Detailed information for compound 1032254

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 287.185 | Formula: C13H16Cl2N2O
  • H donors: 1 H acceptors: 2 LogP: 3.07 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(Cn1cncc1)CCc1ccc(cc1)Cl.Cl
  • InChi: 1S/C13H15ClN2O.ClH/c14-12-4-1-11(2-5-12)3-6-13(17)9-16-8-7-15-10-16;/h1-2,4-5,7-8,10,13,17H,3,6,9H2;1H
  • InChiKey: FOWKIYODNNRJDZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Heme oxygenase 2 Starlite/ChEMBL References
Rattus norvegicus Heme oxygenase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans heme oxygenase induced when hemin is sole source of iron Get druggable targets OG5_130942 All targets in OG5_130942
Candida albicans heme oxygenase induced when hemin is sole source of iron Get druggable targets OG5_130942 All targets in OG5_130942
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans heme oxygenase induced when hemin is sole source of iron Heme oxygenase 1   289 aa 232 aa 24.6 %
Candida albicans heme oxygenase induced when hemin is sole source of iron Heme oxygenase 1   289 aa 232 aa 24.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni notch 0.0064 0.0117 0.013
Trypanosoma brucei metacaspase 5, putative 0.0172 0.0456 0.0768
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0072 0.0211
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0096 0.0106
Trichomonas vaginalis calcium binding protein, putative 0.0106 0.0247 0.0745
Brugia malayi hypothetical protein 0.004 0.004 0.004
Echinococcus multilocularis protein jagged 2 0.0064 0.0117 0.013
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0072 0.0142 0.0235
Echinococcus granulosus neurocalcin 0.0106 0.0247 0.0273
Mycobacterium tuberculosis Conserved protein 0.0112 0.0267 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0015 0.0037
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0248 0.0694 0.231
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0072 0.0142 0.0464
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0047 0.0063 0.0182
Schistosoma mansoni regulator of G protein signaling 0.004 0.004 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0014 0.0034
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Trypanosoma cruzi prolyl endopeptidase 0.1909 0.5899 0.6533
Echinococcus multilocularis cpg binding protein 0.0063 0.0112 0.0124
Onchocerca volvulus 0.0685 0.2062 0.3496
Toxoplasma gondii EGF family domain-containing protein 0.0064 0.0117 0.0193
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0106 0.0247 0.0745
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0079 0.0088
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0096 0.0106
Brugia malayi Cathepsin L-like precursor 0.0982 0.2995 0.2995
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.004 0.0111
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0188 0.0505 0.0559
Schistosoma mansoni notch 0.0064 0.0118 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Brugia malayi prolyl oligopeptidase family protein 0.0224 0.0619 0.0619
Plasmodium vivax unspecified product 0.0298 0.0849 0.2826
Schistosoma mansoni cathepsin s 0.0298 0.0849 0.094
Brugia malayi hypothetical protein 0.0056 0.0091 0.0091
Onchocerca volvulus Peroxidase homolog 0.0671 0.2019 0.3423
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0248 0.0694 0.2115
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.2142 0.237
Entamoeba histolytica hypothetical protein 0.0248 0.0694 0.231
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0022 0.0058
Schistosoma mansoni axis inhibition protein axin 0.004 0.004 0.0044
Loa Loa (eye worm) hypothetical protein 0.0479 0.1418 0.1418
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0041 0.0046
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0536 0.1598 0.177
Brugia malayi Cytochrome P450 family protein 0.0056 0.0091 0.0091
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0092 0.0205 0.0227
Onchocerca volvulus Chorion peroxidase homolog 0.0671 0.2019 0.3423
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0106 0.0247 0.0814
Loa Loa (eye worm) hypothetical protein 0.0248 0.0694 0.0694
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2906 0.9027 1
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.005 0.0072 0.0231
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.005 0.0072 0.008
Trypanosoma cruzi calmodulin, putative 0.0106 0.0247 0.027
Brugia malayi Trypsin-like protease protein 5 0.0115 0.0276 0.0276
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.005 0.0072 0.0077
Loa Loa (eye worm) MH2 domain-containing protein 0.006 0.0104 0.0104
Mycobacterium ulcerans Sir2-like regulatory protein 0.0034 0.0022 0.0068
Echinococcus granulosus calpain A 0.071 0.2142 0.2373
Leishmania major protein kinase, putative 0.0106 0.0248 0.0416
Brugia malayi Proteasome A-type and B-type family protein 0.0161 0.042 0.042
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.0267 0.1113
Onchocerca volvulus 0.0671 0.2019 0.3423
Schistosoma mansoni lamin 0.0227 0.0626 0.0694
Toxoplasma gondii aspartyl protease ASP3 0.0321 0.0923 0.156
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Echinococcus multilocularis cathepsin L 0.0248 0.0694 0.0769
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.107 0.3271 0.5544
Schistosoma mansoni neuronal calcium sensor 0.0106 0.0247 0.0273
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0047 0.0063 0.0182
Echinococcus multilocularis caspase 8 0.0172 0.0456 0.0505
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.3217 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0058 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Loa Loa (eye worm) hypothetical protein 0.0057 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0685 0.2062 0.2062
Loa Loa (eye worm) hypothetical protein 0.0087 0.0189 0.0189
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0248 0.0694 0.231
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Schistosoma mansoni hypothetical protein 0.0032 0.0017 0.0018
Trypanosoma brucei centrin-3 0.0106 0.0247 0.0413
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0248 0.0694 0.0769
Plasmodium falciparum thioredoxin reductase 0.0188 0.0505 0.1677
Echinococcus granulosus dna polymerase kappa 0.0061 0.0108 0.012
Plasmodium vivax thioredoxin reductase, putative 0.0542 0.1616 0.5389
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0079 0.0084
Onchocerca volvulus 0.0227 0.0626 0.1062
Trypanosoma cruzi cruzipain precursor, putative 0.1079 0.3299 0.3653
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0132 0.0329 0.1088
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.005 0.0074 0.0074
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.005 0.0072 0.008
Echinococcus granulosus enteropeptidase 0.0115 0.0276 0.0305
Plasmodium falciparum importin beta, putative 0.0085 0.0183 0.0602
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0188 0.0505 0.0851
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0775 0.2346 0.3974
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0982 0.2995 0.2995
Toxoplasma gondii cathepsin CPC2 0.0248 0.0694 0.1172
Schistosoma mansoni gabp alpha 0.0146 0.0374 0.0414
Brugia malayi Cytochrome P450 family protein 0.0107 0.025 0.025
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0213 0.0585 0.0987
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0062 0.0069
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0372 0.1081 0.1198
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0047 0.0063 0.0199
Schistosoma mansoni memapsin-2 (A01 family) 0.0492 0.1458 0.1616
Plasmodium vivax aspartyl protease, putative 0.0321 0.0923 0.3075
Echinococcus granulosus glycogen phosphorylase 0.0109 0.0259 0.0287
Plasmodium vivax serine-repeat antigen (SERA) 0.0248 0.0694 0.231
Brugia malayi Cathepsin L-like precursor 0.0982 0.2995 0.2995
Loa Loa (eye worm) hypothetical protein 0.007 0.0135 0.0135
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0108 0.0116
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0248 0.0694 0.231
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0267 0.088
Brugia malayi cytochrome P450 0.0029 0.0006 0.0006
Trichomonas vaginalis calmodulin, putative 0.0107 0.0251 0.0759
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0161 0.042 0.0706
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Brugia malayi Papain family cysteine protease containing protein 0.0248 0.0694 0.0694
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0188 0.0505 0.0559
Echinococcus multilocularis peroxidasin 0.0671 0.2019 0.2236
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0247 0.0745
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0212 0.0232
Brugia malayi prolyl oligopeptidase family protein 0.0311 0.0892 0.0892
Brugia malayi Pepsin A precursor 0.0056 0.0091 0.0091
Trypanosoma cruzi metacaspase 5, putative 0.0172 0.0456 0.0502
Echinococcus granulosus cathepsin l1 0.0982 0.2995 0.3318
Trypanosoma cruzi cysteine proteinase, putative 0.0546 0.1627 0.18
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.004 0.0044
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0183 0.0305
Plasmodium falciparum plasmepsin III 0.0056 0.0091 0.0293
Brugia malayi mbt repeat family protein 0.005 0.0074 0.0074
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0306 0.0513
Entamoeba histolytica glutamate synthase beta subunit, putative 0.005 0.0072 0.0231
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0146 0.0373 0.0413
Echinococcus granulosus protein jagged 2 0.0064 0.0117 0.013
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0074 0.0082
Giardia lamblia Cathepsin B precursor 0.0248 0.0694 0.2115
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0168 0.0442 0.0442
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0248 0.0694 0.0769
Trypanosoma cruzi centrin-3 0.0106 0.0247 0.027
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0034 0.0022 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0267 0.0806
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0224 0.0619 0.0686
Schistosoma mansoni hypothetical protein 0.0322 0.0925 0.1025
Schistosoma mansoni calpain C (C02 family) 0.071 0.2142 0.2373
Brugia malayi EGF-like domain containing protein 0.0064 0.0117 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0248 0.0694 0.2115
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0061 0.0108 0.0196
Entamoeba histolytica cysteine protease, putative 0.0248 0.0694 0.231
Echinococcus granulosus neurogenic locus notch protein 4 0.0064 0.0117 0.013
Toxoplasma gondii histone deacetylase SIR2-like 0.0034 0.0022 0.0032
Schistosoma mansoni glutamate synthase 0.005 0.0072 0.008
Loa Loa (eye worm) hypothetical protein 0.0224 0.0619 0.0619
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0034 0.0022 0.0063
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0188 0.0505 0.2132
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0029 0.0006 0.0005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0063 0.0113 0.0121
Schistosoma mansoni hypothetical protein 0.0098 0.0222 0.0246
Echinococcus granulosus cathepsin b 0.2906 0.9027 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0132 0.0329 0.0996
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.0163 0.0489
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0133 0.0396
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Loa Loa (eye worm) cytochrome P450 family protein 0.0107 0.025 0.025
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.3628
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0022 0.0058
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0234 0.0234
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.005 0.0072 0.0211
Plasmodium falciparum ferrodoxin reductase-like protein 0.005 0.0072 0.0231
Trypanosoma brucei calpain-like protein, putative 0.071 0.2142 0.3628
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Leishmania major cathepsin L-like protease 0.1079 0.3299 0.5591
Trypanosoma brucei centrin, putative 0.0106 0.0247 0.0413
Schistosoma mansoni calmodulin 0.0106 0.0247 0.0273
Schistosoma mansoni cpg binding protein 0.0063 0.0112 0.0124
Trichomonas vaginalis DNA polymerase eta, putative 0.0061 0.0108 0.032
Echinococcus multilocularis Mastin 0.0115 0.0276 0.0305
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0248 0.0694 0.2115
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.005 0.0072 0.008
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0115 0.0276 0.0305
Trichomonas vaginalis calcineurin B subunit, putative 0.0106 0.0247 0.0745
Toxoplasma gondii histone deacetylase SIR2 0.0034 0.0022 0.0032
Echinococcus multilocularis calpain 7 (C02 family) 0.071 0.2142 0.2373
Loa Loa (eye worm) calpain family protein 1 0.1883 0.5817 0.5817
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.0585 0.1781
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0072 0.0142 0.0154
Plasmodium falciparum centrin-1 0.0106 0.0247 0.0814
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0029 0.0006 0.0003
Plasmodium falciparum plasmepsin V 0.0056 0.0091 0.0293
Schistosoma mansoni peroxidasin 0.0671 0.2019 0.2236
Entamoeba histolytica deoxycytidyl transferase, putative 0.0061 0.0108 0.035
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Loa Loa (eye worm) hypothetical protein 0.026 0.0732 0.0732
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0079 0.0129
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.004 0.0044
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0034 0.0022 0.0032
Echinococcus multilocularis glutamate synthase 0.005 0.0072 0.008
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.004 0.004
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.005 0.0072 0.0211
Trypanosoma cruzi calmodulin, putative 0.0106 0.0247 0.027
Leishmania major DNA polymerase eta, putative 0.0061 0.0108 0.0178
Echinococcus granulosus glycogen phosphorylase 0.0109 0.0259 0.0287
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0108 0.0178
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0311 0.0892 0.1507
Schistosoma mansoni hypothetical protein 0.0911 0.277 0.3069
Echinococcus multilocularis Glycosyl transferase, family 35 0.0109 0.0259 0.0287
Loa Loa (eye worm) hypothetical protein 0.0068 0.013 0.013
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.005 0.0072 0.008
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0106 0.0247 0.027
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.005 0.0072 0.0117
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0063 0.0113 0.0366
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0267 0.0295
Loa Loa (eye worm) hypothetical protein 0.0213 0.0585 0.0585
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0248 0.0694 0.231
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.0267 0.0447
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0306 0.0339
Brugia malayi MH2 domain containing protein 0.006 0.0104 0.0104
Schistosoma mansoni gamma-secretase subunit aph-1 0.0243 0.0676 0.0749
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.005 0.0072 0.008
Brugia malayi Peptidase family M13 containing protein 0.0092 0.0205 0.0205
Loa Loa (eye worm) MBCTL1 0.0057 0.0096 0.0096
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0079 0.0163 0.0181
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0311 0.0344
Entamoeba histolytica disulphide oxidoreductase, putative 0.005 0.0072 0.0231
Giardia lamblia Cathepsin L precursor 0.0248 0.0694 0.2115
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1988 0.6148 0.6811
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0074 0.0082
Echinococcus granulosus calbindin 32 0.0107 0.0251 0.0278
Trypanosoma cruzi major cysteine proteinase, putative 0.0345 0.0999 0.1103
Echinococcus granulosus dnaJ subfamily B 0.0412 0.1206 0.1336
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.004 0.0044
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Brugia malayi Muscle positioning protein 4 0.0064 0.0117 0.0117
Onchocerca volvulus Peroxidasin homolog 0.0671 0.2019 0.3423
Trichomonas vaginalis calcium binding protein, putative 0.0106 0.0247 0.0745
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.0306 0.0306
Entamoeba histolytica calpain large subunit domain III containing protein 0.0497 0.1473 0.4912
Schistosoma mansoni hypothetical protein 0.0032 0.0017 0.0018
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.005 0.0072 0.008
Echinococcus multilocularis cathepsin L cysteine protease 0.0982 0.2995 0.3318
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.004 0.0044
Loa Loa (eye worm) animal heme peroxidase 0.0671 0.2019 0.2019
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0248 0.0694 0.2115
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0282 0.0472
Loa Loa (eye worm) cathepsin B 0.107 0.3271 0.3271
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0034 0.0022 0.0025
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0079 0.0088
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0188 0.0505 0.0559
Loa Loa (eye worm) hypothetical protein 0.007 0.0135 0.0135
Echinococcus multilocularis programmed cell death protein 0.0106 0.0247 0.0273
Plasmodium vivax serine-repeat antigen (SERA) 0.0248 0.0694 0.231
Loa Loa (eye worm) Smad1 0.006 0.0104 0.0104
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0311 0.0892 0.0985
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0546 0.1627 0.1803
Trypanosoma brucei NADH dehydrogenase 0.005 0.0072 0.0117
Echinococcus multilocularis thioredoxin glutathione reductase 0.0545 0.1626 0.1801
Mycobacterium ulcerans monoxygenase 0.005 0.0072 0.0282
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.0259 0.0287
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0074 0.0082
Leishmania major GTP-binding protein, putative 0.0063 0.0113 0.0186
Plasmodium vivax ferrodoxin reductase, putative 0.005 0.0072 0.0231
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.0267 0.0502
Brugia malayi Cathepsin L-like precursor 0.0982 0.2995 0.2995
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0061 0.0108 0.032
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0161 0.042 0.0461
Trypanosoma brucei SIR2-like protein 4, putative 0.0034 0.0022 0.0032
Brugia malayi calpain family protein 1 0.1883 0.5817 0.5817
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0106 0.0247 0.027
Entamoeba histolytica calmodulin, putative 0.0106 0.0247 0.0814
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Echinococcus granulosus TGF beta signal transducer SmadC 0.006 0.0104 0.0115
Onchocerca volvulus 0.0982 0.2995 0.5078
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0106 0.0247 0.0273
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0091 0.0361
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.005 0.0072 0.0211
Trypanosoma cruzi trypanothione reductase, putative 0.0542 0.1616 0.1787
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0248 0.0694 0.2115
Trichomonas vaginalis myosin light chain 1, putative 0.0106 0.0247 0.0745
Schistosoma mansoni slit 0.0064 0.0117 0.013
Brugia malayi hypothetical protein 0.0156 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0188 0.0505 0.0851
Trypanosoma cruzi metacaspase, putative 0.0172 0.0456 0.0502
Toxoplasma gondii selenide, water dikinase 0.005 0.0072 0.0117
Brugia malayi Cadherin domain containing protein 0.0064 0.0117 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0082 0.0241
Loa Loa (eye worm) hypothetical protein 0.1909 0.5899 0.5899
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0267 0.0295
Echinococcus multilocularis geminin 0.0179 0.0476 0.0528
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0106 0.0248 0.0416
Echinococcus multilocularis calumenin 0.0107 0.0251 0.0278
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0172 0.0456 0.0768
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.004 0.0044
Echinococcus multilocularis neurogenic locus protein delta 0.0064 0.0117 0.013
Brugia malayi MH1 domain containing protein 0.0033 0.002 0.002
Schistosoma mansoni neuronal calcium sensor 0.0106 0.0247 0.0273
Entamoeba histolytica cysteine protease, putative 0.0248 0.0694 0.231
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0047 0.0063 0.0101
Leishmania major hypothetical protein, conserved 0.005 0.0072 0.0117
Echinococcus granulosus calpain A 0.199 0.6153 0.6816
Echinococcus multilocularis acylamino acid releasing enzyme 0.0224 0.0619 0.0686
Giardia lamblia Encystation-specific protease 0.0248 0.0694 0.2115
Mycobacterium ulcerans ferredoxin reductase 0.005 0.0072 0.0282
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Echinococcus multilocularis EF hand domain containing family member A2 0.0106 0.0247 0.0273
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.237
Plasmodium vivax unspecified product 0.0248 0.0694 0.231
Echinococcus granulosus Smad4 0.006 0.0104 0.0115
Trypanosoma cruzi cysteine peptidase, putative 0.1079 0.3299 0.3653
Brugia malayi CXXC zinc finger family protein 0.0059 0.0102 0.0102
Giardia lamblia Cathepsin L precursor 0.0248 0.0694 0.2115
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0072 0.0077
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0106 0.0247 0.027
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0063 0.0113 0.0125
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.005 0.0072 0.008
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0161 0.042 0.0461
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.3628
Leishmania major calmodulin, putative 0.0106 0.0247 0.0413
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.0259 0.0854
Brugia malayi prolyl oligopeptidase family protein 0.0536 0.1598 0.1598
Brugia malayi Blistered cuticle protein 3 0.0671 0.2019 0.2019
Plasmodium falciparum glutathione reductase 0.0188 0.0505 0.1677
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.0259 0.0854
Trichomonas vaginalis centrin, putative 0.0106 0.0247 0.0745
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0248 0.0694 0.231
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Entamoeba histolytica cysteine proteinase, putative 0.0982 0.2995 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.004 0.0111
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0056 0.0091 0.0101
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Brugia malayi notch-like transmembrane receptor 0.0064 0.0117 0.0117
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0775 0.2346 0.5545
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0213 0.0585 0.0645
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Trypanosoma brucei Calpain-like protein 1.2 0.0213 0.0585 0.0987
Echinococcus granulosus cpg binding protein 0.0063 0.0112 0.0124
Entamoeba histolytica cysteine protease, putative 0.0982 0.2995 1
Brugia malayi beta-lactamase family protein 0.0112 0.0267 0.0267
Leishmania major cathepsin L-like protease 0.1079 0.3299 0.5591
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0112
Echinococcus multilocularis axis inhibition protein axin 0.004 0.004 0.0044
Trypanosoma cruzi kinesin, putative 0.0497 0.1473 0.1629
Loa Loa (eye worm) hypothetical protein 0.0068 0.013 0.013
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.005 0.0072 0.0077
Echinococcus granulosus calpain 0.071 0.2142 0.2373
Echinococcus multilocularis fibropellin Ia 0.0064 0.0117 0.013
Echinococcus granulosus endothelin converting enzyme 1 0.0092 0.0205 0.0227
Onchocerca volvulus 0.0098 0.0222 0.0377
Loa Loa (eye worm) programmed cell death protein 6 0.0107 0.0251 0.0251
Onchocerca volvulus 0.0115 0.0276 0.0467
Entamoeba histolytica prolyl oligopeptidase family protein 0.0224 0.0619 0.2058
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0079 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0456 0.1385
Leishmania major DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0456 0.1385
Plasmodium vivax SET domain protein, putative 0.0124 0.0306 0.1011
Entamoeba histolytica hypothetical protein 0.0037 0.0032 0.0097
Loa Loa (eye worm) calpain D 0.0213 0.0585 0.0585
Giardia lamblia Proteasome subunit beta type 2 0.0047 0.0063 0.0182
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0132 0.0329 0.0364
Echinococcus granulosus peroxidasin 0.0671 0.2019 0.2236
Plasmodium falciparum calpain 0.0213 0.0585 0.1945
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Mycobacterium tuberculosis Probable oxidoreductase 0.1375 0.4226 0.8131
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0072 0.0211
Echinococcus granulosus protein jagged 1 0.0064 0.0117 0.013
Giardia lamblia Sirtuin type 2 0.0034 0.0022 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.0546 0.1627 0.5428
Toxoplasma gondii cathepsin CPL 0.0982 0.2995 0.5075
Echinococcus multilocularis GA binding protein alpha chain 0.0146 0.0374 0.0414
Echinococcus multilocularis protein jagged 1 0.0064 0.0117 0.013
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0248 0.0694 0.231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0082 0.0241
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0047 0.0063 0.007
Onchocerca volvulus 0.0982 0.2995 0.5078
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0106 0.0248 0.0819
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0072 0.0211
Leishmania major centrin, putative 0.0106 0.0247 0.0413
Echinococcus granulosus GA binding protein alpha chain 0.0146 0.0374 0.0414
Brugia malayi Papain family cysteine protease containing protein 0.0546 0.1627 0.1627
Loa Loa (eye worm) aspartyl protease 6 0.0056 0.0091 0.0091
Echinococcus granulosus cathepsin l cysteine peptidase 0.0982 0.2995 0.3318
Schistosoma mansoni hypothetical protein 0.0412 0.1206 0.1336
Loa Loa (eye worm) hypothetical protein 0.0109 0.0259 0.0259
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.004 0.0044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Plasmodium vivax aspartyl protease, putative 0.0321 0.0923 0.3075
Echinococcus multilocularis calpain 5 0.071 0.2142 0.2373
Entamoeba histolytica cysteine protease, putative 0.0248 0.0694 0.231
Giardia lamblia Cysteine protease 0.0248 0.0694 0.2115
Echinococcus multilocularis caspase 0.0321 0.0921 0.1021
Schistosoma mansoni cathepsin B (C01 family) 0.0248 0.0694 0.0769
Giardia lamblia DINP protein human, muc B family 0.0061 0.0108 0.032
Brugia malayi Ets-domain containing protein 0.0146 0.0374 0.0374
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.004 0.004
Brugia malayi Animal haem peroxidase family protein 0.0671 0.2019 0.2019
Brugia malayi Animal haem peroxidase family protein 0.0671 0.2019 0.2019
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0072 0.0142 0.0157
Brugia malayi hypothetical protein 0.0056 0.0091 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.004 0.0111
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0041 0.0041
Echinococcus multilocularis calcium uptake protein 1 0.0107 0.0251 0.0278
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.0267 0.0502
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Onchocerca volvulus Slit protein homolog 0.0064 0.0117 0.0199
Schistosoma mansoni ran 0.0063 0.0113 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0248 0.0694 0.2115
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0234 0.0234
Trypanosoma cruzi cysteine peptidase, putative 0.1079 0.3299 0.3653
Giardia lamblia Alanyl dipeptidyl peptidase 0.0224 0.0619 0.1884
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0079 0.0163 0.0489
Echinococcus granulosus cysteine protease 0.0546 0.1627 0.1803
Leishmania major cathepsin L-like protease 0.0982 0.2995 0.5075
Brugia malayi EF hand family protein 0.0106 0.0247 0.0247
Schistosoma mansoni cathepsin F (C01 family) 0.0982 0.2995 0.3318
Trypanosoma cruzi NADH dehydrogenase, putative 0.005 0.0072 0.0077
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0132 0.0329 0.0361
Brugia malayi cathepsin L-like cysteine proteinase 0.0248 0.0694 0.0694
Echinococcus granulosus dna polymerase eta 0.0061 0.0108 0.012
Schistosoma mansoni neprilysin-2 (M13 family) 0.0047 0.0062 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0072 0.0211
Mycobacterium leprae probable zinc metalloprotease 0.0092 0.0205 0.0472
Toxoplasma gondii calmodulin CAM1 0.0107 0.0251 0.0421
Echinococcus multilocularis centrin 2 0.0106 0.0247 0.0273
Echinococcus granulosus Mastin 0.0115 0.0276 0.0305
Echinococcus multilocularis smad 0.006 0.0104 0.0115
Schistosoma mansoni hypothetical protein 0.005 0.0072 0.008
Loa Loa (eye worm) MH2 domain-containing protein 0.0879 0.2673 0.2673
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0053 0.0082 0.0134
Entamoeba histolytica cysteine proteinase, putative 0.0546 0.1627 0.5428
Plasmodium vivax proteasome subunit beta type-2, putative 0.0047 0.0063 0.0199
Schistosoma mansoni Smad4 0.006 0.0104 0.0115
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0213 0.0585 0.0645
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0248 0.0694 0.2115
Plasmodium vivax centrin-1, putative 0.0106 0.0247 0.0814
Plasmodium falciparum serine repeat antigen 4 0.0248 0.0694 0.231
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.0259 0.0287
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Echinococcus granulosus prolyl endopeptidase 0.1909 0.5899 0.6535
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0048 0.0137
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0108 0.0178
Brugia malayi proteasome subunit beta type 2 0.0047 0.0063 0.0063
Plasmodium falciparum peptidase, putative 0.0224 0.0619 0.2058
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0034 0.0022 0.0025
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.005 0.0072 0.0231
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0311 0.1301
Toxoplasma gondii hypothetical protein 0.0224 0.0619 0.1044
Schistosoma mansoni rab 0.0106 0.0247 0.0273
Loa Loa (eye worm) hypothetical protein 0.1669 0.5148 0.5148
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0034 0.0022 0.0063
Entamoeba histolytica cysteine protease, putative 0.0248 0.0694 0.231
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0072 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0546 0.1627 0.4969
Onchocerca volvulus Huntingtin homolog 0.0127 0.0313 0.053
Mycobacterium tuberculosis Conserved protein 0.0112 0.0267 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0224 0.0619 0.1884
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0536 0.1598 0.2708
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0851
Onchocerca volvulus 0.1172 0.3591 0.6088
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0188 0.0505 0.0851
Trypanosoma cruzi cysteine protease, putative 0.0546 0.1627 0.18
Echinococcus multilocularis transmembrane protease serine 3 0.0115 0.0276 0.0305
Mycobacterium ulcerans hypothetical protein 0.005 0.0072 0.0282
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Plasmodium vivax plasmepsin V, putative 0.0056 0.0091 0.0293
Mycobacterium tuberculosis Probable dehydrogenase 0.1237 0.3793 0.7297
Plasmodium vivax vivapain-1 0.0546 0.1627 0.5428
Echinococcus multilocularis neurogenic locus notch protein 0.0064 0.0117 0.013
Schistosoma mansoni z-protein (S1r protein) 0.004 0.004 0.0044
Toxoplasma gondii centrin 0.0106 0.0247 0.0413
Brugia malayi programmed cell death protein 6 0.0106 0.0247 0.0247
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Trichomonas vaginalis glutathione reductase, putative 0.0188 0.0505 0.1535
Schistosoma mansoni regulator of G protein signaling 0.004 0.004 0.0044
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0056 0.0091 0.0091
Trypanosoma cruzi target of rapamycin kinase 3 0.0042 0.0048 0.005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0851
Trypanosoma brucei calpain-like protein, putative 0.071 0.2142 0.3628
Giardia lamblia High cysteine protein 0.0064 0.0117 0.0348
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0213 0.0585 0.0645
Loa Loa (eye worm) animal heme peroxidase 0.0671 0.2019 0.2019
Trypanosoma brucei calpain, putative 0.0213 0.0585 0.0987
Schistosoma mansoni caspase-7 (C14 family) 0.034 0.0982 0.1088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0079 0.0163 0.0177
Echinococcus multilocularis Smad4 0.006 0.0104 0.0115
Echinococcus multilocularis apoptotic protease activating factor 1 0.0168 0.0442 0.049
Brugia malayi EGF-like domain containing protein 0.0064 0.0117 0.0117
Mycobacterium ulcerans proteasome PrcB 0.0161 0.042 0.1767
Trichomonas vaginalis calpain, putative 0.0213 0.0585 0.1781
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0032 0.0036
Brugia malayi calpain D 0.0213 0.0585 0.0585
Leishmania major hypothetical protein, conserved 0.005 0.0072 0.0117
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0079 0.0163 0.0302
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0347 0.0385
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0032 0.0036
Plasmodium falciparum plasmepsin I 0.0056 0.0091 0.0293
Loa Loa (eye worm) hypothetical protein 0.0056 0.0091 0.0091
Schistosoma mansoni Mername-AA248 (C02 family) 0.071 0.2142 0.2373
Loa Loa (eye worm) intermediate filament protein 0.0227 0.0626 0.0626
Echinococcus multilocularis endothelin converting enzyme 1 0.0092 0.0205 0.0227
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0982 0.2995 1
Mycobacterium tuberculosis Probable peptidase 0.0775 0.2346 0.4508
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0188 0.0505 0.1677
Brugia malayi Calcium binding EGF domain containing protein 0.0064 0.0117 0.0117
Entamoeba histolytica hypothetical protein 0.004 0.004 0.0123
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Trypanosoma brucei cysteine peptidase, putative 0.0213 0.0585 0.0987
Brugia malayi Eukaryotic aspartyl protease family protein 0.0056 0.0091 0.0091
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Loa Loa (eye worm) hypothetical protein 0.007 0.0135 0.0135
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.005 0.0072 0.0127
Brugia malayi hypothetical protein 0.0037 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0056 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0179 0.0476 0.0528
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0213 0.0585 0.0645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0015 0.0037
Schistosoma mansoni glycogen phosphorylase 0.0109 0.0259 0.0287
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.0311 0.0344
Brugia malayi Fli-1 protein 0.0443 0.1306 0.1306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0546 0.1627 0.2754
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0306 0.0339
Schistosoma mansoni chromatin regulatory protein sir2 0.0132 0.0329 0.0364
Entamoeba histolytica cysteine protease, putative 0.0248 0.0694 0.231
Schistosoma mansoni hypothetical protein 0.0064 0.0117 0.013
Echinococcus granulosus calpain 7 C02 family 0.071 0.2142 0.2373
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0106 0.0247 0.0273
Brugia malayi cytoplasmic intermediate filament protein 0.0121 0.0297 0.0297
Brugia malayi glutamate synthase 0.005 0.0072 0.0072
Echinococcus granulosus lamin 0.0227 0.0626 0.0694
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0585 0.1781
Echinococcus granulosus mothers against decapentaplegic 5 0.006 0.0104 0.0115
Plasmodium falciparum glutathione reductase 0.0542 0.1616 0.5389
Leishmania major hypothetical protein, unknown function 0.0213 0.0585 0.0987
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0248 0.0694 0.0694
Brugia malayi Cathepsin L-like cysteine proteinase 0.0685 0.2062 0.2062
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0347 0.0385
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0047 0.0063 0.0066
Toxoplasma gondii proteasome subunit beta type, putative 0.0161 0.042 0.0706
Brugia malayi calcium-binding protein 0.0106 0.0247 0.0247
Brugia malayi GCC2 and GCC3 family protein 0.0064 0.0117 0.0117
Trichomonas vaginalis ran, putative 0.0063 0.0113 0.0335
Brugia malayi TAR-binding protein 0.0124 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0092 0.0205 0.0205
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.004 0.0111
Giardia lamblia Cysteine protease 0.0248 0.0694 0.2115
Trypanosoma brucei prolyl oligopeptidase, putative 0.0775 0.2346 0.3974
Entamoeba histolytica cysteine proteinase, putative 0.0982 0.2995 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0188 0.0505 0.1677
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0156 0.0405 0.0405
Brugia malayi Papain family cysteine protease containing protein 0.0248 0.0694 0.0694
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0298 0.0849 0.0849
Onchocerca volvulus 0.0115 0.0276 0.0467
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.0267 0.0502
Trypanosoma brucei Aph-1 protein, putative 0.0095 0.0212 0.0354
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0064 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0248 0.0694 0.2115
Trichomonas vaginalis calcium binding proteins, putative 0.0106 0.0247 0.0745
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0032 0.0036
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Brugia malayi Animal haem peroxidase family protein 0.0671 0.2019 0.2019
Loa Loa (eye worm) cytochrome P450 0.0029 0.0006 0.0006
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0042 0.0048 0.0076
Mycobacterium ulcerans hypothetical protein 0.0115 0.0276 0.1151
Schistosoma mansoni notch 0.0064 0.0117 0.013
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.005 0.0072 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.004 0.0111
Brugia malayi EGF-like domain containing protein 0.0064 0.0117 0.0117
Brugia malayi Animal haem peroxidase family protein 0.0671 0.2019 0.2019
Schistosoma mansoni smad1 5 8 and 0.006 0.0104 0.0115
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0029 0.0006 0.0005
Schistosoma mansoni cathepsin S (C01 family) 0.0248 0.0694 0.0769
Brugia malayi EF hand family protein 0.0107 0.0251 0.0251
Trypanosoma cruzi cysteine peptidase, putative 0.1079 0.3299 0.3653
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0034 0.0022 0.0021
Plasmodium falciparum serine repeat antigen 1 0.0248 0.0694 0.231
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0042 0.0048 0.0076
Schistosoma mansoni cpg binding protein 0.0059 0.0102 0.0113
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0311 0.0892 0.1507
Echinococcus granulosus caspase 3 0.0148 0.0381 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Onchocerca volvulus Cathepsin L homolog 0.0248 0.0694 0.1177
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0188 0.0505 0.0851
Giardia lamblia Cathepsin B precursor 0.0248 0.0694 0.2115
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0079 0.0088
Chlamydia trachomatis glycogen phosphorylase 0.0109 0.0259 0.4309
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0132 0.0329 0.0996
Schistosoma mansoni notch 0.0064 0.0117 0.013
Loa Loa (eye worm) EF hand family protein 0.0106 0.0247 0.0247
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0311 0.0344
Brugia malayi Calmodulin-like protein 0.0106 0.0247 0.0247
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0053 0.0082 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0456 0.1385
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0224 0.0619 0.1884
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0556
Loa Loa (eye worm) notch protein 0.0064 0.0117 0.0117
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Plasmodium falciparum proteasome subunit beta type-5 0.0161 0.042 0.1392
Onchocerca volvulus 0.0982 0.2995 0.5078
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1237 0.3793 0.7297
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0063 0.0113 0.0186
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0311 0.1301
Trypanosoma brucei Calpain-like protein 1.1 0.0213 0.0585 0.0987
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.237
Echinococcus multilocularis calmodulin 0.0106 0.0247 0.0273
Echinococcus granulosus thioredoxin glutathione reductase 0.0545 0.1626 0.1801
Trypanosoma brucei proteasome beta 6 subunit 0.0072 0.0142 0.0235
Echinococcus granulosus chromatin regulatory protein sir2 0.0132 0.0329 0.0364
Brugia malayi Importin beta-1 subunit 0.0085 0.0183 0.0183
Plasmodium vivax hypothetical protein, conserved 0.0172 0.0456 0.1513
Entamoeba histolytica hypothetical protein 0.004 0.004 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0063 0.0113 0.0335
Schistosoma mansoni hypothetical protein 0.0069 0.0133 0.0148
Echinococcus multilocularis calpain A 0.199 0.6153 0.6816
Brugia malayi hypothetical protein 0.0127 0.0313 0.0313
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0248 0.0694 0.231
Echinococcus multilocularis expressed protein 0.077 0.233 0.2581
Echinococcus multilocularis cysteine protease 0.0982 0.2995 0.3318
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0106 0.0247 0.0413
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0224 0.0619 0.1044
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0248 0.0694 0.231
Giardia lamblia Cathepsin L precursor 0.0248 0.0694 0.2115
Trypanosoma cruzi NADH dehydrogenase, putative 0.005 0.0072 0.0077
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0347 0.0385
Trypanosoma cruzi centrin, putative 0.0106 0.0247 0.027
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.0267 0.0502
Brugia malayi Cathepsin L-like precursor 0.0982 0.2995 0.2995
Brugia malayi gamma-secretase subunit aph-1 0.0243 0.0676 0.0676
Trypanosoma brucei trypanothione reductase 0.0542 0.1616 0.2735
Toxoplasma gondii aspartyl protease 0.0056 0.0091 0.0149
Schistosoma mansoni cathepsin D (A01 family) 0.0366 0.1062 0.1177
Toxoplasma gondii EFHC1, putative 0.0106 0.0247 0.0413
Schistosoma mansoni hypothetical protein 0.0213 0.0585 0.0648
Loa Loa (eye worm) proteasome subunit beta type 2 0.0047 0.0063 0.0063
Loa Loa (eye worm) Notch2 0.0064 0.0117 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0079 0.0233
Schistosoma mansoni hypothetical protein 0.0064 0.0117 0.013
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0685 0.2062 0.6301
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1375 0.4226 1
Echinococcus multilocularis axis inhibition protein axin 0.004 0.004 0.0044
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0585 0.1781
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0248 0.0694 0.2115
Loa Loa (eye worm) hypothetical protein 0.1386 0.426 0.426
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0248 0.0694 0.0769
Trypanosoma cruzi metacaspase, putative 0.0172 0.0456 0.0502
Echinococcus granulosus geminin 0.0179 0.0476 0.0528
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0224 0.0619 0.1884
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Loa Loa (eye worm) hypothetical protein 0.0248 0.0694 0.0694
Trypanosoma brucei antigen, putative 0.071 0.2142 0.3628
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Echinococcus multilocularis neurogenic locus notch protein 4 0.0064 0.0117 0.013
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0072 0.0142 0.0235
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2906 0.9027 1
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.004 0.0044
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.005 0.0072 0.0231
Brugia malayi hypothetical protein 0.0087 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0032 0.0017 0.0017
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0053 0.0082 0.0134
Leishmania major oligopeptidase b 0.0775 0.2346 0.3974
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Echinococcus granulosus cathepsin L cysteine protease 0.0546 0.1627 0.1803
Echinococcus multilocularis hypothetical protein 0.071 0.2142 0.2373
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0267 0.0806
Loa Loa (eye worm) hypothetical protein 0.0124 0.0306 0.0306
Entamoeba histolytica Ran family GTPase 0.0063 0.0113 0.0366
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0311 0.0892 0.1507
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0091 0.0091
Echinococcus granulosus microtubule associated protein 2 0.1424 0.4378 0.4851
Schistosoma mansoni reticulocalbin 0.0107 0.0251 0.0278
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0311 0.0892 0.1507
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Echinococcus granulosus lamin dm0 0.0227 0.0626 0.0694
Mycobacterium ulcerans glutamate synthase subunit beta 0.005 0.0072 0.0282
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.0311 0.0522
Schistosoma mansoni mitochondrial solute carrier 0.0106 0.0247 0.0273
Echinococcus multilocularis microtubule associated protein 2 0.1424 0.4378 0.4851
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0982 0.2995 0.9155
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0048 0.0137
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0267 0.0292
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0213 0.0585 0.0645
Echinococcus granulosus glycoprotein Antigen 5 0.0115 0.0276 0.0305
Brugia malayi Flap endonuclease-1 0.0028 0.0003 0.0003
Schistosoma mansoni regulator of G protein signaling 0.004 0.004 0.0044
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0096 0.0106
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.004 0.004
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0248 0.0694 0.231
Giardia lamblia Hypothetical protein 0.0248 0.0694 0.2115
Mycobacterium ulcerans zinc metalloprotease 0.0092 0.0205 0.085
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0298 0.0849 0.0849
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.3628
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0091 0.0097
Echinococcus multilocularis proteasome (prosome, macropain) 0.0161 0.042 0.0465
Echinococcus multilocularis mothers against decapentaplegic 5 0.006 0.0104 0.0115
Echinococcus multilocularis calmodulin 0.0106 0.0247 0.0273
Plasmodium vivax glutathione reductase, putative 0.0542 0.1616 0.5389
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0064 0.0117 0.013
Schistosoma mansoni cathepsin C 0.0248 0.0694 0.0769
Onchocerca volvulus 0.0107 0.0251 0.0426
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0079 0.0233
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0619 0.0682
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0546 0.1627 0.18
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.005 0.0072 0.0282
Trypanosoma cruzi 20S proteasome subunit 0.0047 0.0063 0.0066
Brugia malayi Thioredoxin reductase 0.0542 0.1616 0.1616
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0112
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0248 0.0694 0.0769
Giardia lamblia Cathepsin L precursor 0.0248 0.0694 0.2115
Echinococcus granulosus axis inhibition protein axin 0.004 0.004 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0556
Plasmodium falciparum serine repeat antigen 5 0.0248 0.0694 0.231
Loa Loa (eye worm) glutathione reductase 0.0542 0.1616 0.1616
Brugia malayi cathepsin F-like cysteine proteinase 0.0298 0.0849 0.0849
Leishmania major cathepsin L-like protease 0.0982 0.2995 0.5075
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0022 0.0063
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0172 0.0456 0.0505
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0213 0.0585 0.0987
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.0267 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0619 0.0682
Leishmania major cytochrome p450-like protein 0.0056 0.0091 0.0148
Plasmodium vivax hypothetical protein, conserved 0.0107 0.0251 0.0829
Giardia lamblia Cathepsin L-like protease 0.0248 0.0694 0.2115
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1684 0.5196 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Loa Loa (eye worm) RGS-3 protein 0.004 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Schistosoma mansoni cell polarity protein 0.0064 0.0117 0.013
Onchocerca volvulus 0.0056 0.0091 0.0154
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0536 0.1598 0.177
Schistosoma mansoni ef hand domain family member A2 0.0106 0.0247 0.0273
Echinococcus granulosus snurportin 1 0.0911 0.277 0.3069
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.005 0.0072 0.0231
Onchocerca volvulus 0.0064 0.0117 0.0199
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0372 0.1081 0.1198
Echinococcus granulosus calmodulin 0.0106 0.0247 0.0273
Brugia malayi Cadherin domain containing protein 0.0064 0.0117 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0048 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0248 0.0694 0.2115
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0248 0.0694 0.0769
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0108 0.0435
Echinococcus granulosus importin subunit beta 1 0.0085 0.0183 0.0203
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Echinococcus multilocularis dna polymerase kappa 0.0061 0.0108 0.012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.237
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1909 0.5899 0.6535
Brugia malayi calpain 7 0.071 0.2142 0.2142
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1988 0.6148 0.6811
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.005 0.0072 0.0157
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0108 0.0108
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.004 0.0044
Schistosoma mansoni calpain-7 (C02 family) 0.072 0.2172 0.2407
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0188 0.0505 0.0556
Trypanosoma brucei centrin, putative 0.0106 0.0247 0.0413
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0074 0.0082
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.0347 0.0347
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.005 0.0072 0.0127
Echinococcus granulosus neural cadherin 0.0064 0.0117 0.013
Schistosoma mansoni hypothetical protein 0.0115 0.0276 0.0305
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0115 0.0276 0.0305
Entamoeba histolytica calpain family cysteine protease, putative 0.0213 0.0585 0.1945
Trypanosoma brucei hypothetical protein 0.0213 0.0585 0.0987
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0267 0.0806
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0003 0.0004
Schistosoma mansoni notch 0.0064 0.0117 0.013
Trypanosoma brucei unspecified product 0.0042 0.0048 0.0076
Trypanosoma cruzi importin beta-1 subunit, putative 0.0069 0.0133 0.0144
Plasmodium vivax importin-beta 2, putative 0.0085 0.0183 0.0602
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0243 0.0676 0.0676
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.005 0.0072 0.008
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0053 0.0082 0.0087
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Schistosoma mansoni calpain-2 (C02 family) 0.0213 0.0585 0.0648
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0124 0.0306 0.0339
Trypanosoma brucei prolyl endopeptidase 0.1909 0.5899 1
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Loa Loa (eye worm) hypothetical protein 0.0106 0.0247 0.0247
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0347 0.0385
Mycobacterium ulcerans beta-lactamase 0.0112 0.0267 0.1113
Schistosoma mansoni centrin 0.0106 0.0247 0.0273
Echinococcus granulosus tar DNA binding protein 0.0124 0.0306 0.0339
Schistosoma mansoni neuronal calcium sensor 0.0106 0.0247 0.0273
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0062 0.0069
Trypanosoma cruzi centrin, putative 0.0106 0.0247 0.027
Entamoeba histolytica cysteine proteinase 1, putative 0.0546 0.1627 0.5428
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0911 0.277 0.277
Giardia lamblia Cysteine protease 0.0248 0.0694 0.2115
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.005 0.0072 0.0117
Mycobacterium ulcerans dehydrogenase 0.005 0.0072 0.0282
Trypanosoma brucei I/6 autoantigen 0.0106 0.0247 0.0413
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.005 0.0072 0.0117
Onchocerca volvulus 0.005 0.0072 0.0123
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0982 0.2995 0.3318
Loa Loa (eye worm) hypothetical protein 0.007 0.0135 0.0135
Loa Loa (eye worm) transcriptional regulator 0.0034 0.0022 0.0022
Leishmania major hypothetical protein, conserved 0.0107 0.0251 0.0421
Brugia malayi transcriptional regulator, Sir2 family protein 0.0034 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0072
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0108 0.0196
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0248 0.0694 0.231
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0132 0.0329 0.1088
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0146 0.0374 0.0374
Leishmania major i/6 autoantigen-like protein 0.0106 0.0247 0.0413
Loa Loa (eye worm) transcriptional regulator 0.0132 0.0329 0.0329
Toxoplasma gondii cytochrome p450 superfamily protein 0.0029 0.0006 0.0005
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0047 0.0064 0.0248
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0106 0.0247 0.0273
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0214 0.0588 0.0651
Echinococcus multilocularis protein jagged 1 0.0064 0.0117 0.013
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0092 0.0205 0.0383
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Loa Loa (eye worm) hypothetical protein 0.0685 0.2062 0.2062
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0079 0.0084
Toxoplasma gondii peptidase family M13 protein 0.0092 0.0205 0.0343
Onchocerca volvulus 0.0106 0.0247 0.0418
Giardia lamblia Cathepsin L precursor 0.0248 0.0694 0.2115
Brugia malayi hypothetical protein 0.0671 0.2019 0.2019
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Leishmania major trypanothione reductase 0.0542 0.1616 0.2735
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0056 0.0091 0.0268
Echinococcus multilocularis GPCR, family 2 0.0032 0.0017 0.0018
Giardia lamblia Cathepsin B precursor 0.107 0.3271 1
Plasmodium vivax aspartyl proteinase, putative 0.0056 0.0091 0.0293
Loa Loa (eye worm) phosphatidylinositol 3 0.0053 0.0082 0.0082
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0188 0.0505 0.0961
Onchocerca volvulus 0.0982 0.2995 0.5078
Leishmania major importin beta-1 subunit, putative 0.0069 0.0133 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0028 0.0074
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Entamoeba histolytica cysteine proteinase, putative 0.0546 0.1627 0.5428
Onchocerca volvulus 0.0064 0.0117 0.0199
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0106 0.0247 0.0814
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.005 0.0072 0.0127
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0072 0.0117
Schistosoma mansoni ap endonuclease 0.0079 0.0163 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0775 0.2346 0.2596
Schistosoma mansoni smad 0.006 0.0104 0.0115
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.005 0.0072 0.0231
Toxoplasma gondii EF hand domain-containing protein 0.0106 0.0247 0.0413
Toxoplasma gondii hypothetical protein 0.0213 0.0585 0.0987
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0267 0.0806
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.005 0.0072 0.0157
Toxoplasma gondii prolyl endopeptidase 0.1909 0.5899 1
Trichomonas vaginalis glutamate synthase, putative 0.005 0.0072 0.0211
Loa Loa (eye worm) calpain family protein 1 0.1386 0.426 0.426
Loa Loa (eye worm) prolyl oligopeptidase 0.0536 0.1598 0.1598
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0079 0.0088
Onchocerca volvulus 0.0124 0.0306 0.0518
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0146 0.0373 0.113
Brugia malayi cathepsin L-like precursor 0.0685 0.2062 0.2062
Schistosoma mansoni smad1 5 8 and 0.006 0.0104 0.0115
Echinococcus multilocularis neurogenic locus protein delta 0.0064 0.0117 0.013
Loa Loa (eye worm) hypothetical protein 0.0115 0.0276 0.0276
Entamoeba histolytica hypothetical protein 0.0037 0.0032 0.0097
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0188 0.0505 0.0851
Onchocerca volvulus Dual oxidase homolog 0.0671 0.2019 0.3423
Echinococcus granulosus sulfide:quinone oxidoreductase 0.005 0.0072 0.008
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0056 0.0091 0.0149
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0047 0.0063 0.007
Brugia malayi EGF-like domain containing protein 0.0064 0.0117 0.0117
Loa Loa (eye worm) proteasome subunit beta type 1 0.0072 0.0142 0.0142
Echinococcus granulosus centrin 2 0.0106 0.0247 0.0273
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Schistosoma mansoni chromatin regulatory protein sir2 0.0146 0.0373 0.0413
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.0267 0.0502
Onchocerca volvulus Huntingtin homolog 0.0127 0.0313 0.053
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0041 0.0046
Echinococcus multilocularis EF hand domain containing family member A2 0.0107 0.0251 0.0278
Brugia malayi transcriptional regulator, Sir2 family protein 0.0034 0.0022 0.0022
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0248 0.0694 0.2115
Onchocerca volvulus Cell death protein 3 homolog 0.034 0.0982 0.1665
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.0347 0.0347
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0248 0.0694 0.0769
Plasmodium vivax NAD-dependent deacetylase, putative 0.0034 0.0022 0.0063
Trypanosoma brucei Calpain-like protein 2 0.0213 0.0585 0.0987
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0079 0.0233
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0064 0.0117 0.0117
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0079 0.0163 0.0271
Brugia malayi Cytochrome P450 family protein 0.0056 0.0091 0.0091
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Echinococcus multilocularis cathepsin b 0.2906 0.9027 1
Loa Loa (eye worm) calpain 5 0.0497 0.1473 0.1473
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0248 0.0694 0.2115
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1237 0.3793 0.7297
Echinococcus multilocularis tumor protein p63 0.1779 0.5491 0.6083
Trypanosoma brucei kinesin, putative 0.0497 0.1473 0.2493
Echinococcus multilocularis glycoprotein Antigen 5 0.0115 0.0276 0.0305
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.005 0.0072 0.0282
Plasmodium falciparum plasmepsin IV 0.0056 0.0091 0.0293
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0064 0.0117 0.013
Plasmodium falciparum metacaspase-like protein 0.0172 0.0456 0.1513
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.005 0.0072 0.0117
Onchocerca volvulus 0.0982 0.2995 0.5078
Schistosoma mansoni septate junction protein 0.0064 0.0117 0.013
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0079 0.0163 0.2097
Trichomonas vaginalis calcineurin B subunit, putative 0.0107 0.0251 0.0759
Trypanosoma cruzi caltractin, putative 0.0106 0.0247 0.027
Loa Loa (eye worm) hypothetical protein 0.0298 0.0849 0.0849
Echinococcus granulosus cathepsin b 0.2906 0.9027 1
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.005 0.0072 0.0282
Loa Loa (eye worm) TAR-binding protein 0.0124 0.0306 0.0306
Brugia malayi calpain family protein 1 0.1883 0.5817 0.5817
Trichomonas vaginalis apoptosis inducing factor, putative 0.005 0.0072 0.0211
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0106 0.0248 0.0271
Plasmodium falciparum serine repeat antigen 8 0.0248 0.0694 0.231
Trypanosoma brucei Component of motile flagella 41 0.0106 0.0247 0.0413
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0072 0.0142 0.0154
Schistosoma mansoni lamin 0.0227 0.0626 0.0694
Giardia lamblia Proteasome subunit beta type 1 0.0072 0.0142 0.0425
Entamoeba histolytica glutamate synthase beta subunit, putative 0.005 0.0072 0.0231
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.2142 0.3628
Brugia malayi hypothetical protein 0.0479 0.1418 0.1418
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.005 0.0072 0.0157
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0079 0.0163 0.0181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Echinococcus multilocularis calpain 0.071 0.2142 0.2373
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0115 0.0276 0.0305
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0017 0.0018
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0782 0.2367 0.2619
Loa Loa (eye worm) hypothetical protein 0.0112 0.0267 0.0267
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.004 0.0044
Trypanosoma cruzi trypanothione reductase, putative 0.0188 0.0505 0.0556
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Brugia malayi exodeoxyribonuclease III family protein 0.0079 0.0163 0.0163
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0079 0.0163 0.0534
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Leishmania major NADH dehydrogenase, putative 0.005 0.0072 0.0117
Loa Loa (eye worm) hypothetical protein 0.0112 0.0267 0.0267
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0063 0.0113 0.0366
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.005 0.0072 0.0077
Brugia malayi mbt repeat family protein 0.005 0.0074 0.0074
Brugia malayi EGF-like domain containing protein 0.0064 0.0117 0.0117
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0188 0.0505 0.0851
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Schistosoma mansoni hypothetical protein 0.0064 0.0117 0.013
Brugia malayi proteasome subunit beta type 1 0.0072 0.0142 0.0142
Trichomonas vaginalis calpain, putative 0.0213 0.0585 0.1781
Echinococcus multilocularis gamma secretase subunit aph 1 0.0243 0.0676 0.0749
Entamoeba histolytica hypothetical protein, conserved 0.0107 0.0251 0.0829
Loa Loa (eye worm) hypothetical protein 0.0298 0.0849 0.0849
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0188 0.0505 0.0505
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0311 0.1301
Schistosoma mansoni calpain-7 (C02 family) 0.072 0.2172 0.2407
Schistosoma mansoni chromatin regulatory protein sir2 0.0034 0.0022 0.0025
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.005 0.0072 0.0211
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0775 0.2346 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.2142 0.237
Loa Loa (eye worm) animal heme peroxidase 0.0671 0.2019 0.2019
Onchocerca volvulus Glycogen phosphorylase homolog 0.0109 0.0259 0.0439
Plasmodium vivax hypothetical protein, conserved 0.0224 0.0619 0.2058
Echinococcus granulosus protein jagged 2 0.0064 0.0117 0.013
Trypanosoma brucei protein kinase, putative 0.0052 0.0079 0.0129
Trypanosoma cruzi cysteine peptidase, putative 0.0546 0.1627 0.18
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0074 0.0082
Giardia lamblia GTOR 0.0053 0.0082 0.0241
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.2142 0.237
Brugia malayi MH1 domain containing protein 0.0033 0.002 0.002
Leishmania major calmodulin, putative 0.0106 0.0247 0.0413
Brugia malayi Animal haem peroxidase family protein 0.0671 0.2019 0.2019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0146 0.0373 0.0413
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0213 0.0585 0.0645
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0306 0.0339
Brugia malayi Trypsin family protein 0.0115 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.034 0.0982 0.0982
Brugia malayi aspartic protease BmAsp-1, identical 0.0056 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0222 0.0613 0.0613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0048 0.0137
Treponema pallidum NADH oxidase 0.0188 0.0505 1
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.0259 0.0782
Brugia malayi beta-lactamase family protein 0.0112 0.0267 0.0267
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0138 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Trypanosoma cruzi oligopeptidase b 0.0775 0.2346 0.2596
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.004 0.004
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0091 0.0097
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0074 0.0082
Loa Loa (eye worm) hypothetical protein 0.0061 0.0108 0.0108
Schistosoma mansoni axis inhibition protein axin 0.004 0.004 0.0044
Echinococcus granulosus histone lysine methyltransferase setb 0.0124 0.0306 0.0339
Loa Loa (eye worm) hypothetical protein 0.0982 0.2995 0.2995
Giardia lamblia Cathepsin B precursor 0.0248 0.0694 0.2115
Leishmania major cysteine peptidase A (CPA) 0.0982 0.2995 0.5075
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0079 0.0233
Plasmodium vivax proteasome subunit beta type-1, putative 0.0072 0.0142 0.0464
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0188 0.0505 0.1677
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Brugia malayi EGF-like domain containing protein 0.0064 0.0117 0.0117
Schistosoma mansoni ran 0.0063 0.0113 0.0125
Echinococcus granulosus intermediate filament protein 0.0227 0.0626 0.0694
Loa Loa (eye worm) hypothetical protein 0.0127 0.0313 0.0313
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.107 0.3271 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0063 0.0113 0.0186
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0306 0.0339
Loa Loa (eye worm) hypothetical protein 0.0106 0.0247 0.0247
Trichomonas vaginalis centrin, putative 0.0106 0.0247 0.0745
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0121 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Entamoeba histolytica prolyl oligopeptidase family protein 0.0224 0.0619 0.2058
Plasmodium falciparum serine repeat antigen 3 0.0248 0.0694 0.231
Schistosoma mansoni calmodulin related calcium binding protein 0.0106 0.0247 0.0273
Brugia malayi Pre-SET motif family protein 0.0124 0.0306 0.0306
Echinococcus granulosus tumor protein p63 0.1779 0.5491 0.6083
Brugia malayi calpain 5 0.0497 0.1473 0.1473
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0267 0.0292
Onchocerca volvulus 0.0112 0.0267 0.0452
Brugia malayi MAP kinase sur-1 0.0052 0.0079 0.0079
Onchocerca volvulus 0.0982 0.2995 0.5078
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0248 0.0694 0.2115
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0188 0.0505 0.2132
Plasmodium vivax calpain, putative 0.071 0.2142 0.7149
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0248 0.0694 0.2115
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0072 0.0142 0.0157
Plasmodium vivax plasmepsin IV, putative 0.0056 0.0091 0.0293
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0047 0.0062 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Loa Loa (eye worm) hypothetical protein 0.2906 0.9027 0.9027
Loa Loa (eye worm) hypothetical protein 0.007 0.0135 0.0135
Brugia malayi MH2 domain containing protein 0.006 0.0104 0.0104
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.0288 0.0319
Brugia malayi cathepsin Z-like cysteine proteinase 0.0248 0.0694 0.0694
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1237 0.3793 0.8975
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0048 0.0076
Echinococcus multilocularis prolyl endopeptidase 0.1909 0.5899 0.6535
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0247 0.0745
Loa Loa (eye worm) cysteine protease 0.0982 0.2995 0.2995
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0112
Entamoeba histolytica hypothetical protein 0.0037 0.0032 0.0097
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0079 0.0088
Echinococcus multilocularis regulator of G protein signaling 0.004 0.004 0.0044
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.005 0.0072 0.0072
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0017 0.0018
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0188 0.0505 0.0556
Mycobacterium ulcerans NADH dehydrogenase 0.005 0.0072 0.0282
Trypanosoma brucei metacaspase 0.0172 0.0456 0.0768
Loa Loa (eye worm) ctsf protein 0.0982 0.2995 0.2995
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.005 0.0072 0.0117
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Brugia malayi fibroinase precursor 0.0248 0.0694 0.0694
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0072 0.0077
Trypanosoma cruzi conserved protein 0.0213 0.0585 0.0645
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Echinococcus multilocularis fat cadherin tumor suppressor 0.0064 0.0117 0.013
Brugia malayi MH2 domain containing protein 0.0879 0.2673 0.2673
Loa Loa (eye worm) prolyl oligopeptidase 0.0224 0.0619 0.0619
Echinococcus granulosus protein jagged 1 0.0064 0.0117 0.013
Echinococcus granulosus EF hand domain containing family member A2 0.0106 0.0247 0.0273
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0556
Schistosoma mansoni hypothetical protein 0.0179 0.0476 0.0528
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.004 0.0044
Toxoplasma gondii calcium-dependent protein kinase 0.0107 0.0253 0.0423
Loa Loa (eye worm) hypothetical protein 0.0112 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.1883 0.5817 0.5817
Loa Loa (eye worm) hypothetical protein 0.1172 0.3591 0.3591
Mycobacterium tuberculosis Conserved protein 0.0112 0.0267 0.0502
Leishmania major hypothetical protein, conserved 0.0213 0.0585 0.0987
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Schistosoma mansoni cathepsin F (C01 family) 0.0982 0.2995 0.3318
Giardia lamblia Cathepsin L-like protease 0.0248 0.0694 0.2115
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.004 0.0044
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Schistosoma mansoni calpain (C02 family) 0.071 0.2142 0.2373
Echinococcus multilocularis cathepsin b 0.2906 0.9027 1
Brugia malayi Smad1 0.006 0.0104 0.0104
Mycobacterium ulcerans NAD-dependent deacetylase 0.0034 0.0022 0.0068
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0079 0.0129
Toxoplasma gondii ABC1 family protein 0.0112 0.0267 0.0447
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.004 0.004
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0017 0.0017
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0585 0.1781
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0074 0.0074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0556
Toxoplasma gondii cathepsin CPC1 0.0248 0.0694 0.1172
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0456 0.1385
Schistosoma mansoni glycogen phosphorylase 0.0109 0.0259 0.0287
Trypanosoma brucei calpain-like protein, putative 0.071 0.2142 0.3628
Schistosoma mansoni DNA polymerase eta 0.0061 0.0108 0.012
Leishmania major cathepsin L-like protease 0.0982 0.2995 0.5075
Trypanosoma brucei metacaspase MCA2 0.0172 0.0456 0.0768
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Trichomonas vaginalis importin beta-1, putative 0.0069 0.0133 0.0396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1988 0.6148 0.6811
Loa Loa (eye worm) hypothetical protein 0.0085 0.0183 0.0183
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0108 0.0108
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0188 0.0505 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.0267 0.0295
Trypanosoma cruzi I/6 autoantigen, putative 0.0106 0.0247 0.027
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0172 0.0456 0.0768
Onchocerca volvulus 0.0064 0.0117 0.0199
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0061 0.0108 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.005 0.0072 0.008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0556
Brugia malayi Pre-SET motif family protein 0.0859 0.2609 0.2609
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.0163 0.0534
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0108 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.0694 0.2115
Schistosoma mansoni ets-related 0.0443 0.1306 0.1447
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.005 0.0072 0.0117
Giardia lamblia Cathepsin B precursor 0.0248 0.0694 0.2115
Echinococcus multilocularis neuronal calcium sensor 0.0106 0.0247 0.0273
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0074 0.0082
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0775 0.2346 0.4508
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0064 0.0204
Echinococcus granulosus neuronal calcium sensor 0.0106 0.0247 0.0273
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0047 0.0063 0.007
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0064 0.0112
Echinococcus granulosus expressed protein 0.077 0.233 0.2581
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Loa Loa (eye worm) hypothetical protein 0.0105 0.0246 0.0246
Entamoeba histolytica grainin, putative 0.0107 0.0251 0.0829
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0041 0.0041
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0056 0.0091 0.0149
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.0267 0.0502
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0034 0.0022 0.0021
Brugia malayi Intermediate filament tail domain containing protein 0.0227 0.0626 0.0626
Plasmodium falciparum cysteine proteinase falcipain 1 0.0546 0.1627 0.5428
Loa Loa (eye worm) hypothetical protein 0.007 0.0135 0.0135
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Echinococcus granulosus flap endonuclease 1 0.0028 0.0003 0.0004
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0106 0.0247 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0072 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0041 0.0046
Brugia malayi PXA domain containing protein 0.004 0.004 0.004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0108 0.0116
Schistosoma mansoni hypothetical protein 0.0064 0.0117 0.013
Onchocerca volvulus 0.0059 0.0102 0.0172
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1237 0.3793 0.7297
Brugia malayi glutathione reductase 0.0542 0.1616 0.1616
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0079 0.0129
Echinococcus granulosus delta-like protein 1 0.0064 0.0117 0.013
Plasmodium falciparum plasmepsin II 0.0056 0.0091 0.0293
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1375 0.4226 0.8131
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0072 0.0117
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0546 0.1627 0.1803
Echinococcus granulosus calumenin 0.0107 0.0251 0.0278
Echinococcus multilocularis chromatin regulatory protein sir2 0.0132 0.0329 0.0364
Schistosoma mansoni glutamate synthase 0.005 0.0072 0.008
Echinococcus multilocularis neurogenic locus notch protein 0.0064 0.0117 0.013
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.0267 0.0295
Trypanosoma cruzi cysteine peptidase, putative 0.0298 0.0849 0.0937
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.005 0.0072 0.0211
Leishmania major metacaspase, putative 0.0172 0.0456 0.0768
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Brugia malayi NAD-dependent deacetylase SIRT1 0.0146 0.0373 0.0373
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0248 0.0694 0.0694
Brugia malayi EGF-like domain containing protein 0.0064 0.0117 0.0117
Leishmania major programmed cell death 6 protein-like protein 0.0106 0.0247 0.0413
Onchocerca volvulus 0.0115 0.0276 0.0467
Loa Loa (eye worm) hypothetical protein 0.0112 0.0267 0.0267
Entamoeba histolytica hypothetical protein, conserved 0.0224 0.0619 0.2058
Giardia lamblia Hypothetical protein 0.0107 0.0251 0.0759
Entamoeba histolytica cysteine protease, putative 0.0248 0.0694 0.231
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0161 0.042 0.098
Loa Loa (eye worm) glycogen phosphorylase 0.0109 0.0259 0.0259
Loa Loa (eye worm) MH1 domain-containing protein 0.006 0.0104 0.0104
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0106 0.0247 0.0273
Onchocerca volvulus 0.0115 0.0276 0.0467
Schistosoma mansoni sulfide quinone reductase 0.005 0.0072 0.008
Schistosoma mansoni hypothetical protein 0.0106 0.0247 0.0273
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0982 0.2995 1
Trichomonas vaginalis calpain, putative 0.0213 0.0585 0.1781
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.005 0.0072 0.008
Schistosoma mansoni neuronal calcium sensor 0.0106 0.0247 0.0273
Giardia lamblia Cysteine protease 0.0248 0.0694 0.2115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.005 0.0072 0.0282
Echinococcus granulosus Dipeptidyl peptidase 9 0.0311 0.0892 0.0988
Schistosoma mansoni microtubule-associated protein tau 0.1424 0.4378 0.4851
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Echinococcus multilocularis snurportin 1 0.0911 0.277 0.3069
Loa Loa (eye worm) hypothetical protein 0.0146 0.0373 0.0373
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0183 0.0305
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0034 0.0022 0.0032
Echinococcus granulosus Glycosyl transferase family 35 0.0109 0.0259 0.0287
Plasmodium falciparum plasmepsin IX 0.0321 0.0923 0.3075
Echinococcus granulosus glutamate synthase 0.005 0.0072 0.008
Trichomonas vaginalis calcium binding protein, putative 0.0106 0.0247 0.0745
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0072 0.0142 0.0157
Echinococcus granulosus smad 0.006 0.0104 0.0115
Schistosoma mansoni intermediate filament proteins 0.0227 0.0626 0.0694
Echinococcus multilocularis caspase 3 0.0148 0.0381 0.0422
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0311 0.0892 0.0988
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0112
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0846 0.2568 0.2845
Entamoeba histolytica grainin 2 0.0106 0.0247 0.0814
Schistosoma mansoni calmodulin 0.0106 0.0247 0.0273
Echinococcus multilocularis TGF beta signal transducer SmadC 0.006 0.0104 0.0115
Loa Loa (eye worm) hypothetical protein 0.0105 0.0246 0.0246
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0213 0.0585 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0048 0.0137
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0047 0.0063 0.0101
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.004 0.004
Leishmania major cathepsin L-like protease 0.0982 0.2995 0.5075
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0107 0.0251 0.0278
Trichomonas vaginalis esterase, putative 0.0112 0.0267 0.0806
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0014 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Plasmodium vivax aspartyl protease, putative 0.0056 0.0091 0.0293
Loa Loa (eye worm) transcription factor SMAD2 0.0879 0.2673 0.2673
Leishmania major calpain protease-like protein 0.0213 0.0585 0.0987
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.004 0.0112
Trichomonas vaginalis calcium binding protein, putative 0.0106 0.0247 0.0745
Loa Loa (eye worm) hypothetical protein 0.0115 0.0276 0.0276
Onchocerca volvulus 0.0115 0.0276 0.0467
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.005 0.0072 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Schistosoma mansoni smad1 5 8 and 0.006 0.0104 0.0115
Schistosoma mansoni caspase-7 (C14 family) 0.0321 0.0921 0.1021
Schistosoma mansoni cytochrome P450 0.0029 0.0006 0.0007
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0248 0.0694 0.0694
Brugia malayi cathepsin Z-like cysteine proteinase 0.0248 0.0694 0.0694
Leishmania major centrin, putative 0.0106 0.0247 0.0413
Loa Loa (eye worm) hypothetical protein 0.0248 0.0694 0.0694
Leishmania major cathepsin L-like protease 0.1079 0.3299 0.5591
Trypanosoma brucei calmodulin, putative 0.0107 0.0251 0.0421
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0172 0.0456 0.0768
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0047 0.0063 0.0199
Echinococcus multilocularis dna polymerase eta 0.0061 0.0108 0.012
Loa Loa (eye worm) hypothetical protein 0.0227 0.0626 0.0626
Echinococcus multilocularis cathepsin L 0.0546 0.1627 0.1803
Giardia lamblia Cathepsin B precursor 0.107 0.3271 1
Schistosoma mansoni hypothetical protein 0.0037 0.0032 0.0036
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0585 0.1781
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0108 0.0178
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.1206 0.1336
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0022 0.0058
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0079 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0248 0.0694 0.2115
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Echinococcus granulosus calcium uptake protein 1 0.0107 0.0251 0.0278
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0347 0.0385
Plasmodium falciparum metacaspase 1 0.0172 0.0456 0.1513
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0061 0.0108 0.0108
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0072 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Trypanosoma brucei caltractin, putative 0.0106 0.0247 0.0413
Echinococcus granulosus axis inhibition protein axin 0.004 0.004 0.0044
Echinococcus granulosus EF HAND 1 calcium binding site 0.0106 0.0247 0.0273
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0311 0.0892 0.0985
Leishmania major cathepsin L-like protease 0.0982 0.2995 0.5075
Onchocerca volvulus Prolyl endopeptidase homolog 0.1909 0.5899 1
Giardia lamblia Thioredoxin reductase 0.005 0.0072 0.0211
Loa Loa (eye worm) hypothetical protein 0.0112 0.0267 0.0267
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0061 0.0108 0.012
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.005 0.0072 0.0157
Leishmania major proteasome beta 5 subunit, putative 0.0161 0.042 0.0706
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.0163 0.0534
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0213 0.0585 0.0645
Treponema pallidum exodeoxyribonuclease (exoA) 0.0079 0.0163 0.2097
Brugia malayi beta-lactamase 0.0112 0.0267 0.0267
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0227 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0115 0.0276 0.0276
Loa Loa (eye worm) fli-1 protein 0.0443 0.1306 0.1306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Leishmania major kinesin, putative 0.0497 0.1473 0.2493
Echinococcus multilocularis tar DNA binding protein 0.0124 0.0306 0.0339
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0222 0.0222
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0859 0.2609 0.2609
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0234 0.0234
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0079 0.0163 0.0163
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0047 0.0063 0.007
Leishmania major cytochrome p450-like protein 0.0029 0.0006 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2906 0.9027 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0248 0.0694 0.0769
Trypanosoma brucei unspecified product 0.0061 0.0108 0.0178
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0188 0.0505 0.0851
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0109 0.0259 0.0287
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0248 0.0694 0.0694
Brugia malayi calpain 5 0.0213 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Leishmania major sir2-family protein-like protein 0.0034 0.0022 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0248 0.0694 0.2115
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0132 0.0329 0.0364
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.005 0.0072 0.0072
Schistosoma mansoni peroxidasin 0.0671 0.2019 0.2236
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0072 0.0142 0.0425
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0022 0.0058
Brugia malayi cathepsin L precursor 0.0248 0.0694 0.0694
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.0259 0.0782
Schistosoma mansoni chromatin regulatory protein sir2 0.0034 0.0022 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0048 0.0137
Brugia malayi Cathepsin L-like precursor 0.0298 0.0849 0.0849
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0041 0.0041
Brugia malayi prolyl oligopeptidase family protein 0.0224 0.0619 0.0619
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0006 0.0003
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0003 0.0003
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.004 0.0044
Schistosoma mansoni regulator of G protein signaling 0.004 0.004 0.0044
Schistosoma mansoni chromatin regulatory protein sir2 0.0034 0.0022 0.0025
Trypanosoma brucei calpain, putative 0.0213 0.0585 0.0987
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0022 0.0058
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0715 0.2156 0.4142
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0063 0.0113 0.0113
Trypanosoma cruzi oligopeptidase b 0.0775 0.2346 0.2596
Schistosoma mansoni cathepsin F (C01 family) 0.0685 0.2062 0.2285
Giardia lamblia Hypothetical protein 0.0132 0.0329 0.0996
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0585 0.1781
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0053 0.0082 0.0134
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0146 0.0373 0.113
Trichomonas vaginalis mercuric reductase, putative 0.0188 0.0505 0.1535
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0034 0.0022 0.0063
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Loa Loa (eye worm) fibroinase 0.0982 0.2995 0.2995
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Loa Loa (eye worm) hypothetical protein 0.0092 0.0205 0.0205
Echinococcus granulosus transmembrane protease serine 3 0.0115 0.0276 0.0305
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0161 0.042 0.1274
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0685 0.2062 0.6301
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0248 0.0694 0.2115
Leishmania major calmodulin-like protein 0.0106 0.0247 0.0413
Entamoeba histolytica calcium binding family protein 0.0106 0.0247 0.0814
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0072 0.0211
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.005 0.0072 0.0117
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Brugia malayi prolyl oligopeptidase family protein 0.1909 0.5899 0.5899
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0306 0.0339
Loa Loa (eye worm) transcriptional regulator 0.0034 0.0022 0.0022
Onchocerca volvulus 0.026 0.0732 0.1241
Echinococcus granulosus cathepsin L 0.0546 0.1627 0.1803
Schistosoma mansoni terminal deoxycytidyl transferase 0.0061 0.0108 0.012
Giardia lamblia Cathepsin B precursor 0.0248 0.0694 0.2115
Echinococcus granulosus caspase 2 0.034 0.0982 0.1088
Brugia malayi transcriptional regulator, Sir2 family protein 0.0132 0.0329 0.0329
Brugia malayi Cathepsin L-like precursor 0.0982 0.2995 0.2995
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2906 0.9027 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0074 0.0125
Trypanosoma cruzi metacaspase, putative 0.0172 0.0456 0.0502
Plasmodium vivax vivapain-2 0.0982 0.2995 1
Trypanosoma cruzi calmodulin, putative 0.0106 0.0247 0.027
Toxoplasma gondii exonuclease III APE 0.0079 0.0163 0.0271
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0106 0.0248 0.0271
Onchocerca volvulus 0.005 0.0074 0.0125
Giardia lamblia Cathepsin L precursor 0.0248 0.0694 0.2115
Echinococcus multilocularis calpain family protein 1, d 0.1386 0.426 0.472
Echinococcus multilocularis 0.0029 0.0006 0.0007
Schistosoma mansoni chromatin regulatory protein sir2 0.0132 0.0329 0.0364
Loa Loa (eye worm) hypothetical protein 0.0685 0.2062 0.2062
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0146 0.0373 0.113
Trichomonas vaginalis hypothetical protein 0.0213 0.0585 0.1781
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0106 0.0247 0.0745
Echinococcus granulosus slit 2 protein 0.0064 0.0117 0.013
Schistosoma mansoni hypothetical protein 0.0029 0.0006 0.0007
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0064 0.0204
Schistosoma mansoni hypothetical protein 0.0064 0.0117 0.013
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.005 0.0072 0.0231
Plasmodium vivax vivapain-3 0.0546 0.1627 0.5428
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0546 0.1627 0.1803
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0115 0.0276 0.0305
Echinococcus multilocularis lamin dm0 0.0227 0.0626 0.0694
Loa Loa (eye worm) blistered cuticle protein 3 0.0671 0.2019 0.2019
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Entamoeba histolytica prolyl oligopeptidase family protein 0.0224 0.0619 0.2058
Echinococcus granulosus acylamino acid releasing enzyme 0.0224 0.0619 0.0686
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0053 0.0082 0.0134
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0213 0.0585 0.0645
Schistosoma mansoni TGF-beta signal transducer Smad2 0.006 0.0104 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0306 0.0339
Leishmania major hypothetical protein, conserved 0.005 0.0072 0.0117
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0138 0.0349 0.0349
Schistosoma mansoni cellular tumor antigen P53 0.026 0.0732 0.0811
Entamoeba histolytica calmodulin, putative 0.0106 0.0247 0.0814
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0775 0.2346 0.2596
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0248 0.0694 0.231
Echinococcus granulosus GPCR family 2 0.0032 0.0017 0.0018
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.005 0.0072 0.0127
Toxoplasma gondii preprocathepsin c precursor, putative 0.0248 0.0694 0.1172
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0306 0.0339
Loa Loa (eye worm) hypothetical protein 0.0115 0.0276 0.0276
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0248 0.0694 0.2115
Leishmania major calmodulin-like protein 0.0106 0.0247 0.0413
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0079 0.0163 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0007
Schistosoma mansoni hypothetical protein 0.0032 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0046 0.0059 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0096 0.0106
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0109 0.0259 0.0287
Loa Loa (eye worm) animal heme peroxidase 0.0671 0.2019 0.2019
Toxoplasma gondii aspartyl protease ASP1 0.0056 0.0091 0.0149
Entamoeba histolytica protein kinase, putative 0.0497 0.1474 0.4917
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0161 0.042 0.0465
Brugia malayi cathepsin F-like cysteine proteinase 0.0248 0.0694 0.0694
Onchocerca volvulus 0.0156 0.0405 0.0686
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0172 0.0456 0.0456
Loa Loa (eye worm) beta-lactamase 0.0112 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0248 0.0694 0.0694
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0064 0.0117 0.0199
Schistosoma mansoni cercarial elastase (S01 family) 0.0115 0.0276 0.0305
Toxoplasma gondii cathepsin B 0.107 0.3271 0.5544
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0188 0.0505 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0542 0.1616 0.3101
Onchocerca volvulus 0.0112 0.0267 0.0452
Entamoeba histolytica thioredoxin reductase, putative 0.005 0.0072 0.0231
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1988 0.6148 0.6811
Brugia malayi Papain family cysteine protease containing protein 0.0248 0.0694 0.0694
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0006 0.0003
Echinococcus granulosus gamma secretase subunit aph 1 0.0243 0.0676 0.0749
Brugia malayi intermediate filament protein 0.0227 0.0626 0.0626
Toxoplasma gondii centrin, putative 0.0106 0.0247 0.0413
Echinococcus multilocularis cysteine protease 0.0982 0.2995 0.3318
Loa Loa (eye worm) programmed cell death 8 0.005 0.0072 0.0072
Echinococcus granulosus calpain 5 0.071 0.2142 0.2373
Trichomonas vaginalis glutamate synthase, putative 0.005 0.0072 0.0211
Entamoeba histolytica hypothetical protein, conserved 0.0034 0.0022 0.0063
Leishmania major phospholipase c-like protein 0.0106 0.0247 0.0413
Brugia malayi RNA binding protein 0.0124 0.0306 0.0306
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1883 0.5817 0.6445
Echinococcus multilocularis calbindin 32 0.0107 0.0251 0.0278
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0108 0.0116
Leishmania major calcineurin B subunit, putative 0.0106 0.0247 0.0413
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0224 0.0619 0.2058
Loa Loa (eye worm) hypothetical protein 0.0172 0.0456 0.0456
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Echinococcus granulosus neurogenic locus notch protein 0.0064 0.0117 0.013
Mycobacterium ulcerans lipase LipD 0.0112 0.0267 0.1113
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Trypanosoma brucei metacaspase MCA3 0.0172 0.0456 0.0768
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0321 0.0921 0.1021
Toxoplasma gondii troponin c, isotype gamma, putative 0.0106 0.0247 0.0413
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.005 0.0072 0.0127
Plasmodium vivax unspecified product 0.0546 0.1627 0.5428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0007
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0079 0.0084
Brugia malayi Cathepsin L-like precursor 0.0685 0.2062 0.2062
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0161 0.042 0.0797
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0112
Loa Loa (eye worm) hypothetical protein 0.0112 0.0267 0.0267
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0133 0.0396
Brugia malayi RNA, U transporter 1 0.0243 0.0676 0.0676
Loa Loa (eye worm) sirtuin 4 0.0034 0.0022 0.0022
Giardia lamblia Hypothetical protein 0.0248 0.0694 0.2115
Schistosoma mansoni disulfide oxidoreductase 0.005 0.0072 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0546 0.1627 0.4969
Echinococcus granulosus EF hand domain containing family member A2 0.0107 0.0251 0.0278
Onchocerca volvulus 0.0248 0.0694 0.1177
Plasmodium falciparum plasmepsin VIII, putative 0.0056 0.0091 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Loa Loa (eye worm) hypothetical protein 0.0224 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Trypanosoma cruzi cruzipain precursor, putative 0.0298 0.0849 0.0937
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0324 0.0359
Brugia malayi Calcium binding EGF domain containing protein 0.0064 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Echinococcus granulosus cathepsin L 0.0248 0.0694 0.0769
Loa Loa (eye worm) RNA binding protein 0.0124 0.0306 0.0306
Onchocerca volvulus 0.0064 0.0117 0.0199
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0347 0.0385
Trypanosoma brucei Calpain-like protein CALP1.3 0.0213 0.0585 0.0987
Giardia lamblia Transcriptional regulator, Sir2 family 0.0034 0.0022 0.0058
Onchocerca volvulus 0.0978 0.2981 0.5054
Loa Loa (eye worm) hypothetical protein 0.0248 0.0694 0.0694
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0061 0.0108 0.012
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0053 0.0082 0.0087
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0311 0.0892 0.0988
Trypanosoma brucei oligopeptidase b 0.0775 0.2346 0.3974
Trichomonas vaginalis calmodulin-2, putative 0.0106 0.0247 0.0745
Brugia malayi Peroxidasin 0.0671 0.2019 0.2019
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.013 0.013
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.004 0.0062
Plasmodium falciparum serine repeat antigen 7 0.0248 0.0694 0.231
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0982 0.2995 0.3318
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0063 0.0113 0.0121
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0053 0.0082 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.004 0.0111
Toxoplasma gondii HEAT repeat-containing protein 0.0085 0.0183 0.0305
Echinococcus granulosus survival motor neuron protein 1 0.0479 0.1418 0.1571
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0115 0.0276 0.0276
Trypanosoma cruzi I/6 autoantigen, putative 0.0106 0.0247 0.027
Onchocerca volvulus 0.0671 0.2019 0.3423
Plasmodium falciparum plasmepsin X 0.0321 0.0923 0.3075
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Onchocerca volvulus 0.0112 0.0267 0.0452
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.005 0.0072 0.0072
Trypanosoma cruzi metacaspase 5, putative 0.0172 0.0456 0.0502
Loa Loa (eye worm) hypothetical protein 0.0115 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0082 0.0241
Loa Loa (eye worm) hypothetical protein 0.0092 0.0205 0.0205
Loa Loa (eye worm) thioredoxin reductase 0.0542 0.1616 0.1616
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0372 0.1081 0.1198
Leishmania major proteasome beta 2 subunit, putative 0.0047 0.0063 0.0101
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0188 0.0505 0.1677
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0048 0.0076
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0108 0.0116
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0096 0.0106
Leishmania major centrin, putative,caltractin, putative 0.0106 0.0247 0.0413
Trypanosoma cruzi calpain cysteine peptidase, putative 0.071 0.2142 0.237
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0585 0.1781
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0107 0.0251 0.0275
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0079 0.0079
Mycobacterium leprae Probable lipase LipE 0.0112 0.0267 0.0617
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0007
Plasmodium falciparum plasmepsin VI 0.0056 0.0091 0.0293
Brugia malayi Cathepsin L-like precursor 0.0982 0.2995 0.2995
Brugia malayi PXA domain containing protein 0.004 0.004 0.004
Echinococcus multilocularis cathepsin L cysteine protease 0.0982 0.2995 0.3318
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.005 0.0072 0.0231
Trypanosoma cruzi metacaspase, putative 0.0172 0.0456 0.0502
Giardia lamblia Alanyl dipeptidyl peptidase 0.0224 0.0619 0.1884
Entamoeba histolytica hypothetical protein 0.0037 0.0032 0.0097
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0161 0.042 0.1274
Onchocerca volvulus Cathepsin F homolog 0.0982 0.2995 0.5078
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.107 0.3271 0.3624
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0212 0.0232
Echinococcus granulosus proteasome prosome macropain 0.0161 0.042 0.0465
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1909 0.5899 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0172 0.0456 0.1385
Plasmodium vivax vivapain-2 0.0982 0.2995 1
Echinococcus multilocularis enteropeptidase 0.0115 0.0276 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.0694 0.2115
Echinococcus multilocularis lamin 0.0227 0.0626 0.0694
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Schistosoma mansoni cathepsin D (A01 family) 0.0366 0.1062 0.1177
Entamoeba histolytica hypothetical protein 0.004 0.004 0.0123
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0017 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Echinococcus granulosus fibropellin Ia 0.0064 0.0117 0.013
Plasmodium falciparum serine repeat antigen 2 0.0248 0.0694 0.231
Echinococcus granulosus notch 0.0064 0.0117 0.013
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0079 0.0163 0.067
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0248 0.0694 0.231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0015 0.0037
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0188 0.0505 0.2132
Schistosoma mansoni ap endonuclease 0.0079 0.0163 0.0181
Echinococcus granulosus neurogenic locus notch protein 0.0064 0.0117 0.013
Onchocerca volvulus Putative cubilin 0.0064 0.0117 0.0199
Trypanosoma cruzi cysteine proteinase, putative 0.0546 0.1627 0.18
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0146 0.0373 0.113
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0079 0.0233
Brugia malayi Trypsin family protein 0.0115 0.0276 0.0276
Echinococcus multilocularis slit 2 protein 0.0064 0.0117 0.013
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0188 0.0505 1
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0062 0.0069
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0224 0.0619 0.0686
Onchocerca volvulus Peroxidasin homolog 0.0671 0.2019 0.3423
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0092 0.0205 0.0205
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.0163 0.0489
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0132 0.0329 0.0361
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0017 0.0017
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0248 0.0694 0.231
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0161 0.042 0.042
Toxoplasma gondii NADPH-glutathione reductase 0.0188 0.0505 0.0851
Plasmodium falciparum cysteine proteinase falcipain 3 0.0982 0.2995 1
Schistosoma mansoni survival motor neuron protein 0.0098 0.0222 0.0246
Loa Loa (eye worm) calmodulin-like protein 0.0106 0.0247 0.0247
Mycobacterium leprae conserved hypothetical protein 0.0112 0.0267 0.0617
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.0311 0.0522
Schistosoma mansoni caspase-3 (C14 family) 0.0321 0.0921 0.1021
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0056 0.0091 0.0091
Echinococcus granulosus apoptotic protease activating factor 1 0.0168 0.0442 0.049
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0072 0.0142 0.0464
Plasmodium falciparum serine repeat antigen 9 0.0248 0.0694 0.231
Schistosoma mansoni glutamate synthase 0.005 0.0072 0.008
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.0306 0.0306
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0982 0.2995 0.2995
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0041 0.0046
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0248 0.0694 0.231
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0041 0.0046
Trypanosoma brucei protein I/6 0.0106 0.0247 0.0413
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.0267 0.1113
Brugia malayi Cytochrome P450 family protein 0.0029 0.0006 0.0006
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0108 0.0435
Loa Loa (eye worm) hypothetical protein 0.0125 0.0307 0.0307
Loa Loa (eye worm) nuclear factor I 0.0033 0.002 0.002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Mycobacterium tuberculosis Probable reductase 0.1237 0.3793 0.7297
Trypanosoma brucei mitochondrial calcium uptake 1 0.0106 0.0247 0.0413
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0091 0.0091
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0115 0.0276 0.0276
Echinococcus multilocularis musashi 0.0227 0.0626 0.0694
Schistosoma mansoni regulator of G protein signaling 0.004 0.004 0.0044
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Brugia malayi Trypsin family protein 0.0115 0.0276 0.0276
Onchocerca volvulus 0.0982 0.2995 0.5078
Loa Loa (eye worm) hypothetical protein 0.0068 0.013 0.013
Echinococcus multilocularis importin subunit beta 1 0.0085 0.0183 0.0203
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.005 0.0072 0.0282
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0224 0.0619 0.2058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0982 0.2995 0.9155
Loa Loa (eye worm) hypothetical protein 0.0056 0.0091 0.0091
Echinococcus granulosus cytochrome P450 2K1 0.0029 0.0006 0.0007
Onchocerca volvulus Cathepsin L homolog 0.0982 0.2995 0.5078
Schistosoma mansoni reticulocalbin 0.0106 0.0247 0.0273
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0064 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0546 0.1627 0.2754
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.0267 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0456 0.1385
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Onchocerca volvulus Cathepsin L homolog 0.0982 0.2995 0.5078
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.005 0.0072 0.0117
Echinococcus granulosus caspase 8 0.0172 0.0456 0.0505
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0224 0.0619 0.1044
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.107 0.3271 0.3622
Loa Loa (eye worm) hypothetical protein 0.0112 0.0267 0.0267
Brugia malayi MH1 domain containing protein 0.006 0.0104 0.0104
Brugia malayi hypothetical protein 0.0115 0.0276 0.0276
Brugia malayi hypothetical protein 0.0168 0.0442 0.0442
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0034 0.0022 0.0025
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0034 0.0022 0.0031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0267 0.0806
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0056 0.0091 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0248 0.0694 0.2115
Brugia malayi Cathepsin L-like precursor 0.0685 0.2062 0.2062
Giardia lamblia Glycogen phosphorylase 0.0109 0.0259 0.0782
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0053 0.0082 0.0091
Loa Loa (eye worm) hypothetical protein 0.0298 0.0849 0.0849
Toxoplasma gondii thioredoxin reductase 0.0542 0.1616 0.2735
Brugia malayi Cell death protein 3 precursor 0.034 0.0982 0.0982
Entamoeba histolytica cysteine proteinase, putative 0.0546 0.1627 0.5428
Leishmania major hypothetical protein, conserved 0.0106 0.0247 0.0413
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0213 0.0585 0.0645
Loa Loa (eye worm) trypsin family protein 0.0115 0.0276 0.0276
Schistosoma mansoni notch 0.0064 0.0117 0.013
Trypanosoma brucei unspecified product 0.0042 0.0048 0.0076
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2906 0.9027 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0213 0.0585 0.0645
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Brugia malayi MH1 domain containing protein 0.006 0.0104 0.0104
Trypanosoma brucei calpain-like protein, putative 0.071 0.2142 0.3628
Trypanosoma brucei calmodulin, putative 0.0106 0.0247 0.0413
Leishmania major silent information regulator 2, putative 0.0132 0.0329 0.0552
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0306 0.0339
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0091 0.0148
Trichomonas vaginalis calmodulin, putative 0.0106 0.0247 0.0745
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Giardia lamblia NADH oxidase lateral transfer candidate 0.0188 0.0505 0.1535
Loa Loa (eye worm) hypothetical protein 0.0101 0.0234 0.0234
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.2142 0.237
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0306 0.0339
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0188 0.0505 0.0556
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Schistosoma mansoni hypothetical protein 0.0168 0.0442 0.049
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0536 0.1598 0.177
Echinococcus granulosus GTP binding nuclear protein Ran 0.0063 0.0113 0.0125
Echinococcus granulosus programmed cell death protein 0.0106 0.0247 0.0273
Brugia malayi Papain family cysteine protease containing protein 0.0982 0.2995 0.2995
Loa Loa (eye worm) hypothetical protein 0.0127 0.0313 0.0313
Schistosoma mansoni sulfide quinone reductase 0.005 0.0072 0.008
Schistosoma mansoni importin beta-1 0.0085 0.0183 0.0203
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0321 0.0921 0.1021
Echinococcus multilocularis programmed cell death protein 0.0106 0.0247 0.0273
Onchocerca volvulus 0.0056 0.0091 0.0154
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0079 0.0163 0.0177
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0982 0.2995 0.9155
Echinococcus multilocularis notch 0.0064 0.0117 0.013
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.2142 0.237
Brugia malayi carbohydrate phosphorylase 0.0109 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0068 0.013 0.013
Mycobacterium ulcerans hypothetical protein 0.0112 0.0267 0.1113
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.004 0.0044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0347 0.0385
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0248 0.0694 0.2115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0007
Plasmodium falciparum thioredoxin reductase 0.0542 0.1616 0.5389
Onchocerca volvulus 0.0115 0.0276 0.0467
Loa Loa (eye worm) hypothetical protein 0.0248 0.0694 0.0694
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0124 0.0306 0.0339
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1237 0.3793 0.7297
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.005 0.0072 0.0282
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0133 0.0133
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.004 0.0044
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0987
Plasmodium vivax metacaspase 1, putative 0.0172 0.0456 0.1513
Onchocerca volvulus 0.0671 0.2019 0.3423
Onchocerca volvulus 0.0064 0.0117 0.0199
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0056 0.0091 0.0101
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.071 0.2142 0.3628
Onchocerca volvulus 0.0168 0.0442 0.075
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.005 0.0072 0.0282
Schistosoma mansoni cpg binding protein 0.0063 0.0112 0.0124
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.004 0.0044
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0115 0.0276 0.0305
Entamoeba histolytica cysteine proteinase, putative 0.0685 0.2062 0.6882
Loa Loa (eye worm) hypothetical protein 0.0064 0.0117 0.0117
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0248 0.0694 0.0769
Trypanosoma brucei cysteine peptidase C (CPC) 0.107 0.3271 0.5544
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0108 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0982 0.2995 0.9155
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0775 0.2346 0.3974
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.0267 0.0267
Brugia malayi aspartic protease BmAsp-2, identical 0.0056 0.0091 0.0091
Echinococcus granulosus cathepsin L cysteine proteinase 0.0982 0.2995 0.3318
Schistosoma mansoni centrin-related 0.0106 0.0247 0.0273
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0072 0.0117
Onchocerca volvulus Neurogenic locus notch homolog 0.0064 0.0118 0.02
Brugia malayi Delta serrate ligand family protein 0.0064 0.0117 0.0117
Entamoeba histolytica cysteine proteinase 2 0.0546 0.1627 0.5428
Leishmania major calpain family cysteine protease-like protein 0.0213 0.0585 0.0987
Trypanosoma cruzi cysteine peptidase, putative 0.0982 0.2995 0.3316
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0248 0.0694 0.0769
Echinococcus multilocularis neurocalcin 0.0106 0.0247 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0024 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591
Leishmania major cytochrome p450-like protein 0.0029 0.0006 0.0005
Entamoeba histolytica calcium-binding protein, putative 0.0106 0.0247 0.0814
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0053 0.0082 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0456 0.1385
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0034 0.0022 0.0063
Entamoeba histolytica hypothetical protein 0.0069 0.0133 0.0433
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0061 0.0108 0.012
Leishmania major hypothetical protein, conserved 0.0112 0.0267 0.0447
Schistosoma mansoni laminin gamma-3 chain 0.0064 0.0117 0.013
Onchocerca volvulus 0.0046 0.0059 0.0101
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0214 0.0588 0.0651
Plasmodium falciparum plasmepsin VII 0.0056 0.0091 0.0293
Trichomonas vaginalis set domain proteins, putative 0.0978 0.2981 0.911
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0063 0.0113 0.0113
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0053 0.0082 0.0264
Echinococcus granulosus caspase 0.0321 0.0921 0.1021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0108 0.0116
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.005 0.0072 0.0072
Onchocerca volvulus 0.0227 0.0626 0.1062
Plasmodium vivax aspartyl proteinase, putative 0.0056 0.0091 0.0293
Plasmodium falciparum serine repeat antigen 6 0.0248 0.0694 0.231
Giardia lamblia Cathepsin B precursor 0.107 0.3271 1
Echinococcus multilocularis caspase 2 0.034 0.0982 0.1088
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.0311 0.0344
Giardia lamblia Glutamate synthase 0.005 0.0072 0.0211
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0102 0.0102
Echinococcus multilocularis neural cadherin 0.0064 0.0117 0.013
Brugia malayi Trypsin family protein 0.0115 0.0276 0.0276
Trypanosoma brucei Metacaspase-4 0.0172 0.0456 0.0768
Brugia malayi Ets-domain containing protein 0.0146 0.0374 0.0374
Schistosoma mansoni hypothetical protein 0.0115 0.0276 0.0305
Schistosoma mansoni hypothetical protein 0.0064 0.0117 0.013
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0096 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0248 0.0694 0.2115
Echinococcus multilocularis survival motor neuron protein 1 0.0479 0.1418 0.1571
Trypanosoma cruzi kinesin, putative 0.0497 0.1473 0.1629
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0213 0.0585 0.0987
Loa Loa (eye worm) hypothetical protein 0.0115 0.0276 0.0276
Brugia malayi Papain family cysteine protease containing protein 0.0546 0.1627 0.1627
Onchocerca volvulus Peroxidase homolog 0.0671 0.2019 0.3423
Onchocerca volvulus 0.0106 0.0247 0.0418
Loa Loa (eye worm) hypothetical protein 0.0033 0.002 0.002
Echinococcus granulosus cathepsin l1 0.0685 0.2062 0.2285
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0146 0.0373 0.113
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0213 0.0585 0.0645
Trypanosoma brucei hypothetical protein, conserved 0.0106 0.0247 0.0413
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1909 0.5899 0.6535
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0248 0.0694 0.231
Schistosoma mansoni chromatin regulatory protein sir2 0.0132 0.0329 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.004 0.0111
Brugia malayi hypothetical protein 0.004 0.004 0.004
Plasmodium vivax proteasome subunit beta type-5, putative 0.0161 0.042 0.1392
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0053 0.0082 0.0082
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.005 0.0072 0.0117
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1375 0.4226 0.8131
Loa Loa (eye worm) hypothetical protein 0.0069 0.0133 0.0133
Brugia malayi Calcium binding EGF domain containing protein 0.0064 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0032 0.0017 0.0018
Echinococcus granulosus neurogenic locus protein delta 0.0064 0.0117 0.013
Entamoeba histolytica cysteine protease, putative 0.0546 0.1627 0.5428
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0161 0.042 0.1392
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.0311 0.0587
Loa Loa (eye worm) calpain 0.071 0.2142 0.2142
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0132 0.0329 0.0552
Loa Loa (eye worm) hypothetical protein 0.0671 0.2019 0.2019
Brugia malayi cathepsin B-like cysteine proteinase 0.2906 0.9027 0.9027
Trypanosoma cruzi major cysteine proteinase, putative 0.0248 0.0694 0.0766
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1079 0.3299 0.5591

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.5 uM Inhibition of Sprague-Dawley rat spleen microsome HO1 ChEMBL. 17339115
IC50 (binding) = 4 uM Inhibition of Sprague-Dawley rat brain microsome HO2 ChEMBL. 17339115
IC50 (functional) = 70 uM Antimalarial activity against Plasmodium falciparum ChEMBL. 16495054
Inhibition (binding) = 90 % Inhibition of Sprague-Dawley rat brain microsome HO2 at 100 uM relative to control ChEMBL. 17339115

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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