Detailed information for compound 418070

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 616.516 | Formula: C26H29N6O10P
  • H donors: 4 H acceptors: 6 LogP: 1.73 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOC(=O)[C@@H](NP(=O)(Oc1ccccc1)OC[C@@]1(N=[N+]=[N-])O[C@H]([C@H]([C@H]1O)O)n1ccc(=O)[nH]c1=O)Cc1ccccc1
  • InChi: 1S/C26H29N6O10P/c1-2-39-24(36)19(15-17-9-5-3-6-10-17)29-43(38,42-18-11-7-4-8-12-18)40-16-26(30-31-27)22(35)21(34)23(41-26)32-14-13-20(33)28-25(32)37/h3-14,19,21-23,34-35H,2,15-16H2,1H3,(H,29,38)(H,28,33,37)/t19-,21-,22+,23+,26+,43?/m0/s1
  • InChiKey: WDPZFXYUJPNREG-PZAKEBMYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0223 0.022
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0018
Brugia malayi CHE-14 protein 0.0041 0.0078 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0223 0.0207
Loa Loa (eye worm) hypothetical protein 0.007 0.0223 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0112 0.0333
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Onchocerca volvulus 0.0106 0.0403 0.1778
Schistosoma mansoni cathepsin F (C01 family) 0.0106 0.0403 0.0401
Schistosoma mansoni hypothetical protein 0.004 0.007 0.0068
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0078 0.0076
Echinococcus multilocularis neuropeptide s receptor 0.0452 0.2152 0.215
Echinococcus granulosus programmed cell death protein 6 0.0055 0.0148 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.006 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Echinococcus multilocularis neuropeptide receptor A26 0.0452 0.2152 0.215
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0223 0.0979
Onchocerca volvulus 0.0048 0.0112 0.0485
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0223 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0214 0.065
Entamoeba histolytica cysteine proteinase, putative 0.0106 0.0403 0.4203
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0068 0.0214 0.0212
Mycobacterium ulcerans lipase LipD 0.007 0.0223 0.2245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0214 0.065
Schistosoma mansoni hypothetical protein 0.0179 0.0771 0.0769
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0106 0.0403 0.0401
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0029 0.0016 0.5
Mycobacterium leprae conserved hypothetical protein 0.007 0.0223 1
Leishmania major calpain family cysteine protease-like protein 0.0086 0.0304 0.0892
Onchocerca volvulus 0.0106 0.0403 0.1778
Plasmodium falciparum cysteine proteinase falcipain 3 0.0106 0.0403 0.4203
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0048 0.0112 0.0333
Entamoeba histolytica grainin 2 0.0055 0.0148 0.143
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.1301
Schistosoma mansoni immunophilin 0.0182 0.079 0.0788
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Entamoeba histolytica cysteine protease, putative 0.0068 0.0214 0.2155
Onchocerca volvulus 0.0029 0.0016 0.006
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Echinococcus granulosus FK506 binding protein 2 0.0029 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.0048 0.0112 0.0109
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0219 0.2201
Giardia lamblia Cathepsin L precursor 0.0068 0.0214 0.0615
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0219 0.0628
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Echinococcus multilocularis EF hand domain containing family member A2 0.0048 0.0112 0.0109
Entamoeba histolytica hypothetical protein 0.0068 0.0214 0.2155
Trichomonas vaginalis calpain, putative 0.0086 0.0304 0.0926
Entamoeba histolytica cysteine protease, putative 0.0068 0.0214 0.2155
Echinococcus multilocularis centrin 2 0.0048 0.0112 0.0109
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0286 0.1315 0.4027
Echinococcus multilocularis cysteine protease 0.0106 0.0403 0.0401
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0068 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.007 0.0223 0.0223
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Trypanosoma cruzi kinesin, putative 0.02 0.088 0.0865
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0068 0.0214 0.1528
Loa Loa (eye worm) calpain 0.0286 0.1315 0.1315
Loa Loa (eye worm) hypothetical protein 0.0473 0.2256 0.2256
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0223 0.0207
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0211 0.0937 0.2855
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0119 0.0355
Entamoeba histolytica calmodulin, putative 0.0055 0.0148 0.143
Leishmania major hypothetical protein, unknown function 0.0086 0.0304 0.0892
Entamoeba histolytica hypothetical protein 0.007 0.0224 0.2258
Trichomonas vaginalis calmodulin, putative 0.0103 0.039 0.1193
Echinococcus multilocularis neurocalcin 0.0048 0.0112 0.0109
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0049 0.0115 0.0307
Onchocerca volvulus Cathepsin L homolog 0.0068 0.0214 0.0941
Schistosoma mansoni hypothetical protein 0.0069 0.0216 0.0214
Schistosoma mansoni hypothetical protein 0.0032 0.003 0.0027
Plasmodium vivax centrin-1, putative 0.0048 0.0112 0.0736
Giardia lamblia Cysteine protease 0.0068 0.0214 0.0615
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Toxoplasma gondii cathepsin CPL 0.0106 0.0403 0.12
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0291 0.0852
Echinococcus granulosus cathepsin b 0.2006 1 1
Schistosoma mansoni calmodulin-related 0.0055 0.0148 0.0145
Brugia malayi RasGEF domain containing protein 0.0055 0.0148 0.0145
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0078 0.0078
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0211 0.0937 0.7091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Loa Loa (eye worm) cathepsin B 0.0668 0.3241 0.3241
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0223 0.0979
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0106 0.0403 0.1233
Brugia malayi programmed cell death protein 6 0.0048 0.0112 0.0109
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0048 0.0112 0.0296
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.003 0.0027
Entamoeba histolytica cysteine protease, putative 0.0106 0.0403 0.4203
Loa Loa (eye worm) myosin Light Chain family member 0.0055 0.0148 0.0148
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Schistosoma mansoni calmodulin related calcium binding protein 0.0048 0.0112 0.0109
Plasmodium vivax calpain, putative 0.0286 0.1315 1
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0048 0.0112 0.0109
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0119 0.0319
Trichomonas vaginalis caltractin, putative 0.0055 0.0148 0.0444
Trypanosoma brucei calpain, putative 0.0086 0.0304 0.0892
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0807 0.3944 0.3942
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Giardia lamblia Cathepsin L precursor 0.0068 0.0214 0.0615
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0068 0.0214 0.0212
Echinococcus multilocularis calpain 7 (C02 family) 0.0286 0.1315 0.1313
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0055 0.0148 0.0645
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.002 0.002
Echinococcus multilocularis Myosin regulatory light chain 0.0055 0.0148 0.0145
Trypanosoma cruzi calmodulin, putative 0.0048 0.0112 0.0096
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0086 0.0304 0.0892
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0029 0.0016 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0066 0.0204 0.0204
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0068 0.0214 0.0214
Echinococcus granulosus GPCR family 2 0.0032 0.003 0.0027
Trypanosoma brucei calpain-like protein, putative 0.0286 0.1315 0.4027
Brugia malayi Papain family cysteine protease containing protein 0.0106 0.0403 0.0401
Echinococcus granulosus programmed cell death protein 0.0103 0.039 0.0388
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0219 0.2201
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0304 0.0288
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0565 0.0563
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0068 0.0214 0.0615
Leishmania major calmodulin, putative 0.0048 0.0112 0.0296
Loa Loa (eye worm) hypothetical protein 0.0759 0.3701 0.3701
Schistosoma mansoni centrin-related 0.0048 0.0112 0.0109
Schistosoma mansoni neuronal calcium sensor 0.0048 0.0112 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0106 0.0403 0.1233
Onchocerca volvulus 0.0029 0.0016 0.006
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Echinococcus granulosus Calcium binding protein 0.0055 0.0148 0.0145
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0403 0.0388
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0002 0.0002
Trypanosoma brucei antigen, putative 0.0286 0.1315 0.4027
Toxoplasma gondii cathepsin CPC2 0.0068 0.0214 0.0615
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0211 0.0937 0.0935
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0216 0.0214
Loa Loa (eye worm) fibroinase 0.0106 0.0403 0.0403
Trichomonas vaginalis fk506-binding protein, putative 0.0211 0.0937 0.2882
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0066 0.0204 0.0202
Echinococcus multilocularis cathepsin L cysteine protease 0.0106 0.0403 0.0401
Onchocerca volvulus 0.007 0.0223 0.0978
Echinococcus granulosus chromobox protein 1 0.0067 0.0209 0.0207
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0046 0.0102 0.0102
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0048 0.0112 0.0109
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0092 0.009
Schistosoma mansoni calmodulin 0.0048 0.0112 0.0109
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0377 0.0374
Giardia lamblia Cathepsin B precursor 0.0068 0.0214 0.0615
Trypanosoma cruzi cysteine proteinase, putative 0.0084 0.0291 0.0275
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0074 0.0318
Onchocerca volvulus 0.0048 0.0112 0.0485
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0048 0.0112 0.0109
Loa Loa (eye worm) calpain D 0.0086 0.0304 0.0304
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0029 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.01 0.0377 0.0377
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0211 0.0937 0.2882
Mycobacterium ulcerans hypothetical protein 0.007 0.0223 0.2245
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0068 0.0214 0.0214
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0086 0.0304 0.0288
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0086 0.0304 0.0926
Loa Loa (eye worm) hypothetical protein 0.0026 0.0002 0.0002
Trypanosoma brucei caltractin, putative 0.0103 0.039 0.1161
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0086 0.0304 0.0288
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0068 0.0214 0.0212
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0119 0.0103
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0029 0.0016 0.5
Echinococcus multilocularis integrin beta 2 0.0225 0.1007 0.1005
Trichomonas vaginalis centrin, putative 0.0055 0.0148 0.0444
Plasmodium vivax vivapain-2 0.0106 0.0403 0.298
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.0291 0.2985
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0084 0.0291 0.0886
Schistosoma mansoni neuronal calcium sensor 0.0048 0.0112 0.0109
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0084 0.0291 0.0275
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0668 0.3241 0.323
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0448 0.2129 1
Toxoplasma gondii calcium binding protein precursor, putative 0.0055 0.0148 0.0408
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Loa Loa (eye worm) programmed cell death protein 6 0.0048 0.0112 0.0112
Trichomonas vaginalis calcium binding protein, putative 0.0055 0.0148 0.0444
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0182 0.018
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Giardia lamblia Cathepsin B precursor 0.0668 0.3241 1
Entamoeba histolytica hypothetical protein 0.007 0.0224 0.2258
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0119 0.0355
Loa Loa (eye worm) hypothetical protein 0.0041 0.0078 0.0078
Echinococcus multilocularis cathepsin L cysteine protease 0.0106 0.0403 0.0401
Echinococcus multilocularis hypothetical protein 0.0286 0.1315 0.1313
Trichomonas vaginalis calcium binding proteins, putative 0.0048 0.0112 0.0333
Echinococcus granulosus cathepsin l1 0.0091 0.0327 0.0324
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0086 0.0304 0.0892
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2006 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0223 0.0979
Echinococcus multilocularis programmed cell death protein 0.0103 0.039 0.0388
Trichomonas vaginalis fk506 binding protein, putative 0.0029 0.0016 0.0037
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.1301
Trichomonas vaginalis calcineurin B subunit, putative 0.0048 0.0112 0.0333
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0304 0.0288
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0068 0.0214 0.0212
Trypanosoma cruzi centrin, putative 0.0103 0.039 0.0375
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Schistosoma mansoni myosin light chain 0.0055 0.0148 0.0145
Loa Loa (eye worm) hypothetical protein 0.0673 0.3267 0.3267
Trypanosoma cruzi major cysteine proteinase, putative 0.0068 0.0214 0.0199
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0403 0.0388
Trypanosoma brucei cysteine peptidase C (CPC) 0.0668 0.3241 1
Entamoeba histolytica calcium-binding protein, putative 0.0048 0.0112 0.1038
Schistosoma mansoni calpain-7 (C02 family) 0.0286 0.1315 0.1313
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Echinococcus multilocularis cathepsin b 0.2006 1 1
Echinococcus multilocularis calcium uptake protein 1 0.0048 0.0112 0.0109
Trichomonas vaginalis immunophilin, putative 0.0211 0.0937 0.2882
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0214 0.065
Trypanosoma brucei Calpain-like protein 2 0.0086 0.0304 0.0892
Brugia malayi TAR-binding protein 0.0062 0.0182 0.018
Schistosoma mansoni patched 1 0.0041 0.0078 0.0076
Schistosoma mansoni chromobox protein 0.0067 0.0209 0.0207
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0068 0.0214 0.1528
Brugia malayi Integrin beta pat-3 precursor 0.0304 0.1405 0.1403
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0291 0.0852
Trypanosoma cruzi conserved protein 0.0086 0.0304 0.0288
Entamoeba histolytica hypothetical protein 0.007 0.0224 0.2258
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.003 0.0027
Schistosoma mansoni hypothetical protein 0.004 0.007 0.0068
Echinococcus granulosus neuropeptide s receptor 0.0452 0.2152 0.215
Toxoplasma gondii centrin, putative 0.0048 0.0112 0.0296
Giardia lamblia Cathepsin B precursor 0.0068 0.0214 0.0615
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0211 0.0937 0.2855
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0086 0.0304 0.0926
Schistosoma mansoni cathepsin C 0.0068 0.0214 0.0212
Onchocerca volvulus 0.0055 0.0148 0.0645
Echinococcus granulosus calpain 5 0.0286 0.1315 0.1313
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0086 0.0304 0.0892
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0304 0.0288
Echinococcus multilocularis 0.0029 0.0016 0.0014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0304 0.0288
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.1301
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0048 0.0112 0.0333
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0119 0.0103
Trypanosoma cruzi centrin-3 0.0103 0.039 0.0375
Loa Loa (eye worm) hypothetical protein 0.0046 0.0102 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0304 0.0926
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0119 0.0116
Echinococcus multilocularis calmodulin 0.0048 0.0112 0.0109
Toxoplasma gondii centrin family protein 0.0055 0.0148 0.0408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0068 0.0214 0.065
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0119 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0068 0.0214 0.065
Brugia malayi cathepsin L precursor 0.0068 0.0214 0.0212
Schistosoma mansoni cathepsin F (C01 family) 0.0091 0.0327 0.0324
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0182 0.018
Brugia malayi calpain D 0.0086 0.0304 0.0301
Loa Loa (eye worm) EF hand family protein 0.0048 0.0112 0.0112
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0219 0.0216
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0223 0.0641
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0119 0.0116
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0148 0.0444
Schistosoma mansoni hypothetical protein 0.0032 0.003 0.0027
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0214 0.065
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0112 0.0333
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0068 0.0214 0.0615
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Echinococcus granulosus cathepsin L cysteine protease 0.0084 0.0291 0.0289
Loa Loa (eye worm) hypothetical protein 0.0055 0.0148 0.0148
Onchocerca volvulus 0.0091 0.0327 0.1439
Leishmania major protein kinase, putative 0.0049 0.0115 0.0307
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.003 0.0027
Schistosoma mansoni mitochondrial solute carrier 0.0048 0.0112 0.0109
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0063 0.0189 0.0187
Echinococcus multilocularis cathepsin L 0.0084 0.0291 0.0289
Trichomonas vaginalis esterase, putative 0.007 0.0223 0.0676
Schistosoma mansoni hypothetical protein 0.0048 0.0112 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0214 0.065
Leishmania major hypothetical protein, conserved 0.0048 0.0112 0.0296
Echinococcus granulosus calmodulin 0.0048 0.0112 0.0109
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0068 0.0214 0.2155
Entamoeba histolytica calpain large subunit domain III containing protein 0.02 0.088 0.9384
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0403 0.0388
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0182 0.018
Trichomonas vaginalis caltractin, putative 0.0055 0.0148 0.0444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Loa Loa (eye worm) hypothetical protein 0.0091 0.0327 0.0327
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0211 0.0937 1
Brugia malayi Cathepsin L-like precursor 0.0091 0.0327 0.0324
Trypanosoma brucei protein I/6 0.0048 0.0112 0.0296
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0223 0.0223
Schistosoma mansoni hypothetical protein 0.004 0.007 0.0068
Echinococcus granulosus calpain A 0.0807 0.3944 0.3942
Brugia malayi fibroinase precursor 0.0068 0.0214 0.0212
Brugia malayi Latrophilin receptor protein 2 0.0032 0.003 0.0027
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0106 0.0403 0.0403
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Brugia malayi calpain 5 0.02 0.088 0.0878
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Plasmodium falciparum serine repeat antigen 1 0.0068 0.0214 0.2155
Echinococcus multilocularis calpain 0.0286 0.1315 0.1313
Toxoplasma gondii troponin c, isotype gamma, putative 0.0048 0.0112 0.0296
Trypanosoma brucei I/6 autoantigen 0.0048 0.0112 0.0296
Brugia malayi Neuronal calcium sensor family protein 1 0.0055 0.0148 0.0145
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0112 0.0736
Toxoplasma gondii calmodulin CAM1 0.0048 0.0112 0.0296
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0182 0.018
Schistosoma mansoni neuronal calcium sensor 0.0048 0.0112 0.0109
Brugia malayi cathepsin Z-like cysteine proteinase 0.0068 0.0214 0.0212
Echinococcus multilocularis programmed cell death protein 0.0103 0.039 0.0388
Plasmodium falciparum serine repeat antigen 7 0.0068 0.0214 0.2155
Trypanosoma cruzi calmodulin, putative 0.0048 0.0112 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0214 0.065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Trichomonas vaginalis fk506-binding protein, putative 0.0029 0.0016 0.0037
Echinococcus multilocularis protein dispatched 1 0.0047 0.0108 0.0105
Schistosoma mansoni hypothetical protein 0.004 0.007 0.0068
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Giardia lamblia Cathepsin B precursor 0.0668 0.3241 1
Echinococcus multilocularis programmed cell death protein 6 0.0055 0.0148 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0068 0.0214 0.065
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0049 0.0115 0.0099
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0068 0.0214 0.0615
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Trichomonas vaginalis calcium binding protein, putative 0.0048 0.0112 0.0333
Trichomonas vaginalis calcium binding protein, putative 0.0103 0.039 0.1193
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0119 0.0355
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0211 0.0937 0.0935
Trichomonas vaginalis myosin light chain 1, putative 0.0048 0.0112 0.0333
Echinococcus multilocularis cathepsin L 0.0068 0.0214 0.0212
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0223 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.006 0.0172
Trypanosoma brucei kinesin, putative 0.02 0.088 0.2679
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0016 0.0037
Plasmodium vivax serine-repeat antigen (SERA) 0.0068 0.0214 0.1528
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.003 0.003
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0356 0.0354
Giardia lamblia Cathepsin B precursor 0.0068 0.0214 0.0615
Loa Loa (eye worm) hypothetical protein 0.0091 0.0327 0.0327
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0068 0.0214 0.065
Echinococcus granulosus cathepsin l1 0.0106 0.0403 0.0401
Onchocerca volvulus Cathepsin L homolog 0.0106 0.0403 0.1778
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0182 0.018
Schistosoma mansoni reticulocalbin 0.0048 0.0112 0.0109
Brugia malayi Papain family cysteine protease containing protein 0.0068 0.0214 0.0212
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Loa Loa (eye worm) hypothetical protein 0.007 0.0223 0.0223
Giardia lamblia Hypothetical protein 0.0068 0.0214 0.0615
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0223 0.0979
Brugia malayi Heterochromatin protein 1 0.0067 0.0209 0.0207
Mycobacterium tuberculosis Conserved protein 0.007 0.0223 0.0979
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0092 0.009
Trypanosoma cruzi kinesin, putative 0.02 0.088 0.0865
Toxoplasma gondii ABC1 family protein 0.007 0.0223 0.0641
Leishmania major hypothetical protein, conserved 0.007 0.0223 0.0641
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Echinococcus granulosus calcium uptake protein 1 0.0048 0.0112 0.0109
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0223 0.2245
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0304 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0119 0.0116
Giardia lamblia Cathepsin B precursor 0.0068 0.0214 0.0615
Plasmodium falciparum serine repeat antigen 9 0.0068 0.0214 0.2155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0224 0.0222
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0068 0.0214 0.1528
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0356 0.0354
Echinococcus granulosus calpain A 0.0286 0.1315 0.1313
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0356 0.3692
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0106 0.0403 0.0401
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0048 0.0112 0.0109
Echinococcus granulosus calpain 7 C02 family 0.0286 0.1315 0.1313
Leishmania major centrin, putative 0.0048 0.0112 0.0296
Entamoeba histolytica cysteine proteinase, putative 0.0091 0.0327 0.3373
Onchocerca volvulus 0.0106 0.0403 0.1778
Plasmodium falciparum calpain 0.0086 0.0304 0.3124
Toxoplasma gondii hypothetical protein 0.0086 0.0304 0.0892
Entamoeba histolytica cysteine proteinase 2 0.0084 0.0291 0.2985
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0078 0.0229
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0066 0.0204 0.0202
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0092 0.009
Toxoplasma gondii centrin 0.0048 0.0112 0.0296
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0029 0.0016 0.0014
Brugia malayi Papain family cysteine protease containing protein 0.0084 0.0291 0.0289
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0074 0.0217
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0304
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0209 0.0209
Leishmania major centrin, putative 0.0048 0.0112 0.0296
Leishmania major fk506-binding protein 1-like protein 0.0211 0.0937 0.2855
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0092 0.0092
Giardia lamblia Cathepsin L precursor 0.0068 0.0214 0.0615
Echinococcus multilocularis calpain 5 0.0286 0.1315 0.1313
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0106 0.0403 0.4203
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0068 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0106 0.0403 0.0403
Echinococcus multilocularis cysteine protease 0.0106 0.0403 0.0401
Echinococcus multilocularis calumenin 0.0048 0.0112 0.0109
Brugia malayi hypothetical protein 0.0046 0.0102 0.01
Brugia malayi MAP kinase sur-1 0.0049 0.0119 0.0116
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0807 0.3944 0.3942
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Onchocerca volvulus 0.0055 0.0148 0.0645
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0048 0.0112 0.0096
Loa Loa (eye worm) calpain 5 0.02 0.088 0.088
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0211 0.0937 0.0922
Brugia malayi Papain family cysteine protease containing protein 0.0068 0.0214 0.0212
Giardia lamblia Cathepsin L precursor 0.0068 0.0214 0.0615
Echinococcus granulosus cathepsin L 0.0084 0.0291 0.0289
Trypanosoma cruzi cysteine peptidase, putative 0.0084 0.0291 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0148 0.0132
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0068 0.0214 0.0615
Schistosoma mansoni rab 0.0048 0.0112 0.0109
Loa Loa (eye worm) hypothetical protein 0.0068 0.0214 0.0214
Trypanosoma cruzi I/6 autoantigen, putative 0.0048 0.0112 0.0096
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0068 0.0214 0.0214
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.4027
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0211 0.0937 0.0935
Schistosoma mansoni neuronal calcium sensor 0.0048 0.0112 0.0109
Brugia malayi calpain family protein 1 0.0759 0.3701 0.37
Schistosoma mansoni cathepsin B (C01 family) 0.0068 0.0214 0.0212
Brugia malayi Cathepsin L-like precursor 0.0106 0.0403 0.0401
Trichomonas vaginalis calcium binding protein, putative 0.0048 0.0112 0.0333
Entamoeba histolytica grainin 2 0.0103 0.039 0.4064
Brugia malayi Calmodulin-like protein 0.0048 0.0112 0.0109
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.1315 0.1301
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0219 0.2201
Plasmodium falciparum centrin-4 0.0055 0.0148 0.143
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0086 0.0304 0.0926
Toxoplasma gondii EF hand domain-containing protein 0.0055 0.0148 0.0408
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0223 0.022
Schistosoma mansoni centrin 0.0048 0.0112 0.0109
Echinococcus granulosus Myosin regulatory light chain 0.0055 0.0148 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0304 0.0288
Plasmodium falciparum centrin-1 0.0048 0.0112 0.1038
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0211 0.0937 0.0922
Brugia malayi beta-lactamase family protein 0.007 0.0223 0.022
Echinococcus multilocularis cathepsin b 0.2006 1 1
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0048 0.0112 0.1038
Schistosoma mansoni calpain-2 (C02 family) 0.0086 0.0304 0.0301
Loa Loa (eye worm) hypothetical protein 0.0068 0.0214 0.0214
Entamoeba histolytica calmodulin, putative 0.0048 0.0112 0.1038
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0068 0.0214 0.065
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0016
Loa Loa (eye worm) integrin beta-2 0.0304 0.1405 0.1405
Brugia malayi EF hand family protein 0.0048 0.0112 0.0109
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0182 0.079 0.0788
Echinococcus granulosus cathepsin L 0.0068 0.0214 0.0212
Echinococcus multilocularis chromobox protein 1 0.0067 0.0209 0.0207
Brugia malayi EF hand family protein 0.0048 0.0112 0.0109
Leishmania major programmed cell death 6 protein-like protein 0.0048 0.0112 0.0296
Loa Loa (eye worm) hypothetical protein 0.0068 0.0214 0.0214
Trypanosoma brucei Calpain-like protein 1.1 0.0086 0.0304 0.0892
Loa Loa (eye worm) calmodulin-like protein 0.0048 0.0112 0.0112
Trichomonas vaginalis centrin, putative 0.0055 0.0148 0.0444
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Leishmania major i/6 autoantigen-like protein 0.0048 0.0112 0.0296
Leishmania major calmodulin, putative 0.0048 0.0112 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0211 0.0937 0.0935
Onchocerca volvulus 0.0106 0.0403 0.1778
Giardia lamblia Cathepsin L precursor 0.0068 0.0214 0.0615
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0759 0.3701 0.37
Loa Loa (eye worm) calpain family protein 1 0.0759 0.3701 0.3701
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0078 0.0076
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.0291 0.2985
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0068 0.0214 0.1528
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Echinococcus multilocularis expressed conserved protein 0.0091 0.0326 0.0324
Onchocerca volvulus 0.0106 0.0403 0.1778
Echinococcus multilocularis GPCR, family 2 0.0032 0.003 0.0027
Toxoplasma gondii calcium-dependent protein kinase 0.0049 0.0115 0.0307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0086 0.0304 0.0926
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.1315 0.1301
Plasmodium falciparum serine repeat antigen 4 0.0068 0.0214 0.2155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0084 0.0291 0.0886
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0219 0.0959
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Schistosoma mansoni calpain-7 (C02 family) 0.0286 0.1315 0.1313
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0029 0.0016 0.0016
Echinococcus granulosus tar DNA binding protein 0.0062 0.0182 0.018
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0211 0.0937 0.2855
Toxoplasma gondii cathepsin CPC1 0.0068 0.0214 0.0615
Trypanosoma brucei centrin, putative 0.0048 0.0112 0.0296
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0211 0.0937 1
Entamoeba histolytica calpain family cysteine protease, putative 0.0086 0.0304 0.3124
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.1315 0.1301
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0224 0.0222
Trichomonas vaginalis hypothetical protein 0.0086 0.0304 0.0926
Leishmania major calpain protease-like protein 0.0086 0.0304 0.0892
Plasmodium vivax unspecified product 0.0068 0.0214 0.1528
Trypanosoma brucei Calpain-like protein CALP1.3 0.0086 0.0304 0.0892
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Loa Loa (eye worm) beta-lactamase 0.007 0.0223 0.0223
Giardia lamblia Cathepsin L-like protease 0.0068 0.0214 0.0615
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0092 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0668 0.3241 1
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0112 0.1038
Echinococcus granulosus calpain 0.0286 0.1315 0.1313
Schistosoma mansoni hypothetical protein 0.0179 0.0771 0.0769
Leishmania major calcineurin B subunit, putative 0.0048 0.0112 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0214 0.065
Echinococcus granulosus EF hand domain containing family member A2 0.0048 0.0112 0.0109
Brugia malayi cathepsin L-like cysteine proteinase 0.0068 0.0214 0.0212
Leishmania major centrin, putative,caltractin, putative 0.0048 0.0112 0.0296
Leishmania major calmodulin-like protein 0.0048 0.0112 0.0296
Echinococcus granulosus neuronal calcium sensor 0.0048 0.0112 0.0109
Echinococcus granulosus calumenin 0.0048 0.0112 0.0109
Brugia malayi Cathepsin L-like precursor 0.0091 0.0327 0.0324
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0119 0.0116
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0048 0.0112 0.0096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0668 0.3241 0.3239
Plasmodium falciparum serine repeat antigen 2 0.0068 0.0214 0.2155
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0068 0.0214 0.1528
Loa Loa (eye worm) ctsf protein 0.0106 0.0403 0.0403
Trichomonas vaginalis centrin, putative 0.0048 0.0112 0.0333
Schistosoma mansoni integrin beta subunit 0.0179 0.0774 0.0771
Echinococcus granulosus neuropeptide receptor A26 0.0452 0.2152 0.215
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0807 0.3944 0.3942
Trypanosoma brucei mitochondrial calcium uptake 1 0.0048 0.0112 0.0296
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0209 0.0633
Mycobacterium tuberculosis Conserved protein 0.007 0.0223 0.0979
Trichomonas vaginalis kakapo, putative 0.0055 0.0148 0.0444
Leishmania major peptidylprolyl isomerase-like protein 0.0211 0.0937 0.2855
Giardia lamblia Cathepsin L-like protease 0.0068 0.0214 0.0615
Onchocerca volvulus 0.0068 0.0214 0.0941
Brugia malayi Cathepsin L-like precursor 0.0106 0.0403 0.0401
Brugia malayi cathepsin F-like cysteine proteinase 0.0068 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.007 0.0223 0.0223
Echinococcus granulosus centrin 2 0.0048 0.0112 0.0109
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0048 0.0112 0.1038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Echinococcus granulosus cathepsin L cysteine proteinase 0.0106 0.0403 0.0401
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0068 0.0214 0.1528
Plasmodium vivax vivapain-3 0.0084 0.0291 0.2117
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.4027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0214 0.065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Leishmania major kinesin, putative 0.02 0.088 0.2679
Toxoplasma gondii calmodulin CAM2 0.0055 0.0148 0.0408
Schistosoma mansoni immunophilin 0.0211 0.0937 0.0935
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0182 0.0182
Leishmania major hypothetical protein, conserved 0.0086 0.0304 0.0892
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0364 0.0361
Schistosoma mansoni calpain (C02 family) 0.0286 0.1315 0.1313
Loa Loa (eye worm) RNA binding protein 0.0062 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0048 0.0112 0.0112
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0211 0.0937 0.0922
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0219 0.0628
Brugia malayi cathepsin L-like precursor 0.0091 0.0327 0.0324
Loa Loa (eye worm) hypothetical protein 0.0068 0.0214 0.0214
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0223 0.0979
Entamoeba histolytica cysteine protease, putative 0.0068 0.0214 0.2155
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Brugia malayi Papain family cysteine protease containing protein 0.0068 0.0214 0.0212
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0286 0.1315 0.1301
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0048 0.0112 0.0096
Brugia malayi cathepsin Z-like cysteine proteinase 0.0068 0.0214 0.0212
Loa Loa (eye worm) cysteine protease 0.0106 0.0403 0.0403
Echinococcus multilocularis fk506 binding protein 0.0211 0.0937 0.0935
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0182 0.018
Trypanosoma brucei calpain-like protein, putative 0.0286 0.1315 0.4027
Leishmania major cysteine peptidase A (CPA) 0.0106 0.0403 0.12
Onchocerca volvulus 0.007 0.0223 0.0978
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.1315 0.1301
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0066 0.0204 0.0202
Brugia malayi Kelch motif family protein 0.0046 0.0102 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.0327 0.0997
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0068 0.0214 0.2155
Entamoeba histolytica protein kinase, putative 0.0201 0.0883 0.942
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0211 0.0937 0.0937
Trichomonas vaginalis centrin, putative 0.0048 0.0112 0.0333
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Schistosoma mansoni calmodulin 0.0048 0.0112 0.0109
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0055 0.0148 0.0645
Echinococcus multilocularis calmodulin 0.0048 0.0112 0.0109
Echinococcus granulosus integrin beta 2 0.0225 0.1007 0.1005
Leishmania major phospholipase c-like protein 0.0048 0.0112 0.0296
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.006 0.0254
Trichomonas vaginalis calmodulin, putative 0.0055 0.0148 0.0444
Trypanosoma brucei protein kinase, putative 0.0049 0.0119 0.0319
Entamoeba histolytica calmodulin, putative 0.0048 0.0112 0.1038
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0211 0.0937 0.0935
Brugia malayi calpain 5 0.0086 0.0304 0.0301
Brugia malayi Myosin regulatory light chain 1 0.0055 0.0148 0.0145
Loa Loa (eye worm) hypothetical protein 0.0069 0.0216 0.0216
Brugia malayi calpain 7 0.0286 0.1315 0.1313
Echinococcus multilocularis calbindin 32 0.0048 0.0112 0.0109
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0211 0.0937 1
Toxoplasma gondii cathepsin B 0.0668 0.3241 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0224 0.0222
Entamoeba histolytica cysteine protease, putative 0.0068 0.0214 0.2155
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0223 0.2245
Schistosoma mansoni cathepsin S (C01 family) 0.0068 0.0214 0.0212
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2006 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0377 0.0377
Echinococcus granulosus EF hand domain containing family member A2 0.0048 0.0112 0.0109
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0049 0.0115 0.0099
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0356 0.0354
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0565 0.0563
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.0291 0.2985
Entamoeba histolytica cysteine protease, putative 0.0068 0.0214 0.2155
Onchocerca volvulus 0.003 0.0018 0.0071
Loa Loa (eye worm) hypothetical protein 0.0068 0.0214 0.0214
Trypanosoma cruzi major cysteine proteinase, putative 0.0068 0.0214 0.0199
Trypanosoma cruzi calmodulin, putative 0.0048 0.0112 0.0096
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0084 0.0291 0.0289
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0182 0.079 0.0788
Plasmodium vivax unspecified product 0.0084 0.0291 0.2117
Onchocerca volvulus 0.0106 0.0403 0.1778
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.1301
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0068 0.0214 0.2155
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0211 0.0937 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.0327 0.0997
Schistosoma mansoni chromobox protein 0.0067 0.0209 0.0207
Trypanosoma brucei cysteine peptidase, putative 0.0086 0.0304 0.0892
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.007 0.0223 0.0223
Giardia lamblia Programmed cell death protein-like protein 0.0055 0.0148 0.0408
Plasmodium falciparum serine repeat antigen 8 0.0068 0.0214 0.2155
Entamoeba histolytica grainin, putative 0.0048 0.0112 0.1038
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0223 0.022
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0211 0.0937 0.2882
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0223 0.0676
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0223 0.0676
Loa Loa (eye worm) hypothetical protein 0.0068 0.0214 0.0214
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Schistosoma mansoni hypothetical protein 0.0029 0.0016 0.0014
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0055 0.0148 0.0444
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Trypanosoma brucei centrin-3 0.0103 0.039 0.1161
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.0125 0.0125
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0223 0.0979
Trypanosoma brucei Component of motile flagella 41 0.0048 0.0112 0.0296
Brugia malayi Probable myosin regulatory light chain 0.0055 0.0148 0.0145
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0068 0.0214 0.1528
Brugia malayi Cathepsin L-like precursor 0.0106 0.0403 0.0401
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0119 0.0319
Entamoeba histolytica cysteine proteinase, putative 0.0106 0.0403 0.4203
Trypanosoma brucei Calpain-like protein 1.2 0.0086 0.0304 0.0892
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0078 0.0076
Leishmania major hypothetical protein, conserved 0.0048 0.0112 0.0296
Echinococcus granulosus calbindin 32 0.0048 0.0112 0.0109
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0068 0.0214 0.1528
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0211 0.0937 0.0922
Trypanosoma brucei calmodulin, putative 0.0048 0.0112 0.0296
Brugia malayi RNA binding protein 0.0062 0.0182 0.018
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0219 0.0216
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0377 0.0374
Giardia lamblia Cysteine protease 0.0068 0.0214 0.0615
Trypanosoma cruzi cysteine proteinase, putative 0.0084 0.0291 0.0275
Loa Loa (eye worm) myosin regulatory light chain 1 0.0055 0.0148 0.0148
Brugia malayi calpain family protein 1 0.0759 0.3701 0.37
Trichomonas vaginalis calmodulin-2, putative 0.0048 0.0112 0.0333
Trypanosoma cruzi I/6 autoantigen, putative 0.0048 0.0112 0.0096
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0223 0.0979
Onchocerca volvulus 0.007 0.0223 0.0978
Onchocerca volvulus Cathepsin F homolog 0.0106 0.0403 0.1778
Plasmodium falciparum serine repeat antigen 6 0.0068 0.0214 0.2155
Schistosoma mansoni hypothetical protein 0.0086 0.0304 0.0301
Brugia malayi Papain family cysteine protease containing protein 0.0084 0.0291 0.0289
Echinococcus multilocularis calpain A 0.0807 0.3944 0.3942
Giardia lamblia Cathepsin B precursor 0.0068 0.0214 0.0615
Onchocerca volvulus 0.0473 0.2256 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0084 0.0291 0.0289
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0068 0.0214 0.2155
Schistosoma mansoni Mername-AA248 (C02 family) 0.0286 0.1315 0.1313
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0068 0.0214 0.0212
Plasmodium vivax serine-repeat antigen (SERA) 0.0068 0.0214 0.1528
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0214 0.065
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2006 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Plasmodium falciparum cysteine proteinase falcipain 1 0.0084 0.0291 0.2985
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0223 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0214 0.065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2006 1 1
Schistosoma mansoni hypothetical protein 0.0032 0.003 0.0027
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.0291 0.2985
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0668 0.3241 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0084 0.0291 0.2985
Brugia malayi Cathepsin L-like cysteine proteinase 0.0091 0.0327 0.0324
Giardia lamblia Hypothetical protein 0.0048 0.0112 0.0296
Schistosoma mansoni myosin regulatory light chain 0.0055 0.0148 0.0145
Leishmania major cathepsin L-like protease 0.0106 0.0403 0.12
Trypanosoma brucei calpain, putative 0.0086 0.0304 0.0892
Plasmodium vivax vivapain-1 0.0084 0.0291 0.2117
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0086 0.0304 0.0926
Toxoplasma gondii preprocathepsin c precursor, putative 0.0068 0.0214 0.0615
Echinococcus granulosus geminin 0.0179 0.0771 0.0769
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0029 0.0016 0.0014
Brugia malayi Cathepsin L-like precursor 0.0106 0.0403 0.0401
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0119 0.0319
Brugia malayi Cathepsin L-like precursor 0.0106 0.0403 0.0401
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0119 0.0116
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0068 0.0214 0.0212
Toxoplasma gondii EF hand domain-containing protein 0.0048 0.0112 0.0296
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0068 0.0214 0.1528
Schistosoma mansoni myosin regulatory light chain 0.0055 0.0148 0.0145
Echinococcus granulosus calcyphosin protein 0.0055 0.0148 0.0145
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0112 0.0296
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0223 0.0676
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0892
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0086 0.0304 0.0288
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0119 0.0355
Trypanosoma brucei calpain-like protein, putative 0.0286 0.1315 0.4027
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0068 0.0214 0.0212
Trichomonas vaginalis calcineurin B subunit, putative 0.0048 0.0112 0.0333
Loa Loa (eye worm) hypothetical protein 0.2006 1 1
Schistosoma mansoni hypothetical protein 0.007 0.0224 0.0222
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0086 0.0304 0.0892
Trypanosoma cruzi centrin, putative 0.0103 0.039 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0016 0.0037
Trypanosoma brucei hypothetical protein 0.0086 0.0304 0.0892
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Onchocerca volvulus 0.0106 0.0403 0.1778
Trypanosoma brucei centrin, putative 0.0048 0.0112 0.0296
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0092 0.009
Giardia lamblia Encystation-specific protease 0.0068 0.0214 0.0615
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.4027
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0074 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0068 0.0214 0.0212
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0091 0.0327 0.0311
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.0403 0.1233
Brugia malayi Cytochrome P450 family protein 0.003 0.002 0.0017
Toxoplasma gondii calmodulin, putative 0.0055 0.0148 0.0408
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0002 0.0002
Trichomonas vaginalis fk506-binding protein, putative 0.0029 0.0016 0.0037
Trypanosoma cruzi cysteine protease, putative 0.0084 0.0291 0.0275
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Echinococcus granulosus chromobox protein 1 0.0067 0.0209 0.0207
Echinococcus granulosus EF HAND 1 calcium binding site 0.0048 0.0112 0.0109
Brugia malayi beta-lactamase 0.007 0.0223 0.022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Echinococcus granulosus neurocalcin 0.0048 0.0112 0.0109
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0096 0.0356 0.0356
Onchocerca volvulus 0.0048 0.0112 0.0485
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0029 0.0016 0.5
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0106 0.0403 0.4203
Schistosoma mansoni hypothetical protein 0.0032 0.003 0.0027
Plasmodium vivax vivapain-2 0.0106 0.0403 0.298
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0084 0.0291 0.0289
Loa Loa (eye worm) hypothetical protein 0.0048 0.0112 0.0112
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0219 0.0216
Loa Loa (eye worm) FKBP5 protein 0.0211 0.0937 0.0937
Trichomonas vaginalis calmodulin, putative 0.0048 0.0112 0.0333
Loa Loa (eye worm) hypothetical protein 0.007 0.0223 0.0223
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0029 0.0016 0.0014
Leishmania major calmodulin-like protein 0.0048 0.0112 0.0296
Entamoeba histolytica cysteine protease, putative 0.0068 0.0214 0.2155
Echinococcus multilocularis protein patched 0.0041 0.0078 0.0076
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0086 0.0304 0.0288
Toxoplasma gondii EFHC1, putative 0.0048 0.0112 0.0296
Loa Loa (eye worm) hypothetical protein 0.0055 0.0148 0.0148
Trichomonas vaginalis calpain, putative 0.0086 0.0304 0.0926
Trypanosoma cruzi caltractin, putative 0.0048 0.0112 0.0096
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0211 0.0937 0.2855
Schistosoma mansoni ef hand domain family member A2 0.0048 0.0112 0.0109
Echinococcus multilocularis geminin 0.0179 0.0771 0.0769
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0223 0.022
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0304 0.0288
Giardia lamblia Cysteine protease 0.0068 0.0214 0.0615
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0211 0.0937 1
Mycobacterium tuberculosis Conserved protein 0.007 0.0223 0.0979
Echinococcus multilocularis EF hand domain containing family member A2 0.0048 0.0112 0.0109
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0086 0.0304 0.0926
Trichomonas vaginalis calcium binding protein, putative 0.0048 0.0112 0.0333
Brugia malayi chromobox protein homolog 3 0.0038 0.006 0.0057
Giardia lamblia Cathepsin L precursor 0.0068 0.0214 0.0615
Entamoeba histolytica calcium binding family protein 0.0048 0.0112 0.1038
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0219 0.0216
Echinococcus granulosus cysteine protease 0.0084 0.0291 0.0289
Loa Loa (eye worm) calpain family protein 1 0.0559 0.269 0.269
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0029 0.0016 0.0016
Schistosoma mansoni immunophilin 0.0211 0.0937 0.0935
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.003 0.0027
Brugia malayi beta-lactamase family protein 0.007 0.0223 0.022
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0068 0.0214 0.2155
Loa Loa (eye worm) hypothetical protein 0.0038 0.006 0.006
Plasmodium vivax hypothetical protein, conserved 0.007 0.0223 0.1592
Trypanosoma cruzi cruzipain precursor, putative 0.0106 0.0403 0.0388
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0029 0.0016 0.0014
Giardia lamblia Cathepsin B precursor 0.0668 0.3241 1
Echinococcus multilocularis chromobox protein 1 0.0067 0.0209 0.0207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0214 0.065
Giardia lamblia Hypothetical protein 0.0068 0.0214 0.0615
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.1315 0.4027
Plasmodium falciparum serine repeat antigen 5 0.0068 0.0214 0.2155
Loa Loa (eye worm) hypothetical protein 0.0182 0.079 0.079
Schistosoma mansoni cathepsin F (C01 family) 0.0106 0.0403 0.0401
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0403 0.0388
Giardia lamblia Cysteine protease 0.0068 0.0214 0.0615
Schistosoma mansoni reticulocalbin 0.0048 0.0112 0.0109
Entamoeba histolytica cysteine protease, putative 0.0084 0.0291 0.2985
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0068 0.0214 0.065
Echinococcus granulosus cathepsin b 0.2006 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0106 0.0403 0.1233
Trichomonas vaginalis calpain, putative 0.0086 0.0304 0.0926
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.1315 0.1301
Echinococcus granulosus cathepsin l cysteine peptidase 0.0106 0.0403 0.0401
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2006 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0092 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Trypanosoma brucei calmodulin, putative 0.0048 0.0112 0.0296
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0055 0.0148 0.1014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Trichomonas vaginalis centrin, putative 0.0055 0.0148 0.0444
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0048 0.0112 0.0096
Onchocerca volvulus Cathepsin L homolog 0.0106 0.0403 0.1778
Loa Loa (eye worm) hypothetical protein 0.0559 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.0091 0.0327 0.0327
Echinococcus granulosus expressed conserved protein 0.0091 0.0326 0.0324
Echinococcus multilocularis neuronal calcium sensor 0.0048 0.0112 0.0109
Mycobacterium leprae Probable lipase LipE 0.007 0.0223 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0119 0.0319
Echinococcus multilocularis Calcium binding protein 0.0055 0.0148 0.0145
Plasmodium falciparum serine repeat antigen 3 0.0068 0.0214 0.2155
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0119 0.0319
Brugia malayi calcium-binding protein 0.0048 0.0112 0.0109
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0106 0.0403 0.0403
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0182 0.018
Echinococcus multilocularis calpain family protein 1, d 0.0559 0.269 0.2689
Entamoeba histolytica hypothetical protein 0.007 0.0224 0.2258
Trypanosoma brucei calpain-like protein, putative 0.0286 0.1315 0.4027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Mycobacterium ulcerans beta-lactamase 0.007 0.0223 0.2245
Schistosoma mansoni calpain C (C02 family) 0.0286 0.1315 0.1313
Echinococcus multilocularis calcyphosin protein 0.0055 0.0148 0.0145
Loa Loa (eye worm) hypothetical protein 0.0055 0.0148 0.0148
Brugia malayi Cathepsin L-like precursor 0.0106 0.0403 0.0401
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0209 0.0633
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0068 0.0214 0.065
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0068 0.0214 0.065
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.003 0.0027
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0049 0.0115 0.0762
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0048 0.0112 0.0109
Brugia malayi hypothetical protein 0.007 0.0224 0.0222
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0119 0.0103
Schistosoma mansoni fk506 binding protein 0.0029 0.0016 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0403 0.12
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0807 0.3944 0.3942
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0068 0.0214 0.1528
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0211 0.0937 0.0935
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0119 0.0119
Giardia lamblia Calmodulin 0.0055 0.0148 0.0408

Activities

Activity type Activity value Assay description Source Reference
CC50 (ADMET) > 100 uM Cytotoxicity against in 2209-23 cells by WST assay ChEMBL. 17367121
EC50 (functional) = 1.37 uM Inhibition of HCV RNA replication in 2209-23 cells transfected with bicistronic HCV replicon ChEMBL. 17367121

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.