Detailed information for compound 418068

Basic information

Technical information
  • TDR Targets ID: 418068
  • Name: (2S)-2-amino-N-(2-methylphenyl)propanamide
  • MW: 178.231 | Formula: C10H14N2O
  • H donors: 2 H acceptors: 1 LogP: 0.95 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C([C@@H](N)C)Nc1ccccc1C
  • InChi: 1S/C10H14N2O/c1-7-5-3-4-6-9(7)12-10(13)8(2)11/h3-6,8H,11H2,1-2H3,(H,12,13)/t8-/m0/s1
  • InChiKey: BEXOMEKJRGSLNS-QMMMGPOBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-amino-N-(o-tolyl)propanamide
  • (2S)-2-azanyl-N-(2-methylphenyl)propanamide
  • (2S)-2-amino-N-(o-tolyl)propionamide
  • (2S)-2-amino-N-(2-methylphenyl)propionamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Echinococcus granulosus g protein coupled receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.0308 0.0307
Echinococcus granulosus cathepsin L cysteine protease 0.0098 0.0291 0.029
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis calbindin 32 0.0068 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0095 0.0095
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0081 0.0221 0.1239
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0385 0.1495 0.1472
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Brugia malayi EGF-like domain containing protein 0.0062 0.014 0.0139
Brugia malayi beta-lactamase family protein 0.0146 0.0492 0.0491
Loa Loa (eye worm) hypothetical protein 0.0232 0.0852 0.0851
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0081 0.0221 0.0976
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0095 0.0095
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0158 0.0157
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.009 0.0089
Schistosoma mansoni calmodulin 0.0068 0.0166 0.0166
Schistosoma mansoni patched 1 0.0044 0.0066 0.0065
Echinococcus multilocularis integrin beta 2 0.1423 0.5854 0.5854
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.0131
Mycobacterium tuberculosis Probable hydrolase 0.0146 0.0492 0.1057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2411 1 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.009 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Trypanosoma brucei centrin-3 0.013 0.0428 0.1245
Onchocerca volvulus 0.0097 0.0287 0.0964
Giardia lamblia Cathepsin B precursor 0.0802 0.3246 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.0308 0.0282
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0068 0.0166 0.014
Brugia malayi programmed cell death protein 6 0.0068 0.0166 0.0166
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0221 0.0221
Echinococcus granulosus integrin alpha ps 0.0087 0.0246 0.0245
Schistosoma mansoni immunophilin 0.0332 0.1273 0.1272
Plasmodium falciparum calpain 0.0134 0.0443 0.2765
Loa Loa (eye worm) cathepsin B 0.0802 0.3246 0.3245
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0081 0.0221 0.0221
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0098 0.0291 0.0819
Trypanosoma brucei Calpain-like protein 2 0.0134 0.0443 0.1293
Loa Loa (eye worm) hypothetical protein 0.0062 0.014 0.0139
Echinococcus multilocularis cysteine protease 0.0122 0.0392 0.0392
Brugia malayi latrophilin 2 splice variant baaae 0.0108 0.0333 0.0332
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0053 0.0102 0.0513
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0053 0.0102 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0385 0.1495 1
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0182 0.0181
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.0498 0.0497
Brugia malayi Papain family cysteine protease containing protein 0.0098 0.0291 0.029
Schistosoma mansoni hypothetical protein 0.0043 0.0059 0.0058
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0068 0.0166 0.0513
Echinococcus granulosus fibrillin 1 0.0062 0.014 0.0139
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0062 0.0207
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0095 0.0095
Trichomonas vaginalis fk506-binding protein, putative 0.0385 0.1495 0.4606
Echinococcus granulosus tachykinin peptides receptor 99D 0.0671 0.2698 0.2697
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.0852 0.0851
Echinococcus granulosus neuronal calcium sensor 0.0068 0.0166 0.0166
Entamoeba histolytica cysteine protease, putative 0.0081 0.0221 0.1323
Toxoplasma gondii EF hand domain-containing protein 0.0062 0.0142 0.0356
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0492 0.1516
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) RNA binding protein 0.0066 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.003 0.003
Echinococcus granulosus neuropeptide receptor 0.0051 0.0095 0.0095
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0221 0.0221
Schistosoma mansoni neuronal calcium sensor 0.0068 0.0166 0.0166
Toxoplasma gondii calmodulin, putative 0.0062 0.0142 0.0356
Loa Loa (eye worm) hypothetical protein 0.0062 0.0142 0.0141
Trypanosoma brucei protein I/6 0.0068 0.0166 0.0433
Entamoeba histolytica hypothetical protein 0.011 0.0341 0.2142
Brugia malayi Ets-domain containing protein 0.007 0.0174 0.0174
Echinococcus multilocularis integrin alpha 3 0.0087 0.0246 0.0245
Plasmodium vivax unspecified product 0.0098 0.0291 0.1384
Loa Loa (eye worm) cysteine protease 0.0122 0.0392 0.0392
Trichomonas vaginalis calcium binding protein, putative 0.0068 0.0166 0.0513
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.003 0.0094
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0053 0.0102 0.5
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0041 0.0033
Trypanosoma brucei Calpain-like protein CALP1.3 0.0134 0.0443 0.1293
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.173
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.0308 0.0873
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0095 0.0095
Schistosoma mansoni survival motor neuron protein 0.0047 0.0078 0.0078
Entamoeba histolytica hypothetical protein 0.0081 0.0221 0.1323
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0146 0.0492 0.0491
Brugia malayi cathepsin F-like cysteine proteinase 0.0081 0.0221 0.0221
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0095 0.0095
Trypanosoma brucei mitochondrial calcium uptake 1 0.0068 0.0166 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0049 0.0152
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0542 0.0542
Trypanosoma brucei antigen, putative 0.0446 0.1753 0.5362
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Giardia lamblia Cathepsin B precursor 0.0081 0.0221 0.0594
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0221 0.0594
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Schistosoma mansoni chromobox protein 0.0072 0.0182 0.0181
Onchocerca volvulus 0.0051 0.0095 0.0318
Echinococcus multilocularis EF hand domain containing family member A2 0.0068 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0081 0.0221 0.0682
Onchocerca volvulus 0.0051 0.0095 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0221 0.0682
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0182 0.0561
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Echinococcus granulosus calumenin 0.0068 0.0166 0.0166
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0041 0.0095
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.0477 0.0476
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Entamoeba histolytica calmodulin, putative 0.0068 0.0166 0.0949
Echinococcus multilocularis calcium uptake protein 1 0.0068 0.0166 0.0166
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0095 0.0095
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trichomonas vaginalis caltractin, putative 0.0062 0.0142 0.0436
Mycobacterium ulcerans hypothetical protein 0.0146 0.0492 0.2797
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.0308 0.0307
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0027 0.0026
Trypanosoma cruzi major cysteine proteinase, putative 0.0081 0.0221 0.0195
Brugia malayi Heterochromatin protein 1 0.0072 0.0182 0.0181
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0081 0.0221 0.0594
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Schistosoma mansoni calmodulin-related 0.0062 0.0142 0.0141
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0385 0.1495 0.4606
Plasmodium vivax vivapain-2 0.0122 0.0392 0.1983
Entamoeba histolytica grainin 2 0.0062 0.0142 0.078
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0122 0.0392 0.2415
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0068 0.0166 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0221 0.0682
Trypanosoma cruzi cysteine proteinase, putative 0.0098 0.0291 0.0264
Echinococcus multilocularis programmed cell death protein 0.013 0.0428 0.0427
Trypanosoma cruzi cysteine peptidase, putative 0.0122 0.0392 0.0366
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0053 0.0102 0.0224
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0221 0.0221
Brugia malayi EGF-like domain containing protein 0.0062 0.014 0.0139
Giardia lamblia Cathepsin L precursor 0.0081 0.0221 0.0594
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0134 0.0443 0.1365
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0062 0.0142 0.0506
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0081 0.0221 0.0976
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0802 0.3246 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Brugia malayi cathepsin Z-like cysteine proteinase 0.0081 0.0221 0.0221
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0095 0.0095
Onchocerca volvulus 0.0062 0.014 0.0469
Loa Loa (eye worm) hypothetical protein 0.1183 0.4844 0.4844
Leishmania major protein kinase, putative 0.0069 0.017 0.0445
Mycobacterium tuberculosis Probable lipase LipD 0.0146 0.0492 0.1057
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0095 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Leishmania major calmodulin, putative 0.0068 0.0166 0.0433
Loa Loa (eye worm) calpain D 0.0134 0.0443 0.0443
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0053 0.0102 0.0102
Loa Loa (eye worm) myosin Light Chain family member 0.0062 0.0142 0.0141
Schistosoma mansoni calpain-2 (C02 family) 0.0134 0.0443 0.0443
Echinococcus multilocularis neuropeptide s receptor 0.0526 0.2088 0.2088
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0069 0.017 0.0144
Schistosoma mansoni calpain-7 (C02 family) 0.0449 0.1765 0.1764
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0174 0.0174
Brugia malayi calpain 5 0.0134 0.0443 0.0443
Echinococcus multilocularis adam 0.0062 0.014 0.0139
Trichomonas vaginalis calpain, putative 0.0134 0.0443 0.1365
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0095 0.0095
Echinococcus granulosus calpain A 0.0446 0.1753 0.1752
Echinococcus multilocularis chromobox protein 1 0.0072 0.0182 0.0181
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0222 0.0813 0.0812
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0078 0.0078
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0098 0.0291 0.029
Trypanosoma brucei Calpain-like protein 1.2 0.0134 0.0443 0.1293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0095 0.0095
Trypanosoma brucei calpain, putative 0.0134 0.0443 0.1293
Trypanosoma brucei calpain, putative 0.0134 0.0443 0.1293
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0134 0.0443 0.1293
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0095 0.0095
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0095 0.0095
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0174 0.0174
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0166 0.0513
Trichomonas vaginalis centrin, putative 0.0062 0.0142 0.0436
Loa Loa (eye worm) acetyltransferase 0.0142 0.0477 0.0476
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0234
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0095 0.0095
Giardia lamblia Cathepsin B precursor 0.0802 0.3246 1
Brugia malayi calpain family protein 1 0.1183 0.4844 0.4844
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Onchocerca volvulus 0.0051 0.0095 0.0318
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.0492 0.1444
Entamoeba histolytica cysteine protease, putative 0.0081 0.0221 0.1323
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0081 0.0221 0.0682
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0095 0.0095
Echinococcus granulosus serotonin receptor 0.0051 0.0095 0.0095
Trypanosoma cruzi centrin, putative 0.013 0.0428 0.0402
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0177 0.0624 0.2097
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0291 0.1795
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0095 0.0095
Echinococcus granulosus neurocalcin 0.0068 0.0166 0.0166
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0068 0.0166 0.0166
Echinococcus multilocularis calpain A 0.1251 0.5131 0.513
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Giardia lamblia Tenascin-37 0.0062 0.014 0.0341
Onchocerca volvulus 0.0047 0.0078 0.0262
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Plasmodium falciparum serine repeat antigen 5 0.0081 0.0221 0.1239
Loa Loa (eye worm) myosin regulatory light chain 1 0.0062 0.0142 0.0141
Giardia lamblia Calmodulin 0.0062 0.0142 0.0346
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0081 0.0221 0.0221
Entamoeba histolytica cysteine protease, putative 0.0081 0.0221 0.1323
Brugia malayi ORL1-like opioid receptor 0.0051 0.0095 0.0095
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Toxoplasma gondii preprocathepsin c precursor, putative 0.0081 0.0221 0.0603
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0158 0.0157
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0068 0.0166 0.0166
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0158 0.0157
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0078 0.0078
Brugia malayi MH2 domain containing protein 0.0232 0.0856 0.0855
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.0312 0.1942
Schistosoma mansoni amine GPCR 0.0051 0.0095 0.0095
Echinococcus multilocularis Myosin regulatory light chain 0.0062 0.0142 0.0141
Entamoeba histolytica cysteine proteinase 1, putative 0.0098 0.0291 0.1795
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.0308 0.0873
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.003 0.0094
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Loa Loa (eye worm) hypothetical protein 0.0177 0.0624 0.0623
Entamoeba histolytica cysteine protease, putative 0.0122 0.0392 0.2487
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0056 0.0172
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Brugia malayi Dopamine receptor protein 2 0.0051 0.0095 0.0095
Schistosoma mansoni biogenic amine receptor 0.0051 0.0095 0.0095
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0081 0.0221 0.0976
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0446 0.1753 0.173
Trypanosoma brucei cysteine peptidase C (CPC) 0.0802 0.3246 1
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0385 0.1495 0.4606
Schistosoma mansoni transcription factor LCR-F1 0.011 0.0341 0.0341
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Trypanosoma brucei calmodulin, putative 0.0068 0.0166 0.0433
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0122 0.0392 0.0392
Echinococcus multilocularis hypothetical protein 0.0446 0.1753 0.1752
Echinococcus granulosus chromobox protein 1 0.0072 0.0182 0.0181
Schistosoma mansoni centrin-related 0.0068 0.0166 0.0166
Toxoplasma gondii calcium-dependent protein kinase 0.0069 0.017 0.0445
Echinococcus multilocularis neuronal calcium sensor 0.0068 0.0166 0.0166
Schistosoma mansoni opsin-like receptor 0.0051 0.0095 0.0095
Onchocerca volvulus 0.0032 0.0013 0.0041
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0062 0.0142 0.0474
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0053 0.0102 0.0234
Loa Loa (eye worm) hypothetical protein 0.0081 0.0221 0.0221
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1251 0.5131 0.513
Loa Loa (eye worm) hypothetical protein 0.0146 0.0492 0.0491
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0146 0.0492 0.0491
Trichomonas vaginalis esterase, putative 0.0146 0.0492 0.1516
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1183 0.4844 0.4844
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0095 0.0095
Brugia malayi EGF-like domain containing protein 0.0062 0.014 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0802 0.3246 0.3245
Schistosoma mansoni calmodulin 0.0068 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Toxoplasma gondii cathepsin B 0.0802 0.3246 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0095 0.0095
Trypanosoma cruzi major cysteine proteinase, putative 0.0081 0.0221 0.0195
Giardia lamblia Programmed cell death protein-like protein 0.0062 0.0142 0.0346
Loa Loa (eye worm) hypothetical protein 0.0122 0.0392 0.0392
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0146 0.0492 0.1057
Onchocerca volvulus 0.0146 0.0492 0.1653
Brugia malayi G-protein coupled receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0134 0.0443 0.1365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.0308 0.0873
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.0308 0.0282
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.003 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Schistosoma mansoni neuropeptide receptor 0.0051 0.0095 0.0095
Toxoplasma gondii cathepsin CPC2 0.0081 0.0221 0.0603
Entamoeba histolytica hypothetical protein 0.011 0.0341 0.2142
Brugia malayi calpain 5 0.0312 0.119 0.1189
Onchocerca volvulus Cathepsin L homolog 0.0122 0.0392 0.1318
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0095 0.0095
Trypanosoma cruzi cysteine protease, putative 0.0098 0.0291 0.0264
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0095 0.0095
Trichomonas vaginalis centrin, putative 0.0068 0.0166 0.0513
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0492 0.0491
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0102 0.0316
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0332 0.1273 0.1272
Loa Loa (eye worm) hypothetical protein 0.0146 0.0492 0.0491
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0221 0.0682
Onchocerca volvulus 0.0062 0.0142 0.0474
Schistosoma mansoni hypothetical protein 0.0853 0.346 0.346
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Onchocerca volvulus 0.0146 0.0492 0.1653
Loa Loa (eye worm) hypothetical protein 0.0081 0.0221 0.0221
Schistosoma mansoni opsin-like receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.009 0.0089
Leishmania major hypothetical protein, unknown function 0.0134 0.0443 0.1293
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Brugia malayi Trypsin family protein 0.0097 0.0287 0.0286
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0053 0.0102 0.0102
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0102 0.0234
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0492 0.1516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Echinococcus multilocularis somatostatin receptor 0.0051 0.0095 0.0095
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.0477 0.0476
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0446 0.1753 0.173
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.0443 0.0417
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0095 0.0095
Leishmania major calmodulin-like protein 0.0068 0.0166 0.0433
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.2411 1 1
Brugia malayi Latrophilin receptor protein 2 0.005 0.009 0.0089
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Giardia lamblia High cysteine protein 0.0062 0.014 0.0341
Trichomonas vaginalis fk506 binding protein, putative 0.0053 0.0102 0.0316
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0308 0.0949
Plasmodium falciparum serine repeat antigen 7 0.0081 0.0221 0.1239
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0095 0.0095
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0043 0.0059 0.0058
Onchocerca volvulus 0.0053 0.0102 0.0342
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0221 0.0682
Echinococcus granulosus chromobox protein 1 0.0072 0.0182 0.0181
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0095 0.0095
Brugia malayi N-terminal motif family protein 0.0177 0.0624 0.0623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Schistosoma mansoni neuropeptide receptor 0.0051 0.0095 0.0095
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.5362
Onchocerca volvulus Cathepsin L homolog 0.0122 0.0392 0.1318
Toxoplasma gondii centrin 0.0068 0.0166 0.0433
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0385 0.1495 0.1494
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0134 0.0443 0.0417
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0134 0.0443 0.0443
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0332 0.1273 0.1272
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0068 0.0166 0.0166
Schistosoma mansoni cathepsin F (C01 family) 0.0105 0.0323 0.0322
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.0443 0.0417
Leishmania major calcineurin B subunit, putative 0.0068 0.0166 0.0433
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0122 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus multilocularis fibrillin 2 0.0062 0.014 0.0139
Echinococcus multilocularis 0.0053 0.0102 0.0102
Leishmania major peptidylprolyl isomerase-like protein 0.0385 0.1495 0.456
Onchocerca volvulus 0.0105 0.0323 0.1085
Brugia malayi Melatonin receptor type 1A 0.0051 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0078 0.0078
Onchocerca volvulus Cathepsin F homolog 0.0122 0.0392 0.1318
Echinococcus multilocularis programmed cell death protein 6 0.0062 0.0142 0.0141
Mycobacterium ulcerans lipase LipD 0.0146 0.0492 0.2797
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0291 0.0895
Trypanosoma cruzi cysteine proteinase, putative 0.0098 0.0291 0.0264
Schistosoma mansoni cathepsin S (C01 family) 0.0081 0.0221 0.0221
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0027 0.0026
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0095 0.0095
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0081 0.0221 0.0976
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Loa Loa (eye worm) EF hand family protein 0.0068 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0032 0.0013 0.0012
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0095 0.0095
Echinococcus granulosus calmodulin 0.0068 0.0166 0.0166
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0308 0.0282
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0095 0.0095
Echinococcus granulosus Myosin regulatory light chain 0.0062 0.0142 0.0141
Schistosoma mansoni amine GPCR 0.0051 0.0095 0.0095
Leishmania major hypothetical protein, conserved 0.0068 0.0166 0.0433
Brugia malayi MAP kinase sur-1 0.0102 0.0308 0.0307
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Giardia lamblia Encystation-specific protease 0.0081 0.0221 0.0594
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2411 1 1
Plasmodium vivax calpain, putative 0.0446 0.1753 1
Echinococcus granulosus calbindin 32 0.0068 0.0166 0.0166
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0087 0.0246 0.0245
Trypanosoma brucei Calpain-like protein 1.1 0.0134 0.0443 0.1293
Echinococcus multilocularis calcyphosin protein 0.0062 0.0142 0.0141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Loa Loa (eye worm) hypothetical protein 0.0105 0.0323 0.0322
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0095 0.0095
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0146 0.0492 0.2797
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0095 0.0095
Entamoeba histolytica calcium binding family protein 0.0068 0.0166 0.0949
Plasmodium falciparum serine repeat antigen 9 0.0081 0.0221 0.1239
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.0443 0.0417
Trypanosoma cruzi conserved protein 0.0134 0.0443 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Loa Loa (eye worm) hypothetical protein 0.0062 0.014 0.0139
Echinococcus granulosus orexin receptor type 2 0.0051 0.0095 0.0095
Echinococcus multilocularis Calcium binding protein 0.0062 0.0142 0.0141
Entamoeba histolytica cysteine proteinase, putative 0.0122 0.0392 0.2487
Brugia malayi Cathepsin L-like precursor 0.0122 0.0392 0.0392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0323 0.0995
Trichomonas vaginalis calcineurin B subunit, putative 0.0068 0.0166 0.0513
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0095 0.0095
Entamoeba histolytica cysteine protease, putative 0.0081 0.0221 0.1323
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0053 0.0102 0.0234
Echinococcus multilocularis sex peptide receptor 0.0051 0.0095 0.0095
Trypanosoma brucei hypothetical protein, conserved 0.0068 0.0166 0.0433
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0146 0.0492 0.1057
Brugia malayi hypothetical protein 0.0292 0.1105 0.1105
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0446 0.1753 0.173
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0221 0.0221
Echinococcus granulosus tar DNA binding protein 0.0066 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0385 0.1495 0.1472
Trypanosoma cruzi I/6 autoantigen, putative 0.0068 0.0166 0.014
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.0312 0.0311
Schistosoma mansoni hypothetical protein 0.005 0.009 0.0089
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1222 0.501 0.501
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0221 0.0682
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.009 0.0089
Giardia lamblia Hypothetical protein 0.0053 0.0102 0.0224
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.003 0.003
Trypanosoma cruzi calmodulin, putative 0.0068 0.0166 0.014
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0095 0.0095
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0053 0.0102 0.0234
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Schistosoma mansoni integrin alpha-ps 0.0095 0.0277 0.0277
Echinococcus granulosus cathepsin b 0.2411 1 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.0308 0.0307
Loa Loa (eye worm) hypothetical protein 0.0146 0.0492 0.0491
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Toxoplasma gondii cathepsin CPL 0.0122 0.0392 0.1134
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Onchocerca volvulus 0.0122 0.0392 0.1318
Echinococcus multilocularis cathepsin L cysteine protease 0.0122 0.0392 0.0392
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Loa Loa (eye worm) hypothetical protein 0.0097 0.0287 0.0286
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.003 0.003
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0081 0.0221 0.0976
Echinococcus multilocularis cathepsin L 0.0098 0.0291 0.029
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0095 0.0095
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0446 0.1753 0.173
Trichomonas vaginalis hypothetical protein 0.0134 0.0443 0.1365
Schistosoma mansoni cathepsin C 0.0081 0.0221 0.0221
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0095 0.0318
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0385 0.1495 1
Echinococcus granulosus somatostatin receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis GPCR, family 2 0.005 0.009 0.0089
Brugia malayi neuropeptide F receptor 0.0051 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0051 0.0095 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0308 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Trichomonas vaginalis calcineurin B subunit, putative 0.0068 0.0166 0.0513
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Echinococcus granulosus cathepsin l1 0.0122 0.0392 0.0392
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0095 0.0095
Mycobacterium tuberculosis Probable esterase LipL 0.0146 0.0492 0.1057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Schistosoma mansoni calmodulin related calcium binding protein 0.0068 0.0166 0.0166
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Plasmodium falciparum cysteine proteinase falcipain 1 0.0098 0.0291 0.1716
Giardia lamblia Cysteine protease 0.0081 0.0221 0.0594
Echinococcus multilocularis protein jagged 2 0.0062 0.014 0.0139
Echinococcus granulosus cathepsin L 0.0098 0.0291 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0221 0.0682
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.011 0.0341 0.0341
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0053 0.0102 0.0234
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0095 0.0095
Brugia malayi Calcitonin receptor-like protein seb-1 0.0158 0.0542 0.0542
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0134 0.0443 0.1293
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0095 0.0095
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0385 0.1495 0.1494
Onchocerca volvulus 0.0068 0.0166 0.0558
Brugia malayi cathepsin L-like precursor 0.0105 0.0323 0.0322
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0095 0.0095
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0095 0.0095
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0221 0.0221
Schistosoma mansoni fk506 binding protein 0.0053 0.0102 0.0102
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.173
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0053 0.0102 0.0102
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0385 0.1495 1
Schistosoma mansoni hypothetical protein 0.0043 0.0059 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0122 0.0392 0.0366
Mycobacterium ulcerans beta-lactamase 0.0146 0.0492 0.2797
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0056 0.0172
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0385 0.1495 0.1494
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0221 0.0682
Leishmania major hypothetical protein, conserved 0.0146 0.0492 0.1444
Entamoeba histolytica cysteine protease, putative 0.0081 0.0221 0.1323
Leishmania major i/6 autoantigen-like protein 0.0068 0.0166 0.0433
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Brugia malayi Serotonin receptor 0.0051 0.0095 0.0095
Trypanosoma brucei cysteine peptidase, putative 0.0134 0.0443 0.1293
Trypanosoma brucei calpain-like protein, putative 0.0446 0.1753 0.5362
Schistosoma mansoni amine GPCR 0.0051 0.0095 0.0095
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.0312 0.0311
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0385 0.1495 0.4555
Echinococcus granulosus neuropeptide receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis calcium binding protein, putative 0.0068 0.0166 0.0513
Toxoplasma gondii hypothetical protein 0.0134 0.0443 0.1293
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0385 0.1495 0.1494
Loa Loa (eye worm) hypothetical protein 0.0103 0.0312 0.0311
Brugia malayi Fli-1 protein 0.0213 0.0774 0.0773
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0095 0.0095
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0385 0.1495 0.4555
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0081 0.0221 0.1323
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0158 0.0157
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0027 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0802 0.3246 1
Echinococcus multilocularis EF hand domain containing family member A2 0.0068 0.0166 0.0166
Trypanosoma cruzi centrin, putative 0.013 0.0428 0.0402
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0385 0.1495 0.1494
Schistosoma mansoni ef hand domain family member A2 0.0068 0.0166 0.0166
Schistosoma mansoni reticulocalbin 0.0068 0.0166 0.0166
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0182 0.0561
Echinococcus granulosus programmed cell death protein 6 0.0062 0.0142 0.0141
Onchocerca volvulus 0.0053 0.0102 0.0342
Trypanosoma cruzi I/6 autoantigen, putative 0.0068 0.0166 0.014
Schistosoma mansoni amine GPCR 0.0051 0.0095 0.0095
Plasmodium vivax centrin-1, putative 0.0068 0.0166 0.0652
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0036 0.003 0.003
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Brugia malayi Ets-domain containing protein 0.007 0.0174 0.0174
Trichomonas vaginalis centrin, putative 0.0068 0.0166 0.0513
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0049 0.0164
Toxoplasma gondii EFHC1, putative 0.0068 0.0166 0.0433
Schistosoma mansoni integrin beta subunit 0.1131 0.4629 0.4628
Schistosoma mansoni ets-related 0.0213 0.0774 0.0773
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0068 0.0166 0.0949
Loa Loa (eye worm) hypothetical protein 0.0871 0.3535 0.3534
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Leishmania major kinesin, putative 0.0312 0.119 0.3613
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0095 0.0095
Entamoeba histolytica calcium-binding protein, putative 0.0068 0.0166 0.0949
Echinococcus granulosus beta LACTamase domain containing family member 0.0146 0.0492 0.0491
Echinococcus granulosus g protein coupled receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0492 0.1516
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.0308 0.0863
Brugia malayi Papain family cysteine protease containing protein 0.0098 0.0291 0.029
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0446 0.1753 0.173
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0221 0.0221
Echinococcus granulosus integrin beta 2 0.1423 0.5854 0.5854
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0291 0.1795
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0098 0.0291 0.0264
Brugia malayi hypothetical protein 0.0232 0.0852 0.0851
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.0443 0.0417
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0062 0.0192
Giardia lamblia Tenascin precursor 0.0062 0.014 0.0341
Brugia malayi Cathepsin L-like precursor 0.0122 0.0392 0.0392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Echinococcus granulosus cathepsin l cysteine peptidase 0.0122 0.0392 0.0392
Schistosoma mansoni biogenic amine receptor 0.0051 0.0095 0.0095
Giardia lamblia Cathepsin B precursor 0.0081 0.0221 0.0594
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0095 0.0095
Onchocerca volvulus 0.0051 0.0095 0.0318
Toxoplasma gondii calcium binding protein precursor, putative 0.0062 0.0142 0.0356
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1251 0.5131 0.513
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0098 0.0291 0.029
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0053 0.0102 0.0224
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0385 0.1495 0.1472
Trichomonas vaginalis calpain, putative 0.0134 0.0443 0.1365
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0095 0.0095
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.0312 0.0311
Trypanosoma cruzi cysteine peptidase, putative 0.0098 0.0291 0.0264
Trypanosoma brucei calpain-like protein, putative 0.0446 0.1753 0.5362
Trichomonas vaginalis hypothetical protein 0.0062 0.014 0.0432
Leishmania major centrin, putative,caltractin, putative 0.0068 0.0166 0.0433
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0078 0.0078
Schistosoma mansoni immunophilin 0.0385 0.1495 0.1494
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0385 0.1495 1
Schistosoma mansoni neuronal calcium sensor 0.0068 0.0166 0.0166
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0053 0.0102 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Giardia lamblia Cysteine protease 0.0081 0.0221 0.0594
Brugia malayi cathepsin L-like cysteine proteinase 0.0081 0.0221 0.0221
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0081 0.0221 0.0221
Toxoplasma gondii EF hand domain-containing protein 0.0068 0.0166 0.0433
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0095 0.0095
Trichomonas vaginalis calcium binding proteins, putative 0.0068 0.0166 0.0513
Echinococcus granulosus integrin alpha ps 0.0182 0.0643 0.0642
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1251 0.5131 0.513
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0068 0.0166 0.0949
Schistosoma mansoni calpain C (C02 family) 0.0446 0.1753 0.1752
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0095 0.0095
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.5362
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0385 0.1495 0.1494
Loa Loa (eye worm) transcription factor SMAD2 0.0232 0.0856 0.0855
Echinococcus multilocularis chromobox protein 1 0.0072 0.0182 0.0181
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0146 0.0492 0.0491
Schistosoma mansoni hypothetical protein 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0081 0.0221 0.0221
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0053 0.0102 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Giardia lamblia Cysteine protease 0.0081 0.0221 0.0594
Brugia malayi RNA binding protein 0.0066 0.0158 0.0157
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.009 0.0089
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0323 0.0995
Loa Loa (eye worm) calpain 0.0446 0.1753 0.1752
Trypanosoma brucei centrin, putative 0.0068 0.0166 0.0433
Leishmania major hypothetical protein, conserved 0.0068 0.0166 0.0433
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0062 0.0142 0.0436
Trichomonas vaginalis myosin light chain 1, putative 0.0068 0.0166 0.0513
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0134 0.0443 0.0417
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0081 0.0221 0.0976
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.0308 0.0873
Onchocerca volvulus 0.0051 0.0095 0.0318
Leishmania major centrin, putative 0.0068 0.0166 0.0433
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.0443 0.0417
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0027 0.0084
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0027 0.0084
Entamoeba histolytica hypothetical protein 0.011 0.0341 0.2142
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0027 0.0026
Schistosoma mansoni hypothetical protein 0.005 0.009 0.0089
Leishmania major calpain family cysteine protease-like protein 0.0134 0.0443 0.1293
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.003 0.001
Giardia lamblia Tenascin-X 0.0062 0.014 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0308 0.0949
Giardia lamblia Cathepsin L precursor 0.0081 0.0221 0.0594
Echinococcus multilocularis calmodulin 0.0068 0.0166 0.0166
Echinococcus multilocularis integrin alpha ps 0.0182 0.0643 0.0642
Onchocerca volvulus 0.0297 0.1129 0.3796
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0087 0.0246 0.0245
Plasmodium vivax vivapain-3 0.0098 0.0291 0.1384
Echinococcus multilocularis integrin alpha ps 0.0087 0.0246 0.0245
Echinococcus multilocularis programmed cell death protein 0.013 0.0428 0.0427
Schistosoma mansoni hypothetical protein 0.0051 0.0095 0.0095
Trichomonas vaginalis immunophilin, putative 0.0385 0.1495 0.4606
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0142 0.0115
Echinococcus multilocularis cathepsin L cysteine protease 0.0122 0.0392 0.0392
Schistosoma mansoni cathepsin B (C01 family) 0.0081 0.0221 0.0221
Trichomonas vaginalis calmodulin-2, putative 0.0068 0.0166 0.0513
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.046 0.046
Brugia malayi putative neuropeptide receptor 0.0051 0.0095 0.0095
Onchocerca volvulus 0.0086 0.0242 0.0811
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0122 0.0392 0.1208
Trichomonas vaginalis conserved hypothetical protein 0.0134 0.0443 0.1365
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0095 0.0095
Brugia malayi Dopamine receptor 0.0051 0.0095 0.0095
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0053 0.0102 0.0075
Toxoplasma gondii troponin c, isotype gamma, putative 0.0068 0.0166 0.0433
Entamoeba histolytica cysteine proteinase, putative 0.0122 0.0392 0.2487
Leishmania major cysteine peptidase A (CPA) 0.0122 0.0392 0.1134
Echinococcus multilocularis serotonin receptor 0.0051 0.0095 0.0095
Brugia malayi Cathepsin L-like precursor 0.0122 0.0392 0.0392
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0053 0.0102 0.0075
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0134 0.0443 0.0417
Echinococcus granulosus fmrfamide receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Onchocerca volvulus 0.0122 0.0392 0.1318
Entamoeba histolytica grainin 2 0.013 0.0428 0.273
Loa Loa (eye worm) MH2 domain-containing protein 0.0232 0.0856 0.0855
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) ctsf protein 0.0122 0.0392 0.0392
Mycobacterium tuberculosis Probable lipase LipE 0.0146 0.0492 0.1057
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus multilocularis protein patched 0.0044 0.0066 0.0065
Leishmania major hypothetical protein, conserved 0.0134 0.0443 0.1293
Entamoeba histolytica hypothetical protein, conserved 0.0068 0.0166 0.0949
Loa Loa (eye worm) hypothetical protein 0.0108 0.0333 0.0332
Brugia malayi Cathepsin L-like precursor 0.0122 0.0392 0.0392
Toxoplasma gondii calmodulin CAM1 0.0068 0.0166 0.0433
Trichomonas vaginalis calcium binding protein, putative 0.0068 0.0166 0.0513
Schistosoma mansoni hypothetical protein 0.0087 0.0246 0.0245
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0095 0.0095
Onchocerca volvulus 0.0051 0.0095 0.0318
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Loa Loa (eye worm) FKBP5 protein 0.0385 0.1495 0.1494
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0095 0.0095
Mycobacterium tuberculosis Conserved protein 0.0146 0.0492 0.1057
Onchocerca volvulus 0.0122 0.0392 0.1318
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.0319 0.0318
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0308 0.0949
Echinococcus granulosus adam 0.0062 0.014 0.0139
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0234
Loa Loa (eye worm) hypothetical protein 0.0097 0.0287 0.0286
Echinococcus multilocularis neurocalcin 0.0068 0.0166 0.0166
Echinococcus granulosus fibrillin 2 0.0062 0.014 0.0139
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0095 0.0095
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0081 0.0221 0.0221
Brugia malayi sulfakinin receptor protein 0.0051 0.0095 0.0095
Echinococcus granulosus EF HAND 1 calcium binding site 0.0068 0.0166 0.0166
Giardia lamblia Cysteine protease 0.0081 0.0221 0.0594
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0027 0.0084
Brugia malayi calcium-binding protein 0.0068 0.0166 0.0166
Echinococcus multilocularis beta LACTamase domain containing family member 0.0146 0.0492 0.0491
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0095 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Echinococcus multilocularis calpain family protein 1, d 0.0871 0.3535 0.3534
Schistosoma mansoni myosin regulatory light chain 0.0062 0.0142 0.0141
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1251 0.5131 0.513
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0105 0.0323 0.0297
Plasmodium falciparum serine repeat antigen 6 0.0081 0.0221 0.1239
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.0852 0.0851
Echinococcus granulosus hypothetical protein 0.0051 0.0095 0.0095
Plasmodium falciparum serine repeat antigen 3 0.0081 0.0221 0.1239
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0062 0.0142 0.0474
Schistosoma mansoni calpain (C02 family) 0.0446 0.1753 0.1752
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Brugia malayi GnHR receptor homolog 0.0051 0.0095 0.0095
Trypanosoma brucei Component of motile flagella 41 0.0068 0.0166 0.0433
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0095 0.0095
Brugia malayi EF hand family protein 0.0068 0.0166 0.0166
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0385 0.1495 0.848
Onchocerca volvulus 0.0051 0.0095 0.0318
Echinococcus granulosus cathepsin b 0.2411 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0095 0.0095
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Giardia lamblia Cathepsin B precursor 0.0802 0.3246 1
Onchocerca volvulus 0.0122 0.0392 0.1318
Giardia lamblia High cysteine protein 0.0062 0.014 0.0341
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0134 0.0443 0.1365
Echinococcus granulosus cysteine protease 0.0098 0.0291 0.029
Leishmania major fk506-binding protein 1-like protein 0.0385 0.1495 0.456
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0095 0.0095
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0097 0.0287 0.0286
Trypanosoma brucei hypothetical protein 0.0134 0.0443 0.1293
Brugia malayi calpain family protein 1 0.1183 0.4844 0.4844
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0134 0.0443 0.1365
Giardia lamblia Cathepsin L precursor 0.0081 0.0221 0.0594
Mycobacterium tuberculosis Probable oxidoreductase 0.028 0.1054 0.2583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0134 0.0443 0.1365
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.5362
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0422
Schistosoma mansoni neuronal calcium sensor 0.0068 0.0166 0.0166
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0081 0.0221 0.0976
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0081 0.0221 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0221 0.0682
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0081 0.0221 0.0221
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0053 0.0102 0.0102
Entamoeba histolytica cysteine protease, putative 0.0081 0.0221 0.1323
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0027 0.0084
Loa Loa (eye worm) hypothetical protein 0.0081 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.003 0.0003
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0134 0.0443 0.1293
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0134 0.0443 0.1365
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0158 0.0157
Loa Loa (eye worm) programmed cell death protein 6 0.0068 0.0166 0.0166
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.0443 0.0417
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0134 0.0443 0.0443
Schistosoma mansoni alpha-glucosidase 0.0136 0.045 0.0449
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0062 0.014 0.0139
Echinococcus multilocularis expressed conserved protein 0.0097 0.0286 0.0285
Trypanosoma cruzi cysteine peptidase, putative 0.0122 0.0392 0.0366
Plasmodium vivax vivapain-2 0.0122 0.0392 0.1983
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0221 0.0221
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0053 0.0102 0.5
Toxoplasma gondii centrin family protein 0.0062 0.0142 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Trichomonas vaginalis calmodulin, putative 0.0062 0.0142 0.0436
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0068 0.0166 0.014
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Brugia malayi hypothetical protein 0.011 0.0341 0.0341
Brugia malayi cathepsin L precursor 0.0081 0.0221 0.0221
Echinococcus granulosus calpain 7 C02 family 0.0446 0.1753 0.1752
Brugia malayi Myosin regulatory light chain 1 0.0062 0.0142 0.0141
Mycobacterium tuberculosis Conserved protein 0.0146 0.0492 0.1057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2411 1 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.011 0.0341 0.0341
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Onchocerca volvulus 0.0068 0.0166 0.0558
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.173
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0065
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0802 0.3246 0.3246
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0056 0.0089
Trypanosoma cruzi centrin-3 0.013 0.0428 0.0402
Giardia lamblia Hypothetical protein 0.0068 0.0166 0.0423
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0027 0.0084
Entamoeba histolytica grainin, putative 0.0068 0.0166 0.0949
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0081 0.0221 0.0682
Loa Loa (eye worm) calpain family protein 1 0.1183 0.4844 0.4844
Loa Loa (eye worm) hypothetical protein 0.0105 0.0323 0.0322
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Brugia malayi TAR-binding protein 0.0066 0.0158 0.0157
Trypanosoma brucei protein kinase, putative 0.0102 0.0308 0.0873
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0135 0.0445 0.1299
Brugia malayi calpain 7 0.0446 0.1753 0.1752
Trypanosoma cruzi kinesin, putative 0.0312 0.119 0.1166
Echinococcus granulosus EF hand domain containing family member A2 0.0068 0.0166 0.0166
Toxoplasma gondii ABC1 family protein 0.0146 0.0492 0.1444
Loa Loa (eye worm) hypothetical protein 0.0062 0.0142 0.0141
Loa Loa (eye worm) hypothetical protein 0.0737 0.2972 0.2971
Brugia malayi CHE-14 protein 0.0044 0.0066 0.0065
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0134 0.0443 0.0417
Schistosoma mansoni centrin 0.0068 0.0166 0.0166
Giardia lamblia Cathepsin B precursor 0.0081 0.0221 0.0594
Onchocerca volvulus 0.0091 0.0263 0.0883
Echinococcus granulosus calcyphosin protein 0.0062 0.0142 0.0141
Trichomonas vaginalis fk506-binding protein, putative 0.0053 0.0102 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.003 0.0094
Echinococcus multilocularis integrin alpha ps 0.0182 0.0643 0.0642
Echinococcus granulosus cathepsin L 0.0081 0.0221 0.0221
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0068 0.0166 0.0166
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0066 0.0065
Giardia lamblia Cathepsin L precursor 0.0081 0.0221 0.0594
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0056 0.0089
Trichomonas vaginalis calpain, putative 0.0134 0.0443 0.1365
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0385 0.1495 0.456
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0308 0.0282
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0446 0.1753 0.173
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.0498 0.0497
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0095 0.0095
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0385 0.1495 1
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Mycobacterium leprae Probable lipase LipE 0.0146 0.0492 1
Schistosoma mansoni amine GPCR 0.0051 0.0095 0.0095
Giardia lamblia Neurogenic locus Notch protein precursor 0.0062 0.014 0.0341
Onchocerca volvulus 0.0068 0.0166 0.0558
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0075
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0221 0.0682
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0221 0.0682
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2411 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0095 0.0095
Trichomonas vaginalis calcium binding protein, putative 0.013 0.0428 0.1318
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Onchocerca volvulus 0.0122 0.0392 0.1318
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0221 0.0594
Brugia malayi G-protein coupled receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0291 0.0895
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.0477 0.0476
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Echinococcus granulosus FK506 binding protein 2 0.0053 0.0102 0.0102
Entamoeba histolytica calpain large subunit domain III containing protein 0.0312 0.119 0.7922
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0492 0.1516
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Brugia malayi G protein-coupled receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0066 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0098 0.0291 0.0819
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0068 0.0166 0.0166
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0385 0.1495 0.1472
Brugia malayi EGF-like domain containing protein 0.0062 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0095 0.0095
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0095 0.0318
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Echinococcus multilocularis serotonin receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis calmodulin, putative 0.013 0.0428 0.1318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0221 0.0682
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0095 0.0095
Entamoeba histolytica calmodulin, putative 0.0062 0.0142 0.078
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0492 0.1516
Trypanosoma brucei centrin, putative 0.0068 0.0166 0.0433
Leishmania major programmed cell death 6 protein-like protein 0.0068 0.0166 0.0433
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0095 0.0095
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0446 0.1753 0.5362
Echinococcus granulosus centrin 2 0.0068 0.0166 0.0166
Leishmania major cathepsin L-like protease 0.0122 0.0392 0.1134
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.0095 0.0095
Schistosoma mansoni myosin regulatory light chain 0.0062 0.0142 0.0141
Giardia lamblia Cathepsin L-like protease 0.0081 0.0221 0.0594
Loa Loa (eye worm) hypothetical protein 0.0292 0.1105 0.1105
Schistosoma mansoni myosin light chain 0.0062 0.0142 0.0141
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0105 0.0323 0.0322
Toxoplasma gondii calmodulin CAM2 0.0062 0.0142 0.0356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Echinococcus granulosus calcium uptake protein 1 0.0068 0.0166 0.0166
Entamoeba histolytica hypothetical protein 0.011 0.0341 0.2142
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0078 0.0078
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0053 0.0102 0.0102
Echinococcus granulosus EF hand domain containing family member A2 0.0068 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0062 0.0142 0.0141
Brugia malayi neuropeptide F receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0053 0.0102 0.0102
Schistosoma mansoni neuronal calcium sensor 0.0068 0.0166 0.0166
Plasmodium falciparum cysteine proteinase falcipain 3 0.0122 0.0392 0.2415
Schistosoma mansoni integrin alpha 0.0182 0.0643 0.0642
Schistosoma mansoni mitochondrial solute carrier 0.0068 0.0166 0.0166
Schistosoma mansoni Mername-AA248 (C02 family) 0.0446 0.1753 0.1752
Toxoplasma gondii cathepsin CPC1 0.0081 0.0221 0.0603
Onchocerca volvulus 0.0051 0.0095 0.0318
Trichomonas vaginalis caltractin, putative 0.0062 0.0142 0.0436
Schistosoma mansoni hypothetical protein 0.0043 0.0059 0.0058
Schistosoma mansoni integrin alpha-ps 0.0182 0.0643 0.0642
Trypanosoma brucei kinesin, putative 0.0312 0.119 0.3613
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0081 0.0221 0.0976
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) fli-1 protein 0.0213 0.0774 0.0773
Echinococcus granulosus neuropeptide s receptor 0.0526 0.2088 0.2088
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0062 0.014 0.0432
Brugia malayi cathepsin Z-like cysteine proteinase 0.0081 0.0221 0.0221
Schistosoma mansoni hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi caltractin, putative 0.0068 0.0166 0.014
Mycobacterium ulcerans short chain dehydrogenase 0.028 0.1054 0.6836
Schistosoma mansoni hypothetical protein 0.0108 0.0333 0.0332
Schistosoma mansoni rab 0.0068 0.0166 0.0166
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0221 0.0594
Plasmodium falciparum centrin-1 0.0068 0.0166 0.0862
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0081 0.0221 0.1239
Brugia malayi Kelch motif family protein 0.0292 0.1105 0.1105
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0053 0.0102 0.0102
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0221 0.0743
Brugia malayi AKH receptor 0.0051 0.0095 0.0095
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.0323 0.2015
Schistosoma mansoni reticulocalbin 0.0068 0.0166 0.0166
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0069 0.017 0.0144
Schistosoma mansoni immunophilin 0.0385 0.1495 0.1494
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Loa Loa (eye worm) hypothetical protein 0.0062 0.014 0.0139
Mycobacterium ulcerans esterase/lipase LipP 0.0146 0.0492 0.2797
Loa Loa (eye worm) integrin beta-2 0.1825 0.7539 0.7539
Trypanosoma cruzi calmodulin, putative 0.0068 0.0166 0.014
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0069 0.017 0.0675
Brugia malayi follicle stimulating hormone receptor 0.0051 0.0095 0.0095
Schistosoma mansoni myosin xvIII 0.0051 0.0095 0.0095
Echinococcus multilocularis neuropeptide receptor A26 0.0526 0.2088 0.2088
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0853 0.346 0.346
Loa Loa (eye worm) calpain 5 0.0312 0.119 0.1189
Giardia lamblia Hypothetical protein 0.0081 0.0221 0.0594
Giardia lamblia Cathepsin L-like protease 0.0081 0.0221 0.0594
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0221 0.0682
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0081 0.0221 0.0221
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0158 0.0542 0.0542
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0027 0.0084
Plasmodium falciparum serine repeat antigen 8 0.0081 0.0221 0.1239
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0056 0.0055
Echinococcus granulosus programmed cell death protein 0.013 0.0428 0.0427
Leishmania major phospholipase c-like protein 0.0068 0.0166 0.0433
Brugia malayi Neuronal calcium sensor family protein 1 0.0062 0.0142 0.0141
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0221 0.0221
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0068 0.0166 0.0166
Echinococcus multilocularis calpain 7 (C02 family) 0.0446 0.1753 0.1752
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0098 0.0291 0.029
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.009 0.0089
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0146 0.0492 0.1057
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0292 0.1105 0.1105
Giardia lamblia Neurogenic locus notch-like protein 0.0062 0.014 0.0341
Leishmania major calmodulin, putative 0.0068 0.0166 0.0433
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0053 0.0102 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Echinococcus multilocularis calumenin 0.0068 0.0166 0.0166
Trichomonas vaginalis calcium binding protein, putative 0.0062 0.0142 0.0436
Echinococcus granulosus cathepsin l1 0.0105 0.0323 0.0322
Echinococcus granulosus neuropeptide receptor A26 0.0526 0.2088 0.2088
Loa Loa (eye worm) hypothetical protein 0.1049 0.4281 0.4281
Loa Loa (eye worm) hypothetical protein 0.0146 0.0492 0.0491
Entamoeba histolytica cysteine proteinase 2 0.0098 0.0291 0.1795
Leishmania major calmodulin-like protein 0.0068 0.0166 0.0433
Brugia malayi Integrin alpha pat-2 precursor 0.0182 0.0643 0.0642
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0385 0.1495 0.1494
Echinococcus granulosus expressed conserved protein 0.0097 0.0286 0.0285
Echinococcus multilocularis protein dispatched 1 0.005 0.0092 0.0091
Echinococcus multilocularis cathepsin b 0.2411 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0078 0.0078
Echinococcus granulosus Calcium binding protein 0.0062 0.0142 0.0141
Brugia malayi Dopamine receptor protein 1 0.0051 0.0095 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0102 0.0316
Brugia malayi Cathepsin L-like precursor 0.0122 0.0392 0.0392
Echinococcus granulosus geminin 0.0853 0.346 0.346
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Giardia lamblia Tenascin-like 0.0062 0.014 0.0341
Echinococcus granulosus calpain 5 0.0446 0.1753 0.1752
Trichomonas vaginalis centrin, putative 0.0062 0.0142 0.0436
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.011 0.0341 0.0341
Plasmodium vivax serine-repeat antigen (SERA) 0.0081 0.0221 0.0976
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0027 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0221 0.0682
Plasmodium falciparum serine repeat antigen 4 0.0081 0.0221 0.1239
Schistosoma mansoni neuropeptide receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis fibrillin 1 0.0075 0.0195 0.0194
Loa Loa (eye worm) hypothetical protein 0.005 0.009 0.0089
Trypanosoma brucei caltractin, putative 0.013 0.0428 0.1245
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0068 0.0166 0.0433
Onchocerca volvulus 0.0122 0.0392 0.1318
Schistosoma mansoni gabp alpha 0.007 0.0174 0.0174
Onchocerca volvulus 0.0051 0.0095 0.0318
Onchocerca volvulus 0.0062 0.0142 0.0474
Giardia lamblia Cathepsin L precursor 0.0081 0.0221 0.0594
Onchocerca volvulus 0.0051 0.0095 0.0318
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0049 0.0152
Onchocerca volvulus 0.0146 0.0492 0.1653
Entamoeba histolytica protein kinase, putative 0.0313 0.1194 0.7948
Schistosoma mansoni hypothetical protein 0.005 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0054 0.0107 0.0107
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0542 0.0542
Trypanosoma brucei I/6 autoantigen 0.0068 0.0166 0.0433
Trichomonas vaginalis centrin, putative 0.0062 0.0142 0.0436
Trichomonas vaginalis kakapo, putative 0.0062 0.0142 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0221 0.0682
Plasmodium vivax unspecified product 0.0081 0.0221 0.0976
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.0392 0.1208
Loa Loa (eye worm) beta-lactamase 0.0146 0.0492 0.0491
Schistosoma mansoni hypothetical protein 0.0068 0.0166 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0095 0.0095
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0068 0.0166 0.0513
Brugia malayi calpain D 0.0134 0.0443 0.0443
Toxoplasma gondii hypothetical protein 0.0062 0.014 0.0351
Brugia malayi beta-lactamase family protein 0.0146 0.0492 0.0491
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0492 0.0466
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.0095 0.0095
Plasmodium vivax serine-repeat antigen (SERA) 0.0081 0.0221 0.0976
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0027 0.0084
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.1293
Loa Loa (eye worm) hypothetical protein 0.0146 0.0492 0.0491
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.0308 0.0307
Giardia lamblia Hypothetical protein 0.0081 0.0221 0.0594
Onchocerca volvulus 0.0051 0.0095 0.0318
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.003 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Echinococcus multilocularis centrin 2 0.0068 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Brugia malayi Probable myosin regulatory light chain 0.0062 0.0142 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0078 0.0078
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0062 0.0192
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0513
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Echinococcus granulosus GPCR family 2 0.005 0.009 0.0089
Schistosoma mansoni adenoreceptor 0.0051 0.0095 0.0095
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0095 0.0095
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0291 0.1795
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0081 0.0221 0.1239
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0492 0.0491
Brugia malayi Papain family cysteine protease containing protein 0.0122 0.0392 0.0392
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0078 0.0078
Echinococcus multilocularis cathepsin b 0.2411 1 1
Echinococcus granulosus allatostatin A receptor 0.0051 0.0095 0.0095
Onchocerca volvulus 0.0122 0.0392 0.1318
Loa Loa (eye worm) calpain family protein 1 0.0871 0.3535 0.3534
Giardia lamblia hypothetical protein 0.0062 0.014 0.0341
Trypanosoma cruzi calmodulin, putative 0.0068 0.0166 0.014
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.003 0.003
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.003 0.003
Onchocerca volvulus 0.0051 0.0095 0.0318
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) integrin alpha pat-2 0.0182 0.0643 0.0642
Brugia malayi Integrin beta pat-3 precursor 0.1825 0.7539 0.7539
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0291 0.1795
Brugia malayi Cathepsin L-like precursor 0.0122 0.0392 0.0392
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0671 0.2698 0.2697
Schistosoma mansoni hypothetical protein 0.0053 0.0102 0.0102
Trypanosoma cruzi cysteine peptidase, putative 0.0122 0.0392 0.0366
Echinococcus multilocularis geminin 0.0853 0.346 0.346
Brugia malayi RasGEF domain containing protein 0.0064 0.015 0.015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0078 0.0078
Leishmania major calpain protease-like protein 0.0134 0.0443 0.1293
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0081 0.0221 0.0682
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0095 0.0095
Brugia malayi Cathepsin L-like precursor 0.0105 0.0323 0.0322
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Schistosoma mansoni hypothetical protein 0.005 0.009 0.0089
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0158 0.0542 0.0542
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.0308 0.0307
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2411 1 1
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0174 0.0174
Trichomonas vaginalis fk506-binding protein, putative 0.0053 0.0102 0.0316
Trypanosoma cruzi kinesin, putative 0.0312 0.119 0.1166
Trypanosoma cruzi cruzipain precursor, putative 0.0122 0.0392 0.0366
Echinococcus multilocularis fk506 binding protein 0.0385 0.1495 0.1494
Brugia malayi fibroinase precursor 0.0081 0.0221 0.0221
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0053 0.0102 0.0075
Schistosoma mansoni cathepsin F (C01 family) 0.0122 0.0392 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0142 0.0436
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0095 0.0095
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0158 0.0157
Onchocerca volvulus 0.0081 0.0221 0.0743
Schistosoma mansoni alpha-glucosidase 0.0136 0.045 0.0449
Mycobacterium tuberculosis Conserved protein 0.0146 0.0492 0.1057
Loa Loa (eye worm) calmodulin-like protein 0.0068 0.0166 0.0166
Leishmania major centrin, putative 0.0068 0.0166 0.0433
Schistosoma mansoni chromobox protein 0.0072 0.0182 0.0181
Mycobacterium leprae conserved hypothetical protein 0.0146 0.0492 1
Brugia malayi Cathepsin L-like precursor 0.0105 0.0323 0.0322
Schistosoma mansoni opsin-like receptor 0.0051 0.0095 0.0095
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0081 0.0221 0.0976
Echinococcus multilocularis cysteine protease 0.0122 0.0392 0.0392
Brugia malayi Cathepsin L-like cysteine proteinase 0.0105 0.0323 0.0322
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Echinococcus granulosus g protein coupled receptor 0.0051 0.0095 0.0095
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0221 0.0221
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.173
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0166 0.0652
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0095 0.0095
Echinococcus granulosus integrin alpha 3 0.0087 0.0246 0.0245
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0122 0.0392 0.2415
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Giardia lamblia Cathepsin L precursor 0.0081 0.0221 0.0594
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0542 0.0542
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0053 0.0102 0.0234
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0075
Brugia malayi hypothetical protein 0.0297 0.1129 0.1128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis calpain 0.0446 0.1753 0.1752
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0081 0.0221 0.1323
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Entamoeba histolytica calmodulin, putative 0.0068 0.0166 0.0949
Onchocerca volvulus 0.0051 0.0095 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0221 0.0682
Onchocerca volvulus 0.0051 0.0095 0.0318
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0068 0.0166 0.014
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0446 0.1753 0.5362
Schistosoma mansoni histamine h1 receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.0392 0.1208
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0931 0.3788 1
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0385 0.1495 0.456
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis calmodulin 0.0068 0.0166 0.0166
Echinococcus granulosus calpain 0.0446 0.1753 0.1752
Echinococcus multilocularis cathepsin L 0.0081 0.0221 0.0221
Giardia lamblia Cathepsin B precursor 0.0081 0.0221 0.0594
Echinococcus granulosus cathepsin L cysteine proteinase 0.0122 0.0392 0.0392
Echinococcus granulosus sex peptide receptor 0.0051 0.0095 0.0095
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0102 0.0275
Brugia malayi chromobox protein homolog 3 0.004 0.0049 0.0049
Brugia malayi RE15519p 0.0051 0.0095 0.0095
Schistosoma mansoni biogenic amine receptor 0.0051 0.0095 0.0095
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0081 0.0221 0.0976
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0095 0.0095
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0308 0.0949
Brugia malayi Calmodulin-like protein 0.0068 0.0166 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0166 0.0513
Loa Loa (eye worm) hypothetical protein 0.0087 0.0246 0.0245
Entamoeba histolytica calpain family cysteine protease, putative 0.0134 0.0443 0.2834
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0095 0.0095
Plasmodium falciparum centrin-4 0.0062 0.0142 0.0691
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0122 0.0392 0.0392
Brugia malayi larval opioid receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0027 0.0084
Schistosoma mansoni integrin alpha-4 0.0777 0.3143 0.3143
Plasmodium falciparum serine repeat antigen 1 0.0081 0.0221 0.1239
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0122 0.0392 0.0392
Trichomonas vaginalis calmodulin, putative 0.0068 0.0166 0.0513
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0542 0.0542
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0095 0.0095
Brugia malayi Serotonin receptor 0.0051 0.0095 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0122 0.0392 0.1208
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0802 0.3246 0.3227
Loa Loa (eye worm) fibroinase 0.0122 0.0392 0.0392
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0068 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0332 0.1273 0.1272
Loa Loa (eye worm) hypothetical protein 0.0068 0.0166 0.0166
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0542 0.0542
Onchocerca volvulus 0.0051 0.0095 0.0318
Echinococcus multilocularis calpain 5 0.0446 0.1753 0.1752
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0095 0.0095
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0095 0.0095
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0053 0.0102 0.0234
Loa Loa (eye worm) hypothetical protein 0.0081 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095
Entamoeba histolytica cysteine protease, putative 0.0098 0.0291 0.1795
Plasmodium vivax vivapain-1 0.0098 0.0291 0.1384
Schistosoma mansoni cathepsin F (C01 family) 0.0122 0.0392 0.0392
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.0095 0.0095
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0492 0.0466
Schistosoma mansoni calpain-7 (C02 family) 0.0449 0.1765 0.1764
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0158 0.0542 0.0542
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0069 0.017 0.0445
Onchocerca volvulus 0.0051 0.0095 0.0318
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0097 0.0287 0.0286
Trypanosoma brucei calmodulin, putative 0.0068 0.0166 0.0433
Onchocerca volvulus 0.0051 0.0095 0.0318
Brugia malayi hypothetical protein 0.0051 0.0095 0.0095
Toxoplasma gondii centrin, putative 0.0068 0.0166 0.0433
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0095 0.0095
Trypanosoma brucei calpain-like protein, putative 0.0446 0.1753 0.5362
Plasmodium vivax hypothetical protein, conserved 0.0146 0.0492 0.257
Brugia malayi EF hand family protein 0.0068 0.0166 0.0166
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0066 0.0065
Echinococcus granulosus calpain A 0.1251 0.5131 0.513
Loa Loa (eye worm) hypothetical protein 0.0297 0.1129 0.1128
Schistosoma mansoni alpha glucosidase 0.0035 0.0027 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0122 0.0392 0.1134
Onchocerca volvulus 0.0737 0.2972 1
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0053 0.0102 0.0224
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0078 0.0078
Plasmodium falciparum serine repeat antigen 2 0.0081 0.0221 0.1239
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.0443 0.0417
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0095 0.0095
Trypanosoma brucei calpain-like protein, putative 0.0446 0.1753 0.5362
Brugia malayi beta-lactamase 0.0146 0.0492 0.0491
Schistosoma mansoni neuropeptide receptor 0.0051 0.0095 0.0095
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0095 0.0095
Giardia lamblia Cathepsin B precursor 0.0081 0.0221 0.0594
Loa Loa (eye worm) hypothetical protein 0.0051 0.0095 0.0095

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 16.2 s Antinociceptive effect in Swiss Albino mouse assessed as licking latency at 15 mg/kg, sc after 15 mins by hot-plate test ChEMBL. 17373780
Activity (functional) = 16.2 s Antinociceptive effect in Swiss Albino mouse assessed as licking latency at 15 mg/kg, sc after 15 mins by hot-plate test ChEMBL. 17373780

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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