Detailed information for compound 1291868

Basic information

Technical information
  • TDR Targets ID: 1291868
  • Name: 3-(2,1,3-benzothiadiazol-7-ylsulfonylamino)-N -(2-ethoxyphenyl)propanamide
  • MW: 406.479 | Formula: C17H18N4O4S2
  • H donors: 2 H acceptors: 5 LogP: 1.9 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccccc1NC(=O)CCNS(=O)(=O)c1cccc2c1nsn2
  • InChi: 1S/C17H18N4O4S2/c1-2-25-14-8-4-3-6-12(14)19-16(22)10-11-18-27(23,24)15-9-5-7-13-17(15)21-26-20-13/h3-9,18H,2,10-11H2,1H3,(H,19,22)
  • InChiKey: HMJZZDGWXPGCRH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-ethoxyphenyl)-3-(piazthiol-4-ylsulfonylamino)propionamide
  • EU-0088318

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Brugia malayi EGF-like domain containing protein 0.0017 0.0054 0.0054
Echinococcus granulosus neurocalcin 0.0035 0.0205 0.0205
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Plasmodium vivax unspecified product 0.012 0.0933 0.2202
Toxoplasma gondii ABC1 family protein 0.0036 0.0212 0.0479
Brugia malayi cytochrome P450 0.0021 0.0083 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Entamoeba histolytica papain family cysteine protease domain containing protein 0.012 0.0933 0.2202
Trichomonas vaginalis calcium binding protein, putative 0.0035 0.0205 0.0484
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0131 0.0131
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.2102 0.2102
Leishmania major oligopeptidase b 0.021 0.1698 0.3847
Echinococcus granulosus cathepsin L 0.0277 0.2271 0.2271
Plasmodium falciparum proteasome subunit beta type-5 0.0083 0.0613 0.1447
Loa Loa (eye worm) hypothetical protein 0.012 0.0933 0.0933
Brugia malayi cathepsin F-like cysteine proteinase 0.0156 0.1243 0.1243
Onchocerca volvulus 0.0213 0.1724 0.3906
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0083 0.0031
Loa Loa (eye worm) hypothetical protein 0.012 0.0933 0.0933
Plasmodium vivax unspecified product 0.0156 0.1243 0.2937
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Entamoeba histolytica cysteine proteinase 1, putative 0.0277 0.2271 0.5364
Trypanosoma brucei Component of motile flagella 41 0.0035 0.0205 0.0464
Giardia lamblia Cathepsin B precursor 0.012 0.0933 0.2495
Toxoplasma gondii cathepsin B 0.0448 0.3737 0.8464
Echinococcus multilocularis Transglutaminase 0.0107 0.0816 0.0816
Brugia malayi hypothetical protein 0.0016 0.0042 0.0042
Giardia lamblia Cathepsin L-like protease 0.012 0.0933 0.2495
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0191 0.0191
Schistosoma mansoni cpg binding protein 0.003 0.016 0.016
Echinococcus multilocularis acylamino acid releasing enzyme 0.0055 0.0378 0.0378
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0131 0.0131
Onchocerca volvulus Cathepsin L homolog 0.0506 0.4234 0.9591
Schistosoma mansoni calpain-7 (C02 family) 0.026 0.2127 0.2127
Loa Loa (eye worm) hypothetical protein 0.012 0.0933 0.0933
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0083 0.0613 0.0613
Schistosoma mansoni cell polarity protein 0.0017 0.0054 0.0054
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.012 0.0933 0.2202
Schistosoma mansoni hypothetical protein 0.0017 0.0054 0.0054
Plasmodium falciparum cysteine proteinase falcipain 1 0.0277 0.2271 0.5364
Plasmodium falciparum serine repeat antigen 5 0.012 0.0933 0.2202
Echinococcus multilocularis cysteine protease 0.0506 0.4234 0.4234
Plasmodium falciparum cysteine proteinase falcipain 3 0.0506 0.4234 1
Brugia malayi Cathepsin L-like precursor 0.0506 0.4234 0.4234
Echinococcus granulosus proteasome prosome macropain 0.0083 0.0613 0.0613
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.008 0.008
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0098 0.0098
Mycobacterium leprae Probable lipase LipE 0.0036 0.0212 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0348 0.0348
Giardia lamblia Cathepsin L precursor 0.012 0.0933 0.2495
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Loa Loa (eye worm) hypothetical protein 0.0156 0.1243 0.1243
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.012 0.0933 0.2495
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0306 0.0306
Loa Loa (eye worm) MBCTL1 0.0053 0.0361 0.0361
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0033 0.0191 0.0191
Brugia malayi EF hand family protein 0.0035 0.0207 0.0207
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0083 0.0031
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0306 0.0306
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Trypanosoma brucei calpain-like protein, putative 0.0257 0.2102 0.476
Brugia malayi calpain family protein 1 0.0694 0.5841 0.5841
Trypanosoma cruzi prolyl endopeptidase 0.0527 0.4415 0.4415
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0277 0.2271 0.5144
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0044 0.0044
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0083 0.0031
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0613 0.0613
Trypanosoma cruzi cysteine proteinase, putative 0.0277 0.2271 0.2271
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0062 0.0062
Trypanosoma cruzi kinesin, putative 0.0185 0.1489 0.1489
Brugia malayi EGF-like domain containing protein 0.0017 0.0054 0.0054
Brugia malayi Cadherin domain containing protein 0.0017 0.0054 0.0054
Trichomonas vaginalis calmodulin-2, putative 0.0035 0.0205 0.0484
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0117 0.0275
Loa Loa (eye worm) Notch2 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0212 0.0212
Echinococcus granulosus protein jagged 1 0.0017 0.0054 0.0054
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0035 0.0205 0.0205
Loa Loa (eye worm) calpain family protein 1 0.0694 0.5841 0.5841
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0361 0.0361
Trichomonas vaginalis calmodulin, putative 0.0035 0.0205 0.0484
Echinococcus multilocularis neurocalcin 0.0035 0.0205 0.0205
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Schistosoma mansoni smad 0.0016 0.0044 0.0044
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0002 0.0002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0131 0.0131
Trypanosoma brucei calpain, putative 0.0072 0.0517 0.1172
Trichomonas vaginalis calpain, putative 0.0072 0.0517 0.1222
Brugia malayi EGF-like domain containing protein 0.0017 0.0054 0.0054
Schistosoma mansoni neuronal calcium sensor 0.0035 0.0205 0.0205
Echinococcus multilocularis 0.0021 0.0083 0.0083
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0035 0.0207 0.0207
Schistosoma mansoni mitochondrial solute carrier 0.0035 0.0205 0.0205
Echinococcus multilocularis calcium uptake protein 1 0.0035 0.0207 0.0207
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.012 0.0933 0.2202
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0083 0.0083
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0349 0.2896 0.2896
Echinococcus granulosus slit 2 protein 0.0017 0.0054 0.0054
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.021 0.1698 0.24
Onchocerca volvulus 0.0035 0.0205 0.0464
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0349 0.2896 0.2896
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0348 0.0821
Entamoeba histolytica cysteine proteinase, putative 0.0506 0.4234 1
Trypanosoma cruzi cysteine peptidase, putative 0.0156 0.1243 0.1243
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.07 0.07
Echinococcus multilocularis calpain 7 (C02 family) 0.0257 0.2102 0.2102
Echinococcus multilocularis slit 2 protein 0.0017 0.0054 0.0054
Onchocerca volvulus 0.0017 0.0054 0.0123
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.021 0.1698 0.2423
Echinococcus multilocularis hypothetical protein 0.0257 0.2102 0.2102
Brugia malayi MH2 domain containing protein 0.0016 0.0044 0.0044
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.1516 0.1516
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0324 0.0324
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0164 0.0164
Schistosoma mansoni calpain (C02 family) 0.0257 0.2102 0.2102
Leishmania major calmodulin-like protein 0.0035 0.0205 0.0464
Trichomonas vaginalis calmodulin, putative 0.0035 0.0205 0.0484
Plasmodium falciparum serine repeat antigen 6 0.012 0.0933 0.2202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0527 0.4415 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0131 0.0131
Brugia malayi Muscle positioning protein 4 0.0017 0.0054 0.0054
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0361 0.0361
Entamoeba histolytica cysteine proteinase 2 0.0277 0.2271 0.5364
Plasmodium falciparum peptidase, putative 0.0055 0.0378 0.0893
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0378 0.0378
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.021 0.1698 0.1698
Plasmodium falciparum serine repeat antigen 4 0.012 0.0933 0.2202
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0517 0.1222
Schistosoma mansoni hypothetical protein 0.0035 0.0205 0.0205
Brugia malayi Muscleblind-like protein 0.018 0.1449 0.1449
Mycobacterium ulcerans hypothetical protein 0.0107 0.0816 0.1117
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0017 0.0054 0.0054
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0506 0.4234 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0072 0.0517 0.0517
Echinococcus granulosus calumenin 0.0035 0.0207 0.0207
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Toxoplasma gondii prolyl endopeptidase 0.0527 0.4415 1
Onchocerca volvulus 0.0035 0.0207 0.0469
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.008 0.0182
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.2102
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0324 0.0324
Echinococcus multilocularis programmed cell death protein 0.0039 0.0235 0.0235
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.1683 0.1683
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0054 0.0054
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0062 0.0062
Onchocerca volvulus 0.0213 0.1724 0.3906
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Loa Loa (eye worm) EF hand family protein 0.0035 0.0205 0.0205
Plasmodium falciparum importin beta, putative 0.0028 0.0143 0.0338
Onchocerca volvulus Peroxidase homolog 0.0213 0.1724 0.3906
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0324 0.0324
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Loa Loa (eye worm) hypothetical protein 0.0049 0.0324 0.0324
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0072 0.0517 0.0517
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0378 0.0378
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0055 0.0378 0.0856
Trypanosoma brucei caltractin, putative 0.0039 0.0235 0.0532
Schistosoma mansoni peroxidasin 0.0213 0.1724 0.1724
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0277 0.2271 0.2271
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Brugia malayi MH1 domain containing protein 0.0016 0.0044 0.0044
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.476
Brugia malayi Calmodulin-like protein 0.0035 0.0205 0.0205
Loa Loa (eye worm) Smad1 0.0016 0.0044 0.0044
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0055 0.0378 0.0856
Brugia malayi MAP kinase sur-1 0.0052 0.0348 0.0348
Trypanosoma brucei protein I/6 0.0035 0.0205 0.0464
Mycobacterium ulcerans lipase LipD 0.0036 0.0212 0.0221
Loa Loa (eye worm) hypothetical protein 0.0055 0.0378 0.0378
Brugia malayi Animal haem peroxidase family protein 0.0213 0.1724 0.1724
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0348 0.0931
Plasmodium vivax serine-repeat antigen (SERA), putative 0.012 0.0933 0.2202
Echinococcus multilocularis smad 0.0016 0.0044 0.0044
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0062 0.0148
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0212 0.0221
Toxoplasma gondii EF hand domain-containing protein 0.0035 0.0205 0.0464
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0072 0.0517 0.1172
Schistosoma mansoni calpain C (C02 family) 0.0257 0.2102 0.2102
Schistosoma mansoni hypothetical protein 0.0166 0.1329 0.1329
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0055 0.0378 0.0378
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0348 0.0348
Trichomonas vaginalis calmodulin, putative 0.0035 0.0205 0.0484
Schistosoma mansoni hypothetical protein 0.0017 0.0054 0.0054
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.2102 0.2102
Echinococcus granulosus Transglutaminase 0.0107 0.0816 0.0816
Plasmodium vivax centrin-1, putative 0.0035 0.0205 0.0484
Trichomonas vaginalis calmodulin, putative 0.0035 0.0207 0.0489
Loa Loa (eye worm) hypothetical protein 0.018 0.1449 0.1449
Brugia malayi cathepsin Z-like cysteine proteinase 0.012 0.0933 0.0933
Echinococcus multilocularis cathepsin L cysteine protease 0.0506 0.4234 0.4234
Echinococcus granulosus EF hand domain containing family member A2 0.0035 0.0205 0.0205
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0083 0.0031
Loa Loa (eye worm) prolyl oligopeptidase 0.0055 0.0378 0.0378
Brugia malayi Cytochrome P450 family protein 0.0038 0.0231 0.0231
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.1947 0.1947
Echinococcus multilocularis calmodulin 0.0035 0.0205 0.0205
Echinococcus granulosus notch 0.0017 0.0054 0.0054
Schistosoma mansoni gabp alpha 0.0079 0.0577 0.0577
Echinococcus multilocularis neurogenic locus notch protein 4 0.0017 0.0054 0.0054
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0146 0.0146
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0143 0.0143
Giardia lamblia Cathepsin L-like protease 0.012 0.0933 0.2495
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0933 0.2495
Trypanosoma brucei centrin, putative 0.0035 0.0205 0.0464
Echinococcus multilocularis ets variant gene 4 0.0011 0.0002 0.0002
Loa Loa (eye worm) fibroinase 0.0506 0.4234 0.4234
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0348 0.0821
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0277 0.2271 0.2271
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0816 0.1117
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0506 0.4234 0.4234
Onchocerca volvulus 0.0017 0.0054 0.0123
Entamoeba histolytica calcium-binding protein, putative 0.0035 0.0205 0.0484
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Echinococcus multilocularis muscleblind protein 1 0.018 0.1449 0.1449
Entamoeba histolytica cysteine proteinase, putative 0.0277 0.2271 0.5364
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0072 0.0517 0.1172
Echinococcus granulosus calmodulin 0.0035 0.0205 0.0205
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0349 0.2896 0.6839
Mycobacterium ulcerans beta-lactamase 0.0036 0.0212 0.0221
Echinococcus multilocularis centrin 2 0.0035 0.0205 0.0205
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0306 0.0306
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0072 0.0517 0.1222
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0212 0.05
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0062 0.0062
Echinococcus granulosus calbindin 32 0.0035 0.0207 0.0207
Loa Loa (eye worm) notch protein 0.0017 0.0054 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0083 0.0031
Schistosoma mansoni reticulocalbin 0.0035 0.0207 0.0207
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.07 0.07
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0348 0.0821
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Entamoeba histolytica cysteine protease, putative 0.012 0.0933 0.2202
Leishmania major phospholipase c-like protein 0.0035 0.0205 0.0464
Giardia lamblia Encystation-specific protease 0.012 0.0933 0.2495
Plasmodium vivax vivapain-2 0.0506 0.4234 1
Onchocerca volvulus 0.012 0.0933 0.2112
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0083 0.0083
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.1947 0.1947
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.015 0.015
Brugia malayi GCC2 and GCC3 family protein 0.0017 0.0054 0.0054
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.012 0.0933 0.2202
Trypanosoma cruzi cruzipain precursor, putative 0.0156 0.1243 0.1243
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Entamoeba histolytica hypothetical protein 0.0023 0.0098 0.0232
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0062 0.0062
Brugia malayi programmed cell death protein 6 0.0035 0.0205 0.0205
Echinococcus granulosus neurogenic locus notch protein 0.0017 0.0054 0.0054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.07 0.07
Giardia lamblia Hypothetical protein 0.0107 0.0816 0.2185
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0072 0.0517 0.0517
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0083 0.0031
Echinococcus granulosus cathepsin l1 0.0349 0.2896 0.2896
Schistosoma mansoni ef hand domain family member A2 0.0035 0.0205 0.0205
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0083 0.0613 0.1447
Echinococcus multilocularis calpain A 0.0729 0.6144 0.6144
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0002
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0212 0.0191
Schistosoma mansoni smad1 5 8 and 0.0016 0.0044 0.0044
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0026 0.0026
Schistosoma mansoni calmodulin 0.0035 0.0205 0.0205
Brugia malayi MH1 domain containing protein 0.0016 0.0044 0.0044
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.1516 0.1516
Mycobacterium ulcerans proteasome PrcA 0.0807 0.6813 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0014 0.0014
Brugia malayi Pre-SET motif family protein 0.003 0.0164 0.0164
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.2102 0.2102
Trypanosoma brucei Calpain-like protein 2 0.0072 0.0517 0.1172
Onchocerca volvulus 0.0506 0.4234 0.9591
Trichomonas vaginalis calpain, putative 0.0072 0.0517 0.1222
Leishmania major protein kinase, putative 0.0036 0.0209 0.0473
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0231 0.0231
Loa Loa (eye worm) papain family cysteine protease containing protein 0.012 0.0933 0.0933
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0348 0.0788
Trypanosoma brucei calpain-like protein, putative 0.0257 0.2102 0.476
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0361 0.0361
Brugia malayi Blistered cuticle protein 3 0.0213 0.1724 0.1724
Brugia malayi Cathepsin L-like cysteine proteinase 0.0349 0.2896 0.2896
Trypanosoma cruzi major cysteine proteinase, putative 0.012 0.0933 0.0933
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0035 0.0205 0.0484
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0002 0.0002
Echinococcus granulosus protein jagged 1 0.0017 0.0054 0.0054
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0378 0.0378
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.012 0.0933 0.2202
Toxoplasma gondii cathepsin CPC1 0.012 0.0933 0.2112
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0083 0.0188
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0694 0.5841 0.5841
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.07 0.07
Echinococcus granulosus EF hand domain containing family member A2 0.0035 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0506 0.4234 1
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Plasmodium falciparum flap endonuclease 1 0.0026 0.0127 0.0299
Leishmania major cytochrome p450-like protein 0.0021 0.0083 0.0188
Schistosoma mansoni hypothetical protein 0.0166 0.1329 0.1329
Mycobacterium tuberculosis Probable peptidase 0.021 0.1698 0.2423
Echinococcus granulosus cathepsin L 0.012 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.012 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Schistosoma mansoni ets 0.0011 0.0002 0.0002
Trypanosoma cruzi centrin-3 0.0039 0.0235 0.0235
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Trichomonas vaginalis calcium binding protein, putative 0.0035 0.0205 0.0484
Mycobacterium ulcerans hypothetical protein 0.0107 0.0816 0.1117
Loa Loa (eye worm) cytochrome P450 0.0021 0.0083 0.0083
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0212 0.0212
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0062 0.0167
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0231 0.0231
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0127 0.0339
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0527 0.4415 0.4415
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0212 0.0212
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0205 0.0464
Brugia malayi hypothetical protein 0.0213 0.1724 0.1724
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0348 0.0348
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Echinococcus multilocularis proteasome (prosome, macropain) 0.0083 0.0613 0.0613
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0156 0.1243 0.1243
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0349 0.2896 0.2896
Trypanosoma brucei cysteine peptidase C (CPC) 0.0448 0.3737 0.8464
Echinococcus granulosus protein jagged 2 0.0017 0.0054 0.0054
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0062 0.0062
Echinococcus multilocularis prolyl endopeptidase 0.0527 0.4415 0.4415
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0212 0.0221
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.008 0.008
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0212 0.0221
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0062 0.5
Mycobacterium tuberculosis Long conserved protein 0.0107 0.0816 0.1117
Schistosoma mansoni cathepsin F (C01 family) 0.0506 0.4234 0.4234
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0277 0.2271 0.5144
Mycobacterium tuberculosis Conserved protein 0.0107 0.0816 0.1117
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Brugia malayi Proteasome A-type and B-type family protein 0.0083 0.0613 0.0613
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0072 0.0517 0.1222
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0729 0.6142 0.6142
Schistosoma mansoni notch 0.0017 0.0054 0.0054
Mycobacterium ulcerans putative transglutaminase-like protein 0.0107 0.0816 0.1117
Toxoplasma gondii hypothetical protein 0.0072 0.0517 0.1172
Schistosoma mansoni cpg binding protein 0.0028 0.0146 0.0146
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.008 0.0215
Echinococcus multilocularis neurogenic locus protein delta 0.0017 0.0054 0.0054
Onchocerca volvulus 0.0017 0.0054 0.0123
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.2102 0.2102
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0002 0.0002
Plasmodium falciparum serine repeat antigen 9 0.012 0.0933 0.2202
Brugia malayi Papain family cysteine protease containing protein 0.0506 0.4234 0.4234
Schistosoma mansoni lamin 0.0026 0.0131 0.0131
Loa Loa (eye worm) ctsf protein 0.0506 0.4234 0.4234
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0426 0.0426
Entamoeba histolytica prolyl oligopeptidase family protein 0.0055 0.0378 0.0893
Onchocerca volvulus 0.0506 0.4234 0.9591
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Echinococcus multilocularis cathepsin L cysteine protease 0.0506 0.4234 0.4234
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.012 0.0933 0.2202
Echinococcus granulosus neurogenic locus protein delta 0.0017 0.0054 0.0054
Brugia malayi Peroxidasin 0.0213 0.1724 0.1724
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0083 0.0031
Trichomonas vaginalis calmodulin, putative 0.0039 0.0235 0.0554
Trypanosoma cruzi cruzipain precursor, putative 0.0506 0.4234 0.4234
Brugia malayi MH2 domain containing protein 0.0239 0.1947 0.1947
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0083 0.0031
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0156 0.1243 0.1243
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0506 0.4234 0.4234
Onchocerca volvulus Peroxidasin homolog 0.0213 0.1724 0.3906
Leishmania major centrin, putative 0.0035 0.0205 0.0464
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0083 0.0031
Brugia malayi notch-like transmembrane receptor 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0349 0.2896 0.2896
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.012 0.0933 0.2202
Trypanosoma cruzi I/6 autoantigen, putative 0.0035 0.0205 0.0205
Trypanosoma brucei kinesin, putative 0.0185 0.1489 0.3373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0506 0.4234 0.4234
Trichomonas vaginalis calpain, putative 0.0072 0.0517 0.1222
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.1865 0.267
Schistosoma mansoni centrin-related 0.0035 0.0205 0.0205
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0348 0.0348
Entamoeba histolytica calmodulin, putative 0.0035 0.0205 0.0484
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0212 0.0212
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0212 0.05
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0062 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0506 0.4234 1
Trypanosoma brucei oligopeptidase b 0.021 0.1698 0.3847
Echinococcus granulosus GPCR family 2 0.0015 0.0037 0.0037
Entamoeba histolytica calpain family cysteine protease, putative 0.0072 0.0517 0.1222
Plasmodium vivax vivapain-2 0.0506 0.4234 1
Echinococcus granulosus GA binding protein alpha chain 0.0079 0.0577 0.0577
Echinococcus multilocularis protein jagged 1 0.0017 0.0054 0.0054
Leishmania major importin beta-1 subunit, putative 0.0023 0.0098 0.0222
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0083 0.0031
Brugia malayi transcription factor E74 isoform 0.0011 0.0002 0.0002
Trypanosoma brucei calpain-like protein, putative 0.0257 0.2102 0.476
Schistosoma mansoni ets-related 0.0238 0.1946 0.1946
Leishmania major calmodulin, putative 0.0035 0.0205 0.0464
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0933 0.0933
Onchocerca volvulus Cathepsin L homolog 0.012 0.0933 0.2112
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.07 0.07
Trichomonas vaginalis peptide N-glycanase, putative 0.0107 0.0816 0.1928
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.2102
Trichomonas vaginalis esterase, putative 0.0036 0.0212 0.05
Schistosoma mansoni cathepsin C 0.012 0.0933 0.0933
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0083 0.0031
Brugia malayi cathepsin Z-like cysteine proteinase 0.012 0.0933 0.0933
Brugia malayi EGF-like domain containing protein 0.0017 0.0054 0.0054
Giardia lamblia Cathepsin B precursor 0.012 0.0933 0.2495
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.07 0.07
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0378 0.0893
Echinococcus multilocularis calmodulin 0.0035 0.0205 0.0205
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0055 0.0378 0.0856
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.021 0.1698 0.2423
Trypanosoma cruzi cysteine peptidase, putative 0.0277 0.2271 0.2271
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Brugia malayi Cytochrome P450 family protein 0.0021 0.0083 0.0083
Onchocerca volvulus 0.0017 0.0054 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0933 0.2202
Toxoplasma gondii centrin 0.0035 0.0205 0.0464
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0506 0.4234 0.4234
Brugia malayi Cytochrome P450 family protein 0.0038 0.0231 0.0231
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Echinococcus multilocularis calpain 0.0257 0.2102 0.2102
Loa Loa (eye worm) hypothetical protein 0.0622 0.5229 0.5229
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0055 0.0378 0.0893
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0933 0.2202
Schistosoma mansoni notch 0.0017 0.0054 0.0054
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0127 0.0287
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Giardia lamblia High cysteine protein 0.0017 0.0054 0.0146
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0212 0.0221
Schistosoma mansoni gamma-secretase subunit aph-1 0.0734 0.619 0.619
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0072 0.0517 0.1172
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0143 0.0325
Schistosoma mansoni hypothetical protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) animal heme peroxidase 0.0213 0.1724 0.1724
Onchocerca volvulus Slit protein homolog 0.0017 0.0054 0.0123
Plasmodium falciparum serine repeat antigen 7 0.012 0.0933 0.2202
Echinococcus granulosus peroxidasin 0.0213 0.1724 0.1724
Brugia malayi cahepsin L-like non-peptiedase homolog 0.012 0.0933 0.0933
Schistosoma mansoni calpain-7 (C02 family) 0.026 0.2127 0.2127
Giardia lamblia Transglutaminase/protease, putative 0.0107 0.0816 0.2185
Loa Loa (eye worm) animal heme peroxidase 0.0213 0.1724 0.1724
Trypanosoma brucei hypothetical protein 0.0072 0.0517 0.1172
Giardia lamblia Cathepsin B precursor 0.012 0.0933 0.2495
Giardia lamblia Cysteine protease 0.012 0.0933 0.2495
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0072 0.0517 0.0517
Toxoplasma gondii hypothetical protein 0.0055 0.0378 0.0856
Loa Loa (eye worm) hypothetical protein 0.0156 0.1243 0.1243
Echinococcus multilocularis cathepsin L 0.012 0.0933 0.0933
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0083 0.0031
Trichomonas vaginalis calcium binding protein, putative 0.0039 0.0235 0.0554
Brugia malayi MH2 domain containing protein 0.0016 0.0044 0.0044
Loa Loa (eye worm) animal heme peroxidase 0.0213 0.1724 0.1724
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0933 0.2202
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0035 0.0205 0.0205
Loa Loa (eye worm) calpain 0.0257 0.2102 0.2102
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0807 0.6813 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0506 0.4234 0.4234
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.012 0.0933 0.0933
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0117 0.0264
Mycobacterium tuberculosis Conserved protein 0.0036 0.0212 0.0221
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0083 0.0031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.2102
Loa Loa (eye worm) hypothetical protein 0.0035 0.0205 0.0205
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0062 0.0148
Brugia malayi fibroinase precursor 0.012 0.0933 0.0933
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.012 0.0933 0.2202
Echinococcus multilocularis calbindin 32 0.0035 0.0207 0.0207
Trypanosoma brucei calpain, putative 0.0072 0.0517 0.1172
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.008 0.008
Leishmania major hypothetical protein, conserved 0.0035 0.0207 0.0469
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0933 0.2202
Echinococcus granulosus cysteine protease 0.0277 0.2271 0.2271
Loa Loa (eye worm) cathepsin B 0.0448 0.3737 0.3737
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0306 0.0692
Schistosoma mansoni Smad4 0.0016 0.0044 0.0044
Schistosoma mansoni cpg binding protein 0.003 0.016 0.016
Schistosoma mansoni calmodulin 0.0035 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Schistosoma mansoni cathepsin F (C01 family) 0.0506 0.4234 0.4234
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0072 0.0517 0.0517
Echinococcus multilocularis peroxidasin 0.0213 0.1724 0.1724
Loa Loa (eye worm) cysteine protease 0.0506 0.4234 0.4234
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0036 0.0209 0.0209
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0017 0.0054 0.0123
Entamoeba histolytica cysteine protease, putative 0.012 0.0933 0.2202
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) blistered cuticle protein 3 0.0213 0.1724 0.1724
Trypanosoma cruzi centrin, putative 0.0039 0.0235 0.0235
Brugia malayi Pre-SET motif family protein 0.0208 0.1683 0.1683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0933 0.2202
Mycobacterium ulcerans hypothetical protein 0.0036 0.0212 0.0221
Onchocerca volvulus Cathepsin F homolog 0.0506 0.4234 0.9591
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0083 0.0083
Echinococcus granulosus intermediate filament protein 0.0026 0.0131 0.0131
Echinococcus multilocularis neuronal calcium sensor 0.0035 0.0205 0.0205
Giardia lamblia Cathepsin L precursor 0.012 0.0933 0.2495
Echinococcus multilocularis EF hand domain containing family member A2 0.0035 0.0207 0.0207
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0083 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0933 0.2202
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0933 0.0933
Trichomonas vaginalis hypothetical protein 0.0072 0.0517 0.1222
Brugia malayi RNA, U transporter 1 0.0079 0.0583 0.0583
Mycobacterium ulcerans transglutaminase family protein 0.0107 0.0816 0.1117
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.476
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0933 0.0933
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0072 0.0517 0.0517
Loa Loa (eye worm) hypothetical protein 0.0026 0.0127 0.0127
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0212 0.0221
Loa Loa (eye worm) hypothetical protein 0.012 0.0933 0.0933
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0062 1
Leishmania major proteasome beta 5 subunit, putative 0.0083 0.0613 0.1388
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0035 0.0205 0.0205
Entamoeba histolytica calcium binding family protein 0.0035 0.0205 0.0484
Schistosoma mansoni smad1 5 8 and 0.0016 0.0044 0.0044
Trichomonas vaginalis set domain proteins, putative 0.0236 0.1927 0.4552
Brugia malayi Animal haem peroxidase family protein 0.0213 0.1724 0.1724
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0083 0.0031
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0014 0.0014
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0348 0.0788
Loa Loa (eye worm) calpain family protein 1 0.0509 0.4257 0.4257
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Brugia malayi calpain 7 0.0257 0.2102 0.2102
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0164 0.0164
Brugia malayi CXXC zinc finger family protein 0.0028 0.0146 0.0146
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0079 0.0577 0.0577
Brugia malayi EGF-like domain containing protein 0.0017 0.0054 0.0054
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0083 0.0031
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Toxoplasma gondii cathepsin CPL 0.0506 0.4234 0.9591
Plasmodium vivax calpain, putative 0.0257 0.2102 0.4963
Echinococcus multilocularis neurogenic locus protein delta 0.0017 0.0054 0.0054
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Trichomonas vaginalis ran, putative 0.0021 0.008 0.019
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0037 0.0037
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0035 0.0205 0.0205
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0734 0.619 0.619
Echinococcus multilocularis fat cadherin tumor suppressor 0.0017 0.0054 0.0054
Leishmania major cytochrome p450-like protein 0.0038 0.0231 0.0523
Onchocerca volvulus Neurogenic locus notch homolog 0.0017 0.0054 0.0123
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Mycobacterium leprae Conserved hypothetical protein 0.0107 0.0816 0.109
Brugia malayi intermediate filament protein 0.0026 0.0131 0.0131
Trichomonas vaginalis centrin, putative 0.0035 0.0205 0.0484
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0348 0.0348
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0127 0.0299
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0055 0.0378 0.0378
Toxoplasma gondii exonuclease III APE 0.0018 0.0062 0.0142
Echinococcus multilocularis protein C ets 2 0.0011 0.0002 0.0002
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0083 0.0188
Trypanosoma cruzi Aph-1 protein, putative 0.0286 0.2354 0.2354
Toxoplasma gondii preprocathepsin c precursor, putative 0.012 0.0933 0.2112
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0083 0.0031
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0062 0.0142
Brugia malayi Cathepsin L-like precursor 0.0506 0.4234 0.4234
Giardia lamblia Cathepsin B precursor 0.012 0.0933 0.2495
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0055 0.0378 0.0378
Echinococcus granulosus neuronal calcium sensor 0.0035 0.0205 0.0205
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0117 0.0117
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0083 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0933 0.2202
Onchocerca volvulus 0.0437 0.3645 0.8255
Entamoeba histolytica calmodulin, putative 0.0035 0.0205 0.0484
Giardia lamblia Cysteine protease 0.012 0.0933 0.2495
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0002 0.0002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0212 0.0212
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0933 0.0933
Echinococcus granulosus EF HAND 1 calcium binding site 0.0035 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Echinococcus granulosus flap endonuclease 1 0.0026 0.0127 0.0127
Echinococcus multilocularis neurogenic locus notch protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0035 0.0205 0.0205
Onchocerca volvulus 0.0026 0.0131 0.0298
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0072 0.0517 0.0517
Echinococcus granulosus cathepsin L cysteine proteinase 0.0506 0.4234 0.4234
Toxoplasma gondii calcium-dependent protein kinase 0.0036 0.0211 0.0478
Echinococcus granulosus snurportin 1 0.0297 0.245 0.245
Schistosoma mansoni lamin 0.0026 0.0131 0.0131
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0212 0.05
Loa Loa (eye worm) hypothetical protein 0.018 0.1449 0.1449
Brugia malayi Cadherin domain containing protein 0.0017 0.0054 0.0054
Onchocerca volvulus 0.0349 0.2896 0.6559
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0472 0.3942 0.5747
Brugia malayi calpain 5 0.0072 0.0517 0.0517
Echinococcus granulosus smad 0.0016 0.0044 0.0044
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0002 0.0002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0297 0.245 0.245
Loa Loa (eye worm) programmed cell death protein 6 0.0035 0.0207 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0205 0.0484
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0083 0.0031
Leishmania major cysteine peptidase A (CPA) 0.0506 0.4234 0.9591
Toxoplasma gondii EFHC1, putative 0.0035 0.0205 0.0464
Trichomonas vaginalis calmodulin, putative 0.0035 0.0205 0.0484
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0083 0.0031
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Echinococcus granulosus delta-like protein 1 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0055 0.0378 0.0378
Brugia malayi gamma-secretase subunit aph-1 0.0734 0.619 0.619
Echinococcus multilocularis cpg binding protein 0.003 0.016 0.016
Giardia lamblia Alanyl dipeptidyl peptidase 0.0055 0.0378 0.1011
Loa Loa (eye worm) calpain 5 0.0185 0.1489 0.1489
Schistosoma mansoni cathepsin s 0.0156 0.1243 0.1243
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.012 0.0933 0.2202
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0083 0.0031
Giardia lamblia Cathepsin L precursor 0.012 0.0933 0.2495
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0083 0.0031
Schistosoma mansoni Mername-AA248 (C02 family) 0.0257 0.2102 0.2102
Brugia malayi Ets-domain containing protein 0.0079 0.0577 0.0577
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0127 0.0127
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0371 0.0841
Loa Loa (eye worm) hypothetical protein 0.0028 0.0143 0.0143
Echinococcus granulosus geminin 0.0166 0.1329 0.1329
Brugia malayi Ets-domain containing protein 0.0079 0.0577 0.0577
Brugia malayi calcium-binding protein 0.0035 0.0205 0.0205
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0117 0.0275
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0002 0.0002
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.008 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.2271 0.5364
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0448 0.3737 0.3737
Entamoeba histolytica calpain large subunit domain III containing protein 0.0185 0.1489 0.3517
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.012 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0044 0.0044
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0044 0.0044
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0035 0.0207 0.0207
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Schistosoma mansoni slit 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0212 0.0212
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.012 0.0933 0.2202
Trypanosoma cruzi cysteine peptidase, putative 0.0506 0.4234 0.4234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.2271 0.5364
Loa Loa (eye worm) hypothetical protein 0.0047 0.0306 0.0306
Giardia lamblia Hypothetical protein 0.0035 0.0207 0.0554
Entamoeba histolytica grainin 2 0.0039 0.0235 0.0554
Echinococcus multilocularis neural cadherin 0.0017 0.0054 0.0054
Giardia lamblia Alanyl dipeptidyl peptidase 0.0055 0.0378 0.1011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0053
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0448 0.3737 0.8464
Echinococcus granulosus cathepsin l1 0.0506 0.4234 0.4234
Loa Loa (eye worm) papain family cysteine protease containing protein 0.012 0.0933 0.0933
Echinococcus granulosus calpain 5 0.0257 0.2102 0.2102
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0035 0.0205 0.0205
Entamoeba histolytica cysteine proteinase, putative 0.0277 0.2271 0.5364
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0212 0.0221
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0055 0.0378 0.0378
Brugia malayi beta-lactamase family protein 0.0036 0.0212 0.0212
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Entamoeba histolytica hypothetical protein, conserved 0.0035 0.0207 0.0489
Trypanosoma brucei Calpain-like protein 1.2 0.0072 0.0517 0.1172
Schistosoma mansoni cathepsin B (C01 family) 0.012 0.0933 0.0933
Trypanosoma brucei Aph-1 protein, putative 0.0286 0.2354 0.5332
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0072 0.0517 0.1222
Brugia malayi Flap endonuclease-1 0.0026 0.0127 0.0127
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0212 0.0212
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0017 0.0054 0.0054
Brugia malayi Cathepsin L-like precursor 0.0506 0.4234 0.4234
Loa Loa (eye worm) hypothetical protein 0.012 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0378 0.0893
Trypanosoma cruzi oligopeptidase b 0.021 0.1698 0.1698
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0506 0.4234 0.4234
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0117 0.0117
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0277 0.2271 0.2271
Echinococcus granulosus calpain 7 C02 family 0.0257 0.2102 0.2102
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Onchocerca volvulus 0.0213 0.1724 0.3906
Loa Loa (eye worm) hypothetical protein 0.0053 0.0361 0.0361
Onchocerca volvulus 0.003 0.0164 0.0372
Plasmodium falciparum serine repeat antigen 1 0.012 0.0933 0.2202
Brugia malayi cathepsin L-like cysteine proteinase 0.012 0.0933 0.0933
Trypanosoma brucei Calpain-like protein 1.1 0.0072 0.0517 0.1172
Echinococcus multilocularis EF hand domain containing family member A2 0.0035 0.0205 0.0205
Leishmania major programmed cell death 6 protein-like protein 0.0035 0.0205 0.0464
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0212 0.0221
Trichomonas vaginalis myosin light chain 1, putative 0.0035 0.0205 0.0484
Echinococcus granulosus centrin 2 0.0035 0.0205 0.0205
Plasmodium vivax serine-repeat antigen (SERA) 0.012 0.0933 0.2202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Giardia lamblia Cathepsin L precursor 0.012 0.0933 0.2495
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0072 0.0517 0.0517
Brugia malayi Cathepsin L-like precursor 0.0506 0.4234 0.4234
Giardia lamblia Cathepsin L precursor 0.012 0.0933 0.2495
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0807 0.6815 0.6815
Brugia malayi Animal haem peroxidase family protein 0.0213 0.1724 0.1724
Toxoplasma gondii troponin c, isotype gamma, putative 0.0035 0.0205 0.0464
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.2102 0.2102
Schistosoma mansoni rab 0.0035 0.0205 0.0205
Plasmodium falciparum centrin-1 0.0035 0.0205 0.0484
Leishmania major kinesin, putative 0.0185 0.1489 0.3373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0002 0.0002
Onchocerca volvulus 0.0036 0.0212 0.0479
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0207 0.0489
Brugia malayi prolyl oligopeptidase family protein 0.0527 0.4415 0.4415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0933 0.2202
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0083 0.0031
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0055 0.0378 0.0893
Leishmania major calmodulin-like protein 0.0035 0.0205 0.0464
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0083 0.0613 0.0613
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Schistosoma mansoni ap endonuclease 0.0018 0.0062 0.0062
Leishmania major hypothetical protein, conserved 0.0036 0.0212 0.0479
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Schistosoma mansoni ap endonuclease 0.0018 0.0062 0.0062
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0037 0.0037
Echinococcus granulosus gamma secretase subunit aph 1 0.0734 0.619 0.619
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.012 0.0933 0.2202
Toxoplasma gondii centrin, putative 0.0035 0.0205 0.0464
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.07 0.07
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.021 0.1698 0.3847
Trichomonas vaginalis calmodulin, putative 0.0035 0.0205 0.0484
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0933 0.2495
Trypanosoma brucei prolyl endopeptidase 0.0527 0.4415 1
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0055 0.0378 0.0856
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.021 0.1698 0.1698
Schistosoma mansoni hypothetical protein 0.0017 0.0054 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0083 0.0031
Echinococcus multilocularis GA binding protein alpha chain 0.0079 0.0577 0.0577
Trypanosoma brucei antigen, putative 0.0257 0.2102 0.476
Trypanosoma cruzi cysteine peptidase, putative 0.0506 0.4234 0.4234
Plasmodium vivax SET domain protein, putative 0.003 0.0164 0.0388
Trypanosoma brucei I/6 autoantigen 0.0035 0.0205 0.0464
Trypanosoma cruzi oligopeptidase b 0.021 0.1698 0.1698
Brugia malayi Cathepsin L-like precursor 0.0349 0.2896 0.2896
Brugia malayi Smad1 0.0016 0.0044 0.0044
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0055 0.0378 0.0378
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0072 0.0517 0.0517
Schistosoma mansoni hypothetical protein 0.0072 0.0517 0.0517
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0067 0.048 0.048
Schistosoma mansoni peroxidasin 0.0213 0.1724 0.1724
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0143 0.0325
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.021 0.1698 0.3847
Onchocerca volvulus Peroxidase homolog 0.0213 0.1724 0.3906
Echinococcus granulosus protein jagged 2 0.0017 0.0054 0.0054
Trypanosoma brucei protein kinase, putative 0.0052 0.0348 0.0788
Leishmania major centrin, putative 0.0035 0.0205 0.0464
Schistosoma mansoni centrin 0.0035 0.0205 0.0205
Echinococcus multilocularis calpain 5 0.0257 0.2102 0.2102
Trypanosoma brucei cysteine peptidase, putative 0.0072 0.0517 0.1172
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0127 0.0127
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0036 0.0209 0.0473
Trypanosoma brucei mitochondrial calcium uptake 1 0.0035 0.0205 0.0464
Plasmodium falciparum serine repeat antigen 8 0.012 0.0933 0.2202
Onchocerca volvulus 0.0036 0.0212 0.0479
Trypanosoma cruzi major cysteine proteinase, putative 0.012 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0083 0.0031
Onchocerca volvulus 0.0506 0.4234 0.9591
Echinococcus multilocularis Smad4 0.0016 0.0044 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0083 0.0031
Entamoeba histolytica grainin, putative 0.0035 0.0207 0.0489
Plasmodium falciparum calpain 0.0072 0.0517 0.1222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0164 0.0164
Brugia malayi Thioredoxin family protein 0.0107 0.0816 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0933 0.2202
Echinococcus granulosus cathepsin L cysteine protease 0.0277 0.2271 0.2271
Giardia lamblia Cathepsin B precursor 0.012 0.0933 0.2495
Schistosoma mansoni notch 0.0017 0.0054 0.0054
Trypanosoma cruzi calmodulin, putative 0.0035 0.0205 0.0205
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0035 0.0205 0.0484
Mycobacterium tuberculosis Conserved protein 0.0036 0.0212 0.0221
Brugia malayi hypothetical protein 0.0025 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0036 0.0212 0.0212
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0055 0.0378 0.0378
Schistosoma mansoni calpain-2 (C02 family) 0.0072 0.0517 0.0517
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0083 0.0031
Onchocerca volvulus Prolyl endopeptidase homolog 0.0527 0.4415 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0083 0.0031
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0035 0.0205 0.0205
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0083 0.0031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.2102
Schistosoma mansoni cathepsin F (C01 family) 0.0349 0.2896 0.2896
Brugia malayi Delta serrate ligand family protein 0.0017 0.0054 0.0054
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.012 0.0933 0.2202
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0729 0.6142 0.6142
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0098 0.0232
Echinococcus multilocularis geminin 0.0166 0.1329 0.1329
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0306 0.0306
Entamoeba histolytica cysteine proteinase, putative 0.0506 0.4234 1
Onchocerca volvulus 0.0035 0.0205 0.0464
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0448 0.3737 0.8825
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Brugia malayi EF hand family protein 0.0035 0.0205 0.0205
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0055 0.0378 0.0856
Trypanosoma cruzi Aph-1 protein, putative 0.0286 0.2354 0.2354
Trichomonas vaginalis calcium binding protein, putative 0.0035 0.0205 0.0484
Mycobacterium leprae Conserved hypothetical protein 0.0107 0.0816 0.109
Brugia malayi Animal haem peroxidase family protein 0.0213 0.1724 0.1724
Schistosoma mansoni neuronal calcium sensor 0.0035 0.0205 0.0205
Entamoeba histolytica cysteine protease, putative 0.012 0.0933 0.2202
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0072 0.0517 0.1222
Echinococcus multilocularis cysteine protease 0.0506 0.4234 0.4234
Leishmania major hypothetical protein, conserved 0.0072 0.0517 0.1172
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.008 0.019
Echinococcus granulosus muscleblind protein 0.018 0.1449 0.1449
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.07 0.07
Leishmania major calpain protease-like protein 0.0072 0.0517 0.1172
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0002 0.0002
Onchocerca volvulus 0.0026 0.0131 0.0298
Echinococcus granulosus calpain A 0.0257 0.2102 0.2102
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0035 0.0205 0.0464
Schistosoma mansoni cathepsin S (C01 family) 0.012 0.0933 0.0933
Trypanosoma brucei prolyl oligopeptidase, putative 0.021 0.1698 0.3847
Brugia malayi EGF-like domain containing protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0156 0.1243 0.1243
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.012 0.0933 0.2202
Onchocerca volvulus Putative cubilin 0.0017 0.0054 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0164 0.0164
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0098 0.0232
Brugia malayi Animal haem peroxidase family protein 0.0213 0.1724 0.1724
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.012 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0062 0.0148
Echinococcus granulosus cpg binding protein 0.003 0.016 0.016
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0933 0.0933
Schistosoma mansoni smad1 5 8 and 0.0016 0.0044 0.0044
Brugia malayi calpain 5 0.0185 0.1489 0.1489
Entamoeba histolytica cysteine proteinase, putative 0.0349 0.2896 0.6839
Giardia lamblia Cysteine protease 0.012 0.0933 0.2495
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0002 0.0002
Loa Loa (eye worm) fli-1 protein 0.0238 0.1946 0.1946
Echinococcus granulosus neurogenic locus notch protein 4 0.0017 0.0054 0.0054
Entamoeba histolytica cysteine protease, putative 0.012 0.0933 0.2202
Plasmodium vivax unspecified product 0.0277 0.2271 0.5364
Plasmodium vivax serine-repeat antigen (SERA) 0.012 0.0933 0.2202
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0055 0.0378 0.0856
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0083 0.0613 0.0787
Brugia malayi Importin beta-1 subunit 0.0028 0.0143 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Onchocerca volvulus 0.0506 0.4234 0.9591
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0212 0.05
Loa Loa (eye worm) hypothetical protein 0.0694 0.5841 0.5841
Onchocerca volvulus 0.0036 0.0212 0.0479
Echinococcus multilocularis neurogenic locus notch protein 0.0017 0.0054 0.0054
Entamoeba histolytica cysteine protease, putative 0.0506 0.4234 1
Echinococcus multilocularis snurportin 1 0.0297 0.245 0.245
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Trypanosoma brucei calmodulin, putative 0.0035 0.0205 0.0464
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0072 0.0517 0.1172
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0036 0.0209 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0349 0.2896 0.6839
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Brugia malayi Cathepsin L-like precursor 0.0506 0.4234 0.4234
Echinococcus granulosus lamin 0.0026 0.0131 0.0131
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.008 0.008
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.2102 0.476
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0361 0.0361
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0083 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0348 0.0821
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Trypanosoma brucei centrin-3 0.0039 0.0235 0.0532
Trypanosoma brucei centrin, putative 0.0035 0.0205 0.0464
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0933 0.2202
Toxoplasma gondii calmodulin CAM1 0.0035 0.0207 0.0469
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0055 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.0037
Onchocerca volvulus 0.0017 0.0054 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0231 0.0523
Trichomonas vaginalis calmodulin, putative 0.0035 0.0205 0.0484
Leishmania major hypothetical protein, conserved 0.0035 0.0205 0.0464
Onchocerca volvulus Dual oxidase homolog 0.0213 0.1724 0.3906
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0037
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0231 0.0231
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.012 0.0933 0.0933
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0037 0.0037
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0933 0.2495
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Onchocerca volvulus 0.0107 0.0816 0.1849
Brugia malayi cathepsin L precursor 0.012 0.0933 0.0933
Brugia malayi Cytochrome P450 family protein 0.0077 0.0562 0.0562
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0037
Brugia malayi Papain family cysteine protease containing protein 0.0277 0.2271 0.2271
Brugia malayi mbt repeat family protein 0.0047 0.0306 0.0306
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Brugia malayi beta-lactamase 0.0036 0.0212 0.0212
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0062 0.0062
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0127 0.0299
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0306 0.0306
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0044 0.0044
Brugia malayi calpain family protein 1 0.0694 0.5841 0.5841
Giardia lamblia Cathepsin B precursor 0.0448 0.3737 1
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0002 0.0002
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0212 0.0221
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Brugia malayi Cathepsin L-like precursor 0.0156 0.1243 0.1243
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0213 0.1724 0.1724
Leishmania major calpain family cysteine protease-like protein 0.0072 0.0517 0.1172
Echinococcus granulosus protein C ets 2 0.0011 0.0002 0.0002
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0127 0.0287
Schistosoma mansoni hypothetical protein 0.0021 0.0083 0.0083
Echinococcus multilocularis protein jagged 2 0.0017 0.0054 0.0054
Trypanosoma cruzi cysteine peptidase, putative 0.0506 0.4234 0.4234
Entamoeba histolytica cysteine proteinase, putative 0.0277 0.2271 0.5364
Schistosoma mansoni notch 0.0017 0.0054 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0378 0.0378
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0083 0.0031
Trypanosoma brucei calmodulin, putative 0.0035 0.0207 0.0469
Schistosoma mansoni hypothetical protein 0.0107 0.0816 0.0816
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.008 0.008
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.0517
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0117 0.0275
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0083 0.0031
Schistosoma mansoni importin beta-1 0.0028 0.0143 0.0143
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Leishmania major calcineurin B subunit, putative 0.0035 0.0205 0.0464
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0212 0.0479
Loa Loa (eye worm) hypothetical protein 0.0025 0.0117 0.0117
Entamoeba histolytica cysteine protease, putative 0.012 0.0933 0.2202
Schistosoma mansoni neuronal calcium sensor 0.0035 0.0205 0.0205
Schistosoma mansoni ran 0.0021 0.008 0.008
Onchocerca volvulus Peroxidasin homolog 0.0213 0.1724 0.3906
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Echinococcus multilocularis protein jagged 1 0.0017 0.0054 0.0054
Brugia malayi EGF-like domain containing protein 0.0017 0.0054 0.0054
Schistosoma mansoni hypothetical protein 0.0017 0.0054 0.0054
Plasmodium vivax vivapain-1 0.0277 0.2271 0.5364
Entamoeba histolytica hypothetical protein 0.012 0.0933 0.2202
Leishmania major hypothetical protein, unknown function 0.0072 0.0517 0.1172
Leishmania major centrin, putative,caltractin, putative 0.0035 0.0205 0.0464
Schistosoma mansoni elf1 0.0011 0.0002 0.0002
Echinococcus granulosus neural cadherin 0.0017 0.0054 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0083 0.0031
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.012 0.0933 0.0933
Echinococcus granulosus Smad4 0.0016 0.0044 0.0044
Trypanosoma cruzi calmodulin, putative 0.0035 0.0205 0.0205
Trypanosoma cruzi cysteine proteinase, putative 0.0277 0.2271 0.2271
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0209 0.0493
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.4234 0.9591
Entamoeba histolytica cysteine protease, putative 0.012 0.0933 0.2202
Onchocerca volvulus 0.0506 0.4234 0.9591
Toxoplasma gondii proteasome subunit beta type, putative 0.0083 0.0613 0.1388
Toxoplasma gondii EGF family domain-containing protein 0.0017 0.0054 0.0123
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0361 0.0361
Schistosoma mansoni septate junction protein 0.0017 0.0054 0.0054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0506 0.4234 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0143 0.0325
Echinococcus multilocularis muscleblind protein 0.018 0.1449 0.1449
Trypanosoma cruzi conserved protein 0.0072 0.0517 0.0517
Trypanosoma brucei Calpain-like protein CALP1.3 0.0072 0.0517 0.1172
Brugia malayi Cathepsin L-like precursor 0.0506 0.4234 0.4234
Leishmania major cytochrome p450-like protein 0.0021 0.0083 0.0188
Brugia malayi beta-lactamase family protein 0.0036 0.0212 0.0212
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0083 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0933 0.2202
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0933 0.0933
Giardia lamblia Cathepsin B precursor 0.0448 0.3737 1
Echinococcus granulosus importin subunit beta 1 0.0028 0.0143 0.0143
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0164 0.0164
Echinococcus granulosus neurogenic locus notch protein 0.0017 0.0054 0.0054
Trypanosoma cruzi cysteine protease, putative 0.0277 0.2271 0.2271
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0378 0.0378
Echinococcus multilocularis lamin dm0 0.0026 0.0131 0.0131
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.008 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Loa Loa (eye worm) calpain D 0.0072 0.0517 0.0517
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0037 0.0037
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0055 0.0378 0.0893
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0044 0.0044
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0212 0.0212
Echinococcus multilocularis lamin 0.0026 0.0131 0.0131
Echinococcus granulosus prolyl endopeptidase 0.0527 0.4415 0.4415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.012 0.0933 0.2202
Schistosoma mansoni notch 0.0017 0.0054 0.0054
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0083 0.0031
Trypanosoma cruzi cysteine peptidase, putative 0.0506 0.4234 0.4234
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0231 0.0249
Trypanosoma cruzi caltractin, putative 0.0035 0.0205 0.0205
Schistosoma mansoni ran 0.0021 0.008 0.008
Mycobacterium ulcerans proteasome PrcB 0.0083 0.0613 0.0815
Toxoplasma gondii cathepsin CPC2 0.012 0.0933 0.2112
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0378 0.0378
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0348 0.0788
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Schistosoma mansoni ets-related 0.0011 0.0002 0.0002
Onchocerca volvulus 0.0236 0.1927 0.4366
Schistosoma mansoni hypothetical protein 0.0035 0.0205 0.0205
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0083 0.0613 0.1447
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0361 0.0361
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0083 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0933 0.2202
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0348 0.0348
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0816 0.1117
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0807 0.6813 1
Brugia malayi Papain family cysteine protease containing protein 0.0277 0.2271 0.2271
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0037 0.0037
Echinococcus multilocularis notch 0.0017 0.0054 0.0054
Echinococcus multilocularis fibropellin Ia 0.0017 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0205 0.0484
Onchocerca volvulus Cathepsin L homolog 0.0506 0.4234 0.9591
Plasmodium falciparum serine repeat antigen 2 0.012 0.0933 0.2202
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0933 0.0933
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0164 0.0164
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0448 0.3737 0.3737
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0127 0.0299
Echinococcus multilocularis programmed cell death protein 0.0039 0.0235 0.0235
Trypanosoma cruzi I/6 autoantigen, putative 0.0035 0.0205 0.0205
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0348 0.0348
Schistosoma mansoni reticulocalbin 0.0035 0.0205 0.0205
Echinococcus granulosus calpain 0.0257 0.2102 0.2102
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0348 0.0788
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0072 0.0517 0.0517
Giardia lamblia Hypothetical protein 0.012 0.0933 0.2495
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0083 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0933 0.2202
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0044 0.0044
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0055 0.0378 0.0856
Mycobacterium tuberculosis Hypothetical protein 0.0107 0.0816 0.1117
Trypanosoma cruzi calmodulin, putative 0.0035 0.0205 0.0205
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0613 0.0613
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.012 0.0933 0.2202
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.008 0.008
Schistosoma mansoni calmodulin related calcium binding protein 0.0035 0.0205 0.0205
Onchocerca volvulus 0.0028 0.0146 0.0331
Leishmania major i/6 autoantigen-like protein 0.0035 0.0205 0.0464
Schistosoma mansoni hypothetical protein 0.0017 0.0054 0.0054
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0011 0.0002 0.0002
Brugia malayi cathepsin F-like cysteine proteinase 0.012 0.0933 0.0933
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Schistosoma mansoni hypothetical protein 0.0011 0.0002 0.0002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0083 0.0031
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0083 0.0613 0.164
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0062 0.0142
Loa Loa (eye worm) hypothetical protein 0.0527 0.4415 0.4415
Trichomonas vaginalis centrin, putative 0.0035 0.0205 0.0484
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0062 0.0148
Giardia lamblia Hypothetical protein 0.012 0.0933 0.2495
Echinococcus multilocularis gamma secretase subunit aph 1 0.0734 0.619 0.619
Entamoeba histolytica Ran family GTPase 0.0021 0.008 0.019
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0288 0.2373 0.2373
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0212 0.0221
Plasmodium vivax importin-beta 2, putative 0.0028 0.0143 0.0338
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0506 0.4234 1
Plasmodium falciparum serine repeat antigen 3 0.012 0.0933 0.2202
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0729 0.6142 0.6142
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0083 0.0613 0.0815
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0933 0.0933
Entamoeba histolytica protein kinase, putative 0.0186 0.1493 0.3526
Giardia lamblia Cathepsin L precursor 0.012 0.0933 0.2495
Onchocerca volvulus 0.0047 0.0306 0.0692
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Schistosoma mansoni cytochrome P450 0.0021 0.0083 0.0083
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0348 0.0348
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0012 0.0004 0.0009
Loa Loa (eye worm) prolyl oligopeptidase 0.0055 0.0378 0.0378
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0348 0.0348
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0117 0.0264
Echinococcus granulosus acylamino acid releasing enzyme 0.0055 0.0378 0.0378
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0037 0.0037
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0033 0.0191 0.0191
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0306 0.0306
Echinococcus multilocularis musashi 0.0026 0.0131 0.0131
Plasmodium vivax vivapain-3 0.0277 0.2271 0.5364
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0164 0.0372
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0257 0.2102 0.2102
Echinococcus multilocularis GPCR, family 2 0.0015 0.0037 0.0037
Onchocerca volvulus 0.0506 0.4234 0.9591
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0072 0.0517 0.1222
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.012 0.0933 0.2202
Loa Loa (eye worm) calmodulin-like protein 0.0035 0.0205 0.0205
Trichomonas vaginalis calcineurin B subunit, putative 0.0035 0.0207 0.0489
Entamoeba histolytica prolyl oligopeptidase family protein 0.0055 0.0378 0.0893
Leishmania major calmodulin, putative 0.0035 0.0205 0.0464
Brugia malayi Fli-1 protein 0.0238 0.1946 0.1946
Loa Loa (eye worm) beta-lactamase 0.0036 0.0212 0.0212
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0083 0.0031
Echinococcus multilocularis cathepsin L 0.0277 0.2271 0.2271
Onchocerca volvulus Chorion peroxidase homolog 0.0213 0.1724 0.3906
Leishmania major GTP-binding protein, putative 0.0021 0.008 0.0182
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0072 0.0517 0.0517
Trypanosoma brucei calpain-like protein, putative 0.0257 0.2102 0.476
Loa Loa (eye worm) animal heme peroxidase 0.0213 0.1724 0.1724
Entamoeba histolytica cysteine proteinase, putative 0.0277 0.2271 0.5364
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Echinococcus granulosus calcium uptake protein 1 0.0035 0.0207 0.0207
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0212 0.05
Schistosoma mansoni neuronal calcium sensor 0.0035 0.0205 0.0205
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0072 0.0517 0.1172
Entamoeba histolytica prolyl oligopeptidase family protein 0.0055 0.0378 0.0893
Trypanosoma cruzi kinesin, putative 0.0185 0.1489 0.1489
Trypanosoma cruzi centrin, putative 0.0039 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.07 0.07
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0349 0.2896 0.2896
Trichomonas vaginalis calmodulin, putative 0.0035 0.0205 0.0484
Entamoeba histolytica cysteine protease, putative 0.0277 0.2271 0.5364
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0035 0.0205 0.0205
Schistosoma mansoni intermediate filament proteins 0.0026 0.0131 0.0131
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0083 0.0031
Echinococcus granulosus programmed cell death protein 0.0039 0.0235 0.0235
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0527 0.4415 0.4415
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0933 0.2202
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0035 0.0205 0.0484
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0002 0.0002
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0729 0.6142 0.6142
Onchocerca volvulus 0.0506 0.4234 0.9591
Brugia malayi Ets-domain containing protein 0.0011 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.0077 0.0562 0.0562
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.476
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0083 0.0613 0.1388
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0231 0.0231
Schistosoma mansoni hypothetical protein 0.0297 0.245 0.245
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0127 0.0287
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0098 0.0232
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.012 0.0933 0.2202
Echinococcus multilocularis calpain family protein 1, d 0.0509 0.4257 0.4257
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0035 0.0205 0.0484
Giardia lamblia Cysteine protease 0.012 0.0933 0.2495
Brugia malayi calpain D 0.0072 0.0517 0.0517
Schistosoma mansoni notch 0.0017 0.0054 0.0054
Trichomonas vaginalis calcineurin B subunit, putative 0.0035 0.0205 0.0484
Echinococcus granulosus fibropellin Ia 0.0017 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Trichomonas vaginalis calcium binding proteins, putative 0.0035 0.0205 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.012 0.0933 0.2202
Loa Loa (eye worm) hypothetical protein 0.0036 0.0212 0.0212
Brugia malayi cathepsin L-like precursor 0.0349 0.2896 0.2896
Mycobacterium tuberculosis Conserved protein 0.0036 0.0212 0.0221
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0306 0.0306
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0055 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0437 0.3645 0.3645
Loa Loa (eye worm) hypothetical protein 0.0017 0.0054 0.0054
Entamoeba histolytica hypothetical protein, conserved 0.0055 0.0378 0.0893
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0212 0.05
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0083 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0933 0.2202
Brugia malayi mbt repeat family protein 0.0047 0.0306 0.0306
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0348 0.0348
Echinococcus granulosus lamin dm0 0.0026 0.0131 0.0131
Echinococcus multilocularis calumenin 0.0035 0.0207 0.0207
Echinococcus granulosus calpain A 0.0729 0.6144 0.6144
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2102 0.476
Plasmodium vivax proteasome subunit beta type-5, putative 0.0083 0.0613 0.1447
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.4234 1
Giardia lamblia Cathepsin B precursor 0.0448 0.3737 1
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0055 0.0378 0.0378
Leishmania major cathepsin L-like protease 0.0506 0.4234 0.9591
Schistosoma mansoni flap endonuclease-1 0.0023 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0509 0.4257 0.4257
Leishmania major hypothetical protein, conserved 0.0025 0.0117 0.0264
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0083 0.0083
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0231 0.0231
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0306 0.0306
Schistosoma mansoni laminin gamma-3 chain 0.0017 0.0054 0.0054
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0072 0.0517 0.1222
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0277 0.2271 0.2271
Echinococcus granulosus Dipeptidyl peptidase 9 0.0055 0.0378 0.0378
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0055 0.0378 0.0893

Activities

Activity type Activity value Assay description Source Reference
Potency (binding) 14.1254 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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