 0.0703 0.2382
Echinococcus multilocularis inhibitor of apoptosis protein 0.0069 0.0056 0.0093
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0004 0.0009
Schistosoma mansoni smad1 5 8 and 0.0016 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0009 0.0032
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0008 0.0027
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0132 0.012 0.02
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0056 0.0042 0.0162
Trichomonas vaginalis meiosis-specific recA homolog Dmc1 0.0024 0.001 0.0034
Echinococcus multilocularis Glycosyl transferase, family 35 0.013 0.0118 0.0197
Brugia malayi follicle stimulating hormone receptor 0.0198 0.0187 0.0635
Entamoeba histolytica glycogen phosphorylase, putative 0.0056 0.0043 0.215
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0038 0.0127
Loa Loa (eye worm) thioredoxin reductase 0.0533 0.0531 0.1801
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0491 0.0488 0.0811
Echinococcus granulosus g-protein coupled receptor 0.0198 0.0187 0.0312
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Brugia malayi neuropeptide F receptor 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0003 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0014 0.0046
Onchocerca volvulus Matrix metalloproteinase homolog 0.0163 0.0152 0.0512
Schistosoma mansoni hypothetical protein 0.0069 0.0056 0.0056
Echinococcus multilocularis Ankyrin 0.0046 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0461 0.0457 0.1548
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0269 0.026 0.089
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0233 0.0224 0.0759
Schistosoma mansoni disulfide oxidoreductase 0.0049 0.0035 0.0035
Schistosoma mansoni flap endonuclease-1 0.0028 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0014 0.0046
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0047 0.0033 0.0127
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0023 0.0086
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0185 0.0174 0.0593
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0061 0.0061
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Toxoplasma gondii ABC1 family protein 0.0037 0.0023 0.0075
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0008 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0021 0.0077
Plasmodium falciparum DNA repair protein REV1, putative 0.002 0.0005 0.0013
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0016 0.0001 0.0002
Schistosoma mansoni myosin xvIII 0.0198 0.0187 0.0187
Onchocerca volvulus 0.0096 0.0083 0.0278
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.2852 0.2908 0.9856
Brugia malayi dehydrogenases, short chain protein 9 0.0016 0.0001 0.0004
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0049 0.0035 0.176
Plasmodium falciparum ribonucleoside-diphosphate reductase small chain, putative 0.014 0.0129 0.0438
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.248 0.2526 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.0079
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0048 0.0079
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0004
Echinococcus multilocularis kelch ECH associated protein 1 0.0186 0.0176 0.0292
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.0203 0.0193 0.066
Brugia malayi glutamate synthase 0.0049 0.0035 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Leishmania major cytochrome p450-like protein 0.0084 0.0071 0.0239
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0049 0.0035 0.0134
Brugia malayi Flap endonuclease-1 0.0031 0.0017 0.0058
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0025 0.0041
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.0203 0.0193 0.076
Schistosoma mansoni ap endonuclease 0.0023 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Echinococcus multilocularis somatostatin receptor 0.0198 0.0187 0.0312
Echinococcus multilocularis g-protein coupled receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0014 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0023 0.0023
Echinococcus multilocularis G protein coupled receptor 139 0.0198 0.0187 0.0312
Schistosoma mansoni patched 1 0.0111 0.0098 0.0098
Schistosoma mansoni glycogen phosphorylase 0.013 0.0118 0.0118
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0136 0.0124 0.042
Echinococcus granulosus carbonic anhydrase 0.0233 0.0224 0.0372
Schistosoma mansoni sulfide quinone reductase 0.0049 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0383 0.0377 0.1279
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0461 0.0457 0.1567
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0056 0.0042 0.0162
Leishmania major DNA polymerase eta, putative 0.0095 0.0082 0.0278
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0198 0.0187 0.0312
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0009 0.0032
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0001 0.0002
Brugia malayi Protein kinase domain containing protein 0.0047 0.0032 0.011
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0049 0.0035 0.0134
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0048 0.0079
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0049 0.0035 0.0134
Trypanosoma cruzi meiotic recombination protein DMC1, putative 0.0024 0.001 0.0029
Echinococcus granulosus GPCR family 2 0.0222 0.0212 0.0352
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0048 0.016
Mycobacterium ulcerans Holliday junction DNA helicase RuvA 0.0017 0.0002 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0008 0.0027
Schistosoma mansoni rab6-interacting 0.0048 0.0034 0.0034
Echinococcus granulosus g protein coupled receptor 0.0198 0.0187 0.0312
Plasmodium vivax JmjC domain containing protein 0.0019 0.0004 0.001
Trypanosoma cruzi GMP reductase 0.0107 0.0095 0.0321
Brugia malayi chromobox protein homolog 3 0.0047 0.0033 0.0112
Brugia malayi jmjC domain containing protein 0.0071 0.0058 0.0195
Schistosoma mansoni alpha-glucosidase 0.0169 0.0158 0.0158
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0242 0.0232 0.0915
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0014 0.0046
Schistosoma mansoni tyrosine kinase 0.0016 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0048 0.0034 0.0114
Echinococcus multilocularis fmrfamide receptor 0.0198 0.0187 0.0312
Schistosoma mansoni Smad4 0.0016 0.0001 0.0001
Plasmodium falciparum flap endonuclease 1 0.0031 0.0017 0.0054
Echinococcus granulosus MAGUK p55 subfamily 0.0016 0.0001 0.0002
Onchocerca volvulus 0.0053 0.0039 0.0129
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0107 0.0095 0.0321
Echinococcus multilocularis MAGUK p55 subfamily 0.0016 0.0001 0.0002
Brugia malayi CXXC zinc finger family protein 0.0059 0.0045 0.0153
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0056 0.0042 0.0162
Leishmania major glycosyl hydrolase-like protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) norepinephrine transporter 0.2894 0.2951 1
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0023 0.0086
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.003 0.0097
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0008 0.0023
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0491 0.0488 0.0811
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Trypanosoma cruzi metacaspase 5, putative 0.0035 0.0021 0.0067
Onchocerca volvulus 0.0198 0.0187 0.0631
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0136 0.0124 0.042
Echinococcus granulosus caspase 2 0.0145 0.0134 0.0222
Loa Loa (eye worm) cytochrome P450 family protein 0.0177 0.0166 0.0563
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0098
Schistosoma mansoni hypothetical protein 0.0288 0.0279 0.0279
Schistosoma mansoni amine GPCR 0.0198 0.0187 0.0187
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0016 0.0001 0.0001
Echinococcus granulosus thioredoxin glutathione reductase 0.0533 0.0531 0.0883
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.2852 0.2908 0.4833
Brugia malayi Cytochrome P450 family protein 0.0056 0.0042 0.0143
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Echinococcus multilocularis microtubule associated protein 2 0.2066 0.2102 0.3493
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0198 0.0187 0.0312
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0119 0.0406
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0023 0.0086
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0185 0.0174 0.0595
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0269 0.026 0.0432
Schistosoma mansoni DNA polymerase eta 0.0095 0.0082 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0014 0.0046
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0198 0.0187 0.0187
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0035 0.002 0.0034
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0049 0.0035 0.0058
Schistosoma mansoni apoptosis regulator bax 0.0288 0.0279 0.0279
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0004 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0059 0.0197
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0035 0.0116
Onchocerca volvulus 0.0198 0.0187 0.0631
Loa Loa (eye worm) neuropeptide F receptor 0.0198 0.0187 0.0635
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0014 0.0023
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0009 0.0032
Schistosoma mansoni protein kinase 0.0036 0.0022 0.0022
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0013
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0198 0.0187 0.0187
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Brugia malayi larval opioid receptor 0.0198 0.0187 0.0635
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0008 0.0027
Schistosoma mansoni lamin 0.0081 0.0068 0.0068
Echinococcus granulosus serotonin transporter 0.2894 0.2951 0.4904
Echinococcus granulosus glycogen phosphorylase 0.013 0.0118 0.0197
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0491 0.0488 0.0488
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0071 0.0276
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0014 0.0023
Brugia malayi hypothetical protein 0.0107 0.0095 0.0322
Schistosoma mansoni serine-type protease inhibitor 0.0902 0.0909 0.0909
Brugia malayi AKH receptor 0.0198 0.0187 0.0635
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0013 0.0045
Echinococcus granulosus tyrosine kinase 0.0016 0.0001 0.0002
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0461 0.0457 0.1567
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0233 0.0224 0.0766
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.0359 0.1229
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Brugia malayi Pepsin A precursor 0.0096 0.0083 0.0282
Brugia malayi jmjC domain containing protein 0.0019 0.0004 0.0014
Echinococcus multilocularis g protein coupled receptor 0.0198 0.0187 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Loa Loa (eye worm) cytochrome P450 0.0056 0.0042 0.0143
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0009 0.0032
Schistosoma mansoni alpha-1 adrenergic receptor 0.0198 0.0187 0.0187
Plasmodium vivax aspartyl protease, putative 0.0096 0.0083 0.0282
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0198 0.0187 0.0187
Schistosoma mansoni amine GPCR 0.0198 0.0187 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0045
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0061 0.0207
Echinococcus multilocularis sterol regulatory element binding protein 0.0111 0.0098 0.0163
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0048 0.016
Brugia malayi jmjC domain containing protein 0.0019 0.0004 0.0014
Echinococcus granulosus fmrfamide receptor 0.0198 0.0187 0.0312
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.0242 0.0232 0.0915
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0001 0.0002
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.0203 0.0193 0.066
Echinococcus granulosus netrin receptor unc 5 0.0046 0.0032 0.0053
Schistosoma mansoni DNA helicase recq1 0.0035 0.002 0.002
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0025 0.0082
Brugia malayi G protein-coupled receptor 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0074 0.006 0.0204
Echinococcus granulosus serotonin receptor 0.0198 0.0187 0.0312
Onchocerca volvulus 0.0198 0.0187 0.0631
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0035 0.0021 0.0067
Trypanosoma cruzi metacaspase, putative 0.0035 0.0021 0.0067
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.003 0.0112
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0048 0.0184
Toxoplasma gondii meiotic recombination protein DMC1 family protein 0.0024 0.001 0.0029
Schistosoma mansoni lamin 0.0081 0.0068 0.0068
Trypanosoma cruzi DNA polymerase eta, putative 0.0095 0.0082 0.0278
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0021 0.0079
Trypanosoma brucei chrX additional, unordered contigs 0.002 0.0005 0.0013
Brugia malayi ecdysteroid receptor 0.0028 0.0014 0.0046
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0023 0.0076
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0162 0.0552
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0002 0.0004
Leishmania major metacaspase, putative 0.0035 0.0021 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Echinococcus granulosus flap endonuclease 1 0.0031 0.0017 0.0028
Brugia malayi hypothetical protein 0.0096 0.0083 0.0282
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0056 0.0042 0.0162
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0014 0.0023
Schistosoma mansoni hypothetical protein 0.0222 0.0212 0.0212
Echinococcus granulosus caspase 0.0035 0.0021 0.0034
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.0186 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0021 0.0077
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0045 0.0153
Mycobacterium leprae conserved hypothetical protein 0.0372 0.0367 0.1447
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0029 0.0015 0.0024
Echinococcus multilocularis Smad4 0.0016 0.0001 0.0002
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0016 0.0001 0.0002
Echinococcus granulosus kelch ECH associated protein 1 0.0186 0.0176 0.0292
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Mycobacterium ulcerans beta-lactamase 0.0037 0.0023 0.0086
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0025 0.0041
Brugia malayi MAP kinase sur-1 0.0062 0.0048 0.0162
Chlamydia trachomatis transcriptional repressor NrdR 0.0372 0.0367 0.1255
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.014 0.0129 0.0438
Echinococcus granulosus chromobox protein 1 0.0084 0.0071 0.0118
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0046
Trichomonas vaginalis glutamate synthase, putative 0.0049 0.0035 0.0134
Trypanosoma brucei unspecified product 0.0044 0.003 0.0099
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.0186 0.0632
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0009 0.0032
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0185 0.0174 0.029
Chlamydia trachomatis thioredoxin reductase 0.0049 0.0035 0.0115
Loa Loa (eye worm) hypothetical protein 0.0081 0.0068 0.023
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0198 0.0187 0.0187
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0014 0.0014
Trypanosoma cruzi ribonucleoside-diphosphate reductase small chain, putative 0.014 0.0129 0.0438
Loa Loa (eye worm) hypothetical protein 0.0035 0.002 0.0068
Schistosoma mansoni biogenic amine receptor 0.0198 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.003 0.0112
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0056 0.0042 0.0162
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0022 0.0074
Onchocerca volvulus 0.0048 0.0034 0.011
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit beta 0.014 0.0129 0.0436
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0069 0.0056 0.0056
Trichomonas vaginalis rotamase, putative 0.0039 0.0025 0.0095
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0014 0.0046
Brugia malayi hypothetical protein 0.0016 0.0001 0.0004
Leishmania major DNA polymerase kappa, putative 0.0072 0.0059 0.0197
Loa Loa (eye worm) hypothetical protein 0.0132 0.012 0.0408
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0198 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0032
Schistosoma mansoni tar DNA-binding protein 0.0064 0.005 0.005
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0002
Echinococcus granulosus glycogen phosphorylase 0.013 0.0118 0.0197
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0001 0.0002
Loa Loa (eye worm) glycogen phosphorylase 0.013 0.0118 0.0401
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0011 0.0038
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0076 0.0126
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Echinococcus granulosus Polycystic kidney disease protein 0.0048 0.0034 0.0056
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0761 0.0764 0.2626
Onchocerca volvulus Matrilysin homolog 0.0074 0.006 0.02
Schistosoma mansoni amine GPCR 0.0198 0.0187 0.0187
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0049 0.0035 0.0134
Loa Loa (eye worm) hypothetical protein 0.0491 0.0488 0.1655
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.248 0.2526 1
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0069 0.0056 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0025 0.001 0.0017
Onchocerca volvulus 0.0059 0.0045 0.0148
Mycobacterium tuberculosis Probable oxidoreductase 0.0377 0.0371 0.1466
Brugia malayi MH1 domain containing protein 0.0016 0.0001 0.0005
Loa Loa (eye worm) matrix metalloproteinase 0.0074 0.006 0.0204
Echinococcus granulosus geminin 0.0205 0.0194 0.0323
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0056 0.0042 0.0162
Brugia malayi nuclear receptor NHR-88 0.0028 0.0014 0.0046
Schistosoma mansoni sodium-dependent amino acid transporter 0.0491 0.0488 0.0488
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0004 0.0004
Brugia malayi MH2 domain containing protein 0.0016 0.0001 0.0005
Brugia malayi CHE-14 protein 0.0111 0.0098 0.0332
Loa Loa (eye worm) rad51 0.0024 0.001 0.0033
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0377 0.0371 0.1466
Brugia malayi jmjC domain containing protein 0.0019 0.0004 0.0014
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0198 0.0187 0.0635
Schistosoma mansoni chromobox protein 0.0084 0.0071 0.0071
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0054 0.0041 0.0067
Echinococcus multilocularis integrin beta 2 0.0237 0.0227 0.0378
Schistosoma mansoni carbonic anhydrase-related 0.0233 0.0224 0.0224
Schistosoma mansoni biogenic amine (5HT) receptor 0.0198 0.0187 0.0187
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0008 0.0021
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.0119 0.0467
Echinococcus granulosus kelch ECH associated protein 1 like 0.0186 0.0176 0.0292
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0001 0.0001
Toxoplasma gondii NADPH-glutathione reductase 0.0185 0.0174 0.0595
Echinococcus multilocularis dnaJ subfamily B 0.0838 0.0843 0.1401
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0001 0.0002
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0025 0.001 0.0017
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0049 0.0035 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Leishmania major hypothetical protein, conserved 0.0049 0.0035 0.0116
Loa Loa (eye worm) guanylate kinase 0.0016 0.0001 0.0004
Toxoplasma gondii aspartyl protease ASP1 0.0132 0.012 0.041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0021 0.0079
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0377 0.0371 0.1466
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0049 0.0035 0.0134
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0004 0.0004
Echinococcus multilocularis receptor type guanylyl cyclase 0.0036 0.0022 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0003 0.0006
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.0119 0.0406
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0096 0.0083 0.0282
Onchocerca volvulus 0.0048 0.0034 0.011
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0016 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0009 0.0032
Onchocerca volvulus 0.0491 0.0488 0.1651
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) 0.014 0.0129 0.0504
Trypanosoma brucei protein kinase, putative 0.0062 0.0048 0.016
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0005 0.0008
Echinococcus multilocularis neuropeptide receptor 0.0198 0.0187 0.0312
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.01 0.0341
Schistosoma mansoni hypothetical protein 0.0098 0.0085 0.0085
Brugia malayi hypothetical protein 0.0016 0.0001 0.0004
Trypanosoma brucei metacaspase 0.0035 0.0021 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Plasmodium falciparum ferrodoxin reductase-like protein 0.0049 0.0035 0.0116
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0034 0.0056
Brugia malayi hypothetical protein 0.0096 0.0083 0.0282
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni tar DNA-binding protein 0.0064 0.005 0.005
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.0119 0.0399
Echinococcus granulosus phd:f box containing protein 0.0019 0.0004 0.0007
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0072 0.0059 0.0227
Trypanosoma cruzi metacaspase 5, putative 0.0035 0.0021 0.0067
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0023 0.0086
Brugia malayi hypothetical protein 0.0049 0.0035 0.0117
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0198 0.0187 0.0312
Brugia malayi Doublecortin family protein 0.0048 0.0034 0.0114
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0023 0.0086
Leishmania major trypanothione reductase 0.0533 0.0531 0.1824
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0098 0.0163
Trypanosoma brucei glucosidase, putative 0.0044 0.003 0.0097
Schistosoma mansoni hypothetical protein 0.0222 0.0212 0.0212
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0011 0.0018
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0025 0.001 0.0017
Schistosoma mansoni ap endonuclease 0.0023 0.0008 0.0008
Echinococcus granulosus neuropeptide Y receptor 0.0198 0.0187 0.0312
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0004 0.0009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0009 0.0422
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0025 0.001 0.0017
Echinococcus multilocularis sex peptide receptor 0.0198 0.0187 0.0312
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0126 0.0114 0.0446
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0056 0.0042 0.0162
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.0037 0.0122
Schistosoma mansoni carbonic anhydrase 0.0233 0.0224 0.0224
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0007 0.0021
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0061 0.0061
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0035 0.002 0.0075
Echinococcus granulosus disks large 3 0.0049 0.0035 0.0058
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0004 0.0009
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0044 0.003 0.0049
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0198 0.0187 0.0187
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0095 0.0082 0.0278
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0068 0.023
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0001 0.0002
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0049 0.0035 0.0116
Loa Loa (eye worm) latrophilin receptor protein 2 0.0222 0.0212 0.0718
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.0058 0.0096
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0114 0.0114
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0068 0.023
Echinococcus multilocularis kelch ECH associated protein 1 0.0186 0.0176 0.0292
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0032
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0233 0.0224 0.0759
Echinococcus multilocularis caspase 8 0.0035 0.0021 0.0034
Echinococcus granulosus kelch ECH associated protein 1 like 0.0186 0.0176 0.0292
Plasmodium falciparum metacaspase-like protein 0.0035 0.0021 0.0067
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0198 0.0187 0.0187
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0049 0.0035 0.0134
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain, putative 0.014 0.0129 0.0438
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0009 0.0032
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.009 0.0077 0.026
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) ribonucleotide reductase M2 B 0.014 0.0129 0.0436
Echinococcus granulosus rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0005 0.0013
Echinococcus multilocularis Polycystic kidney disease protein 0.0048 0.0034 0.0056
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0119 0.0467
Echinococcus multilocularis chromobox protein 1 0.0084 0.0071 0.0118
Plasmodium falciparum plasmepsin VII 0.0096 0.0083 0.0282
Echinococcus multilocularis glutamate receptor 2 0.0025 0.001 0.0017
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.2852 0.2908 1
Treponema pallidum thioredoxin reductase (trxB) 0.0049 0.0035 0.0113
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0004
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0037 0.012
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0049 0.0035 0.0058
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0014 0.0023
Onchocerca volvulus 0.0069 0.0056 0.0186
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0016 0.0001 0.0002
Trypanosoma brucei metacaspase MCA2 0.0035 0.0021 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.0238 0.0229 0.0775
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0185 0.0174 0.029
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Onchocerca volvulus 0.0037 0.0023 0.0073
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0014 0.0023
Echinococcus granulosus Glycosyl transferase family 35 0.013 0.0118 0.0197
Entamoeba histolytica glycogen phosphorylase, putative 0.0056 0.0043 0.215
Brugia malayi G-protein coupled receptor 0.0198 0.0187 0.0635
Echinococcus multilocularis protein patched 0.0111 0.0098 0.0163
Giardia lamblia hypothetical protein 0.0017 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0053 0.0039 0.0133
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Echinococcus multilocularis serotonin transporter 0.2894 0.2951 0.4904
Onchocerca volvulus Cell death protein 3 homolog 0.0145 0.0134 0.0449
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0004 0.0007
Loa Loa (eye worm) CYP4Cod1 0.0084 0.0071 0.0239
Plasmodium vivax aspartyl protease, putative 0.0096 0.0083 0.0282
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0049 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0078
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0044 0.003 0.0049
Loa Loa (eye worm) G-protein coupled receptor 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0069 0.0056 0.019
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0035 0.0021 0.007
Brugia malayi carbohydrate phosphorylase 0.013 0.0118 0.0401
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0056 0.0042 0.0162
Brugia malayi Pre-SET motif family protein 0.0037 0.0023 0.0078
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0198 0.0187 0.0187
Brugia malayi MH2 domain containing protein 0.0016 0.0001 0.0005
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0198 0.0187 0.0635
Plasmodium falciparum glutathione reductase 0.0185 0.0174 0.0595
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0034 0.0056
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0053 0.0039 0.013
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Schistosoma mansoni maguk P55 subfamily member 26 0.0016 0.0001 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0005 0.0013
Leishmania major hypothetical protein, conserved 0.0037 0.0023 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0056 0.0042 0.0162
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.5886 0.6017 1
Plasmodium falciparum plasmepsin IV 0.0132 0.012 0.041
Echinococcus granulosus neuropeptides capa receptor 0.0398 0.0393 0.0653
Onchocerca volvulus 0.0037 0.0023 0.0074
Echinococcus granulosus neuropeptide Y receptor 0.0198 0.0187 0.0312
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0001 0.0002
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0016 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0028 0.0094
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0048 0.0079
Brugia malayi RE15519p 0.0198 0.0187 0.0635
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0491 0.0488 0.0488
Trichomonas vaginalis rotamase, putative 0.004 0.0026 0.0098
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0028 0.0013 0.0041
Schistosoma mansoni caspase-7 (C14 family) 0.0145 0.0134 0.0134
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.0083 0.0325
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0268 0.0259 0.0431
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0533 0.0531 0.21
Onchocerca volvulus 0.0198 0.0187 0.0631
Leishmania major hypothetical protein, conserved 0.0053 0.0039 0.013
Brugia malayi Eukaryotic aspartyl protease family protein 0.0096 0.0083 0.0282
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0049 0.0035 0.0116
Echinococcus multilocularis DNA excision repair protein ERCC 1 0.0017 0.0002 0.0003
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0016 0.0001 0.0002
Echinococcus granulosus sodium and chloride dependent glycine 0.0491 0.0488 0.0811
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0001 0.0005
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0491 0.0488 0.0811
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0185 0.0174 0.0595
Schistosoma mansoni glycogen phosphorylase 0.0056 0.0043 0.0043
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0004 0.0014
Onchocerca volvulus 0.0198 0.0187 0.0631
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0054 0.0041 0.0135
Plasmodium falciparum plasmepsin II 0.0132 0.012 0.041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.002 0.0034
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0037 0.0124
Onchocerca volvulus 0.0198 0.0187 0.0631
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.003 0.0097
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0198 0.0187 0.0312
Loa Loa (eye worm) guanylate kinase 0.004 0.0026 0.0089
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0049 0.0035 0.0134
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0046 0.0032 0.0053
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0017 0.0002 0.0003
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0003 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0119 0.6148
Plasmodium vivax ribonucleotide reductase small subunit, putative 0.0048 0.0034 0.0111
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0049 0.0035 0.0134
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0051 0.0173
Echinococcus granulosus neuropeptide receptor A26 0.0198 0.0187 0.0312
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0004 0.0014
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0269 0.026 0.1025
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0119 0.6148
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0107 0.0095 0.037
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0253 0.0244 0.0826
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0004 0.0009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0014 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0034 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0269 0.026 0.0881
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.003 0.0049
Echinococcus granulosus expressed protein 0.004 0.0026 0.0043
Schistosoma mansoni cathepsin D (A01 family) 0.0225 0.0215 0.0215
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0014 0.0046
Brugia malayi hypothetical protein 0.0479 0.0476 0.1612
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0198 0.0187 0.0635
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.0182 0.0714
Plasmodium vivax hypothetical protein, conserved 0.0491 0.0488 0.1675
Echinococcus granulosus 7tm_1 domain containing protein 0.0198 0.0187 0.0312
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0025 0.001 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Echinococcus multilocularis lamin 0.0081 0.0068 0.0113
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0049 0.0035 0.176
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0047 0.0032 0.0107
Echinococcus multilocularis survival motor neuron protein 1 0.0479 0.0476 0.0791
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0198 0.0187 0.0187
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0198 0.0187 0.0635
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0005 0.0013
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0008 0.0027
Brugia malayi Matrixin family protein 0.0074 0.006 0.0204
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0049 0.0035 0.0134
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0006 0.002
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit beta 0.0048 0.0034 0.0128
Schistosoma mansoni intermediate filament proteins 0.0081 0.0068 0.0068
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0096 0.0083 0.0282
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0016 0.0001 0.0004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.2894 0.2951 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0023 0.0038
Schistosoma mansoni hypothetical protein 0.0198 0.0187 0.0187
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0269 0.026 0.089
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0001 0.0002
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0025 0.0082
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0083 0.0282
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0013 0.0045
Schistosoma mansoni neuropeptide receptor 0.0198 0.0187 0.0187
Brugia malayi hypothetical protein 0.0048 0.0034 0.0114
Brugia malayi Cytochrome P450 family protein 0.0084 0.0071 0.0239
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0036 0.0022 0.007
Loa Loa (eye worm) GMP reductase 0.0047 0.0033 0.0113
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0491 0.0488 0.1674
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0056 0.0042 0.0141
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0035 0.0021 0.0077
Loa Loa (eye worm) cytochrome P450 family protein 0.0084 0.0071 0.0239
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Schistosoma mansoni adenoreceptor 0.0198 0.0187 0.0187
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0054 0.0041 0.0135
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0018 0.0003 0.0005
Toxoplasma gondii hypothetical protein 0.0059 0.0045 0.0151
Loa Loa (eye worm) hypothetical protein 0.0096 0.0083 0.0282
Loa Loa (eye worm) hypothetical protein 0.0491 0.0488 0.1655
Brugia malayi Fibronectin type III domain containing protein 0.0037 0.0023 0.0078
Toxoplasma gondii selenide, water dikinase 0.0049 0.0035 0.0116
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0025 0.001 0.0017
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0023 0.0086
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0048 0.0184
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0126 0.0114 0.6514
Schistosoma mansoni tar DNA-binding protein 0.0064 0.005 0.005
Echinococcus granulosus Immunoglobulin 0.0037 0.0023 0.0038
Entamoeba histolytica glycogen phosphorylase, putative 0.013 0.0118 0.6101
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0049 0.0035 0.1953
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0034 0.0056
Onchocerca volvulus 0.0022 0.0007 0.0019
Treponema pallidum ATP-dependent DNA helicase 0.0018 0.0003 0.0004
Onchocerca volvulus 0.0074 0.006 0.02
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0242 0.0232 0.0915
Schistosoma mansoni ribonucleoside-diphosphate reductase small chain 0.014 0.0129 0.0129
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0081 0.0067 0.0067
Echinococcus granulosus bloom syndrome protein 0.005 0.0036 0.0059
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0049 0.0035 0.0058
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0001 0.0005
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.0017 0.0909
Brugia malayi MH2 domain containing protein 0.0238 0.0229 0.0775
Leishmania major guanosine monophosphate reductase 0.0107 0.0095 0.0321
Trypanosoma brucei DNA polymerase eta, putative 0.0095 0.0082 0.0278
Brugia malayi 6-phosphofructokinase 0.0131 0.0119 0.0404
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0048 0.016
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0014 0.0023
Loa Loa (eye worm) pre-B cell enhancing factor 0.1097 0.1109 0.3758
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0107 0.0095 0.037
Echinococcus granulosus intermediate filament protein 0.0081 0.0068 0.0113
Plasmodium falciparum cysteine repeat modular protein 1 0.0053 0.0039 0.013
Toxoplasma gondii kringle domain-containing protein 0.0053 0.0039 0.013
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0023 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0038 0.0127
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0107 0.0095 0.0157
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0014 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Trichomonas vaginalis DNA helicase recq, putative 0.0038 0.0023 0.0088
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0268 0.0259 0.0431
Schistosoma mansoni glutamate synthase 0.0049 0.0035 0.0035
Treponema pallidum NADH oxidase 0.0185 0.0174 0.0585
Giardia lamblia NADH oxidase lateral transfer candidate 0.0185 0.0174 1
Entamoeba histolytica hypothetical protein 0.0107 0.0095 0.4876
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0014 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0013
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0035 0.002 0.0034
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0005 0.0015
Brugia malayi SET domain containing protein 0.0016 0.0002 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0083 0.0282
Mycobacterium leprae Probable lipase LipE 0.0037 0.0023 0.0086
Leishmania major inosine-5-monophosphate dehydrogenase 0.0107 0.0095 0.0321
Echinococcus granulosus peptide allatostatin:somatostatin 0.0198 0.0187 0.0312
Brugia malayi jmjC domain containing protein 0.0019 0.0004 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0014 0.0046
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.2852 0.2908 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0017 0.0054
Brugia malayi beta-lactamase family protein 0.0037 0.0023 0.0078
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0054 0.0041 0.2045
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0054 0.0041 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0056 0.0042 0.0162
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0001 0.0001
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0008 0.0013
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0198 0.0187 0.0312
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Loa Loa (eye worm) programmed cell death 8 0.0049 0.0035 0.0119
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0198 0.0187 0.0635
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0001 0.0002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0001 0.0002
Onchocerca volvulus 0.011 0.0098 0.0327
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0185 0.0174 0.0595
Echinococcus multilocularis glycogen phosphorylase 0.013 0.0118 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0004 0.0011
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.005 0.0171
Echinococcus granulosus DNA excision repair protein ERCC 1 0.0017 0.0002 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0037 0.0141
Loa Loa (eye worm) hypothetical protein 0.0198 0.0187 0.0635
Schistosoma mansoni rotamase 0.004 0.0026 0.0026
Echinococcus multilocularis carbonic anhydrase 0.0233 0.0224 0.0372
Schistosoma mansoni glutamate receptor NMDA 0.0025 0.001 0.001
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.0186 0.031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0198 0.0187 0.0187
Loa Loa (eye worm) lethal(1)discs large-1 tumor suppressor 0.0046 0.0032 0.0108
Trichomonas vaginalis apoptosis inducing factor, putative 0.0049 0.0035 0.0134
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0288 0.0279 0.0464
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.003 0.0097
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0016 0.0001 0.0004
Brugia malayi beta-lactamase family protein 0.0037 0.0023 0.0078
Brugia malayi hypothetical protein 0.0198 0.0187 0.0635
Onchocerca volvulus 0.0049 0.0035 0.0115
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0014 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0198 0.0187 0.0312
Toxoplasma gondii hypothetical protein 0.0491 0.0488 0.1675
Brugia malayi cytochrome P450 0.0056 0.0042 0.0143
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0021 0.1147
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0107 0.0095 0.0321
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0023 0.0038
Echinococcus granulosus apoptotic protease activating factor 1 0.011 0.0098 0.0163
Schistosoma mansoni cpg binding protein 0.0062 0.0048 0.0048

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.5 uM Inhibition of Plasmodium falciparum ENR ChEMBL. 17263522
IC50 (binding) = 20 uM Inhibition of Escherichia coli ENR ChEMBL. 17263522
Ki (binding) = 22 nM Inhibition of Plasmodium falciparum ENR in presence of triclosan ChEMBL. 17263522
Ki (binding) = 0.473 uM Inhibition of Plasmodium falciparum ENR using crotonyl-CoA substrate ChEMBL. 17263522
Ki (binding) = 1.09 uM Inhibition of Plasmodium falciparum ENR using NADH substrate ChEMBL. 17263522
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (binding) = 17.7828 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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