Detailed information for compound 1480642

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 241.247 | Formula: C9H15N5O3
  • H donors: 6 H acceptors: 5 LogP: -0.89 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 2
  • SMILES: C[C@@H]([C@@H](C1CNc2c(N1)nc(nc2O)N)O)O
  • InChi: 1S/C9H15N5O3/c1-3(15)6(16)4-2-11-5-7(12-4)13-9(10)14-8(5)17/h3-4,6,11,15-16H,2H2,1H3,(H4,10,12,13,14,17)/t3-,4?,6-/m0/s1
  • InChiKey: UUJCZDAMSPXYEU-BYAPIUGTSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0151 0.0036 0.0167
Trichomonas vaginalis calmodulin, putative 0.0151 0.0036 0.012
Entamoeba histolytica grainin 2 0.0183 0.0143 0.0669
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1224 0.369 0.369
Brugia malayi calpain 7 0.1079 0.3194 0.3194
Echinococcus multilocularis calpain 5 0.1079 0.3194 0.3194
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Loa Loa (eye worm) programmed cell death protein 6 0.0152 0.0037 0.0037
Trypanosoma brucei calmodulin, putative 0.0151 0.0036 0.0112
Echinococcus granulosus cathepsin b 0.3077 1 1
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0151 0.0036 0.0036
Trichomonas vaginalis calpain, putative 0.0313 0.0585 0.1965
Trichomonas vaginalis calcineurin B subunit, putative 0.0152 0.0037 0.0125
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trichomonas vaginalis centrin, putative 0.0151 0.0036 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 0.3194
Giardia lamblia Cathepsin B precursor 0.1015 0.2978 1
Plasmodium falciparum centrin-1 0.0151 0.0036 0.026
Trichomonas vaginalis calcineurin B subunit, putative 0.0151 0.0036 0.012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0313 0.0585 0.0585
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0766 0.2128 0.2128
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0313 0.0585 0.0585
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0036 0.0036
Trypanosoma brucei calpain, putative 0.0313 0.0585 0.1832
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Echinococcus multilocularis calmodulin 0.0151 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0151 0.0036 0.0036
Trichomonas vaginalis calmodulin, putative 0.0151 0.0036 0.012
Leishmania major i/6 autoantigen-like protein 0.0151 0.0036 0.0112
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0313 0.0585 0.1965
Leishmania major calmodulin, putative 0.0151 0.0036 0.0112
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0151 0.0036 0.0112
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0313 0.0585 0.1832
Loa Loa (eye worm) prolyl oligopeptidase 0.0766 0.2128 0.2128
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Loa Loa (eye worm) calpain D 0.0313 0.0585 0.0585
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0313 0.0585 0.0585
Echinococcus granulosus calcium uptake protein 1 0.0152 0.0037 0.0037
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0257 0.0397 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0313 0.0585 0.1965
Trypanosoma cruzi caltractin, putative 0.0151 0.0036 0.0036
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0544 0.1371 0.4604
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0766 0.2128 0.3746
Echinococcus granulosus neurocalcin 0.0151 0.0036 0.0036
Echinococcus multilocularis cathepsin b 0.3077 1 1
Plasmodium vivax hypothetical protein, conserved 0.0152 0.0037 0.0117
Plasmodium falciparum calpain 0.0313 0.0585 0.4267
Trypanosoma cruzi I/6 autoantigen, putative 0.0151 0.0036 0.0036
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.3039 0.987 0.987
Echinococcus multilocularis calcium uptake protein 1 0.0152 0.0037 0.0037
Trypanosoma cruzi calmodulin, putative 0.0151 0.0036 0.0036
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0403 0.0891 0.2993
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Echinococcus multilocularis calpain 7 (C02 family) 0.1079 0.3194 0.3194
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0036 0.0036
Echinococcus granulosus calpain A 0.1079 0.3194 0.3194
Leishmania major programmed cell death 6 protein-like protein 0.0151 0.0036 0.0112
Trypanosoma brucei calpain-like protein, putative 0.1079 0.3194 1
Trypanosoma brucei cysteine peptidase, putative 0.0313 0.0585 0.1832
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 1
Loa Loa (eye worm) calmodulin-like protein 0.0151 0.0036 0.0036
Trichomonas vaginalis calcium binding protein, putative 0.0151 0.0036 0.012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 0.3194
Toxoplasma gondii hypothetical protein 0.0403 0.0891 0.2993
Echinococcus multilocularis calbindin 32 0.0152 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0313 0.0585 0.1965
Echinococcus granulosus EF HAND 1 calcium binding site 0.0151 0.0036 0.0036
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0544 0.1371 0.4604
Brugia malayi calpain family protein 1 0.2887 0.9354 0.9354
Brugia malayi calpain 5 0.0766 0.2129 0.2129
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Loa Loa (eye worm) hypothetical protein 0.0151 0.0036 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1015 0.2978 0.2978
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trypanosoma brucei calmodulin, putative 0.0152 0.0037 0.0117
Giardia lamblia Rab geranylgeranyltransferase 0.0544 0.1371 0.4604
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1015 0.2978 0.2978
Echinococcus multilocularis programmed cell death protein 0.0183 0.0143 0.0143
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0257 0.0397 0.1242
Echinococcus granulosus calpain A 0.3039 0.9871 0.9871
Trichomonas vaginalis calcium binding protein, putative 0.0183 0.0143 0.0479
Trypanosoma brucei Calpain-like protein 1.2 0.0313 0.0585 0.1832
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3077 1 1
Giardia lamblia Hypothetical protein 0.0152 0.0037 0.0125
Brugia malayi hypothetical protein 0.0197 0.019 0.019
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3077 1 1
Schistosoma mansoni calmodulin 0.0151 0.0036 0.0036
Entamoeba histolytica calmodulin, putative 0.0151 0.0036 0.0167
Echinococcus granulosus calpain 7 C02 family 0.1079 0.3194 0.3194
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0151 0.0036 0.0112
Echinococcus multilocularis EF hand domain containing family member A2 0.0151 0.0036 0.0036
Schistosoma mansoni centrin 0.0151 0.0036 0.0036
Echinococcus granulosus cathepsin b 0.3077 1 1
Trypanosoma cruzi centrin, putative 0.0183 0.0143 0.0143
Brugia malayi Calmodulin-like protein 0.0151 0.0036 0.0036
Schistosoma mansoni centrin-related 0.0151 0.0036 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 1
Leishmania major hypothetical protein, conserved 0.0313 0.0585 0.1832
Schistosoma mansoni calmodulin 0.0151 0.0036 0.0036
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0151 0.0036 0.0036
Schistosoma mansoni calmodulin related calcium binding protein 0.0151 0.0036 0.0036
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 0.3194
Trichomonas vaginalis calmodulin, putative 0.0151 0.0036 0.012
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1079 0.3194 0.3194
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3039 0.987 0.987
Schistosoma mansoni calpain (C02 family) 0.1079 0.3194 0.3194
Trypanosoma brucei protein I/6 0.0151 0.0036 0.0112
Toxoplasma gondii troponin c, isotype gamma, putative 0.0151 0.0036 0.012
Schistosoma mansoni calpain C (C02 family) 0.1079 0.3194 0.3194
Leishmania major calmodulin-like protein 0.0151 0.0036 0.0112
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0544 0.1371 0.6441
Trichomonas vaginalis centrin, putative 0.0151 0.0036 0.012
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0544 0.1371 0.1371
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3077 1 1
Trichomonas vaginalis myosin light chain 1, putative 0.0151 0.0036 0.012
Echinococcus multilocularis neuronal calcium sensor 0.0151 0.0036 0.0036
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0544 0.1371 0.4604
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1079 0.3194 0.3194
Brugia malayi calpain family protein 1 0.2887 0.9354 0.9354
Brugia malayi programmed cell death protein 6 0.0151 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.2575 0.8289 0.8289
Toxoplasma gondii centrin 0.0151 0.0036 0.012
Onchocerca volvulus 0.0151 0.0036 0.0063
Onchocerca volvulus 0.1809 0.568 1
Schistosoma mansoni calpain-7 (C02 family) 0.1079 0.3194 0.3194
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Toxoplasma gondii EFHC1, putative 0.0151 0.0036 0.012
Toxoplasma gondii calmodulin CAM1 0.0152 0.0037 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0036 0.012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1079 0.3194 0.3194
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0151 0.0036 0.012
Brugia malayi EF hand family protein 0.0152 0.0037 0.0037
Trichomonas vaginalis calmodulin, putative 0.0152 0.0037 0.0125
Trypanosoma cruzi centrin-3 0.0183 0.0143 0.0143
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0313 0.0585 0.0585
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0151 0.0036 0.012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0313 0.0585 0.0585
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0036 0.0036
Trichomonas vaginalis hypothetical protein 0.0313 0.0585 0.1965
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3039 0.987 0.987
Trypanosoma brucei Component of motile flagella 41 0.0151 0.0036 0.0112
Echinococcus granulosus Dipeptidyl peptidase 9 0.0257 0.0397 0.0397
Echinococcus multilocularis programmed cell death protein 0.0183 0.0143 0.0143
Leishmania major calmodulin-like protein 0.0151 0.0036 0.0112
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0257 0.0397 0.0397
Trypanosoma cruzi kinesin, putative 0.0766 0.2129 0.2129
Giardia lamblia Cathepsin B precursor 0.1015 0.2978 1
Leishmania major centrin, putative 0.0151 0.0036 0.0112
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0151 0.0036 0.0036
Trypanosoma brucei centrin, putative 0.0151 0.0036 0.0112
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0151 0.0036 0.0036
Loa Loa (eye worm) calpain 5 0.0766 0.2129 0.2129
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0313 0.0585 0.1832
Loa Loa (eye worm) EF hand family protein 0.0151 0.0036 0.0036
Trichomonas vaginalis calmodulin, putative 0.0151 0.0036 0.012
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0313 0.0585 0.1965
Leishmania major hypothetical protein, conserved 0.0152 0.0037 0.0117
Echinococcus multilocularis cathepsin b 0.3077 1 1
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0856 0.2434 0.2434
Echinococcus multilocularis neurocalcin 0.0151 0.0036 0.0036
Schistosoma mansoni reticulocalbin 0.0151 0.0036 0.0036
Entamoeba histolytica grainin, putative 0.0152 0.0037 0.0175
Brugia malayi calpain D 0.0313 0.0585 0.0585
Trypanosoma brucei Calpain-like protein 1.1 0.0313 0.0585 0.1832
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0152 0.0037 0.0037
Trypanosoma brucei mitochondrial calcium uptake 1 0.0151 0.0036 0.0112
Entamoeba histolytica calpain family cysteine protease, putative 0.0313 0.0585 0.2748
Brugia malayi calpain 5 0.0313 0.0585 0.0585
Schistosoma mansoni hypothetical protein 0.0151 0.0036 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 1
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0544 0.1371 0.1371
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trypanosoma brucei calpain-like protein, putative 0.1079 0.3194 1
Loa Loa (eye worm) cathepsin B 0.1015 0.2978 0.2978
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0544 0.1371 0.1371
Leishmania major protein kinase, putative 0.0151 0.0036 0.0112
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0544 0.1371 0.4293
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1079 0.3194 0.3194
Trypanosoma cruzi calmodulin, putative 0.0151 0.0036 0.0036
Schistosoma mansoni calpain-2 (C02 family) 0.0313 0.0585 0.0585
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0313 0.0585 0.1832
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0036 0.012
Loa Loa (eye worm) hypothetical protein 0.0313 0.0585 0.0585
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0766 0.2128 0.2128
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trichomonas vaginalis calcium binding protein, putative 0.0151 0.0036 0.012
Trypanosoma brucei cysteine peptidase C (CPC) 0.1015 0.2978 0.9324
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0856 0.2434 0.2434
Trichomonas vaginalis calmodulin, putative 0.0151 0.0036 0.012
Echinococcus multilocularis calumenin 0.0152 0.0037 0.0037
Toxoplasma gondii calcium-dependent protein kinase 0.0152 0.0037 0.0125
Trypanosoma cruzi conserved protein 0.0313 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.2887 0.9354 0.9354
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1015 0.2978 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0313 0.0585 0.1965
Toxoplasma gondii aromatic amino acid hydrolase AAH1 0.023 0.0302 0.1013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0313 0.0585 0.0585
Schistosoma mansoni mitochondrial solute carrier 0.0151 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0313 0.0585 0.1965
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0257 0.0397 0.0397
Entamoeba histolytica protein kinase, putative 0.0766 0.2129 1
Plasmodium vivax calpain, putative 0.1079 0.3194 1
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0313 0.0585 0.1965
Leishmania major phospholipase c-like protein 0.0151 0.0036 0.0112
Entamoeba histolytica calcium-binding protein, putative 0.0151 0.0036 0.0167
Loa Loa (eye worm) calpain 0.1079 0.3194 0.3194
Echinococcus multilocularis calmodulin 0.0151 0.0036 0.0036
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1015 0.2978 0.9324
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3077 1 1
Brugia malayi EF hand family protein 0.0151 0.0036 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0151 0.0036 0.0112
Entamoeba histolytica hypothetical protein, conserved 0.0152 0.0037 0.0175
Echinococcus granulosus calumenin 0.0152 0.0037 0.0037
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0257 0.0397 0.1242
Trichomonas vaginalis calcium binding proteins, putative 0.0151 0.0036 0.012
Toxoplasma gondii phenylalanine-4-hydroxylase 0.0253 0.0383 0.1286
Plasmodium vivax centrin-1, putative 0.0151 0.0036 0.0112
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0313 0.0585 0.0585
Echinococcus granulosus EF hand domain containing family member A2 0.0152 0.0037 0.0037
Echinococcus multilocularis calpain 0.1079 0.3194 0.3194
Leishmania major centrin, putative 0.0151 0.0036 0.0112
Echinococcus granulosus calpain 5 0.1079 0.3194 0.3194
Loa Loa (eye worm) hypothetical protein 0.2121 0.6745 0.6745
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0257 0.0397 0.1332
Loa Loa (eye worm) calpain family protein 1 0.2121 0.6745 0.6745
Toxoplasma gondii hypothetical protein 0.0313 0.0585 0.1965
Leishmania major calmodulin, putative 0.0151 0.0036 0.0112
Schistosoma mansoni reticulocalbin 0.0152 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0544 0.1371 0.1371
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0151 0.0036 0.0036
Toxoplasma gondii centrin, putative 0.0151 0.0036 0.012
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0151 0.0036 0.0036
Toxoplasma gondii cathepsin B 0.1015 0.2978 1
Schistosoma mansoni rab 0.0151 0.0036 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trypanosoma cruzi kinesin, putative 0.0766 0.2129 0.2129
Trichomonas vaginalis calmodulin, putative 0.0151 0.0036 0.012
Echinococcus multilocularis centrin 2 0.0151 0.0036 0.0036
Leishmania major centrin, putative,caltractin, putative 0.0151 0.0036 0.0112
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3077 1 1
Onchocerca volvulus 0.0151 0.0036 0.0063
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Trypanosoma brucei kinesin, putative 0.0766 0.2129 0.6666
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0313 0.0585 0.1965
Echinococcus multilocularis EF hand domain containing family member A2 0.0152 0.0037 0.0037
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0151 0.0036 0.0036
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0151 0.0036 0.0036
Trypanosoma cruzi calmodulin, putative 0.0151 0.0036 0.0036
Echinococcus granulosus centrin 2 0.0151 0.0036 0.0036
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0544 0.1371 0.1371
Echinococcus multilocularis hypothetical protein 0.1079 0.3194 0.3194
Trypanosoma brucei I/6 autoantigen 0.0151 0.0036 0.0112
Echinococcus granulosus calmodulin 0.0151 0.0036 0.0036
Schistosoma mansoni ef hand domain family member A2 0.0151 0.0036 0.0036
Brugia malayi prolyl oligopeptidase family protein 0.0766 0.2128 0.2128
Schistosoma mansoni hypothetical protein 0.0151 0.0036 0.0036
Trypanosoma cruzi I/6 autoantigen, putative 0.0151 0.0036 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0151 0.0036 0.0112
Trichomonas vaginalis calcium binding protein, putative 0.0151 0.0036 0.012
Echinococcus granulosus neuronal calcium sensor 0.0151 0.0036 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0223 0.0278 0.0278
Schistosoma mansoni hypothetical protein 0.0313 0.0585 0.0585
Leishmania major hypothetical protein, unknown function 0.0313 0.0585 0.1832
Trypanosoma brucei antigen, putative 0.1079 0.3194 1
Leishmania major calpain protease-like protein 0.0313 0.0585 0.1832
Brugia malayi prolyl oligopeptidase family protein 0.0257 0.0397 0.0397
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0766 0.2128 0.2128
Trichomonas vaginalis calmodulin, putative 0.0183 0.0143 0.0479
Trichomonas vaginalis calpain, putative 0.0313 0.0585 0.1965
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1079 0.3194 1
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0257 0.0397 0.0397
Trypanosoma brucei centrin, putative 0.0151 0.0036 0.0112
Schistosoma mansoni Mername-AA248 (C02 family) 0.1079 0.3194 0.3194
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0313 0.0585 0.0585
Trypanosoma brucei hypothetical protein 0.0313 0.0585 0.1832
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0313 0.0585 0.0585
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1079 0.3194 0.3194
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1079 0.3194 0.3194
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0036 0.0036
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2887 0.9354 0.9354
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0152 0.0037 0.0037
Loa Loa (eye worm) calpain family protein 1 0.2887 0.9354 0.9354
Toxoplasma gondii EF hand domain-containing protein 0.0151 0.0036 0.012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0313 0.0585 0.0585
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0544 0.1371 0.1371
Leishmania major phenylalanine-4-hydroxylase,phenylalanine-4-hydroxylase, putative 0.023 0.0302 0.0945
Loa Loa (eye worm) hypothetical protein 0.0197 0.019 0.019
Leishmania major hypothetical protein, conserved 0.0151 0.0036 0.0112
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0257 0.0397 0.1242
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0856 0.2434 0.2434
Trypanosoma brucei caltractin, putative 0.0183 0.0143 0.0446
Trypanosoma brucei centrin-3 0.0183 0.0143 0.0446
Echinococcus multilocularis calpain A 0.3039 0.9871 0.9871
Onchocerca volvulus 0.0152 0.0037 0.0066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.0585
Echinococcus multilocularis calpain family protein 1, d 0.2121 0.6745 0.6745
Trichomonas vaginalis calmodulin, putative 0.0151 0.0036 0.012
Echinococcus granulosus programmed cell death protein 0.0183 0.0143 0.0143
Trypanosoma brucei Calpain-like protein 2 0.0313 0.0585 0.1832
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.3039 0.987 0.987
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0544 0.1371 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1079 0.3194 0.3194
Trypanosoma brucei calpain, putative 0.0313 0.0585 0.1832
Entamoeba histolytica calcium binding family protein 0.0151 0.0036 0.0167
Trypanosoma brucei calpain-like protein, putative 0.1079 0.3194 1
Trypanosoma cruzi centrin, putative 0.0183 0.0143 0.0143
Leishmania major kinesin, putative 0.0766 0.2129 0.6666
Toxoplasma gondii aromatic amino acid hydrolase AAH2 0.0253 0.0383 0.1286
Loa Loa (eye worm) hypothetical protein 0.3077 1 1
Loa Loa (eye worm) hypothetical protein 0.1809 0.568 0.568
Trypanosoma brucei Calpain-like protein CALP1.3 0.0313 0.0585 0.1832
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0151 0.0036 0.0167
Leishmania major calcineurin B subunit, putative 0.0151 0.0036 0.0112
Echinococcus granulosus EF hand domain containing family member A2 0.0151 0.0036 0.0036
Trichomonas vaginalis calpain, putative 0.0313 0.0585 0.1965
Trichomonas vaginalis calmodulin-2, putative 0.0151 0.0036 0.012
Giardia lamblia Cathepsin B precursor 0.1015 0.2978 1
Echinococcus granulosus calpain 0.1079 0.3194 0.3194
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0151 0.0036 0.0036
Brugia malayi calcium-binding protein 0.0151 0.0036 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0313 0.0585 0.1832
Trypanosoma brucei calpain-like protein, putative 0.1079 0.3194 1
Echinococcus granulosus calbindin 32 0.0152 0.0037 0.0037
Leishmania major calpain family cysteine protease-like protein 0.0313 0.0585 0.1832
Schistosoma mansoni calpain-7 (C02 family) 0.1079 0.3194 0.3194
Entamoeba histolytica calpain large subunit domain III containing protein 0.0766 0.2129 1
Entamoeba histolytica calmodulin, putative 0.0151 0.0036 0.0167

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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