Detailed information for compound 51374

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 413.444 | Formula: C25H20FN3O2
  • H donors: 1 H acceptors: 1 LogP: 4.52 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)n1c(CCc2c[nH]c3c2cc(F)cc3)nc2c(c1=O)cccc2
  • InChi: 1S/C25H20FN3O2/c1-31-19-6-4-5-18(14-19)29-24(28-23-8-3-2-7-20(23)25(29)30)12-9-16-15-27-22-11-10-17(26)13-21(16)22/h2-8,10-11,13-15,27H,9,12H2,1H3
  • InChiKey: QTASYIGMDJHPPK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus cholecystokinin B receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0061 0.0213 0.0617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0058 0.0193 0.0193
Brugia malayi calpain 7 0.0364 0.1975 0.1975
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0116 0.0095
Loa Loa (eye worm) hypothetical protein 0.1746 1 1
Trichomonas vaginalis centrin, putative 0.0052 0.0157 0.0443
Giardia lamblia Cathepsin L precursor 0.0061 0.0213 0.0217
Giardia lamblia Calmodulin 0.0052 0.0157 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Schistosoma mansoni cathepsin F (C01 family) 0.0085 0.0352 0.0331
Echinococcus granulosus EF hand domain containing family member A2 0.0058 0.0193 0.0172
Loa Loa (eye worm) hypothetical protein 0.0061 0.0213 0.0213
Brugia malayi Myosin regulatory light chain 1 0.0052 0.0157 0.0157
Echinococcus granulosus calcium uptake protein 1 0.0058 0.0193 0.0172
Entamoeba histolytica calmodulin, putative 0.0058 0.0193 0.1033
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0058 0.0196 0.0605
Echinococcus multilocularis programmed cell death protein 0.0109 0.0493 0.0472
Echinococcus multilocularis programmed cell death protein 6 0.0052 0.0157 0.0136
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0494 0.0494
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trypanosoma cruzi cruzipain precursor, putative 0.0101 0.0446 0.0446
Schistosoma mansoni centrin 0.0058 0.0193 0.0172
Echinococcus granulosus chromobox protein 1 0.0068 0.0252 0.0231
Echinococcus multilocularis cysteine protease 0.0101 0.0446 0.0425
Echinococcus multilocularis fk506 binding protein 0.0107 0.0477 0.0456
Loa Loa (eye worm) hypothetical protein 0.0038 0.0079 0.0079
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0145 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Echinococcus multilocularis neurocalcin 0.0058 0.0193 0.0172
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0061
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0107 0.0477 0.1068
Plasmodium falciparum serine repeat antigen 2 0.0061 0.0213 0.4312
Brugia malayi beta-lactamase 0.0035 0.0061 0.0061
Trypanosoma cruzi cysteine proteinase, putative 0.0077 0.0308 0.0308
Plasmodium falciparum cysteine proteinase falcipain 1 0.0077 0.0308 0.6226
Leishmania major hypothetical protein, conserved 0.0058 0.0193 0.0597
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0077 0.0308 0.0286
Trichomonas vaginalis centrin, putative 0.0058 0.0193 0.0556
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0107 0.0477 0.0477
Plasmodium falciparum centrin-1 0.0058 0.0193 0.3915
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0107 0.0477 0.0477
Loa Loa (eye worm) FKBP5 protein 0.0107 0.0477 0.0477
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0101 0.0446 0.0425
Toxoplasma gondii troponin c, isotype gamma, putative 0.0058 0.0193 0.0597
Schistosoma mansoni calpain C (C02 family) 0.0364 0.1975 0.1957
Giardia lamblia Programmed cell death protein-like protein 0.0052 0.0157 0.0036
Leishmania major cysteine peptidase A (CPA) 0.0101 0.0446 0.1377
Entamoeba histolytica grainin 2 0.0109 0.0493 0.3374
Leishmania major hypothetical protein, unknown function 0.011 0.0494 0.1525
Brugia malayi cathepsin F-like cysteine proteinase 0.0061 0.0213 0.0213
Brugia malayi Papain family cysteine protease containing protein 0.0077 0.0308 0.0308
Loa Loa (eye worm) calpain family protein 1 0.0966 0.547 0.547
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0061 0.0147
Schistosoma mansoni rab 0.0058 0.0193 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0061 0.0213 0.1079
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0058 0.0196 0.0196
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0052 0.0159 0.0806
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0061 0.0213 0.0192
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Brugia malayi hypothetical protein 0.0035 0.0061 0.0061
Brugia malayi Kringle domain containing protein 0.0052 0.0159 0.0159
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Onchocerca volvulus Cathepsin F homolog 0.0101 0.0446 0.1251
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0582 0.324 0.3225
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Leishmania major fk506-binding protein 1-like protein 0.0107 0.0477 0.1471
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0061 0.0213 0.0217
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0061 0.0213 0.0617
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1746 1 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0193 0.0193
Echinococcus granulosus cathepsin b 0.1746 1 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0107 0.0477 0.3246
Entamoeba histolytica cysteine proteinase 1, putative 0.0077 0.0308 0.1926
Schistosoma mansoni cathepsin C 0.0061 0.0213 0.0192
Brugia malayi Cathepsin L-like precursor 0.0101 0.0446 0.0446
Schistosoma mansoni calmodulin 0.0058 0.0193 0.0172
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.1975
Toxoplasma gondii cathepsin B 0.0582 0.324 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0308 0.0949
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0193 0.0556
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1024 0.5806 0.5797
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0061 0.0213 0.0617
Trypanosoma cruzi cysteine peptidase, putative 0.0101 0.0446 0.0446
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0203 0.0182
Trypanosoma brucei calpain, putative 0.011 0.0494 0.1525
Giardia lamblia Cathepsin B precursor 0.0061 0.0213 0.0217
Giardia lamblia Cysteine protease 0.0061 0.0213 0.0217
Toxoplasma gondii EF hand domain-containing protein 0.0052 0.0157 0.0485
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0058 0.0193 0.0172
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0203 0.0182
Onchocerca volvulus 0.0052 0.0157 0.038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0116 0.0095
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0061 0.0213 0.0217
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0101 0.0446 0.9034
Trichomonas vaginalis caltractin, putative 0.0052 0.0157 0.0443
Echinococcus multilocularis cathepsin L cysteine protease 0.0101 0.0446 0.0425
Giardia lamblia Cathepsin B precursor 0.0582 0.324 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Schistosoma mansoni hypothetical protein 0.0058 0.0193 0.0172
Trichomonas vaginalis centrin, putative 0.0052 0.0157 0.0443
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0058 0.0193 0.0556
Echinococcus multilocularis cathepsin b 0.1746 1 1
Trypanosoma brucei Calpain-like protein 1.2 0.011 0.0494 0.1525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Schistosoma mansoni calpain (C02 family) 0.0364 0.1975 0.1957
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0107 0.0477 0.0456
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0058 0.0193 0.1033
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0157 0.0443
Schistosoma mansoni hypothetical protein 0.011 0.0494 0.0473
Toxoplasma gondii preprocathepsin c precursor, putative 0.0061 0.0213 0.0657
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1024 0.5806 0.5797
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0107 0.0477 1
Entamoeba histolytica calcium binding family protein 0.0058 0.0193 0.1033
Plasmodium falciparum centrin-4 0.0052 0.0157 0.318
Brugia malayi MAP kinase sur-1 0.005 0.0146 0.0146
Giardia lamblia Cysteine protease 0.0061 0.0213 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0061 0.0213 0.0617
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0058 0.0193 0.0193
Trypanosoma brucei Calpain-like protein 1.1 0.011 0.0494 0.1525
Trypanosoma brucei calmodulin, putative 0.0058 0.0193 0.0597
Trichomonas vaginalis calcium binding proteins, putative 0.0058 0.0193 0.0556
Echinococcus granulosus EF HAND 1 calcium binding site 0.0058 0.0193 0.0172
Giardia lamblia Cathepsin B precursor 0.0061 0.0213 0.0217
Echinococcus granulosus calpain A 0.0364 0.1975 0.1957
Plasmodium falciparum serine repeat antigen 7 0.0061 0.0213 0.4312
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0582 0.324 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Echinococcus multilocularis calpain 0.0364 0.1975 0.1957
Echinococcus multilocularis neuronal calcium sensor 0.0058 0.0193 0.0172
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0494 0.0494
Echinococcus granulosus calcyphosin protein 0.0052 0.0157 0.0136
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0052 0.0157 0.0443
Schistosoma mansoni hypothetical protein 0.0052 0.0159 0.0138
Loa Loa (eye worm) hypothetical protein 0.0101 0.0446 0.0446
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0061 0.0213 0.4312
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0061 0.0213 0.0617
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.116 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.011 0.0494 0.1488
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0095 0.0194
Plasmodium falciparum serine repeat antigen 8 0.0061 0.0213 0.4312
Trypanosoma cruzi cysteine peptidase, putative 0.0101 0.0446 0.0446
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0145 0.0145
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Onchocerca volvulus 0.0101 0.0446 0.1251
Loa Loa (eye worm) myosin Light Chain family member 0.0052 0.0157 0.0157
Schistosoma mansoni calmodulin related calcium binding protein 0.0058 0.0193 0.0172
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0146 0.0451
Schistosoma mansoni calmodulin 0.0058 0.0193 0.0172
Entamoeba histolytica cysteine protease, putative 0.0061 0.0213 0.1186
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0061
Echinococcus multilocularis chromobox protein 1 0.0068 0.0252 0.0231
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0061 0.0213 0.1079
Schistosoma mansoni myosin light chain 0.0052 0.0157 0.0136
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0546 0.0546
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.011 0.0494 0.1525
Trypanosoma cruzi centrin-3 0.0109 0.0493 0.0493
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1746 1 1
Echinococcus granulosus cathepsin L 0.0077 0.0308 0.0286
Onchocerca volvulus 0.0058 0.0193 0.0489
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0061 0.0213 0.0617
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0107 0.0477 0.0477
Toxoplasma gondii calmodulin CAM2 0.0052 0.0157 0.0485
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0203 0.0182
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.011 0.0494 0.1525
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0061 0.0213 0.1079
Brugia malayi Papain family cysteine protease containing protein 0.0061 0.0213 0.0213
Echinococcus granulosus calpain 5 0.0364 0.1975 0.1957
Onchocerca volvulus 0.0602 0.3353 1
Trypanosoma brucei Component of motile flagella 41 0.0058 0.0193 0.0597
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0107 0.0477 0.5
Giardia lamblia Cathepsin B precursor 0.0061 0.0213 0.0217
Entamoeba histolytica cysteine protease, putative 0.0061 0.0213 0.1186
Leishmania major programmed cell death 6 protein-like protein 0.0058 0.0193 0.0597
Leishmania major kinesin, putative 0.0255 0.1338 0.413
Brugia malayi Papain family cysteine protease containing protein 0.0077 0.0308 0.0308
Trypanosoma brucei cysteine peptidase C (CPC) 0.0582 0.324 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0061 0.0213 0.0617
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0116 0.0095
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0061 0.0213 0.0213
Loa Loa (eye worm) beta-lactamase 0.0035 0.0061 0.0061
Trichomonas vaginalis calcium binding protein, putative 0.0058 0.0193 0.0556
Loa Loa (eye worm) hypothetical protein 0.0602 0.3353 0.3353
Leishmania major hypothetical protein, conserved 0.0035 0.0061 0.0189
Loa Loa (eye worm) TK/ROR protein kinase 0.0052 0.0159 0.0159
Echinococcus granulosus cathepsin l cysteine peptidase 0.0101 0.0446 0.0425
Echinococcus granulosus tissue type plasminogen activator 0.0052 0.0159 0.0138
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0146 0.0125
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0061 0.004
Leishmania major calmodulin, putative 0.0058 0.0193 0.0597
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0146 0.0146
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0061 0.0213 0.0192
Schistosoma mansoni hypothetical protein 0.0035 0.0061 0.004
Brugia malayi RasGEF domain containing protein 0.0052 0.0157 0.0157
Trichomonas vaginalis calpain, putative 0.011 0.0494 0.1488
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.1975 0.1975
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0079 0.02
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0582 0.324 0.324
Loa Loa (eye worm) hypothetical protein 0.0061 0.0213 0.0213
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0061 0.0213 0.0217
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Brugia malayi cathepsin L-like precursor 0.0085 0.0352 0.0352
Schistosoma mansoni Mername-AA248 (C02 family) 0.0364 0.1975 0.1957
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0061 0.0213 0.0192
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0061 0.0213 0.0617
Schistosoma mansoni immunophilin 0.0107 0.0477 0.0456
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0107 0.0477 0.1434
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0079 0.02
Entamoeba histolytica cysteine protease, putative 0.0061 0.0213 0.1186
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0061 0.0147
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0058 0.0196 0.0993
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0061 0.0213 0.1079
Plasmodium vivax unspecified product 0.0061 0.0213 0.1079
Trypanosoma cruzi kinesin, putative 0.0255 0.1338 0.1338
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0193 0.0556
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.011 0.0494 0.1488
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0146 0.0146
Echinococcus granulosus neuropeptide s receptor 0.0456 0.2505 0.2489
Giardia lamblia Cathepsin B precursor 0.0061 0.0213 0.0217
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0058 0.0193 0.0597
Echinococcus multilocularis calpain A 0.1024 0.5806 0.5797
Entamoeba histolytica calpain family cysteine protease, putative 0.011 0.0494 0.3382
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0213 0.0617
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0061 0.0147
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0203 0.0628
Trypanosoma cruzi cysteine peptidase, putative 0.0101 0.0446 0.0446
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.1975 0.1975
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0052 0.0157 0.038
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0107 0.0477 0.1068
Echinococcus multilocularis cysteine protease 0.0101 0.0446 0.0425
Entamoeba histolytica cysteine proteinase, putative 0.0077 0.0308 0.1926
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0061 0.0213 0.0617
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Leishmania major calpain protease-like protein 0.011 0.0494 0.1525
Brugia malayi fibroinase precursor 0.0061 0.0213 0.0213
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0966 0.547 0.546
Loa Loa (eye worm) hypothetical protein 0.0966 0.547 0.547
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0107 0.0477 0.0456
Echinococcus multilocularis geminin 0.0171 0.0852 0.0832
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0052 0.0157 0.0795
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0146 0.0146
Trypanosoma cruzi cysteine proteinase, putative 0.0077 0.0308 0.0308
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0308 0.0308
Echinococcus granulosus programmed cell death protein 6 0.0052 0.0157 0.0136
Trypanosoma cruzi I/6 autoantigen, putative 0.0058 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Entamoeba histolytica cysteine proteinase, putative 0.0085 0.0352 0.227
Leishmania major calcineurin B subunit, putative 0.0058 0.0193 0.0597
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0061 0.0213 0.1186
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Echinococcus multilocularis calpain 5 0.0364 0.1975 0.1957
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.011 0.0494 0.1488
Brugia malayi Cathepsin L-like precursor 0.0101 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0085 0.0352 0.0352
Brugia malayi Probable myosin regulatory light chain 0.0052 0.0157 0.0157
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0061 0.0213 0.1079
Leishmania major hypothetical protein, conserved 0.0058 0.0193 0.0597
Brugia malayi calpain 5 0.0255 0.1338 0.1338
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0107 0.0477 0.0456
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0364 0.1975 0.1975
Plasmodium vivax serine-repeat antigen (SERA) 0.0061 0.0213 0.1079
Loa Loa (eye worm) hypothetical protein 0.0061 0.0213 0.0213
Plasmodium falciparum serine repeat antigen 9 0.0061 0.0213 0.4312
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0193 0.0172
Trypanosoma brucei I/6 autoantigen 0.0058 0.0193 0.0597
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Schistosoma mansoni hypothetical protein 0.0171 0.0852 0.0832
Onchocerca volvulus 0.0101 0.0446 0.1251
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0203 0.342
Echinococcus multilocularis calpain 7 (C02 family) 0.0364 0.1975 0.1957
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0145 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0308 0.091
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0252 0.0737
Schistosoma mansoni reticulocalbin 0.0058 0.0193 0.0172
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.011 0.0494 0.1488
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0077 0.0308 0.091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0061 0.0213 0.0617
Echinococcus granulosus cathepsin L 0.0061 0.0213 0.0192
Trypanosoma cruzi cysteine protease, putative 0.0077 0.0308 0.0308
Toxoplasma gondii hypothetical protein 0.011 0.0494 0.1525
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0061 0.0061
Plasmodium falciparum cysteine repeat modular protein 1 0.0052 0.0159 0.322
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0101 0.0446 0.9034
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0101 0.0446 0.134
Plasmodium falciparum calpain 0.011 0.0494 1
Brugia malayi Heterochromatin protein 1 0.0068 0.0252 0.0252
Plasmodium vivax serine-repeat antigen (SERA) 0.0061 0.0213 0.1079
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0061 0.0213 0.0192
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1746 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0101 0.0446 0.0446
Trichomonas vaginalis immunophilin, putative 0.0107 0.0477 0.1434
Echinococcus granulosus Myosin regulatory light chain 0.0052 0.0157 0.0136
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trichomonas vaginalis calcium binding protein, putative 0.0058 0.0193 0.0556
Schistosoma mansoni calmodulin-related 0.0052 0.0157 0.0136
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0061 0.0213 0.0192
Plasmodium falciparum serine repeat antigen 6 0.0061 0.0213 0.4312
Trichomonas vaginalis calcium binding protein, putative 0.0109 0.0493 0.1485
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0058 0.0193 0.0556
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0061
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0061 0.0213 0.0217
Onchocerca volvulus Cathepsin L homolog 0.0061 0.0213 0.0548
Trichomonas vaginalis myosin light chain 1, putative 0.0058 0.0193 0.0556
Giardia lamblia Hypothetical protein 0.0061 0.0213 0.0217
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0494 0.0494
Brugia malayi Importin beta-1 subunit 0.0028 0.0022 0.0022
Trypanosoma cruzi conserved protein 0.011 0.0494 0.0494
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Loa Loa (eye worm) hypothetical protein 0.0102 0.0448 0.0448
Echinococcus multilocularis chromobox protein 1 0.0068 0.0252 0.0231
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.011 0.0494 0.1488
Leishmania major calmodulin-like protein 0.0058 0.0193 0.0597
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Trypanosoma brucei calpain-like protein, putative 0.0364 0.1975 0.6095
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0146 0.0125
Brugia malayi EF hand family protein 0.0058 0.0193 0.0193
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0364 0.1975 0.6095
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0352 0.1047
Leishmania major i/6 autoantigen-like protein 0.0058 0.0193 0.0597
Loa Loa (eye worm) programmed cell death protein 6 0.0058 0.0193 0.0193
Plasmodium falciparum serine repeat antigen 1 0.0061 0.0213 0.4312
Entamoeba histolytica cysteine protease, putative 0.0101 0.0446 0.301
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0061 0.0213 0.0617
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.011 0.0494 0.0494
Entamoeba histolytica cysteine proteinase, putative 0.0077 0.0308 0.1926
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.1975
Schistosoma mansoni myosin regulatory light chain 0.0052 0.0157 0.0136
Echinococcus multilocularis centrin 2 0.0058 0.0193 0.0172
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0058 0.0193 0.0193
Entamoeba histolytica calpain large subunit domain III containing protein 0.0255 0.1338 0.998
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0107 0.0477 0.2413
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Echinococcus granulosus neurocalcin 0.0058 0.0193 0.0172
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Onchocerca volvulus 0.0061 0.0213 0.0548
Echinococcus granulosus geminin 0.0171 0.0852 0.0832
Giardia lamblia Cathepsin B precursor 0.0582 0.324 1
Schistosoma mansoni myosin regulatory light chain 0.0052 0.0157 0.0136
Toxoplasma gondii cathepsin CPC2 0.0061 0.0213 0.0657
Trypanosoma brucei calpain-like protein, putative 0.0364 0.1975 0.6095
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0494 0.0494
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0061 0.004
Brugia malayi chromobox protein homolog 3 0.0038 0.0079 0.0079
Plasmodium vivax vivapain-3 0.0077 0.0308 0.1558
Leishmania major centrin, putative 0.0058 0.0193 0.0597
Trichomonas vaginalis kakapo, putative 0.0052 0.0157 0.0443
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0146 0.0146
Echinococcus granulosus snurportin 1 0.0302 0.1611 0.1592
Entamoeba histolytica calcium-binding protein, putative 0.0058 0.0193 0.1033
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0146 0.0125
Onchocerca volvulus 0.0101 0.0446 0.1251
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.011 0.0494 0.0494
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0061 0.0061
Trichomonas vaginalis esterase, putative 0.0035 0.0061 0.0147
Brugia malayi cathepsin L-like cysteine proteinase 0.0061 0.0213 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Echinococcus multilocularis calmodulin 0.0058 0.0193 0.0172
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0494 0.0494
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.6095
Trypanosoma brucei caltractin, putative 0.0109 0.0493 0.1522
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trypanosoma brucei kinesin, putative 0.0255 0.1338 0.413
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0052 0.0157 0.038
Plasmodium vivax vivapain-2 0.0101 0.0446 0.226
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0058 0.0193 0.0193
Echinococcus multilocularis EF hand domain containing family member A2 0.0058 0.0193 0.0172
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0107 0.0477 0.0477
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0058 0.0193 0.0172
Trichomonas vaginalis hypothetical protein 0.011 0.0494 0.1488
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0061 0.0061
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0146 0.0409
Brugia malayi calcium-binding protein 0.0058 0.0193 0.0193
Trypanosoma cruzi calmodulin, putative 0.0058 0.0193 0.0193
Entamoeba histolytica cysteine proteinase, putative 0.0077 0.0308 0.1926
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0061 0.0147
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0061 0.0213 0.4312
Mycobacterium leprae Probable lipase LipE 0.0035 0.0061 0.5
Entamoeba histolytica cysteine proteinase 2 0.0077 0.0308 0.1926
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Brugia malayi Neuronal calcium sensor family protein 1 0.0052 0.0157 0.0157
Trichomonas vaginalis calcium binding protein, putative 0.0058 0.0193 0.0556
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0116 0.0095
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0061 0.0213 0.0192
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0203 0.0182
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0054
Giardia lamblia Cathepsin B precursor 0.0061 0.0213 0.0217
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0058 0.0193 0.0172
Onchocerca volvulus 0.0035 0.0061 0.0092
Trichomonas vaginalis calmodulin, putative 0.0109 0.0493 0.1485
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0061 0.0213 0.1079
Schistosoma mansoni centrin-related 0.0058 0.0193 0.0172
Entamoeba histolytica calmodulin, putative 0.0058 0.0193 0.1033
Loa Loa (eye worm) cathepsin B 0.0582 0.324 0.324
Echinococcus granulosus cathepsin l1 0.0085 0.0352 0.0331
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0193 0.0172
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0102 0.0448 0.0427
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0061 0.0213 0.0192
Onchocerca volvulus 0.0102 0.0448 0.1255
Trichomonas vaginalis centrin, putative 0.0052 0.0157 0.0443
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0193 0.0597
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Loa Loa (eye worm) calmodulin-like protein 0.0058 0.0193 0.0193
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0022 0.0067
Leishmania major centrin, putative 0.0058 0.0193 0.0597
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0116 0.0095
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0079 0.0144
Leishmania major hypothetical protein, conserved 0.0052 0.0159 0.0491
Echinococcus granulosus centrin 2 0.0058 0.0193 0.0172
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0085 0.0352 0.0352
Trichomonas vaginalis caltractin, putative 0.0052 0.0157 0.0443
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.1611 0.1611
Trichomonas vaginalis calpain, putative 0.011 0.0494 0.1488
Plasmodium vivax unspecified product 0.0077 0.0308 0.1558
Trypanosoma cruzi caltractin, putative 0.0058 0.0193 0.0193
Echinococcus multilocularis EF hand domain containing family member A2 0.0058 0.0193 0.0172
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.011 0.0494 0.1525
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0092 0.0391 0.037
Echinococcus granulosus calpain A 0.1024 0.5806 0.5797
Giardia lamblia Hypothetical protein 0.0061 0.0213 0.0217
Leishmania major phospholipase c-like protein 0.0058 0.0193 0.0597
Giardia lamblia Cathepsin B precursor 0.0582 0.324 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0061 0.0213 0.0213
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0077 0.0308 0.0286
Brugia malayi MH2 domain containing protein 0.0118 0.0546 0.0546
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0022 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Giardia lamblia Encystation-specific protease 0.0061 0.0213 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trypanosoma brucei protein I/6 0.0058 0.0193 0.0597
Entamoeba histolytica cysteine proteinase, putative 0.0077 0.0308 0.1926
Trypanosoma brucei calpain-like protein, putative 0.0364 0.1975 0.6095
Brugia malayi cathepsin Z-like cysteine proteinase 0.0061 0.0213 0.0213
Brugia malayi Cathepsin L-like precursor 0.0101 0.0446 0.0446
Leishmania major calmodulin-like protein 0.0058 0.0193 0.0597
Echinococcus multilocularis cathepsin b 0.1746 1 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.011 0.0494 0.1488
Toxoplasma gondii centrin family protein 0.0052 0.0157 0.0485
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0061 0.0213 0.1079
Loa Loa (eye worm) hypothetical protein 0.0092 0.0391 0.0391
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0061 0.004
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.6095
Loa Loa (eye worm) hypothetical protein 0.0711 0.3989 0.3989
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0101 0.0446 0.0446
Toxoplasma gondii EFHC1, putative 0.0058 0.0193 0.0597
Trichomonas vaginalis calcineurin B subunit, putative 0.0058 0.0193 0.0556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Loa Loa (eye worm) hypothetical protein 0.0857 0.4834 0.4834
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0203 0.342
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0101 0.0446 0.134
Toxoplasma gondii calmodulin, putative 0.0052 0.0157 0.0485
Onchocerca volvulus 0.0101 0.0446 0.1251
Echinococcus multilocularis calumenin 0.0058 0.0193 0.0172
Plasmodium vivax centrin-1, putative 0.0058 0.0193 0.0979
Trypanosoma brucei centrin, putative 0.0058 0.0193 0.0597
Entamoeba histolytica calmodulin, putative 0.0052 0.0157 0.0749
Leishmania major centrin, putative,caltractin, putative 0.0058 0.0193 0.0597
Echinococcus granulosus calmodulin 0.0058 0.0193 0.0172
Loa Loa (eye worm) hypothetical protein 0.0102 0.0448 0.0448
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0146 0.0409
Loa Loa (eye worm) hypothetical protein 0.0052 0.0157 0.0157
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Echinococcus multilocularis Calcium binding protein 0.0052 0.0157 0.0136
Toxoplasma gondii cathepsin CPL 0.0101 0.0446 0.1377
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.1975
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0061
Echinococcus granulosus cathepsin l1 0.0101 0.0446 0.0425
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.1975 0.1975
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.0446 0.301
Loa Loa (eye worm) ctsf protein 0.0101 0.0446 0.0446
Entamoeba histolytica grainin, putative 0.0058 0.0193 0.1033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Loa Loa (eye worm) hypothetical protein 0.003 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0302 0.1611 0.1592
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0546 0.0546
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0061 0.0189
Brugia malayi calpain family protein 1 0.0966 0.547 0.547
Loa Loa (eye worm) EF hand family protein 0.0058 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0061 0.0213 0.0617
Trichomonas vaginalis calmodulin, putative 0.0052 0.0157 0.0443
Onchocerca volvulus 0.0058 0.0193 0.0489
Loa Loa (eye worm) hypothetical protein 0.0061 0.0213 0.0213
Onchocerca volvulus 0.0035 0.0061 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0061 0.0213 0.0617
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0193 0.0979
Echinococcus granulosus neuronal calcium sensor 0.0058 0.0193 0.0172
Echinococcus granulosus cathepsin L cysteine protease 0.0077 0.0308 0.0286
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0077 0.0308 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0085 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0049 0.0145 0.0145
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0107 0.0477 0.0456
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0193 0.0172
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1024 0.5806 0.5797
Brugia malayi Protein kinase domain containing protein 0.0052 0.0159 0.0159
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0146 0.0125
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trypanosoma brucei cysteine peptidase, putative 0.011 0.0494 0.1525
Trypanosoma cruzi I/6 autoantigen, putative 0.0058 0.0193 0.0193
Loa Loa (eye worm) calpain 0.0364 0.1975 0.1975
Trichomonas vaginalis fk506-binding protein, putative 0.0107 0.0477 0.1434
Brugia malayi cathepsin L precursor 0.0061 0.0213 0.0213
Brugia malayi calpain 5 0.011 0.0494 0.0494
Trichomonas vaginalis calcium binding protein, putative 0.0052 0.0157 0.0443
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0159
Trypanosoma brucei calmodulin, putative 0.0058 0.0193 0.0597
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Trypanosoma brucei mitochondrial calcium uptake 1 0.0058 0.0193 0.0597
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.0494 0.1525
Brugia malayi Calmodulin-like protein 0.0058 0.0193 0.0193
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0061 0.0147
Echinococcus granulosus calpain 7 C02 family 0.0364 0.1975 0.1957
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0203 0.1293
Loa Loa (eye worm) hypothetical protein 0.0052 0.0157 0.0157
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0061 0.0213 0.0213
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0061 0.0213 0.1186
Onchocerca volvulus 0.0035 0.0061 0.0092
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1746 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Echinococcus multilocularis calcyphosin protein 0.0052 0.0157 0.0136
Entamoeba histolytica protein kinase, putative 0.0255 0.1341 1
Brugia malayi Trypsin family protein 0.0102 0.0448 0.0448
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Plasmodium vivax importin-beta 2, putative 0.0028 0.0022 0.011
Plasmodium falciparum serine repeat antigen 4 0.0061 0.0213 0.4312
Entamoeba histolytica hypothetical protein, conserved 0.0058 0.0193 0.1033
Brugia malayi Cathepsin L-like precursor 0.0101 0.0446 0.0446
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0058 0.0193 0.1033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0061 0.0213 0.0617
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.6095
Loa Loa (eye worm) myosin regulatory light chain 1 0.0052 0.0157 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Loa Loa (eye worm) calpain D 0.011 0.0494 0.0494
Giardia lamblia Cathepsin L precursor 0.0061 0.0213 0.0217
Onchocerca volvulus 0.0058 0.0193 0.0489
Plasmodium falciparum serine repeat antigen 5 0.0061 0.0213 0.4312
Loa Loa (eye worm) hypothetical protein 0.0061 0.0213 0.0213
Entamoeba histolytica cysteine protease, putative 0.0061 0.0213 0.1186
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0092 0.0391 0.037
Trypanosoma cruzi calmodulin, putative 0.0058 0.0193 0.0193
Echinococcus multilocularis calbindin 32 0.0058 0.0193 0.0172
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0061 0.5
Trypanosoma brucei hypothetical protein 0.011 0.0494 0.1525
Brugia malayi programmed cell death protein 6 0.0058 0.0193 0.0193
Leishmania major calpain family cysteine protease-like protein 0.011 0.0494 0.1525
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0203 0.342
Onchocerca volvulus Cathepsin L homolog 0.0101 0.0446 0.1251
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0061 0.0213 0.1079
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.011 0.0494 0.0494
Onchocerca volvulus Cathepsin L homolog 0.0101 0.0446 0.1251
Echinococcus granulosus chromobox protein 1 0.0068 0.0252 0.0231
Toxoplasma gondii ABC1 family protein 0.0035 0.0061 0.0189
Trypanosoma cruzi calmodulin, putative 0.0058 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0061 0.0213 0.0617
Trypanosoma cruzi centrin, putative 0.0109 0.0493 0.0493
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0061 0.0311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Echinococcus granulosus Calcium binding protein 0.0052 0.0157 0.0136
Trichomonas vaginalis calpain, putative 0.011 0.0494 0.1488
Loa Loa (eye worm) cysteine protease 0.0101 0.0446 0.0446
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0146 0.0451
Trypanosoma brucei centrin, putative 0.0058 0.0193 0.0597
Entamoeba histolytica grainin 2 0.0052 0.0157 0.0749
Plasmodium vivax vivapain-1 0.0077 0.0308 0.1558
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0058 0.0193 0.0172
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0107 0.0477 0.1434
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0352 0.1047
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Onchocerca volvulus 0.0101 0.0446 0.1251
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0095 0.0252
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.1975 0.1975
Trypanosoma brucei protein kinase, putative 0.005 0.0146 0.0451
Echinococcus granulosus cathepsin L cysteine proteinase 0.0101 0.0446 0.0425
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0061 0.0213 0.1079
Plasmodium falciparum cysteine proteinase falcipain 3 0.0101 0.0446 0.9034
Schistosoma mansoni calpain-7 (C02 family) 0.0364 0.1975 0.1957
Giardia lamblia Cathepsin L precursor 0.0061 0.0213 0.0217
Trypanosoma brucei centrin-3 0.0109 0.0493 0.1522
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0061 0.0213 0.0192
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0061 0.0061
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0101 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0052 0.0157 0.0157
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0058 0.0196 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0061 0.0213 0.0617
Plasmodium falciparum serine repeat antigen 3 0.0061 0.0213 0.4312
Entamoeba histolytica hypothetical protein 0.0061 0.0213 0.1186
Echinococcus granulosus calbindin 32 0.0058 0.0193 0.0172
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0077 0.0308 0.0308
Echinococcus granulosus cathepsin b 0.1746 1 1
Schistosoma mansoni hypothetical protein 0.0058 0.0193 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0308 0.0949
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0107 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0061 0.0213 0.0213
Brugia malayi cathepsin Z-like cysteine proteinase 0.0061 0.0213 0.0213
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0061 0.0213 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0146 0.0125
Plasmodium vivax vivapain-2 0.0101 0.0446 0.226
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0159 0.0159
Onchocerca volvulus 0.0052 0.0157 0.038
Schistosoma mansoni reticulocalbin 0.0058 0.0193 0.0172
Giardia lamblia Cathepsin L-like protease 0.0061 0.0213 0.0217
Brugia malayi RNA, U transporter 1 0.008 0.0324 0.0324
Trypanosoma cruzi kinesin, putative 0.0255 0.1338 0.1338
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0213 0.0213
Brugia malayi Papain family cysteine protease containing protein 0.0061 0.0213 0.0213
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0582 0.324 1
Trypanosoma brucei antigen, putative 0.0364 0.1975 0.6095
Giardia lamblia Cysteine protease 0.0061 0.0213 0.0217
Brugia malayi Cathepsin L-like precursor 0.0085 0.0352 0.0352
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Schistosoma mansoni immunophilin 0.0092 0.0391 0.037
Echinococcus multilocularis cathepsin L 0.0077 0.0308 0.0286
Toxoplasma gondii centrin, putative 0.0058 0.0193 0.0597
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0107 0.0477 0.0477
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0054 0.0054
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0213 0.0213
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1024 0.5806 0.5797
Brugia malayi calpain D 0.011 0.0494 0.0494
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0107 0.0477 0.0477
Schistosoma mansoni immunophilin 0.0107 0.0477 0.0456
Onchocerca volvulus 0.0085 0.0352 0.0966
Trichomonas vaginalis calcineurin B subunit, putative 0.0058 0.0193 0.0556
Echinococcus multilocularis tissue type plasminogen activator 0.0052 0.0159 0.0138
Schistosoma mansoni hypothetical protein 0.0034 0.0054 0.0032
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.6095
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0116 0.0116
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Echinococcus granulosus EF hand domain containing family member A2 0.0058 0.0193 0.0172
Toxoplasma gondii kringle domain-containing protein 0.0052 0.0159 0.0491
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0107 0.0477 0.1471
Echinococcus multilocularis Myosin regulatory light chain 0.0052 0.0157 0.0136
Schistosoma mansoni chromobox protein 0.0068 0.0252 0.0231
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0107 0.0477 0.1471
Loa Loa (eye worm) calpain family protein 1 0.0711 0.3989 0.3989
Brugia malayi Papain family cysteine protease containing protein 0.0101 0.0446 0.0446
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.0494
Giardia lamblia Cathepsin L precursor 0.0061 0.0213 0.0217
Schistosoma mansoni mitochondrial solute carrier 0.0058 0.0193 0.0172
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.2505 0.2489
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0252 0.0737
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0146 0.0451
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.2505 0.2489
Schistosoma mansoni ef hand domain family member A2 0.0058 0.0193 0.0172
Trypanosoma cruzi centrin, putative 0.0109 0.0493 0.0493
Onchocerca volvulus 0.0101 0.0446 0.1251
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0101 0.0446 0.0425
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0116 0.0095
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0061 0.0213 0.4312
Giardia lamblia Cathepsin L-like protease 0.0061 0.0213 0.0217
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0252 0.0252
Trypanosoma brucei Calpain-like protein CALP1.3 0.011 0.0494 0.1525
Toxoplasma gondii calmodulin CAM1 0.0058 0.0193 0.0597
Brugia malayi Cathepsin L-like precursor 0.0101 0.0446 0.0446
Toxoplasma gondii centrin 0.0058 0.0193 0.0597
Schistosoma mansoni calpain-7 (C02 family) 0.0364 0.1975 0.1957
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0146 0.0146
Onchocerca volvulus 0.0086 0.0357 0.0982
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0146 0.0409
Toxoplasma gondii cathepsin CPC1 0.0061 0.0213 0.0657
Schistosoma mansoni cathepsin B (C01 family) 0.0061 0.0213 0.0192
Echinococcus multilocularis cathepsin L 0.0061 0.0213 0.0192
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0116 0.0095
Brugia malayi Cathepsin L-like cysteine proteinase 0.0085 0.0352 0.0352
Toxoplasma gondii EF hand domain-containing protein 0.0058 0.0193 0.0597
Leishmania major peptidylprolyl isomerase-like protein 0.0107 0.0477 0.1471
Schistosoma mansoni calpain-2 (C02 family) 0.011 0.0494 0.0473
Echinococcus multilocularis hypothetical protein 0.0364 0.1975 0.1957
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0107 0.0477 0.9647
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0061 0.004
Loa Loa (eye worm) hypothetical protein 0.0085 0.0352 0.0352
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trypanosoma brucei Calpain-like protein 2 0.011 0.0494 0.1525
Entamoeba histolytica cysteine protease, putative 0.0061 0.0213 0.1186
Giardia lamblia Cathepsin L precursor 0.0061 0.0213 0.0217
Echinococcus multilocularis calcium uptake protein 1 0.0058 0.0193 0.0172
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0061 0.0213 0.1079
Trypanosoma cruzi calpain cysteine peptidase, putative 0.011 0.0494 0.0494
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0494 0.1488
Leishmania major hypothetical protein, conserved 0.011 0.0494 0.1525
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Giardia lamblia Hypothetical protein 0.0058 0.0193 0.0153
Echinococcus multilocularis snurportin 1 0.0302 0.1611 0.1592
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0203 0.0628
Onchocerca volvulus 0.0052 0.0159 0.0386
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Loa Loa (eye worm) fibroinase 0.0101 0.0446 0.0446
Onchocerca volvulus 0.0101 0.0446 0.1251
Toxoplasma gondii calcium-dependent protein kinase 0.0058 0.0196 0.0605
Giardia lamblia Cysteine protease 0.0061 0.0213 0.0217
Loa Loa (eye worm) calpain 5 0.0255 0.1338 0.1338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Schistosoma mansoni cathepsin F (C01 family) 0.0101 0.0446 0.0425
Brugia malayi Cathepsin L-like precursor 0.0085 0.0352 0.0352
Toxoplasma gondii calcium binding protein precursor, putative 0.0052 0.0157 0.0485
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0061
Entamoeba histolytica cysteine protease, putative 0.0077 0.0308 0.1926
Brugia malayi Papain family cysteine protease containing protein 0.0061 0.0213 0.0213
Schistosoma mansoni cathepsin F (C01 family) 0.0101 0.0446 0.0425
Brugia malayi Cathepsin L-like precursor 0.0101 0.0446 0.0446
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0061 0.004
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.1975 0.1975
Brugia malayi beta-lactamase family protein 0.0035 0.0061 0.0061
Echinococcus multilocularis cathepsin L cysteine protease 0.0101 0.0446 0.0425
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.0446 0.301
Plasmodium falciparum importin beta, putative 0.0028 0.0022 0.044
Leishmania major cathepsin L-like protease 0.0101 0.0446 0.1377
Giardia lamblia Cathepsin L precursor 0.0061 0.0213 0.0217
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1746 1 1
Trypanosoma brucei calpain-like protein, putative 0.0364 0.1975 0.6095
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0102 0.0448 0.0427
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0157 0.0157
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0058 0.0193 0.0172
Echinococcus multilocularis calpain family protein 1, d 0.0711 0.3989 0.3976
Entamoeba histolytica cysteine protease, putative 0.0061 0.0213 0.1186
Echinococcus multilocularis programmed cell death protein 0.0109 0.0493 0.0472
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0022 0.0067
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0193 0.0172
Brugia malayi beta-lactamase family protein 0.0035 0.0061 0.0061
Trichomonas vaginalis calmodulin-2, putative 0.0058 0.0193 0.0556
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.4408 0.4396
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.2505 0.2489
Echinococcus granulosus cysteine protease 0.0077 0.0308 0.0286
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0061 0.004
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0095 0.0252
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0107 0.0477 0.3246
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0061
Brugia malayi calpain family protein 1 0.0966 0.547 0.547
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0213 0.0617
Trypanosoma brucei calpain, putative 0.011 0.0494 0.1525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Schistosoma mansoni cathepsin S (C01 family) 0.0061 0.0213 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0446 0.134
Echinococcus granulosus calpain 0.0364 0.1975 0.1957
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Brugia malayi EF hand family protein 0.0058 0.0193 0.0193
Echinococcus multilocularis calmodulin 0.0058 0.0193 0.0172
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0146 0.0451
Trichomonas vaginalis centrin, putative 0.0058 0.0193 0.0556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0446 0.134
Trichomonas vaginalis calmodulin, putative 0.0058 0.0193 0.0556
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.1975 0.1975
Loa Loa (eye worm) hypothetical protein 0.0058 0.0193 0.0193
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0061 0.004
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0146 0.0409
Leishmania major calmodulin, putative 0.0058 0.0193 0.0597
Schistosoma mansoni chromobox protein 0.0068 0.0252 0.0231
Leishmania major protein kinase, putative 0.0058 0.0196 0.0605
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.0494 0.0494
Echinococcus granulosus programmed cell death protein 0.0109 0.0493 0.0472
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0061 0.0213 0.0192
Schistosoma mansoni hypothetical protein 0.0171 0.0852 0.0832
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0061 0.0213 0.0617
Plasmodium vivax calpain, putative 0.0364 0.1975 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.0494 0.1525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.0446 0.1377
Echinococcus granulosus calumenin 0.0058 0.0193 0.0172

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.11 uM Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes. ChEMBL. 2016728
IC50 (binding) = 0.11 uM Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes. ChEMBL. 2016728

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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