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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8243 records found | Showing page 2 of 330 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
L. major | LmjF.26.0140 | OG5_127379 | adenine phosphoribosyltransferase | 366 |
L. major | LmjF.21.1080 | OG5_126712 | cell division protein kinase 2,cdc2-related kinase | 366 |
L. major | LmjF.12.0530 | OG5_126980 | glucose-6-phosphate isomerase | 366 |
L. major | LmjF.35.0020 | OG5_126685 | pyruvate kinase | 366 |
L. major | LmjF.16.1540 | OG5_128177 | DNA polymerase I alpha catalytic subunit, putative | 366 |
L. major | LmjF.30.3520 | OG5_126734 | S-adenosylmethionine synthetase | 351 |
L. major | LmjF.21.0240 | OG5_126743 | hexokinase, putative | 351 |
L. major | LmjF.22.1360 | OG5_127590 | farnesyl pyrophosphate synthase | 351 |
L. major | LmjF.18.1080 | OG5_126748 | protein kinase A catalytic subunit | 351 |
L. major | LmjF.31.2940 | OG5_129470 | squalene synthase, putative | 351 |
L. major | LmjF.28.0690 | OG5_126821 | serine/threonine protein phosphatase catalytic subunit, putative | 351 |
L. major | LmjF.06.0370 | OG5_127569 | glutamine synthetase, putative | 351 |
L. major | LmjF.28.2430 | OG5_127061 | vacuolar ATP synthase subunit b, putative | 351 |
L. major | LmjF.07.1030 | OG5_128367 | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 351 |
L. major | LmjF.19.1530 | OG5_126727 | peptidylprolyl isomerase-like protein | 351 |
L. major | LmjF.12.0220 | OG5_127291 | hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative | 351 |
L. major | LmjF.11.1100 | OG5_129288 | lanosterol 14-alpha-demethylase, putative | 351 |
L. major | LmjF.21.1210 | OG5_129576 | thymidine kinase, putative | 351 |
L. major | LmjF.34.0110 | OG5_126762 | adenylate kinase, putative | 351 |
L. major | LmjF.13.1190 | OG5_127011 | adenylosuccinate synthetase, putative | 351 |
L. major | LmjF.20.0110 | OG5_126776 | phosphoglycerate kinase B, cytosolic | 351 |
L. major | LmjF.27.1870 | OG5_134306 | trypanothione synthetase, putative | 341 |
L. major | LmjF.03.0910 | OG5_128875 | inorganic pyrophosphatase, putative | 341 |
L. major | LmjF.08.0100 | OG5_141243 | dual-specificity protein phosphatase, putative | 341 |
L. major | LmjF.36.6650 | OG5_129051 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | 341 |