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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8243 records found | Showing page 1 of 330 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
L. major | LmjF.29.0820 | OG5_127800 | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin ... | 416 |
L. major | LmjF.23.0050 | OG5_126792 | cyclophilin 11, putative | 386 |
L. major | LmjF.05.0350 | OG5_126785 | trypanothione reductase | 386 |
L. major | LmjF.06.0120 | OG5_127452 | cyclophilin 2 | 386 |
L. major | LmjF.25.0910 | OG5_126792 | cyclophilin a | 386 |
L. major | LmjF.18.0270 | OG5_126888 | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 386 |
L. major | LmjF.06.0860 | OG5_127385 | dihydrofolate reductase-thymidylate synthase | 386 |
L. major | LmjF.23.0270 | OG5_133937 | pteridine reductase 1 | 366 |
L. major | LmjF.36.1960 | OG5_127648 | phosphomannomutase, putative | 366 |
L. major | LmjF.24.0850 | OG5_127002 | triosephosphate isomerase | 351 |
L. major | LmjF.12.0220 | OG5_127291 | hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative | 351 |
L. major | LmjF.30.2970 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 351 |
L. major | LmjF.27.1870 | OG5_134306 | trypanothione synthetase, putative | 341 |
L. major | LmjF.06.0560 | OG5_143192 | deoxyuridine triphosphatase, putative,dUTP diphosphatase | 341 |
L. major | LmjF.04.1160 | OG5_127400 | 336 | |
L. major | LmjF.34.1260 | OG5_127218 | mitochondrial DNA polymerase I protein A, putative | 336 |
L. major | LmjF.10.0890 | OG5_128118 | FKBP-type peptidyl-prolyl cis-trans isomerase, putative | 336 |
L. major | LmjF.23.0950 | OG5_127293 | cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 | 336 |
L. major | LmjF.33.1630 | OG5_126792 | cyclophilin 4, putative | 336 |
L. major | LmjF.19.0550 | OG5_126721 | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 336 |
L. major | LmjF.32.1580 | OG5_127555 | phosphomannose isomerase | 336 |
L. major | LmjF.30.0880 | OG5_128398 | adenosine kinase, putative | 336 |
L. major | LmjF.21.0250 | OG5_126743 | hexokinase, putative | 336 |
L. major | LmjF.25.1320 | OG5_127141 | serine/threonine protein phosphatase, putative | 336 |
L. major | LmjF.36.2390 | OG5_129172 | sterol 24-c-methyltransferase, putative | 326 |