Detailed information for compound 1885024

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 402.815 | Formula: C16H11ClN6O3S
  • H donors: 2 H acceptors: 4 LogP: 4.57 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)/N=N/c1c(nn(c1O)C(=S)N)c1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C16H11ClN6O3S/c17-10-3-5-11(6-4-10)19-20-14-13(21-22(15(14)24)16(18)27)9-1-7-12(8-2-9)23(25)26/h1-8,24H,(H2,18,27)/b20-19+
  • InChiKey: VTQXXHXXOWGUNC-FMQUCBEESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.032 0.0523 0.0523
Plasmodium falciparum serine repeat antigen 3 0.0637 0.1114 0.2294
Giardia lamblia Cathepsin B precursor 0.2107 0.3863 1
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0104 0.0118 0.024
Onchocerca volvulus 0.0195 0.0289 0.0595
Echinococcus multilocularis p2X purinoceptor 4 0.0711 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0637 0.1114 0.1114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Brugia malayi Calmodulin-like protein 0.0041 0.0002 0.0002
Brugia malayi programmed cell death protein 6 0.0041 0.0002 0.0002
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0185 0.0271 0.0271
Loa Loa (eye worm) ctsf protein 0.2636 0.4851 0.4851
Echinococcus granulosus EF hand domain containing family member A2 0.0041 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.1801 0.329 0.329
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0119 0.0147 0.0147
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0045 0.0009 0.0014
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0843 0.15 0.1997
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1472 0.2676 0.2674
Onchocerca volvulus 0.0637 0.1114 0.2297
Onchocerca volvulus 0.0487 0.0835 0.1721
Echinococcus granulosus growth factor receptor bound protein 2 0.0786 0.1395 0.1395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Giardia lamblia Cathepsin B precursor 0.2107 0.3863 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1472 0.2676 0.5513
Toxoplasma gondii aspartyl protease ASP3 0.0154 0.0213 0.0436
Loa Loa (eye worm) hypothetical protein 0.0048 0.0015 0.0015
Trypanosoma brucei prolyl oligopeptidase, putative 0.0054 0.0026 0.0033
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0058 0.0033 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0241 0.0375 0.077
Echinococcus multilocularis centrin 2 0.0041 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Toxoplasma gondii microneme protein MIC17A 0.01 0.0112 0.0228
Schistosoma mansoni ef hand domain family member A2 0.0041 0.0002 0.0002
Brugia malayi Pre-SET motif family protein 0.0243 0.0379 0.0379
Giardia lamblia Cathepsin L-like protease 0.0637 0.1114 0.2881
Loa Loa (eye worm) MH2 domain-containing protein 0.0217 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0056 0.003 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Echinococcus granulosus dihydrofolate reductase 0.0244 0.0381 0.0381
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0114 0.0138 0.0138
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0579 0.1006 0.1006
Brugia malayi Tyrosine-protein kinase abl-1 0.0067 0.0051 0.0051
Plasmodium vivax aspartyl protease, putative 0.0154 0.0213 0.0436
Loa Loa (eye worm) PAN domain-containing protein 0.01 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Loa Loa (eye worm) PAN domain-containing protein 0.01 0.0112 0.0112
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0041 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0089 0.0091 0.0089
Onchocerca volvulus Cathepsin L homolog 0.2636 0.4851 1
Giardia lamblia Cathepsin B precursor 0.0637 0.1114 0.2881
Giardia lamblia Cathepsin B precursor 0.2107 0.3863 1
Schistosoma mansoni hypothetical protein 0.0195 0.0289 0.0289
Echinococcus multilocularis hypothetical protein 0.0295 0.0476 0.0476
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0674 0.1185 0.3063
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0089 0.0091 0.0183
Brugia malayi Cathepsin L-like precursor 0.2636 0.4851 0.4851
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0464 0.0792 0.0792
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Trypanosoma cruzi cruzipain precursor, putative 0.4026 0.7448 0.7448
Echinococcus multilocularis cysteine protease 0.2636 0.4851 0.4851
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.032 0.0523 0.0523
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0637 0.1114 0.1114
Schistosoma mansoni egf-like domain protein 0.0116 0.0141 0.0141
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2107 0.3863 0.3862
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0009 0.0014
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0089 0.0091 0.0118
Trypanosoma cruzi conserved protein 0.0089 0.0091 0.0089
Loa Loa (eye worm) calpain family protein 1 0.0782 0.1386 0.1386
Brugia malayi Cathepsin L-like precursor 0.1801 0.329 0.329
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0637 0.1114 0.1114
Schistosoma mansoni caspase-3 (C14 family) 0.0579 0.1006 0.1006
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0241 0.0375 0.077
Echinococcus granulosus proteasome prosome macropain 0.0058 0.0033 0.0033
Echinococcus multilocularis calpain family protein 1, d 0.0576 0.1 0.1
Onchocerca volvulus 0.01 0.0112 0.0231
Brugia malayi calpain 7 0.0295 0.0476 0.0476
Trypanosoma brucei calpain-like protein, putative 0.0295 0.0476 0.0633
Echinococcus granulosus tyrosine protein kinase Fyn 0.0067 0.0051 0.0051
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0579 0.1006 0.1006
Onchocerca volvulus 0.0053 0.0025 0.0051
Onchocerca volvulus 0.1801 0.329 0.6782
Schistosoma mansoni calmodulin 0.0041 0.0002 0.0002
Brugia malayi Thioredoxin family protein 0.0107 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0698 0.1229 0.2531
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Echinococcus multilocularis p2X purinoceptor 4 0.0711 0.1253 0.1253
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1472 0.2676 0.3566
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.5392 1 1
Echinococcus multilocularis Mastin 0.032 0.0523 0.0523
Echinococcus multilocularis transmembrane protease serine 3 0.032 0.0523 0.0523
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0464 0.0792 0.1629
Echinococcus granulosus calcium uptake protein 1 0.0042 0.0002 0.0002
Echinococcus multilocularis neuronal calcium sensor 0.0041 0.0002 0.0002
Loa Loa (eye worm) calpain 0.0295 0.0476 0.0476
Brugia malayi aspartic protease BmAsp-1, identical 0.0114 0.0138 0.0138
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Schistosoma mansoni neuronal calcium sensor 0.0041 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0637 0.1114 0.2294
Trypanosoma brucei calpain, putative 0.0089 0.0091 0.0118
Schistosoma mansoni peptidylglycine monooxygenase 0.0211 0.0319 0.0319
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0674 0.1185 0.2439
Echinococcus multilocularis cysteine protease 0.2636 0.4851 0.4851
Trichomonas vaginalis set domain proteins, putative 0.0276 0.0441 0.0907
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0375 0.077
Echinococcus multilocularis caspase 2 0.0436 0.0739 0.0739
Trypanosoma brucei cysteine peptidase C (CPC) 0.2107 0.3863 0.5149
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.032 0.0523 0.0523
Schistosoma mansoni calpain-2 (C02 family) 0.0089 0.0091 0.0091
Schistosoma mansoni centrin-related 0.0041 0.0002 0.0002
Echinococcus granulosus EF HAND 1 calcium binding site 0.0041 0.0002 0.0002
Giardia lamblia Cathepsin L precursor 0.0637 0.1114 0.2881
Brugia malayi cathepsin F-like cysteine proteinase 0.0835 0.1486 0.1486
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0058 0.0033 0.0041
Entamoeba histolytica cysteine proteinase, putative 0.1472 0.2676 0.5513
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0295 0.0476 0.0474
Loa Loa (eye worm) hypothetical protein 0.0104 0.0118 0.0118
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0116 0.0141 0.0141
Echinococcus multilocularis dnaJ subfamily B 0.0338 0.0557 0.0557
Schistosoma mansoni memapsin-2 (A01 family) 0.0114 0.0138 0.0138
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0089 0.0091 0.0183
Onchocerca volvulus 0.1065 0.1916 0.3948
Toxoplasma gondii preprocathepsin c precursor, putative 0.0736 0.13 0.2676
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0089 0.0091 0.0089
Brugia malayi prolyl oligopeptidase family protein 0.0136 0.018 0.018
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0042 0.0042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0083 0.0079 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0474
Trypanosoma cruzi cysteine peptidase, putative 0.1472 0.2676 0.2674
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2636 0.4851 0.4851
Loa Loa (eye worm) hypothetical protein 0.0835 0.1486 0.1486
Toxoplasma gondii hypothetical protein 0.01 0.0112 0.0228
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0045 0.0009 0.0007
Toxoplasma gondii 1,3(4)-beta-glucanase 0.01 0.0112 0.0228
Echinococcus granulosus caspase 0.0579 0.1006 0.1006
Toxoplasma gondii kringle domain-containing protein 0.0578 0.1004 0.2067
Echinococcus granulosus neuronal calcium sensor 0.0041 0.0002 0.0002
Plasmodium vivax aspartyl protease, putative 0.0154 0.0213 0.0436
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0124 0.0961
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0599 0.1043 1
Echinococcus granulosus survival motor neuron protein 1 0.0262 0.0414 0.0414
Entamoeba histolytica cysteine protease, putative 0.2636 0.4851 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0637 0.1114 0.2294
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1472 0.2676 0.5513
Giardia lamblia Transglutaminase/protease, putative 0.0107 0.0124 0.0315
Echinococcus granulosus tyrosine protein kinase Src64B 0.0067 0.0051 0.0051
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0674 0.1185 0.2439
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0843 0.15 0.1498
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1472 0.2676 0.2676
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0295 0.0476 0.0474
Schistosoma mansoni caspase-7 (C14 family) 0.0579 0.1006 0.1006
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0104 0.0118 0.0118
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0633
Loa Loa (eye worm) papain family cysteine protease containing protein 0.2636 0.4851 0.4851
Loa Loa (eye worm) hypothetical protein 0.0067 0.0051 0.0051
Echinococcus multilocularis geminin 0.0174 0.025 0.025
Entamoeba histolytica cysteine proteinase, putative 0.2636 0.4851 1
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0843 0.15 0.3088
Loa Loa (eye worm) hypothetical protein 0.0041 0.0002 0.0002
Echinococcus granulosus Mastin 0.032 0.0523 0.0523
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0637 0.1114 0.1114
Trypanosoma cruzi metacaspase, putative 0.0241 0.0375 0.0373
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0637 0.1114 0.2294
Schistosoma mansoni hypothetical protein 0.0041 0.0002 0.0002
Plasmodium vivax plasmepsin IV, putative 0.0464 0.0792 0.1629
Plasmodium vivax unspecified product 0.0637 0.1114 0.2294
Loa Loa (eye worm) matrixin family protein 0.0054 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0637 0.1114 0.2294
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0637 0.1114 0.1114
Plasmodium vivax vivapain-2 0.2636 0.4851 1
Onchocerca volvulus 0.2636 0.4851 1
Trypanosoma cruzi oligopeptidase b 0.0054 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.1801 0.329 0.329
Brugia malayi Cathepsin L-like precursor 0.2636 0.4851 0.4851
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.3219 0.5939 0.5938
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0089 0.0091 0.0118
Echinococcus multilocularis calpain 0.0295 0.0476 0.0476
Echinococcus granulosus EF hand domain containing family member A2 0.0042 0.0002 0.0002
Echinococcus granulosus caspase 2 0.0436 0.0739 0.0739
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0637 0.1114 0.1114
Entamoeba histolytica cysteine proteinase, putative 0.1472 0.2676 0.5513
Loa Loa (eye worm) calmodulin-like protein 0.0041 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0637 0.1114 0.2294
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0243 0.0379 0.0379
Trypanosoma cruzi cruzipain precursor, putative 0.4054 0.75 0.75
Toxoplasma gondii PAN domain-containing protein 0.01 0.0112 0.0228
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0674 0.1185 0.3063
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0124 0.0961
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Toxoplasma gondii microneme protein MIC4 0.01 0.0112 0.0228
Echinococcus multilocularis calmodulin 0.0041 0.0002 0.0002
Loa Loa (eye worm) EF hand family protein 0.0041 0.0002 0.0002
Toxoplasma gondii PAN domain-containing protein 0.01 0.0112 0.0228
Loa Loa (eye worm) hypothetical protein 0.0241 0.0375 0.0375
Schistosoma mansoni reticulocalbin 0.0041 0.0002 0.0002
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Onchocerca volvulus 0.032 0.0523 0.1078
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0045 0.0009 0.0007
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0054 0.0026 0.0033
Leishmania major hypothetical protein, conserved 0.0042 0.0002 0.0001
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0633
Echinococcus granulosus calpain A 0.0295 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.2636 0.4851 0.4851
Trypanosoma brucei oligopeptidase b 0.0054 0.0026 0.0033
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0114 0.0138 0.0281
Entamoeba histolytica protein kinase, putative 0.0206 0.031 0.0636
Loa Loa (eye worm) hypothetical protein 0.01 0.0112 0.0112
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0464 0.0792 0.0792
Leishmania major cathepsin L-like protease 0.2636 0.4851 0.6468
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Entamoeba histolytica cysteine proteinase, putative 0.1801 0.329 0.6781
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0089 0.0091 0.0089
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Schistosoma mansoni calpain C (C02 family) 0.0295 0.0476 0.0476
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0633
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Loa Loa (eye worm) calpain family protein 1 0.0576 0.1 0.1
Brugia malayi calcium-binding protein 0.0041 0.0002 0.0002
Echinococcus multilocularis calpain A 0.0823 0.1463 0.1463
Echinococcus multilocularis enteropeptidase 0.032 0.0523 0.0523
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0835 0.1486 0.1486
Trypanosoma brucei Calpain-like protein 1.2 0.0089 0.0091 0.0118
Trypanosoma cruzi metacaspase 5, putative 0.0241 0.0375 0.0373
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0464 0.0792 0.0792
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1472 0.2676 0.3566
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.0021 0.0021
Schistosoma mansoni calmodulin 0.0041 0.0002 0.0002
Loa Loa (eye worm) STAT protein 0.0342 0.0564 0.0564
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0042 0.0042
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0089 0.0091 0.0089
Echinococcus multilocularis calcium uptake protein 1 0.0042 0.0002 0.0002
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0104 0.0118 0.024
Onchocerca volvulus 0.2636 0.4851 1
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.0487 0.0835 0.0835
Plasmodium vivax vivapain-3 0.1472 0.2676 0.5513
Echinococcus granulosus tyrosine protein kinase Fyn 0.0067 0.0051 0.0051
Onchocerca volvulus 0.1385 0.2514 0.5181
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0042 0.0042
Trypanosoma brucei proteasome beta 6 subunit 0.0045 0.0009 0.0009
Brugia malayi Papain family cysteine protease containing protein 0.0637 0.1114 0.1114
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0104 0.0118 0.0118
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0464 0.0792 0.0792
Echinococcus multilocularis cathepsin L cysteine protease 0.2636 0.4851 0.4851
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0295 0.0476 0.0474
Echinococcus multilocularis EF hand domain containing family member A2 0.0041 0.0002 0.0002
Giardia lamblia Cysteine protease 0.0637 0.1114 0.2881
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0089 0.0091 0.0118
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1801 0.329 0.6781
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.2107 0.3863 0.5149
Onchocerca volvulus 0.01 0.0112 0.0231
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0637 0.1114 0.1114
Toxoplasma gondii calcium binding egf domain-containing protein 0.0119 0.0147 0.03
Giardia lamblia Cysteine protease 0.0637 0.1114 0.2881
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0104 0.0118 0.024
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0088 0.009 0.009
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0241 0.0375 0.077
Toxoplasma gondii PAN domain-containing protein 0.01 0.0112 0.0228
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0051 0.0051
Echinococcus multilocularis caspase 8 0.0241 0.0375 0.0375
Echinococcus multilocularis caspase 3 0.0338 0.0556 0.0556
Schistosoma mansoni tyrosine kinase 0.0067 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0067 0.0051 0.0051
Loa Loa (eye worm) programmed cell death protein 6 0.0042 0.0002 0.0002
Schistosoma mansoni survival motor neuron protein 0.0053 0.0025 0.0025
Leishmania major cathepsin L-like protease 0.2636 0.4851 0.6468
Onchocerca volvulus Cathepsin L homolog 0.0637 0.1114 0.2297
Loa Loa (eye worm) hypothetical protein 0.032 0.0523 0.0523
Plasmodium falciparum calpain 0.0089 0.0091 0.0183
Schistosoma mansoni calpain-7 (C02 family) 0.0295 0.0476 0.0476
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0077 0.0068 0.0137
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Echinococcus multilocularis cathepsin b 0.5392 1 1
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0045 0.0009 0.0014
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Echinococcus multilocularis tissue type plasminogen activator 0.0578 0.1004 0.1004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0797 0.1415 0.2914
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Schistosoma mansoni Mername-AA248 (C02 family) 0.0295 0.0476 0.0476
Entamoeba histolytica cysteine proteinase, putative 0.1472 0.2676 0.5513
Brugia malayi Cathepsin L-like cysteine proteinase 0.1801 0.329 0.329
Loa Loa (eye worm) hypothetical protein 0.0262 0.0414 0.0414
Echinococcus granulosus cathepsin l1 0.2636 0.4851 0.4851
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0285 0.0457 0.0455
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0295 0.0476 0.0633
Trypanosoma cruzi kinesin, putative 0.0206 0.031 0.0309
Trypanosoma cruzi cysteine peptidase, putative 0.4054 0.75 0.75
Loa Loa (eye worm) SRC-1 0.0067 0.0051 0.0051
Schistosoma mansoni growth factor receptor-bound protein 0.0786 0.1395 0.1395
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.032 0.0523 0.0523
Brugia malayi Fibulin-1 precursor 0.0119 0.0147 0.0147
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0104 0.0118 0.0118
Trichomonas vaginalis calpain, putative 0.0089 0.0091 0.0183
Brugia malayi Papain family cysteine protease containing protein 0.1472 0.2676 0.2676
Loa Loa (eye worm) hypothetical protein 0.5392 1 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0736 0.13 0.2676
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2636 0.4851 1
Brugia malayi cathepsin L precursor 0.0637 0.1114 0.1114
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0823 0.1463 0.1463
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0041 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0136 0.018 0.018
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0058 0.0033 0.0062
Onchocerca volvulus 0.0276 0.0441 0.091
Plasmodium falciparum proteasome subunit beta type-5 0.0058 0.0033 0.0063
Mycobacterium ulcerans transglutaminase family protein 0.0107 0.0124 0.0961
Onchocerca volvulus Neurogenic locus notch protein homolog 0.004 0.0000000027214 0.0000000056094
Brugia malayi hypothetical protein 0.032 0.0523 0.0523
Echinococcus multilocularis programmed cell death protein 0.0041 0.0002 0.0002
Onchocerca volvulus 0.01 0.0112 0.0231
Plasmodium falciparum serine repeat antigen 4 0.0637 0.1114 0.2294
Toxoplasma gondii cathepsin CPC2 0.0674 0.1185 0.2439
Plasmodium falciparum cysteine proteinase falcipain 3 0.2636 0.4851 1
Toxoplasma gondii PAN/Apple domain-containing protein 0.01 0.0112 0.0228
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0736 0.13 0.2676
Plasmodium vivax plasmepsin V, putative 0.0114 0.0138 0.0281
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1472 0.2676 0.2676
Brugia malayi calpain 5 0.0206 0.031 0.031
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Loa Loa (eye worm) hypothetical protein 0.0119 0.0147 0.0147
Brugia malayi Calcium binding EGF domain containing protein 0.0119 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Mycobacterium tuberculosis Possible exported protein 0.0354 0.0587 0.551
Echinococcus granulosus cathepsin L cysteine proteinase 0.2636 0.4851 0.4851
Entamoeba histolytica grainin, putative 0.0042 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Plasmodium falciparum cysteine proteinase falcipain 2a 0.2636 0.4851 1
Plasmodium vivax aspartyl proteinase, putative 0.0464 0.0792 0.1629
Schistosoma mansoni neuronal calcium sensor 0.0041 0.0002 0.0002
Trypanosoma cruzi cysteine proteinase, putative 0.1472 0.2676 0.2674
Plasmodium falciparum plasmepsin X 0.0154 0.0213 0.0436
Onchocerca volvulus 0.0042 0.0002 0.0005
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Trichomonas vaginalis peptide N-glycanase, putative 0.0107 0.0124 0.0252
Brugia malayi EF hand family protein 0.0042 0.0002 0.0002
Echinococcus granulosus neurocalcin 0.0041 0.0002 0.0002
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0045 0.0009 0.0009
Plasmodium falciparum plasmepsin VIII, putative 0.0114 0.0138 0.0281
Loa Loa (eye worm) hypothetical protein 0.0114 0.0138 0.0138
Onchocerca volvulus 0.2636 0.4851 1
Echinococcus granulosus calpain 0.0295 0.0476 0.0476
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0067 0.0051 0.0051
Brugia malayi Sex muscle abnormal protein 5 0.0786 0.1395 0.1395
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.032 0.0523 0.0523
Echinococcus multilocularis calbindin 32 0.0042 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.01 0.0112 0.0112
Echinococcus granulosus Transglutaminase 0.0107 0.0124 0.0124
Onchocerca volvulus 0.032 0.0523 0.1078
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0067 0.0051 0.0051
Onchocerca volvulus Matrix metalloproteinase homolog 0.0054 0.0025 0.0052
Trypanosoma brucei metacaspase MCA2 0.0241 0.0375 0.0498
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0045 0.0009 0.0014
Trypanosoma cruzi oligopeptidase b 0.0054 0.0026 0.0025
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0054 0.0026 0.0025
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0088 0.009 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0089 0.0091 0.0089
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0116 0.0141 0.0141
Schistosoma mansoni calpain-7 (C02 family) 0.0295 0.0476 0.0476
Loa Loa (eye worm) TK/ROR protein kinase 0.0578 0.1004 0.1004
Echinococcus granulosus p2X purinoceptor 4 0.0711 0.1253 0.1253
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Echinococcus multilocularis calmodulin 0.0041 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0174 0.025 0.025
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Onchocerca volvulus 0.2636 0.4851 1
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.032 0.0523 0.0523
Schistosoma mansoni cathepsin F (C01 family) 0.2636 0.4851 0.4851
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0375 0.077
Schistosoma mansoni hypothetical protein 0.0056 0.003 0.003
Leishmania major cathepsin L-like protease 0.2636 0.4851 0.6468
Loa Loa (eye worm) hypothetical protein 0.0637 0.1114 0.1114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Trypanosoma brucei calpain-like protein, putative 0.0295 0.0476 0.0633
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0599 0.1043 0.1043
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0244 0.0381 0.3488
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0637 0.1114 0.2294
Echinococcus multilocularis neurocalcin 0.0041 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Brugia malayi Angiotensin-converting enzyme family protein 0.0426 0.0721 0.0721
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0426 0.0721 0.0721
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Plasmodium falciparum serine repeat antigen 9 0.0637 0.1114 0.2294
Echinococcus multilocularis thymidylate synthase 0.0599 0.1043 0.1043
Trypanosoma cruzi cysteine peptidase, putative 0.4026 0.7448 0.7448
Loa Loa (eye worm) hypothetical protein 0.0637 0.1114 0.1114
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0067 0.0051 0.0051
Brugia malayi cathepsin Z-like cysteine proteinase 0.0797 0.1415 0.1415
Echinococcus multilocularis cathepsin b 0.5392 1 1
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0397 0.0666 0.0666
Onchocerca volvulus 0.032 0.0523 0.1078
Loa Loa (eye worm) hypothetical protein 0.0835 0.1486 0.1486
Loa Loa (eye worm) thymidylate synthase 0.0599 0.1043 0.1043
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0244 0.0381 0.3488
Echinococcus granulosus cathepsin b 0.5392 1 1
Trypanosoma brucei antigen, putative 0.0295 0.0476 0.0633
Trypanosoma cruzi metacaspase 5, putative 0.0241 0.0375 0.0373
Brugia malayi latrophilin 2 splice variant baaae 0.0056 0.003 0.003
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0637 0.1114 0.2294
Loa Loa (eye worm) proteasome subunit beta type 1 0.0045 0.0009 0.0009
Echinococcus multilocularis cathepsin L 0.1472 0.2676 0.2676
Mycobacterium ulcerans hypothetical protein 0.0107 0.0124 0.0961
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0749 0.1325 0.1325
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0067 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1801 0.329 0.6781
Brugia malayi Matrixin family protein 0.0059 0.0034 0.0034
Trypanosoma cruzi metacaspase, putative 0.0241 0.0375 0.0373
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0042 0.0002 0.0001
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0637 0.1114 0.2294
Loa Loa (eye worm) hypothetical protein 0.0576 0.1 0.1
Brugia malayi cathepsin F-like cysteine proteinase 0.0637 0.1114 0.1114
Schistosoma mansoni growth factor receptor-bound protein 0.0786 0.1395 0.1395
Loa Loa (eye worm) RNA binding protein 0.0063 0.0042 0.0042
Schistosoma mansoni reticulocalbin 0.0042 0.0002 0.0002
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0122 0.0153 0.1246
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Brugia malayi TAR-binding protein 0.0063 0.0042 0.0042
Schistosoma mansoni P2X receptor subunit 0.0711 0.1253 0.1253
Brugia malayi fibroinase precursor 0.0637 0.1114 0.1114
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.5392 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2636 0.4851 1
Onchocerca volvulus 0.01 0.0112 0.0231
Plasmodium falciparum metacaspase 1 0.0241 0.0375 0.077
Mycobacterium tuberculosis Conserved protein 0.0107 0.0124 0.0961
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0637 0.1114 0.2294
Giardia lamblia Cathepsin B precursor 0.0637 0.1114 0.2881
Onchocerca volvulus 0.0107 0.0124 0.0255
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0397 0.0666 0.0666
Echinococcus multilocularis prolyl endopeptidase 0.0136 0.018 0.018
Plasmodium falciparum plasmepsin VII 0.0114 0.0138 0.0281
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0104 0.0118 0.024
Loa Loa (eye worm) hypothetical protein 0.032 0.0523 0.0523
Trypanosoma cruzi metacaspase, putative 0.0241 0.0375 0.0373
Loa Loa (eye worm) hypothetical protein 0.0041 0.0002 0.0002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Brugia malayi Cathepsin L-like precursor 0.0835 0.1486 0.1486
Schistosoma mansoni neuronal calcium sensor 0.0041 0.0002 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0637 0.1114 0.1114
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0843 0.15 0.1997
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0797 0.1415 0.2914
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0083 0.0079 0.0079
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0089 0.0091 0.0183
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0104 0.0118 0.024
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1385 0.2514 0.2514
Brugia malayi Papain family cysteine protease containing protein 0.1472 0.2676 0.2676
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0637 0.1114 0.1114
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0058 0.0033 0.0031
Schistosoma mansoni hypothetical protein 0.0041 0.0002 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.0708 0.1247 0.1247
Onchocerca volvulus 0.01 0.0112 0.0231
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0185 0.0271 0.0271
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Brugia malayi cathepsin Z-like cysteine proteinase 0.0797 0.1415 0.1415
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Entamoeba histolytica calpain large subunit domain III containing protein 0.0206 0.031 0.0636
Trypanosoma cruzi hypothetical protein, conserved 0.0578 0.1004 0.1002
Plasmodium falciparum cysteine repeat modular protein 1 0.0578 0.1004 0.2067
Echinococcus granulosus thymidylate synthase 0.0599 0.1043 0.1043
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0067 0.0051 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0042 0.0042
Echinococcus granulosus c src tyrosine kinase 0.0067 0.0051 0.0051
Echinococcus granulosus laminin 0.0119 0.0147 0.0147
Schistosoma mansoni tyrosine kinase 0.0067 0.0051 0.0051
Chlamydia trachomatis dihydrofolate reductase 0.0244 0.0381 0.5
Echinococcus granulosus apoptotic protease activating factor 1 0.0195 0.0289 0.0289
Plasmodium vivax proteasome subunit beta type-1, putative 0.0045 0.0009 0.0014
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0067 0.0051 0.0051
Plasmodium vivax serine-repeat antigen (SERA) 0.0637 0.1114 0.2294
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0136 0.018 0.018
Toxoplasma gondii hypothetical protein 0.01 0.0112 0.0228
Echinococcus granulosus NCK adaptor protein 0.0067 0.0051 0.0051
Brugia malayi Pepsin A precursor 0.0114 0.0138 0.0138
Toxoplasma gondii cathepsin CPL 0.2636 0.4851 1
Leishmania major metacaspase, putative 0.0241 0.0375 0.0498
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0042 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase Src42A 0.0067 0.0051 0.0051
Echinococcus multilocularis tyrosine protein kinase Abl 0.0067 0.0051 0.0051
Plasmodium vivax unspecified product 0.0835 0.1486 0.3061
Trypanosoma brucei Calpain-like protein 1.1 0.0089 0.0091 0.0118
Onchocerca volvulus 0.01 0.0112 0.0231
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0089 0.0091 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Schistosoma mansoni calpain (C02 family) 0.0295 0.0476 0.0476
Onchocerca volvulus 0.0041 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.1801 0.329 0.329
Giardia lamblia Cathepsin L precursor 0.0637 0.1114 0.2881
Echinococcus granulosus glycoprotein Antigen 5 0.032 0.0523 0.0523
Schistosoma mansoni P2X receptor subunit 0.0711 0.1253 0.1253
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Toxoplasma gondii cathepsin B 0.2107 0.3863 0.7961
Schistosoma mansoni cathepsin D (A01 family) 0.1404 0.2548 0.2548
Toxoplasma gondii calcium-dependent protein kinase 0.0042 0.0002 0.0002
Echinococcus granulosus transmembrane protease serine 3 0.032 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.032 0.0523 0.0523
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2636 0.4851 0.4851
Schistosoma mansoni neuronal calcium sensor 0.0041 0.0002 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Plasmodium vivax unspecified product 0.1472 0.2676 0.5513
Toxoplasma gondii prolyl endopeptidase 0.0136 0.018 0.0367
Entamoeba histolytica cysteine protease, putative 0.0637 0.1114 0.2294
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Trichomonas vaginalis calpain, putative 0.0089 0.0091 0.0183
Loa Loa (eye worm) hypothetical protein 0.01 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0089 0.0091 0.0183
Loa Loa (eye worm) calpain 5 0.0206 0.031 0.031
Plasmodium falciparum plasmepsin II 0.0464 0.0792 0.1629
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0025 0.0025
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Brugia malayi hypothetical protein 0.0195 0.0289 0.0289
Echinococcus granulosus caspase 3 0.0338 0.0556 0.0556
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0375 0.077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Giardia lamblia Cathepsin L precursor 0.0637 0.1114 0.2881
Giardia lamblia Hypothetical protein 0.0637 0.1114 0.2881
Echinococcus granulosus p2X purinoceptor 4 0.0711 0.1253 0.1253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0637 0.1114 0.2294
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0067 0.0051 0.0051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Toxoplasma gondii PAN domain-containing protein 0.01 0.0112 0.0228
Loa Loa (eye worm) hypothetical protein 0.0578 0.1004 0.1004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0083 0.0079 0.0079
Echinococcus multilocularis p2X purinoceptor 4 0.0711 0.1253 0.1253
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0474
Echinococcus multilocularis cathepsin L 0.0637 0.1114 0.1114
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0599 0.1043 1
Entamoeba histolytica cysteine proteinase 2 0.1472 0.2676 0.5513
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0058 0.0033 0.0063
Brugia malayi Eukaryotic aspartyl protease family protein 0.0114 0.0138 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0067 0.0051 0.0051
Onchocerca volvulus 0.0114 0.0138 0.0284
Brugia malayi dihydrofolate reductase family protein 0.0244 0.0381 0.0381
Entamoeba histolytica cysteine protease, putative 0.0637 0.1114 0.2294
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0736 0.13 0.336
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0042 0.0042
Plasmodium vivax serine-repeat antigen (SERA) 0.0637 0.1114 0.2294
Schistosoma mansoni cathepsin S (C01 family) 0.0637 0.1114 0.1114
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0843 0.15 0.3088
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.032 0.0523 0.0523
Trypanosoma cruzi cysteine peptidase, putative 0.4054 0.75 0.75
Echinococcus multilocularis Tolloid protein 1 0.0185 0.0271 0.0271
Brugia malayi hypothetical protein 0.0114 0.0138 0.0138
Trichomonas vaginalis calpain, putative 0.0089 0.0091 0.0183
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Toxoplasma gondii calcium binding egf domain-containing protein 0.0119 0.0147 0.03
Brugia malayi Cathepsin L-like precursor 0.2636 0.4851 0.4851
Leishmania major cathepsin L-like protease 0.4054 0.75 1
Loa Loa (eye worm) hypothetical protein 0.0637 0.1114 0.1114
Trypanosoma brucei Calpain-like protein 2 0.0089 0.0091 0.0118
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0045 0.0009 0.0009
Toxoplasma gondii proteasome subunit beta type, putative 0.0058 0.0033 0.0063
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Giardia lamblia Cathepsin B precursor 0.0637 0.1114 0.2881
Brugia malayi Papain family cysteine protease containing protein 0.2636 0.4851 0.4851
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Echinococcus granulosus tyrosine protein kinase Lyn 0.0067 0.0051 0.0051
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0736 0.13 0.2676
Brugia malayi Trypsin family protein 0.032 0.0523 0.0523
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5392 1 1
Toxoplasma gondii hypothetical protein 0.0089 0.0091 0.0183
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0637 0.1114 0.2294
Plasmodium falciparum serine repeat antigen 7 0.0637 0.1114 0.2294
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0083 0.0079 0.0079
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0782 0.1386 0.1386
Mycobacterium leprae Conserved hypothetical protein 0.0107 0.0124 0.0961
Loa Loa (eye worm) hypothetical protein 0.1385 0.2514 0.2514
Loa Loa (eye worm) hypothetical protein 0.0782 0.1386 0.1386
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0045 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0637 0.1114 0.2294
Onchocerca volvulus Putative cubilin 0.0048 0.0015 0.0032
Onchocerca volvulus 0.01 0.0112 0.0231
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.032 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.0464 0.0792 0.0792
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0083 0.0079 0.0079
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0067 0.0051 0.0051
Plasmodium falciparum plasmepsin IV 0.0464 0.0792 0.1629
Onchocerca volvulus Neurogenic locus notch homolog 0.004 0.0000000027214 0.0000000056094
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0241 0.0375 0.077
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.01 0.0112 0.0112
Toxoplasma gondii aspartyl protease ASP1 0.0464 0.0792 0.1629
Leishmania major cathepsin L-like protease 0.2636 0.4851 0.6468
Toxoplasma gondii hypothetical protein 0.0077 0.0068 0.0137
Echinococcus granulosus calmodulin 0.0041 0.0002 0.0002
Plasmodium vivax vivapain-1 0.1472 0.2676 0.5513
Loa Loa (eye worm) hypothetical protein 0.0127 0.0163 0.0163
Trypanosoma cruzi cysteine peptidase, putative 0.2636 0.4851 0.4851
Toxoplasma gondii calmodulin CAM1 0.0042 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0083 0.0079 0.0079
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0082 0.0079 0.0079
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0067 0.0051 0.0051
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0053 0.0025 0.0025
Schistosoma mansoni cathepsin F (C01 family) 0.2636 0.4851 0.4851
Giardia lamblia Cathepsin B precursor 0.0797 0.1415 0.3659
Echinococcus granulosus cathepsin l1 0.1801 0.329 0.329
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0058 0.0033 0.0031
Plasmodium falciparum plasmepsin III 0.0114 0.0138 0.0281
Loa Loa (eye worm) hypothetical protein 0.0835 0.1486 0.1486
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0637 0.1114 0.2294
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Brugia malayi Trypsin family protein 0.032 0.0523 0.0523
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0067 0.0051 0.0051
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Loa Loa (eye worm) hypothetical protein 0.1801 0.329 0.329
Loa Loa (eye worm) hypothetical protein 0.0397 0.0666 0.0666
Brugia malayi MH2 domain containing protein 0.0217 0.033 0.033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0633
Plasmodium falciparum cysteine proteinase falcipain 1 0.1472 0.2676 0.5513
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Schistosoma mansoni cathepsin C 0.0637 0.1114 0.1114
Loa Loa (eye worm) PAN domain-containing protein 0.01 0.0112 0.0112
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0375 0.077
Echinococcus multilocularis programmed cell death protein 0.0041 0.0002 0.0002
Brugia malayi Calcium binding EGF domain containing protein 0.0048 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.032 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.01 0.0112 0.0112
Giardia lamblia Cathepsin L precursor 0.0637 0.1114 0.2881
Plasmodium vivax calpain, putative 0.0295 0.0476 0.0978
Echinococcus granulosus enteropeptidase 0.032 0.0523 0.0523
Onchocerca volvulus 0.01 0.0112 0.0231
Echinococcus multilocularis NCK adaptor protein 0.0067 0.0051 0.0051
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0045 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0637 0.1114 0.2294
Brugia malayi hypothetical protein 0.0285 0.0457 0.0457
Schistosoma mansoni centrin 0.0041 0.0002 0.0002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Toxoplasma gondii cathepsin CPC1 0.0736 0.13 0.2676
Loa Loa (eye worm) PAN domain-containing protein 0.01 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0637 0.1114 0.2294
Echinococcus granulosus dnaJ subfamily B 0.0338 0.0557 0.0557
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0136 0.018 0.0237
Mycobacterium ulcerans putative transglutaminase-like protein 0.0107 0.0124 0.0961
Loa Loa (eye worm) fibroinase 0.2636 0.4851 0.4851
Brugia malayi proteasome subunit beta type 1 0.0045 0.0009 0.0009
Onchocerca volvulus Cell death protein 3 homolog 0.0436 0.0739 0.1523
Leishmania major cysteine peptidase A (CPA) 0.2636 0.4851 0.6468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Echinococcus granulosus calpain 5 0.0295 0.0476 0.0476
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0578 0.1004 0.2067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0637 0.1114 0.2294
Giardia lamblia Cathepsin B precursor 0.0637 0.1114 0.2881
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.2107 0.3863 0.7961
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0397 0.0666 0.0666
Echinococcus granulosus calumenin 0.0042 0.0002 0.0002
Echinococcus granulosus centrin 2 0.0041 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0375 0.077
Leishmania major hypothetical protein, conserved 0.0578 0.1004 0.1337
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0058 0.0033 0.0078
Echinococcus multilocularis fibrillin 1 0.0119 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0116 0.0141 0.0141
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5392 1 1
Entamoeba histolytica cysteine proteinase 1, putative 0.1472 0.2676 0.5513
Loa Loa (eye worm) hypothetical protein 0.0637 0.1114 0.1114
Onchocerca volvulus 0.0041 0.0002 0.0004
Schistosoma mansoni cathepsin s 0.0835 0.1486 0.1486
Schistosoma mansoni hypothetical protein 0.0089 0.0091 0.0091
Echinococcus multilocularis calpain 5 0.0295 0.0476 0.0476
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0067 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.032 0.0523 0.0523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Onchocerca volvulus 0.01 0.0112 0.0231
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0637 0.1114 0.1114
Echinococcus multilocularis laminin 0.0119 0.0147 0.0147
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0823 0.1463 0.1463
Mycobacterium ulcerans hypothetical protein 0.0107 0.0124 0.0961
Schistosoma mansoni nck2/grb4 0.0067 0.0051 0.0051
Giardia lamblia Rab geranylgeranyltransferase 0.0104 0.0118 0.03
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0823 0.1463 0.1463
Plasmodium falciparum plasmepsin VI 0.0464 0.0792 0.1629
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0637 0.1114 0.2881
Leishmania major cathepsin L-like protease 0.4054 0.75 1
Trypanosoma brucei calpain, putative 0.0089 0.0091 0.0118
Onchocerca volvulus Cathepsin L homolog 0.2636 0.4851 1
Echinococcus granulosus calbindin 32 0.0042 0.0002 0.0002
Echinococcus multilocularis calumenin 0.0042 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0285 0.0457 0.0939
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0089 0.0091 0.0089
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0835 0.1486 0.1486
Trypanosoma cruzi cysteine proteinase, putative 0.1472 0.2676 0.2674
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0797 0.1415 0.2914
Echinococcus granulosus calpain A 0.0823 0.1463 0.1463
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0054 0.0026 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0637 0.1114 0.2294
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0042 0.0042
Toxoplasma gondii aspartyl protease 0.0114 0.0138 0.0281
Leishmania major proteasome beta 5 subunit, putative 0.0058 0.0033 0.0041
Giardia lamblia Hypothetical protein 0.0107 0.0124 0.0315
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Echinococcus granulosus tachykinin peptides receptor 99D 0.2058 0.3771 0.3771
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0051 0.0051
Plasmodium falciparum plasmepsin I 0.0464 0.0792 0.1629
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0637 0.1114 0.2294
Trypanosoma brucei calmodulin, putative 0.0042 0.0002 0.0001
Trypanosoma brucei Metacaspase-4 0.0241 0.0375 0.0498
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2107 0.3863 0.3863
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0736 0.13 0.13
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1394 0.2529 0.2529
Loa Loa (eye worm) hypothetical protein 0.0114 0.0138 0.0138
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0474
Loa Loa (eye worm) cathepsin B 0.2107 0.3863 0.3863
Loa Loa (eye worm) hypothetical protein 0.0089 0.0091 0.0091
Trypanosoma cruzi kinesin, putative 0.0206 0.031 0.0309
Schistosoma mansoni caspase-7 (C14 family) 0.0436 0.0739 0.0739
Loa Loa (eye worm) hypothetical protein 0.0436 0.0739 0.0739
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0295 0.0476 0.0474
Brugia malayi Trypsin-like protease protein 5 0.032 0.0523 0.0523
Giardia lamblia Cysteine protease 0.0637 0.1114 0.2881
Echinococcus granulosus programmed cell death protein 0.0041 0.0002 0.0002
Leishmania major oligopeptidase b 0.0054 0.0026 0.0033
Plasmodium falciparum metacaspase-like protein 0.0241 0.0375 0.077
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0054 0.0026 0.0025
Entamoeba histolytica cysteine proteinase, putative 0.1472 0.2676 0.5513
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Schistosoma mansoni hypothetical protein 0.0174 0.025 0.025
Trypanosoma cruzi cysteine protease, putative 0.1472 0.2676 0.2674
Loa Loa (eye worm) dihydrofolate reductase 0.0244 0.0381 0.0381
Plasmodium falciparum serine repeat antigen 5 0.0637 0.1114 0.2294
Mycobacterium tuberculosis Hypothetical protein 0.0285 0.0457 0.4235
Schistosoma mansoni microtubule-associated protein tau 0.0708 0.1247 0.1247
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0067 0.0051 0.0051
Echinococcus multilocularis glycoprotein Antigen 5 0.032 0.0523 0.0523
Brugia malayi RNA binding protein 0.0063 0.0042 0.0042
Echinococcus granulosus microtubule associated protein 2 0.0708 0.1247 0.1247
Loa Loa (eye worm) hypothetical protein 0.0693 0.122 0.122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Mycobacterium ulcerans hypothetical protein 0.032 0.0523 0.4882
Schistosoma mansoni rab 0.0041 0.0002 0.0002
Brugia malayi Cell death protein 3 precursor 0.0436 0.0739 0.0739
Brugia malayi Trypsin family protein 0.1385 0.2514 0.2514
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0058 0.0033 0.0033
Giardia lamblia Cathepsin L precursor 0.0637 0.1114 0.2881
Trypanosoma brucei metacaspase 5, putative 0.0241 0.0375 0.0498
Mycobacterium tuberculosis Hypothetical protein 0.0107 0.0124 0.0961
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0295 0.0476 0.0474
Echinococcus granulosus cathepsin L cysteine protease 0.1472 0.2676 0.2676
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0464 0.0792 0.1629
Leishmania major hypothetical protein, unknown function 0.0089 0.0091 0.0118
Schistosoma mansoni hypothetical protein 0.0338 0.0557 0.0557
Brugia malayi Trypsin family protein 0.032 0.0523 0.0523
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0637 0.1114 0.2294
Trypanosoma brucei kinesin, putative 0.0206 0.031 0.0412
Loa Loa (eye worm) hypothetical protein 0.01 0.0112 0.0112
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0083 0.0079 0.0079
Onchocerca volvulus 0.0578 0.1004 0.207
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0067 0.0051 0.0051
Echinococcus multilocularis Transglutaminase 0.0107 0.0124 0.0124
Schistosoma mansoni mitochondrial solute carrier 0.0041 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0089 0.0091 0.0183
Mycobacterium ulcerans thymidylate synthase 0.0599 0.1043 1
Plasmodium vivax proteasome subunit beta type-5, putative 0.0058 0.0033 0.0063
Loa Loa (eye worm) hypothetical protein 0.0195 0.0289 0.0289
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0083 0.0079 0.0079
Echinococcus multilocularis caspase 0.0579 0.1006 0.1006
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0637 0.1114 0.2294
Plasmodium falciparum serine repeat antigen 8 0.0637 0.1114 0.2294
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0823 0.1463 0.1463
Trichomonas vaginalis calmodulin, putative 0.0042 0.0002 0.0002
Plasmodium falciparum serine repeat antigen 6 0.0637 0.1114 0.2294
Plasmodium vivax vivapain-2 0.2636 0.4851 1
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0058 0.0033 0.0033
Toxoplasma gondii microneme protein MIC17C 0.01 0.0112 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Plasmodium vivax aspartyl proteinase, putative 0.0114 0.0138 0.0281
Schistosoma mansoni calmodulin related calcium binding protein 0.0041 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0797 0.1415 0.2914
Toxoplasma gondii histone lysine methyltransferase SET1 0.0046 0.0011 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Onchocerca volvulus 0.0114 0.0138 0.0284
Trichomonas vaginalis hypothetical protein 0.0089 0.0091 0.0183
Loa Loa (eye worm) PAN domain-containing protein 0.01 0.0112 0.0112
Echinococcus granulosus cathepsin L 0.1472 0.2676 0.2676
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Trypanosoma brucei calpain-like protein, putative 0.0295 0.0476 0.0633
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0843 0.15 0.3088
Loa Loa (eye worm) calpain D 0.0089 0.0091 0.0091
Onchocerca volvulus 0.2636 0.4851 1
Brugia malayi calpain D 0.0089 0.0091 0.0091
Entamoeba histolytica cysteine protease, putative 0.1472 0.2676 0.5513
Trypanosoma brucei metacaspase 0.0241 0.0375 0.0498
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0002 0.0002
Onchocerca volvulus 0.2636 0.4851 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Schistosoma mansoni dopamine-beta-monooxygenase 0.0211 0.0319 0.0319
Onchocerca volvulus 0.032 0.0523 0.1078
Toxoplasma gondii PAN domain-containing protein 0.01 0.0112 0.0228
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0295 0.0476 0.0474
Brugia malayi Kringle domain containing protein 0.0578 0.1004 0.1004
Onchocerca volvulus Prolyl endopeptidase homolog 0.0136 0.018 0.037
Brugia malayi Protein kinase domain containing protein 0.0578 0.1004 0.1004
Echinococcus granulosus caspase 8 0.0241 0.0375 0.0375
Echinococcus multilocularis calpain 7 (C02 family) 0.0295 0.0476 0.0476
Onchocerca volvulus Cathepsin F homolog 0.2636 0.4851 1
Onchocerca volvulus 0.01 0.0112 0.0231
Brugia malayi cathepsin L-like precursor 0.1801 0.329 0.329
Trichomonas vaginalis conserved hypothetical protein 0.0637 0.1114 0.2294
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0058 0.0033 0.0062
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0328 0.0538 0.0538
Brugia malayi hypothetical protein 0.0114 0.0138 0.0138
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0637 0.1114 0.1114
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.032 0.0523 0.0523
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Brugia malayi Cathepsin L-like precursor 0.2636 0.4851 0.4851
Schistosoma mansoni P2X receptor subunit 0.0711 0.1253 0.1253
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0637 0.1114 0.2294
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0211 0.0319 0.0319
Toxoplasma gondii subtilisin SUB12 0.01 0.0112 0.0228
Echinococcus multilocularis dihydrofolate reductase 0.0244 0.0381 0.0381
Schistosoma mansoni cathepsin F (C01 family) 0.1801 0.329 0.329
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0104 0.0118 0.0118
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0089
Echinococcus multilocularis c src tyrosine kinase 0.0067 0.0051 0.0051
Brugia malayi Cathepsin L-like precursor 0.2636 0.4851 0.4851
Brugia malayi Dihydrofolate reductase 0.0244 0.0381 0.0381
Loa Loa (eye worm) trypsin family protein 0.032 0.0523 0.0523
Brugia malayi cathepsin L-like cysteine proteinase 0.0637 0.1114 0.1114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5392 1 1
Leishmania major calpain protease-like protein 0.0089 0.0091 0.0118
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.2636 0.4851 0.4851
Giardia lamblia Cathepsin L precursor 0.0637 0.1114 0.2881
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0104 0.0119 0.0119
Brugia malayi calpain family protein 1 0.0782 0.1386 0.1386
Loa Loa (eye worm) AStacin protease 0.0061 0.0039 0.0039
Echinococcus granulosus prolyl endopeptidase 0.0136 0.018 0.018
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0089 0.0091 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2636 0.4851 1
Leishmania major hypothetical protein, conserved 0.0089 0.0091 0.0118
Loa Loa (eye worm) matrixin family protein 0.0059 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase, putative 0.4054 0.75 0.75
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0041 0.0002 0.0002
Echinococcus granulosus tar DNA binding protein 0.0063 0.0042 0.0042
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1472 0.2676 0.2676
Entamoeba histolytica cysteine protease, putative 0.0637 0.1114 0.2294
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0375 0.077
Leishmania major cathepsin L-like protease 0.4054 0.75 1
Entamoeba histolytica cysteine protease, putative 0.0637 0.1114 0.2294
Trypanosoma cruzi prolyl endopeptidase 0.0136 0.018 0.0178
Schistosoma mansoni P2X receptor subunit 0.0711 0.1253 0.1253
Brugia malayi hypothetical protein 0.0262 0.0414 0.0414
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Echinococcus multilocularis cathepsin L cysteine protease 0.2636 0.4851 0.4851
Brugia malayi Papain family cysteine protease containing protein 0.0637 0.1114 0.1114
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0295 0.0476 0.0474
Entamoeba histolytica calpain family cysteine protease, putative 0.0089 0.0091 0.0183
Echinococcus granulosus tissue type plasminogen activator 0.0578 0.1004 0.1004
Leishmania major cathepsin L-like protease 0.2636 0.4851 0.6468
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0082 0.0079 0.0079
Brugia malayi STAT protein, DNA binding domain containing protein 0.0342 0.0564 0.0564
Schistosoma mansoni adapter molecule crk 0.0067 0.0051 0.0051
Entamoeba histolytica cysteine protease, putative 0.0637 0.1114 0.2294
Leishmania major kinesin, putative 0.0206 0.031 0.0412
Echinococcus granulosus calpain 7 C02 family 0.0295 0.0476 0.0476
Brugia malayi Cathepsin L-like precursor 0.2636 0.4851 0.4851
Loa Loa (eye worm) hypothetical protein 0.0637 0.1114 0.1114
Onchocerca volvulus Matrilysin homolog 0.0054 0.0025 0.0052
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0083 0.0079 0.0079
Plasmodium falciparum plasmepsin IX 0.0154 0.0213 0.0436
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0637 0.1114 0.2294
Toxoplasma gondii PAN domain-containing protein 0.01 0.0112 0.0228
Onchocerca volvulus 0.2636 0.4851 1
Trypanosoma brucei calpain-like protein, putative 0.0295 0.0476 0.0633
Echinococcus granulosus cathepsin b 0.5392 1 1
Giardia lamblia Cysteine protease 0.0637 0.1114 0.2881
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0107 0.0125 0.0125
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0637 0.1114 0.1114
Echinococcus granulosus p2X purinoceptor 4 0.0711 0.1253 0.1253
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0091 0.0183
Schistosoma mansoni hypothetical protein 0.0107 0.0124 0.0124
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0089 0.0091 0.0089
Entamoeba histolytica cysteine proteinase, putative 0.2636 0.4851 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0637 0.1114 0.1114
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0067 0.0051 0.0051
Echinococcus granulosus cathepsin L 0.0637 0.1114 0.1114
Schistosoma mansoni cathepsin B (C01 family) 0.0637 0.1114 0.1114
Echinococcus granulosus cathepsin l cysteine peptidase 0.2636 0.4851 0.4851
Plasmodium vivax aspartyl protease, putative 0.0114 0.0138 0.0281
Mycobacterium ulcerans proteasome PrcB 0.0058 0.0033 0.0062
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0104 0.0118 0.024
Giardia lamblia Hypothetical protein 0.0637 0.1114 0.2881
Echinococcus granulosus Tolloid protein 1 0.0185 0.0271 0.0271
Plasmodium falciparum serine repeat antigen 2 0.0637 0.1114 0.2294
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0241 0.0375 0.0375
Echinococcus multilocularis proteasome (prosome, macropain) 0.0058 0.0033 0.0033
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0241 0.0375 0.077
Mycobacterium leprae Conserved hypothetical protein 0.0107 0.0124 0.0961
Loa Loa (eye worm) transcription factor SMAD2 0.0217 0.033 0.033
Brugia malayi calpain family protein 1 0.0782 0.1386 0.1386
Plasmodium falciparum plasmepsin V 0.0114 0.0138 0.0281
Loa Loa (eye worm) hypothetical protein 0.01 0.0112 0.0112
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0089 0.0091 0.0089
Schistosoma mansoni tyrosine kinase 0.0067 0.0051 0.0051
Giardia lamblia Encystation-specific protease 0.0674 0.1185 0.3063
Loa Loa (eye worm) hypothetical protein 0.0116 0.0141 0.0141
Schistosoma mansoni hypothetical protein 0.0578 0.1004 0.1004
Loa Loa (eye worm) aspartyl protease 6 0.0114 0.0138 0.0138
Trypanosoma brucei hypothetical protein 0.0089 0.0091 0.0118
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.032 0.0523 0.0523
Brugia malayi Proteasome A-type and B-type family protein 0.0058 0.0033 0.0033
Echinococcus multilocularis survival motor neuron protein 1 0.0262 0.0414 0.0414
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0089 0.0091 0.0089
Brugia malayi SRC-1 0.0067 0.0051 0.0051
Brugia malayi aspartic protease BmAsp-2, identical 0.0114 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.1385 0.2514 0.2514
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0089 0.0091 0.0118
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0397 0.0666 0.0666
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Schistosoma mansoni hypothetical protein 0.032 0.0523 0.0523
Trypanosoma cruzi major cysteine proteinase, putative 0.0637 0.1114 0.1113
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0104 0.0118 0.0118
Plasmodium falciparum serine repeat antigen 1 0.0637 0.1114 0.2294
Loa Loa (eye worm) cysteine protease 0.2636 0.4851 0.4851
Brugia malayi EF hand family protein 0.0041 0.0002 0.0002
Schistosoma mansoni cathepsin D (A01 family) 0.1404 0.2548 0.2548
Trypanosoma brucei prolyl endopeptidase 0.0136 0.018 0.0237
Loa Loa (eye worm) hypothetical protein 0.0181 0.0264 0.0264
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0797 0.1415 0.1415
Trypanosoma cruzi major cysteine proteinase, putative 0.2054 0.3763 0.3762
Plasmodium vivax metacaspase 1, putative 0.0241 0.0375 0.077
Toxoplasma gondii microneme protein MIC17B 0.01 0.0112 0.0228
Leishmania major calpain family cysteine protease-like protein 0.0089 0.0091 0.0118
Giardia lamblia Proteasome subunit beta type 1 0.0045 0.0009 0.0016
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0244 0.0381 0.3488
Trypanosoma brucei Calpain-like protein CALP1.3 0.0089 0.0091 0.0118
Schistosoma mansoni cercarial elastase (S01 family) 0.032 0.0523 0.0523
Echinococcus multilocularis apoptotic protease activating factor 1 0.0195 0.0289 0.0289
Brugia malayi thymidylate synthase 0.0599 0.1043 0.1043
Onchocerca volvulus Arrow homolog 0.0116 0.0141 0.0291
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0637 0.1114 0.2294
Trichomonas vaginalis calcineurin B subunit, putative 0.0042 0.0002 0.0002
Mycobacterium tuberculosis Long conserved protein 0.0107 0.0124 0.0961
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0042 0.0042
Brugia malayi PAN domain containing protein 0.01 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2636 0.4851 1
Trypanosoma brucei metacaspase MCA3 0.0241 0.0375 0.0498
Echinococcus multilocularis tachykinin peptides receptor 99D 0.2058 0.3771 0.3771
Onchocerca volvulus 0.0599 0.1043 0.2151
Schistosoma mansoni tyrosine kinase 0.0067 0.0051 0.0051
Giardia lamblia Cathepsin L-like protease 0.0637 0.1114 0.2881
Echinococcus granulosus cysteine protease 0.1472 0.2676 0.2676
Trypanosoma cruzi metacaspase, putative 0.0241 0.0375 0.0373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.4054 0.75 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0082 0.0079 0.0079
Echinococcus multilocularis EF hand domain containing family member A2 0.0042 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.032 0.0523 0.0523
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0241 0.0375 0.0375
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0114 0.0138 0.0138
Plasmodium falciparum cysteine proteinase falcipain 2b 0.2636 0.4851 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0637 0.1114 0.2294
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0136 0.018 0.018
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0041 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0082 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0089 0.0091 0.0183
Echinococcus granulosus tyrosine protein kinase Fyn 0.0067 0.0051 0.0051
Echinococcus multilocularis growth factor receptor bound protein 2 0.0786 0.1395 0.1395
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0786 0.1395 0.1395
Onchocerca volvulus 0.032 0.0523 0.1078
Toxoplasma gondii microneme protein, putative 0.01 0.0112 0.0228
Schistosoma mansoni dihydrofolate reductase 0.0244 0.0381 0.0381
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0736 0.13 0.2676
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0211 0.0319 0.0319
Trypanosoma brucei cysteine peptidase, putative 0.0089 0.0091 0.0118
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0002 0.0002
Onchocerca volvulus 0.01 0.0112 0.0231
Brugia malayi calpain 5 0.0089 0.0091 0.0091
Echinococcus granulosus geminin 0.0174 0.025 0.025

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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