Detailed information for compound 1312076

Basic information

Technical information
  • TDR Targets ID: 1312076
  • Name: 10-butyl-4,5-dihydro-[1,2,5]oxadiazolo[3,4-a] carbazole
  • MW: 267.326 | Formula: C16H17N3O
  • H donors: 0 H acceptors: 2 LogP: 3.04 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCn1c2ccccc2c2c1c1nonc1CC2
  • InChi: 1S/C16H17N3O/c1-2-3-10-19-14-7-5-4-6-11(14)12-8-9-13-15(16(12)19)18-20-17-13/h4-7H,2-3,8-10H2,1H3
  • InChiKey: GEQSCUMNVJZVCN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 10-butyl-4,5-dihydrofurazano[3,4-a]carbazole
  • ChemDiv3_001791
  • IDI1_020757
  • MLS000114214
  • SMR000091640

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Bacillus subtilis (strain 168) ATP-dependent Clp protease proteolytic subunit Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus granulosus L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum expressed protein Get druggable targets OG5_129301 All targets in OG5_129301
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus granulosus peptidase Clp S14 family Get druggable targets OG5_127187 All targets in OG5_127187
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K00142 aminoadipate-semialdehyde dehydrogenase [EC1.2.1.31], putative Get druggable targets OG5_129301 All targets in OG5_129301
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K06275 parvin, putative Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Neospora caninum ATP-dependent Clp protease proteolytic subunit, related Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Babesia bovis ATP-dependent Clp protease proteolytic subunit 1, putative Get druggable targets OG5_127187 All targets in OG5_127187
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase Get druggable targets OG5_129301 All targets in OG5_129301
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Onchocerca volvulus Get druggable targets OG5_129301 All targets in OG5_129301
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium hominis proteinx0005 Get druggable targets OG5_129301 All targets in OG5_129301
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Treponema pallidum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K01358 ATP-dependent Clp protease, protease subunit [EC3.4.21.92], putative Get druggable targets OG5_127187 All targets in OG5_127187
Brugia malayi Probable ClpP-like protease Get druggable targets OG5_127187 All targets in OG5_127187
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium yoelii ATP-dependent Clp protease, proteolytic subunit ClpP, putative Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Plasmodium yoelii Clp protease ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.6 %
Onchocerca volvulus 4'-phosphopantetheinyl transferase ffp   224 aa 186 aa 26.3 %
Schistosoma mansoni neuropeptide receptor ATP-dependent Clp protease proteolytic subunit   197 aa 174 aa 20.1 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 35.5 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Entamoeba histolytica hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 198 aa 28.3 %
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 180 aa 36.7 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 ATP-dependent Clp protease proteolytic subunit   197 aa 172 aa 57.0 %
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.1 %
Trichomonas vaginalis conserved hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 197 aa 22.3 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Treponema pallidum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 186 aa 40.3 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Onchocerca volvulus Putative V-type proton ATPase subunit F ATP-dependent Clp protease proteolytic subunit   197 aa 194 aa 54.1 %
Chlamydia trachomatis hypothetical protein ATP-dependent Clp protease proteolytic subunit   197 aa 171 aa 22.8 %
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 36.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Giardia lamblia Cathepsin L-like protease 0.0034 0.0299 0.028
Trypanosoma brucei cysteine peptidase C (CPC) 0.0286 0.3299 1
Onchocerca volvulus 0.0055 0.0557 0.1286
Echinococcus multilocularis calbindin 32 0.0026 0.0212 0.0212
Loa Loa (eye worm) cathepsin B 0.0286 0.3299 0.3299
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.1021 1
Toxoplasma gondii cathepsin CPC2 0.0034 0.0299 0.028
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.006 0.0617 0.0617
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0003 0.0003
Trypanosoma cruzi cysteine protease, putative 0.0048 0.0475 0.0401
Loa Loa (eye worm) hypothetical protein 0.0055 0.0557 0.0557
Echinococcus granulosus GPCR family 2 0.0019 0.0126 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Brugia malayi Cathepsin L-like precursor 0.007 0.0733 0.0733
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0126 0.0126
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0369 0.0507
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0126 0.0126
Schistosoma mansoni cpg binding protein 0.0037 0.0335 0.0335
Trypanosoma cruzi conserved protein 0.0066 0.0682 0.061
Trypanosoma brucei calpain, putative 0.0066 0.0682 0.152
Schistosoma mansoni Mername-AA248 (C02 family) 0.0219 0.2499 0.2499
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0026 0.0212 0.0137
Schistosoma mansoni cathepsin C 0.0034 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.0034 0.0299 0.0299
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.077 0.6811
Echinococcus multilocularis integrin alpha 3 0.0117 0.1286 0.1286
Brugia malayi Inositol-1 0.0036 0.0328 0.0328
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0034 0.0299 0.0606
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.1092 0.1092
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.077 0.077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0048 0.0475 0.085
Trypanosoma brucei hypothetical protein 0.0066 0.0682 0.152
Loa Loa (eye worm) hypothetical protein 0.0084 0.0897 0.0897
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0021 0.0021
Giardia lamblia Cathepsin L precursor 0.0034 0.0299 0.028
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Schistosoma mansoni dopamine-beta-monooxygenase 0.0123 0.1354 0.1354
Loa Loa (eye worm) hypothetical protein 0.0231 0.2638 0.2638
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0034 0.0299 0.0299
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0021 0.0021
Toxoplasma gondii aspartyl protease ASP3 0.0035 0.0311 0.0319
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0369 0.1036
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.077 0.6811
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Echinococcus granulosus cathepsin b 0.0851 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0299 0.028
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.0635 0.7466
Giardia lamblia Cathepsin B precursor 0.0034 0.0299 0.028
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0299 0.0224
Loa Loa (eye worm) hypothetical protein 0.0146 0.1636 0.1636
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Trypanosoma brucei Calpain-like protein 1.1 0.0066 0.0682 0.152
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.0635 0.0635
Entamoeba histolytica cysteine proteinase 2 0.0048 0.0475 0.1735
Schistosoma mansoni hypothetical protein 0.0341 0.3947 0.3947
Trypanosoma brucei antigen, putative 0.0219 0.2499 0.7407
Brugia malayi hypothetical protein 0.0035 0.0311 0.0311
Echinococcus multilocularis calpain 7 (C02 family) 0.0219 0.2499 0.2499
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0475 0.1735
Brugia malayi calpain 5 0.0066 0.0682 0.0682
Echinococcus granulosus cathepsin L cysteine protease 0.0048 0.0475 0.0475
Echinococcus multilocularis centrin 2 0.0026 0.0212 0.0212
Plasmodium vivax unspecified product 0.0034 0.0299 0.0918
Toxoplasma gondii calcium-dependent protein kinase 0.0027 0.0219 0.0021
Loa Loa (eye worm) programmed cell death protein 6 0.0026 0.0212 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0035 0.0311 0.0319
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0021 0.0021
Echinococcus granulosus centrin 2 0.0026 0.0212 0.0212
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0286 0.0649
Leishmania major calpain protease-like protein 0.0066 0.0682 0.152
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.007 0.0733 0.0733
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0607 0.71 0.71
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.1092 0.1092
Plasmodium falciparum plasmepsin IX 0.0035 0.0311 0.0692
Onchocerca volvulus 0.007 0.0733 0.1708
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0021 0.0021
Brugia malayi Integrin alpha pat-2 precursor 0.0152 0.1707 0.1707
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0021 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0066 0.0682 0.061
Schistosoma mansoni hypothetical protein 0.0494 0.576 0.576
Loa Loa (eye worm) fibroinase 0.007 0.0733 0.0733
Echinococcus granulosus cathepsin l1 0.0055 0.0557 0.0557
Loa Loa (eye worm) hypothetical protein 0.007 0.0733 0.0733
Schistosoma mansoni mitochondrial solute carrier 0.0026 0.0212 0.0212
Echinococcus multilocularis calmodulin 0.0026 0.0212 0.0212
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0299 0.028
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0066 0.0682 0.152
Schistosoma mansoni hypothetical protein 0.0019 0.0126 0.0126
Echinococcus granulosus calpain 0.0219 0.2499 0.2499
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.077 0.077
Echinococcus granulosus calpain 5 0.0219 0.2499 0.2499
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Schistosoma mansoni hypothetical protein 0.0041 0.0389 0.0389
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0115 0.1267 0.1267
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Echinococcus multilocularis GPCR, family 2 0.0019 0.0126 0.0126
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Brugia malayi calpain family protein 1 0.0581 0.6788 0.6788
Echinococcus multilocularis cathepsin l cysteine peptidase 0.007 0.0733 0.0733
Schistosoma mansoni cathepsin s 0.0015 0.0076 0.0076
Plasmodium falciparum serine repeat antigen 1 0.0034 0.0299 0.0606
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0284 0.3275 0.3275
Echinococcus granulosus integrin alpha ps 0.0033 0.0289 0.0289
Echinococcus granulosus integrin alpha ps 0.0068 0.0711 0.0711
Echinococcus granulosus neurocalcin 0.0026 0.0212 0.0212
Entamoeba histolytica cysteine protease, putative 0.0034 0.0299 0.0571
Giardia lamblia Hypothetical protein 0.0034 0.0299 0.028
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0299 0.0299
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.077 0.077
Giardia lamblia Cysteine protease 0.0034 0.0299 0.028
Brugia malayi cathepsin L-like precursor 0.0055 0.0557 0.0557
Echinococcus granulosus cathepsin L 0.0034 0.0299 0.0299
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0021 0.0021
Schistosoma mansoni rab 0.0026 0.0212 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0021 0.0021
Entamoeba histolytica cysteine protease, putative 0.0034 0.0299 0.0571
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.1021 0.3899
Echinococcus granulosus calpain A 0.0219 0.2499 0.2499
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0412 0.0412
Trypanosoma cruzi kinesin, putative 0.0153 0.1718 0.1654
Echinococcus multilocularis cpg binding protein 0.0037 0.0335 0.0335
Echinococcus granulosus cathepsin l cysteine peptidase 0.007 0.0733 0.0733
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0146 0.1636 0.1636
Loa Loa (eye worm) hypothetical protein 0.0066 0.0682 0.0682
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0066 0.0682 0.152
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0733 0.0661
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0066 0.0682 0.061
Echinococcus multilocularis neurocalcin 0.0026 0.0212 0.0212
Brugia malayi cathepsin L precursor 0.0034 0.0299 0.0299
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.7407
Schistosoma mansoni hypothetical protein 0.0033 0.0289 0.0289
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.063 0.1355
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0066 0.0682 0.061
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.1021 0.1021
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0733 0.0661
Brugia malayi Eukaryotic aspartyl protease family protein 0.0035 0.0311 0.0311
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0003 0.0003
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.063 0.1355
Trypanosoma cruzi I/6 autoantigen, putative 0.0026 0.0212 0.0137
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0021 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0066 0.0682 0.061
Leishmania major calpain family cysteine protease-like protein 0.0066 0.0682 0.152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Trypanosoma brucei calpain-like protein, putative 0.0219 0.2499 0.7407
Trypanosoma cruzi cysteine proteinase, putative 0.0048 0.0475 0.0401
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0034 0.0299 0.0918
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0026 0.0212 0.0212
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0021 0.0021
Echinococcus multilocularis cathepsin L cysteine protease 0.007 0.0733 0.0733
Echinococcus multilocularis hypothetical protein 0.0219 0.2499 0.2499
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0048 0.0475 0.0475
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0851 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0021 0.0021
Echinococcus multilocularis integrin alpha ps 0.0068 0.0711 0.0711
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0286 0.3299 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0066 0.0682 0.152
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0286 0.3299 0.3248
Loa Loa (eye worm) hypothetical protein 0.0515 0.6007 0.6007
Plasmodium falciparum serine repeat antigen 6 0.0034 0.0299 0.0606
Brugia malayi nuclear hormone receptor 0.001 0.0021 0.0021
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0286 0.052
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Echinococcus granulosus cathepsin l1 0.007 0.0733 0.0733
Echinococcus granulosus dnaJ subfamily B 0.0494 0.576 0.576
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Giardia lamblia Cathepsin L precursor 0.0034 0.0299 0.028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Schistosoma mansoni calmodulin related calcium binding protein 0.0026 0.0212 0.0212
Schistosoma mansoni integrin alpha-ps 0.0036 0.0322 0.0322
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.1639 0.1639
Echinococcus multilocularis cathepsin b 0.0851 1 1
Onchocerca volvulus 0.0034 0.0299 0.0667
Toxoplasma gondii hypothetical protein 0.0066 0.0682 0.152
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Plasmodium falciparum plasmepsin VII 0.0035 0.0311 0.0692
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0286 0.3299 0.3299
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0034 0.0299 0.0918
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0021 0.0021
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0066 0.0682 0.061
Echinococcus granulosus cathepsin L 0.0048 0.0475 0.0475
Leishmania major kinesin, putative 0.0153 0.1718 0.4876
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0722 0.6199
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.063 0.063
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0311 0.0311
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0286 0.3299 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0034 0.0299 0.0918
Brugia malayi Pepsin A precursor 0.0035 0.0311 0.0311
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0733 0.0661
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0581 0.6788 0.6788
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0299 0.0299
Leishmania major hypothetical protein, unknown function 0.0066 0.0682 0.152
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0034 0.0299 0.0918
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Brugia malayi Probable ClpP-like protease 0.0094 0.1021 0.1021
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.576 0.576
Loa Loa (eye worm) calpain 0.0219 0.2499 0.2499
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0021 0.0021
Onchocerca volvulus 0.0026 0.0212 0.046
Onchocerca volvulus 0.007 0.0733 0.1708
Brugia malayi fibroinase precursor 0.0034 0.0299 0.0299
Plasmodium falciparum serine repeat antigen 9 0.0034 0.0299 0.0606
Brugia malayi Calmodulin-like protein 0.0026 0.0212 0.0212
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0299 0.0299
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0034 0.0299 0.0299
Schistosoma mansoni cathepsin B (C01 family) 0.0034 0.0299 0.0299
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Brugia malayi calcium-binding protein 0.0026 0.0212 0.0212
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0235 0.0075
Schistosoma mansoni calpain-2 (C02 family) 0.0066 0.0682 0.0682
Trichomonas vaginalis calpain, putative 0.0066 0.0682 0.152
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0231 0.2638 0.2638
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0066 0.0682 0.152
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0021 0.0021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.7407
Schistosoma mansoni nuclear hormone receptor 0.001 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Loa Loa (eye worm) calmodulin-like protein 0.0026 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0066 0.0682 0.0682
Echinococcus granulosus calbindin 32 0.0026 0.0212 0.0212
Plasmodium vivax vivapain-3 0.0048 0.0475 0.1644
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0026 0.0026
Brugia malayi cathepsin F-like cysteine proteinase 0.0034 0.0299 0.0299
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0299 0.028
Schistosoma mansoni neuronal calcium sensor 0.0026 0.0212 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0021 0.0021
Plasmodium falciparum plasmepsin II 0.0146 0.1636 1
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0299 0.0667
Onchocerca volvulus 0.007 0.0733 0.1708
Toxoplasma gondii preprocathepsin c precursor, putative 0.0034 0.0299 0.028
Entamoeba histolytica cysteine protease, putative 0.0034 0.0299 0.0571
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0026 0.0212 0.0212
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0722 0.0722
Schistosoma mansoni calpain (C02 family) 0.0219 0.2499 0.2499
Echinococcus granulosus cathepsin L cysteine proteinase 0.007 0.0733 0.0733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0412 0.0645
Entamoeba histolytica cysteine proteinase, putative 0.007 0.0733 0.3442
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0021 0.0021
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0048 0.0475 0.0401
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0027 0.0219 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0021 0.0021
Onchocerca volvulus 0.0035 0.0311 0.0696
Loa Loa (eye worm) hypothetical protein 0.0033 0.0289 0.0289
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0328 0.0253
Loa Loa (eye worm) hypothetical protein 0.0015 0.0076 0.0076
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.063 0.1355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0299 0.0299
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0027 0.0219 0.0589
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0021 0.0021
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0028 0.0028
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0126 0.0126
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0299 0.0571
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0299 0.028
Loa Loa (eye worm) hypothetical protein 0.0034 0.0299 0.0299
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0026 0.0212 0.0212
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0328 0.1173
Plasmodium falciparum cysteine proteinase falcipain 3 0.007 0.0733 0.3654
Plasmodium falciparum cysteine proteinase falcipain 2b 0.007 0.0733 0.3654
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0362 0.419 0.419
Entamoeba histolytica cysteine protease, putative 0.0034 0.0299 0.0571
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0034 0.0299 0.0299
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0235 0.0162
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0607 0.71 0.71
Loa Loa (eye worm) hypothetical protein 0.0094 0.1021 0.1021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0299 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0299 0.028
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0062 0.0638 0.0638
Plasmodium falciparum plasmepsin I 0.0146 0.1636 1
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.7407
Schistosoma mansoni neuronal calcium sensor 0.0026 0.0212 0.0212
Giardia lamblia Cysteine protease 0.0034 0.0299 0.028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Loa Loa (eye worm) hypothetical protein 0.0026 0.0212 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.007 0.0733 0.1686
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0328 0.0373
Brugia malayi Cathepsin L-like precursor 0.007 0.0733 0.0733
Plasmodium falciparum plasmepsin III 0.0035 0.0311 0.0692
Onchocerca volvulus 0.01 0.1092 0.2569
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0299 0.0299
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0021 0.0021
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.077 0.1808
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0034 0.0299 0.0918
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0066 0.0682 0.061
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0299 0.028
Plasmodium vivax vivapain-1 0.0048 0.0475 0.1644
Toxoplasma gondii aspartyl protease 0.0035 0.0311 0.0319
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0475 0.085
Schistosoma mansoni thyroid hormone receptor 0.001 0.0021 0.0021
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0299 0.028
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0475 0.1735
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0146 0.1636 0.1636
Echinococcus multilocularis EF hand domain containing family member A2 0.0026 0.0212 0.0212
Brugia malayi Papain family cysteine protease containing protein 0.007 0.0733 0.0733
Onchocerca volvulus 0.007 0.0733 0.1708
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0146 0.1636 0.1636
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0021 0.0021
Brugia malayi aspartic protease BmAsp-1, identical 0.0035 0.0311 0.0311
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0299 0.0299
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0021 0.0021
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0066 0.0682 0.152
Brugia malayi Cathepsin L-like precursor 0.0055 0.0557 0.0557
Plasmodium vivax plasmepsin IV, putative 0.0146 0.1636 0.644
Trypanosoma cruzi centrin, putative 0.0026 0.0212 0.0137
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0231 0.2638 0.2638
Loa Loa (eye worm) hypothetical protein 0.0015 0.0076 0.0076
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.1021 1
Brugia malayi Cathepsin L-like precursor 0.007 0.0733 0.0733
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.063 0.0558
Plasmodium falciparum calpain 0.0066 0.0682 0.3295
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Loa Loa (eye worm) cysteine protease 0.007 0.0733 0.0733
Giardia lamblia Cathepsin L precursor 0.0034 0.0299 0.028
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0021 0.0021
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.063 0.063
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.063 0.063
Echinococcus granulosus calumenin 0.0026 0.0212 0.0212
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0126 0.0126
Trichomonas vaginalis calpain, putative 0.0066 0.0682 0.152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0299 0.028
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Trypanosoma cruzi cysteine proteinase, putative 0.0048 0.0475 0.0401
Plasmodium vivax aspartyl protease, putative 0.0035 0.0311 0.0968
Echinococcus granulosus calmodulin 0.0026 0.0212 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0299 0.028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0055 0.0557 0.0557
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.1021 1
Schistosoma mansoni cathepsin F (C01 family) 0.007 0.0733 0.0733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0557 0.1116
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0733 0.0661
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.2441
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0328 0.0373
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0733 0.0661
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.1639 0.1639
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0066 0.0682 0.061
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0123 0.1354 0.1354
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0126 0.0126
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.0635 0.5085
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.063 0.1355
Giardia lamblia Cathepsin L precursor 0.0034 0.0299 0.028
Echinococcus multilocularis cathepsin L 0.0034 0.0299 0.0299
Onchocerca volvulus 0.0035 0.0311 0.0696
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0021 0.0021
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Toxoplasma gondii cathepsin CPC1 0.0034 0.0299 0.028
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0328 0.0373
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0026 0.0212 0.0137
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0021 0.0021
Entamoeba histolytica calpain large subunit domain III containing protein 0.0153 0.1718 0.9956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0299 0.028
Brugia malayi calpain family protein 1 0.0581 0.6788 0.6788
Plasmodium vivax calpain, putative 0.0219 0.2499 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0021 0.0021
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.077 0.1808
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.1639 0.1639
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Plasmodium falciparum plasmepsin X 0.0035 0.0311 0.0692
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0021 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0219 0.2499 0.2441
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0299 0.0299
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.1021 0.5678
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.1021 0.2619
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0026 0.0212 0.0212
Onchocerca volvulus 0.0026 0.0212 0.046
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0021 0.0021
Echinococcus granulosus calpain A 0.0607 0.71 0.71
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0283 0.0885
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0021 0.0021
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0034 0.0299 0.0606
Onchocerca volvulus 0.007 0.0733 0.1708
Schistosoma mansoni calpain-7 (C02 family) 0.0219 0.2499 0.2499
Echinococcus granulosus programmed cell death protein 0.0026 0.0212 0.0212
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0021 0.0021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0851 1 1
Echinococcus multilocularis cathepsin L 0.0048 0.0475 0.0475
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0722 0.1652
Schistosoma mansoni cpg binding protein 0.0037 0.0335 0.0335
Schistosoma mansoni neuronal calcium sensor 0.0026 0.0212 0.0212
Brugia malayi steroid hormone receptor 0.001 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0299 0.028
Giardia lamblia Cathepsin B precursor 0.0286 0.3299 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0299 0.028
Brugia malayi MH2 domain containing protein 0.0123 0.1361 0.1361
Trichomonas vaginalis hypothetical protein 0.0066 0.0682 0.152
Plasmodium falciparum serine repeat antigen 5 0.0034 0.0299 0.0606
Trypanosoma cruzi caltractin, putative 0.0026 0.0212 0.0137
Echinococcus multilocularis calcium uptake protein 1 0.0026 0.0212 0.0212
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0299 0.0299
Giardia lamblia Cathepsin B precursor 0.0286 0.3299 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0026 0.0212 0.0137
Loa Loa (eye worm) hypothetical protein 0.0041 0.0389 0.0389
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0235 0.0075
Entamoeba histolytica calpain family cysteine protease, putative 0.0066 0.0682 0.3103
Echinococcus multilocularis integrin alpha ps 0.0033 0.0289 0.0289
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.1021 1
Plasmodium falciparum plasmepsin VIII, putative 0.0035 0.0311 0.0692
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.063 0.0558
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Brugia malayi Cathepsin L-like precursor 0.007 0.0733 0.0733
Brugia malayi Cathepsin L-like precursor 0.007 0.0733 0.0733
Schistosoma mansoni centrin 0.0026 0.0212 0.0212
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0219 0.2499 0.2441
Trypanosoma brucei calpain, putative 0.0066 0.0682 0.152
Loa Loa (eye worm) hypothetical protein 0.0035 0.0311 0.0311
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0667 0.0667
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0299 0.0571
Schistosoma mansoni calmodulin 0.0026 0.0212 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.063 0.1355
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.063 0.063
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0026 0.0212 0.0137
Echinococcus multilocularis programmed cell death protein 0.0026 0.0212 0.0212
Entamoeba histolytica protein kinase, putative 0.0154 0.1724 1
Echinococcus multilocularis cysteine protease 0.007 0.0733 0.0733
Loa Loa (eye worm) calpain family protein 1 0.0581 0.6788 0.6788
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0607 0.71 0.71
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.1092 0.1092
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0003 0.0003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.061
Trypanosoma cruzi kinesin, putative 0.0153 0.1718 0.1654
Loa Loa (eye worm) integrin alpha pat-2 0.0235 0.2686 0.2686
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0722 0.6199
Trichomonas vaginalis calpain, putative 0.0066 0.0682 0.152
Brugia malayi Cathepsin L-like precursor 0.0055 0.0557 0.0557
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0299 0.0224
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0066 0.0682 0.152
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0389 0.0389
Brugia malayi calpain 7 0.0219 0.2499 0.2499
Loa Loa (eye worm) papain family cysteine protease containing protein 0.007 0.0733 0.0733
Echinococcus multilocularis calpain 5 0.0219 0.2499 0.2499
Entamoeba histolytica cysteine protease, putative 0.0034 0.0299 0.0571
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0328 0.1173
Schistosoma mansoni centrin-related 0.0026 0.0212 0.0212
Brugia malayi programmed cell death protein 6 0.0026 0.0212 0.0212
Schistosoma mansoni coup transcription factor 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0036 0.0322 0.0322
Echinococcus multilocularis programmed cell death protein 0.0026 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0034 0.0299 0.0299
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0021 0.0021
Trypanosoma cruzi calmodulin, putative 0.0026 0.0212 0.0137
Schistosoma mansoni ef hand domain family member A2 0.0026 0.0212 0.0212
Echinococcus multilocularis neuronal calcium sensor 0.0026 0.0212 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Schistosoma mansoni thyroid hormone receptor 0.001 0.0021 0.0021
Schistosoma mansoni cathepsin D (A01 family) 0.0431 0.5018 0.5018
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0299 0.028
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0066 0.0688 0.154
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.1021 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0066 0.0682 0.152
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Brugia malayi CXXC zinc finger family protein 0.0035 0.0312 0.0312
Loa Loa (eye worm) calpain family protein 1 0.0427 0.4971 0.4971
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0015 0.0076 0.0076
Brugia malayi follicle stimulating hormone receptor 0.0284 0.3275 0.3275
Echinococcus granulosus integrin alpha 3 0.0117 0.1286 0.1286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0055 0.0557 0.0557
Loa Loa (eye worm) hypothetical protein 0.0034 0.0299 0.0299
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Brugia malayi cathepsin F-like cysteine proteinase 0.0015 0.0076 0.0076
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0328 0.0373
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.0635 0.7466
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0328 0.0328
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0219 0.2499 0.2441
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0021 0.0021
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.077 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Toxoplasma gondii cathepsin B 0.0286 0.3299 1
Giardia lamblia Cathepsin L precursor 0.0034 0.0299 0.028
Trypanosoma cruzi I/6 autoantigen, putative 0.0026 0.0212 0.0137
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0055 0.0557 0.0484
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0607 0.71 0.71
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.1361 0.1361
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0033 0.0286 0.0649
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0219 0.2499 0.7407
Onchocerca volvulus 0.0035 0.0312 0.0699
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0328 0.0328
Plasmodium falciparum serine repeat antigen 2 0.0034 0.0299 0.0606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0048 0.0475 0.085
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0299 0.0918
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0034 0.0299 0.0918
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.7407
Brugia malayi EF hand family protein 0.0026 0.0212 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0299 0.028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.2441
Plasmodium vivax vivapain-2 0.007 0.0733 0.2709
Plasmodium vivax aspartyl proteinase, putative 0.0146 0.1636 0.644
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0299 0.0299
Plasmodium falciparum cysteine proteinase falcipain 2a 0.007 0.0733 0.3654
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0615 0.0615
Trypanosoma brucei Calpain-like protein 1.2 0.0066 0.0682 0.152
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.1092 0.1092
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.159 0.159
Schistosoma mansoni cathepsin S (C01 family) 0.0034 0.0299 0.0299
Toxoplasma gondii cathepsin CPL 0.007 0.0733 0.1686
Schistosoma mansoni calpain C (C02 family) 0.0219 0.2499 0.2499
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0299 0.028
Echinococcus granulosus EF HAND 1 calcium binding site 0.0026 0.0212 0.0212
Giardia lamblia Cathepsin L precursor 0.0034 0.0299 0.028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.2441
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0146 0.1636 0.4613
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0412 0.1384
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0076 0.0076
Plasmodium falciparum plasmepsin VI 0.0146 0.1636 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0066 0.0682 0.152
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0034 0.0299 0.028
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0412 0.0645
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0219 0.2499 0.2441
Trypanosoma cruzi calmodulin, putative 0.0026 0.0212 0.0137
Echinococcus multilocularis calpain family protein 1, d 0.0427 0.4971 0.4971
Loa Loa (eye worm) calpain 5 0.0153 0.1718 0.1718
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0557 0.2278
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.1021 0.1021
Giardia lamblia Cathepsin B precursor 0.0286 0.3299 1
Plasmodium falciparum plasmepsin IV 0.0146 0.1636 1
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Plasmodium vivax aspartyl proteinase, putative 0.0035 0.0311 0.0968
Giardia lamblia Cathepsin B precursor 0.0034 0.0299 0.028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0066 0.0682 0.061
Loa Loa (eye worm) acetyltransferase 0.0147 0.1639 0.1639
Brugia malayi nuclear receptor NHR-88 0.001 0.0021 0.0021
Onchocerca volvulus 0.0026 0.0212 0.046
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0235 0.0657
Schistosoma mansoni calpain-7 (C02 family) 0.0219 0.2499 0.2499
Schistosoma mansoni hypothetical protein 0.0019 0.0126 0.0126
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0027 0.0219 0.0144
Plasmodium falciparum serine repeat antigen 7 0.0034 0.0299 0.0606
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.063 0.0558
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0219 0.2499 0.2441
Loa Loa (eye worm) aspartyl protease 6 0.0035 0.0311 0.0311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Trypanosoma brucei kinesin, putative 0.0153 0.1718 0.4876
Trypanosoma brucei cysteine peptidase, putative 0.0066 0.0682 0.152
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0021 0.0021
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0299 0.0918
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0286 0.0867
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0048 0.0475 0.0475
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0851 1 1
Schistosoma mansoni inositol monophosphatase 0.0036 0.0328 0.0328
Schistosoma mansoni inositol monophosphatase 0.0036 0.0328 0.0328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0557 0.1116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.007 0.0733 0.1686
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Echinococcus granulosus calcium uptake protein 1 0.0026 0.0212 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0115 0.1267 0.1267
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.063 0.1355
Plasmodium vivax aspartyl protease, putative 0.0035 0.0311 0.0968
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0328 0.0762
Trypanosoma brucei Calpain-like protein 2 0.0066 0.0682 0.152
Echinococcus multilocularis cysteine protease 0.007 0.0733 0.0733
Schistosoma mansoni peptidylglycine monooxygenase 0.0123 0.1354 0.1354
Schistosoma mansoni hypothetical protein 0.0019 0.0126 0.0126
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.006 0.0615 0.0615
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.063 0.0558
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0021 0.0021
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0034 0.0299 0.0299
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0235 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Entamoeba histolytica cysteine protease, putative 0.007 0.0733 0.3442
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Plasmodium vivax plasmepsin V, putative 0.0035 0.0311 0.0968
Giardia lamblia Cathepsin B precursor 0.0034 0.0299 0.028
Loa Loa (eye worm) EF hand family protein 0.0026 0.0212 0.0212
Entamoeba histolytica cysteine proteinase, putative 0.007 0.0733 0.3442
Leishmania major protein kinase, putative 0.0027 0.0219 0.0021
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0475 0.1735
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0146 0.1636 0.4613
Brugia malayi Papain family cysteine protease containing protein 0.0048 0.0475 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0034 0.0299 0.028
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Schistosoma mansoni integrin alpha 0.0152 0.1707 0.1707
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0328 0.0373
Trypanosoma cruzi centrin, putative 0.0026 0.0212 0.0137
Entamoeba histolytica cysteine protease, putative 0.0034 0.0299 0.0571
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0412 0.0645
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0034 0.0299 0.0606
Loa Loa (eye worm) hypothetical protein 0.0581 0.6788 0.6788
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0021 0.0021
Schistosoma mansoni memapsin-2 (A01 family) 0.0035 0.0311 0.0311
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.063 0.1355
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Brugia malayi EF hand family protein 0.0026 0.0212 0.0212
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0299 0.0299
Echinococcus multilocularis integrin alpha ps 0.0068 0.0711 0.0711
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.063 0.1355
Leishmania major cysteine peptidase A (CPA) 0.007 0.0733 0.1686
Echinococcus granulosus cathepsin b 0.0851 1 1
Plasmodium falciparum serine repeat antigen 4 0.0034 0.0299 0.0606
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Loa Loa (eye worm) ctsf protein 0.007 0.0733 0.0733
Loa Loa (eye worm) inositol-1 0.0036 0.0328 0.0328
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0851 1 1
Loa Loa (eye worm) hypothetical protein 0.0427 0.4971 0.4971
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0722 0.0722
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.0635 0.0635
Schistosoma mansoni hypothetical protein 0.0026 0.0212 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0475 0.085
Plasmodium vivax unspecified product 0.0048 0.0475 0.1644
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.077 0.6811
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0682 0.152
Plasmodium falciparum serine repeat antigen 3 0.0034 0.0299 0.0606
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0812 0.9539 0.9539
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0312 0.0312
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.063 0.1355
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0034 0.0299 0.028
Schistosoma mansoni hypothetical protein 0.0341 0.3947 0.3947
Trypanosoma brucei Calpain-like protein CALP1.3 0.0066 0.0682 0.152
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0231 0.2638 0.2638
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0034 0.0299 0.028
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0235 0.0075
Plasmodium falciparum serine repeat antigen 8 0.0034 0.0299 0.0606
Echinococcus granulosus cpg binding protein 0.0037 0.0335 0.0335
Echinococcus granulosus EF hand domain containing family member A2 0.0026 0.0212 0.0212
Giardia lamblia Cysteine protease 0.0034 0.0299 0.028
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0066 0.0682 0.061
Brugia malayi calpain D 0.0066 0.0682 0.0682
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Echinococcus granulosus EF hand domain containing family member A2 0.0026 0.0212 0.0212
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0212 0.0561
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0851 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0126
Echinococcus multilocularis calpain 0.0219 0.2499 0.2499
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0299 0.028
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0475 0.1735
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.0723 0.1653
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0299 0.028
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0028 0.0028
Onchocerca volvulus Cathepsin L homolog 0.007 0.0733 0.1708
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0615 0.0615
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0722 0.9102
Loa Loa (eye worm) hypothetical protein 0.0034 0.0299 0.0299
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0066 0.0682 0.152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Loa Loa (eye worm) hypothetical protein 0.012 0.1319 0.1319
Schistosoma mansoni calmodulin 0.0026 0.0212 0.0212
Plasmodium vivax vivapain-2 0.007 0.0733 0.2709
Giardia lamblia Cysteine protease 0.0034 0.0299 0.028
Brugia malayi MAP kinase sur-1 0.0062 0.063 0.063
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0034 0.0299 0.0299
Trypanosoma brucei protein kinase, putative 0.0062 0.063 0.1355
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.063 0.063
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0021 0.0021
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0048 0.0475 0.0475
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Giardia lamblia Cathepsin B precursor 0.0034 0.0299 0.028
Brugia malayi ecdysteroid receptor 0.001 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0019 0.0126 0.0126
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.007 0.0733 0.1686
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.1021 0.2619
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0066 0.0682 0.152
Echinococcus multilocularis EF hand domain containing family member A2 0.0026 0.0212 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0021 0.0021
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0003 0.0003
Trypanosoma brucei calpain-like protein, putative 0.0219 0.2499 0.7407
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0034 0.0299 0.0918
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0722 0.0722
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0299 0.0918
Echinococcus multilocularis cathepsin L cysteine protease 0.007 0.0733 0.0733
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0034 0.0299 0.0918
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Trypanosoma cruzi calmodulin, putative 0.0026 0.0212 0.0137
Giardia lamblia Cathepsin L-like protease 0.0034 0.0299 0.028
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0066 0.0682 0.061
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0026 0.0212 0.0212
Loa Loa (eye worm) calpain D 0.0066 0.0682 0.0682
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0146 0.1636 0.1636
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0126 0.0126
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Loa Loa (eye worm) hypothetical protein 0.0123 0.1354 0.1354
Entamoeba histolytica cysteine proteinase 1, putative 0.0048 0.0475 0.1735
Brugia malayi Cathepsin L-like precursor 0.0015 0.0076 0.0076
Trypanosoma brucei calpain-like protein, putative 0.0219 0.2499 0.7407
Plasmodium vivax aspartyl protease, putative 0.0035 0.0311 0.0968
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0557 0.0557
Schistosoma mansoni integrin alpha-ps 0.0068 0.0711 0.0711
Echinococcus granulosus neuronal calcium sensor 0.0026 0.0212 0.0212
Brugia malayi Cathepsin L-like precursor 0.007 0.0733 0.0733
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.1021 1
Echinococcus multilocularis calmodulin 0.0026 0.0212 0.0212
Brugia malayi calpain 5 0.0153 0.1718 0.1718
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0412 0.0645
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0615 0.0615
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0021 0.0021
Plasmodium falciparum cysteine proteinase falcipain 1 0.0048 0.0475 0.1842
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Onchocerca volvulus 0.007 0.0733 0.1708
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0299 0.0918
Schistosoma mansoni cathepsin D (A01 family) 0.0431 0.5018 0.5018
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0231 0.2638 0.2638
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0328 0.0253
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0035 0.0311 0.0311
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.1361 0.1361
Plasmodium falciparum plasmepsin V 0.0035 0.0311 0.0692
Trypanosoma cruzi centrin-3 0.0026 0.0212 0.0137
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0035 0.0311 0.0311
Onchocerca volvulus 0.007 0.0733 0.1708
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0773 0.0773
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0299 0.0299
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.063 0.063
Loa Loa (eye worm) hypothetical protein 0.0851 1 1
Echinococcus granulosus FTZ F1 alpha 0.001 0.0021 0.0021
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0369 0.11
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0076 0.0076
Schistosoma mansoni cpg binding protein 0.0035 0.0312 0.0312
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0066 0.0682 0.152
Echinococcus granulosus geminin 0.0341 0.3947 0.3947
Trypanosoma brucei calpain-like protein, putative 0.0219 0.2499 0.7407
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0034 0.0299 0.0299
Entamoeba histolytica cysteine protease, putative 0.0048 0.0475 0.1735
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0283 0.0603
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.1021 1
Onchocerca volvulus 0.0362 0.419 1
Schistosoma mansoni neuronal calcium sensor 0.0026 0.0212 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0733 0.1686
Onchocerca volvulus Cathepsin F homolog 0.007 0.0733 0.1708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.007 0.0733 0.1686
Brugia malayi Papain family cysteine protease containing protein 0.0048 0.0475 0.0475
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0026 0.0212 0.0212
Brugia malayi hypothetical protein 0.0035 0.0311 0.0311
Giardia lamblia Cathepsin B precursor 0.0034 0.0299 0.028
Leishmania major cathepsin L-like protease 0.007 0.0733 0.1686
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0219 0.2499 0.2441
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0722 0.0722
Echinococcus multilocularis cathepsin l cysteine peptidase 0.007 0.0733 0.0733
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.1021 0.1021
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0021 0.0021
Echinococcus multilocularis cathepsin b 0.0851 1 1
Schistosoma mansoni hypothetical protein 0.0026 0.0212 0.0212
Giardia lamblia Encystation-specific protease 0.0034 0.0299 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0299 0.028
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0328 0.0373
Schistosoma mansoni reticulocalbin 0.0026 0.0212 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.0048 0.0475 0.0401
Echinococcus multilocularis calumenin 0.0026 0.0212 0.0212
Entamoeba histolytica hypothetical protein 0.0028 0.0235 0.0153
Echinococcus multilocularis calpain A 0.0607 0.71 0.71
Onchocerca volvulus Cathepsin L homolog 0.007 0.0733 0.1708
Toxoplasma gondii aspartyl protease ASP1 0.0146 0.1636 0.4613
Brugia malayi aspartic protease BmAsp-2, identical 0.0035 0.0311 0.0311
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0027 0.0219 0.0021
Toxoplasma gondii hypothetical protein 0.0033 0.0286 0.024
Schistosoma mansoni reticulocalbin 0.0026 0.0212 0.0212
Plasmodium vivax centrin-1, putative 0.0026 0.0212 0.0561
Loa Loa (eye worm) hypothetical protein 0.01 0.1092 0.1092
Entamoeba histolytica hypothetical protein 0.0034 0.0299 0.0571
Echinococcus granulosus calpain 7 C02 family 0.0219 0.2499 0.2499
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.077 0.077
Brugia malayi Cathepsin L-like cysteine proteinase 0.0055 0.0557 0.0557
Echinococcus multilocularis geminin 0.0341 0.3947 0.3947
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0219 0.2499 0.2441
Echinococcus granulosus cysteine protease 0.0048 0.0475 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0034 0.0299 0.028
Brugia malayi cathepsin L-like cysteine proteinase 0.0034 0.0299 0.0299
Giardia lamblia Hypothetical protein 0.0034 0.0299 0.028
Schistosoma mansoni cathepsin F (C01 family) 0.007 0.0733 0.0733

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 50 um PUBCHEM_BIOASSAY: BAP1 Enzyme inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 436 (Primary screen preceding this dose response confirmation assay.)] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.