Detailed information for compound 51290

Basic information

Technical information
  • TDR Targets ID: 51290
  • Name: 5,6-dimethyl-2-[(E)-2-pyridin-3-ylethenyl]-1H -benzimidazole
  • MW: 249.31 | Formula: C16H15N3
  • H donors: 1 H acceptors: 2 LogP: 3.45 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc2[nH]c(nc2cc1C)/C=C/c1cccnc1
  • InChi: 1S/C16H15N3/c1-11-8-14-15(9-12(11)2)19-16(18-14)6-5-13-4-3-7-17-10-13/h3-10H,1-2H3,(H,18,19)/b6-5+
  • InChiKey: HBVOFLLJSMHEQA-AATRIKPKSA-N  


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Synonyms

  • 5,6-dimethyl-2-[(E)-2-(3-pyridyl)vinyl]-1H-benzimidazole
  • MLS001178515
  • SMR000477602
  • ZINC04661287
  • 5,6-dimethyl-2-[2-(3-pyridinyl)vinyl]-1H-benzimidazole

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0181 0.0553
Echinococcus granulosus cathepsin l1 0.0092 0.0387 0.0387
Schistosoma mansoni importin beta-1 0.0028 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0049 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.006 0.0225 0.0225
Entamoeba histolytica cysteine protease, putative 0.0108 0.0466 0.3333
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0271 0.0826
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0065 0.0251 0.0251
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0069 0.0069
Trypanosoma cruzi cysteine protease, putative 0.0085 0.035 0.035
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0108 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Brugia malayi Neuronal calcium sensor family protein 1 0.0056 0.0205 0.0205
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Echinococcus granulosus importin subunit beta 1 0.0028 0.0066 0.0066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.2029
Loa Loa (eye worm) EF hand family protein 0.0065 0.0251 0.0251
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0069 0.0271 0.0271
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0531 0.0531
Onchocerca volvulus 0.0108 0.0466 0.1372
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0108 0.0466 0.0466
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0378 0.0378
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0066 0.0066
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Entamoeba histolytica calpain family cysteine protease, putative 0.0126 0.0558 0.3989
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0108 0.0465 0.0465
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0021 0.0021
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0285 0.1284
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0108 0.0465 0.0465
Trypanosoma brucei antigen, putative 0.042 0.2029 0.6187
Mycobacterium tuberculosis Conserved protein 0.0072 0.0285 0.1284
Brugia malayi RNA, U transporter 1 0.008 0.0325 0.0325
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Entamoeba histolytica cysteine proteinase, putative 0.0085 0.035 0.2502
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0205 0.0624
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0069 0.0271 0.1936
Plasmodium falciparum serine repeat antigen 9 0.0069 0.0271 0.4853
Schistosoma mansoni ef hand domain family member A2 0.0065 0.0251 0.0251
Loa Loa (eye worm) cysteine protease 0.0108 0.0466 0.0466
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0285 0.0285
Plasmodium falciparum serine repeat antigen 4 0.0069 0.0271 0.4853
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Loa Loa (eye worm) fibroinase 0.0108 0.0466 0.0466
Brugia malayi MH2 domain containing protein 0.0024 0.0046 0.0046
Brugia malayi MH1 domain containing protein 0.0024 0.0046 0.0046
Toxoplasma gondii kringle domain-containing protein 0.0017 0.0011 0.0034
Entamoeba histolytica hypothetical protein 0.0069 0.0271 0.1936
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.0644 0.0644
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0069 0.0271 0.0826
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0181 0.0181
Plasmodium vivax serine-repeat antigen (SERA) 0.0069 0.0271 0.1335
Brugia malayi Cathepsin L-like precursor 0.0108 0.0466 0.0466
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0069 0.0069
Onchocerca volvulus 0.0072 0.0285 0.084
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0108 0.0465 0.0465
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0083 0.0083
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0182 0.0555
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0126 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0068 0.0266 0.0266
Plasmodium vivax unspecified product 0.0069 0.0271 0.1335
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0137 0.0418
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0085 0.035 0.035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Loa Loa (eye worm) acetyltransferase 0.0143 0.0644 0.0644
Plasmodium falciparum serine repeat antigen 6 0.0069 0.0271 0.4853
Loa Loa (eye worm) hypothetical protein 0.0179 0.0821 0.0821
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0126 0.0558 0.1702
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0108 0.0465 0.1419
Schistosoma mansoni hypothetical protein 0.0065 0.0251 0.0251
Entamoeba histolytica calmodulin, putative 0.0056 0.0205 0.1462
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0029
Giardia lamblia Programmed cell death protein-like protein 0.0056 0.0205 0.0624
Entamoeba histolytica cysteine protease, putative 0.0069 0.0271 0.1936
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0459 0.2224 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0069 0.0271 0.0271
Trichomonas vaginalis centrin, putative 0.0056 0.0205 0.0624
Loa Loa (eye worm) hypothetical protein 0.0031 0.0083 0.0083
Trichomonas vaginalis calmodulin-2, putative 0.0065 0.0251 0.0765
Schistosoma mansoni cathepsin F (C01 family) 0.0108 0.0466 0.0466
Mycobacterium ulcerans hypothetical protein 0.0072 0.0285 0.6135
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0069 0.0271 0.0826
Trichomonas vaginalis calcineurin B subunit, putative 0.0065 0.0251 0.0765
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0251
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0271 0.0826
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.0466 0.3333
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Echinococcus granulosus cathepsin L 0.0069 0.0271 0.0271
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0069 0.1487
Brugia malayi CHE-14 protein 0.0051 0.0181 0.0181
Leishmania major calmodulin, putative 0.0065 0.0251 0.0765
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0285 0.087
Echinococcus granulosus Calcium binding protein 0.0056 0.0205 0.0205
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2011 1 1
Entamoeba histolytica calmodulin, putative 0.0065 0.0251 0.1793
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0108 0.0465 0.1419
Echinococcus granulosus geminin 0.0337 0.1616 0.1616
Brugia malayi programmed cell death protein 6 0.0065 0.0251 0.0251
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0285 0.1284
Loa Loa (eye worm) hypothetical protein 0.0072 0.0285 0.0285
Trypanosoma brucei calpain-like protein, putative 0.042 0.2029 0.6187
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Trichomonas vaginalis calcium binding protein, putative 0.0065 0.0251 0.0765
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0108 0.0465 0.1419
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0251 0.1236
Echinococcus granulosus chromobox protein 1 0.007 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0065 0.0251 0.0251
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0271 0.0826
Trypanosoma cruzi major cysteine proteinase, putative 0.0069 0.0271 0.0271
Schistosoma mansoni myosin light chain 0.0056 0.0205 0.0205
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0126 0.0558 0.0558
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0182 0.0182
Echinococcus granulosus tumor protein p63 0.0408 0.197 0.197
Entamoeba histolytica protein kinase, putative 0.0294 0.1399 1
Loa Loa (eye worm) calpain family protein 1 0.1113 0.5503 0.5503
Entamoeba histolytica cysteine protease, putative 0.0069 0.0271 0.1936
Schistosoma mansoni calmodulin-related 0.0056 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Plasmodium falciparum calpain 0.0126 0.0558 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0221 0.0674
Echinococcus multilocularis cathepsin L cysteine protease 0.0108 0.0466 0.0466
Echinococcus granulosus muscleblind protein 0.018 0.0829 0.0829
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0053 0.0053
Giardia lamblia Cathepsin L precursor 0.0069 0.0271 0.0826
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0069 0.0271 0.1335
Leishmania major hypothetical protein, conserved 0.0065 0.0251 0.0765
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0378 0.0378
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0378 0.0378
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0182 0.0182
Schistosoma mansoni neuronal calcium sensor 0.0065 0.0251 0.0251
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0065 0.0251 0.0251
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0021 0.0021
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0521 0.3726
Toxoplasma gondii centrin 0.0065 0.0251 0.0765
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1178 0.5828 0.5828
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0046 0.0046
Schistosoma mansoni calpain (C02 family) 0.042 0.2029 0.2029
Trichomonas vaginalis calpain, putative 0.0126 0.0558 0.1702
Toxoplasma gondii cathepsin CPC2 0.0069 0.0271 0.0826
Loa Loa (eye worm) hypothetical protein 0.0051 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0182 0.084 0.084
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0015 0 0.5
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0069 0.0271 0.4853
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0053 0.0161
Giardia lamblia Cysteine protease 0.0069 0.0271 0.0826
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Trichomonas vaginalis centrin, putative 0.0065 0.0251 0.0765
Brugia malayi Cathepsin L-like precursor 0.0108 0.0466 0.0466
Echinococcus multilocularis cathepsin L 0.0069 0.0271 0.0271
Onchocerca volvulus 0.0065 0.0251 0.0738
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0069 0.0271 0.0826
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0271 0.0826
Echinococcus granulosus neurocalcin 0.0065 0.0251 0.0251
Trypanosoma cruzi caltractin, putative 0.0065 0.0251 0.0251
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Echinococcus granulosus EF HAND 1 calcium binding site 0.0065 0.0251 0.0251
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0181 0.0181
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.042 0.2029 0.2029
Loa Loa (eye worm) myosin regulatory light chain 1 0.0056 0.0205 0.0205
Schistosoma mansoni hypothetical protein 0.0065 0.0251 0.0251
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Toxoplasma gondii centrin, putative 0.0065 0.0251 0.0765
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0053 0.0946
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0069 0.0311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.2029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0085 0.035 0.1068
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0119 0.0854
Entamoeba histolytica hypothetical protein 0.0043 0.0143 0.1025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0108 0.0466 0.1422
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0271 0.0826
Loa Loa (eye worm) cathepsin B 0.067 0.328 0.328
Trypanosoma cruzi kinesin, putative 0.0294 0.1397 0.1397
Schistosoma mansoni immunophilin 0.0108 0.0465 0.0465
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0182 0.0555
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0069 0.0271 0.4853
Plasmodium falciparum cysteine proteinase falcipain 1 0.0085 0.035 0.6274
Echinococcus granulosus cathepsin b 0.2011 1 1
Loa Loa (eye worm) calmodulin-like protein 0.0065 0.0251 0.0251
Brugia malayi Muscleblind-like protein 0.018 0.0829 0.0829
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0276 0.0276
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0108 0.0465 0.0465
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0182 0.0182
Trypanosoma brucei calpain-like protein, putative 0.042 0.2029 0.6187
Loa Loa (eye worm) hypothetical protein 0.0099 0.0423 0.0423
Brugia malayi cathepsin Z-like cysteine proteinase 0.0069 0.0271 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0069 0.0271 0.0826
Schistosoma mansoni smad1 5 8 and 0.0024 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Trypanosoma brucei centrin, putative 0.0065 0.0251 0.0765
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Leishmania major calpain family cysteine protease-like protein 0.0126 0.0558 0.1702
Loa Loa (eye worm) hypothetical protein 0.0029 0.0069 0.0069
Schistosoma mansoni myosin regulatory light chain 0.0056 0.0205 0.0205
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0069 0.1487
Plasmodium vivax calpain, putative 0.042 0.2029 1
Echinococcus multilocularis calpain family protein 1, d 0.082 0.4031 0.4031
Leishmania major cysteine peptidase A (CPA) 0.0108 0.0466 0.1422
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0069 0.0271 0.0271
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0069 0.0271 0.0826
Trypanosoma brucei centrin, putative 0.0065 0.0251 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Loa Loa (eye worm) hypothetical protein 0.0987 0.487 0.487
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0182 0.0182
Schistosoma mansoni chromobox protein 0.007 0.0276 0.0276
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0108 0.0465 0.8336
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0083 0.0083
Schistosoma mansoni centrin-related 0.0065 0.0251 0.0251
Giardia lamblia Cathepsin L precursor 0.0069 0.0271 0.0826
Entamoeba histolytica hypothetical protein 0.0043 0.0143 0.1025
Toxoplasma gondii cathepsin B 0.067 0.328 1
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0108 0.0465 0.0465
Leishmania major centrin, putative,caltractin, putative 0.0065 0.0251 0.0765
Brugia malayi hypothetical protein 0.0016 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0069 0.0271 0.0826
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Schistosoma mansoni cathepsin B (C01 family) 0.0069 0.0271 0.0271
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0182 0.0182
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0221 0.4751
Plasmodium falciparum centrin-1 0.0065 0.0251 0.4495
Toxoplasma gondii centrin family protein 0.0056 0.0205 0.0624
Schistosoma mansoni ran 0.0021 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0251 0.0765
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0069 0.1487
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Trypanosoma brucei calpain-like protein, putative 0.042 0.2029 0.6187
Entamoeba histolytica calmodulin, putative 0.0065 0.0251 0.1793
Trypanosoma cruzi calmodulin, putative 0.0065 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0108 0.0466 0.0466
Echinococcus multilocularis calpain A 0.1178 0.5828 0.5828
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0285 0.0285
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0033 0.0707
Entamoeba histolytica hypothetical protein 0.0043 0.0143 0.1025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.0644 0.0644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0092 0.0387 0.118
Entamoeba histolytica cysteine protease, putative 0.0069 0.0271 0.1936
Giardia lamblia Cathepsin L precursor 0.0069 0.0271 0.0826
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0137 0.0404
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Loa Loa (eye worm) ctsf protein 0.0108 0.0466 0.0466
Echinococcus granulosus expressed conserved protein 0.0112 0.0485 0.0485
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0069 0.0271 0.0826
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0624 0.0624
Toxoplasma gondii cathepsin CPL 0.0108 0.0466 0.1422
Schistosoma mansoni hypothetical protein 0.0337 0.1616 0.1616
Schistosoma mansoni hypothetical protein 0.0126 0.0558 0.0558
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0027 0.0122
Plasmodium vivax vivapain-2 0.0108 0.0466 0.2298
Entamoeba histolytica grainin, putative 0.0065 0.0251 0.1793
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0266 0.0266
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0065 0.0251 0.0765
Loa Loa (eye worm) hypothetical protein 0.0069 0.0271 0.0271
Brugia malayi Cathepsin L-like precursor 0.0092 0.0387 0.0387
Brugia malayi beta-lactamase family protein 0.0072 0.0285 0.0285
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0056 0.0205 0.1008
Echinococcus multilocularis neurocalcin 0.0065 0.0251 0.0251
Giardia lamblia Calmodulin 0.0056 0.0205 0.0624
Toxoplasma gondii preprocathepsin c precursor, putative 0.0069 0.0271 0.0826
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0033 0.059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0378 0.0378
Brugia malayi Cathepsin L-like precursor 0.0108 0.0466 0.0466
Schistosoma mansoni neuronal calcium sensor 0.0065 0.0251 0.0251
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0065 0.0253 0.0253
Plasmodium falciparum centrin-4 0.0056 0.0205 0.3664
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0137 0.0418
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0056 0.0205 0.0602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.035 0.1068
Schistosoma mansoni mitochondrial solute carrier 0.0065 0.0251 0.0251
Echinococcus granulosus Myosin regulatory light chain 0.0056 0.0205 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0558 0.1702
Trichomonas vaginalis esterase, putative 0.0072 0.0285 0.087
Onchocerca volvulus 0.0072 0.0285 0.084
Brugia malayi calcium-binding protein 0.0065 0.0251 0.0251
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0137 0.0418
Schistosoma mansoni cathepsin C 0.0069 0.0271 0.0271
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0066 0.0201
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0182 0.0555
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0056 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0062 0.0239 0.0239
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0182 0.0555
Schistosoma mansoni smad 0.0024 0.0046 0.0046
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0069 0.0271 0.0271
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0069 0.0271 0.0271
Plasmodium vivax unspecified product 0.0085 0.035 0.1725
Schistosoma mansoni calpain-2 (C02 family) 0.0126 0.0558 0.0558
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0029 0.0143
Brugia malayi N-terminal motif family protein 0.0179 0.0821 0.0821
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Leishmania major phospholipase c-like protein 0.0065 0.0251 0.0765
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0021 0.0021
Trypanosoma cruzi kinesin, putative 0.0294 0.1397 0.1397
Mycobacterium ulcerans beta-lactamase 0.0072 0.0285 0.6135
Loa Loa (eye worm) hypothetical protein 0.0072 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0029 0.0069 0.0069
Echinococcus granulosus calpain A 0.042 0.2029 0.2029
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0205 0.0205
Trypanosoma brucei calpain, putative 0.0126 0.0558 0.1702
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1113 0.5503 0.5503
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0221 0.0221
Onchocerca volvulus 0.0056 0.0205 0.0602
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0029 0.0029
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0122 0.0373
Leishmania major fk506-binding protein 1-like protein 0.0108 0.0465 0.1419
Loa Loa (eye worm) FKBP5 protein 0.0108 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0072 0.0285 0.0285
Echinococcus multilocularis hypothetical protein 0.042 0.2029 0.2029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0126 0.0558 0.0558
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0069 0.0271 0.0271
Trypanosoma brucei Calpain-like protein CALP1.3 0.0126 0.0558 0.1702
Plasmodium vivax unspecified product 0.0016 0.0005 0.0025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0069 0.0271 0.0271
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0039 0.012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0271 0.0271
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0137 0.0418
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.6187
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0069 0.0271 0.0826
Echinococcus multilocularis calmodulin 0.0065 0.0251 0.0251
Leishmania major calcineurin B subunit, putative 0.0065 0.0251 0.0765
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0069 0.0211
Echinococcus granulosus cathepsin l cysteine peptidase 0.0108 0.0466 0.0466
Toxoplasma gondii EF hand domain-containing protein 0.0065 0.0251 0.0765
Schistosoma mansoni hypothetical protein 0.0031 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0031 0.0083 0.0083
Loa Loa (eye worm) myosin Light Chain family member 0.0056 0.0205 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.6187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Plasmodium vivax importin-beta 2, putative 0.0028 0.0066 0.0325
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Schistosoma mansoni myosin regulatory light chain 0.0056 0.0205 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Schistosoma mansoni hypothetical protein 0.0049 0.0172 0.0172
Schistosoma mansoni rab 0.0065 0.0251 0.0251
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0108 0.0465 0.0465
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0108 0.0465 0.0465
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0182 0.0182
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0285 0.0285
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2011 1 1
Schistosoma mansoni calpain-7 (C02 family) 0.042 0.2029 0.2029
Loa Loa (eye worm) hypothetical protein 0.0056 0.0205 0.0205
Leishmania major calmodulin-like protein 0.0065 0.0251 0.0765
Onchocerca volvulus Cathepsin L homolog 0.0069 0.0271 0.0797
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0126 0.0558 0.1702
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0285 0.087
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0015 0 0.5
Loa Loa (eye worm) hypothetical protein 0.082 0.4031 0.4031
Schistosoma mansoni patched 1 0.0051 0.0181 0.0181
Brugia malayi EF hand family protein 0.0065 0.0251 0.0251
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0039 0.012
Toxoplasma gondii EF hand domain-containing protein 0.0056 0.0205 0.0624
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.4831 0.4831
Echinococcus multilocularis neuropeptide receptor A26 0.0467 0.2264 0.2264
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0423 0.0423
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0069 0.0211
Echinococcus multilocularis tumor protein p63 0.0408 0.197 0.197
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0069 0.0271 0.0271
Schistosoma mansoni neuronal calcium sensor 0.0065 0.0251 0.0251
Trypanosoma cruzi conserved protein 0.0126 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0093 0.0391 0.0391
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0092 0.0387 0.118
Loa Loa (eye worm) hypothetical protein 0.0028 0.0066 0.0066
Toxoplasma gondii calcium-dependent protein kinase 0.0065 0.0253 0.0772
Trichomonas vaginalis immunophilin, putative 0.0108 0.0465 0.1419
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.0466 0.3333
Loa Loa (eye worm) hypothetical protein 0.0029 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0108 0.0466 0.1422
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Giardia lamblia Cathepsin B precursor 0.0069 0.0271 0.0826
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0285 0.1284
Loa Loa (eye worm) MH2 domain-containing protein 0.0351 0.1685 0.1685
Trypanosoma cruzi cysteine proteinase, putative 0.0085 0.035 0.035
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0143 0.0143
Leishmania major peptidylprolyl isomerase-like protein 0.0108 0.0465 0.1419
Plasmodium falciparum serine repeat antigen 2 0.0069 0.0271 0.4853
Echinococcus multilocularis fk506 binding protein 0.0108 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0031 0.008 0.008
Trichomonas vaginalis centrin, putative 0.0056 0.0205 0.0624
Trichomonas vaginalis calcium binding protein, putative 0.0065 0.0251 0.0765
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0285 0.6135
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0225 0.0225
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0108 0.0465 1
Echinococcus granulosus smad 0.0024 0.0046 0.0046
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0126 0.0558 0.0558
Brugia malayi cathepsin F-like cysteine proteinase 0.0016 0.0005 0.0005
Giardia lamblia Cysteine protease 0.0069 0.0271 0.0826
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Giardia lamblia Encystation-specific protease 0.0069 0.0271 0.0826
Echinococcus multilocularis neuronal calcium sensor 0.0065 0.0251 0.0251
Echinococcus multilocularis calpain 7 (C02 family) 0.042 0.2029 0.2029
Leishmania major GTP-binding protein, putative 0.0021 0.0029 0.0088
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0069 0.0311
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0221 0.4751
Onchocerca volvulus 0.0108 0.0466 0.1372
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0285 0.0285
Brugia malayi fibroinase precursor 0.0069 0.0271 0.0271
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0521 0.0521
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0126 0.0558 0.1702
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.042 0.2029 0.2029
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0046 0.0046
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0065 0.0253 0.0772
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0066 0.0201
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0069 0.1487
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0069 0.0271 0.0826
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0083 0.0083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0083 0.0083
Leishmania major hypothetical protein, conserved 0.0072 0.0285 0.087
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0271 0.0826
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.035 0.1068
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0069 0.0271 0.4853
Trypanosoma brucei cysteine peptidase, putative 0.0126 0.0558 0.1702
Echinococcus granulosus programmed cell death protein 6 0.0056 0.0205 0.0205
Trypanosoma brucei caltractin, putative 0.0121 0.053 0.1615
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Onchocerca volvulus Cathepsin L homolog 0.0108 0.0466 0.1372
Echinococcus granulosus neuropeptide receptor A26 0.0467 0.2264 0.2264
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0143 0.0143
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0011 0.0011
Echinococcus granulosus cathepsin L cysteine protease 0.0085 0.035 0.035
Echinococcus multilocularis calbindin 32 0.0065 0.0251 0.0251
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0285 0.087
Giardia lamblia Cathepsin B precursor 0.0069 0.0271 0.0826
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0033 0.0162
Entamoeba histolytica hypothetical protein 0.0043 0.0143 0.1025
Schistosoma mansoni hypothetical protein 0.0049 0.0172 0.0172
Echinococcus multilocularis neuropeptide s receptor 0.0467 0.2264 0.2264
Leishmania major calmodulin, putative 0.0065 0.0251 0.0765
Loa Loa (eye worm) Smad1 0.0024 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0126 0.0558 0.1702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0039 0.012
Schistosoma mansoni hypothetical protein 0.0049 0.0172 0.0172
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0083 0.0083
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0085 0.035 0.035
Brugia malayi RasGEF domain containing protein 0.0058 0.0215 0.0215
Entamoeba histolytica cysteine proteinase, putative 0.0085 0.035 0.2502
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0285 0.087
Leishmania major hypothetical protein, conserved 0.0126 0.0558 0.1702
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1178 0.5828 0.5828
Loa Loa (eye worm) hypothetical protein 0.0119 0.0521 0.0521
Echinococcus granulosus programmed cell death protein 0.0121 0.053 0.053
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Entamoeba histolytica Ran family GTPase 0.0021 0.0029 0.0207
Trypanosoma brucei protein kinase, putative 0.0051 0.0182 0.0555
Trypanosoma brucei calpain, putative 0.0126 0.0558 0.1702
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0069 0.0271 0.1335
Echinococcus granulosus centrin 2 0.0065 0.0251 0.0251
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0182 0.0555
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0069 0.1487
Echinococcus multilocularis cysteine protease 0.0108 0.0466 0.0466
Brugia malayi Smad1 0.0024 0.0046 0.0046
Toxoplasma gondii troponin c, isotype gamma, putative 0.0065 0.0251 0.0765
Plasmodium falciparum importin beta, putative 0.0028 0.0066 0.1182
Trypanosoma cruzi calmodulin, putative 0.0065 0.0251 0.0251
Trichomonas vaginalis calcium binding proteins, putative 0.0065 0.0251 0.0765
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0137 0.0418
Entamoeba histolytica grainin 2 0.0121 0.053 0.3785
Echinococcus granulosus neuronal calcium sensor 0.0065 0.0251 0.0251
Trypanosoma cruzi calpain cysteine peptidase, putative 0.042 0.2029 0.2029
Onchocerca volvulus 0.0108 0.0466 0.1372
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0221 0.0221
Brugia malayi hypothetical protein 0.0182 0.084 0.084
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0181 0.0181
Echinococcus granulosus cysteine protease 0.0085 0.035 0.035
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.053 0.1615
Loa Loa (eye worm) calpain family protein 1 0.082 0.4031 0.4031
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0108 0.0466 0.0466
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0423 0.0423
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0126 0.0558 0.0558
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0065 0.0251 0.0251
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0378 0.0378
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0066 0.0201
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2011 1 1
Trypanosoma cruzi calmodulin, putative 0.0065 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Loa Loa (eye worm) calpain D 0.0126 0.0558 0.0558
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0069 0.0271 0.1335
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0182 0.0182
Brugia malayi chromobox protein homolog 3 0.0039 0.0122 0.0122
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0285 0.6135
Trypanosoma brucei hypothetical protein, conserved 0.0065 0.0251 0.0765
Echinococcus granulosus EF hand domain containing family member A2 0.0065 0.0251 0.0251
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0285 0.1284
Onchocerca volvulus Cathepsin L homolog 0.0108 0.0466 0.1372
Schistosoma mansoni hypothetical protein 0.0299 0.1423 0.1423
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0039 0.0039
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0069 0.0271 0.1335
Schistosoma mansoni reticulocalbin 0.0065 0.0251 0.0251
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Echinococcus multilocularis EF hand domain containing family member A2 0.0065 0.0251 0.0251
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0021 0.0065
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0033 1
Giardia lamblia Cathepsin L-like protease 0.0069 0.0271 0.0826
Leishmania major hypothetical protein, conserved 0.0017 0.0011 0.0034
Toxoplasma gondii cathepsin CPC1 0.0069 0.0271 0.0826
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.067 0.328 1
Schistosoma mansoni calpain C (C02 family) 0.042 0.2029 0.2029
Entamoeba histolytica cysteine proteinase, putative 0.0085 0.035 0.2502
Loa Loa (eye worm) hypothetical protein 0.0108 0.0466 0.0466
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.0644 0.0644
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0378 0.0378
Onchocerca volvulus 0.0108 0.0466 0.1372
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0126 0.0558 0.0558
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0521 0.0521
Brugia malayi cathepsin F-like cysteine proteinase 0.0069 0.0271 0.0271
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0065 0.0251 0.0765
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0069 0.0271 0.0271
Trypanosoma brucei hypothetical protein 0.0126 0.0558 0.1702
Entamoeba histolytica hypothetical protein 0.0023 0.0039 0.0282
Echinococcus multilocularis cathepsin b 0.2011 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0069 0.0271 0.0826
Trypanosoma cruzi cysteine peptidase, putative 0.0085 0.035 0.035
Echinococcus granulosus GPCR family 2 0.0031 0.0083 0.0083
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0108 0.0466 0.8357
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0285 0.0285
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0069 0.0271 0.1335
Trichomonas vaginalis chromobox protein, putative 0.007 0.0276 0.0843
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.2029
Onchocerca volvulus 0.0693 0.3399 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0271 0.0826
Loa Loa (eye worm) transcription factor SMAD2 0.0351 0.1685 0.1685
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0119 0.2141
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0083 0.0083
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0137 0.0676
Mycobacterium tuberculosis Conserved protein 0.0072 0.0285 0.1284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0271 0.0826
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0137 0.0418
Echinococcus multilocularis programmed cell death protein 6 0.0056 0.0205 0.0205
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0092 0.0387 0.0387
Giardia lamblia Cathepsin B precursor 0.067 0.328 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0046 0.0046
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0029
Brugia malayi Papain family cysteine protease containing protein 0.0069 0.0271 0.0271
Mycobacterium ulcerans lipase LipD 0.0072 0.0285 0.6135
Echinococcus multilocularis protein dispatched 1 0.0058 0.0217 0.0217
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0011 0.0011
Plasmodium falciparum serine repeat antigen 1 0.0069 0.0271 0.4853
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.1423 0.1423
Trypanosoma brucei Calpain-like protein 1.2 0.0126 0.0558 0.1702
Brugia malayi Probable myosin regulatory light chain 0.0056 0.0205 0.0205
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0285 0.1407
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Giardia lamblia Hypothetical protein 0.0065 0.0251 0.0765
Echinococcus granulosus cathepsin l1 0.0108 0.0466 0.0466
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0108 0.0466 0.0466
Entamoeba histolytica hypothetical protein, conserved 0.0065 0.0251 0.1793
Leishmania major calmodulin-like protein 0.0065 0.0251 0.0765
Echinococcus multilocularis calumenin 0.0065 0.0251 0.0251
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0182 0.0182
Giardia lamblia Cathepsin B precursor 0.0069 0.0271 0.0826
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0221 0.0994
Echinococcus multilocularis muscleblind protein 0.018 0.0829 0.0829
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0108 0.0465 0.1419
Plasmodium vivax vivapain-3 0.0085 0.035 0.1725
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0027 0.0122
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0285 0.087
Brugia malayi calpain 5 0.0294 0.1397 0.1397
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0021 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0069 0.0494
Echinococcus multilocularis cathepsin L 0.0085 0.035 0.035
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0046 0.0046
Echinococcus multilocularis Myosin regulatory light chain 0.0056 0.0205 0.0205
Trichomonas vaginalis hypothetical protein 0.0126 0.0558 0.1702
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0069 0.0494
Echinococcus multilocularis smad 0.0024 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0122 0.0373
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Loa Loa (eye worm) hypothetical protein 0.018 0.0829 0.0829
Brugia malayi Papain family cysteine protease containing protein 0.0069 0.0271 0.0271
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1178 0.5828 0.5828
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0069 0.0211
Echinococcus multilocularis expressed conserved protein 0.0112 0.0485 0.0485
Brugia malayi EF hand family protein 0.0065 0.0251 0.0251
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0046 0.0046
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0065 0.0251 0.0251
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0119 0.0364
Brugia malayi Heterochromatin protein 1 0.007 0.0276 0.0276
Schistosoma mansoni smad1 5 8 and 0.0024 0.0046 0.0046
Echinococcus multilocularis Smad4 0.0024 0.0046 0.0046
Entamoeba histolytica cysteine protease, putative 0.0069 0.0271 0.1936
Schistosoma mansoni centrin 0.0065 0.0251 0.0251
Echinococcus granulosus calbindin 32 0.0065 0.0251 0.0251
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0285 0.0285
Echinococcus multilocularis calcium uptake protein 1 0.0065 0.0251 0.0251
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0029 0.0029
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0065 0.0253 0.0253
Leishmania major centrin, putative 0.0065 0.0251 0.0765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0085 0.035 0.1068
Schistosoma mansoni calpain-7 (C02 family) 0.042 0.2029 0.2029
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0069 0.0271 0.0826
Echinococcus granulosus calcium uptake protein 1 0.0065 0.0251 0.0251
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0027 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0251 0.0765
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0021 0.0021
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0029 0.0088
Giardia lamblia Cathepsin B precursor 0.067 0.328 1
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.042 0.2029 0.2029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0126 0.0558 0.0558
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0021 0.0065
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Trypanosoma brucei calmodulin, putative 0.0065 0.0251 0.0765
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Leishmania major programmed cell death 6 protein-like protein 0.0065 0.0251 0.0765
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0069 0.0271 0.0271
Leishmania major hypothetical protein, conserved 0.0025 0.0053 0.0161
Echinococcus granulosus calmodulin 0.0065 0.0251 0.0251
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0069 0.1487
Trichomonas vaginalis myosin light chain 1, putative 0.0065 0.0251 0.0765
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0108 0.0465 0.1419
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.067 0.328 0.328
Leishmania major hypothetical protein, unknown function 0.0126 0.0558 0.1702
Toxoplasma gondii calmodulin CAM1 0.0065 0.0251 0.0765
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0221 0.0221
Schistosoma mansoni cathepsin s 0.0016 0.0005 0.0005
Brugia malayi beta-lactamase 0.0072 0.0285 0.0285
Brugia malayi Cathepsin L-like precursor 0.0108 0.0466 0.0466
Trypanosoma cruzi cruzipain precursor, putative 0.0108 0.0466 0.0466
Leishmania major hypothetical protein, conserved 0.0065 0.0251 0.0765
Trichomonas vaginalis centrin, putative 0.0065 0.0251 0.0765
Loa Loa (eye worm) hypothetical protein 0.2011 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0182 0.0555
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Trypanosoma cruzi cruzipain precursor, putative 0.0016 0.0005 0.0005
Trypanosoma cruzi centrin, putative 0.0121 0.053 0.053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Echinococcus granulosus calpain 5 0.042 0.2029 0.2029
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0108 0.0465 0.0465
Echinococcus multilocularis programmed cell death protein 0.0121 0.053 0.053
Echinococcus multilocularis cathepsin b 0.2011 1 1
Echinococcus granulosus chromobox protein 1 0.007 0.0276 0.0276
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Entamoeba histolytica cysteine proteinase, putative 0.0092 0.0387 0.2767
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0108 0.0465 0.2293
Loa Loa (eye worm) hypothetical protein 0.0039 0.0122 0.0122
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.067 0.328 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0423 0.0423
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0069 0.0271 0.1335
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0005 0.0005
Echinococcus granulosus cathepsin L cysteine proteinase 0.0108 0.0466 0.0466
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0053 0.0053
Giardia lamblia Cathepsin L precursor 0.0069 0.0271 0.0826
Echinococcus granulosus cathepsin b 0.2011 1 1
Schistosoma mansoni cathepsin S (C01 family) 0.0069 0.0271 0.0271
Schistosoma mansoni cathepsin F (C01 family) 0.0092 0.0387 0.0387
Trypanosoma cruzi centrin, putative 0.0121 0.053 0.053
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1178 0.5828 0.5828
Brugia malayi Cathepsin L-like cysteine proteinase 0.0092 0.0387 0.0387
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0069 0.0271 0.1335
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.042 0.2029 0.2029
Schistosoma mansoni immunophilin 0.0093 0.0391 0.0391
Giardia lamblia Cathepsin B precursor 0.067 0.328 1
Brugia malayi hypothetical protein 0.0025 0.0053 0.0053
Giardia lamblia Cathepsin L precursor 0.0069 0.0271 0.0826
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Entamoeba histolytica cysteine proteinase 1, putative 0.0085 0.035 0.2502
Trichomonas vaginalis calcineurin B subunit, putative 0.0065 0.0251 0.0765
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0069 0.0271 0.0271
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0108 0.0465 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Echinococcus multilocularis tissue type plasminogen activator 0.0017 0.0011 0.0011
Loa Loa (eye worm) beta-lactamase 0.0072 0.0285 0.0285
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0016 0.0005 0.0005
Brugia malayi cathepsin L-like cysteine proteinase 0.0069 0.0271 0.0271
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0085 0.035 0.035
Onchocerca volvulus 0.0056 0.0205 0.0602
Loa Loa (eye worm) hypothetical protein 0.1113 0.5503 0.5503
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0065 0.0251 0.0251
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Mycobacterium tuberculosis Conserved protein 0.0072 0.0285 0.1284
Loa Loa (eye worm) calpain 5 0.0294 0.1397 0.1397
Schistosoma mansoni hypothetical protein 0.0068 0.0266 0.0266
Trichomonas vaginalis calcium binding protein, putative 0.0065 0.0251 0.0765
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0065 0.0251 0.0765
Trichomonas vaginalis calcium binding protein, putative 0.0056 0.0205 0.0624
Brugia malayi MH1 domain containing protein 0.0024 0.0046 0.0046
Echinococcus multilocularis protein patched 0.0051 0.0181 0.0181
Schistosoma mansoni Smad4 0.0024 0.0046 0.0046
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0285 0.0285
Echinococcus multilocularis programmed cell death protein 0.0121 0.053 0.053
Trichomonas vaginalis calmodulin, putative 0.0056 0.0205 0.0624
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0466 0.0466
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0021 0.0021
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0221 0.0221
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0069 0.0271 0.0271
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0056 0.0205 0.0624
Leishmania major centrin, putative 0.0065 0.0251 0.0765
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0069 0.0494
Schistosoma mansoni hypothetical protein 0.0031 0.0083 0.0083
Echinococcus multilocularis GPCR, family 2 0.0031 0.0083 0.0083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0378 0.0378
Trypanosoma cruzi cysteine proteinase, putative 0.0085 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0069 0.0271 0.0271
Brugia malayi Cathepsin L-like precursor 0.0092 0.0387 0.0387
Giardia lamblia Cysteine protease 0.0069 0.0271 0.0826
Schistosoma mansoni hypothetical protein 0.0043 0.0143 0.0143
Loa Loa (eye worm) calpain 0.042 0.2029 0.2029
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0182 0.0555
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0126 0.0558 0.1702
Plasmodium falciparum serine repeat antigen 8 0.0069 0.0271 0.4853
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0126 0.0558 0.1702
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0021 0.0021
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0521 0.0521
Plasmodium vivax vivapain-2 0.0108 0.0466 0.2298
Brugia malayi Importin beta-1 subunit 0.0028 0.0066 0.0066
Entamoeba histolytica calcium binding family protein 0.0065 0.0251 0.1793
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Trichomonas vaginalis calpain, putative 0.0126 0.0558 0.1702
Entamoeba histolytica cysteine protease, putative 0.0069 0.0271 0.1936
Echinococcus multilocularis calpain 0.042 0.2029 0.2029
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0221 0.4751
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2011 1 1
Schistosoma mansoni neuronal calcium sensor 0.0065 0.0251 0.0251
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0069 0.2423
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0285 0.087
Schistosoma mansoni immunophilin 0.0108 0.0465 0.0465
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0285 0.0285
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0065 0.0251 0.0251
Schistosoma mansoni calmodulin 0.0065 0.0251 0.0251
Plasmodium falciparum cysteine repeat modular protein 1 0.0017 0.0011 0.0197
Giardia lamblia Hypothetical protein 0.0069 0.0271 0.0826
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Entamoeba histolytica calcium-binding protein, putative 0.0065 0.0251 0.1793
Onchocerca volvulus 0.0108 0.0466 0.1372
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Leishmania major i/6 autoantigen-like protein 0.0065 0.0251 0.0765
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Onchocerca volvulus 0.0031 0.008 0.0235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Mycobacterium ulcerans hypothetical protein 0.0029 0.0069 0.1487
Toxoplasma gondii hypothetical protein 0.0126 0.0558 0.1702
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0088
Echinococcus granulosus calumenin 0.0065 0.0251 0.0251
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0069 0.1487
Plasmodium falciparum cysteine proteinase falcipain 3 0.0108 0.0466 0.8357
Toxoplasma gondii calcium binding protein precursor, putative 0.0056 0.0205 0.0624
Schistosoma mansoni ran 0.0021 0.0029 0.0029
Leishmania major protein kinase, putative 0.0065 0.0253 0.0772
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0029
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0108 0.0465 0.3325
Giardia lamblia Hypothetical protein 0.0069 0.0271 0.0826
Brugia malayi Papain family cysteine protease containing protein 0.0085 0.035 0.035
Schistosoma mansoni cathepsin F (C01 family) 0.0108 0.0466 0.0466
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Schistosoma mansoni Mername-AA248 (C02 family) 0.042 0.2029 0.2029
Loa Loa (eye worm) hypothetical protein 0.0072 0.0285 0.0285
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Entamoeba histolytica cysteine proteinase 2 0.0085 0.035 0.2502
Leishmania major kinesin, putative 0.0294 0.1397 0.4259
Trypanosoma brucei cysteine peptidase C (CPC) 0.067 0.328 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0033 0.0148
Brugia malayi Myosin regulatory light chain 1 0.0056 0.0205 0.0205
Trichomonas vaginalis caltractin, putative 0.0056 0.0205 0.0624
Trypanosoma cruzi I/6 autoantigen, putative 0.0065 0.0251 0.0251
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Echinococcus multilocularis muscleblind protein 1 0.018 0.0829 0.0829
Brugia malayi MH2 domain containing protein 0.0351 0.1685 0.1685
Onchocerca volvulus 0.006 0.0225 0.0662
Plasmodium vivax centrin-1, putative 0.0065 0.0251 0.1236
Onchocerca volvulus 0.0065 0.0251 0.0738
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0378 0.0378
Trypanosoma brucei Component of motile flagella 41 0.0065 0.0251 0.0765
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0137 0.0137
Schistosoma mansoni reticulocalbin 0.0065 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0069 0.0271 0.0271
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0069 0.0271 0.1335
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0182 0.0182
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0466 0.0466
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0777 0.0777
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.042 0.2029 0.6187
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0017 0.0011 0.0054
Onchocerca volvulus 0.0182 0.084 0.2471
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0056 0.0205 0.0602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Echinococcus multilocularis Calcium binding protein 0.0056 0.0205 0.0205
Trypanosoma brucei protein I/6 0.0065 0.0251 0.0765
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0046 0.0046
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0126 0.0558 0.0558
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.0821 0.2415
Echinococcus granulosus calpain 0.042 0.2029 0.2029
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0065 0.0198
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0053 0.0946
Leishmania major calpain protease-like protein 0.0126 0.0558 0.1702
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0093 0.0391 0.0391
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0085 0.035 0.035
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0108 0.0466 0.8357
Mycobacterium leprae Probable lipase LipE 0.0072 0.0285 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0069 0.0271 0.0271
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0021 0.0021
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0069 0.0271 0.1936
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0065 0.0251 0.0251
Echinococcus granulosus calpain 7 C02 family 0.042 0.2029 0.2029
Onchocerca volvulus 0.0017 0.0011 0.0032
Giardia lamblia Cathepsin L precursor 0.0069 0.0271 0.0826
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0053 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0271 0.0826
Echinococcus multilocularis cathepsin L cysteine protease 0.0108 0.0466 0.0466
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0108 0.0465 0.0465
Brugia malayi calpain 7 0.042 0.2029 0.2029
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0021 0.0382
Onchocerca volvulus Cathepsin F homolog 0.0108 0.0466 0.1372
Loa Loa (eye worm) hypothetical protein 0.0069 0.0271 0.0271
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0021 0.0096
Brugia malayi Papain family cysteine protease containing protein 0.0108 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0072 0.0285 0.0285
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0777 0.0777
Brugia malayi Protein kinase domain containing protein 0.0017 0.0011 0.0011
Echinococcus granulosus snurportin 1 0.0299 0.1423 0.1423
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0126 0.0558 0.1702
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0519
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0127 0.0561 0.171
Trypanosoma cruzi I/6 autoantigen, putative 0.0065 0.0251 0.0251
Onchocerca volvulus 0.0069 0.0271 0.0797
Onchocerca volvulus 0.0029 0.0069 0.0204
Schistosoma mansoni calmodulin 0.0065 0.0251 0.0251
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0126 0.0558 0.0558
Trichomonas vaginalis fk506-binding protein, putative 0.0108 0.0465 0.1419
Loa Loa (eye worm) hypothetical protein 0.0126 0.0558 0.0558
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0126 0.0558 0.1702
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0253 0.1248
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0182 0.0555
Trypanosoma brucei mitochondrial calcium uptake 1 0.0065 0.0251 0.0765
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0069 0.2423
Loa Loa (eye worm) hypothetical protein 0.0056 0.0205 0.0205
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0065 0.0251 0.0251
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Trypanosoma cruzi major cysteine proteinase, putative 0.0069 0.0271 0.0271
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0285 0.1284
Toxoplasma gondii ABC1 family protein 0.0072 0.0285 0.087
Loa Loa (eye worm) hypothetical protein 0.018 0.0829 0.0829
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0021 0.0065
Brugia malayi MAP kinase sur-1 0.0051 0.0182 0.0182
Entamoeba histolytica cysteine proteinase, putative 0.0085 0.035 0.2502
Giardia lamblia Cathepsin L-like protease 0.0069 0.0271 0.0826
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0285 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0021 0.0021
Brugia malayi beta-lactamase family protein 0.0072 0.0285 0.0285
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0021 0.0105
Brugia malayi Calmodulin-like protein 0.0065 0.0251 0.0251
Brugia malayi Cathepsin L-like precursor 0.0016 0.0005 0.0005
Trichomonas vaginalis ran, putative 0.0021 0.0029 0.0088
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0069 0.0271 0.1335
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0069 0.0271 0.1335
Trypanosoma brucei calpain-like protein, putative 0.042 0.2029 0.6187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0271 0.0826
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0182 0.0555
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Trypanosoma brucei kinesin, putative 0.0294 0.1397 0.4259
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0466 0.0466
Echinococcus granulosus Smad4 0.0024 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0092 0.0387 0.0387
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0021 0.0021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Giardia lamblia Cathepsin B precursor 0.0069 0.0271 0.0826
Loa Loa (eye worm) hypothetical protein 0.0092 0.0387 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0065 0.0198
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0221 0.0674
Plasmodium vivax vivapain-1 0.0085 0.035 0.1725
Trypanosoma brucei Calpain-like protein 1.1 0.0126 0.0558 0.1702
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.0466 0.1422
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0093 0.0391 0.0391
Schistosoma mansoni hypothetical protein 0.0031 0.0083 0.0083
Trichomonas vaginalis chromobox protein, putative 0.007 0.0276 0.0843
Brugia malayi Papain family cysteine protease containing protein 0.0069 0.0271 0.0271
Brugia malayi calpain D 0.0126 0.0558 0.0558
Echinococcus granulosus cathepsin L 0.0085 0.035 0.035
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0285 0.1284
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2011 1 1
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0285 0.1284
Trichomonas vaginalis caltractin, putative 0.0056 0.0205 0.0624
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0466 0.0466
Schistosoma mansoni calmodulin related calcium binding protein 0.0065 0.0251 0.0251
Leishmania major cathepsin L-like protease 0.0108 0.0466 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0466 0.1422
Schistosoma mansoni smad1 5 8 and 0.0024 0.0046 0.0046
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0108 0.0465 0.1419
Echinococcus multilocularis cysteine protease 0.0108 0.0466 0.0466
Giardia lamblia Cysteine protease 0.0069 0.0271 0.0826
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0021 0.0065
Brugia malayi MH2 domain containing protein 0.0024 0.0046 0.0046
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0108 0.0465 0.0465
Entamoeba histolytica calpain large subunit domain III containing protein 0.0294 0.1397 0.9983
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.6187
Onchocerca volvulus 0.0108 0.0466 0.1372
Echinococcus multilocularis chromobox protein 1 0.007 0.0276 0.0276
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0083 0.0083
Trypanosoma brucei I/6 autoantigen 0.0065 0.0251 0.0765
Schistosoma mansoni hypothetical protein 0.0337 0.1616 0.1616
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0065 0.0251 0.1793
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0126 0.0558 0.1702
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.042 0.2029 0.2029
Loa Loa (eye worm) hypothetical protein 0.0072 0.0285 0.0285
Echinococcus granulosus tissue type plasminogen activator 0.0017 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.2029
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0108 0.0465 0.3325
Echinococcus granulosus EF hand domain containing family member A2 0.0065 0.0251 0.0251
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0122 0.036
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Brugia malayi cathepsin L-like precursor 0.0092 0.0387 0.0387
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0069 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0092 0.0387 0.0387
Plasmodium falciparum serine repeat antigen 5 0.0069 0.0271 0.4853
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Trichomonas vaginalis calpain, putative 0.0126 0.0558 0.1702
Brugia malayi Cathepsin L-like precursor 0.0108 0.0466 0.0466
Trypanosoma brucei centrin-3 0.0121 0.053 0.1615
Echinococcus multilocularis snurportin 1 0.0299 0.1423 0.1423
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Brugia malayi hypothetical protein 0.0043 0.0143 0.0143
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Plasmodium falciparum serine repeat antigen 3 0.0069 0.0271 0.4853
Brugia malayi calpain family protein 1 0.1113 0.5503 0.5503
Brugia malayi calpain family protein 1 0.1113 0.5503 0.5503
Brugia malayi Kringle domain containing protein 0.0017 0.0011 0.0011
Onchocerca volvulus 0.0092 0.0387 0.1139
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0378 0.0378
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0065 0.0251 0.1793
Trypanosoma brucei calmodulin, putative 0.0065 0.0251 0.0765
Leishmania major importin beta-1 subunit, putative 0.0023 0.0039 0.012
Echinococcus multilocularis centrin 2 0.0065 0.0251 0.0251
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0027 0.0122
Brugia malayi Papain family cysteine protease containing protein 0.0085 0.035 0.035
Trichomonas vaginalis calmodulin, putative 0.0121 0.053 0.1615
Onchocerca volvulus 0.0072 0.0285 0.084
Echinococcus multilocularis calpain 5 0.042 0.2029 0.2029
Plasmodium falciparum serine repeat antigen 7 0.0069 0.0271 0.4853
Giardia lamblia Cathepsin B precursor 0.0069 0.0271 0.0826
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Trichomonas vaginalis kakapo, putative 0.0056 0.0205 0.0624
Brugia malayi calpain 5 0.0126 0.0558 0.0558
Trypanosoma cruzi centrin-3 0.0121 0.053 0.053
Toxoplasma gondii calmodulin, putative 0.0056 0.0205 0.0624
Loa Loa (eye worm) hypothetical protein 0.0025 0.0053 0.0053
Echinococcus multilocularis geminin 0.0337 0.1616 0.1616
Toxoplasma gondii EFHC1, putative 0.0065 0.0251 0.0765
Echinococcus multilocularis chromobox protein 1 0.007 0.0276 0.0276
Brugia malayi cathepsin L precursor 0.0069 0.0271 0.0271
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.1702
Onchocerca volvulus 0.0065 0.0251 0.0738
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0069 0.0271 0.0826
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Echinococcus granulosus neuropeptide s receptor 0.0467 0.2264 0.2264
Echinococcus granulosus calpain A 0.1178 0.5828 0.5828
Brugia malayi cathepsin Z-like cysteine proteinase 0.0069 0.0271 0.0271
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0126 0.0558 0.0558
Echinococcus multilocularis calcyphosin protein 0.0056 0.0205 0.0205
Entamoeba histolytica grainin 2 0.0056 0.0205 0.1462
Brugia malayi Cathepsin L-like precursor 0.0108 0.0466 0.0466
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0065 0.0251 0.0251
Loa Loa (eye worm) programmed cell death protein 6 0.0065 0.0251 0.0251
Echinococcus multilocularis EF hand domain containing family member A2 0.0065 0.0251 0.0251
Trichomonas vaginalis centrin, putative 0.0056 0.0205 0.0624
Entamoeba histolytica cysteine protease, putative 0.0069 0.0271 0.1936
Loa Loa (eye worm) hypothetical protein 0.0693 0.3399 0.3399
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0046 0.0046
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0053 0.026
Trichomonas vaginalis calmodulin, putative 0.0065 0.0251 0.0765
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0271 0.0826
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0005 0.0005
Echinococcus multilocularis calmodulin 0.0065 0.0251 0.0251
Schistosoma mansoni chromobox protein 0.007 0.0276 0.0276
Echinococcus granulosus calcyphosin protein 0.0056 0.0205 0.0205
Brugia malayi isocitrate dehydrogenase 0.0019 0.0021 0.0021
Toxoplasma gondii calmodulin CAM2 0.0056 0.0205 0.0624
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.067 0.328 0.328
Trypanosoma brucei Calpain-like protein 2 0.0126 0.0558 0.1702
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.042 0.2029 0.6187
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0108 0.0466 0.1422
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0126 0.0558 0.0558
Onchocerca volvulus 0.0108 0.0466 0.1372
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0011
Plasmodium vivax serine-repeat antigen (SERA) 0.0069 0.0271 0.1335
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0182 0.0182
Entamoeba histolytica cysteine protease, putative 0.0085 0.035 0.2502
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0088

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) < 0.104 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJ-TERT-LT-ST Fibroblast. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1554, AID1674] ChEMBL. No reference
EC50 (functional) = 0.553 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT RAS-Independent Fibroblast. (Class of assay: confirmatory) [Related pubchem assays: 1674 (Project Summary), 1554 (Primary HTS)] ChEMBL. No reference
EC50 (functional) = 1.885 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to BJeLR RAS-Dependent Fibroblast. (Class of assay: confirmatory) [Related pubchem assays: 1674 (Project Summary), 1554 (Primary HTS)] ChEMBL. No reference
EC50 (functional) = 15.057 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT-LT-ST RAS-Independent Fibroblast. (Class of assay: confirmatory) [Related pubchem assays: 1674 (Project Summary), 1554 (Primary HTS)] ChEMBL. No reference
Inhibition (binding) < 1 % Inhibition of chick optic lobe choline acetyltransferase (ChAT) at 10e-4 M ChEMBL. No reference
Inhibition (binding) < 1 % Inhibition of chick optic lobe choline acetyltransferase (ChAT) at 10e-4 M ChEMBL. No reference
Potency (functional) 0.3294 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.5012 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.5174 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.7375 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.8199 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.31 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 2.3934 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 2.5119 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 2.5918 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 3.2643 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.0795 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (binding) 10 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (binding) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) = 79.4328 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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