Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
143 records found | Showing page 1 of 6 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
S. mansoni | Smp_155270 | OG5_190385 | hydroxymethylglutaryl-CoA synthase |
S. mansoni | Smp_135260 | OG5_128900 | choline/ethanolaminephosphotransferase 1 |
S. mansoni | Smp_072090.2 | OG5_127857 | [ACP] S-malonyltransferase |
S. mansoni | Smp_049390 | OG5_126801 | pyrroline-5-carboxylate reductase |
S. mansoni | Smp_070780 | OG5_126853 | UDP-glucose 4-epimerase |
S. mansoni | Smp_130430 | OG5_128735 | isopentenyl-diphosphate delta-isomerase |
S. mansoni | Smp_001360 | OG5_126920 | thymidylate kinase |
S. mansoni | Smp_038030 | OG5_128176 | adenylosuccinate lyase |
S. mansoni | Smp_123710 | OG5_127493 | acetyl-CoA carboxylase |
S. mansoni | Smp_013540 | OG5_137498 | tyrosinase precursor |
S. mansoni | Smp_192390 | No group | phenylalanine decarboxylase |
S. mansoni | Smp_195010 | OG5_127526 | hydroxymethylglutaryl-CoA synthase |
S. mansoni | Smp_079840 | OG5_131318 | uroporphyrinogen-III synthase |
S. mansoni | Smp_066200 | OG5_129154 | cytochrome-c oxidase |
S. mansoni | Smp_177230 | No group | cytidylate kinase |
S. mansoni | Smp_128610 | OG5_133034 | cytochrome-c oxidase |
S. mansoni | Smp_129330 | OG5_126757 | acetyl-CoA C-acetyltransferase |
S. mansoni | Smp_168270 | OG5_133897 | nucleoside diphosphate kinase |
S. mansoni | Smp_018500 | OG5_129347 | shikimate-kinase |
S. mansoni | Smp_137330 | OG5_129794 | threonine dehydratase |
S. mansoni | Smp_061870 | OG5_127574 | ubiquinol--cytochrome C reductase |
S. mansoni | Smp_143740 | OG5_127347 | uroporphyrinogen decarboxylase |
S. mansoni | Smp_045260 | OG5_126783 | 5-aminolevulinic acid synthase |
S. mansoni | Smp_144030 | OG5_127441 | phosphatidate cytidylyltransferase |
S. mansoni | Smp_052810 | OG5_127121 | glucose-6-phosphate 1-dehydrogenase |