Detailed information for compound 1657519

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 236.307 | Formula: C14H20O3
  • H donors: 0 H acceptors: 2 LogP: 2.33 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC/C=C\C[C@@H]1[C@@H](C=CC1=O)CC(=O)OCC
  • InChi: 1S/C14H20O3/c1-3-5-6-7-12-11(8-9-13(12)15)10-14(16)17-4-2/h5-6,8-9,11-12H,3-4,7,10H2,1-2H3/b6-5-/t11-,12+/m0/s1
  • InChiKey: WLFXPBFZFCOQOH-ABZJQCSKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0032 0.0033
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0057 0.0256 0.0746
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0137 0.04
Echinococcus granulosus Pleckstrin G protein interacting region 0.0019 0.0032 0.0033
Leishmania major calmodulin-like protein 0.0069 0.0326 0.0951
Treponema pallidum heat shock protein 90 0.0028 0.0083 0.5
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0126 0.0126
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.2331
Loa Loa (eye worm) hypothetical protein 0.0069 0.0326 0.0333
Echinococcus multilocularis geminin 0.0899 0.5213 0.5213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0115 0.0598 0.0611
Giardia lamblia Cathepsin L precursor 0.0109 0.0561 0.1435
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0174 0.0178
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0124 0.036
Toxoplasma gondii EFHC1, putative 0.0069 0.0326 0.0943
Echinococcus multilocularis calpain 0.0401 0.2284 0.2284
Echinococcus multilocularis calumenin 0.007 0.0335 0.0334
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Schistosoma mansoni cpg binding protein 0.0031 0.0101 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0109 0.0561 0.1642
Brugia malayi Papain family cysteine protease containing protein 0.0109 0.0561 0.0573
Echinococcus multilocularis tar DNA binding protein 0.0134 0.0708 0.0708
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0108 0.0556 0.0568
Schistosoma mansoni calpain (C02 family) 0.0401 0.2284 0.2331
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0109 0.0561 0.0573
Schistosoma mansoni hypothetical protein 0.0067 0.0316 0.0322
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0126 0.0356
Loa Loa (eye worm) hypothetical protein 0.0038 0.0144 0.0147
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0144 0.0613
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0055 0.0056
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0375 0.2129 0.2128
Loa Loa (eye worm) programmed cell death protein 6 0.007 0.0335 0.0341
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0137 0.04
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0375 0.2129 1
Schistosoma mansoni endoplasmin 0.0035 0.0124 0.0127
Plasmodium vivax hypothetical protein, conserved 0.007 0.0335 0.1449
Entamoeba histolytica peptidase, C54 family 0.0049 0.0207 0.0971
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0174 0.0178
Toxoplasma gondii centrin 0.0069 0.0326 0.0943
Echinococcus granulosus X box binding protein 1 0.0303 0.1705 0.174
Plasmodium vivax vivapain-1 0.0217 0.1197 0.5231
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0326 0.0954
Schistosoma mansoni calmodulin 0.0069 0.0326 0.0333
Brugia malayi calpain 5 0.0286 0.1607 0.164
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0.0124 0.0127
Brugia malayi fibroinase precursor 0.0109 0.0561 0.0573
Echinococcus granulosus lamin dm0 0.0086 0.0427 0.0436
Trichomonas vaginalis calpain, putative 0.0115 0.0598 0.175
Schistosoma mansoni smad1 5 8 and 0.0017 0.0023 0.0023
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0174 0.0178
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0069 0.0326 0.0333
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.0561 0.0573
Brugia malayi heat shock protein 90 0.0035 0.0124 0.0127
Giardia lamblia Cysteine protease 0.0109 0.0561 0.1435
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0109 0.0561 0.0573
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1678 0.9797 1
Onchocerca volvulus 0.0375 0.2129 0.2619
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0033
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.004 0.0041
Schistosoma mansoni neuronal calcium sensor 0.0069 0.0326 0.0333
Entamoeba histolytica cysteine protease, putative 0.0375 0.2129 1
Mycobacterium tuberculosis Conserved protein 0.0038 0.0144 0.0484
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0174 0.0174
Toxoplasma gondii cathepsin CPL 0.0375 0.2129 0.6223
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0115 0.0598 0.1747
Loa Loa (eye worm) hypothetical protein 0.0108 0.0556 0.0568
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Toxoplasma gondii ABC1 family protein 0.0038 0.0144 0.0409
Echinococcus granulosus Peptidase C54 0.0124 0.0654 0.0667
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0401 0.2284 0.6682
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0144 0.2805
Schistosoma mansoni nuclear hormone receptor 0.002 0.004 0.0041
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0556 0.0568
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0169 0.0918 0.0937
Echinococcus granulosus Smad4 0.0017 0.0023 0.0023
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.004 0.0041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.2331
Trypanosoma brucei kinesin, putative 0.0286 0.1607 0.4699
Giardia lamblia Hypothetical protein 0.007 0.0335 0.0755
Echinococcus multilocularis endoplasmin 0.0028 0.0083 0.0083
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.004 0.0041
Entamoeba histolytica cysteine protease, putative 0.0109 0.0561 0.2637
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Onchocerca volvulus Phospholipase A2 homolog 0.0294 0.1649 0.2028
Echinococcus multilocularis cathepsin L cysteine protease 0.0375 0.2129 0.2128
Echinococcus granulosus centrin 2 0.0069 0.0326 0.0333
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0401 0.2284 0.2331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0561 0.1642
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0032 0.0033
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0019 0.0032 0.0033
Entamoeba histolytica calmodulin, putative 0.0069 0.0326 0.1533
Schistosoma mansoni hypothetical protein 0.0067 0.0316 0.0322
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0101 0.0103
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0137 0.0388
Echinococcus multilocularis centrin 2 0.0069 0.0326 0.0326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Loa Loa (eye worm) calpain 5 0.0286 0.1607 0.164
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1146 0.6668 0.6807
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0023 0.0022
Brugia malayi hypothetical protein 0.0023 0.0055 0.0056
Onchocerca volvulus 0.0375 0.2129 0.2619
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0108 0.0556 0.0568
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0219 0.0219
Brugia malayi calpain 5 0.0115 0.0598 0.0611
Schistosoma mansoni smad 0.0017 0.0023 0.0023
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0099
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0046 0.0134
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0115 0.0598 0.0611
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0192 0.0196
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0375 0.2129 0.2128
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0594 0.3418 0.3489
Schistosoma mansoni hypothetical protein 0.0115 0.0598 0.0611
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0067 0.0316 0.0316
Schistosoma mansoni cathepsin F (C01 family) 0.0375 0.2129 0.2173
Brugia malayi DIX domain containing protein 0.0019 0.0032 0.0033
Brugia malayi calcium-binding protein 0.0069 0.0326 0.0333
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0028 0.0083 0.0085
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0375 0.2129 1
Schistosoma mansoni nuclear receptor 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0038 0.0144 0.0147
Giardia lamblia Cathepsin L precursor 0.0109 0.0561 0.1435
Trypanosoma cruzi heat shock protein 85, putative 0.0028 0.0083 0.0085
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0137 0.04
Loa Loa (eye worm) hypothetical protein 0.0038 0.0144 0.0147
Plasmodium falciparum phd finger protein, putative 0.0031 0.0101 0.0458
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0004
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0124 0.0127
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0219 0.0628
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0109 0.0561 0.0573
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Echinococcus multilocularis musashi 0.0086 0.0427 0.0427
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0219 0.0219
Echinococcus multilocularis calmodulin 0.0069 0.0326 0.0326
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0109 0.0561 0.0573
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Brugia malayi Peptidase C13 family protein 0.015 0.0803 0.082
Trypanosoma brucei Heat shock protein 83, putative 0.0035 0.0124 0.036
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0115 0.0598 0.174
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0174 0.0178
Echinococcus multilocularis neuropeptide receptor A26 0.0493 0.2823 0.2823
Brugia malayi Papain family cysteine protease containing protein 0.0109 0.0561 0.0573
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0174 0.0214
Echinococcus granulosus geminin 0.0899 0.5213 0.5322
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.6682
Brugia malayi Cathepsin L-like precursor 0.0375 0.2129 0.2173
Brugia malayi MH1 domain containing protein 0.0017 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0109 0.0561 0.1642
Loa Loa (eye worm) hypothetical protein 0.0262 0.1463 0.1493
Trichomonas vaginalis calcineurin B subunit, putative 0.0069 0.0326 0.0954
Giardia lamblia Cathepsin B precursor 0.0109 0.0561 0.1435
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0023 0.0023
Echinococcus multilocularis cathepsin b 0.1678 0.9797 0.9797
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0144 0.0484
Trypanosoma brucei cysteine peptidase C (CPC) 0.0594 0.3418 1
Trypanosoma brucei Calpain-like protein 1.2 0.0115 0.0598 0.1747
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0174 0.0214
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0055 0.0055
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.004 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0174 0.0178
Trypanosoma brucei calpain-like protein, putative 0.0401 0.2284 0.6682
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0109 0.0561 0.2622
Onchocerca volvulus 0.0086 0.0427 0.0526
Echinococcus granulosus heat shock protein 90 0.0028 0.0083 0.0085
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0174 0.0178
Loa Loa (eye worm) hypothetical protein 0.0108 0.0556 0.0568
Leishmania major calcineurin B subunit, putative 0.0069 0.0326 0.0951
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0708 0.0723
Trichomonas vaginalis centrin, putative 0.0069 0.0326 0.0954
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0301 0.0307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Giardia lamblia Cathepsin L precursor 0.0109 0.0561 0.1435
Brugia malayi MH2 domain containing protein 0.0017 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0303 0.1705 0.174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0172 0.0172
Trichomonas vaginalis centrin, putative 0.0069 0.0326 0.0954
Loa Loa (eye worm) hypothetical protein 0.0044 0.0177 0.0181
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0144 0.0484
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0137 0.0396
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0109 0.0561 0.0573
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Loa Loa (eye worm) hypothetical protein 0.0067 0.0316 0.0322
Echinococcus granulosus EF HAND 1 calcium binding site 0.0069 0.0326 0.0333
Toxoplasma gondii centrin, putative 0.0069 0.0326 0.0943
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.015 0.0153
Loa Loa (eye worm) hypothetical protein 0.1394 0.8128 0.8297
Onchocerca volvulus Huntingtin homolog 0.0262 0.1463 0.18
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0109 0.0561 0.1435
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0137 0.014
Plasmodium vivax heat shock protein 86, putative 0.0035 0.0124 0.0526
Trichomonas vaginalis calmodulin, putative 0.0069 0.0326 0.0954
Echinococcus granulosus EF hand domain containing family member A2 0.0069 0.0326 0.0333
Trichomonas vaginalis calmodulin, putative 0.007 0.0335 0.0979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.2331
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Onchocerca volvulus 0.0676 0.39 0.4798
Leishmania major phospholipase c-like protein 0.0069 0.0326 0.0951
Leishmania major calmodulin, putative 0.0069 0.0326 0.0951
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0083 0.0242
Trichomonas vaginalis calcium binding protein, putative 0.0072 0.0347 0.1015
Echinococcus multilocularis cysteine protease 0.0375 0.2129 0.2128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus multilocularis neurocalcin 0.0069 0.0326 0.0326
Plasmodium falciparum serine repeat antigen 1 0.0109 0.0561 0.2622
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0301 1
Echinococcus granulosus neuronal calcium sensor 0.0069 0.0326 0.0333
Trypanosoma brucei Component of motile flagella 41 0.0069 0.0326 0.0951
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Brugia malayi Nuclear hormone receptor E75 0.002 0.004 0.0041
Leishmania major centrin, putative,caltractin, putative 0.0069 0.0326 0.0951
Brugia malayi cathepsin F-like cysteine proteinase 0.0108 0.0556 0.0568
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0126 0.0368
Onchocerca volvulus 0.0019 0.0032 0.0039
Giardia lamblia Encystation-specific protease 0.0109 0.0561 0.1435
Echinococcus granulosus peregrin 0.0031 0.0101 0.0104
Brugia malayi Cathepsin L-like precursor 0.0267 0.1493 0.1524
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Schistosoma mansoni smad1 5 8 and 0.0017 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.1678 0.9797 1
Brugia malayi hypothetical protein 0.003 0.0097 0.0099
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0115 0.0598 0.175
Loa Loa (eye worm) calpain family protein 1 0.0791 0.4578 0.4673
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0069 0.0326 0.0333
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0000066172 0.0000067546
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0032 0.0033
Loa Loa (eye worm) cysteine protease 0.0375 0.2129 0.2173
Trypanosoma brucei Calpain-like protein 2 0.0115 0.0598 0.1747
Plasmodium falciparum serine repeat antigen 8 0.0109 0.0561 0.2622
Echinococcus multilocularis cathepsin b 0.1678 0.9797 0.9797
Trichomonas vaginalis esterase, putative 0.0038 0.0144 0.0421
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0594 0.3418 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.6682
Schistosoma mansoni cathepsin C 0.0109 0.0561 0.0573
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0019 0.0032 0.0033
Trypanosoma cruzi hypothetical protein 0.0013 0.0000066172 0.0000067546
Echinococcus granulosus calumenin 0.007 0.0335 0.0341
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0126 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0174 0.0178
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Giardia lamblia Cathepsin L precursor 0.0109 0.0561 0.1435
Schistosoma mansoni coup transcription factor 0.0043 0.0174 0.0178
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0014 0.0004 0.002
Schistosoma mansoni smad1 5 8 and 0.0017 0.0023 0.0023
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0144 0.0147
Plasmodium falciparum cysteine protease ATG4, putative 0.0049 0.0207 0.0953
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0083 0.0242
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0039 0.0152 0.0155
Leishmania major programmed cell death 6 protein-like protein 0.0069 0.0326 0.0951
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0174 0.0174
Echinococcus multilocularis programmed cell death protein 0.0072 0.0347 0.0347
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0267 0.1493 0.4369
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0049 0.0207 0.0601
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0301 1
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Echinococcus multilocularis cpg binding protein 0.0032 0.0111 0.0111
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0169 0.0918 0.1129
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0174 0.0178
Loa Loa (eye worm) hypothetical protein 0.0267 0.1493 0.1524
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0086 0.0427 0.0436
Echinococcus multilocularis cathepsin L 0.0217 0.1197 0.1197
Brugia malayi GPI-anchor transamidase 0.0035 0.0126 0.0128
Loa Loa (eye worm) hypothetical protein 0.0294 0.1649 0.1683
Trypanosoma cruzi kinesin, putative 0.0286 0.1607 0.164
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Onchocerca volvulus Cathepsin L homolog 0.0109 0.0561 0.069
Plasmodium vivax centrin-1, putative 0.0069 0.0326 0.1412
Brugia malayi Smad1 0.0017 0.0023 0.0023
Trypanosoma cruzi calmodulin, putative 0.0069 0.0326 0.0333
Brugia malayi RNA binding protein 0.0134 0.0708 0.0723
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0069 0.0326 0.1533
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0115 0.0598 0.175
Schistosoma mansoni ef hand domain family member A2 0.0069 0.0326 0.0333
Trypanosoma brucei mitochondrial calcium uptake 1 0.0069 0.0326 0.0951
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0032 0.0033
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0032 0.0033
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0144 0.0484
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0137 0.04
Mycobacterium tuberculosis Conserved protein 0.0038 0.0144 0.0484
Trypanosoma cruzi cysteine proteinase, putative 0.0217 0.1197 0.1221
Echinococcus multilocularis segment polarity protein dishevelled 0.0019 0.0032 0.0032
Echinococcus granulosus cathepsin l1 0.0375 0.2129 0.2173
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0069 0.0326 0.0333
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0137 0.04
Onchocerca volvulus 0.0375 0.2129 0.2619
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0375 0.2129 0.2173
Leishmania major hypothetical protein, conserved 0.007 0.0335 0.0975
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0144 0.0144
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0115 0.0598 0.0611
Brugia malayi hypothetical protein 0.0023 0.0055 0.0056
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0023 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0308 0.0315
Trypanosoma brucei I/6 autoantigen 0.0069 0.0326 0.0951
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.015 0.0803 0.235
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0004
Schistosoma mansoni Mername-AA248 (C02 family) 0.0401 0.2284 0.2331
Brugia malayi tailless protein 0.002 0.004 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0109 0.0561 0.2443
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0137 0.0137
Onchocerca volvulus Cathepsin L homolog 0.0375 0.2129 0.2619
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0097 0.0097
Echinococcus granulosus calpain 5 0.0401 0.2284 0.2331
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0109 0.0561 0.2443
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0217 0.1197 0.1221
Entamoeba histolytica cysteine proteinase, putative 0.0375 0.2129 1
Brugia malayi prolyl oligopeptidase family protein 0.0057 0.0256 0.0261
Entamoeba histolytica calpain large subunit domain III containing protein 0.0286 0.1607 0.7548
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0039 0.0152 0.0155
Echinococcus multilocularis Smad4 0.0017 0.0023 0.0022
Trypanosoma brucei calpain-like protein, putative 0.0401 0.2284 0.6682
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1046 0.1068
Schistosoma mansoni hypothetical protein 0.0067 0.0316 0.0322
Trypanosoma brucei centrin, putative 0.0069 0.0326 0.0951
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0109 0.0561 0.1642
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0174 0.0178
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0174 0.0178
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1289 0.3772
Brugia malayi calpain 7 0.0401 0.2284 0.2331
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1678 0.9797 1
Plasmodium falciparum serine repeat antigen 3 0.0109 0.0561 0.2622
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0174 0.0178
Entamoeba histolytica cysteine proteinase 1, putative 0.0217 0.1197 0.5622
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0001 0.0001
Echinococcus multilocularis neuropeptide s receptor 0.0493 0.2823 0.2823
Brugia malayi TAR-binding protein 0.0134 0.0708 0.0723
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0219 0.0636
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0004 0.0012
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0051 0.0219 0.1075
Leishmania major calmodulin, putative 0.0069 0.0326 0.0951
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0049 0.0207 0.0593
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0174 0.0178
Loa Loa (eye worm) hypothetical protein 0.0962 0.5586 0.5702
Brugia malayi Papain family cysteine protease containing protein 0.0109 0.0561 0.0573
Loa Loa (eye worm) heat shock protein 90 0.0035 0.0124 0.0127
Schistosoma mansoni zinc finger protein 0.002 0.004 0.0041
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.1046 0.1046
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0893 0.0912
Plasmodium vivax vivapain-3 0.0217 0.1197 0.5231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0561 0.1642
Schistosoma mansoni hypothetical protein 0.0039 0.0152 0.0155
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0069 0.0326 0.0951
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0144 0.0147
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0115 0.0598 0.1747
Trypanosoma cruzi conserved protein 0.0115 0.0598 0.0611
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0174 0.0178
Echinococcus multilocularis EF hand domain containing family member A2 0.0069 0.0326 0.0326
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0051 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0042 0.0165 0.0169
Echinococcus multilocularis calpain 7 (C02 family) 0.0401 0.2284 0.2284
Onchocerca volvulus 0.0096 0.0483 0.0595
Loa Loa (eye worm) hypothetical protein 0.0115 0.0598 0.0611
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0268 0.0772
Brugia malayi jmjC domain containing protein 0.0039 0.015 0.0153
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0137 0.04
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0301 0.1725
Onchocerca volvulus 0.0038 0.0144 0.0177
Loa Loa (eye worm) RNA binding protein 0.0134 0.0708 0.0723
Echinococcus granulosus GPCR family 2 0.0067 0.0316 0.0322
Trypanosoma brucei antigen, putative 0.0401 0.2284 0.6682
Schistosoma mansoni intermediate filament proteins 0.0086 0.0427 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus granulosus cathepsin l cysteine peptidase 0.0375 0.2129 0.2173
Onchocerca volvulus 0.0086 0.0427 0.0526
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0019 0.0032 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Brugia malayi Hsp90 protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0156 0.0159
Echinococcus multilocularis apoptotic protease activating factor 1 0.003 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.6682
Loa Loa (eye worm) hypothetical protein 0.004 0.0156 0.0159
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.0512 0.0512
Echinococcus multilocularis heat shock protein 0.0035 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0139 0.0139
Trypanosoma brucei centrin, putative 0.0069 0.0326 0.0951
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0126 0.0368
Brugia malayi cathepsin L precursor 0.0109 0.0561 0.0573
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0174 0.0178
Plasmodium falciparum serine repeat antigen 5 0.0109 0.0561 0.2622
Schistosoma mansoni Smad4 0.0017 0.0023 0.0023
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0057 0.0256 0.0746
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0041 0.0042
Onchocerca volvulus 0.0038 0.0144 0.0177
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0038 0.0144 0.0147
Brugia malayi Peptidase family C54 containing protein 0.0124 0.0654 0.0667
Schistosoma mansoni cathepsin F (C01 family) 0.0267 0.1493 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0109 0.0561 0.1642
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0174 0.0178
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0126 0.0364
Trypanosoma cruzi heat shock protein, putative 0.0014 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Brugia malayi hypothetical protein 0.0019 0.0032 0.0033
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0174 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Echinococcus multilocularis heat shock protein 90 0.0028 0.0083 0.0083
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0708 0.0723
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0115 0.0598 0.0611
Schistosoma mansoni nuclear hormone receptor 0.002 0.004 0.0041
Schistosoma mansoni dishevelled 0.0019 0.0032 0.0033
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Echinococcus granulosus cathepsin l1 0.0267 0.1493 0.1524
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0069 0.0326 0.1533
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0069 0.0326 0.0954
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.004 0.0041
Leishmania major centrin, putative 0.0069 0.0326 0.0951
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0057 0.0256 0.0746
Echinococcus multilocularis cysteine protease atg4b 0.0124 0.0654 0.0654
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.2331
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0174 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0126 0.0368
Entamoeba histolytica protein kinase, putative 0.0286 0.1607 0.7548
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1678 0.9797 1
Leishmania major centrin, putative 0.0069 0.0326 0.0951
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0013 0.0000066172 0.0000067546
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0144 0.0147
Leishmania major protein kinase, putative 0.0069 0.0326 0.0951
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0124 0.0654 0.1912
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0101 0.0285
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0708 0.0723
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0115 0.0598 0.175
Schistosoma mansoni alpha glucosidase 0.0037 0.0137 0.014
Echinococcus multilocularis calcium uptake protein 1 0.007 0.0335 0.0334
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0126 0.0364
Trypanosoma cruzi cysteine peptidase, putative 0.0217 0.1197 0.1221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0561 0.1642
Mycobacterium leprae Probable lipase LipE 0.0038 0.0144 1
Onchocerca volvulus 0.0069 0.0326 0.0401
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0124 0.0654 0.1912
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0144 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.1046 0.1046
Schistosoma mansoni hypothetical protein 0.0031 0.0101 0.0104
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0115 0.0598 0.1747
Onchocerca volvulus 0.002 0.004 0.005
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0708 0.0723
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Schistosoma mansoni calpain-2 (C02 family) 0.0115 0.0598 0.0611
Onchocerca volvulus Cathepsin L homolog 0.0375 0.2129 0.2619
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0056
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0174 0.0174
Schistosoma mansoni cathepsin S (C01 family) 0.0109 0.0561 0.0573
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0109 0.0561 0.1642
Entamoeba histolytica grainin, putative 0.007 0.0335 0.1571
Loa Loa (eye worm) hypothetical protein 0.0375 0.2129 0.2173
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0174 0.0178
Loa Loa (eye worm) TAR-binding protein 0.0134 0.0708 0.0723
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Loa Loa (eye worm) hypothetical protein 0.0109 0.0561 0.0573
Entamoeba histolytica cysteine protease, putative 0.0109 0.0561 0.2637
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0174 0.0178
Schistosoma mansoni hypothetical protein 0.0115 0.0598 0.0611
Trichomonas vaginalis calmodulin, putative 0.0072 0.0347 0.1015
Brugia malayi Cathepsin L-like precursor 0.0375 0.2129 0.2173
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0051 0.0219 0.094
Brugia malayi Papain family cysteine protease containing protein 0.0217 0.1197 0.1221
Loa Loa (eye worm) hypothetical protein 0.0109 0.0561 0.0573
Trypanosoma brucei heat shock protein 84, putative 0.0014 0.0004 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0137 0.04
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0097 0.0099
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0115 0.0598 0.0611
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.015 0.0803 0.082
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0174 0.0178
Trypanosoma brucei protein I/6 0.0069 0.0326 0.0951
Loa Loa (eye worm) DIX domain-containing protein 0.0019 0.0032 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0383 0.2175 0.2676
Trichomonas vaginalis calmodulin, putative 0.0069 0.0326 0.0954
Brugia malayi isocitrate dehydrogenase 0.0051 0.0219 0.0223
Brugia malayi cathepsin Z-like cysteine proteinase 0.0109 0.0561 0.0573
Brugia malayi Pre-SET motif family protein 0.0204 0.1124 0.1147
Trichomonas vaginalis calmodulin, putative 0.0069 0.0326 0.0954
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0165 0.0165
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0049 0.0207 0.0211
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.1046 0.1068
Loa Loa (eye worm) hypothetical protein 0.0086 0.0427 0.0436
Echinococcus granulosus segment polarity protein dishevelled 0.0019 0.0032 0.0033
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0069 0.0326 0.0954
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0109 0.0561 0.2443
Loa Loa (eye worm) prolyl oligopeptidase 0.0169 0.0918 0.0937
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0032 0.0032
Plasmodium falciparum serine repeat antigen 7 0.0109 0.0561 0.2622
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0144 0.0421
Leishmania major cysteine peptidase A (CPA) 0.0375 0.2129 0.6227
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0301 0.0307
Brugia malayi Papain family cysteine protease containing protein 0.0375 0.2129 0.2173
Trypanosoma brucei hypothetical protein, conserved 0.0069 0.0326 0.0951
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.0512 0.0523
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0109 0.0561 0.2622
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.004 0.0041
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0219 0.0223
Trypanosoma brucei caltractin, putative 0.0072 0.0347 0.1012
Echinococcus multilocularis neuronal calcium sensor 0.0069 0.0326 0.0326
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0219 0.0636
Brugia malayi calpain family protein 1 0.1077 0.6263 0.6393
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Echinococcus multilocularis calpain 5 0.0401 0.2284 0.2284
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0375 0.2129 0.2173
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0401 0.2284 0.2331
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Schistosoma mansoni cpg binding protein 0.0032 0.0111 0.0113
Schistosoma mansoni neuronal calcium sensor 0.0069 0.0326 0.0333
Trypanosoma brucei glucosidase, putative 0.0037 0.0137 0.0396
Onchocerca volvulus 0.0267 0.1493 0.1837
Brugia malayi Calmodulin-like protein 0.0069 0.0326 0.0333
Toxoplasma gondii heat shock protein 90, putative 0.0035 0.0124 0.0352
Echinococcus multilocularis GPCR, family 2 0.0067 0.0316 0.0316
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0069 0.0326 0.0333
Echinococcus multilocularis lamin 0.0086 0.0427 0.0427
Schistosoma mansoni jumonji domain containing protein 0.008 0.0391 0.0399
Brugia malayi jmjC domain containing protein 0.01 0.0512 0.0523
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0144 0.0421
Schistosoma mansoni calcium binding atopy-related autoantigen 0.007 0.0335 0.0341
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.1197 0.3501
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0013 0.0000066172 0.0000067546
Toxoplasma gondii EF hand domain-containing protein 0.0069 0.0326 0.0943
Plasmodium falciparum endoplasmin, putative 0.0021 0.0046 0.0195
Schistosoma mansoni hemoglobinase (C13 family) 0.015 0.0803 0.082
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0893 0.0893
Entamoeba histolytica peptidase, C54 family 0.0049 0.0207 0.0971
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0174 0.0178
Echinococcus granulosus cysteine protease 0.0217 0.1197 0.1221
Onchocerca volvulus Alhambra homolog 0.0031 0.0101 0.0125
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Echinococcus multilocularis calmodulin 0.0069 0.0326 0.0326
Schistosoma mansoni dep domain containing protein 0.0019 0.0032 0.0033
Onchocerca volvulus 0.0031 0.0101 0.0124
Echinococcus granulosus cathepsin b 0.1678 0.9797 1
Giardia lamblia Cathepsin B precursor 0.0109 0.0561 0.1435
Loa Loa (eye worm) cathepsin B 0.0594 0.3418 0.3488
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.015 0.0803 0.235
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Trichomonas vaginalis calpain, putative 0.0115 0.0598 0.175
Brugia malayi steroid hormone receptor 0.0043 0.0174 0.0178
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Giardia lamblia Cathepsin B precursor 0.0109 0.0561 0.1435
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Brugia malayi nuclear receptor RXR 0.0023 0.0055 0.0056
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0217 0.1197 0.1221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0561 0.1642
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0101 0.0426
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1077 0.6263 0.6393
Onchocerca volvulus 0.007 0.0335 0.0411
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.015 0.0803 0.235
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.015 0.0803 0.235
Loa Loa (eye worm) DR-78 0.002 0.004 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0401 0.2284 0.2331
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0144 0.0418
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0051 0.0219 0.0223
Plasmodium falciparum heat shock protein 90 0.0035 0.0124 0.0565
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0301 0.0301
Entamoeba histolytica hypothetical protein, conserved 0.007 0.0335 0.1571
Trypanosoma brucei centrin-3 0.0072 0.0347 0.1012
Echinococcus granulosus cpg binding protein 0.0032 0.0111 0.0113
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0069 0.0326 0.0326
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.1346 1
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.0124 0.0584
Echinococcus multilocularis calpain family protein 1, d 0.0791 0.4578 0.4577
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0174 0.0178
Schistosoma mansoni cpg binding protein 0.0032 0.0111 0.0113
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0109 0.0561 0.2622
Echinococcus multilocularis calpain A 0.1148 0.6677 0.6677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus granulosus apoptotic protease activating factor 1 0.003 0.0097 0.0099
Trypanosoma cruzi cruzipain precursor, putative 0.0108 0.0556 0.0568
Echinococcus multilocularis cathepsin L 0.0109 0.0561 0.0561
Loa Loa (eye worm) calpain 0.0401 0.2284 0.2331
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0144 0.0484
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0124 0.0654 0.0667
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Entamoeba histolytica calcium binding family protein 0.0069 0.0326 0.1533
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0051 0.0219 0.0636
Plasmodium falciparum serine repeat antigen 9 0.0109 0.0561 0.2622
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0109 0.0561 0.1642
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0137 0.04
Loa Loa (eye worm) isocitrate dehydrogenase 0.0051 0.0219 0.0223
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0067 0.0316 0.0322
Brugia malayi Cathepsin L-like precursor 0.0375 0.2129 0.2173
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0031 0.0032
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0101 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0217 0.1197 0.3499
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Toxoplasma gondii cathepsin CPC2 0.0109 0.0561 0.1632
Onchocerca volvulus 0.0375 0.2129 0.2619
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0079 0.008
Trichomonas vaginalis calpain, putative 0.0115 0.0598 0.175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0174 0.0178
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0144 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0109 0.0561 0.1642
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0109 0.0561 0.0573
Brugia malayi ecdysteroid receptor 0.0043 0.0174 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0174 0.0178
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0049 0.0207 0.0211
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0101 0.0285
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0893 0.0912
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0109 0.0561 0.2443
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus granulosus neuropeptide s receptor 0.0493 0.2823 0.2882
Trypanosoma cruzi cysteine peptidase, putative 0.0375 0.2129 0.2173
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0174 0.0178
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.007 0.0335 0.0341
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Brugia malayi hypothetical protein 0.0044 0.0177 0.0181
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Brugia malayi RNA recognition motif domain containing protein 0.0134 0.0708 0.0723
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0067 0.0316 0.0316
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0301 0.0869
Schistosoma mansoni calmodulin 0.0069 0.0326 0.0333
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0174 0.0178
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0084 0.0418 0.0427
Loa Loa (eye worm) beta-lactamase 0.0038 0.0144 0.0147
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Schistosoma mansoni calpain-7 (C02 family) 0.0401 0.2284 0.2331
Onchocerca volvulus 0.0038 0.0144 0.0177
Trypanosoma cruzi cysteine peptidase, putative 0.0375 0.2129 0.2173
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.1412 0.1441
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Leishmania major i/6 autoantigen-like protein 0.0069 0.0326 0.0951
Brugia malayi Cathepsin L-like precursor 0.0375 0.2129 0.2173
Brugia malayi Phospholipase A2 family protein 0.0294 0.1649 0.1683
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0001 0.0004
Echinococcus granulosus calbindin 32 0.007 0.0335 0.0341
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Trichomonas vaginalis calcium binding protein, putative 0.0069 0.0326 0.0954
Entamoeba histolytica cysteine proteinase 2 0.0217 0.1197 0.5622
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0401 0.2284 0.2331
Loa Loa (eye worm) hypothetical protein 0.0124 0.0654 0.0667
Trypanosoma cruzi cruzipain precursor, putative 0.0375 0.2129 0.2173
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0109 0.0561 0.2443
Entamoeba histolytica cysteine proteinase, putative 0.0217 0.1197 0.5622
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0056
Plasmodium falciparum centrin-1 0.0069 0.0326 0.1516
Echinococcus granulosus inhibitor of apoptosis protein 0.0039 0.0152 0.0155
Trypanosoma brucei calpain, putative 0.0115 0.0598 0.1747
Echinococcus granulosus caspase 2 0.003 0.0097 0.0099
Giardia lamblia Hypothetical protein 0.0109 0.0561 0.1435
Leishmania major calmodulin-like protein 0.0069 0.0326 0.0951
Echinococcus multilocularis cysteine protease 0.0375 0.2129 0.2128
Brugia malayi hypothetical protein 0.002 0.004 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0144 0.0147
Brugia malayi latrophilin 2 splice variant baaae 0.0145 0.0774 0.079
Schistosoma mansoni heat shock protein 0.0035 0.0124 0.0127
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0174 0.0178
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.0561 0.0573
Schistosoma mansoni calpain C (C02 family) 0.0401 0.2284 0.2331
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0561 0.1642
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.004 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Plasmodium vivax SET domain protein, putative 0.003 0.0097 0.0406
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.015 0.0803 0.235
Trypanosoma cruzi centrin, putative 0.0072 0.0347 0.0354
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0033
Brugia malayi MH2 domain containing protein 0.0017 0.0023 0.0023
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.0124 0.0584
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0115 0.0598 0.0611
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0109 0.0561 0.0573
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Entamoeba histolytica cysteine proteinase, putative 0.0217 0.1197 0.5622
Echinococcus multilocularis isocitrate dehydrogenase 0.0051 0.0219 0.0219
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0124 0.0127
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Giardia lamblia Cathepsin L precursor 0.0109 0.0561 0.1435
Echinococcus granulosus cathepsin L 0.0109 0.0561 0.0573
Onchocerca volvulus 0.0232 0.1289 0.1586
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0301 0.0307
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0144 0.2805
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Loa Loa (eye worm) hypothetical protein 0.0212 0.1169 0.1193
Schistosoma mansoni hemoglobinase (C13 family) 0.015 0.0803 0.082
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0115 0.0598 0.0611
Brugia malayi Endoplasmin precursor 0.0035 0.0124 0.0127
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0124 0.0654 0.1909
Plasmodium vivax serine-repeat antigen (SERA) 0.0109 0.0561 0.2443
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.004 0.0041
Brugia malayi N-terminal motif family protein 0.0383 0.2175 0.222
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0165 0.0169
Entamoeba histolytica hypothetical protein 0.0109 0.0561 0.2637
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0023 0.0023
Trichomonas vaginalis calmodulin, putative 0.0069 0.0326 0.0954
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0375 0.2129 0.6228
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0174 0.0174
Brugia malayi conserved hypotetical protein 0.002 0.004 0.0041
Brugia malayi prolyl oligopeptidase family protein 0.0169 0.0918 0.0937
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0001 0.0006
Trypanosoma brucei cysteine peptidase, putative 0.0115 0.0598 0.1747
Echinococcus multilocularis EF hand domain containing family member A2 0.007 0.0335 0.0334
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Schistosoma mansoni endoplasmin 0.0035 0.0124 0.0127
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0056
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0032 0.0033
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1146 0.6668 0.6807
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0109 0.0561 0.1435
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0174 0.0178
Brugia malayi Pre-SET motif family protein 0.003 0.0097 0.0099
Brugia malayi Bromodomain containing protein 0.0031 0.0101 0.0104
Brugia malayi cathepsin L-like precursor 0.0267 0.1493 0.1524
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0057 0.0256 0.0256
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0109 0.0561 0.0573
Entamoeba histolytica cysteine proteinase, putative 0.0267 0.1493 0.7015
Entamoeba histolytica cysteine protease, putative 0.0109 0.0561 0.2637
Echinococcus granulosus calpain 7 C02 family 0.0401 0.2284 0.2331
Giardia lamblia Cysteine protease 0.0109 0.0561 0.1435
Echinococcus multilocularis programmed cell death protein 0.0072 0.0347 0.0347
Onchocerca volvulus Phospholipase A2 homolog 0.1394 0.8128 1
Brugia malayi hypothetical protein 0.002 0.004 0.0041
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0028 0.0083 0.5
Entamoeba histolytica cysteine protease, putative 0.0109 0.0561 0.2637
Loa Loa (eye worm) calmodulin-like protein 0.0069 0.0326 0.0333
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0137 0.014
Schistosoma mansoni hypothetical protein 0.0067 0.0316 0.0322
Echinococcus granulosus heat shock protein 0.0035 0.0124 0.0127
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0097 0.0271
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0069 0.0326 0.0401
Schistosoma mansoni neuronal calcium sensor 0.0069 0.0326 0.0333
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0051 0.0219 0.0223
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Schistosoma mansoni hypothetical protein 0.0899 0.5213 0.5322
Echinococcus granulosus cysteine protease atg4b 0.0124 0.0654 0.0667
Onchocerca volvulus 0.003 0.0097 0.0119
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Giardia lamblia Cathepsin L-like protease 0.0109 0.0561 0.1435
Brugia malayi nuclear receptor RXR 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0791 0.4578 0.4673
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0055 0.0056
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0101 0.0104
Echinococcus granulosus Dipeptidyl peptidase 9 0.0057 0.0256 0.0261
Echinococcus granulosus cathepsin L cysteine proteinase 0.0375 0.2129 0.2173
Loa Loa (eye worm) heat shock protein 75 0.0014 0.0004 0.0004
Onchocerca volvulus Huntingtin homolog 0.0262 0.1463 0.18
Entamoeba histolytica grainin 2 0.0072 0.0347 0.163
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0109 0.0561 0.2637
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0109 0.0561 0.1642
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Loa Loa (eye worm) intermediate filament protein 0.0086 0.0427 0.0436
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0137 0.014
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0192 0.0196
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0057 0.0256 0.0262
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0109 0.0561 0.2443
Loa Loa (eye worm) hypothetical protein 0.0031 0.0101 0.0104
Giardia lamblia Cathepsin B precursor 0.0109 0.0561 0.1435
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.004 0.005
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0174 0.0178
Brugia malayi Latrophilin receptor protein 2 0.0067 0.0316 0.0322
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0169 0.0918 0.0937
Leishmania major cathepsin L-like protease 0.0375 0.2129 0.6227
Schistosoma mansoni hypothetical protein 0.0145 0.0774 0.079
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0057 0.0256 0.0262
Brugia malayi cathepsin F-like cysteine proteinase 0.0109 0.0561 0.0573
Schistosoma mansoni cathepsin F (C01 family) 0.0375 0.2129 0.2173
Trypanosoma brucei heat shock protein, putative 0.0035 0.0124 0.036
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.004 0.0041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Brugia malayi nuclear hormone receptor 0.002 0.004 0.0041
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0191 0.1046 0.1068
Trichomonas vaginalis calmodulin-2, putative 0.0069 0.0326 0.0954
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0137 0.014
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0023 0.0023
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Toxoplasma gondii cathepsin CPC1 0.0109 0.0561 0.1632
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0115 0.0598 0.0611
Trypanosoma brucei calpain, putative 0.0115 0.0598 0.1747
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0155
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0109 0.0561 0.0573
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0174 0.0174
Schistosoma mansoni cathepsin B (C01 family) 0.0109 0.0561 0.0573
Mycobacterium ulcerans hypothetical protein 0.0038 0.0144 0.2805
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Echinococcus multilocularis peregrin 0.0031 0.0101 0.0101
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0014 0.0004 0.0004
Schistosoma mansoni mitochondrial solute carrier 0.0069 0.0326 0.0333
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0137 0.014
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0069 0.0326 0.0333
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0101 0.0104
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0124 0.0127
Loa Loa (eye worm) fibroinase 0.0375 0.2129 0.2173
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.0611
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0401 0.2284 0.2331
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0115 0.0598 0.175
Brugia malayi programmed cell death protein 6 0.0069 0.0326 0.0333
Loa Loa (eye worm) hypothetical protein 0.0676 0.39 0.3981
Trypanosoma cruzi cysteine proteinase, putative 0.0217 0.1197 0.1221
Brugia malayi nuclear receptor NHR-67 0.002 0.004 0.0041
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0126 0.0128
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0019 0.0032 0.0039
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0097 0.0097
Trichomonas vaginalis heat shock protein, putative 0.0035 0.0124 0.0364
Leishmania major hypothetical protein, conserved 0.0038 0.0144 0.0418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0561 0.1642
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0144 0.0421
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.004 0.0041
Brugia malayi Cathepsin L-like cysteine proteinase 0.0267 0.1493 0.1524
Echinococcus granulosus heat shock protein 90 0.0035 0.0124 0.0127
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1124 0.1147
Schistosoma mansoni calpain-7 (C02 family) 0.0401 0.2284 0.2331
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0217 0.1197 0.1221
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0174 0.0178
Echinococcus granulosus cathepsin b 0.1678 0.9797 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.004 0.0041
Trichomonas vaginalis calmodulin, putative 0.0069 0.0326 0.0954
Brugia malayi nuclear receptor NHR-88 0.002 0.004 0.0041
Leishmania major heat shock protein, putative 0.0014 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0055 0.0056
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0144 0.0421
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1046 0.1068
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0561 0.1642
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1678 0.9797 1
Plasmodium vivax unspecified product 0.0109 0.0561 0.2443
Loa Loa (eye worm) hypothetical protein 0.0267 0.1493 0.1524
Echinococcus multilocularis Peptidase C54 0.0124 0.0654 0.0654
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0217 0.1197 0.3499
Leishmania major hypothetical protein, conserved 0.0115 0.0598 0.1747
Trichomonas vaginalis hypothetical protein 0.0115 0.0598 0.175
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0598 0.175
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.1046 0.1068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0561 0.1642
Echinococcus granulosus lamin 0.0086 0.0427 0.0436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Trypanosoma cruzi hypothetical protein 0.0013 0.0000066172 0.0000067546
Brugia malayi ecdysone receptor 0.002 0.004 0.0041
Trichomonas vaginalis calcium binding protein, putative 0.0069 0.0326 0.0954
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0032 0.0032
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0109 0.0561 0.2443
Echinococcus granulosus cathepsin L cysteine protease 0.0217 0.1197 0.1221
Brugia malayi calpain family protein 1 0.1077 0.6263 0.6393
Leishmania major hypothetical protein, conserved 0.0069 0.0326 0.0951
Brugia malayi MH1 domain containing protein 0.0017 0.0023 0.0023
Mycobacterium ulcerans lipase LipD 0.0038 0.0144 0.2805
Echinococcus granulosus endoplasmin 0.0028 0.0083 0.0085
Loa Loa (eye worm) EF hand family protein 0.0069 0.0326 0.0333
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0000066172 0.0000067546
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0046 0.0134
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0039 0.0152 0.0152
Trypanosoma brucei Calpain-like protein CALP1.3 0.0115 0.0598 0.1747
Leishmania major hypothetical protein, unknown function 0.0115 0.0598 0.1747
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0049 0.0207 0.0601
Brugia malayi cathepsin L-like cysteine proteinase 0.0109 0.0561 0.0573
Schistosoma mansoni reticulocalbin 0.007 0.0335 0.0341
Plasmodium vivax endoplasmin, putative 0.0035 0.0124 0.0526
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.004 0.004
Brugia malayi beta-lactamase family protein 0.0038 0.0144 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Onchocerca volvulus 0.0375 0.2129 0.2619
Trichomonas vaginalis calcium binding proteins, putative 0.0069 0.0326 0.0954
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0174 0.0178
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0041 0.0042
Echinococcus granulosus calpain 0.0401 0.2284 0.2331
Brugia malayi intermediate filament protein 0.0086 0.0427 0.0436
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0109 0.0561 0.0573
Echinococcus multilocularis heat shock protein 90 0.0035 0.0124 0.0124
Trichomonas vaginalis calcium binding protein, putative 0.0069 0.0326 0.0954
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0069 0.0326 0.0951
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0124 0.0654 0.1912
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1678 0.9797 1
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0028 0.0083 0.0239
Trypanosoma brucei calpain-like protein, putative 0.0401 0.2284 0.6682
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0294 0.03
Loa Loa (eye worm) hypothetical protein 0.0109 0.0561 0.0573
Brugia malayi cathepsin Z-like cysteine proteinase 0.0109 0.0561 0.0573
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.004 0.004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0212 0.1169 0.1193
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.015 0.0153
Plasmodium vivax unspecified product 0.0217 0.1197 0.5231
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0126 0.0571
Loa Loa (eye worm) hypothetical protein 0.0053 0.023 0.0235
Brugia malayi PHD-finger family protein 0.0031 0.0101 0.0104
Brugia malayi MH2 domain containing protein 0.0253 0.1412 0.1441
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0115 0.0598 0.0611
Brugia malayi Calcitonin receptor-like protein seb-1 0.0212 0.1169 0.1193
Brugia malayi Cathepsin L-like precursor 0.0108 0.0556 0.0568
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0191 0.1046 0.1068
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0039 0.0152 0.0155
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0101 0.0101
Onchocerca volvulus 0.003 0.0097 0.0119
Trypanosoma brucei calmodulin, putative 0.007 0.0335 0.0975
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0174 0.0178
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0174 0.0178
Brugia malayi CXXC zinc finger family protein 0.0031 0.0101 0.0103
Entamoeba histolytica peptidase, C54 family 0.0049 0.0207 0.0971
Echinococcus granulosus smad 0.0017 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus multilocularis inhibitor of apoptosis protein 0.0039 0.0152 0.0152
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0109 0.0561 0.2443
Toxoplasma gondii heat shock protein HSP90 0.0035 0.0124 0.0352
Echinococcus multilocularis cathepsin L cysteine protease 0.0375 0.2129 0.2128
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0708 0.0723
Giardia lamblia PHD finger protein 15 0.0031 0.0101 0.0056
Onchocerca volvulus Cell death protein 3 homolog 0.003 0.0097 0.0119
Giardia lamblia Heat shock protein HSP 90-alpha 0.0035 0.0124 0.0124
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0109 0.0561 0.1435
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1146 0.6668 0.6668
Brugia malayi Nuclear hormone receptor E75 0.002 0.004 0.0041
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0055 0.0056
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0301 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0174 0.0178
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0099
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0174 0.0174
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0124 0.036
Onchocerca volvulus 0.002 0.004 0.005
Onchocerca volvulus 0.0109 0.0561 0.069
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0023 0.0023
Trypanosoma cruzi caltractin, putative 0.0069 0.0326 0.0333
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0174 0.0174
Schistosoma mansoni inhibitor of apoptosis protein 0.0039 0.0152 0.0155
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0137 0.0642
Brugia malayi EF hand family protein 0.007 0.0335 0.0341
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0000066172 0.0000067546
Schistosoma mansoni hypothetical protein 0.0069 0.0326 0.0333
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1046 0.1068
Trypanosoma cruzi cysteine protease, putative 0.0217 0.1197 0.1221
Entamoeba histolytica peptidase, C54 family 0.0049 0.0207 0.0971
Onchocerca volvulus 0.0043 0.0174 0.0214
Brugia malayi beta-lactamase family protein 0.0038 0.0144 0.0147
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0137 0.04
Plasmodium falciparum calpain 0.0115 0.0598 0.2796
Giardia lamblia Cathepsin B precursor 0.0594 0.3418 1
Loa Loa (eye worm) calpain family protein 1 0.1077 0.6263 0.6393
Echinococcus granulosus segment polarity protein dishevelled 0.0019 0.0032 0.0033
Trypanosoma cruzi calmodulin, putative 0.0069 0.0326 0.0333
Schistosoma mansoni hypothetical protein 0.003 0.0097 0.0099
Echinococcus multilocularis X box binding protein 1 0.0303 0.1705 0.1705
Echinococcus granulosus EF hand domain containing family member A2 0.007 0.0335 0.0341
Onchocerca volvulus 0.0039 0.0152 0.0187
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0055 0.0056
Loa Loa (eye worm) peptidase C13 family protein 0.015 0.0803 0.082
Schistosoma mansoni hypothetical protein 0.0069 0.0326 0.0333
Echinococcus multilocularis hypothetical protein 0.0401 0.2284 0.2284
Loa Loa (eye worm) Smad1 0.0017 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Giardia lamblia Hypothetical protein 0.0109 0.0561 0.1435
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Schistosoma mansoni autophagin-1 (C54 family) 0.0124 0.0654 0.0667
Onchocerca volvulus Legumain homolog 0.015 0.0803 0.0988
Echinococcus granulosus cathepsin L 0.0217 0.1197 0.1221
Schistosoma mansoni alpha-glucosidase 0.0142 0.0758 0.0774
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.004 0.004
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Entamoeba histolytica peptidase, C54 family 0.0124 0.0654 0.3071
Giardia lamblia Cathepsin B precursor 0.0109 0.0561 0.1435
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0109 0.0561 0.2443
Schistosoma mansoni ras GTP exchange factor 0.0013 0.0000066172 0.0000067546
Plasmodium vivax serine-repeat antigen (SERA) 0.0109 0.0561 0.2443
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0169 0.0918 0.0918
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0126 0.059
Schistosoma mansoni lamin 0.0086 0.0427 0.0436
Entamoeba histolytica cysteine proteinase, putative 0.0375 0.2129 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.004 0.004
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0109 0.0561 0.2637
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0115 0.0598 0.175
Plasmodium falciparum serine repeat antigen 4 0.0109 0.0561 0.2622
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0124 0.0654 0.1912
Schistosoma mansoni nuclear receptor 0.002 0.004 0.0041
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0267 0.1493 0.1524
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0219 0.0628
Brugia malayi beta-lactamase 0.0038 0.0144 0.0147
Trypanosoma cruzi I/6 autoantigen, putative 0.0069 0.0326 0.0333
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0144 0.0484
Loa Loa (eye worm) hypothetical protein 0.0267 0.1493 0.1524
Plasmodium vivax vivapain-2 0.0375 0.2129 0.9318
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0144 0.0484
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0174 0.0178
Giardia lamblia Cathepsin B precursor 0.0594 0.3418 1
Echinococcus multilocularis caspase 2 0.003 0.0097 0.0097
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0115 0.0598 0.0611
Loa Loa (eye worm) latrophilin receptor protein 2 0.0067 0.0316 0.0322
Giardia lamblia Cathepsin B precursor 0.0594 0.3418 1
Schistosoma mansoni heat shock protein 0.0035 0.0124 0.0127
Plasmodium vivax unspecified product 0.0108 0.0556 0.2422
Echinococcus multilocularis thyroid hormone receptor alpha 0.0043 0.0174 0.0174
Toxoplasma gondii hypothetical protein 0.0115 0.0598 0.174
Plasmodium falciparum cysteine proteinase falcipain 1 0.0217 0.1197 0.5613
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0137 0.0642
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.015 0.0803 0.235
Onchocerca volvulus Cathepsin F homolog 0.0375 0.2129 0.2619
Brugia malayi nuclear receptor NHR-88 0.0043 0.0174 0.0178
Loa Loa (eye worm) endoplasmin 0.0035 0.0124 0.0127
Echinococcus granulosus calmodulin 0.0069 0.0326 0.0333
Brugia malayi EF hand family protein 0.0069 0.0326 0.0333
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0144 0.0147
Mycobacterium tuberculosis Conserved protein 0.0038 0.0144 0.0484
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1146 0.6668 0.6807
Brugia malayi hypothetical protein 0.0262 0.1463 0.1493
Trypanosoma cruzi kinesin, putative 0.0286 0.1607 0.164
Loa Loa (eye worm) hypothetical protein 0.1077 0.6263 0.6393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0267 0.1493 0.4369
Brugia malayi hypothetical protein 0.0019 0.0032 0.0033
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0109 0.0561 0.2443
Giardia lamblia Cathepsin L-like protease 0.0109 0.0561 0.1435
Loa Loa (eye worm) ctsf protein 0.0375 0.2129 0.2173
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.0083 0.0085
Trypanosoma brucei hypothetical protein 0.0115 0.0598 0.1747
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0004
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0083 0.0242
Leishmania major calpain family cysteine protease-like protein 0.0115 0.0598 0.1747
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0126 0.0128
Schistosoma mansoni lamin 0.0086 0.0427 0.0436
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Trypanosoma cruzi cysteine peptidase, putative 0.0375 0.2129 0.2173
Plasmodium vivax calpain, putative 0.0401 0.2284 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0594 0.3418 0.3489
Giardia lamblia Cysteine protease 0.0109 0.0561 0.1435
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0115 0.0598 0.175
Plasmodium falciparum cysteine proteinase falcipain 3 0.0375 0.2129 1
Loa Loa (eye worm) calpain D 0.0115 0.0598 0.0611
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0124 0.0654 0.1912
Entamoeba histolytica calmodulin, putative 0.0069 0.0326 0.1533
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0067 0.0316 0.0322
Schistosoma mansoni centrin-related 0.0069 0.0326 0.0333
Trypanosoma brucei calpain-like protein, putative 0.0401 0.2284 0.6682
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0375 0.2129 0.6228
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0057 0.0256 0.0738
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.004 0.0041
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0124 0.0654 0.1909
Brugia malayi Cathepsin L-like precursor 0.0267 0.1493 0.1524
Toxoplasma gondii calcium-dependent protein kinase 0.007 0.0335 0.0967
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0174 0.0178
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.004 0.0041
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0174 0.0178
Trypanosoma cruzi Heat shock protein 83, putative 0.0035 0.0124 0.0127
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.015 0.0153
Entamoeba histolytica calcium-binding protein, putative 0.0069 0.0326 0.1533
Schistosoma mansoni caspase-7 (C14 family) 0.003 0.0097 0.0099
Trypanosoma cruzi centrin, putative 0.0072 0.0347 0.0354
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0301 0.0877
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0172 0.0176
Plasmodium falciparum serine repeat antigen 6 0.0109 0.0561 0.2622
Loa Loa (eye worm) hypothetical protein 0.0109 0.0561 0.0573
Schistosoma mansoni neuronal calcium sensor 0.0069 0.0326 0.0333
Giardia lamblia Cysteine protease 0.0109 0.0561 0.1435
Brugia malayi calpain D 0.0115 0.0598 0.0611
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0219 0.0219
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0014 0.0004 0.0005
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0144 0.0147
Echinococcus granulosus calpain A 0.0401 0.2284 0.2331
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0126 0.0533
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0109 0.0561 0.0573
Entamoeba histolytica cysteine proteinase, putative 0.0217 0.1197 0.5622
Entamoeba histolytica cysteine protease, putative 0.0217 0.1197 0.5622
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.015 0.0153
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0109 0.0561 0.1642
Loa Loa (eye worm) hypothetical protein 0.0038 0.0144 0.0147
Loa Loa (eye worm) hypothetical protein 0.0038 0.0144 0.0147
Entamoeba histolytica calpain family cysteine protease, putative 0.0115 0.0598 0.281
Plasmodium falciparum serine repeat antigen 2 0.0109 0.0561 0.2622
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0041
Trypanosoma cruzi cysteine peptidase, putative 0.0375 0.2129 0.2173
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0069 0.0326 0.0333
Onchocerca volvulus 0.0375 0.2129 0.2619
Entamoeba histolytica cysteine protease, putative 0.0109 0.0561 0.2637
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0051 0.0219 0.0223
Schistosoma mansoni heat shock protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0001 0.0004
Brugia malayi Cathepsin L-like precursor 0.0375 0.2129 0.2173
Loa Loa (eye worm) follicle stimulating hormone receptor 0.024 0.1332 0.136
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0144 0.0484
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.004 0.004
Schistosoma mansoni alpha-glucosidase 0.0142 0.0758 0.0774
Brugia malayi cathepsin B-like cysteine proteinase 0.1678 0.9797 1
Echinococcus multilocularis segment polarity protein dishevelled 0.0019 0.0032 0.0032
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0109 0.0561 0.0573
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0594 0.3418 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0109 0.0561 0.1642
Loa Loa (eye worm) hypothetical protein 0.0109 0.0561 0.0573
Plasmodium vivax vivapain-2 0.0375 0.2129 0.9318
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0069 0.0326 0.0326
Trypanosoma cruzi centrin-3 0.0072 0.0347 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0326 0.0954
Echinococcus granulosus neuropeptide receptor A26 0.0493 0.2823 0.2882
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0217 0.1197 0.1221
Toxoplasma gondii troponin c, isotype gamma, putative 0.0069 0.0326 0.0943
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0069 0.0326 0.0333
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0124 0.0654 0.0667
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0097 0.0099
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Giardia lamblia Cathepsin L precursor 0.0109 0.0561 0.1435
Toxoplasma gondii preprocathepsin c precursor, putative 0.0109 0.0561 0.1632
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0375 0.2129 0.6227
Loa Loa (eye worm) hypothetical protein 0.0109 0.0561 0.0573
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Brugia malayi Cell death protein 3 precursor 0.003 0.0097 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0174 0.0178
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0055 0.0056
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0109 0.0561 0.1435
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0174 0.0178
Leishmania major kinesin, putative 0.0286 0.1607 0.4699
Echinococcus granulosus intermediate filament protein 0.0086 0.0427 0.0436
Loa Loa (eye worm) hypothetical protein 0.0035 0.0126 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0375 0.2129 0.6228
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0067 0.0316 0.0322
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.004 0.005
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0174 0.0178
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0019 0.0032 0.0032
Echinococcus granulosus calpain A 0.1148 0.6677 0.6815
Echinococcus multilocularis smad 0.0017 0.0023 0.0022
Brugia malayi follicle stimulating hormone receptor 0.024 0.1332 0.136
Schistosoma mansoni rab 0.0069 0.0326 0.0333
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0097 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0097 0.0099
Trichomonas vaginalis calmodulin, putative 0.0069 0.0326 0.0954
Loa Loa (eye worm) hypothetical protein 0.0145 0.0774 0.079
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0144 0.0421
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0893 0.0893
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2284 0.6682
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0039 0.0152 0.0155
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0401 0.2284 0.2331
Echinococcus granulosus neurocalcin 0.0069 0.0326 0.0333
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0893 0.0912
Schistosoma mansoni calmodulin related calcium binding protein 0.0069 0.0326 0.0333
Echinococcus granulosus tar DNA binding protein 0.0134 0.0708 0.0723
Entamoeba histolytica cysteine protease, putative 0.0109 0.0561 0.2637
Trichomonas vaginalis calcineurin B subunit, putative 0.007 0.0335 0.0979
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.015 0.0803 0.235
Echinococcus granulosus programmed cell death protein 0.0072 0.0347 0.0354
Mycobacterium ulcerans beta-lactamase 0.0038 0.0144 0.2805
Trypanosoma brucei Calpain-like protein 1.1 0.0115 0.0598 0.1747
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0174 0.0178
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0174 0.0178
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0212 0.1169 0.1193
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0087 0.0088
Toxoplasma gondii cathepsin B 0.0594 0.3418 1
Echinococcus multilocularis lamin dm0 0.0086 0.0427 0.0427
Brugia malayi Intermediate filament tail domain containing protein 0.0086 0.0427 0.0436
Onchocerca volvulus Deterin homolog 0.0039 0.0152 0.0187
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0126 0.0128
Schistosoma mansoni hypothetical protein 0.0899 0.5213 0.5322
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0051 0.0219 0.1009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0174 0.0178
Brugia malayi Papain family cysteine protease containing protein 0.0217 0.1197 0.1221
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0109 0.0561 0.1642
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0097 0.0099
Brugia malayi Cytochrome P450 family protein 0.0027 0.0079 0.008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0174 0.0214
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0109 0.0561 0.0573
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.1412 0.1441
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0174 0.0178
Trypanosoma brucei calmodulin, putative 0.0069 0.0326 0.0951
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0124 0.0654 0.0667
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0069 0.0326 0.1412
Schistosoma mansoni cathepsin s 0.0108 0.0556 0.0568
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0174 0.0178
Leishmania major heat shock protein 83-1 0.0035 0.0124 0.036
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0178
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0134 0.0708 0.0723
Leishmania major calpain protease-like protein 0.0115 0.0598 0.1747
Brugia malayi Cathepsin L-like precursor 0.0375 0.2129 0.2173
Trichomonas vaginalis myosin light chain 1, putative 0.0069 0.0326 0.0954
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0069 0.0326 0.0333
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0023 0.0023
Toxoplasma gondii calmodulin CAM1 0.007 0.0335 0.0967
Loa Loa (eye worm) hypothetical protein 0.0108 0.0556 0.0568
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0262 0.1463 0.1493
Echinococcus multilocularis calbindin 32 0.007 0.0335 0.0334
Echinococcus granulosus calcium uptake protein 1 0.007 0.0335 0.0341
Trichomonas vaginalis calmodulin, putative 0.0069 0.0326 0.0954
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0001 0.0004
Onchocerca volvulus 0.0375 0.2129 0.2619
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.1197 0.3501
Loa Loa (eye worm) hypothetical protein 0.0383 0.2175 0.222
Brugia malayi Isocitrate dehydrogenase 0.0051 0.0219 0.0223
Schistosoma mansoni centrin 0.0069 0.0326 0.0333
Brugia malayi nuclear hormone receptor 0.0043 0.0174 0.0178
Toxoplasma gondii hypothetical protein 0.0019 0.0032 0.0081
Trypanosoma cruzi calmodulin, putative 0.0069 0.0326 0.0333
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0057 0.0256 0.0262
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.0598 0.1747
Entamoeba histolytica cysteine proteinase, putative 0.0217 0.1197 0.5622
Schistosoma mansoni reticulocalbin 0.0069 0.0326 0.0333
Schistosoma mansoni dishevelled 0.0019 0.0032 0.0033
Trypanosoma cruzi I/6 autoantigen, putative 0.0069 0.0326 0.0333
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0014 0.0004 0.0004

Activities

Activity type Activity value Assay description Source Reference
TC50 (ADMET) = 146 uM Cytotoxicity in mouse RAW264.7 cells after 24 hrs by MTT assay ChEMBL. 22633122

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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