Detailed information for compound 980250

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 241.245 | Formula: C13H11N3O2
  • H donors: 1 H acceptors: 2 LogP: 1.78 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc(C)c2c(n1)nc([nH]c2=O)c1ccco1
  • InChi: 1S/C13H11N3O2/c1-7-6-8(2)14-12-10(7)13(17)16-11(15-12)9-4-3-5-18-9/h3-6H,1-2H3,(H,14,15,16,17)
  • InChiKey: MACHSMDOCKSMSK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like precursor 0.0414 0.1878 0.1878
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0332 0.1458 0.4153
Loa Loa (eye worm) fibroinase 0.0591 0.2778 0.2778
Plasmodium falciparum serine repeat antigen 1 0.0156 0.0559 0.1464
Brugia malayi cathepsin F-like cysteine proteinase 0.0176 0.0664 0.0664
Schistosoma mansoni ef hand domain family member A2 0.0081 0.0178 0.0178
Entamoeba histolytica cysteine protease, putative 0.0156 0.0559 0.1464
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Loa Loa (eye worm) hypothetical protein 0.0176 0.0664 0.0664
Echinococcus multilocularis gamma secretase subunit aph 1 0.0246 0.1022 0.1022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2007 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Echinococcus granulosus calmodulin 0.0081 0.0178 0.0178
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0156 0.0559 0.1133
Trypanosoma cruzi major cysteine proteinase, putative 0.0156 0.0559 0.0537
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Schistosoma mansoni hypothetical protein 0.0081 0.0178 0.0178
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0145 0.0507 0.0994
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0176 0.0664 0.0664
Leishmania major i/6 autoantigen-like protein 0.0081 0.0178 0.0449
Echinococcus multilocularis expressed protein 0.0366 0.1631 0.1631
Echinococcus granulosus cathepsin L 0.0332 0.1458 0.1458
Loa Loa (eye worm) calpain 5 0.0358 0.1588 0.1588
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0081 0.0178 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0414 0.1878 0.515
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0503 0.233 0.2312
Entamoeba histolytica cysteine protease, putative 0.0156 0.0559 0.1464
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0081 0.0178 0.0178
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0183 0.0697 0.0697
Trypanosoma brucei Calpain-like protein CALP1.3 0.0145 0.0507 0.1399
Entamoeba histolytica cysteine proteinase, putative 0.0332 0.1458 0.4924
Brugia malayi Papain family cysteine protease containing protein 0.0156 0.0559 0.0559
Schistosoma mansoni centrin 0.0081 0.0178 0.0178
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0559 0.0559
Schistosoma mansoni cathepsin S (C01 family) 0.0156 0.0559 0.0559
Schistosoma mansoni gamma-secretase subunit aph-1 0.0246 0.1022 0.1022
Loa Loa (eye worm) calpain family protein 1 0.1347 0.6634 0.6634
Echinococcus multilocularis programmed cell death protein 0.0085 0.0197 0.0197
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0156 0.0559 0.1464
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Loa Loa (eye worm) hypothetical protein 0.0081 0.0178 0.0178
Brugia malayi Cathepsin L-like precursor 0.0591 0.2778 0.2778
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0081 0.0178 0.0156
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0156 0.0559 0.0559
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0728 0.3479 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Echinococcus granulosus calpain A 0.143 0.7054 0.7054
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0156 0.0559 0.1464
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0083 0.0186 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.6675
Entamoeba histolytica hypothetical protein 0.0156 0.0559 0.1464
Onchocerca volvulus 0.0083 0.0186 0.0018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0145 0.0507 0.0484
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0145 0.0507 0.0994
Giardia lamblia Cathepsin B precursor 0.0728 0.3479 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0156 0.0559 0.1464
Loa Loa (eye worm) hypothetical protein 0.0176 0.0664 0.0664
Brugia malayi Papain family cysteine protease containing protein 0.0156 0.0559 0.0559
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0145 0.0507 0.0484
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0127 0.0415 0.1132
Echinococcus multilocularis cathepsin b 0.2007 1 1
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Brugia malayi fibroinase precursor 0.0156 0.0559 0.0559
Echinococcus granulosus cysteine protease 0.0332 0.1458 0.1458
Echinococcus granulosus calbindin 32 0.0083 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.2007 1 1
Schistosoma mansoni neuronal calcium sensor 0.0081 0.0178 0.0178
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0156 0.0559 0.0559
Trypanosoma cruzi centrin, putative 0.0085 0.0197 0.0174
Schistosoma mansoni calpain C (C02 family) 0.0503 0.233 0.233
Echinococcus multilocularis cathepsin b 0.2007 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0591 0.2778 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0559 0.1153
Trypanosoma cruzi cysteine proteinase, putative 0.0332 0.1458 0.1439
Plasmodium falciparum cysteine proteinase falcipain 1 0.0332 0.1458 0.4924
Toxoplasma gondii calmodulin CAM1 0.0083 0.0186 0.0022
Schistosoma mansoni inhibitor of apoptosis protein 0.0183 0.0697 0.0697
Trypanosoma cruzi cruzipain precursor, putative 0.0176 0.0664 0.0643
Plasmodium falciparum calpain 0.0145 0.0507 0.1262
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.6675
Trypanosoma brucei cysteine peptidase C (CPC) 0.0728 0.3479 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0332 0.1458 0.1439
Echinococcus multilocularis neurocalcin 0.0081 0.0178 0.0178
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0503 0.233 0.2312
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Trichomonas vaginalis calpain, putative 0.0145 0.0507 0.0994
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0051 0.0023 0.5
Schistosoma mansoni calpain-7 (C02 family) 0.0503 0.233 0.233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Schistosoma mansoni Mername-AA248 (C02 family) 0.0503 0.233 0.233
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0728 0.3479 0.3464
Brugia malayi calpain 5 0.0145 0.0507 0.0507
Entamoeba histolytica cysteine proteinase 1, putative 0.0332 0.1458 0.4924
Echinococcus multilocularis calpain A 0.143 0.7054 0.7054
Trichomonas vaginalis calcium binding protein, putative 0.0085 0.0197 0.0055
Leishmania major cathepsin L-like protease 0.0591 0.2778 0.7971
Trypanosoma brucei Calpain-like protein 1.1 0.0145 0.0507 0.1399
Echinococcus multilocularis neuronal calcium sensor 0.0081 0.0178 0.0178
Trypanosoma cruzi prolyl endopeptidase 0.0127 0.0415 0.0392
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0145 0.0507 0.0994
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Plasmodium falciparum serine repeat antigen 6 0.0156 0.0559 0.1464
Echinococcus multilocularis hypothetical protein 0.0503 0.233 0.233
Onchocerca volvulus 0.0414 0.1878 0.4369
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0559 0.1153
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0156 0.0559 0.1133
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0591 0.2778 0.2778
Trichomonas vaginalis calpain, putative 0.0145 0.0507 0.0994
Plasmodium vivax vivapain-2 0.0591 0.2778 1
Onchocerca volvulus Cell death protein 3 homolog 0.0097 0.026 0.021
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0156 0.0559 0.1153
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0591 0.2778 0.2778
Schistosoma mansoni calmodulin related calcium binding protein 0.0081 0.0178 0.0178
Giardia lamblia Cathepsin L precursor 0.0156 0.0559 0.1133
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0081 0.0178 0.0156
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Echinococcus multilocularis programmed cell death protein 0.0085 0.0197 0.0197
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0559 0.0559
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0728 0.3479 0.3479
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0559 0.0559
Trypanosoma cruzi caltractin, putative 0.0081 0.0178 0.0156
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2007 1 1
Leishmania major cysteine peptidase A (CPA) 0.0591 0.2778 0.7971
Echinococcus multilocularis calbindin 32 0.0083 0.0186 0.0186
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Trypanosoma cruzi Aph-1 protein, putative 0.0096 0.0255 0.0232
Trypanosoma brucei antigen, putative 0.0503 0.233 0.6675
Loa Loa (eye worm) hypothetical protein 0.0081 0.0178 0.0178
Giardia lamblia Cathepsin B precursor 0.0728 0.3479 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Trichomonas vaginalis calmodulin, putative 0.0083 0.0186 0.0022
Trypanosoma brucei prolyl endopeptidase 0.0127 0.0415 0.1132
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0332 0.1458 0.1458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0591 0.2778 1
Toxoplasma gondii cathepsin B 0.0728 0.3479 1
Trichomonas vaginalis hypothetical protein 0.0145 0.0507 0.0994
Brugia malayi EF hand family protein 0.0083 0.0186 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0559 0.1153
Giardia lamblia Cathepsin L-like protease 0.0156 0.0559 0.1133
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0503 0.233 0.2312
Loa Loa (eye worm) hypothetical protein 0.0844 0.4069 0.4069
Schistosoma mansoni mitochondrial solute carrier 0.0081 0.0178 0.0178
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0183 0.0697 0.0697
Brugia malayi prolyl oligopeptidase family protein 0.0127 0.0415 0.0415
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0081 0.0178 0.0156
Trypanosoma cruzi centrin-3 0.0085 0.0197 0.0174
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0127 0.0415 0.0415
Brugia malayi Papain family cysteine protease containing protein 0.0591 0.2778 0.2778
Echinococcus granulosus calpain A 0.0503 0.233 0.233
Trypanosoma brucei centrin-3 0.0085 0.0197 0.0502
Echinococcus granulosus microtubule associated protein 2 0.0677 0.3215 0.3215
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1428 0.7047 0.7047
Leishmania major calpain family cysteine protease-like protein 0.0145 0.0507 0.1399
Schistosoma mansoni neuronal calcium sensor 0.0081 0.0178 0.0178
Echinococcus multilocularis cysteine protease 0.0591 0.2778 0.2778
Echinococcus granulosus apoptotic protease activating factor 1 0.0097 0.026 0.026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Trichomonas vaginalis conserved hypothetical protein 0.0145 0.0507 0.0994
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Toxoplasma gondii preprocathepsin c precursor, putative 0.0156 0.0559 0.1153
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0414 0.1878 0.515
Leishmania major hypothetical protein, unknown function 0.0145 0.0507 0.1399
Schistosoma mansoni neuronal calcium sensor 0.0081 0.0178 0.0178
Brugia malayi calpain family protein 1 0.1347 0.6634 0.6634
Loa Loa (eye worm) hypothetical protein 0.1347 0.6634 0.6634
Brugia malayi hypothetical protein 0.0097 0.026 0.026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.2312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Toxoplasma gondii cathepsin CPC2 0.0156 0.0559 0.1153
Brugia malayi cathepsin Z-like cysteine proteinase 0.0156 0.0559 0.0559
Echinococcus multilocularis EF hand domain containing family member A2 0.0083 0.0186 0.0186
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0156 0.0559 0.1464
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0461 0.2113 0.2095
Leishmania major cathepsin L-like protease 0.0637 0.3013 0.8651
Loa Loa (eye worm) hypothetical protein 0.0156 0.0559 0.0559
Entamoeba histolytica protein kinase, putative 0.0358 0.1588 0.5423
Echinococcus multilocularis inhibitor of apoptosis protein 0.0183 0.0697 0.0697
Echinococcus multilocularis calpain 5 0.0503 0.233 0.233
Schistosoma mansoni hypothetical protein 0.0097 0.026 0.026
Brugia malayi cathepsin Z-like cysteine proteinase 0.0156 0.0559 0.0559
Plasmodium vivax vivapain-2 0.0591 0.2778 1
Echinococcus multilocularis EF hand domain containing family member A2 0.0081 0.0178 0.0178
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0114 0.0346 0.3497
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Schistosoma mansoni cathepsin F (C01 family) 0.0591 0.2778 0.2778
Trypanosoma cruzi kinesin, putative 0.0358 0.1588 0.1568
Trypanosoma brucei calmodulin, putative 0.0081 0.0178 0.0449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0559 0.1153
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0156 0.0559 0.1153
Giardia lamblia Cathepsin B precursor 0.0156 0.0559 0.1133
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0145 0.0507 0.0484
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0156 0.0559 0.1153
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0156 0.0559 0.0559
Brugia malayi Cathepsin L-like precursor 0.0591 0.2778 0.2778
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Trypanosoma brucei Aph-1 protein, putative 0.0096 0.0255 0.067
Echinococcus multilocularis prolyl endopeptidase 0.0127 0.0415 0.0415
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0591 0.2778 1
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0156 0.0559 0.0559
Plasmodium falciparum serine repeat antigen 2 0.0156 0.0559 0.1464
Brugia malayi cathepsin L precursor 0.0156 0.0559 0.0559
Schistosoma mansoni neuronal calcium sensor 0.0081 0.0178 0.0178
Echinococcus multilocularis cathepsin L cysteine protease 0.0591 0.2778 0.2778
Brugia malayi Papain family cysteine protease containing protein 0.0156 0.0559 0.0559
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.0947 1
Schistosoma mansoni hypothetical protein 0.0183 0.0697 0.0697
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2007 1 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Schistosoma mansoni cathepsin F (C01 family) 0.0414 0.1878 0.1878
Trichomonas vaginalis calmodulin, putative 0.0085 0.0197 0.0055
Loa Loa (eye worm) hypothetical protein 0.0145 0.0507 0.0507
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0183 0.0697 0.0697
Entamoeba histolytica cysteine protease, putative 0.0591 0.2778 1
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0156 0.0559 0.1464
Leishmania major centrin, putative 0.0081 0.0178 0.0449
Schistosoma mansoni cathepsin F (C01 family) 0.0591 0.2778 0.2778
Echinococcus multilocularis calumenin 0.0083 0.0186 0.0186
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Trypanosoma cruzi calmodulin, putative 0.0081 0.0178 0.0156
Brugia malayi calpain D 0.0145 0.0507 0.0507
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Onchocerca volvulus 0.0591 0.2778 0.6681
Entamoeba histolytica calpain large subunit domain III containing protein 0.0358 0.1588 0.5423
Giardia lamblia Encystation-specific protease 0.0156 0.0559 0.1133
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.2312
Trypanosoma cruzi conserved protein 0.0145 0.0507 0.0484
Schistosoma mansoni caspase-7 (C14 family) 0.0097 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0414 0.1878 0.1878
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0332 0.1458 0.4153
Loa Loa (eye worm) cysteine protease 0.0591 0.2778 0.2778
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0145 0.0507 0.1399
Loa Loa (eye worm) hypothetical protein 0.0176 0.0664 0.0664
Leishmania major phospholipase c-like protein 0.0081 0.0178 0.0449
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Trypanosoma cruzi major cysteine proteinase, putative 0.0202 0.0794 0.0773
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0156 0.0559 0.1464
Leishmania major calmodulin, putative 0.0081 0.0178 0.0449
Onchocerca volvulus 0.0591 0.2778 0.6681
Echinococcus granulosus expressed protein 0.0366 0.1631 0.1631
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Plasmodium falciparum serine repeat antigen 7 0.0156 0.0559 0.1464
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0503 0.233 0.2312
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0559 0.0559
Brugia malayi Cathepsin L-like precursor 0.0591 0.2778 0.2778
Trypanosoma brucei calpain-like protein, putative 0.0503 0.233 0.6675
Onchocerca volvulus Cathepsin L homolog 0.0591 0.2778 0.6681
Loa Loa (eye worm) hypothetical protein 0.0156 0.0559 0.0559
Leishmania major centrin, putative 0.0081 0.0178 0.0449
Trypanosoma brucei protein I/6 0.0081 0.0178 0.0449
Echinococcus granulosus cathepsin L cysteine proteinase 0.0591 0.2778 0.2778
Schistosoma mansoni centrin-related 0.0081 0.0178 0.0178
Echinococcus granulosus calumenin 0.0083 0.0186 0.0186
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0145 0.0507 0.0484
Toxoplasma gondii cathepsin CPC1 0.0156 0.0559 0.1153
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Giardia lamblia Cathepsin L precursor 0.0156 0.0559 0.1133
Echinococcus multilocularis cathepsin L cysteine protease 0.0591 0.2778 0.2778
Leishmania major cathepsin L-like protease 0.0637 0.3013 0.8651
Loa Loa (eye worm) hypothetical protein 0.0591 0.2778 0.2778
Trichomonas vaginalis calcineurin B subunit, putative 0.0083 0.0186 0.0022
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0183 0.0697 0.0697
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0081 0.0178 0.0178
Giardia lamblia Cathepsin B precursor 0.0728 0.3479 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Echinococcus multilocularis calpain 0.0503 0.233 0.233
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0591 0.2778 0.7875
Schistosoma mansoni calpain-2 (C02 family) 0.0145 0.0507 0.0507
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0591 0.2778 0.2778
Trichomonas vaginalis conserved hypothetical protein 0.0156 0.0559 0.1153
Echinococcus granulosus cathepsin L 0.0156 0.0559 0.0559
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0183 0.0697 0.0697
Entamoeba histolytica hypothetical protein, conserved 0.0083 0.0186 0.0028
Toxoplasma gondii prolyl endopeptidase 0.0127 0.0415 0.0715
Trypanosoma brucei cysteine peptidase, putative 0.0145 0.0507 0.1399
Loa Loa (eye worm) hypothetical protein 0.0414 0.1878 0.1878
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0145 0.0507 0.0484
Brugia malayi Calmodulin-like protein 0.0081 0.0178 0.0178
Brugia malayi Cathepsin L-like precursor 0.0176 0.0664 0.0664
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0176 0.0664 0.0664
Brugia malayi cathepsin L-like precursor 0.0414 0.1878 0.1878
Toxoplasma gondii cathepsin CPL 0.0591 0.2778 0.7875
Leishmania major cathepsin L-like protease 0.0591 0.2778 0.7971
Trypanosoma brucei centrin, putative 0.0081 0.0178 0.0449
Entamoeba histolytica cysteine proteinase, putative 0.0332 0.1458 0.4924
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0081 0.0178 0.0449
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Plasmodium vivax serine-repeat antigen (SERA) 0.0156 0.0559 0.1464
Schistosoma mansoni calmodulin 0.0081 0.0178 0.0178
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0156 0.0559 0.1133
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Plasmodium vivax calpain, putative 0.0503 0.233 0.8277
Onchocerca volvulus Cathepsin L homolog 0.0156 0.0559 0.0978
Echinococcus granulosus centrin 2 0.0081 0.0178 0.0178
Trypanosoma brucei Component of motile flagella 41 0.0081 0.0178 0.0449
Onchocerca volvulus Cathepsin L homolog 0.0591 0.2778 0.6681
Brugia malayi cathepsin L-like cysteine proteinase 0.0156 0.0559 0.0559
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0145 0.0507 0.0484
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1428 0.7047 0.7047
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0728 0.3479 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0559 0.1153
Trypanosoma brucei I/6 autoantigen 0.0081 0.0178 0.0449
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0332 0.1458 0.1458
Entamoeba histolytica cysteine proteinase 2 0.0332 0.1458 0.4924
Loa Loa (eye worm) hypothetical protein 0.0127 0.0415 0.0415
Brugia malayi programmed cell death protein 6 0.0081 0.0178 0.0178
Echinococcus granulosus calcium uptake protein 1 0.0083 0.0186 0.0186
Echinococcus multilocularis cathepsin L 0.0332 0.1458 0.1458
Leishmania major calmodulin-like protein 0.0081 0.0178 0.0449
Onchocerca volvulus 0.0844 0.4069 1
Trypanosoma cruzi cysteine peptidase, putative 0.0591 0.2778 0.2761
Trypanosoma brucei calpain-like protein, putative 0.0503 0.233 0.6675
Giardia lamblia Cysteine protease 0.0156 0.0559 0.1133
Loa Loa (eye worm) hypothetical protein 0.1202 0.5892 0.5892
Giardia lamblia Cathepsin L precursor 0.0156 0.0559 0.1133
Schistosoma mansoni reticulocalbin 0.0081 0.0178 0.0178
Toxoplasma gondii calcium-dependent protein kinase 0.0083 0.0186 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0332 0.1458 0.1439
Onchocerca volvulus 0.0097 0.026 0.021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Plasmodium vivax unspecified product 0.0176 0.0664 0.1869
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0156 0.0559 0.1464
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.3215 0.3215
Loa Loa (eye worm) calmodulin-like protein 0.0081 0.0178 0.0178
Giardia lamblia Cathepsin L precursor 0.0156 0.0559 0.1133
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0051 0.0023 0.5
Giardia lamblia Cathepsin L precursor 0.0156 0.0559 0.1133
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0156 0.0559 0.0559
Echinococcus granulosus programmed cell death protein 0.0085 0.0197 0.0197
Trypanosoma cruzi cruzipain precursor, putative 0.0637 0.3013 0.2997
Leishmania major programmed cell death 6 protein-like protein 0.0081 0.0178 0.0449
Entamoeba histolytica cysteine protease, putative 0.0156 0.0559 0.1464
Leishmania major cathepsin L-like protease 0.0591 0.2778 0.7971
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0127 0.0415 0.0415
Echinococcus granulosus cathepsin b 0.2007 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0156 0.0559 0.1153
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0246 0.1022 0.1022
Giardia lamblia Cathepsin B precursor 0.0156 0.0559 0.1133
Loa Loa (eye worm) hypothetical protein 0.0156 0.0559 0.0559
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0559 0.1153
Brugia malayi calcium-binding protein 0.0081 0.0178 0.0178
Schistosoma mansoni cathepsin s 0.0176 0.0664 0.0664
Giardia lamblia Cysteine protease 0.0156 0.0559 0.1133
Echinococcus granulosus neurocalcin 0.0081 0.0178 0.0178
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Trypanosoma cruzi I/6 autoantigen, putative 0.0081 0.0178 0.0156
Leishmania major calmodulin-like protein 0.0081 0.0178 0.0449
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1428 0.7047 0.7047
Entamoeba histolytica cysteine proteinase, putative 0.0332 0.1458 0.4924
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.6675
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0081 0.0178 0.0156
Echinococcus multilocularis calpain 7 (C02 family) 0.0503 0.233 0.233
Brugia malayi Cathepsin L-like precursor 0.0591 0.2778 0.2778
Trypanosoma brucei kinesin, putative 0.0358 0.1588 0.4528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Trypanosoma cruzi centrin, putative 0.0085 0.0197 0.0174
Trypanosoma brucei hypothetical protein, conserved 0.0081 0.0178 0.0449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Brugia malayi calpain family protein 1 0.1347 0.6634 0.6634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Echinococcus granulosus calpain 0.0503 0.233 0.233
Brugia malayi Cell death protein 3 precursor 0.0097 0.026 0.026
Leishmania major hypothetical protein, conserved 0.0081 0.0178 0.0449
Echinococcus granulosus prolyl endopeptidase 0.0127 0.0415 0.0415
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0156 0.0559 0.0559
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0156 0.0559 0.1464
Echinococcus granulosus EF HAND 1 calcium binding site 0.0081 0.0178 0.0178
Echinococcus multilocularis calcium uptake protein 1 0.0083 0.0186 0.0186
Leishmania major cathepsin L-like protease 0.0591 0.2778 0.7971
Leishmania major cathepsin L-like protease 0.0591 0.2778 0.7971
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0156 0.0559 0.1153
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0559 0.1153
Leishmania major cathepsin L-like protease 0.0637 0.3013 0.8651
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0332 0.1458 0.3878
Entamoeba histolytica calpain family cysteine protease, putative 0.0145 0.0507 0.1262
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0081 0.0178 0.0178
Onchocerca volvulus 0.0591 0.2778 0.6681
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0081 0.0178 0.0449
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0156 0.0559 0.1153
Leishmania major protein kinase, putative 0.0081 0.0178 0.0449
Loa Loa (eye worm) hypothetical protein 0.0156 0.0559 0.0559
Leishmania major calpain protease-like protein 0.0145 0.0507 0.1399
Trypanosoma cruzi cysteine peptidase, putative 0.0637 0.3013 0.2997
Echinococcus granulosus EF hand domain containing family member A2 0.0083 0.0186 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Giardia lamblia Cathepsin L-like protease 0.0156 0.0559 0.1133
Echinococcus granulosus cathepsin b 0.2007 1 1
Trypanosoma brucei Calpain-like protein 2 0.0145 0.0507 0.1399
Entamoeba histolytica cysteine proteinase, putative 0.0332 0.1458 0.4924
Loa Loa (eye worm) ctsf protein 0.0591 0.2778 0.2778
Giardia lamblia Cathepsin B precursor 0.0156 0.0559 0.1133
Plasmodium falciparum serine repeat antigen 3 0.0156 0.0559 0.1464
Schistosoma mansoni calmodulin 0.0081 0.0178 0.0178
Onchocerca volvulus 0.0591 0.2778 0.6681
Brugia malayi Cathepsin L-like precursor 0.0414 0.1878 0.1878
Trypanosoma cruzi cysteine protease, putative 0.0332 0.1458 0.1439
Echinococcus multilocularis apoptotic protease activating factor 1 0.0097 0.026 0.026
Brugia malayi EF hand family protein 0.0081 0.0178 0.0178
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0591 0.2778 0.2778
Trypanosoma brucei centrin, putative 0.0081 0.0178 0.0449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0559 0.1153
Trypanosoma brucei calpain, putative 0.0145 0.0507 0.1399
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0145 0.0507 0.0994
Loa Loa (eye worm) hypothetical protein 0.0097 0.026 0.026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.6675
Leishmania major hypothetical protein, conserved 0.0083 0.0186 0.047
Leishmania major centrin, putative,caltractin, putative 0.0081 0.0178 0.0449
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0503 0.233 0.6675
Onchocerca volvulus 0.0183 0.0697 0.1332
Onchocerca volvulus Prolyl endopeptidase homolog 0.0127 0.0415 0.0607
Trypanosoma cruzi cysteine peptidase, putative 0.0176 0.0664 0.0643
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0186 0.0028
Loa Loa (eye worm) hypothetical protein 0.0183 0.0697 0.0697
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0145 0.0507 0.1399
Onchocerca volvulus Deterin homolog 0.0183 0.0697 0.1332
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Loa Loa (eye worm) hypothetical protein 0.0414 0.1878 0.1878
Loa Loa (eye worm) hypothetical protein 0.0097 0.026 0.026
Echinococcus granulosus neuronal calcium sensor 0.0081 0.0178 0.0178
Echinococcus multilocularis cathepsin L 0.0156 0.0559 0.0559
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0503 0.233 0.2312
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0145 0.0507 0.0994
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Plasmodium vivax unspecified product 0.0156 0.0559 0.1464
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0559 0.1153
Leishmania major calmodulin, putative 0.0081 0.0178 0.0449
Brugia malayi cathepsin F-like cysteine proteinase 0.0156 0.0559 0.0559
Onchocerca volvulus 0.0156 0.0559 0.0978
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0156 0.0559 0.1464
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0156 0.0559 0.1464
Plasmodium vivax vivapain-3 0.0332 0.1458 0.4924
Echinococcus multilocularis calmodulin 0.0081 0.0178 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.2312
Loa Loa (eye worm) hypothetical protein 0.0183 0.0697 0.0697
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0332 0.1458 0.3878
Schistosoma mansoni reticulocalbin 0.0083 0.0186 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0145 0.0507 0.0994
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0156 0.0559 0.1464
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Onchocerca volvulus 0.0591 0.2778 0.6681
Trichomonas vaginalis conserved hypothetical protein 0.0156 0.0559 0.1153
Entamoeba histolytica cysteine protease, putative 0.0156 0.0559 0.1464
Plasmodium falciparum serine repeat antigen 9 0.0156 0.0559 0.1464
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Echinococcus granulosus cathepsin l cysteine peptidase 0.0591 0.2778 0.2778
Loa Loa (eye worm) cathepsin B 0.0728 0.3479 0.3479
Entamoeba histolytica grainin 2 0.0085 0.0197 0.007
Trypanosoma cruzi calmodulin, putative 0.0081 0.0178 0.0156
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2007 1 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0156 0.0559 0.1464
Brugia malayi calpain 7 0.0503 0.233 0.233
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0559 0.0559
Entamoeba histolytica grainin, putative 0.0083 0.0186 0.0028
Trichomonas vaginalis calpain, putative 0.0145 0.0507 0.0994
Brugia malayi calpain 5 0.0358 0.1588 0.1588
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0156 0.0559 0.1464
Entamoeba histolytica cysteine proteinase, putative 0.0591 0.2778 1
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Loa Loa (eye worm) hypothetical protein 0.0989 0.481 0.481
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0156 0.0559 0.0559
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0145 0.0507 0.0484
Brugia malayi Cathepsin L-like precursor 0.0591 0.2778 0.2778
Trypanosoma brucei calmodulin, putative 0.0083 0.0186 0.047
Trypanosoma cruzi kinesin, putative 0.0358 0.1588 0.1568
Plasmodium vivax vivapain-1 0.0332 0.1458 0.4924
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1428 0.7047 0.7047
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Schistosoma mansoni calpain (C02 family) 0.0503 0.233 0.233
Giardia lamblia Hypothetical protein 0.0156 0.0559 0.1133
Brugia malayi Papain family cysteine protease containing protein 0.0332 0.1458 0.1458
Plasmodium falciparum serine repeat antigen 8 0.0156 0.0559 0.1464
Echinococcus granulosus cathepsin l1 0.0414 0.1878 0.1878
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0145 0.0507 0.0994
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.0484
Plasmodium falciparum serine repeat antigen 5 0.0156 0.0559 0.1464
Schistosoma mansoni rab 0.0081 0.0178 0.0178
Trypanosoma brucei calpain, putative 0.0145 0.0507 0.1399
Loa Loa (eye worm) calpain D 0.0145 0.0507 0.0507
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0503 0.233 0.2312
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.3215 0.3215
Trypanosoma cruzi cysteine peptidase, putative 0.0637 0.3013 0.2997
Schistosoma mansoni hypothetical protein 0.0081 0.0178 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Plasmodium falciparum cysteine proteinase falcipain 3 0.0591 0.2778 1
Echinococcus granulosus cathepsin L cysteine protease 0.0332 0.1458 0.1458
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0503 0.233 0.2312
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0156 0.0559 0.1464
Entamoeba histolytica cysteine protease, putative 0.0332 0.1458 0.4924
Onchocerca volvulus 0.0591 0.2778 0.6681
Onchocerca volvulus 0.0591 0.2778 0.6681
Trypanosoma cruzi calmodulin, putative 0.0081 0.0178 0.0156
Echinococcus multilocularis caspase 2 0.0097 0.026 0.026
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0145 0.0507 0.0484
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0145 0.0507 0.0484
Trypanosoma brucei calpain-like protein, putative 0.0503 0.233 0.6675
Trypanosoma cruzi I/6 autoantigen, putative 0.0081 0.0178 0.0156
Entamoeba histolytica cysteine protease, putative 0.0156 0.0559 0.1464
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0081 0.0178 0.0156
Loa Loa (eye worm) calpain 0.0503 0.233 0.233
Loa Loa (eye worm) hypothetical protein 0.0156 0.0559 0.0559
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0145 0.0507 0.1399
Trypanosoma cruzi Aph-1 protein, putative 0.0096 0.0255 0.0232
Toxoplasma gondii hypothetical protein 0.0145 0.0507 0.0994
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0156 0.0559 0.1153
Brugia malayi Cathepsin L-like precursor 0.0591 0.2778 0.2778
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0145 0.0507 0.1399
Loa Loa (eye worm) EF hand family protein 0.0081 0.0178 0.0178
Giardia lamblia Cathepsin L precursor 0.0156 0.0559 0.1133
Brugia malayi gamma-secretase subunit aph-1 0.0246 0.1022 0.1022
Giardia lamblia Cathepsin B precursor 0.0156 0.0559 0.1133
Entamoeba histolytica cysteine protease, putative 0.0156 0.0559 0.1464
Echinococcus granulosus gamma secretase subunit aph 1 0.0246 0.1022 0.1022
Echinococcus granulosus caspase 2 0.0097 0.026 0.026
Schistosoma mansoni cathepsin B (C01 family) 0.0156 0.0559 0.0559
Schistosoma mansoni cathepsin C 0.0156 0.0559 0.0559
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0156 0.0559 0.0559
Echinococcus granulosus calpain 7 C02 family 0.0503 0.233 0.233
Loa Loa (eye worm) programmed cell death protein 6 0.0083 0.0186 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0332 0.1458 0.1458
Giardia lamblia Cysteine protease 0.0156 0.0559 0.1133
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0156 0.0559 0.1464
Loa Loa (eye worm) hypothetical protein 0.0156 0.0559 0.0559
Loa Loa (eye worm) calpain family protein 1 0.0989 0.481 0.481
Schistosoma mansoni hypothetical protein 0.0145 0.0507 0.0507
Entamoeba histolytica cysteine proteinase, putative 0.0414 0.1878 0.6539
Leishmania major calcineurin B subunit, putative 0.0081 0.0178 0.0449
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0156 0.0559 0.1464
Trypanosoma cruzi cysteine peptidase, putative 0.0637 0.3013 0.2997
Echinococcus multilocularis calpain family protein 1, d 0.0989 0.481 0.481
Giardia lamblia Cathepsin B precursor 0.0156 0.0559 0.1133
Trypanosoma cruzi cysteine proteinase, putative 0.0332 0.1458 0.1439
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0591 0.2778 0.7875
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0145 0.0507 0.0484
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2007 1 1
Giardia lamblia Hypothetical protein 0.0156 0.0559 0.1133
Echinococcus granulosus inhibitor of apoptosis protein 0.0183 0.0697 0.0697
Plasmodium vivax unspecified product 0.0332 0.1458 0.4924
Echinococcus multilocularis calmodulin 0.0081 0.0178 0.0178
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0083 0.0186 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0559 0.1153
Echinococcus granulosus EF hand domain containing family member A2 0.0081 0.0178 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0637 0.3013 0.8651
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1347 0.6634 0.6634
Leishmania major kinesin, putative 0.0358 0.1588 0.4528
Onchocerca volvulus Cathepsin F homolog 0.0591 0.2778 0.6681
Trypanosoma brucei caltractin, putative 0.0085 0.0197 0.0502
Trypanosoma brucei calpain-like protein, putative 0.0503 0.233 0.6675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0591 0.2778 0.7875
Giardia lamblia Cysteine protease 0.0156 0.0559 0.1133
Trypanosoma brucei Calpain-like protein 1.2 0.0145 0.0507 0.1399
Brugia malayi Papain family cysteine protease containing protein 0.0332 0.1458 0.1458
Echinococcus multilocularis cysteine protease 0.0591 0.2778 0.2778
Brugia malayi Cathepsin L-like cysteine proteinase 0.0414 0.1878 0.1878
Echinococcus granulosus cathepsin l1 0.0591 0.2778 0.2778
Trypanosoma brucei hypothetical protein 0.0145 0.0507 0.1399
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0591 0.2778 0.7875
Leishmania major hypothetical protein, conserved 0.0145 0.0507 0.1399
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0156 0.0559 0.1133
Schistosoma mansoni calpain-7 (C02 family) 0.0503 0.233 0.233
Plasmodium falciparum serine repeat antigen 4 0.0156 0.0559 0.1464
Echinococcus multilocularis centrin 2 0.0081 0.0178 0.0178
Echinococcus granulosus calpain 5 0.0503 0.233 0.233
Trypanosoma brucei mitochondrial calcium uptake 1 0.0081 0.0178 0.0449

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Antifungal activity against Candida albicans at 200 ug/ml ChEMBL. 18603332
MIC (functional) = 25 ug ml-1 Antibacterial activity against Escherichia coli MTCC 722 after 24 hrs by NCCLS M7-A5 method ChEMBL. 18603332

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.