Detailed information for compound 103478

Basic information

Technical information
  • TDR Targets ID: 103478
  • Name: (2S)-5-[3-(4-carbamimidoylphenyl)-1-methyl-2, 4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]-2-[ (3,5-dimethyl-1,2-oxazol-4-yl)sulfonylamino]- 5-oxopentanoic acid
  • MW: 589.621 | Formula: C25H31N7O8S
  • H donors: 3 H acceptors: 8 LogP: -0.49 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N1CCC2(CC1)C(=O)N(C(=O)N2C)c1ccc(cc1)C(=N)N)CC[C@@H](C(=O)O)NS(=O)(=O)c1c(C)noc1C
  • InChi: 1S/C25H31N7O8S/c1-14-20(15(2)40-28-14)41(38,39)29-18(22(34)35)8-9-19(33)31-12-10-25(11-13-31)23(36)32(24(37)30(25)3)17-6-4-16(5-7-17)21(26)27/h4-7,18,29H,8-13H2,1-3H3,(H3,26,27)(H,34,35)/t18-/m0/s1
  • InChiKey: ZQUWZIRXWNVFRR-SFHVURJKSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-5-[3-(4-carbamimidoylphenyl)-1-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]-2-[(3,5-dimethylisoxazol-4-yl)sulfonylamino]-5-oxo-pentanoic acid
  • (2S)-5-[3-(4-carbamimidoylphenyl)-1-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]-2-[(3,5-dimethyl-4-isoxazolyl)sulfonylamino]-5-oxopentanoic acid
  • (2S)-5-[3-(4-carbamimidoylphenyl)-1-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]-2-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonylamino]-5-oxo-pentanoic acid
  • (2S)-5-[3-(4-amidinophenyl)-2,4-diketo-1-methyl-1,3,8-triazaspiro[4.5]decan-8-yl]-2-[(3,5-dimethylisoxazol-4-yl)sulfonylamino]-5-keto-valeric acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma mansoni integrin alpha Get druggable targets OG5_129341 All targets in OG5_129341
Brugia malayi Integrin alpha pat-2 precursor Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06476 integrin alpha 2B, putative Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus multilocularis integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus granulosus integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum IPR013513,Integrin alpha chain, C-terminal cytoplasmic region,domain-containing Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) integrin alpha pat-2 Get druggable targets OG5_129341 All targets in OG5_129341
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi notch-like transmembrane receptor 0.0049 0.0178 0.0178
Giardia lamblia Hypothetical protein 0.0083 0.0466 0.1714
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.009 0.009
Toxoplasma gondii exonuclease III APE 0.0058 0.0256 0.0933
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.009 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1729
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Loa Loa (eye worm) trypsin family protein 0.0182 0.1291 0.1291
Echinococcus multilocularis cysteine protease 0.0344 0.2652 0.3507
Trypanosoma brucei mitochondrial calcium uptake 1 0.005 0.0183 0.0506
Loa Loa (eye worm) hypothetical protein 0.005 0.0183 0.0183
Onchocerca volvulus Peroxidasin homolog 0.0419 0.3281 0.7526
Brugia malayi Importin beta-1 subunit 0.0029 0.0009 0.0009
Trypanosoma cruzi cysteine proteinase, putative 0.0189 0.1352 0.1876
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.009 0.012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Echinococcus granulosus slit 2 protein 0.0049 0.0178 0.0236
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0128 0.0844 0.1117
Trypanosoma cruzi cysteine peptidase, putative 0.0438 0.3445 0.4855
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0331 0.2548 0.739
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0083 0.0466 0.1714
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0344 0.1268
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0326 0.2506 0.7245
Schistosoma mansoni chromatin regulatory protein sir2 0.0033 0.0044 0.0059
Brugia malayi transcriptional regulator, Sir2 family protein 0.0128 0.0844 0.0844
Brugia malayi Animal haem peroxidase family protein 0.0419 0.3281 0.3281
Toxoplasma gondii cathepsin CPL 0.0344 0.2652 1
Plasmodium falciparum plasmepsin VI 0.0111 0.0701 0.2618
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0371 0.0858
Schistosoma mansoni ets-related 0.0442 0.3474 0.4597
Brugia malayi A-kinase anchor protein 10, precursor 0.0039 0.009 0.009
Entamoeba histolytica cysteine protease, putative 0.0083 0.0466 0.1617
Trypanosoma cruzi conserved protein 0.01 0.0603 0.081
Entamoeba histolytica cysteine proteinase, putative 0.0238 0.1766 0.6602
Schistosoma mansoni importin beta-1 0.0029 0.0009 0.0012
Brugia malayi PXA domain containing protein 0.0039 0.009 0.009
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.3627 1
Schistosoma mansoni axis inhibition protein axin 0.0039 0.009 0.012
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.009 0.0119
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0189 0.1352 0.179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0466 0.1106
Loa Loa (eye worm) calpain 0.0331 0.2548 0.2548
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0371 0.1053
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0259 0.194 0.2568
Toxoplasma gondii aspartyl protease 0.0075 0.0399 0.1474
Echinococcus multilocularis calpain A 0.0929 0.7562 1
Brugia malayi Ets-domain containing protein 0.0146 0.0988 0.0988
Trypanosoma cruzi cysteine peptidase, putative 0.0438 0.3445 0.4855
Loa Loa (eye worm) hypothetical protein 0.0083 0.0466 0.0466
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.01 0.0603 0.081
Loa Loa (eye worm) hypothetical protein 0.0779 0.6304 0.6304
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0142 0.0959 0.24
Echinococcus granulosus EF hand domain containing family member A2 0.005 0.0189 0.025
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0083 0.0466 0.1106
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0344 0.0442
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.009 0.0121
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0766 0.0766
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1708
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0182 0.1291 0.1291
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0603 0.1466
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0287 0.038
Entamoeba histolytica protein kinase, putative 0.0232 0.1712 0.6396
Echinococcus granulosus fibropellin Ia 0.0049 0.0178 0.0236
Onchocerca volvulus 0.0238 0.1766 0.4051
Trypanosoma brucei cysteine peptidase C (CPC) 0.0326 0.2506 0.7265
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0155 0.1065 0.1065
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.066 0.1616
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.3281 0.3281
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0182 0.1291 0.1707
Brugia malayi beta-lactamase family protein 0.0072 0.0371 0.0371
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0034 0.0034
Onchocerca volvulus 0.0072 0.0371 0.0852
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0083 0.0466 0.0617
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0083 0.0466 0.1106
Entamoeba histolytica cysteine proteinase, putative 0.0189 0.1352 0.5016
Giardia lamblia Cathepsin L precursor 0.0083 0.0466 0.1714
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0256 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Loa Loa (eye worm) hypothetical protein 0.0106 0.0654 0.0654
Brugia malayi Peroxidasin 0.0419 0.3281 0.3281
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0083 0.0466 0.1617
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0344 0.0442
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.005 0.0183 0.0506
Giardia lamblia Cysteine protease 0.0083 0.0466 0.1714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Echinococcus granulosus calumenin 0.005 0.0189 0.025
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.066 0.1616
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0344 0.1268
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0033 0.0044 0.0132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Brugia malayi regulator of G-protein signaling rgs-7 0.0039 0.009 0.009
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0344 0.0975
Echinococcus multilocularis neurogenic locus protein delta 0.0049 0.0178 0.0236
Leishmania major oligopeptidase b 0.0103 0.0631 0.1751
Brugia malayi Papain family cysteine protease containing protein 0.0344 0.2652 0.2652
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Echinococcus multilocularis calumenin 0.005 0.0189 0.025
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0371 0.0491
Entamoeba histolytica cysteine proteinase, putative 0.0344 0.2652 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0142 0.0959 0.24
Echinococcus granulosus neurocalcin 0.005 0.0183 0.0243
Leishmania major phospholipase c-like protein 0.005 0.0183 0.0437
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0371 0.0491
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0603 0.081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0256 0.086
Schistosoma mansoni hypothetical protein 0.0049 0.0178 0.0236
Mycobacterium ulcerans Sir2-like regulatory protein 0.0033 0.0044 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0371 0.048
Loa Loa (eye worm) hypothetical protein 0.0182 0.1291 0.1291
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0083 0.0466 0.1714
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0045 0.0143 0.0188
Loa Loa (eye worm) hypothetical protein 0.0152 0.1041 0.1041
Schistosoma mansoni cathepsin F (C01 family) 0.0344 0.2652 0.351
Brugia malayi Cytochrome P450 family protein 0.0032 0.0034 0.0034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.2548 0.3578
Brugia malayi transcriptional regulator, Sir2 family protein 0.0033 0.0044 0.0044
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.009 0.009
Leishmania major centrin, putative 0.005 0.0183 0.0437
Leishmania major programmed cell death 6 protein-like protein 0.005 0.0183 0.0437
Brugia malayi aspartic protease BmAsp-1, identical 0.0075 0.0399 0.0399
Echinococcus multilocularis caspase 8 0.0123 0.0796 0.1053
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0263 0.0348
Schistosoma mansoni hypothetical protein 0.0049 0.0178 0.0236
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Toxoplasma gondii cathepsin CPC1 0.0083 0.0466 0.1728
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0083 0.0466 0.1728
Loa Loa (eye worm) beta-lactamase 0.0072 0.0371 0.0371
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.2548 0.3578
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.1352 0.3909
Giardia lamblia Cathepsin L precursor 0.0083 0.0466 0.1714
Brugia malayi EGF-like domain containing protein 0.0049 0.0178 0.0178
Echinococcus multilocularis peroxidasin 0.0419 0.3281 0.4338
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0371 0.0913
Echinococcus multilocularis neural cadherin 0.0049 0.0178 0.0236
Onchocerca volvulus 0.0049 0.0178 0.0409
Echinococcus granulosus protein jagged 1 0.0049 0.0178 0.0236
Loa Loa (eye worm) hypothetical protein 0.0182 0.1291 0.1291
Echinococcus granulosus cathepsin L cysteine protease 0.0189 0.1352 0.1788
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0603 0.081
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0287 0.038
Echinococcus granulosus axis inhibition protein axin 0.0039 0.009 0.0119
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0928 0.7556 1
Brugia malayi calpain D 0.01 0.0603 0.0603
Brugia malayi EGF-like domain containing protein 0.0049 0.0178 0.0178
Schistosoma mansoni hypothetical protein 0.005 0.0183 0.0243
Trypanosoma brucei calpain-like protein, putative 0.0331 0.2548 0.739
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0075 0.0399 0.1474
Loa Loa (eye worm) hypothetical protein 0.0072 0.0371 0.0371
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Brugia malayi Cytochrome P450 family protein 0.0053 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0123 0.0796 0.0796
Plasmodium falciparum plasmepsin X 0.0327 0.2509 0.9459
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.005 0.0183 0.0212
Toxoplasma gondii proteasome subunit beta type, putative 0.0155 0.1065 0.3995
Schistosoma mansoni hypothetical protein 0.0182 0.1291 0.1708
Entamoeba histolytica calmodulin, putative 0.005 0.0183 0.0534
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0287 0.038
Giardia lamblia Hypothetical protein 0.005 0.0189 0.0589
Loa Loa (eye worm) hypothetical protein 0.0238 0.1766 0.1766
Echinococcus granulosus glycoprotein Antigen 5 0.0182 0.1291 0.1707
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0259 0.194 0.2568
Leishmania major hypothetical protein, conserved 0.005 0.0183 0.0437
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0287 0.038
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0083 0.0466 0.0617
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.1352 0.3431
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0344 0.2652 0.3507
Onchocerca volvulus 0.0182 0.1291 0.2962
Toxoplasma gondii EGF family domain-containing protein 0.0049 0.0178 0.064
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.009 0.009
Echinococcus multilocularis snurportin 1 0.0308 0.2352 0.3111
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0155 0.1065 0.2678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Echinococcus granulosus cathepsin L 0.0189 0.1352 0.1788
Echinococcus multilocularis notch 0.0049 0.0178 0.0236
Trypanosoma cruzi metacaspase, putative 0.0123 0.0796 0.1084
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.005 0.0183 0.0658
Entamoeba histolytica cysteine proteinase 2 0.0189 0.1352 0.5016
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0111 0.0701 0.1723
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0344 0.2652 1
Onchocerca volvulus 0.0182 0.1291 0.2962
Loa Loa (eye worm) transcriptional regulator 0.0033 0.0044 0.0044
Trypanosoma brucei hypothetical protein 0.01 0.0603 0.1729
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0371 0.0913
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0039 0.009 0.0119
Echinococcus granulosus prolyl endopeptidase 0.0259 0.194 0.2566
Brugia malayi hypothetical protein 0.0126 0.0825 0.0825
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0371 0.2682
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Brugia malayi aspartic protease BmAsp-2, identical 0.0075 0.0399 0.0399
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0111 0.0701 0.2618
Echinococcus granulosus cathepsin L cysteine proteinase 0.0344 0.2652 0.3507
Loa Loa (eye worm) hypothetical protein 0.0182 0.1291 0.1291
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.005 0.0183 0.0365
Echinococcus granulosus caspase 0.0195 0.1402 0.1854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0466 0.1106
Plasmodium vivax aspartyl protease, putative 0.0327 0.2509 0.9459
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0183 0.0506
Brugia malayi hypothetical protein 0.0039 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0111 0.0701 0.0701
Mycobacterium ulcerans NAD-dependent deacetylase 0.0033 0.0044 0.008
Loa Loa (eye worm) hypothetical protein 0.0083 0.0466 0.0466
Onchocerca volvulus 0.0072 0.0371 0.0852
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0083 0.0466 0.1728
Brugia malayi Cathepsin L-like cysteine proteinase 0.0238 0.1766 0.1766
Loa Loa (eye worm) hypothetical protein 0.0238 0.1766 0.1766
Mycobacterium tuberculosis Probable peptidase 0.0103 0.0631 0.1639
Loa Loa (eye worm) notch protein 0.0049 0.0178 0.0178
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0153 0.0418
Plasmodium vivax aspartyl protease, putative 0.0075 0.0399 0.1474
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0142 0.0959 0.24
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0466 0.1106
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0083 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Echinococcus multilocularis regulator of G protein signaling 0.0039 0.009 0.0119
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0155 0.1065 0.285
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.009 0.009
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0153 0.0948
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0128 0.0844 0.1153
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0083 0.0466 0.1728
Onchocerca volvulus Putative cubilin 0.0049 0.0178 0.0409
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.009 0.0119
Trypanosoma brucei kinesin, putative 0.0232 0.1712 0.4956
Onchocerca volvulus 0.0029 0.0009 0.002
Schistosoma mansoni cathepsin B (C01 family) 0.0083 0.0466 0.0617
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0103 0.0631 0.085
Schistosoma mansoni notch 0.0049 0.018 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0466 0.1106
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0344 0.2652 0.6841
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Schistosoma mansoni peroxidasin 0.0419 0.3281 0.4342
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0466 0.1106
Echinococcus granulosus cathepsin b 0.0869 0.7061 0.9337
Giardia lamblia Cathepsin L precursor 0.0083 0.0466 0.1714
Leishmania major cathepsin L-like protease 0.0344 0.2652 0.7675
Onchocerca volvulus Peroxidase homolog 0.0419 0.3281 0.7526
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0273 0.0361
Giardia lamblia Glycogen phosphorylase 0.0106 0.066 0.2503
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0603 0.081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0557 0.0737
Echinococcus granulosus neuronal calcium sensor 0.005 0.0183 0.0243
Toxoplasma gondii EF hand domain-containing protein 0.005 0.0183 0.0658
Trichomonas vaginalis calpain, putative 0.01 0.0603 0.1466
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0331 0.2548 0.3578
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0256 0.0555
Trypanosoma cruzi cysteine peptidase, putative 0.0438 0.3445 0.4855
Onchocerca volvulus Dual oxidase homolog 0.0419 0.3281 0.7526
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0273 0.07
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.066 0.2362
Onchocerca volvulus Prolyl endopeptidase homolog 0.0259 0.194 0.4451
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0083 0.0466 0.1714
Trypanosoma cruzi oligopeptidase b 0.0103 0.0631 0.085
Trypanosoma brucei prolyl oligopeptidase, putative 0.0103 0.0631 0.181
Schistosoma mansoni calpain-2 (C02 family) 0.01 0.0603 0.0798
Giardia lamblia Cathepsin B precursor 0.0326 0.2506 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Loa Loa (eye worm) hypothetical protein 0.0083 0.0466 0.0466
Trichomonas vaginalis calpain, putative 0.01 0.0603 0.1466
Schistosoma mansoni notch 0.0049 0.0178 0.0236
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.009 0.009
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.009 0.0119
Loa Loa (eye worm) calpain 5 0.0232 0.1712 0.1712
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0195 0.1402 0.1854
Loa Loa (eye worm) hypothetical protein 0.0072 0.0371 0.0371
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0155 0.1065 0.3914
Echinococcus multilocularis caspase 0.0195 0.1402 0.1854
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0123 0.0796 0.0796
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0182 0.1291 0.1708
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0928 0.7556 0.9992
Onchocerca volvulus Chorion peroxidase homolog 0.0419 0.3281 0.7526
Onchocerca volvulus 0.0049 0.0178 0.0409
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0466 0.0617
Trichomonas vaginalis centrin, putative 0.005 0.0183 0.0365
Trichomonas vaginalis calmodulin-2, putative 0.005 0.0183 0.0365
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.3722 0.4922
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0033 0.0044 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Plasmodium falciparum cysteine proteinase falcipain 1 0.0189 0.1352 0.5081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0466 0.1106
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0344 0.0456
Leishmania major cathepsin L-like protease 0.0438 0.3445 1
Entamoeba histolytica grainin, putative 0.005 0.0189 0.0556
Toxoplasma gondii cathepsin B 0.0326 0.2506 0.9445
Loa Loa (eye worm) hypothetical protein 0.0122 0.0789 0.0789
Brugia malayi Cadherin domain containing protein 0.0049 0.0178 0.0178
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Trypanosoma cruzi cysteine proteinase, putative 0.0189 0.1352 0.1876
Echinococcus multilocularis cathepsin b 0.0869 0.7061 0.9337
Echinococcus granulosus calpain 5 0.0331 0.2548 0.337
Echinococcus granulosus EF hand domain containing family member A2 0.005 0.0183 0.0243
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0371 0.0491
Schistosoma mansoni neuronal calcium sensor 0.005 0.0183 0.0243
Echinococcus multilocularis tumor protein p63 0.0678 0.5457 0.7216
Echinococcus granulosus programmed cell death protein 0.005 0.0183 0.0243
Trypanosoma cruzi oligopeptidase b 0.0103 0.0631 0.085
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.009
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0083 0.0466 0.1714
Leishmania major centrin, putative,caltractin, putative 0.005 0.0183 0.0437
Schistosoma mansoni integrin alpha-ps 0.0083 0.0462 0.0611
Brugia malayi CXXC zinc finger family protein 0.0029 0.0009 0.0009
Plasmodium falciparum cysteine repeat modular protein 1 0.0069 0.0347 0.1278
Schistosoma mansoni peroxidasin 0.0419 0.3281 0.4342
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.0466 0.0466
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Leishmania major calmodulin-like protein 0.005 0.0183 0.0437
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0869 0.7061 0.9344
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0146 0.0988 0.0988
Trypanosoma cruzi cruzipain precursor, putative 0.0106 0.0654 0.0882
Brugia malayi Cathepsin L-like precursor 0.0106 0.0654 0.0654
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Entamoeba histolytica hypothetical protein, conserved 0.005 0.0189 0.0556
Onchocerca volvulus Neurogenic locus notch homolog 0.0049 0.018 0.0414
Leishmania major cysteine peptidase A (CPA) 0.0344 0.2652 0.7675
Trypanosoma cruzi centrin, putative 0.005 0.0183 0.0212
Echinococcus granulosus caspase 2 0.0244 0.1818 0.2404
Brugia malayi Trypsin-like protease protein 5 0.0182 0.1291 0.1291
Echinococcus granulosus GA binding protein alpha chain 0.0146 0.0988 0.1307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0466 0.1106
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0466 0.1106
Toxoplasma gondii preprocathepsin c precursor, putative 0.0083 0.0466 0.1728
Toxoplasma gondii aspartyl protease ASP1 0.0111 0.0701 0.2618
Trypanosoma brucei protein I/6 0.005 0.0183 0.0506
Trichomonas vaginalis esterase, putative 0.0072 0.0371 0.0858
Brugia malayi RNA, U transporter 1 0.0082 0.0456 0.0456
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0155 0.1065 0.141
Brugia malayi Calcium binding EGF domain containing protein 0.0049 0.0178 0.0178
Onchocerca volvulus 0.0344 0.2652 0.6085
Echinococcus multilocularis integrin alpha 3 0.0142 0.0955 0.1263
Echinococcus multilocularis chromatin regulatory protein sir2 0.0128 0.0844 0.1117
Brugia malayi MH2 domain containing protein 0.0119 0.0766 0.0766
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0371 0.0858
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0287 0.038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0466 0.0617
Leishmania major cathepsin L-like protease 0.0438 0.3445 1
Echinococcus granulosus calmodulin 0.005 0.0183 0.0243
Echinococcus multilocularis programmed cell death protein 0.005 0.0183 0.0243
Echinococcus multilocularis enteropeptidase 0.0182 0.1291 0.1707
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.3281 0.3281
Echinococcus granulosus microtubule associated protein 2 0.0693 0.5582 0.7382
Trypanosoma brucei Component of motile flagella 41 0.005 0.0183 0.0506
Echinococcus multilocularis neurogenic locus notch protein 4 0.0049 0.0178 0.0236
Giardia lamblia Cathepsin L-like protease 0.0083 0.0466 0.1714
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0603 0.081
Loa Loa (eye worm) hypothetical protein 0.0048 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.01 0.0603 0.1729
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1708
Leishmania major hypothetical protein, unknown function 0.01 0.0603 0.1668
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0033 0.0044 0.0132
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Leishmania major sir2-family protein-like protein 0.0033 0.0044 0.0029
Schistosoma mansoni centrin 0.005 0.0183 0.0243
Plasmodium falciparum plasmepsin VIII, putative 0.0075 0.0399 0.1474
Leishmania major calpain family cysteine protease-like protein 0.01 0.0603 0.1668
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0344 0.2652 0.2652
Brugia malayi EGF-like domain containing protein 0.0049 0.0178 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0273 0.1899
Loa Loa (eye worm) hypothetical protein 0.0062 0.0287 0.0287
Echinococcus granulosus cathepsin l1 0.0344 0.2652 0.3507
Loa Loa (eye worm) hypothetical protein 0.0182 0.1291 0.1291
Plasmodium falciparum plasmepsin II 0.0111 0.0701 0.2618
Brugia malayi NAD-dependent deacetylase SIRT1 0.0142 0.0959 0.0959
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.005 0.0183 0.0534
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.3361 0.3361
Plasmodium vivax plasmepsin IV, putative 0.0111 0.0701 0.2618
Brugia malayi EF hand family protein 0.005 0.0189 0.0189
Echinococcus granulosus cathepsin L 0.0083 0.0466 0.0616
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.066 0.2362
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Trypanosoma brucei Calpain-like protein CALP1.3 0.01 0.0603 0.1729
Loa Loa (eye worm) blistered cuticle protein 3 0.0419 0.3281 0.3281
Plasmodium vivax hypothetical protein, conserved 0.005 0.0189 0.0681
Trypanosoma brucei centrin, putative 0.005 0.0183 0.0506
Onchocerca volvulus 0.0099 0.06 0.1377
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0333 0.2559 0.3593
Onchocerca volvulus 0.0344 0.2652 0.6085
Plasmodium vivax aspartyl protease, putative 0.0327 0.2509 0.9459
Loa Loa (eye worm) hypothetical protein 0.0075 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.01 0.0603 0.0603
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0083 0.0466 0.0466
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0083 0.0466 0.1728
Schistosoma mansoni chromatin regulatory protein sir2 0.0142 0.0959 0.1269
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.005 0.0183 0.0212
Plasmodium falciparum proteasome subunit beta type-5 0.0155 0.1065 0.3995
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.066 0.0873
Brugia malayi calcium-binding protein 0.005 0.0183 0.0183
Echinococcus multilocularis GA binding protein alpha chain 0.0146 0.0988 0.1307
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0603 0.1466
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.009 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0796 0.1972
Onchocerca volvulus 0.0075 0.0399 0.0915
Trypanosoma brucei prolyl endopeptidase 0.0259 0.194 0.5619
Giardia lamblia Proteasome subunit beta type 2 0.0045 0.0143 0.0399
Schistosoma mansoni ap endonuclease 0.0058 0.0256 0.0339
Plasmodium vivax vivapain-2 0.0344 0.2652 1
Echinococcus granulosus glycogen phosphorylase 0.0106 0.066 0.0873
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1708
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0287 0.038
Brugia malayi Trypsin family protein 0.0182 0.1291 0.1291
Trypanosoma cruzi cysteine peptidase, putative 0.0344 0.2652 0.3726
Echinococcus multilocularis caspase 3 0.0072 0.0373 0.0494
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0153 0.0418
Loa Loa (eye worm) fibroinase 0.0344 0.2652 0.2652
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0928 0.7556 1
Loa Loa (eye worm) transcriptional regulator 0.0128 0.0844 0.0844
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.0557 0.0557
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0256 0.0315
Echinococcus multilocularis integrin beta 2 0.0233 0.1726 0.2283
Brugia malayi carbohydrate phosphorylase 0.0106 0.066 0.066
Schistosoma mansoni integrin alpha-ps 0.0043 0.0129 0.0171
Echinococcus granulosus neurogenic locus notch protein 0.0049 0.0178 0.0236
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.009 0.009
Loa Loa (eye worm) fli-1 protein 0.0442 0.3474 0.3474
Entamoeba histolytica cysteine proteinase 1, putative 0.0189 0.1352 0.5016
Loa Loa (eye worm) transcriptional regulator 0.0033 0.0044 0.0044
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Brugia malayi Muscle positioning protein 4 0.0049 0.0178 0.0178
Onchocerca volvulus Cathepsin F homolog 0.0344 0.2652 0.6085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Giardia lamblia High cysteine protein 0.0049 0.0178 0.0545
Schistosoma mansoni centrin-related 0.005 0.0183 0.0243
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Plasmodium falciparum serine repeat antigen 5 0.0083 0.0466 0.1728
Loa Loa (eye worm) hypothetical protein 0.0344 0.2652 0.2652
Onchocerca volvulus 0.0049 0.0178 0.0409
Echinococcus multilocularis apoptotic protease activating factor 1 0.0122 0.0789 0.1044
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1708
Trypanosoma cruzi metacaspase, putative 0.0123 0.0796 0.1084
Echinococcus granulosus neurogenic locus protein delta 0.0049 0.0178 0.0236
Onchocerca volvulus 0.0344 0.2652 0.6085
Trypanosoma brucei calpain-like protein, putative 0.0331 0.2548 0.739
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0466 0.0617
Brugia malayi hypothetical protein 0.0039 0.009 0.009
Trypanosoma brucei SIR2-like protein 4, putative 0.0033 0.0044 0.0101
Echinococcus granulosus cathepsin l cysteine peptidase 0.0344 0.2652 0.3507
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0869 0.7061 0.9344
Brugia malayi fibroinase precursor 0.0083 0.0466 0.0466
Echinococcus multilocularis neurogenic locus notch protein 0.0049 0.0178 0.0236
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0244 0.0887
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0009 0.0012
Echinococcus granulosus integrin alpha ps 0.0083 0.0462 0.0611
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.005 0.0183 0.0212
Echinococcus granulosus enteropeptidase 0.0182 0.1291 0.1707
Schistosoma mansoni notch 0.0049 0.0178 0.0236
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0143 0.0258
Brugia malayi cathepsin F-like cysteine proteinase 0.0106 0.0654 0.0654
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0466 0.1106
Onchocerca volvulus 0.0182 0.1291 0.2962
Loa Loa (eye worm) ctsf protein 0.0344 0.2652 0.2652
Brugia malayi Delta serrate ligand family protein 0.0049 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.005 0.0183 0.0183
Echinococcus granulosus neural cadherin 0.0049 0.0178 0.0236
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0273 0.0361
Echinococcus granulosus delta-like protein 1 0.0049 0.0178 0.0236
Echinococcus multilocularis calbindin 32 0.005 0.0189 0.025
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0603 0.1466
Echinococcus multilocularis calmodulin 0.005 0.0183 0.0243
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Brugia malayi Cathepsin L-like precursor 0.0344 0.2652 0.2652
Entamoeba histolytica cysteine protease, putative 0.0083 0.0466 0.1617
Onchocerca volvulus 0.0182 0.1291 0.2962
Schistosoma mansoni cathepsin D (A01 family) 0.0497 0.3935 0.5208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Echinococcus multilocularis integrin alpha ps 0.0083 0.0462 0.0611
Echinococcus multilocularis fat cadherin tumor suppressor 0.0049 0.0178 0.0236
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0466 0.0617
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0083 0.0466 0.1106
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0111 0.0701 0.0928
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0273 0.1899
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.009 0.012
Entamoeba histolytica calmodulin, putative 0.005 0.0183 0.0534
Trypanosoma brucei centrin, putative 0.005 0.0183 0.0506
Trypanosoma brucei oligopeptidase b 0.0103 0.0631 0.181
Schistosoma mansoni calmodulin 0.005 0.0183 0.0243
Loa Loa (eye worm) hypothetical protein 0.0126 0.0825 0.0825
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0466 0.1106
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.005 0.0183 0.0212
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.009 0.0119
Brugia malayi Fli-1 protein 0.0442 0.3474 0.3474
Schistosoma mansoni caspase-7 (C14 family) 0.0195 0.1402 0.1855
Schistosoma mansoni calmodulin 0.005 0.0183 0.0243
Onchocerca volvulus 0.0075 0.0399 0.0915
Schistosoma mansoni cpg binding protein 0.003 0.0023 0.003
Onchocerca volvulus 0.0182 0.1291 0.2962
Leishmania major i/6 autoantigen-like protein 0.005 0.0183 0.0437
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Plasmodium vivax calpain, putative 0.0331 0.2548 0.9607
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0083 0.0466 0.1728
Plasmodium vivax hypothetical protein, conserved 0.0123 0.0796 0.2976
Onchocerca volvulus 0.0122 0.0789 0.1811
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0143 0.0189
Leishmania major cathepsin L-like protease 0.0344 0.2652 0.7675
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0879 0.714 0.9449
Echinococcus granulosus integrin alpha ps 0.004 0.01 0.0132
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0371 0.0913
Echinococcus granulosus integrin alpha 3 0.0142 0.0955 0.1263
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Schistosoma mansoni microtubule-associated protein tau 0.0693 0.5582 0.7388
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.3281 0.3281
Schistosoma mansoni hypothetical protein 0.0049 0.0178 0.0236
Loa Loa (eye worm) hypothetical protein 0.0072 0.0371 0.0371
Schistosoma mansoni hypothetical protein 0.0049 0.0178 0.0236
Mycobacterium tuberculosis Conserved protein 0.0072 0.0371 0.0913
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0155 0.1065 1
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0103 0.0631 0.1751
Echinococcus multilocularis neuronal calcium sensor 0.005 0.0183 0.0243
Echinococcus granulosus caspase 3 0.0072 0.0373 0.0494
Brugia malayi Trypsin family protein 0.0182 0.1291 0.1291
Echinococcus multilocularis calpain family protein 1, d 0.0647 0.5195 0.687
Schistosoma mansoni ap endonuclease 0.0058 0.0256 0.0339
Leishmania major calmodulin-like protein 0.005 0.0183 0.0437
Trypanosoma cruzi metacaspase, putative 0.0123 0.0796 0.1084
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Plasmodium vivax proteasome subunit beta type-2, putative 0.0045 0.0143 0.0504
Echinococcus granulosus cysteine protease 0.0189 0.1352 0.1788
Brugia malayi cathepsin Z-like cysteine proteinase 0.0083 0.0466 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.009 0.012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Mycobacterium tuberculosis Conserved protein 0.0072 0.0371 0.0913
Echinococcus granulosus glycogen phosphorylase 0.0106 0.066 0.0873
Giardia lamblia Hypothetical protein 0.0083 0.0466 0.1714
Brugia malayi cathepsin Z-like cysteine proteinase 0.0083 0.0466 0.0466
Trypanosoma cruzi calmodulin, putative 0.005 0.0183 0.0212
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0256 0.0338
Onchocerca volvulus Cathepsin L homolog 0.0083 0.0466 0.1069
Onchocerca volvulus 0.0344 0.2652 0.6085
Loa Loa (eye worm) hypothetical protein 0.0072 0.0371 0.0371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0796 0.1972
Onchocerca volvulus Peroxidasin homolog 0.0419 0.3281 0.7526
Brugia malayi Protein kinase domain containing protein 0.0069 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0879 0.714 0.714
Schistosoma mansoni calpain (C02 family) 0.0331 0.2548 0.3373
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0256 0.0555
Loa Loa (eye worm) calpain D 0.01 0.0603 0.0603
Plasmodium falciparum serine repeat antigen 6 0.0083 0.0466 0.1728
Entamoeba histolytica cysteine protease, putative 0.0083 0.0466 0.1617
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.005 0.0183 0.0212
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0142 0.0959 0.3717
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.01 0.0603 0.081
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0603 0.081
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0034 0.0034
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0344 0.2652 0.2652
Trypanosoma brucei Calpain-like protein 1.1 0.01 0.0603 0.1729
Loa Loa (eye worm) RGS-3 protein 0.0039 0.009 0.009
Onchocerca volvulus 0.005 0.0183 0.0421
Plasmodium falciparum serine repeat antigen 3 0.0083 0.0466 0.1728
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0083 0.0466 0.1728
Toxoplasma gondii EFHC1, putative 0.005 0.0183 0.0658
Trypanosoma brucei caltractin, putative 0.005 0.0183 0.0506
Loa Loa (eye worm) hypothetical protein 0.0647 0.5195 0.5195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Leishmania major protein kinase, putative 0.005 0.0183 0.0437
Schistosoma mansoni cathepsin F (C01 family) 0.0344 0.2652 0.351
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Plasmodium falciparum serine repeat antigen 2 0.0083 0.0466 0.1728
Schistosoma mansoni cathepsin C 0.0083 0.0466 0.0617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Giardia lamblia Cathepsin B precursor 0.0083 0.0466 0.1714
Schistosoma mansoni gabp alpha 0.0146 0.0988 0.1308
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Schistosoma mansoni notch 0.0049 0.0178 0.0236
Entamoeba histolytica cysteine protease, putative 0.0344 0.2652 1
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0183 0.0365
Brugia malayi calpain family protein 1 0.0879 0.714 0.714
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0155 0.1065 0.1467
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0371 0.2682
Echinococcus multilocularis microtubule associated protein 2 0.0693 0.5582 0.7382
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0796 0.1972
Echinococcus granulosus EF HAND 1 calcium binding site 0.005 0.0183 0.0243
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0045 0.0143 0.0154
Schistosoma mansoni glycogen phosphorylase 0.0106 0.066 0.0874
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0045 0.0143 0.0377
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.7371
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Loa Loa (eye worm) calpain family protein 1 0.0879 0.714 0.714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0273 0.0361
Loa Loa (eye worm) hypothetical protein 0.0547 0.4359 0.4359
Brugia malayi Trypsin family protein 0.0182 0.1291 0.1291
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0033 0.0044 0.0058
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.009
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0083 0.0466 0.0617
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Entamoeba histolytica hypothetical protein 0.0039 0.009 0.0177
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.005 0.0183 0.0243
Onchocerca volvulus 0.0049 0.0178 0.0409
Schistosoma mansoni neuronal calcium sensor 0.005 0.0183 0.0243
Echinococcus granulosus Mastin 0.0182 0.1291 0.1707
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Plasmodium falciparum plasmepsin VII 0.0075 0.0399 0.1474
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0128 0.0844 0.2099
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.009 0.0119
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0049 0.0178 0.0409
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0143 0.0258
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.009 0.012
Onchocerca volvulus 0.005 0.0183 0.0421
Loa Loa (eye worm) hypothetical protein 0.0083 0.0466 0.0466
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0256 0.0717
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0371 0.0913
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.2548 0.3578
Giardia lamblia Cathepsin B precursor 0.0083 0.0466 0.1714
Echinococcus granulosus sarcoplasmic calcium binding protein 0.005 0.0183 0.0243
Echinococcus granulosus snurportin 1 0.0308 0.2352 0.3111
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0083 0.0466 0.0466
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0371 0.0491
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.01 0.0603 0.081
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0344 0.091
Echinococcus granulosus transmembrane protease serine 3 0.0182 0.1291 0.1707
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.01 0.0603 0.1729
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0371 0.0371
Schistosoma mansoni calpain-7 (C02 family) 0.0335 0.2574 0.3407
Loa Loa (eye worm) hypothetical protein 0.0244 0.1818 0.1818
Loa Loa (eye worm) PXA domain-containing protein 0.0039 0.009 0.009
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.066 0.0873
Brugia malayi Calmodulin-like protein 0.005 0.0183 0.0183
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.2548 0.3578
Onchocerca volvulus Cathepsin L homolog 0.0344 0.2652 0.6085
Trypanosoma cruzi kinesin, putative 0.0232 0.1712 0.2388
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0557 0.0737
Schistosoma mansoni hypothetical protein 0.01 0.0603 0.0798
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.009
Trypanosoma brucei calpain, putative 0.01 0.0603 0.1729
Brugia malayi proteasome subunit beta type 2 0.0045 0.0143 0.0143
Schistosoma mansoni mitochondrial solute carrier 0.005 0.0183 0.0243
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0106 0.0654 0.0654
Brugia malayi cathepsin F-like cysteine proteinase 0.0083 0.0466 0.0466
Brugia malayi Proteasome A-type and B-type family protein 0.0155 0.1065 0.1065
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0189 0.1352 0.179
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0153 0.0305
Brugia malayi Cathepsin L-like precursor 0.0344 0.2652 0.2652
Echinococcus multilocularis calpain 0.0331 0.2548 0.337
Echinococcus multilocularis tissue type plasminogen activator 0.0069 0.0347 0.0459
Echinococcus multilocularis cathepsin L cysteine protease 0.0344 0.2652 0.3507
Trypanosoma brucei calmodulin, putative 0.005 0.0189 0.0523
Plasmodium falciparum serine repeat antigen 1 0.0083 0.0466 0.1728
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0344 0.0344
Onchocerca volvulus Slit protein homolog 0.0049 0.0178 0.0409
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0048 0.0169 0.0169
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Trypanosoma brucei centrin-3 0.005 0.0183 0.0506
Schistosoma mansoni regulator of G protein signaling 0.0039 0.009 0.012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Echinococcus multilocularis cathepsin L 0.0083 0.0466 0.0616
Entamoeba histolytica grainin 2 0.005 0.0183 0.0534
Loa Loa (eye worm) hypothetical protein 0.0075 0.0399 0.0399
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.01 0.0603 0.1729
Echinococcus multilocularis neurocalcin 0.005 0.0183 0.0243
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0033 0.0044 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Schistosoma mansoni hypothetical protein 0.004 0.01 0.0133
Brugia malayi programmed cell death protein 6 0.005 0.0183 0.0183
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0128 0.0844 0.243
Echinococcus granulosus tissue type plasminogen activator 0.0069 0.0347 0.0459
Schistosoma mansoni hypothetical protein 0.0049 0.0178 0.0236
Giardia lamblia Cathepsin B precursor 0.0083 0.0466 0.1714
Echinococcus granulosus cathepsin b 0.0869 0.7061 0.9337
Brugia malayi EGF-like domain containing protein 0.0049 0.0178 0.0178
Plasmodium falciparum plasmepsin III 0.0075 0.0399 0.1474
Leishmania major calmodulin, putative 0.005 0.0183 0.0437
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0371 0.0371
Loa Loa (eye worm) calmodulin-like protein 0.005 0.0183 0.0183
Echinococcus multilocularis centrin 2 0.005 0.0183 0.0243
Trichomonas vaginalis calmodulin, putative 0.005 0.0189 0.038
Plasmodium vivax unspecified product 0.0189 0.1352 0.5081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Echinococcus granulosus caspase 8 0.0123 0.0796 0.1053
Schistosoma mansoni calmodulin related calcium binding protein 0.005 0.0183 0.0243
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1729
Plasmodium falciparum centrin-1 0.005 0.0183 0.0658
Entamoeba histolytica hypothetical protein 0.0039 0.009 0.0177
Echinococcus multilocularis integrin alpha ps 0.004 0.01 0.0132
Echinococcus multilocularis protein jagged 1 0.0049 0.0178 0.0236
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0654 0.0882
Brugia malayi proteasome subunit beta type 1 0.0069 0.0344 0.0344
Mycobacterium ulcerans hypothetical protein 0.0072 0.0371 0.2682
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0603 0.1466
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0371 0.0913
Loa Loa (eye worm) hypothetical protein 0.0083 0.0466 0.0466
Plasmodium falciparum plasmepsin IX 0.0327 0.2509 0.9459
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0034 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0287 0.038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0557 0.0737
Echinococcus granulosus cathepsin l1 0.0238 0.1766 0.2335
Brugia malayi hypothetical protein 0.0048 0.0169 0.0169
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Onchocerca volvulus Cathepsin L homolog 0.0344 0.2652 0.6085
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0603 0.1466
Trichomonas vaginalis calcineurin B subunit, putative 0.005 0.0183 0.0365
Trypanosoma brucei calmodulin, putative 0.005 0.0183 0.0506
Echinococcus multilocularis cathepsin b 0.0869 0.7061 0.9337
Trichomonas vaginalis set domain proteins, putative 0.0487 0.3857 1
Schistosoma mansoni integrin beta subunit 0.0186 0.1325 0.1753
Echinococcus granulosus peroxidasin 0.0419 0.3281 0.4338
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0557 0.0737
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Loa Loa (eye worm) hypothetical protein 0.004 0.01 0.01
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0344 0.1151
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0189 0.1352 0.1876
Echinococcus granulosus importin subunit beta 1 0.0029 0.0009 0.0012
Brugia malayi Calcium binding EGF domain containing protein 0.0049 0.0178 0.0178
Brugia malayi Cytochrome P450 family protein 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Plasmodium vivax vivapain-1 0.0189 0.1352 0.5081
Giardia lamblia Cathepsin B precursor 0.0326 0.2506 1
Trypanosoma cruzi cysteine peptidase, putative 0.0189 0.1352 0.1876
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Echinococcus granulosus protein jagged 2 0.0049 0.0178 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0326 0.2506 0.6456
Trypanosoma cruzi metacaspase 5, putative 0.0123 0.0796 0.1084
Entamoeba histolytica cysteine proteinase, putative 0.0189 0.1352 0.5016
Schistosoma mansoni chromatin regulatory protein sir2 0.0033 0.0044 0.0059
Echinococcus granulosus chromatin regulatory protein sir2 0.0128 0.0844 0.1117
Entamoeba histolytica hypothetical protein 0.0039 0.009 0.0177
Loa Loa (eye worm) hypothetical protein 0.0106 0.0654 0.0654
Schistosoma mansoni calcium binding atopy-related autoantigen 0.005 0.0189 0.025
Leishmania major kinesin, putative 0.0232 0.1712 0.492
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Schistosoma mansoni chromatin regulatory protein sir2 0.0128 0.0844 0.1118
Plasmodium vivax metacaspase 1, putative 0.0123 0.0796 0.2976
Brugia malayi Cathepsin L-like precursor 0.0344 0.2652 0.2652
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.3578
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0256 0.0933
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.01 0.0603 0.2247
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0287 0.1051
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0344 0.0787
Onchocerca volvulus 0.0152 0.1041 0.2387
Plasmodium vivax vivapain-2 0.0344 0.2652 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Plasmodium vivax proteasome subunit beta type-5, putative 0.0155 0.1065 0.3995
Trypanosoma brucei metacaspase MCA2 0.0123 0.0796 0.2289
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.739
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0466 0.1106
Echinococcus granulosus neurogenic locus notch protein 0.0049 0.0178 0.0236
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Toxoplasma gondii centrin, putative 0.005 0.0183 0.0658
Schistosoma mansoni memapsin-2 (A01 family) 0.049 0.3881 0.5136
Entamoeba histolytica cysteine protease, putative 0.0083 0.0466 0.1617
Echinococcus multilocularis transmembrane protease serine 3 0.0182 0.1291 0.1707
Plasmodium vivax unspecified product 0.0106 0.0654 0.2437
Leishmania major hypothetical protein, conserved 0.0072 0.0371 0.0988
Loa Loa (eye worm) EF hand family protein 0.005 0.0183 0.0183
Onchocerca volvulus 0.0488 0.3859 0.8853
Onchocerca volvulus 0.0344 0.2652 0.6085
Plasmodium falciparum plasmepsin V 0.019 0.1358 0.5104
Echinococcus multilocularis hypothetical protein 0.0331 0.2548 0.337
Trypanosoma brucei I/6 autoantigen 0.005 0.0183 0.0506
Mycobacterium ulcerans beta-lactamase 0.0072 0.0371 0.2682
Onchocerca volvulus 0.0182 0.1291 0.2962
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0869 0.7061 0.9344
Brugia malayi calpain 7 0.0331 0.2548 0.2548
Schistosoma mansoni calpain-7 (C02 family) 0.0335 0.2574 0.3407
Plasmodium falciparum serine repeat antigen 4 0.0083 0.0466 0.1728
Echinococcus granulosus centrin 2 0.005 0.0183 0.0243
Brugia malayi hypothetical protein 0.0075 0.0399 0.0399
Echinococcus multilocularis Regulator of G protein signaling 20 0.0039 0.009 0.0119
Loa Loa (eye worm) hypothetical protein 0.0069 0.0347 0.0347
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0603 0.1466
Brugia malayi Pre-SET motif family protein 0.0062 0.0287 0.0287
Echinococcus multilocularis fibropellin Ia 0.0049 0.0178 0.0236
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.3578
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0809 0.6551 0.8663
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.009 0.0121
Echinococcus multilocularis EF HAND 1, calcium binding site 0.005 0.0183 0.0243
Brugia malayi Integrin alpha pat-2 precursor 0.0185 0.1317 0.1317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Schistosoma mansoni cpg binding protein 0.0029 0.0009 0.0012
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Onchocerca volvulus 0.005 0.0189 0.0434
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.009 0.012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Schistosoma mansoni chromatin regulatory protein sir2 0.0128 0.0844 0.1118
Plasmodium falciparum serine repeat antigen 9 0.0083 0.0466 0.1728
Mycobacterium ulcerans proteasome PrcB 0.0155 0.1065 0.8203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.1352 0.3431
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0155 0.1065 0.3073
Entamoeba histolytica hypothetical protein 0.0083 0.0466 0.1617
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0574 0.0574
Leishmania major calmodulin, putative 0.005 0.0183 0.0437
Loa Loa (eye worm) glycogen phosphorylase 0.0106 0.066 0.066
Toxoplasma gondii calmodulin CAM1 0.005 0.0189 0.0681
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0796 0.1972
Onchocerca volvulus 0.0547 0.4359 1
Trypanosoma cruzi cruzipain precursor, putative 0.0438 0.3445 0.4855
Plasmodium falciparum cysteine proteinase falcipain 3 0.0344 0.2652 1
Loa Loa (eye worm) aspartyl protease 6 0.0075 0.0399 0.0399
Trypanosoma cruzi calmodulin, putative 0.005 0.0183 0.0212
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0049 0.0178 0.0236
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0371 0.048
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0103 0.0631 0.1639
Giardia lamblia Cysteine protease 0.0083 0.0466 0.1714
Toxoplasma gondii histone deacetylase SIR2 0.0033 0.0044 0.0132
Trypanosoma cruzi major cysteine proteinase, putative 0.0083 0.0466 0.0615
Brugia malayi Kringle domain containing protein 0.0069 0.0347 0.0347
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Giardia lamblia Encystation-specific protease 0.0083 0.0466 0.1714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Brugia malayi beta-lactamase family protein 0.0072 0.0371 0.0371
Trypanosoma brucei cysteine peptidase, putative 0.01 0.0603 0.1729
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.3578
Echinococcus granulosus notch 0.0049 0.0178 0.0236
Entamoeba histolytica cysteine proteinase, putative 0.0189 0.1352 0.5016
Onchocerca volvulus 0.0062 0.0287 0.0659
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.009 0.0121
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.009 0.0119
Schistosoma mansoni hypothetical protein 0.0308 0.2352 0.3113
Giardia lamblia Hypothetical protein 0.0128 0.0844 0.3251
Toxoplasma gondii troponin c, isotype gamma, putative 0.005 0.0183 0.0658
Brugia malayi Blistered cuticle protein 3 0.0419 0.3281 0.3281
Brugia malayi hypothetical protein 0.0152 0.1041 0.1041
Echinococcus multilocularis glycoprotein Antigen 5 0.0182 0.1291 0.1707
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0466 0.1106
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0111 0.0701 0.0701
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0557 0.0737
Trypanosoma cruzi metacaspase 5, putative 0.0123 0.0796 0.1084
Brugia malayi Ets-domain containing protein 0.0146 0.0988 0.0988
Trypanosoma cruzi major cysteine proteinase, putative 0.0178 0.1259 0.1743
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0256 0.0933
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0256 0.0591
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Brugia malayi hypothetical protein 0.0122 0.0789 0.0789
Brugia malayi Cadherin domain containing protein 0.0049 0.0178 0.0178
Toxoplasma gondii kringle domain-containing protein 0.0069 0.0347 0.1278
Loa Loa (eye worm) integrin beta-2 0.0315 0.2412 0.2412
Schistosoma mansoni regulator of G protein signaling 0.0039 0.009 0.012
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0371 0.0858
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Leishmania major cathepsin L-like protease 0.0344 0.2652 0.7675
Leishmania major metacaspase, putative 0.0123 0.0796 0.2233
Echinococcus multilocularis cysteine protease 0.0344 0.2652 0.3507
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.0557 0.0557
Schistosoma mansoni hypothetical protein 0.041 0.3207 0.4244
Schistosoma mansoni regulator of G protein signaling 0.0039 0.009 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0466 0.1106
Toxoplasma gondii aspartyl protease ASP5 0.0114 0.0727 0.2714
Brugia malayi hypothetical protein 0.0471 0.3722 0.3722
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0128 0.0844 0.3068
Schistosoma mansoni cathepsin S (C01 family) 0.0083 0.0466 0.0617
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0103 0.0631 0.4752
Plasmodium vivax serine-repeat antigen (SERA) 0.0083 0.0466 0.1728
Brugia malayi Cathepsin L-like precursor 0.0344 0.2652 0.2652
Plasmodium vivax aspartyl proteinase, putative 0.0111 0.0701 0.2618
Loa Loa (eye worm) TK/ROR protein kinase 0.0069 0.0347 0.0347
Trypanosoma brucei antigen, putative 0.0331 0.2548 0.739
Echinococcus granulosus cpg binding protein 0.003 0.0023 0.003
Leishmania major proteasome beta 2 subunit, putative 0.0045 0.0143 0.0318
Echinococcus granulosus calpain A 0.0929 0.7562 1
Plasmodium vivax vivapain-3 0.0189 0.1352 0.5081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Trichomonas vaginalis hypothetical protein 0.01 0.0603 0.1466
Brugia malayi transcriptional regulator, Sir2 family protein 0.0033 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.009
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.3722 0.4922
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0326 0.2506 0.3517
Trypanosoma brucei calpain, putative 0.01 0.0603 0.1729
Loa Loa (eye worm) hypothetical protein 0.0124 0.0811 0.0811
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0123 0.0796 0.2976
Brugia malayi EGF-like domain containing protein 0.0049 0.0178 0.0178
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.005 0.0183 0.0365
Brugia malayi Pepsin A precursor 0.0075 0.0399 0.0399
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0111 0.0701 0.0927
Leishmania major centrin, putative 0.005 0.0183 0.0437
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0183 0.0365
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0045 0.0143 0.0387
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Echinococcus multilocularis neurogenic locus protein delta 0.0049 0.0178 0.0236
Entamoeba histolytica cysteine protease, putative 0.0083 0.0466 0.1617
Brugia malayi PXA domain containing protein 0.0039 0.009 0.009
Brugia malayi cathepsin B-like cysteine proteinase 0.0869 0.7061 0.7061
Onchocerca volvulus 0.0344 0.2652 0.6085
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0371 0.0913
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0796 0.1972
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Echinococcus granulosus calbindin 32 0.005 0.0189 0.025
Echinococcus multilocularis Glycosyl transferase, family 35 0.0106 0.066 0.0873
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Trichomonas vaginalis myosin light chain 1, putative 0.005 0.0183 0.0365
Brugia malayi Papain family cysteine protease containing protein 0.0189 0.1352 0.1352
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0083 0.0466 0.1728
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0083 0.0466 0.1728
Trypanosoma brucei calpain-like protein, putative 0.0331 0.2548 0.739
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.009 0.0119
Plasmodium falciparum serine repeat antigen 7 0.0083 0.0466 0.1728
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0557 0.0737
Trypanosoma cruzi kinesin, putative 0.0232 0.1712 0.2388
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0273 0.0638
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0347 0.0445
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Echinococcus multilocularis cpg binding protein 0.003 0.0023 0.003
Entamoeba histolytica calpain large subunit domain III containing protein 0.0232 0.1712 0.6396
Toxoplasma gondii ABC1 family protein 0.0072 0.0371 0.1369
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0103 0.0631 0.181
Schistosoma mansoni cathepsin D (A01 family) 0.0497 0.3935 0.5208
Echinococcus multilocularis programmed cell death protein 0.005 0.0183 0.0243
Brugia malayi Cathepsin L-like precursor 0.0238 0.1766 0.1766
Trypanosoma brucei metacaspase 5, putative 0.0123 0.0796 0.2289
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Mycobacterium tuberculosis Conserved protein 0.0072 0.0371 0.0913
Schistosoma mansoni integrin alpha 0.0185 0.1317 0.1742
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0256 0.5
Loa Loa (eye worm) hypothetical protein 0.0102 0.0622 0.0622
Plasmodium vivax plasmepsin V, putative 0.019 0.1358 0.5104
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Trypanosoma cruzi caltractin, putative 0.005 0.0183 0.0212
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0344 0.122
Echinococcus granulosus expressed protein 0.075 0.6058 0.8011
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0033 0.0044 0.0014
Loa Loa (eye worm) hypothetical protein 0.0106 0.0654 0.0654
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Echinococcus granulosus calpain 7 C02 family 0.0331 0.2548 0.337
Onchocerca volvulus Huntingtin homolog 0.0126 0.0825 0.1892
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.009
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0371 0.0913
Brugia malayi GCC2 and GCC3 family protein 0.0049 0.0178 0.0178
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.06 0.0794
Schistosoma mansoni cathepsin s 0.0106 0.0654 0.0865
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Toxoplasma gondii aspartyl protease ASP3 0.0327 0.2509 0.9459
Plasmodium falciparum plasmepsin I 0.0111 0.0701 0.2618
Brugia malayi Eukaryotic aspartyl protease family protein 0.0075 0.0399 0.0399
Plasmodium falciparum serine repeat antigen 8 0.0083 0.0466 0.1728
Trichomonas vaginalis calcineurin B subunit, putative 0.005 0.0189 0.038
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0083 0.0466 0.1728
Toxoplasma gondii hypothetical protein 0.01 0.0603 0.2247
Trypanosoma cruzi I/6 autoantigen, putative 0.005 0.0183 0.0212
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0371 0.1369
Leishmania major cathepsin L-like protease 0.0344 0.2652 0.7675
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Loa Loa (eye worm) hypothetical protein 0.0072 0.0371 0.0371
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Schistosoma mansoni Mername-AA248 (C02 family) 0.0331 0.2548 0.3373
Echinococcus granulosus Glycosyl transferase family 35 0.0106 0.066 0.0873
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0344 0.2652 0.3507
Brugia malayi Cell death protein 3 precursor 0.0244 0.1818 0.1818
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Brugia malayi cathepsin L-like cysteine proteinase 0.0083 0.0466 0.0466
Schistosoma mansoni regulator of G protein signaling 0.0039 0.009 0.012
Leishmania major calpain protease-like protein 0.01 0.0603 0.1668
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0033 0.0044 0.0029
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Trypanosoma brucei Calpain-like protein 2 0.01 0.0603 0.1729
Loa Loa (eye worm) proteasome subunit beta type 2 0.0045 0.0143 0.0143
Onchocerca volvulus 0.0096 0.0574 0.1317
Onchocerca volvulus 0.0049 0.0178 0.0409
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Brugia malayi calpain 5 0.01 0.0603 0.0603
Brugia malayi prolyl oligopeptidase family protein 0.0259 0.194 0.194
Giardia lamblia Cysteine protease 0.0083 0.0466 0.1714
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.009 0.0119
Loa Loa (eye worm) hypothetical protein 0.0099 0.06 0.06
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0466 0.1106
Trichomonas vaginalis calpain, putative 0.01 0.0603 0.1466
Echinococcus multilocularis neurogenic locus notch protein 0.0049 0.0178 0.0236
Brugia malayi hypothetical protein 0.0075 0.0399 0.0399
Leishmania major silent information regulator 2, putative 0.0128 0.0844 0.2375
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0344 0.2652 0.6841
Loa Loa (eye worm) programmed cell death protein 6 0.005 0.0189 0.0189
Entamoeba histolytica calcium binding family protein 0.005 0.0183 0.0534
Loa Loa (eye worm) hypothetical protein 0.0083 0.0466 0.0466
Brugia malayi calpain 5 0.0232 0.1712 0.1712
Onchocerca volvulus Peroxidase homolog 0.0419 0.3281 0.7526
Giardia lamblia Cathepsin B precursor 0.0083 0.0466 0.1714
Entamoeba histolytica cysteine protease, putative 0.0083 0.0466 0.1617
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0371 0.0858
Schistosoma mansoni survival motor neuron protein 0.0096 0.0574 0.076
Toxoplasma gondii histone deacetylase SIR2-like 0.0033 0.0044 0.0132
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Trypanosoma brucei Calpain-like protein 1.2 0.01 0.0603 0.1729
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0259 0.194 0.5588
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0344 0.2652 1
Loa Loa (eye worm) hypothetical protein 0.0471 0.3722 0.3722
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0039 0.009 0.0119
Onchocerca volvulus 0.0419 0.3281 0.7526
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0189 0.1352 0.179
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0033 0.0044 0.0058
Onchocerca volvulus 0.0083 0.0466 0.1069
Echinococcus granulosus dnaJ subfamily B 0.041 0.3207 0.4241
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0256 0.0811
Brugia malayi Pre-SET motif family protein 0.0428 0.3361 0.3361
Brugia malayi Trypsin family protein 0.0182 0.1291 0.1291
Schistosoma mansoni axis inhibition protein axin 0.0039 0.009 0.012
Echinococcus granulosus calpain 0.0331 0.2548 0.337
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Schistosoma mansoni reticulocalbin 0.005 0.0189 0.025
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0273 0.1899
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0103 0.0631 0.085
Trypanosoma cruzi centrin-3 0.005 0.0183 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0438 0.3445 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.1352 0.3909
Brugia malayi Integrin beta pat-3 precursor 0.0315 0.2412 0.2412
Toxoplasma gondii cathepsin CPC2 0.0083 0.0466 0.1728
Trypanosoma cruzi I/6 autoantigen, putative 0.005 0.0183 0.0212
Loa Loa (eye worm) hypothetical protein 0.014 0.0939 0.0939
Echinococcus multilocularis prolyl endopeptidase 0.0259 0.194 0.2566
Brugia malayi Calcium binding EGF domain containing protein 0.0049 0.0178 0.0178
Echinococcus multilocularis dnaJ subfamily B 0.041 0.3207 0.4241
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0039 0.009 0.012
Onchocerca volvulus 0.0344 0.2652 0.6085
Trypanosoma cruzi calpain cysteine peptidase, putative 0.01 0.0603 0.081
Leishmania major cathepsin L-like protease 0.0344 0.2652 0.7675
Leishmania major hypothetical protein, conserved 0.01 0.0603 0.1668
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0298 0.0395
Echinococcus granulosus protein jagged 1 0.0049 0.0178 0.0236
Loa Loa (eye worm) cysteine protease 0.0344 0.2652 0.2652
Trypanosoma cruzi cysteine protease, putative 0.0189 0.1352 0.1876
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0069 0.0347 0.1278
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0123 0.0796 0.2976
Echinococcus multilocularis proteasome (prosome, macropain) 0.0155 0.1065 0.1409
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0183 0.0365
Onchocerca volvulus 0.0419 0.3281 0.7526
Plasmodium vivax aspartyl proteinase, putative 0.0075 0.0399 0.1474
Loa Loa (eye worm) hypothetical protein 0.0145 0.0984 0.0984
Toxoplasma gondii centrin 0.005 0.0183 0.0658
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0143 0.0189
Schistosoma mansoni ef hand domain family member A2 0.005 0.0183 0.0243
Leishmania major hypothetical protein, conserved 0.005 0.0189 0.0455
Schistosoma mansoni chromatin regulatory protein sir2 0.0033 0.0044 0.0059
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Schistosoma mansoni hypothetical protein 0.0122 0.0789 0.1045
Brugia malayi Animal haem peroxidase family protein 0.0419 0.3281 0.3281
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0153 0.0203
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0103 0.0631 0.3748
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0195 0.1402 0.1854
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.3281 0.3281
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0183 0.0365
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Trypanosoma cruzi centrin, putative 0.005 0.0183 0.0212
Giardia lamblia Cathepsin L precursor 0.0083 0.0466 0.1714
Loa Loa (eye worm) hypothetical protein 0.0182 0.1291 0.1291
Echinococcus multilocularis calpain 5 0.0331 0.2548 0.337
Plasmodium falciparum metacaspase 1 0.0123 0.0796 0.2976
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0123 0.0796 0.2976
Mycobacterium ulcerans hypothetical protein 0.0182 0.1291 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0128 0.0844 0.2099
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0083 0.0466 0.1106
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.2352 0.2352
Loa Loa (eye worm) cathepsin B 0.0326 0.2506 0.2506
Echinococcus multilocularis Mastin 0.0182 0.1291 0.1707
Schistosoma mansoni caspase-3 (C14 family) 0.0195 0.1402 0.1855
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Brugia malayi EF hand family protein 0.005 0.0183 0.0183
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0256 0.065
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Brugia malayi cathepsin L-like precursor 0.0238 0.1766 0.1766
Trypanosoma brucei metacaspase 0.0123 0.0796 0.2289
Onchocerca volvulus 0.0072 0.0371 0.0852
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Brugia malayi cathepsin L precursor 0.0083 0.0466 0.0466
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0045 0.0143 0.0188
Echinococcus granulosus neurogenic locus notch protein 4 0.0049 0.0178 0.0236
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0128 0.0844 0.1153
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.009 0.012
Echinococcus granulosus integrin beta 2 0.0233 0.1726 0.2283
Schistosoma mansoni notch 0.0049 0.0178 0.0236
Mycobacterium ulcerans lipase LipD 0.0072 0.0371 0.2682
Brugia malayi hypothetical protein 0.0182 0.1291 0.1291
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.2652 0.6841
Toxoplasma gondii prolyl endopeptidase 0.0259 0.194 0.7305
Brugia malayi Kelch motif family protein 0.0048 0.0169 0.0169
Brugia malayi beta-lactamase 0.0072 0.0371 0.0371
Trypanosoma cruzi metacaspase, putative 0.0123 0.0796 0.1084
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0869 0.7061 0.9344
Plasmodium vivax centrin-1, putative 0.005 0.0183 0.0658
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1708
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0049 0.0178 0.0178
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.3578
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0128 0.0844 0.1117
Brugia malayi Animal haem peroxidase family protein 0.0419 0.3281 0.3281
Trypanosoma brucei metacaspase MCA3 0.0123 0.0796 0.2289
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0183 0.0365
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.7371
Giardia lamblia Cathepsin L-like protease 0.0083 0.0466 0.1714
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0044 0.0132
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.005 0.0183 0.0534
Echinococcus multilocularis EF hand domain containing family member A2 0.005 0.0189 0.025
Trypanosoma brucei Metacaspase-4 0.0123 0.0796 0.2289
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1729
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0869 0.7061 1
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0796 0.1972
Echinococcus granulosus protein jagged 2 0.0049 0.0178 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0466 0.1106
Trypanosoma cruzi prolyl endopeptidase 0.0259 0.194 0.2713
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0039 0.009 0.0121
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0557 0.0737
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0466 0.0617
Echinococcus granulosus Regulator of G protein signaling 20 0.0039 0.009 0.0119
Echinococcus multilocularis expressed protein 0.075 0.6058 0.8011
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0256 0.0338
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0083 0.0466 0.1728
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Schistosoma mansoni hypothetical protein 0.005 0.0183 0.0243
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0083 0.0466 0.1617
Schistosoma mansoni cpg binding protein 0.003 0.0023 0.003
Giardia lamblia Cathepsin L precursor 0.0083 0.0466 0.1714
Brugia malayi EGF-like domain containing protein 0.0049 0.0178 0.0178
Echinococcus granulosus tumor protein p63 0.0678 0.5457 0.7216
Trichomonas vaginalis calcium binding proteins, putative 0.005 0.0183 0.0365
Brugia malayi Cathepsin L-like precursor 0.0344 0.2652 0.2652
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.005 0.0183 0.0243
Entamoeba histolytica cysteine protease, putative 0.0189 0.1352 0.5016
Schistosoma mansoni slit 0.0049 0.0178 0.0236
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0208 0.0208
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0182 0.1291 0.1707
Onchocerca volvulus Glycogen phosphorylase homolog 0.0106 0.066 0.1515
Schistosoma mansoni calpain C (C02 family) 0.0331 0.2548 0.3373
Echinococcus granulosus axis inhibition protein axin 0.0039 0.009 0.0119
Plasmodium falciparum metacaspase-like protein 0.0123 0.0796 0.2976
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.0796 0.1972
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.009 0.0119
Plasmodium falciparum calpain 0.01 0.0603 0.2247
Echinococcus multilocularis protein jagged 2 0.0049 0.0178 0.0236
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0371 0.0858
Echinococcus multilocularis integrin alpha ps 0.0083 0.0462 0.0611
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.009 0.0119
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0123 0.0796 0.1053
Giardia lamblia Cathepsin B precursor 0.0083 0.0466 0.1714
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0033 0.0044 0.0101
Schistosoma mansoni chromatin regulatory protein sir2 0.0128 0.0844 0.1118
Schistosoma mansoni reticulocalbin 0.005 0.0183 0.0243
Giardia lamblia Cysteine protease 0.0083 0.0466 0.1714
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0142 0.0959 0.1268
Brugia malayi Cathepsin L-like precursor 0.0344 0.2652 0.2652
Brugia malayi Papain family cysteine protease containing protein 0.0189 0.1352 0.1352
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.0466 0.0466
Schistosoma mansoni cathepsin F (C01 family) 0.0238 0.1766 0.2337
Schistosoma mansoni notch 0.0049 0.0178 0.0236
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1707
Loa Loa (eye worm) Notch2 0.0049 0.0178 0.0178
Plasmodium vivax unspecified product 0.0083 0.0466 0.1728
Onchocerca volvulus 0.0419 0.3281 0.7526
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0232 0.1712 0.4656
Loa Loa (eye worm) hypothetical protein 0.0182 0.1291 0.1291
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.005 0.0189 0.0221
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0142 0.0959 0.1268
Loa Loa (eye worm) hypothetical protein 0.0043 0.0129 0.0129
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0344 0.0456
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0155 0.1065 0.4148
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0256 0.0256
Schistosoma mansoni hypothetical protein 0.0069 0.0347 0.0459
Schistosoma mansoni regulator of G protein signaling 0.0039 0.009 0.012
Trichomonas vaginalis centrin, putative 0.005 0.0183 0.0365
Entamoeba histolytica calpain family cysteine protease, putative 0.01 0.0603 0.2144
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0256 0.1764
Schistosoma mansoni hypothetical protein 0.0096 0.0574 0.076
Loa Loa (eye worm) hypothetical protein 0.0072 0.0371 0.0371
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0126 0.0825 0.0825
Loa Loa (eye worm) hypothetical protein 0.0109 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Echinococcus granulosus proteasome prosome macropain 0.0155 0.1065 0.1409
Leishmania major cathepsin L-like protease 0.0438 0.3445 1
Trichomonas vaginalis calcium binding protein, putative 0.005 0.0183 0.0365
Trypanosoma cruzi calmodulin, putative 0.005 0.0183 0.0212
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0182 0.1291 0.1707
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.2652 0.6841
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.005 0.0183 0.0506
Schistosoma mansoni rab 0.005 0.0183 0.0243
Echinococcus multilocularis EF hand domain containing family member A2 0.005 0.0183 0.0243
Echinococcus granulosus apoptotic protease activating factor 1 0.0122 0.0789 0.1044
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0273 0.0997
Onchocerca volvulus 0.0069 0.0347 0.0796
Echinococcus multilocularis calpain 7 (C02 family) 0.0331 0.2548 0.337
Schistosoma mansoni cell polarity protein 0.0049 0.0178 0.0236
Loa Loa (eye worm) calpain family protein 1 0.0647 0.5195 0.5195
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.01 0.0603 0.1466
Schistosoma mansoni neuronal calcium sensor 0.005 0.0183 0.0243
Trypanosoma cruzi 20S proteasome subunit 0.0045 0.0143 0.0154
Loa Loa (eye worm) hypothetical protein 0.0259 0.194 0.194
Loa Loa (eye worm) integrin alpha pat-2 0.0285 0.2156 0.2156
Plasmodium vivax serine-repeat antigen (SERA) 0.0083 0.0466 0.1728
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Brugia malayi calpain family protein 1 0.0879 0.714 0.714
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0075 0.0399 0.0399
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0153 0.0418
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0049 0.0178 0.0236
Schistosoma mansoni neuronal calcium sensor 0.005 0.0183 0.0243
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2548 0.7371
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Trypanosoma brucei calpain-like protein, putative 0.0331 0.2548 0.739
Brugia malayi Cathepsin L-like precursor 0.0238 0.1766 0.1766
Brugia malayi hypothetical protein 0.0419 0.3281 0.3281
Onchocerca volvulus Huntingtin homolog 0.0126 0.0825 0.1892
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.2548 0.3578
Schistosoma mansoni cercarial elastase (S01 family) 0.0182 0.1291 0.1708
Schistosoma mansoni caspase-7 (C14 family) 0.0244 0.1818 0.2406
Echinococcus multilocularis cathepsin L 0.0189 0.1352 0.1788
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0238 0.1766 0.4516
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0273 0.0361
Brugia malayi EGF-like domain containing protein 0.0049 0.0178 0.0178
Plasmodium falciparum plasmepsin IV 0.0111 0.0701 0.2618
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0928 0.7556 0.9992
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.009 0.0121
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0106 0.0654 0.0654
Leishmania major proteasome beta 5 subunit, putative 0.0155 0.1065 0.3022
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0155 0.1065 0.1467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0238 0.1766 0.4516
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0766 0.0766
Brugia malayi Integrin alpha cytoplasmic region family protein 0.014 0.0939 0.0939
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0045 0.0143 0.0504
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.01 0.0603 0.081
Loa Loa (eye worm) hypothetical protein 0.0869 0.7061 0.7061
Giardia lamblia Cathepsin B precursor 0.0326 0.2506 1
Schistosoma mansoni laminin gamma-3 chain 0.0049 0.0178 0.0236
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.009 0.0119
Loa Loa (eye worm) hypothetical protein 0.0419 0.3281 0.3281
Loa Loa (eye worm) sirtuin 4 0.0033 0.0044 0.0044
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0083 0.0466 0.1728
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.009 0.0121
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0083 0.0466 0.0617
Schistosoma mansoni septate junction protein 0.0049 0.0178 0.0236
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0033 0.0044 0.0058
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0045 0.0143 0.0504
Echinococcus multilocularis calcium uptake protein 1 0.005 0.0189 0.025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0256 0.0315
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0142 0.0959 0.24
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0083 0.0466 0.0466
Toxoplasma gondii calcium-dependent protein kinase 0.005 0.0189 0.0681
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.1668
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0344 0.0456
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0182 0.1291 0.1708
Schistosoma mansoni hypothetical protein 0.0182 0.1291 0.1708
Chlamydia trachomatis glycogen phosphorylase 0.0106 0.066 0.5
Brugia malayi Animal haem peroxidase family protein 0.0419 0.3281 0.3281
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0049 0.0178 0.0236
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0399 0.0528
Plasmodium vivax SET domain protein, putative 0.0062 0.0287 0.1051
Echinococcus multilocularis protein jagged 1 0.0049 0.0178 0.0236
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.0466 0.0466
Echinococcus multilocularis cathepsin L cysteine protease 0.0344 0.2652 0.3507
Entamoeba histolytica cysteine proteinase, putative 0.0344 0.2652 1
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0111 0.0701 0.0927
Brugia malayi Animal haem peroxidase family protein 0.0419 0.3281 0.3281
Giardia lamblia Cathepsin L precursor 0.0083 0.0466 0.1714
Echinococcus multilocularis calmodulin 0.005 0.0183 0.0243
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.122 1 1
Plasmodium vivax NAD-dependent deacetylase, putative 0.0033 0.0044 0.0132
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0326 0.2506 0.3316
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0344 0.1268
Loa Loa (eye worm) hypothetical protein 0.0142 0.0959 0.0959
Echinococcus multilocularis caspase 2 0.0244 0.1818 0.2404
Echinococcus multilocularis slit 2 protein 0.0049 0.0178 0.0236
Echinococcus granulosus calcium uptake protein 1 0.005 0.0189 0.025
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0128 0.0844 0.3068
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0083 0.0466 0.1728
Entamoeba histolytica cysteine proteinase, putative 0.0189 0.1352 0.5016
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.01 0.0603 0.081
Trichomonas vaginalis calmodulin, putative 0.005 0.0183 0.0365
Leishmania major hypothetical protein, conserved 0.0069 0.0347 0.0917
Entamoeba histolytica calcium-binding protein, putative 0.005 0.0183 0.0534
Echinococcus granulosus calpain A 0.0331 0.2548 0.337
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0083 0.0466 0.1728
Leishmania major calcineurin B subunit, putative 0.005 0.0183 0.0437
Loa Loa (eye worm) hypothetical protein 0.0238 0.1766 0.1766
Schistosoma mansoni glycogen phosphorylase 0.0106 0.066 0.0874
Onchocerca volvulus Cell death protein 3 homolog 0.0244 0.1818 0.4171
Loa Loa (eye worm) hypothetical protein 0.0182 0.1291 0.1291

Activities

Activity type Activity value Assay description Source Reference
clogP = 0.5 Calculated partition coefficient (clogP) ChEMBL. 15056002
IC50 (binding) = 0.016 uM Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay) ChEMBL. 15056002
IC50 (binding) = 0.016 uM Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay) ChEMBL. 15056002
IC50 (binding) = 0.118 uM Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP) ChEMBL. 15056002
IC50 (binding) = 0.118 uM Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP) ChEMBL. 15056002

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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