Detailed information for compound 222165

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 396.524 | Formula: C27H28N2O
  • H donors: 0 H acceptors: 0 LogP: 5.52 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)OCCCN1CCc2c(C1)c1ccccc1n2Cc1ccccc1
  • InChi: 1S/C27H28N2O/c1-3-10-22(11-4-1)20-29-26-15-8-7-14-24(26)25-21-28(18-16-27(25)29)17-9-19-30-23-12-5-2-6-13-23/h1-8,10-15H,9,16-21H2
  • InChiKey: YOTAKMDVJZTBPZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus 5-hydroxytryptamine (serotonin) receptor 5A Starlite/ChEMBL References
Rattus norvegicus Serotonin 2a (5-HT2a) receptor Starlite/ChEMBL References
Rattus norvegicus Serotonin 2c (5-HT2c) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Serotonin receptor Get druggable targets OG5_135430 All targets in OG5_135430
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis g protein coupled receptor Serotonin 2a (5-HT2a) receptor   471 aa 417 aa 20.6 %
Echinococcus multilocularis neuropeptides capa receptor Serotonin 2c (5-HT2c) receptor   460 aa 408 aa 20.8 %
Echinococcus granulosus g protein coupled receptor Serotonin 2a (5-HT2a) receptor   471 aa 416 aa 19.2 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Serotonin 2c (5-HT2c) receptor   460 aa 405 aa 31.1 %
Echinococcus granulosus g protein coupled receptor Serotonin 2a (5-HT2a) receptor   471 aa 408 aa 21.8 %
Onchocerca volvulus Ubiquinol-cytochrome-c reductase complex assembly factor 1 homolog Serotonin 2a (5-HT2a) receptor   471 aa 435 aa 23.0 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Serotonin 2a (5-HT2a) receptor   471 aa 422 aa 27.5 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Serotonin 2a (5-HT2a) receptor   471 aa 405 aa 25.4 %
Echinococcus multilocularis g protein coupled receptor Serotonin 2a (5-HT2a) receptor   471 aa 462 aa 21.2 %
Loa Loa (eye worm) hypothetical protein Serotonin 2c (5-HT2c) receptor   460 aa 417 aa 21.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.3156
Leishmania major phospholipase c-like protein 0.0032 0.0013 0.0042
Echinococcus multilocularis cathepsin L cysteine protease 0.009 0.0399 0.0386
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0044 0.0094 0.0506
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0054 0.016 0.0461
Giardia lamblia Cysteine protease 0.0054 0.016 0.0461
Loa Loa (eye worm) calmodulin-like protein 0.0032 0.0013 0.001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0054 0.016 0.0157
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0223 0.0221
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.012
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0223 0.021
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0069 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0044 0.0094 0.0091
Entamoeba histolytica calmodulin, putative 0.0044 0.0094 0.0328
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0055 0.0168 0.0168
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0054 0.016 0.0601
Schistosoma mansoni gamma-secretase subunit aph-1 0.0753 0.4796 0.4796
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0054 0.016 0.0601
Plasmodium falciparum cysteine repeat modular protein 1 0.0034 0.0028 0.0061
Echinococcus granulosus Calcium binding protein 0.0044 0.0094 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0502 0.1531
Echinococcus granulosus calpain 0.0182 0.1011 0.0999
Loa Loa (eye worm) hypothetical protein 0.0075 0.0302 0.0299
Schistosoma mansoni mitochondrial solute carrier 0.0032 0.0013 0.0013
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0055 0.0165 0.0516
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0895 0.2765
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0055 0.0165 0.0165
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0052 0.012
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0682 0.4325 0.4717
Echinococcus granulosus neuropeptide s receptor 0.0484 0.3013 0.3004
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.0488 0.0476
Giardia lamblia Calmodulin 0.0044 0.0094 0.0252
Giardia lamblia Cathepsin L precursor 0.0054 0.016 0.0461
Loa Loa (eye worm) hypothetical protein 0.0125 0.0629 0.0626
Schistosoma mansoni hypothetical protein 0.0041 0.0073 0.0073
Echinococcus granulosus FK506 binding protein 2 0.0055 0.0168 0.0154
Loa Loa (eye worm) hypothetical protein 0.0107 0.051 0.0507
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0502 0.0489
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0116 0.0575 0.0562
Brugia malayi 6-phosphofructokinase 0.0105 0.0502 0.0489
Brugia malayi Ets-domain containing protein 0.0075 0.0302 0.0289
Mycobacterium tuberculosis Probable lipase LipE 0.0107 0.051 0.0388
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.0488 0.0488
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.04 0.2458 0.2448
Schistosoma mansoni calpain-2 (C02 family) 0.0055 0.0165 0.0165
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.1011
Brugia malayi CHE-14 protein 0.0042 0.0083 0.007
Brugia malayi 6-phosphofructokinase 0.0105 0.0502 0.0489
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.1395 0.1392
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0738 0.0726
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0052 0.0161
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0041 0.0073 0.0073
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0083 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Echinococcus granulosus cathepsin L cysteine proteinase 0.009 0.0399 0.0386
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0226 0.1298 0.1298
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0075 0.0302 0.0302
Schistosoma mansoni alpha-glucosidase 0.0146 0.0771 0.0771
Entamoeba histolytica cysteine protease, putative 0.0054 0.016 0.0601
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.0488 0.0476
Onchocerca volvulus 0.009 0.0399 0.2205
Schistosoma mansoni calmodulin 0.0032 0.0013 0.0013
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Mycobacterium tuberculosis Conserved protein 0.0107 0.051 0.0388
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0488 0.0488
Echinococcus multilocularis cathepsin L cysteine protease 0.009 0.0399 0.0386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0302 0.0905
Echinococcus granulosus lysosomal alpha glucosidase 0.017 0.0927 0.0915
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0502 0.0379
Schistosoma mansoni hypothetical protein 0.0125 0.0629 0.0629
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0052 0.012
Echinococcus granulosus calcyphosin protein 0.0044 0.0094 0.008
Brugia malayi Cathepsin L-like precursor 0.009 0.0399 0.0386
Leishmania major calmodulin, putative 0.0032 0.0013 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0513 0.3203 1
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Brugia malayi cathepsin L precursor 0.0054 0.016 0.0147
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Loa Loa (eye worm) hypothetical protein 0.0052 0.0146 0.0143
Loa Loa (eye worm) cathepsin B 0.0513 0.3203 0.3202
Entamoeba histolytica hypothetical protein 0.0144 0.0755 0.3035
Brugia malayi Serotonin receptor 0.0585 0.368 0.3671
Entamoeba histolytica protein kinase, putative 0.0128 0.0654 0.262
Echinococcus multilocularis geminin 0.1015 0.6535 0.653
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0895 0.2765
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0055 0.0168 0.0483
Schistosoma mansoni neuronal calcium sensor 0.0032 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.016 0.0461
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0078 0.0202
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0055 0.0165 0.0165
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0078 0.0417
Trichomonas vaginalis fk506 binding protein, putative 0.0055 0.0168 0.0483
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0488 0.1489
Plasmodium vivax vivapain-2 0.009 0.0399 0.1576
Loa Loa (eye worm) calpain family protein 1 0.0356 0.2162 0.2159
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0055 0.0168 0.0154
Brugia malayi cathepsin L-like cysteine proteinase 0.0054 0.016 0.0147
Echinococcus multilocularis tissue type plasminogen activator 0.0034 0.0028 0.0015
Entamoeba histolytica cysteine proteinase 1, putative 0.0069 0.0257 0.0997
Leishmania major hypothetical protein, conserved 0.0032 0.0013 0.0042
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0291 0.1134
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.04 0.2458 0.2448
Giardia lamblia Cathepsin B precursor 0.0513 0.3203 1
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1468 0.4561
Echinococcus granulosus calpain A 0.0182 0.1011 0.0999
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.0488 0.0476
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0093 0.0419 0.232
Onchocerca volvulus 0.009 0.0399 0.2205
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0074 0.0291 0.0291
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0057 0.0044
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0107 0.051 0.0388
Leishmania major calmodulin, putative 0.0032 0.0013 0.0042
Onchocerca volvulus Cathepsin L homolog 0.009 0.0399 0.2205
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.04 0.2458 0.7664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Giardia lamblia Cysteine protease 0.0054 0.016 0.0461
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0399 0.0399
Plasmodium vivax vivapain-3 0.0069 0.0257 0.0997
Schistosoma mansoni cathepsin F (C01 family) 0.0075 0.0302 0.0302
Schistosoma mansoni fk506 binding protein 0.0055 0.0168 0.0168
Trypanosoma brucei calmodulin, putative 0.0032 0.0013 0.0042
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0054 0.016 0.0157
Brugia malayi PHD-finger family protein 0.0049 0.0124 0.0111
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0054 0.016 0.0601
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0223 0.0223
Trichomonas vaginalis calpain, putative 0.0055 0.0165 0.0477
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0044 0.0094 0.0081
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0182 0.1011 0.1011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0428 0.2644 0.2642
Echinococcus multilocularis protein dispatched 1 0.0048 0.0123 0.011
Plasmodium falciparum calpain 0.0055 0.0165 0.0622
Schistosoma mansoni hypothetical protein 0.0144 0.0755 0.0755
Trypanosoma brucei protein kinase, putative 0.0103 0.0488 0.1524
Brugia malayi RasGEF domain containing protein 0.0044 0.0094 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1468 0.4561
Brugia malayi Cathepsin L-like precursor 0.0075 0.0302 0.0289
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0954 0.2949
Brugia malayi follicle stimulating hormone receptor 0.0253 0.1483 0.1471
Schistosoma mansoni hypothetical protein 0.0055 0.0165 0.0165
Giardia lamblia Hypothetical protein 0.0054 0.016 0.0461
Brugia malayi Cathepsin L-like precursor 0.009 0.0399 0.0386
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.009 0.0399 0.1208
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0057 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0057 0.0138
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0074 0.0291 0.0278
Echinococcus multilocularis programmed cell death protein 6 0.0044 0.0094 0.008
Mycobacterium tuberculosis Conserved protein 0.0107 0.051 0.0388
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0055 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.012 0.06 0.0597
Brugia malayi calpain family protein 1 0.0483 0.3007 0.2998
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0055 0.0165 0.0165
Echinococcus granulosus neuropeptide receptor A26 0.0484 0.3013 0.3004
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0267 0.0254
Onchocerca volvulus Cathepsin L homolog 0.009 0.0399 0.2205
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0055 0.0168 0.0154
Plasmodium falciparum serine repeat antigen 2 0.0054 0.016 0.0601
Brugia malayi TAR-binding protein 0.0064 0.0223 0.021
Loa Loa (eye worm) hypothetical protein 0.024 0.1392 0.139
Trypanosoma cruzi cysteine protease, putative 0.0069 0.0257 0.0257
Schistosoma mansoni hypothetical protein 0.0125 0.0629 0.0629
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0078 0.0202
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1538 1 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0502 0.1458
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.016 0.0461
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0054 0.016 0.0147
Schistosoma mansoni hypothetical protein 0.1015 0.6535 0.6535
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0895 0.2765
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0074 0.0291 0.014
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0157
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.3156
Schistosoma mansoni neuronal calcium sensor 0.0032 0.0013 0.0013
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Echinococcus granulosus programmed cell death protein 0.0076 0.0305 0.0292
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0302 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.016 0.0461
Schistosoma mansoni chromobox protein 0.0069 0.0259 0.0259
Trypanosoma brucei Aph-1 protein, putative 0.0293 0.1748 0.5456
Leishmania major protein kinase, putative 0.0033 0.002 0.0061
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0488 0.0488
Plasmodium falciparum cysteine proteinase falcipain 3 0.009 0.0399 0.1576
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0055 0.0168 0.0631
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.04 0.2458 0.2458
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0055 0.0165 0.0477
Onchocerca volvulus 0.0107 0.051 0.2825
Brugia malayi chromobox protein homolog 3 0.0039 0.0058 0.0045
Loa Loa (eye worm) myosin Light Chain family member 0.0044 0.0094 0.0091
Leishmania major fk506-binding protein 1-like protein 0.04 0.2458 0.7673
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0106 0.0505 0.0492
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0502 0.0502
Trypanosoma brucei calpain, putative 0.0055 0.0165 0.0516
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0055 0.0168 0.0154
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0125 0.0629 0.0616
Trypanosoma brucei Component of motile flagella 41 0.0032 0.0013 0.0042
Schistosoma mansoni patched 1 0.0042 0.0083 0.0083
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0515 0.3218 0.3218
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Brugia malayi Cytochrome P450 family protein 0.0047 0.0117 0.0104
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0259 0.077
Giardia lamblia Cathepsin B precursor 0.0513 0.3203 1
Trichomonas vaginalis esterase, putative 0.0107 0.051 0.1557
Trichomonas vaginalis calcium binding protein, putative 0.0076 0.0305 0.0914
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0502 0.0499
Onchocerca volvulus 0.0054 0.016 0.0877
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0223 0.0223
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0467 0.0467
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0057 0.0044
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0502 0.1566
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Loa Loa (eye worm) hypothetical protein 0.0055 0.0168 0.0165
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.002 0.0025
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0117 0.0114
Echinococcus granulosus SAM and MBT domain containing protein 0.0093 0.0419 0.0407
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1468 0.4561
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0044 0.0094 0.0328
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0502 0.0379
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.016 0.0461
Loa Loa (eye worm) calpain 5 0.0127 0.0648 0.0645
Trypanosoma cruzi centrin-3 0.0076 0.0305 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0094 0.0252
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Brugia malayi calpain D 0.0055 0.0165 0.0152
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.0488 0.1524
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0125 0.0629 0.0616
Plasmodium falciparum cysteine proteinase falcipain 1 0.0069 0.0257 0.0997
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.016 0.0461
Plasmodium vivax unspecified product 0.0054 0.016 0.0601
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Toxoplasma gondii hypothetical protein 0.0055 0.0165 0.0477
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0107 0.051 0.0497
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Schistosoma mansoni cathepsin C 0.0054 0.016 0.016
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0055 0.0168 0.0154
Entamoeba histolytica cysteine protease, putative 0.0054 0.016 0.0601
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.016 0.0461
Leishmania major kinesin, putative 0.0127 0.0648 0.2021
Entamoeba histolytica cysteine proteinase, putative 0.0069 0.0257 0.0997
Echinococcus granulosus beta LACTamase domain containing family member 0.0107 0.051 0.0497
Echinococcus multilocularis calpain 7 (C02 family) 0.0182 0.1011 0.0999
Loa Loa (eye worm) hypothetical protein 0.0394 0.2416 0.2414
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0168 0.0483
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0055 0.0165 0.0516
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0055 0.0168 0.0523
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0631
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0054 0.016 0.0601
Toxoplasma gondii cathepsin CPC1 0.0054 0.016 0.0461
Toxoplasma gondii calmodulin CAM2 0.0044 0.0094 0.0252
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0055 0.0168 0.0483
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.016 0.0461
Brugia malayi beta-lactamase 0.0107 0.051 0.0497
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1468 0.4561
Echinococcus multilocularis neuropeptide receptor A26 0.0484 0.3013 0.3004
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0502 0.1997
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.028 0.1661 0.1661
Giardia lamblia Cysteine protease 0.0054 0.016 0.0461
Echinococcus multilocularis cathepsin l cysteine peptidase 0.009 0.0399 0.0386
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.1011
Loa Loa (eye worm) EF hand family protein 0.0032 0.0013 0.001
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0054 0.016 0.0461
Onchocerca volvulus 0.0107 0.051 0.2825
Loa Loa (eye worm) hypothetical protein 0.0269 0.1589 0.1586
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0107 0.051 0.0388
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0488 0.1489
Echinococcus granulosus methyl CpG binding domain protein 2 0.0033 0.0023 0.0009
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.04 0.2458 0.2448
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0055 0.0165 0.0477
Loa Loa (eye worm) hypothetical protein 0.0033 0.0023 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.051 0.051
Loa Loa (eye worm) ctsf protein 0.009 0.0399 0.0396
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.1468 0.1457
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0895 0.2765
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.1468 0.1466
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0253 0.1483 0.148
Schistosoma mansoni zinc finger protein 0.0038 0.0055 0.0055
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.04 0.2458 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0457 0.0454
Entamoeba histolytica calpain large subunit domain III containing protein 0.0127 0.0648 0.2594
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0032 0.0013 0.0013
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0057 0.018
Echinococcus multilocularis cathepsin L 0.0069 0.0257 0.0244
Brugia malayi latrophilin 2 splice variant baaae 0.0269 0.1589 0.1577
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.016 0.0461
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Leishmania major i/6 autoantigen-like protein 0.0032 0.0013 0.0042
Echinococcus multilocularis protein patched 0.0042 0.0083 0.007
Trypanosoma brucei calpain-like protein, putative 0.0182 0.1011 0.3156
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0502 0.9755
Echinococcus multilocularis Calcium binding protein 0.0044 0.0094 0.008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0055 0.0168 0.0168
Echinococcus granulosus cathepsin l1 0.0075 0.0302 0.0289
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Echinococcus multilocularis SAM and MBT domain containing protein 0.0093 0.0419 0.0407
Trypanosoma brucei centrin, putative 0.0032 0.0013 0.0042
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0054 0.016 0.0601
Schistosoma mansoni hypothetical protein 0.0125 0.0629 0.0629
Entamoeba histolytica grainin 2 0.0076 0.0305 0.1193
Entamoeba histolytica cysteine proteinase, putative 0.0075 0.0302 0.1181
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Onchocerca volvulus 0.009 0.0399 0.2205
Giardia lamblia Cathepsin L precursor 0.0054 0.016 0.0461
Trypanosoma brucei hypothetical protein, conserved 0.0107 0.051 0.1592
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0107 0.051 0.0388
Schistosoma mansoni centrin 0.0032 0.0013 0.0013
Loa Loa (eye worm) TK/ROR protein kinase 0.0034 0.0028 0.0025
Treponema pallidum exodeoxyribonuclease (exoA) 0.0074 0.0291 0.0537
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.04 0.2458 0.7664
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0223 0.021
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0106 0.0505 0.0492
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0345 0.2093 0.2082
Echinococcus multilocularis programmed cell death protein 0.0076 0.0305 0.0292
Trichomonas vaginalis caltractin, putative 0.0044 0.0094 0.0252
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0394 0.2416 0.2414
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0055 0.0165 0.0477
Echinococcus multilocularis cysteine protease 0.009 0.0399 0.0386
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0399 0.0399
Echinococcus granulosus histone acetyltransferase MYST2 0.0106 0.0505 0.0492
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.0488 0.1524
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0032 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0055
Trypanosoma cruzi Aph-1 protein, putative 0.0293 0.1748 0.1748
Loa Loa (eye worm) beta-lactamase 0.0107 0.051 0.0507
Schistosoma mansoni hypothetical protein 0.0049 0.0126 0.0126
Brugia malayi Cathepsin L-like cysteine proteinase 0.0075 0.0302 0.0289
Brugia malayi gamma-secretase subunit aph-1 0.0753 0.4796 0.4789
Leishmania major hypothetical protein, conserved 0.0032 0.0013 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Echinococcus multilocularis expressed conserved protein 0.0093 0.0417 0.0404
Trypanosoma brucei Calpain-like protein CALP1.3 0.0055 0.0165 0.0516
Mycobacterium ulcerans hypothetical protein 0.0107 0.051 0.0388
Echinococcus granulosus Myosin regulatory light chain 0.0044 0.0094 0.008
Brugia malayi mbt repeat family protein 0.0093 0.0419 0.0407
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.3156
Brugia malayi beta-lactamase family protein 0.0107 0.051 0.0497
Echinococcus multilocularis programmed cell death protein 0.0076 0.0305 0.0292
Schistosoma mansoni hypothetical protein 0.1015 0.6535 0.6535
Echinococcus granulosus tar DNA binding protein 0.0064 0.0223 0.021
Loa Loa (eye worm) hypothetical protein 0.0075 0.0299 0.0296
Loa Loa (eye worm) hypothetical protein 0.0083 0.0354 0.0351
Entamoeba histolytica hypothetical protein 0.0144 0.0755 0.3035
Trichomonas vaginalis immunophilin, putative 0.04 0.2458 0.7664
Brugia malayi Bromodomain containing protein 0.0075 0.0298 0.0285
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0054 0.016 0.016
Brugia malayi hypothetical protein 0.0144 0.0755 0.0743
Loa Loa (eye worm) hypothetical protein 0.0032 0.0013 0.001
Schistosoma mansoni cathepsin B (C01 family) 0.0054 0.016 0.016
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0515 0.3218 0.3209
Loa Loa (eye worm) fli-1 protein 0.0229 0.1321 0.1318
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0182 0.1011 0.1011
Brugia malayi MAP kinase sur-1 0.0103 0.0488 0.0476
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0074 0.0291 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0054 0.016 0.0461
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0631
Brugia malayi beta-lactamase family protein 0.0107 0.051 0.0497
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0054 0.016 0.0601
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0515 0.3218 0.3218
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.012
Echinococcus multilocularis 0.0055 0.0168 0.0154
Trypanosoma cruzi calmodulin, putative 0.0032 0.0013 0.0013
Brugia malayi cathepsin F-like cysteine proteinase 0.0054 0.016 0.0147
Brugia malayi Myosin regulatory light chain 1 0.0044 0.0094 0.008
Giardia lamblia Encystation-specific protease 0.0054 0.016 0.0461
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0302 0.0299
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0054 0.016 0.016
Onchocerca volvulus 0.009 0.0399 0.2205
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.012
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0259 0.077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Trypanosoma cruzi kinesin, putative 0.0127 0.0648 0.0648
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0291 0.1134
Trichomonas vaginalis calmodulin, putative 0.0076 0.0305 0.0914
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0223 0.0223
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.009 0.0399 0.0396
Onchocerca volvulus 0.0301 0.1798 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0044 0.0094 0.0506
Onchocerca volvulus 0.0044 0.0094 0.0506
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.0157
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0032 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.016 0.016
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.1392 0.1381
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0502 0.0502
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0055 0.0165 0.0477
Loa Loa (eye worm) hypothetical protein 0.0107 0.051 0.0507
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0399 0.0399
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.016 0.016
Schistosoma mansoni hypothetical protein 0.0269 0.1589 0.1589
Mycobacterium tuberculosis Probable lipase LipD 0.0107 0.051 0.0388
Entamoeba histolytica cysteine protease, putative 0.009 0.0399 0.1576
Schistosoma mansoni immunophilin 0.04 0.2458 0.2458
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.0023 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.009 0.0399 0.0399
Schistosoma mansoni calpain C (C02 family) 0.0182 0.1011 0.1011
Trypanosoma brucei calmodulin, putative 0.0032 0.0013 0.0042
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0055 0.0165 0.0165
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.0157
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0055 0.0168 0.0483
Trypanosoma brucei caltractin, putative 0.0076 0.0305 0.0952
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0058 0.0308
Schistosoma mansoni myosin regulatory light chain 0.0044 0.0094 0.0094
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0069 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0055 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.1538 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0157
Trypanosoma cruzi calmodulin, putative 0.0032 0.0013 0.0013
Schistosoma mansoni transcription factor LCR-F1 0.0144 0.0755 0.0755
Echinococcus granulosus GPCR family 2 0.0125 0.0629 0.0616
Loa Loa (eye worm) hypothetical protein 0.0107 0.051 0.0507
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.04 0.2458 1
Schistosoma mansoni reticulocalbin 0.0032 0.0013 0.0013
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0074 0.0291 0.1134
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0057 0.0057
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0083 0.007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0125 0.0629 0.0616
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0513 0.3203 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Schistosoma mansoni centrin-related 0.0032 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.051 0.051
Plasmodium vivax hypothetical protein, conserved 0.0107 0.051 0.2032
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Plasmodium vivax vivapain-2 0.009 0.0399 0.1576
Schistosoma mansoni cathepsin F (C01 family) 0.009 0.0399 0.0399
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0107 0.051 0.0507
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0074 0.0291 0.014
Trypanosoma cruzi centrin, putative 0.0076 0.0305 0.0305
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0144 0.0755 0.0743
Echinococcus granulosus polycomb protein SCMH1 0.0093 0.0419 0.0407
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.051 0.1557
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.0488 0.0486
Loa Loa (eye worm) hypothetical protein 0.0107 0.051 0.0507
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0057 0.0044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0267 0.0254
Echinococcus granulosus cathepsin b 0.1538 1 1
Onchocerca volvulus 0.0055 0.0168 0.0917
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0057 0.0044
Loa Loa (eye worm) fibroinase 0.009 0.0399 0.0396
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0753 0.4796 0.4794
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0116 0.0575 0.0562
Trypanosoma cruzi Aph-1 protein, putative 0.0293 0.1748 0.1748
Loa Loa (eye worm) calpain D 0.0055 0.0165 0.0163
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.04 0.2458 0.7664
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0054 0.016 0.0461
Schistosoma mansoni hypothetical protein 0.0041 0.0073 0.0073
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0055 0.0165 0.0477
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0226 0.1298 0.1287
Brugia malayi Glycosyl hydrolases family 31 protein 0.017 0.0927 0.0915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Giardia lamblia Cathepsin B precursor 0.0054 0.016 0.0461
Leishmania major calcineurin B subunit, putative 0.0032 0.0013 0.0042
Trypanosoma brucei hypothetical protein, conserved 0.0055 0.0168 0.0523
Onchocerca volvulus 0.0044 0.0094 0.0506
Plasmodium falciparum cysteine proteinase falcipain 2b 0.009 0.0399 0.1576
Schistosoma mansoni sex comb on midleg homolog 0.0093 0.0419 0.0419
Trichomonas vaginalis centrin, putative 0.0044 0.0094 0.0252
Loa Loa (eye worm) hypothetical protein 0.0032 0.0013 0.001
Brugia malayi calpain 5 0.0127 0.0648 0.0635
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.016 0.016
Echinococcus granulosus tissue type plasminogen activator 0.0034 0.0028 0.0015
Mycobacterium ulcerans lipase LipD 0.0107 0.051 0.0388
Echinococcus granulosus cathepsin L 0.0069 0.0257 0.0244
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.051 0.1557
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.04 0.2458 0.7664
Brugia malayi Heterochromatin protein 1 0.0069 0.0259 0.0246
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0054 0.016 0.0601
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1538 1 1
Onchocerca volvulus Huntingtin homolog 0.012 0.06 0.3326
Echinococcus multilocularis Myosin regulatory light chain 0.0044 0.0094 0.008
Loa Loa (eye worm) cysteine protease 0.009 0.0399 0.0396
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.051 0.1557
Trichomonas vaginalis calpain, putative 0.0055 0.0165 0.0477
Schistosoma mansoni neuronal calcium sensor 0.0032 0.0013 0.0013
Onchocerca volvulus 0.009 0.0399 0.2205
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.0488 0.1489
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Trypanosoma brucei calpain-like protein, putative 0.0182 0.1011 0.3156
Toxoplasma gondii kringle domain-containing protein 0.0034 0.0028 0.0047
Onchocerca volvulus 0.0255 0.1495 0.8314
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0502 0.0502
Leishmania major hypothetical protein, conserved 0.0055 0.0165 0.0516
Onchocerca volvulus 0.009 0.0399 0.2205
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0345 0.2093 0.2082
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.04 0.2458 0.2448
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0054 0.016 0.0601
Trypanosoma brucei glucosidase, putative 0.0038 0.0052 0.0161
Loa Loa (eye worm) RNA binding protein 0.0064 0.0223 0.0221
Schistosoma mansoni Mername-AA248 (C02 family) 0.0182 0.1011 0.1011
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Trypanosoma cruzi cysteine proteinase, putative 0.0069 0.0257 0.0257
Toxoplasma gondii calcium binding protein precursor, putative 0.0044 0.0094 0.0252
Loa Loa (eye worm) calpain family protein 1 0.0483 0.3007 0.3005
Leishmania major calpain protease-like protein 0.0055 0.0165 0.0516
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.016 0.0147
Loa Loa (eye worm) hypothetical protein 0.0107 0.051 0.0507
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.016 0.016
Onchocerca volvulus 0.0153 0.0818 0.4542
Echinococcus multilocularis calcyphosin protein 0.0044 0.0094 0.008
Brugia malayi hypothetical protein 0.012 0.06 0.0587
Echinococcus multilocularis cathepsin l cysteine peptidase 0.009 0.0399 0.0386
Trichomonas vaginalis fk506-binding protein, putative 0.04 0.2458 0.7664
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0226 0.1298 0.1287
Giardia lamblia Cysteine protease 0.0054 0.016 0.0461
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Schistosoma mansoni hypothetical protein 0.0581 0.3654 0.3654
Schistosoma mansoni hypothetical protein 0.0032 0.0013 0.0013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.009 0.0399 0.0396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.016 0.0461
Toxoplasma gondii preprocathepsin c precursor, putative 0.0054 0.016 0.0461
Brugia malayi calpain family protein 1 0.0483 0.3007 0.2998
Entamoeba histolytica cysteine protease, putative 0.0054 0.016 0.0601
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0502 0.1997
Schistosoma mansoni hypothetical protein 0.0125 0.0629 0.0629
Onchocerca volvulus Cathepsin L homolog 0.0054 0.016 0.0877
Mycobacterium leprae conserved hypothetical protein 0.0107 0.051 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.016 0.0461
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1538 1 1
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.04 0.2458 0.2458
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0394 0.2416 0.2406
Schistosoma mansoni survival motor neuron protein 0.0049 0.0126 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Trichomonas vaginalis centrin, putative 0.0044 0.0094 0.0252
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0054 0.016 0.0601
Giardia lamblia Cathepsin L precursor 0.0054 0.016 0.0461
Loa Loa (eye worm) myosin regulatory light chain 1 0.0044 0.0094 0.0091
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0074 0.0291 0.0278
Echinococcus granulosus expressed conserved protein 0.0093 0.0417 0.0404
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0457 0.1814
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0057 0.0057
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0055 0.0165 0.0165
Onchocerca volvulus 0.0107 0.051 0.2825
Mycobacterium ulcerans beta-lactamase 0.0107 0.051 0.0388
Schistosoma mansoni bromodomain containing protein 0.0123 0.0621 0.0621
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.04 0.2458 0.7673
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0032 0.0013 0.0013
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Trichomonas vaginalis calmodulin, putative 0.0044 0.0094 0.0252
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0044 0.0094 0.0252
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0182 0.1011 0.1011
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0259 0.0256
Schistosoma mansoni ets-related 0.0229 0.1321 0.1321
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0182 0.1011 0.1011
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.012
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0054 0.016 0.0601
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0502 0.0489
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0182 0.1011 0.1011
Entamoeba histolytica cysteine proteinase, putative 0.0069 0.0257 0.0997
Loa Loa (eye worm) FKBP5 protein 0.04 0.2458 0.2456
Brugia malayi cathepsin Z-like cysteine proteinase 0.0054 0.016 0.0147
Echinococcus multilocularis zinc finger protein 0.0038 0.0055 0.0042
Loa Loa (eye worm) hypothetical protein 0.0044 0.0094 0.0091
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.016 0.016
Schistosoma mansoni alpha glucosidase 0.0038 0.0052 0.0052
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0126 0.0113
Leishmania major cysteine peptidase A (CPA) 0.009 0.0399 0.1245
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0054 0.016 0.016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Schistosoma mansoni calpain-7 (C02 family) 0.0185 0.1032 0.1032
Brugia malayi Neuronal calcium sensor family protein 1 0.0044 0.0094 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0032 0.0013 0.0013
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0034 0.0028 0.0061
Plasmodium falciparum centrin-4 0.0044 0.0094 0.0328
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Trichomonas vaginalis calpain, putative 0.0055 0.0165 0.0477
Trichomonas vaginalis fk506-binding protein, putative 0.0055 0.0168 0.0483
Toxoplasma gondii EF hand domain-containing protein 0.0044 0.0094 0.0252
Entamoeba histolytica hypothetical protein 0.0144 0.0755 0.3035
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.04 0.2458 0.2458
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0054 0.016 0.016
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0488 0.1489
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0157
Brugia malayi Trypsin family protein 0.028 0.1661 0.165
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0502 0.1531
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0226 0.1298 0.1298
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0144 0.0755 0.0743
Toxoplasma gondii calcium-dependent protein kinase 0.0033 0.002 0.0019
Loa Loa (eye worm) bromodomain containing protein 0.0034 0.0031 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.016 0.0461
Schistosoma mansoni ap endonuclease 0.0074 0.0291 0.0291
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0488 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0058 0.0141
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0523
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0052 0.012
Schistosoma mansoni ap endonuclease 0.0074 0.0291 0.0291
Loa Loa (eye worm) latrophilin receptor protein 2 0.0125 0.0629 0.0626
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0023 0.0009
Echinococcus granulosus cathepsin l cysteine peptidase 0.009 0.0399 0.0386
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0502 0.0499
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.0488 0.0476
Onchocerca volvulus 0.0032 0.0013 0.0058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0057 0.0057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1538 1 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0153 0.0818 0.0816
Schistosoma mansoni calmodulin 0.0032 0.0013 0.0013
Schistosoma mansoni calmodulin-related 0.0044 0.0094 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.016 0.0461
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0954 0.2949
Brugia malayi Cathepsin L-like precursor 0.009 0.0399 0.0386
Leishmania major hypothetical protein, conserved 0.0107 0.051 0.1592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.1011
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0502 0.1531
Schistosoma mansoni sex comb on midleg homolog 0.0093 0.0419 0.0419
Schistosoma mansoni hypothetical protein 0.004 0.0069 0.0069
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0107 0.051 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Mycobacterium leprae Probable lipase LipE 0.0107 0.051 1
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0033 0.002 0.002
Plasmodium falciparum serine repeat antigen 9 0.0054 0.016 0.0601
Loa Loa (eye worm) PHD-finger family protein 0.004 0.0069 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0488 0.1489
Onchocerca volvulus 0.0093 0.0419 0.232
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Loa Loa (eye worm) MBCTL1 0.0106 0.0505 0.0502
Entamoeba histolytica cysteine protease, putative 0.0054 0.016 0.0601
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0125 0.0629 0.0616
Leishmania major hypothetical protein, conserved 0.0034 0.0028 0.0088
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0069 0.0257 0.0257
Brugia malayi Ets-domain containing protein 0.0075 0.0302 0.0289
Leishmania major calmodulin-like protein 0.0032 0.0013 0.0042
Plasmodium vivax vivapain-1 0.0069 0.0257 0.0997
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0502 0.0499
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1468 0.4561
Brugia malayi Cathepsin L-like precursor 0.009 0.0399 0.0386
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0157
Toxoplasma gondii ABC1 family protein 0.0107 0.051 0.1557
Echinococcus granulosus programmed cell death protein 6 0.0044 0.0094 0.008
Trypanosoma brucei centrin-3 0.0076 0.0305 0.0952
Schistosoma mansoni calpain (C02 family) 0.0182 0.1011 0.1011
Trypanosoma brucei Calpain-like protein 1.2 0.0055 0.0165 0.0516
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0054 0.016 0.0461
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0069 0.0257 0.0257
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0226 0.1298 0.1287
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Echinococcus multilocularis cysteine protease 0.009 0.0399 0.0386
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0055 0.0168 0.0165
Mycobacterium tuberculosis Probable hydrolase 0.0107 0.051 0.0388
Trichomonas vaginalis calcium binding protein, putative 0.0044 0.0094 0.0252
Giardia lamblia Cathepsin L precursor 0.0054 0.016 0.0461
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0055 0.0168 0.5
Loa Loa (eye worm) hypothetical protein 0.0107 0.051 0.0507
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0257 0.0764
Mycobacterium ulcerans esterase/lipase LipP 0.0107 0.051 0.0388
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.016 0.0461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0054 0.016 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0168 0.0483
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0382 0.2333 0.2323
Schistosoma mansoni hypothetical protein 0.0055 0.0168 0.0168
Schistosoma mansoni calmodulin related calcium binding protein 0.0032 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0138 0.0717 0.0715
Leishmania major centrin, putative,caltractin, putative 0.0032 0.0013 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0055 0.0165 0.0165
Echinococcus granulosus zinc finger protein 0.0038 0.0055 0.0042
Schistosoma mansoni immunophilin 0.04 0.2458 0.2458
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.028 0.1661 0.1661
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0182 0.1011 0.1011
Plasmodium falciparum serine repeat antigen 1 0.0054 0.016 0.0601
Brugia malayi RNA binding protein 0.0064 0.0223 0.021
Entamoeba histolytica hypothetical protein 0.0054 0.016 0.0601
Brugia malayi calpain 7 0.0182 0.1011 0.0999
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.04 0.2458 0.2599
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0054 0.016 0.0601
Echinococcus granulosus gamma secretase subunit aph 1 0.0753 0.4796 0.4789
Brugia malayi hypothetical protein 0.024 0.1392 0.1381
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0054 0.016 0.0601
Loa Loa (eye worm) hypothetical protein 0.028 0.1661 0.1658
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0057 0.0044
Brugia malayi exodeoxyribonuclease III family protein 0.0074 0.0291 0.0278
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Plasmodium falciparum cysteine proteinase falcipain 2a 0.009 0.0399 0.1576
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.016 0.0461
Onchocerca volvulus Huntingtin homolog 0.012 0.06 0.3326
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0054 0.016 0.0461
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0055 0.0165 0.0165
Schistosoma mansoni myelin transcription factor 1 myt1 0.0106 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0106 0.0505 0.0502
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0057 0.0057
Entamoeba histolytica cysteine proteinase, putative 0.0069 0.0257 0.0997
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.051 0.051
Trypanosoma brucei Calpain-like protein 1.1 0.0055 0.0165 0.0516
Toxoplasma gondii cathepsin CPC2 0.0054 0.016 0.0461
Echinococcus multilocularis chromobox protein 1 0.0069 0.0259 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0257 0.0764
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0055 0.0165 0.0165
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0182 0.1011 0.3156
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0502 0.1566
Entamoeba histolytica cysteine protease, putative 0.0054 0.016 0.0601
Loa Loa (eye worm) hypothetical protein 0.0042 0.0083 0.008
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.04 0.2458 0.2448
Loa Loa (eye worm) hypothetical protein 0.012 0.06 0.0597
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0074 0.0291 0.0869
Onchocerca volvulus 0.0032 0.0013 0.0058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Brugia malayi phosphofructokinase 0.0105 0.0502 0.0489
Echinococcus multilocularis gamma secretase subunit aph 1 0.0753 0.4796 0.4789
Schistosoma mansoni myosin regulatory light chain 0.0044 0.0094 0.0094
Entamoeba histolytica cysteine proteinase, putative 0.009 0.0399 0.1576
Echinococcus multilocularis histone acetyltransferase MYST2 0.0106 0.0505 0.0492
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.016 0.0461
Loa Loa (eye worm) hypothetical protein 0.0301 0.1798 0.1796
Schistosoma mansoni gabp alpha 0.0075 0.0302 0.0302
Echinococcus granulosus cathepsin b 0.1538 1 1
Plasmodium falciparum serine repeat antigen 3 0.0054 0.016 0.0601
Loa Loa (eye worm) hypothetical protein 0.028 0.1661 0.1658
Echinococcus multilocularis neuropeptide s receptor 0.0484 0.3013 0.3004
Onchocerca volvulus 0.0075 0.0302 0.1667
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0083 0.007
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.04 0.2458 0.2456
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0055 0.0165 0.0477
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0033 0.002 0.002
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.0488 0.0488
Echinococcus granulosus geminin 0.1015 0.6535 0.653
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Schistosoma mansoni chromobox protein 0.0069 0.0259 0.0259
Echinococcus granulosus cysteine protease 0.0069 0.0257 0.0244
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.3156
Brugia malayi Latrophilin receptor protein 2 0.0125 0.0629 0.0616
Schistosoma mansoni neuronal calcium sensor 0.0032 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0094 0.0094
Trypanosoma brucei cysteine peptidase C (CPC) 0.0513 0.3203 1
Trypanosoma cruzi caltractin, putative 0.0032 0.0013 0.0013
Echinococcus multilocularis chromobox protein 1 0.0069 0.0259 0.0246
Schistosoma mansoni hypothetical protein 0.0032 0.0013 0.0013
Plasmodium vivax serine-repeat antigen (SERA) 0.0054 0.016 0.0601
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0055 0.0168 0.0523
Schistosoma mansoni hypothetical protein 0.0034 0.0028 0.0028
Plasmodium falciparum serine repeat antigen 5 0.0054 0.016 0.0601
Toxoplasma gondii centrin family protein 0.0044 0.0094 0.0252
Giardia lamblia Cathepsin L precursor 0.0054 0.016 0.0461
Entamoeba histolytica cysteine proteinase, putative 0.009 0.0399 0.1576
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.017 0.0927 0.0925
Loa Loa (eye worm) hypothetical protein 0.009 0.0399 0.0396
Loa Loa (eye worm) hypothetical protein 0.0079 0.0329 0.0327
Schistosoma mansoni hypothetical protein 0.0041 0.0073 0.0073
Toxoplasma gondii calmodulin, putative 0.0044 0.0094 0.0252
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0074 0.0291 0.0288
Onchocerca volvulus 0.0032 0.0013 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1468 0.4561
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0023 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.051 0.1557
Onchocerca volvulus 0.0098 0.0453 0.2507
Echinococcus granulosus cathepsin L 0.0054 0.016 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Giardia lamblia Cathepsin L precursor 0.0054 0.016 0.0461
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.016 0.016
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.012
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0257 0.0257
Echinococcus multilocularis fk506 binding protein 0.04 0.2458 0.2448
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Echinococcus multilocularis polycomb protein SCMH1 0.0093 0.0419 0.0407
Trypanosoma brucei Calpain-like protein 2 0.0055 0.0165 0.0516
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0074 0.0291 0.0291
Leishmania major calmodulin-like protein 0.0032 0.0013 0.0042
Plasmodium falciparum serine repeat antigen 8 0.0054 0.016 0.0601
Trypanosoma brucei calpain, putative 0.0055 0.0165 0.0516
Schistosoma mansoni ef hand domain family member A2 0.0032 0.0013 0.0013
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.04 0.2458 1
Trypanosoma cruzi cruzipain precursor, putative 0.009 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0345 0.2093 0.209
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0515 0.3218 0.3209
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0052 0.0049
Schistosoma mansoni cathepsin S (C01 family) 0.0054 0.016 0.016
Trypanosoma cruzi conserved protein 0.0055 0.0165 0.0165
Trypanosoma brucei hypothetical protein 0.0055 0.0165 0.0516
Leishmania major centrin, putative 0.0032 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0356 0.2162 0.2159
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.012
Trypanosoma brucei cysteine peptidase, putative 0.0055 0.0165 0.0516
Trypanosoma brucei antigen, putative 0.0182 0.1011 0.3156
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0057 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0058 0.0141
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0226 0.1298 0.1287
Leishmania major cathepsin L-like protease 0.009 0.0399 0.1245
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.009 0.0399 0.1208
Trypanosoma cruzi cysteine proteinase, putative 0.0069 0.0257 0.0257
Trypanosoma brucei mitochondrial calcium uptake 1 0.0032 0.0013 0.0042
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.04 0.2458 1
Brugia malayi fibroinase precursor 0.0054 0.016 0.0147
Brugia malayi Papain family cysteine protease containing protein 0.0069 0.0257 0.0244
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.0488 0.1524
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Trypanosoma brucei I/6 autoantigen 0.0032 0.0013 0.0042
Toxoplasma gondii cathepsin CPL 0.009 0.0399 0.1208
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Brugia malayi calpain 5 0.0055 0.0165 0.0152
Brugia malayi hypothetical protein 0.0153 0.0818 0.0806
Echinococcus multilocularis GPCR, family 2 0.0125 0.0629 0.0616
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0927 0.0915
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0054 0.016 0.0461
Giardia lamblia Cathepsin B precursor 0.0054 0.016 0.0461
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0055 0.0165 0.0516
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0052 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0226 0.1298 0.1298
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0057 0.0179
Loa Loa (eye worm) mbt repeat family protein 0.0093 0.0419 0.0417
Entamoeba histolytica cysteine protease, putative 0.0069 0.0257 0.0997
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0457 0.0444
Echinococcus granulosus survival motor neuron protein 1 0.024 0.1392 0.1381
Entamoeba histolytica grainin 2 0.0044 0.0094 0.0328
Echinococcus multilocularis calpain 5 0.0182 0.1011 0.0999
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1538 1 1
Onchocerca volvulus 0.009 0.0399 0.2205
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0055 0.0168 0.0483
Trypanosoma brucei hypothetical protein, conserved 0.0032 0.0013 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0165
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0074 0.0291 0.0907
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.051 0.051
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0055 0.0168 0.0523
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0895 0.2765
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.04 0.2458 0.2458
Trypanosoma cruzi I/6 autoantigen, putative 0.0032 0.0013 0.0013
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0057 0.0044
Echinococcus granulosus chromobox protein 1 0.0069 0.0259 0.0246
Echinococcus multilocularis beta LACTamase domain containing family member 0.0107 0.051 0.0497
Loa Loa (eye worm) hypothetical protein 0.0483 0.3007 0.3005
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.0488 0.1489
Brugia malayi Bromodomain containing protein 0.0146 0.0773 0.076
Schistosoma mansoni immunophilin 0.0345 0.2093 0.2093
Plasmodium falciparum serine repeat antigen 6 0.0054 0.016 0.0601
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0226 0.1298 0.1296
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0788 0.5031 0.5024
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0165 0.0477
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0052 0.012
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.016 0.0147
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.04 0.2458 0.2458
Entamoeba histolytica calpain family cysteine protease, putative 0.0055 0.0165 0.0622
Loa Loa (eye worm) calpain 0.0182 0.1011 0.1008
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0291 0.0869
Loa Loa (eye worm) hypothetical protein 0.0093 0.0419 0.0417
Brugia malayi cathepsin L-like precursor 0.0075 0.0302 0.0289
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0895 0.2765
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0057 0.0138
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0382 0.2333 0.2323
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0055 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0075 0.0302 0.0299
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.1395 0.1392
Giardia lamblia Cathepsin B precursor 0.0513 0.3203 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0054 0.016 0.0147
Brugia malayi Cathepsin L-like precursor 0.009 0.0399 0.0386
Echinococcus granulosus calpain 7 C02 family 0.0182 0.1011 0.0999
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0054 0.016 0.0461
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0023 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Brugia malayi Cathepsin L-like precursor 0.009 0.0399 0.0386
Echinococcus granulosus chromobox protein 1 0.0069 0.0259 0.0246
Giardia lamblia Cathepsin B precursor 0.0054 0.016 0.0461
Echinococcus multilocularis hypothetical protein 0.0182 0.1011 0.0999
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0483 0.3007 0.3007
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0106 0.0505 0.0492
Leishmania major centrin, putative 0.0032 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0054 0.016 0.0157
Loa Loa (eye worm) hypothetical protein 0.0034 0.0028 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.009 0.0399 0.0386
Plasmodium falciparum serine repeat antigen 4 0.0054 0.016 0.0601
Giardia lamblia Hypothetical protein 0.0054 0.016 0.0461
Brugia malayi Papain family cysteine protease containing protein 0.0069 0.0257 0.0244
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0057 0.0138
Loa Loa (eye worm) programmed cell death protein 6 0.0032 0.0013 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0028 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0257 0.0802
Trypanosoma cruzi calmodulin, putative 0.0032 0.0013 0.0013
Trypanosoma cruzi centrin, putative 0.0076 0.0305 0.0305
Trypanosoma brucei protein I/6 0.0032 0.0013 0.0042
Entamoeba histolytica cysteine protease, putative 0.0054 0.016 0.0601
Brugia malayi Calcitonin receptor-like protein seb-1 0.0394 0.2416 0.2406
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0044 0.0094 0.0094
Trichomonas vaginalis kakapo, putative 0.0044 0.0094 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0257 0.0802
Brugia malayi Probable myosin regulatory light chain 0.0044 0.0094 0.008
Toxoplasma gondii cathepsin B 0.0513 0.3203 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0457 0.0444
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0033 0.002 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0052 0.0052
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0182 0.1011 0.1011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.0302 0.0905
Trypanosoma brucei kinesin, putative 0.0127 0.0648 0.2021
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0055 0.0168 0.0165
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0291 0.0869
Brugia malayi MH2 domain containing protein 0.024 0.1395 0.1383
Echinococcus multilocularis cathepsin b 0.1538 1 1
Trichomonas vaginalis centrin, putative 0.0044 0.0094 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.009 0.0399 0.1208
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.04 0.2458 0.7673
Echinococcus granulosus calpain A 0.0515 0.3218 0.3209
Trichomonas vaginalis fk506-binding protein, putative 0.0055 0.0168 0.0483
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0033 0.0023 0.0009
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0052 0.0038
Giardia lamblia Cathepsin L-like protease 0.0054 0.016 0.0461
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0927 0.0915
Trypanosoma brucei calpain-like protein, putative 0.0182 0.1011 0.3156
Schistosoma mansoni myosin light chain 0.0044 0.0094 0.0094
Brugia malayi Cathepsin L-like precursor 0.0075 0.0302 0.0289
Echinococcus multilocularis calpain family protein 1, d 0.0356 0.2162 0.2151
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0055 0.0165 0.0477
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0502 0.1531
Leishmania major hypothetical protein, unknown function 0.0055 0.0165 0.0516
Entamoeba histolytica cysteine proteinase 2 0.0069 0.0257 0.0997
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0054 0.016 0.0157
Plasmodium vivax serine-repeat antigen (SERA) 0.0054 0.016 0.0601
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Echinococcus granulosus calpain 5 0.0182 0.1011 0.0999
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0223 0.0223
Giardia lamblia Hypothetical protein 0.0055 0.0168 0.0483
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0055 0.0168 0.0165
Leishmania major programmed cell death 6 protein-like protein 0.0032 0.0013 0.0042
Brugia malayi Kringle domain containing protein 0.0034 0.0028 0.0015
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0513 0.3203 0.3203
Onchocerca volvulus 0.0034 0.0028 0.0142
Leishmania major peptidylprolyl isomerase-like protein 0.04 0.2458 0.7673
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0523
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0226 0.1298 0.1287
Onchocerca volvulus 0.028 0.1661 0.9236
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0302 0.0289
Mycobacterium ulcerans short chain dehydrogenase 0.1384 0.8982 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0094 0.0091
Trypanosoma cruzi kinesin, putative 0.0127 0.0648 0.0648
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0052 0.0038
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0168
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0631
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.0023 0.0023
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.016 0.0147
Leishmania major calpain family cysteine protease-like protein 0.0055 0.0165 0.0516
Schistosoma mansoni calpain-7 (C02 family) 0.0185 0.1032 0.1032
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0168 0.0523
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0055 0.0168 0.0483
Plasmodium falciparum serine repeat antigen 7 0.0054 0.016 0.0601
Trypanosoma brucei calpain-like protein, putative 0.0182 0.1011 0.3156
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0054 0.016 0.0601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.009 0.0399 0.1208
Mycobacterium tuberculosis Probable oxidoreductase 0.1384 0.8982 1
Brugia malayi mbt repeat family protein 0.0093 0.0419 0.0407
Toxoplasma gondii exonuclease III APE 0.0074 0.0291 0.0869
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.04 0.2458 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0057 0.0044
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0457 0.0444
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0513 0.3203 0.3203
Onchocerca volvulus 0.0055 0.0168 0.0917
Plasmodium vivax calpain, putative 0.0182 0.1011 0.4081
Trypanosoma cruzi I/6 autoantigen, putative 0.0032 0.0013 0.0013
Echinococcus multilocularis cathepsin b 0.1538 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.009 0.0399 0.0399
Echinococcus granulosus fetal alzheimer antigen falz 0.0044 0.0094 0.0081
Echinococcus multilocularis calpain A 0.0515 0.3218 0.3209
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0074 0.0291 0.0907
Schistosoma mansoni reticulocalbin 0.0032 0.0013 0.0013
Echinococcus granulosus cathepsin L cysteine protease 0.0069 0.0257 0.0244
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0093 0.0419 0.0419
Schistosoma mansoni alpha-glucosidase 0.0146 0.0771 0.0771
Giardia lamblia Cathepsin B precursor 0.0054 0.016 0.0461
Loa Loa (eye worm) hypothetical protein 0.0039 0.0057 0.0055
Echinococcus multilocularis cathepsin L 0.0054 0.016 0.0147
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0032 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Loa Loa (eye worm) hypothetical protein 0.0075 0.0302 0.0299
Giardia lamblia Cathepsin L-like protease 0.0054 0.016 0.0461
Onchocerca volvulus Cathepsin F homolog 0.009 0.0399 0.2205
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Onchocerca volvulus 0.0049 0.0126 0.0688
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0895 0.4971
Entamoeba histolytica cysteine proteinase, putative 0.0069 0.0257 0.0997
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.051 0.1557
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0738 0.0726
Trypanosoma brucei centrin, putative 0.0032 0.0013 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0895 0.2765
Mycobacterium tuberculosis Probable esterase LipL 0.0107 0.051 0.0388
Entamoeba histolytica hypothetical protein 0.0144 0.0755 0.3035
Mycobacterium tuberculosis Conserved protein 0.0107 0.051 0.0388
Schistosoma mansoni rab 0.0032 0.0013 0.0013
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0054 0.016 0.0601
Giardia lamblia Cathepsin B precursor 0.0054 0.016 0.0461
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Giardia lamblia Programmed cell death protein-like protein 0.0044 0.0094 0.0252
Trichomonas vaginalis caltractin, putative 0.0044 0.0094 0.0252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.009 0.0399 0.1245
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0223 0.0221
Brugia malayi Fli-1 protein 0.0229 0.1321 0.1309
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0125 0.0629 0.0616
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0083 0.008
Echinococcus multilocularis calpain 0.0182 0.1011 0.0999
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0052 0.0038
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0055 0.0168 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0083 0.0219
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0055 0.0165 0.0516
Brugia malayi Protein kinase domain containing protein 0.0034 0.0028 0.0015
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0055 0.0168 0.0483
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0055 0.0165 0.0165
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0055 0.0168 0.0154
Plasmodium vivax unspecified product 0.0069 0.0257 0.0997
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0032 0.0013 0.0013
Trichomonas vaginalis hypothetical protein 0.0055 0.0165 0.0477
Echinococcus granulosus cathepsin l1 0.009 0.0399 0.0386
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0502 0.1997

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 65 nM Binding affinity towards rat 5-hydroxytryptamine 2A receptor expressed in NIH3T3 cells using [3H]-ketanserin as radioligand ChEMBL. 12930153
Ki (binding) = 65 nM Binding affinity towards rat 5-hydroxytryptamine 2A receptor expressed in NIH3T3 cells using [3H]-ketanserin as radioligand ChEMBL. 12930153
Ki (binding) = 90 nM Binding affinity towards rat 5-hydroxytryptamine 2C receptor expressed in A-9 cells using [3H]-mesulergine as radioligand ChEMBL. 12930153
Ki (binding) = 90 nM Binding affinity towards rat 5-hydroxytryptamine 2C receptor expressed in A-9 cells using [3H]-mesulergine as radioligand ChEMBL. 12930153
Ki (binding) = 875 nM Binding affinity towards mouse 5-hydroxytryptamine 5A receptor using LSD as radioligand ChEMBL. 12930153
Ki (binding) = 875 nM Binding affinity towards mouse 5-hydroxytryptamine 5A receptor using LSD as radioligand ChEMBL. 12930153

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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