Detailed information for compound 1097680

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 395.521 | Formula: C21H25N5OS
  • H donors: 2 H acceptors: 2 LogP: 3.77 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)Nc1scc(n1)c1ccnc(c1)NCCN1CCOCC1
  • InChi: 1S/C21H25N5OS/c1-16-3-2-4-18(13-16)24-21-25-19(15-28-21)17-5-6-22-20(14-17)23-7-8-26-9-11-27-12-10-26/h2-6,13-15H,7-12H2,1H3,(H,22,23)(H,24,25)
  • InChiKey: YYXUDXHMKVBKTP-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0303
Brugia malayi Cathepsin L-like precursor 0.0624 0.3752 0.3752
Trypanosoma brucei calpain-like protein, putative 0.0398 0.2331 0.2331
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1207 0.7401 0.7394
Loa Loa (eye worm) fibroinase 0.0624 0.3752 0.3752
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0084 0.0364 0.0971
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0078 0.0329 0.0329
Echinococcus granulosus histone deacetylase 8 0.0042 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0471 0.2794 0.6508
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0084 0.0364 0.0364
Trypanosoma cruzi cysteine peptidase, putative 0.0721 0.436 0.436
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0142 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0196 0.1066 0.1066
Schistosoma mansoni hypothetical protein 0.0421 0.2478 0.2458
Leishmania major histone deacetylase, putative 0.0098 0.0453 0.0453
Loa Loa (eye worm) proteasome subunit beta type 2 0.004 0.0093 0.0093
Trypanosoma cruzi cruzipain precursor, putative 0.0721 0.436 0.436
Echinococcus granulosus dnaJ subfamily B 0.0421 0.2478 0.2478
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0143 0.0117
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0288 0.1644 0.1644
Brugia malayi prolyl oligopeptidase family protein 0.0196 0.1066 0.1066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0093 0.0217
Trypanosoma cruzi kinesin, putative 0.0278 0.1583 0.1583
Toxoplasma gondii proteasome subunit beta type 2, putative 0.004 0.0093 0.0093
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0142 0.0731 0.1949
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0206 0.055
Trypanosoma brucei caltractin, putative 0.0058 0.0202 0.0202
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Brugia malayi proteasome subunit beta type 2 0.004 0.0093 0.0093
Brugia malayi Cytochrome P450 family protein 0.0033 0.0046 0.0046
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0152 0.0406
Trypanosoma brucei protein I/6 0.0058 0.0202 0.0202
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0142 0.0731 0.1703
Loa Loa (eye worm) hypothetical protein 0.004 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.012 0.059 0.1374
Brugia malayi histone deacetylase 3 (HD3) 0.0087 0.0386 0.0386
Leishmania major cathepsin L-like protease 0.0624 0.3752 0.3752
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.005 0.0152 0.027
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0611 0.0586
Leishmania major calmodulin-like protein 0.0058 0.0202 0.0202
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0471 0.2794 0.2775
Loa Loa (eye worm) trypsin family protein 0.0078 0.0329 0.0329
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0142 0.0731 0.1949
Loa Loa (eye worm) hypothetical protein 0.0776 0.4701 0.4701
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0089 0.0063
Trypanosoma cruzi major cysteine proteinase, putative 0.0142 0.0731 0.0731
Schistosoma mansoni memapsin-2 (A01 family) 0.0444 0.2622 0.2602
Trypanosoma brucei centrin-3 0.0058 0.0202 0.0202
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.012 0.059 0.059
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0142 0.0731 0.1949
Echinococcus multilocularis glycogen phosphorylase 0.0115 0.0561 0.0561
Trypanosoma brucei proteasome subunit beta type-2, putative 0.004 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0089 0.0207
Brugia malayi Cathepsin L-like precursor 0.0624 0.3752 0.3752
Entamoeba histolytica glycogenphosphorylase, putative 0.005 0.0152 0.0406
Onchocerca volvulus 0.0058 0.0202 0.0176
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0453 0.0453
Giardia lamblia Cathepsin B precursor 0.0471 0.2794 1
Brugia malayi Papain family cysteine protease containing protein 0.0142 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0624 0.3752 0.3752
Brugia malayi CXXC zinc finger family protein 0.003 0.0026 0.0026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Giardia lamblia Cathepsin L precursor 0.0142 0.0731 0.2617
Schistosoma mansoni hypothetical protein 0.0202 0.1106 0.1083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trypanosoma cruzi oligopeptidase b 0.0662 0.3988 0.3988
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.004 0.0093 0.0248
Echinococcus granulosus glycoprotein Antigen 5 0.0078 0.0329 0.0329
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Plasmodium vivax histone deacetylase 1, putative 0.0087 0.0386 0.1028
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0624 0.3752 1
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0453 0.0453
Echinococcus multilocularis acylamino acid releasing enzyme 0.0196 0.1066 0.1066
Trypanosoma brucei Calpain-like protein 1.1 0.012 0.059 0.059
Trypanosoma cruzi centrin, putative 0.0058 0.0202 0.0202
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0089 0.0207
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0089 0.0089
Mycobacterium tuberculosis Probable peptidase 0.0662 0.3988 0.4449
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1112 0.6803 0.6803
Brugia malayi Cathepsin L-like precursor 0.0624 0.3752 0.3752
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0142 0.0731 0.1949
Plasmodium vivax proteasome subunit beta type-1, putative 0.0065 0.0248 0.066
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.004 0.0093 0.0093
Plasmodium vivax SET domain protein, putative 0.009 0.0406 0.1081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0143 0.0143
Entamoeba histolytica hypothetical protein, conserved 0.0058 0.0206 0.055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.1066 0.2842
Loa Loa (eye worm) hypothetical protein 0.0196 0.1066 0.1066
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.012 0.059 0.059
Echinococcus multilocularis programmed cell death protein 0.0058 0.0202 0.0202
Toxoplasma gondii prolyl endopeptidase 0.1622 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0142 0.0731 0.1703
Loa Loa (eye worm) cathepsin B 0.0471 0.2794 0.2794
Loa Loa (eye worm) hypothetical protein 0.0087 0.0386 0.0386
Plasmodium falciparum histone deacetylase 1 0.0087 0.0386 0.1028
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0089 0.0089
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0142 0.0731 0.2617
Plasmodium falciparum calpain 0.012 0.059 0.1572
Plasmodium vivax unspecified product 0.0338 0.1956 0.5213
Toxoplasma gondii centrin, putative 0.0058 0.0202 0.0202
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0089 0.0089
Giardia lamblia Cysteine protease 0.0142 0.0731 0.2617
Trichomonas vaginalis calpain, putative 0.012 0.059 0.1374
Plasmodium vivax serine-repeat antigen (SERA) 0.0142 0.0731 0.1949
Giardia lamblia Histone deacetylase 0.0087 0.0386 0.138
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0399 0.2338 0.2338
Leishmania major centrin, putative 0.0058 0.0202 0.0202
Toxoplasma gondii troponin c, isotype gamma, putative 0.0058 0.0202 0.0202
Schistosoma mansoni histone deacetylase 0.0087 0.0386 0.036
Loa Loa (eye worm) hypothetical protein 0.0429 0.2527 0.2527
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0371 0.2162 0.2162
Brugia malayi hypothetical protein 0.0078 0.0329 0.0329
Onchocerca volvulus 0.0049 0.0149 0.0123
Leishmania major centrin, putative,caltractin, putative 0.0058 0.0202 0.0202
Schistosoma mansoni centrin-related 0.0058 0.0202 0.0176
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0089 0.0089
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0058 0.0206 0.0206
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0611 0.0611
Plasmodium falciparum serine repeat antigen 1 0.0142 0.0731 0.1949
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0731 0.1703
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0491 0.0491
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.012 0.059 0.059
Giardia lamblia Alanyl dipeptidyl peptidase 0.0196 0.1066 0.3816
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1426 0.8775 1
Schistosoma mansoni glycogen phosphorylase 0.005 0.0152 0.0126
Entamoeba histolytica hypothetical protein, conserved 0.0196 0.1066 0.2842
Loa Loa (eye worm) hypothetical protein 0.1054 0.6442 0.6442
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Loa Loa (eye worm) hypothetical protein 0.004 0.0089 0.0089
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0526 0.3137 0.3137
Echinococcus multilocularis prolyl endopeptidase 0.1622 1 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0142 0.0731 0.0707
Echinococcus multilocularis calpain A 0.1112 0.6807 0.6807
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0058 0.0202 0.0538
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0089 0.0089
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0611 0.0611
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0196 0.1066 0.2484
Echinococcus multilocularis neurocalcin 0.0058 0.0202 0.0202
Echinococcus multilocularis calpain 5 0.0398 0.2331 0.2331
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Brugia malayi Proteasome A-type and B-type family protein 0.0084 0.0364 0.0364
Trypanosoma cruzi 20S proteasome subunit 0.004 0.0093 0.0093
Brugia malayi Cathepsin L-like precursor 0.0429 0.2527 0.2527
Trypanosoma brucei histone deacetylase, putative 0.0098 0.0453 0.0453
Loa Loa (eye worm) EF hand family protein 0.0058 0.0202 0.0202
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0089 0.0089
Loa Loa (eye worm) histone deacetylase 3 0.0087 0.0386 0.0386
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.012 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.004 0.0089 0.0089
Echinococcus granulosus histone deacetylase 1 0.0087 0.0386 0.0386
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.0406 0.0406
Mycobacterium ulcerans putative transglutaminase-like protein 0.0246 0.1383 0.3392
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0142 0.0731 0.0707
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0084 0.0364 0.1304
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0202 0.0176
Onchocerca volvulus 0.0429 0.2527 0.2508
Trichomonas vaginalis conserved hypothetical protein 0.012 0.059 0.1374
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0398 0.2331 0.2331
Echinococcus granulosus axis inhibition protein axin 0.004 0.0089 0.0089
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0399 0.2338 0.2338
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0288 0.1644 0.1644
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0398 0.2331 0.2331
Leishmania major calmodulin, putative 0.0058 0.0202 0.0202
Plasmodium vivax vivapain-3 0.0338 0.1956 0.5213
Brugia malayi Cytochrome P450 family protein 0.0033 0.0046 0.0046
Onchocerca volvulus 0.0078 0.0329 0.0303
Trichomonas vaginalis calmodulin-2, putative 0.0058 0.0202 0.047
Echinococcus multilocularis histone deacetylase 7 0.0098 0.0453 0.0453
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0058 0.0202 0.0538
Entamoeba histolytica glycogen phosphorylase, putative 0.0115 0.0561 0.1494
Plasmodium falciparum serine repeat antigen 3 0.0142 0.0731 0.1949
Brugia malayi Trypsin family protein 0.0078 0.0329 0.0329
Trypanosoma cruzi I/6 autoantigen, putative 0.0058 0.0202 0.0202
Trypanosoma brucei histone deacetylase 2 0.0042 0.0104 0.0104
Echinococcus granulosus axis inhibition protein axin 0.004 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0429 0.2527 0.5887
Entamoeba histolytica calmodulin, putative 0.0058 0.0202 0.0538
Echinococcus multilocularis cysteine protease 0.0624 0.3752 0.3752
Brugia malayi Cathepsin L-like precursor 0.0624 0.3752 0.3752
Loa Loa (eye worm) hypothetical protein 0.0142 0.0731 0.0731
Schistosoma mansoni calmodulin 0.0058 0.0202 0.0176
Trypanosoma cruzi calpain cysteine peptidase, putative 0.012 0.059 0.059
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0453 0.0453
Mycobacterium tuberculosis Conserved hypothetical protein 0.0246 0.1383 0.1428
Echinococcus multilocularis proteasome (prosome, macropain) 0.0084 0.0364 0.0364
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0329
Trichomonas vaginalis calcium binding protein, putative 0.0058 0.0202 0.047
Echinococcus granulosus EF hand domain containing family member A2 0.0058 0.0202 0.0202
Leishmania major cathepsin L-like protease 0.0624 0.3752 0.3752
Echinococcus granulosus cathepsin L 0.0142 0.0731 0.0731
Trichomonas vaginalis calpain, putative 0.012 0.059 0.1374
Schistosoma mansoni rab 0.0058 0.0202 0.0176
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0089 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0143 0.0143
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.1066 0.2842
Loa Loa (eye worm) calpain family protein 1 0.1054 0.6442 0.6442
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Leishmania major hypothetical protein, conserved 0.012 0.059 0.059
Plasmodium vivax calpain, putative 0.0398 0.2331 0.6214
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0658 0.0658
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Brugia malayi prolyl oligopeptidase family protein 0.0526 0.3137 0.3137
Onchocerca volvulus Prolyl endopeptidase homolog 0.1622 1 1
Giardia lamblia Hypothetical protein 0.0142 0.0731 0.2617
Trichomonas vaginalis calmodulin, putative 0.0058 0.0206 0.048
Echinococcus granulosus calpain A 0.1112 0.6807 0.6807
Leishmania major cathepsin L-like protease 0.0721 0.436 0.436
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0624 0.3752 0.3752
Loa Loa (eye worm) histone deacetylase 7A 0.0098 0.0453 0.0453
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0084 0.0364 0.0364
Echinococcus granulosus histone deacetylase 6 0.0098 0.0453 0.0453
Echinococcus multilocularis cathepsin L cysteine protease 0.0624 0.3752 0.3752
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Entamoeba histolytica cysteine protease, putative 0.0142 0.0731 0.1949
Onchocerca volvulus 0.0078 0.0329 0.0303
Brugia malayi hypothetical protein 0.0092 0.0419 0.0419
Loa Loa (eye worm) histone deacetylase 0.0098 0.0453 0.0453
Echinococcus granulosus glycogen phosphorylase 0.0115 0.0561 0.0561
Giardia lamblia Cathepsin B precursor 0.0471 0.2794 1
Brugia malayi hypothetical protein 0.004 0.0089 0.0089
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0093 0.0217
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0084 0.0364 0.0364
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0624 0.3752 0.3752
Leishmania major histone deacetylase, putative 0.0098 0.0453 0.0453
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0093 0.0067
Leishmania major cathepsin L-like protease 0.0721 0.436 0.436
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1054 0.6442 0.6433
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Schistosoma mansoni microtubule-associated protein tau 0.1406 0.8647 0.8644
Schistosoma mansoni calpain-7 (C02 family) 0.0398 0.2331 0.2311
Entamoeba histolytica cysteine protease, putative 0.0624 0.3752 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0611 0.0611
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0104 0.0104
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0089 0.0063
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0329
Giardia lamblia Cathepsin L precursor 0.0142 0.0731 0.2617
Plasmodium falciparum proteasome subunit beta type-5 0.0084 0.0364 0.0971
Schistosoma mansoni histone deacetylase 0.0087 0.0386 0.036
Brugia malayi histone deacetylase 11 0.0042 0.0104 0.0104
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0142 0.0731 0.0731
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0058 0.0202 0.0176
Entamoeba histolytica cysteine protease, putative 0.0142 0.0731 0.1949
Trypanosoma brucei proteasome beta 6 subunit 0.0065 0.0248 0.0248
Schistosoma mansoni hypothetical protein 0.0058 0.0202 0.0176
Echinococcus multilocularis cysteine protease 0.0624 0.3752 0.3752
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0089 0.0089
Giardia lamblia Cathepsin B precursor 0.0142 0.0731 0.2617
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0202 0.0176
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0089 0.0089
Plasmodium falciparum histone deacetylase, putative 0.0098 0.0453 0.1207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trichomonas vaginalis centrin, putative 0.0058 0.0202 0.047
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.012 0.059 0.1374
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0526 0.3137 0.3137
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0526 0.3135 0.3135
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0078 0.0329 0.0329
Schistosoma mansoni hypothetical protein 0.0202 0.1106 0.1083
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0104 0.0104
Brugia malayi Pre-SET motif family protein 0.0625 0.3753 0.3753
Schistosoma mansoni hypothetical protein 0.012 0.059 0.0565
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0329
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0526 0.3137 0.3119
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0254 0.0229
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0089 0.0089
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0058 0.0202 0.047
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0104 0.0104
Brugia malayi Histone deacetylase family protein 0.0098 0.0453 0.0453
Schistosoma mansoni regulator of G protein signaling 0.004 0.0089 0.0063
Echinococcus multilocularis calpain 7 (C02 family) 0.0398 0.2331 0.2331
Trypanosoma brucei Calpain-like protein 1.2 0.012 0.059 0.059
Plasmodium falciparum serine repeat antigen 6 0.0142 0.0731 0.1949
Brugia malayi Cathepsin L-like precursor 0.0196 0.1066 0.1066
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.1348 0.1348
Schistosoma mansoni cpg binding protein 0.0031 0.0037 0.0011
Schistosoma mansoni cathepsin C 0.0142 0.0731 0.0707
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1622 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0406 0.038
Onchocerca volvulus 0.0058 0.0206 0.018
Loa Loa (eye worm) hypothetical protein 0.0092 0.0419 0.0419
Echinococcus granulosus neuronal calcium sensor 0.0058 0.0202 0.0202
Trypanosoma cruzi centrin, putative 0.0058 0.0202 0.0202
Trypanosoma brucei calpain-like protein, putative 0.0398 0.2331 0.2331
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0089 0.0089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0398 0.2331 0.2331
Echinococcus granulosus calmodulin 0.0058 0.0202 0.0202
Plasmodium vivax proteasome subunit beta type-5, putative 0.0084 0.0364 0.0971
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0078 0.0329 0.0329
Brugia malayi Pre-SET motif family protein 0.009 0.0406 0.0406
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0065 0.0248 0.066
Schistosoma mansoni cathepsin s 0.0196 0.1066 0.1042
Trypanosoma cruzi cysteine peptidase, putative 0.0721 0.436 0.436
Schistosoma mansoni cathepsin F (C01 family) 0.0624 0.3752 0.3735
Schistosoma mansoni centrin 0.0058 0.0202 0.0176
Brugia malayi hypothetical protein 0.0241 0.1348 0.1348
Brugia malayi cathepsin L precursor 0.0142 0.0731 0.0731
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0398 0.2331 0.2331
Loa Loa (eye worm) cysteine protease 0.0624 0.3752 0.3752
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trypanosoma cruzi centrin-3 0.0058 0.0202 0.0202
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0089 0.0089
Schistosoma mansoni regulator of G protein signaling 0.004 0.0089 0.0063
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0196 0.1066 0.1066
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0149 0.0149
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus granulosus centrin 2 0.0058 0.0202 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0338 0.1956 0.4556
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0329
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0453 0.0428
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0065 0.0248 0.0248
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0398 0.2331 0.2331
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Loa Loa (eye worm) hypothetical protein 0.0656 0.3952 0.3952
Giardia lamblia Cysteine protease 0.0142 0.0731 0.2617
Loa Loa (eye worm) hypothetical protein 0.0371 0.2162 0.2162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Brugia malayi hypothetical protein 0.004 0.0089 0.0089
Brugia malayi Cathepsin L-like cysteine proteinase 0.0429 0.2527 0.2527
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Plasmodium vivax histone deacetylase, putative 0.0098 0.0453 0.1207
Mycobacterium leprae Conserved hypothetical protein 0.0246 0.1383 0.2812
Leishmania major oligopeptidase b 0.0662 0.3988 0.3988
Brugia malayi Papain family cysteine protease containing protein 0.0624 0.3752 0.3752
Plasmodium falciparum serine repeat antigen 8 0.0142 0.0731 0.1949
Echinococcus multilocularis transmembrane protease serine 3 0.0078 0.0329 0.0329
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0526 0.3137 0.3119
Giardia lamblia Glycogen phosphorylase 0.0115 0.0561 0.2006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0143 0.0143
Brugia malayi cathepsin Z-like cysteine proteinase 0.0142 0.0731 0.0731
Leishmania major cathepsin L-like protease 0.0624 0.3752 0.3752
Brugia malayi calpain D 0.012 0.059 0.059
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0142 0.0731 0.0707
Schistosoma mansoni hypothetical protein 0.0058 0.0202 0.0176
Plasmodium falciparum serine repeat antigen 2 0.0142 0.0731 0.1949
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0303
Leishmania major phospholipase c-like protein 0.0058 0.0202 0.0202
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trichomonas vaginalis calcium binding protein, putative 0.0058 0.0202 0.047
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0386 0.0386
Onchocerca volvulus 0.0058 0.0202 0.0176
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0196 0.1066 0.2842
Loa Loa (eye worm) hypothetical protein 0.0196 0.1066 0.1066
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0288 0.1644 0.1644
Trypanosoma brucei kinesin, putative 0.0278 0.1583 0.1583
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0371 0.2162 0.2162
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0453 0.0453
Leishmania major hypothetical protein, conserved 0.0058 0.0206 0.0206
Brugia malayi EF hand family protein 0.0058 0.0202 0.0202
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0089 0.0089
Giardia lamblia Cathepsin B precursor 0.0142 0.0731 0.2617
Echinococcus multilocularis cathepsin b 0.1207 0.7401 0.7401
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0065 0.0248 0.0577
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Echinococcus multilocularis Transglutaminase 0.0246 0.1383 0.1383
Loa Loa (eye worm) hypothetical protein 0.0062 0.0228 0.0228
Trypanosoma brucei calpain-like protein, putative 0.0398 0.2331 0.2331
Schistosoma mansoni calmodulin 0.0058 0.0202 0.0176
Trypanosoma brucei oligopeptidase b 0.0662 0.3988 0.3988
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0142 0.0731 0.1949
Trypanosoma cruzi prolyl endopeptidase 0.1622 1 1
Trypanosoma cruzi calmodulin, putative 0.0058 0.0202 0.0202
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Brugia malayi Thioredoxin family protein 0.0246 0.1383 0.1383
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0624 0.3752 0.3752
Onchocerca volvulus 0.0711 0.4294 0.4279
Echinococcus multilocularis centrin 2 0.0058 0.0202 0.0202
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0212 0.0212
Echinococcus multilocularis tumor protein p63 0.0348 0.2023 0.2023
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus granulosus cpg binding protein 0.0031 0.0037 0.0037
Echinococcus granulosus cathepsin b 0.1207 0.7401 0.7401
Mycobacterium leprae Conserved hypothetical protein 0.0246 0.1383 0.2812
Toxoplasma gondii histone deacetylase HDAC1 0.0098 0.0453 0.0453
Mycobacterium tuberculosis Hypothetical protein 0.0246 0.1383 0.1428
Schistosoma mansoni cathepsin S (C01 family) 0.0142 0.0731 0.0707
Echinococcus granulosus programmed cell death protein 0.0058 0.0202 0.0202
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0058 0.0202 0.0202
Plasmodium falciparum serine repeat antigen 4 0.0142 0.0731 0.1949
Echinococcus multilocularis cathepsin L 0.0142 0.0731 0.0731
Brugia malayi Cathepsin L-like precursor 0.0624 0.3752 0.3752
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0303
Echinococcus granulosus cathepsin L cysteine proteinase 0.0624 0.3752 0.3752
Echinococcus granulosus prolyl endopeptidase 0.1622 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0611 0.1433
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Leishmania major protein kinase, putative 0.0058 0.0202 0.0202
Brugia malayi Calmodulin-like protein 0.0058 0.0202 0.0202
Trypanosoma cruzi cysteine proteinase, putative 0.0338 0.1956 0.1956
Toxoplasma gondii histone deacetylase HDAC2 0.0087 0.0386 0.0386
Entamoeba histolytica protein kinase, putative 0.0278 0.1583 0.4218
Trypanosoma cruzi kinesin, putative 0.0278 0.1583 0.1583
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.012 0.059 0.059
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0179 0.0179
Echinococcus multilocularis glycogen phosphorylase 0.0115 0.0561 0.0561
Entamoeba histolytica cysteine proteinase, putative 0.0338 0.1956 0.5213
Mycobacterium ulcerans hypothetical protein 0.0078 0.0329 0.0718
Loa Loa (eye worm) hypothetical protein 0.009 0.0406 0.0406
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.012 0.059 0.1374
Trypanosoma brucei calpain, putative 0.012 0.059 0.059
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0058 0.0202 0.0202
Echinococcus granulosus calcium uptake protein 1 0.0058 0.0206 0.0206
Giardia lamblia Cysteine protease 0.0142 0.0731 0.2617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0429 0.2527 0.5887
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0142 0.0731 0.0707
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus multilocularis neuronal calcium sensor 0.0058 0.0202 0.0202
Echinococcus granulosus EF hand domain containing family member A2 0.0058 0.0206 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0142 0.0731 0.1703
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0624 0.3752 0.874
Echinococcus multilocularis cpg binding protein 0.0031 0.0037 0.0037
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0089 0.0063
Loa Loa (eye worm) proteasome subunit beta type 1 0.0065 0.0248 0.0248
Entamoeba histolytica cysteine protease, putative 0.0142 0.0731 0.1949
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0196 0.1066 0.2842
Leishmania major hypothetical protein, unknown function 0.012 0.059 0.059
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0093 0.0093
Echinococcus granulosus Mastin 0.0078 0.0329 0.0329
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0202 0.0202
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0625 0.3753 0.3753
Loa Loa (eye worm) hypothetical protein 0.0058 0.0202 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0089 0.0063
Trypanosoma cruzi cruzipain precursor, putative 0.0196 0.1066 0.1066
Echinococcus granulosus proteasome prosome macropain 0.0084 0.0364 0.0364
Entamoeba histolytica cysteine protease, putative 0.0142 0.0731 0.1949
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1207 0.7401 0.7401
Onchocerca volvulus 0.0624 0.3752 0.3735
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.012 0.059 0.059
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus granulosus calpain 0.0398 0.2331 0.2331
Brugia malayi calpain family protein 1 0.1054 0.6442 0.6442
Loa Loa (eye worm) RGS-3 protein 0.004 0.0089 0.0089
Schistosoma mansoni calmodulin related calcium binding protein 0.0058 0.0202 0.0176
Leishmania major cytochrome p450-like protein 0.0033 0.0046 0.0046
Brugia malayi PXA domain containing protein 0.004 0.0089 0.0089
Onchocerca volvulus 0.0078 0.0329 0.0303
Trypanosoma brucei histone deacetylase 4 0.0098 0.0453 0.0453
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0046 0.0046
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.012 0.059 0.059
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Entamoeba histolytica calpain large subunit domain III containing protein 0.0278 0.1583 0.4218
Brugia malayi cathepsin L-like cysteine proteinase 0.0142 0.0731 0.0731
Trypanosoma brucei Component of motile flagella 41 0.0058 0.0202 0.0202
Leishmania major C-8 sterol isomerase-like protein 0.0371 0.2162 0.2162
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Brugia malayi PXA domain containing protein 0.004 0.0089 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0089 0.0207
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.1348 0.1348
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0142 0.0731 0.0731
Plasmodium vivax centrin-1, putative 0.0058 0.0202 0.0538
Echinococcus granulosus glycogen phosphorylase 0.0115 0.0561 0.0561
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0142 0.0731 0.1949
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Entamoeba histolytica calcium binding family protein 0.0058 0.0202 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0142 0.0731 0.1703
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Loa Loa (eye worm) ctsf protein 0.0624 0.3752 0.3752
Leishmania major calpain family cysteine protease-like protein 0.012 0.059 0.059
Trypanosoma brucei cysteine peptidase C (CPC) 0.0471 0.2794 0.2794
Plasmodium falciparum histone deacetylase 2 0.0098 0.0453 0.1207
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0058 0.0202 0.0202
Schistosoma mansoni cathepsin F (C01 family) 0.0429 0.2527 0.2508
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0142 0.0731 0.1949
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0338 0.1956 0.1935
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0142 0.0731 0.0707
Onchocerca volvulus 0.0246 0.1383 0.1361
Onchocerca volvulus Cathepsin L homolog 0.0624 0.3752 0.3735
Echinococcus multilocularis programmed cell death protein 0.0058 0.0202 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0196 0.1066 0.2484
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0142 0.0731 0.1949
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0026 0.0026
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0288 0.1644 0.1644
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0078 0.0329 0.0303
Echinococcus multilocularis calcium uptake protein 1 0.0058 0.0206 0.0206
Schistosoma mansoni regulator of G protein signaling 0.004 0.0089 0.0063
Entamoeba histolytica cysteine proteinase 2 0.0338 0.1956 0.5213
Plasmodium vivax hypothetical protein, conserved 0.0196 0.1066 0.2842
Loa Loa (eye worm) hypothetical protein 0.0189 0.1027 0.1027
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0046 0.0046
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0386 0.0898
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.0105 0.0105
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0398 0.2331 0.2331
Brugia malayi Histone deacetylase 1 0.0087 0.0386 0.0386
Entamoeba histolytica hypothetical protein 0.004 0.0089 0.0237
Echinococcus granulosus cathepsin l1 0.0624 0.3752 0.3752
Trypanosoma brucei prolyl oligopeptidase, putative 0.0662 0.3988 0.3988
Onchocerca volvulus 0.0624 0.3752 0.3735
Plasmodium falciparum centrin-1 0.0058 0.0202 0.0538
Loa Loa (eye worm) hypothetical protein 0.012 0.059 0.059
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1207 0.7401 0.7394
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0065 0.0248 0.0248
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0624 0.3752 1
Loa Loa (eye worm) prolyl oligopeptidase 0.0526 0.3137 0.3137
Loa Loa (eye worm) hypothetical protein 0.0051 0.0161 0.0161
Entamoeba histolytica cysteine proteinase, putative 0.0624 0.3752 1
Echinococcus multilocularis glycoprotein Antigen 5 0.0078 0.0329 0.0329
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Echinococcus granulosus histone deacetylase 6 0.0098 0.0453 0.0453
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0142 0.0731 0.1949
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.012 0.059 0.059
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.012 0.059 0.059
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0142 0.0731 0.1949
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Giardia lamblia Encystation-specific protease 0.0142 0.0731 0.2617
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0288 0.1644 0.1644
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Leishmania major i/6 autoantigen-like protein 0.0058 0.0202 0.0202
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0338 0.1956 0.1956
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.012 0.059 0.1374
Echinococcus granulosus histone deacetylase 0.0098 0.0453 0.0453
Trypanosoma cruzi caltractin, putative 0.0058 0.0202 0.0202
Leishmania major cathepsin L-like protease 0.0624 0.3752 0.3752
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0084 0.0364 0.0364
Trypanosoma brucei I/6 autoantigen 0.0058 0.0202 0.0202
Giardia lamblia Cathepsin B precursor 0.0142 0.0731 0.2617
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1207 0.7401 0.7394
Loa Loa (eye worm) hypothetical protein 0.0142 0.0731 0.0731
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0202 0.0176
Trypanosoma brucei histone deacetylase 3 0.0098 0.0453 0.0453
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0196 0.1066 0.1066
Plasmodium falciparum serine repeat antigen 7 0.0142 0.0731 0.1949
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0089 0.0207
Entamoeba histolytica calcium-binding protein, putative 0.0058 0.0202 0.0538
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0288 0.1644 0.1644
Giardia lamblia Alanyl dipeptidyl peptidase 0.0196 0.1066 0.3816
Onchocerca volvulus 0.0624 0.3752 0.3735
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Leishmania major cysteine peptidase A (CPA) 0.0624 0.3752 0.3752
Trichomonas vaginalis calcium binding proteins, putative 0.0058 0.0202 0.047
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0142 0.0731 0.1703
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0084 0.0364 0.0246
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0142 0.0731 0.2617
Toxoplasma gondii cathepsin CPC2 0.0142 0.0731 0.0731
Brugia malayi calpain 5 0.0278 0.1583 0.1583
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0089 0.0089
Echinococcus multilocularis geminin 0.0202 0.1106 0.1106
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0143 0.0143
Plasmodium vivax vivapain-2 0.0624 0.3752 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0338 0.1956 0.5213
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1112 0.6803 0.6803
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0065 0.0248 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Trypanosoma cruzi cysteine peptidase, putative 0.0196 0.1066 0.1066
Onchocerca volvulus 0.0624 0.3752 0.3735
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus granulosus transmembrane protease serine 3 0.0078 0.0329 0.0329
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0386 0.0898
Trypanosoma brucei calmodulin, putative 0.0058 0.0206 0.0206
Echinococcus granulosus cathepsin L 0.0338 0.1956 0.1956
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1112 0.6803 0.6795
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0303
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0104 0.0078
Echinococcus granulosus enteropeptidase 0.0078 0.0329 0.0329
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0142 0.0731 0.1703
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0611 0.0586
Echinococcus granulosus Glycosyl transferase family 35 0.0115 0.0561 0.0561
Echinococcus granulosus microtubule associated protein 2 0.1406 0.8647 0.8647
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0142 0.0731 0.1703
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0142 0.0731 0.0731
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0662 0.3988 0.4449
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0046 0.0046
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0065 0.0248 0.0248
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Schistosoma mansoni regulator of G protein signaling 0.004 0.0089 0.0063
Brugia malayi Trypsin family protein 0.0078 0.0329 0.0329
Trichomonas vaginalis set domain proteins, putative 0.0711 0.4293 1
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0196 0.1066 0.1043
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0089 0.0063
Brugia malayi Papain family cysteine protease containing protein 0.0338 0.1956 0.1956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0142 0.0731 0.2617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Echinococcus multilocularis histone deacetylase 0.0098 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0429 0.2527 0.2527
Onchocerca volvulus Glycogen phosphorylase homolog 0.0115 0.0561 0.0536
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0662 0.3988 0.3988
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Schistosoma mansoni calpain C (C02 family) 0.0398 0.2331 0.2311
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.1066 0.2842
Trichomonas vaginalis calpain, putative 0.012 0.059 0.1374
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0152 0.0406
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0329
Echinococcus multilocularis enteropeptidase 0.0078 0.0329 0.0329
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0386 0.0898
Echinococcus granulosus calbindin 32 0.0058 0.0206 0.0206
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Trichomonas vaginalis glycogen phosphorylase, putative 0.0115 0.0561 0.1306
Brugia malayi programmed cell death protein 6 0.0058 0.0202 0.0202
Echinococcus granulosus cysteine protease 0.0338 0.1956 0.1956
Leishmania major centrin, putative 0.0058 0.0202 0.0202
Echinococcus granulosus cathepsin l cysteine peptidase 0.0624 0.3752 0.3752
Mycobacterium ulcerans hypothetical protein 0.0246 0.1383 0.3392
Giardia lamblia Cysteine protease 0.0142 0.0731 0.2617
Onchocerca volvulus Cathepsin F homolog 0.0624 0.3752 0.3735
Leishmania major programmed cell death 6 protein-like protein 0.0058 0.0202 0.0202
Schistosoma mansoni cpg binding protein 0.0031 0.0037 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0288 0.1644 0.1644
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0089 0.0089
Loa Loa (eye worm) prolyl oligopeptidase 0.0196 0.1066 0.1066
Brugia malayi MH2 domain containing protein 0.013 0.0658 0.0658
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0142 0.0731 0.1703
Trypanosoma brucei antigen, putative 0.0398 0.2331 0.2331
Onchocerca volvulus 0.0078 0.0329 0.0303
Brugia malayi fibroinase precursor 0.0142 0.0731 0.0731
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0142 0.0731 0.1703
Brugia malayi Papain family cysteine protease containing protein 0.0142 0.0731 0.0731
Trypanosoma cruzi cysteine protease, putative 0.0338 0.1956 0.1956
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0338 0.1956 0.1935
Trypanosoma brucei mitochondrial calcium uptake 1 0.0058 0.0202 0.0202
Plasmodium vivax proteasome subunit beta type-2, putative 0.004 0.0093 0.0248
Loa Loa (eye worm) hypothetical protein 0.004 0.0089 0.0089
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0662 0.3988 0.3988
Trypanosoma brucei Calpain-like protein 2 0.012 0.059 0.059
Brugia malayi Cathepsin L-like precursor 0.0624 0.3752 0.3752
Loa Loa (eye worm) calpain 5 0.0278 0.1583 0.1583
Loa Loa (eye worm) calpain D 0.012 0.059 0.059
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0058 0.0202 0.0202
Entamoeba histolytica cysteine proteinase, putative 0.0624 0.3752 1
Giardia lamblia Hypothetical protein 0.0142 0.0731 0.2617
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0089 0.0207
Giardia lamblia Cathepsin B precursor 0.0471 0.2794 1
Echinococcus multilocularis calmodulin 0.0058 0.0202 0.0202
Giardia lamblia Transglutaminase/protease, putative 0.0246 0.1383 0.4951
Plasmodium vivax histone deacetylase 2, putative 0.0098 0.0453 0.1207
Trichomonas vaginalis calcineurin B subunit, putative 0.0058 0.0202 0.047
Toxoplasma gondii preprocathepsin c precursor, putative 0.0142 0.0731 0.0731
Onchocerca volvulus 0.0142 0.0731 0.0707
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.009 0.0406 0.038
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0303
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0143 0.0117
Giardia lamblia Cathepsin L precursor 0.0142 0.0731 0.2617
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0338 0.1956 0.1956
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.009 0.0406 0.0406
Echinococcus granulosus cathepsin b 0.1207 0.7401 0.7401
Schistosoma mansoni cathepsin F (C01 family) 0.0624 0.3752 0.3735
Schistosoma mansoni cercarial elastase (S01 family) 0.0078 0.0329 0.0303
Entamoeba histolytica calpain family cysteine protease, putative 0.012 0.059 0.1572
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0142 0.0731 0.0707
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0142 0.0731 0.0707
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0338 0.1956 0.1956
Leishmania major calpain protease-like protein 0.012 0.059 0.059
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0398 0.2331 0.2331
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0142 0.0731 0.1703
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0196 0.1066 0.1043
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Loa Loa (eye worm) hypothetical protein 0.0196 0.1066 0.1066
Onchocerca volvulus 0.0051 0.0161 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0338 0.1956 0.4556
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1622 1 1
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trichomonas vaginalis centrin, putative 0.0058 0.0202 0.047
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0089 0.0089
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0065 0.0248 0.066
Schistosoma mansoni calpain-7 (C02 family) 0.0398 0.2331 0.2311
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0046 0.0046
Brugia malayi Papain family cysteine protease containing protein 0.0142 0.0731 0.0731
Entamoeba histolytica cysteine proteinase, putative 0.0338 0.1956 0.5213
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus multilocularis cathepsin L 0.0338 0.1956 0.1956
Trypanosoma brucei prolyl endopeptidase 0.1622 1 1
Onchocerca volvulus 0.0656 0.3952 0.3936
Onchocerca volvulus 0.0078 0.0329 0.0303
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0142 0.0731 0.2617
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Plasmodium falciparum cysteine proteinase falcipain 1 0.0338 0.1956 0.5213
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0058 0.0202 0.047
Brugia malayi Trypsin family protein 0.0078 0.0329 0.0329
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0142 0.0731 0.1703
Echinococcus granulosus histone deacetylase 7 0.0098 0.0453 0.0453
Brugia malayi prolyl oligopeptidase family protein 0.0196 0.1066 0.1066
Toxoplasma gondii calcium-dependent protein kinase 0.0058 0.0206 0.0206
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0662 0.3988 1
Brugia malayi calpain 5 0.012 0.059 0.059
Echinococcus multilocularis EF hand domain containing family member A2 0.0058 0.0206 0.0206
Echinococcus granulosus cathepsin l1 0.0429 0.2527 0.2527
Echinococcus multilocularis cathepsin L cysteine protease 0.0624 0.3752 0.3752
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0084 0.0364 0.0848
Leishmania major calcineurin B subunit, putative 0.0058 0.0202 0.0202
Giardia lamblia Cathepsin L precursor 0.0142 0.0731 0.2617
Echinococcus multilocularis Glycosyl transferase, family 35 0.0115 0.0561 0.0561
Entamoeba histolytica hypothetical protein 0.004 0.0089 0.0237
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0196 0.1066 0.2484
Loa Loa (eye worm) hypothetical protein 0.0156 0.0817 0.0817
Toxoplasma gondii cathepsin CPL 0.0624 0.3752 0.3752
Giardia lamblia Cathepsin L precursor 0.0142 0.0731 0.2617
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0093 0.0067
Brugia malayi cathepsin F-like cysteine proteinase 0.0142 0.0731 0.0731
Trichomonas vaginalis calcium binding protein, putative 0.0058 0.0202 0.047
Schistosoma mansoni cathepsin B (C01 family) 0.0142 0.0731 0.0707
Trichomonas vaginalis myosin light chain 1, putative 0.0058 0.0202 0.047
Plasmodium vivax histone deacetylase, putative 0.0042 0.0104 0.0276
Giardia lamblia Hypothetical protein 0.0246 0.1383 0.4951
Giardia lamblia Cathepsin B precursor 0.0142 0.0731 0.2617
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0065 0.0248 0.0248
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Loa Loa (eye worm) hypothetical protein 0.004 0.0089 0.0089
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0142 0.0731 0.1949
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Brugia malayi Trypsin family protein 0.0078 0.0329 0.0329
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0078 0.0329 0.0329
Brugia malayi prolyl oligopeptidase family protein 0.0288 0.1644 0.1644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Echinococcus granulosus EF HAND 1 calcium binding site 0.0058 0.0202 0.0202
Leishmania major calmodulin-like protein 0.0058 0.0202 0.0202
Giardia lamblia Cathepsin L-like protease 0.0142 0.0731 0.2617
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0065 0.0248 0.0248
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0611 0.0532
Trichomonas vaginalis hypothetical protein 0.012 0.059 0.1374
Plasmodium falciparum serine repeat antigen 9 0.0142 0.0731 0.1949
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0104
Schistosoma mansoni calpain (C02 family) 0.0398 0.2331 0.2311
Schistosoma mansoni glycogen phosphorylase 0.0115 0.0561 0.0536
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0142 0.0731 0.1703
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Toxoplasma gondii EFHC1, putative 0.0058 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.1622 1 1
Schistosoma mansoni hypothetical protein 0.0078 0.0329 0.0303
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Loa Loa (eye worm) hypothetical protein 0.004 0.0089 0.0089
Trypanosoma cruzi oligopeptidase b 0.0662 0.3988 0.3988
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Echinococcus multilocularis calpain 0.0398 0.2331 0.2331
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0089 0.0089
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0058 0.0202 0.0202
Trypanosoma brucei Calpain-like protein CALP1.3 0.012 0.059 0.059
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0161 0.0135
Brugia malayi histone deacetylase 1 (HD1) 0.0087 0.0386 0.0386
Brugia malayi calpain family protein 1 0.1054 0.6442 0.6442
Echinococcus multilocularis hypothetical protein 0.0398 0.2331 0.2331
Entamoeba histolytica cysteine proteinase, putative 0.0338 0.1956 0.5213
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0338 0.1956 0.1935
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.004 0.0093 0.0093
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0662 0.3988 0.3988
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0142 0.0731 0.0707
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0089 0.0063
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0089 0.0089
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0471 0.2794 0.2794
Toxoplasma gondii cathepsin CPC1 0.0142 0.0731 0.0731
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0386 0.0898
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0104 0.0078
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.009 0.0406 0.0406
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0143 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0142 0.0731 0.1703
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0058 0.0202 0.0202
Loa Loa (eye worm) calpain 0.0398 0.2331 0.2331
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0104 0.0078
Mycobacterium tuberculosis Conserved hypothetical protein 0.0246 0.1383 0.1428
Entamoeba histolytica cysteine proteinase, putative 0.0429 0.2527 0.6736
Entamoeba histolytica calmodulin, putative 0.0058 0.0202 0.0538
Plasmodium vivax serine-repeat antigen (SERA) 0.0142 0.0731 0.1949
Brugia malayi cathepsin Z-like cysteine proteinase 0.0142 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0329
Echinococcus multilocularis calpain family protein 1, d 0.0776 0.4701 0.4701
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0089 0.0207
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.012 0.059 0.059
Schistosoma mansoni reticulocalbin 0.0058 0.0202 0.0176
Echinococcus granulosus expressed protein 0.077 0.4662 0.4662
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0058 0.0202 0.0202
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.0406 0.0406
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0143 0.0143
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0624 0.3752 0.874
Loa Loa (eye worm) hypothetical protein 0.0058 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0142 0.0731 0.0731
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0142 0.0731 0.0707
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0624 0.3752 0.3752
Entamoeba histolytica hypothetical protein 0.0142 0.0731 0.1949
Brugia malayi cathepsin F-like cysteine proteinase 0.0196 0.1066 0.1066
Trypanosoma brucei centrin, putative 0.0058 0.0202 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0142 0.0731 0.1949
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0288 0.1644 0.1622
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0089 0.0089
Schistosoma mansoni calpain-2 (C02 family) 0.012 0.059 0.0565
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0196 0.1066 0.1066
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0658 0.0658
Giardia lamblia Cathepsin L-like protease 0.0142 0.0731 0.2617
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0142 0.0731 0.1949
Trypanosoma cruzi cysteine peptidase, putative 0.0624 0.3752 0.3752
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0196 0.1066 0.1066
Plasmodium vivax unspecified product 0.0142 0.0731 0.1949
Toxoplasma gondii proteasome subunit beta type, putative 0.0084 0.0364 0.0364
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0386 0.0898
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0329
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0089 0.0207
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.012 0.059 0.059
Schistosoma mansoni axis inhibition protein axin 0.004 0.0089 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Loa Loa (eye worm) hypothetical protein 0.0934 0.5694 0.5694
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0662 0.3988 0.3988
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0611 0.1433
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0471 0.2794 0.2794
Toxoplasma gondii hypothetical protein 0.0196 0.1066 0.1066
Brugia malayi hypothetical protein 0.0156 0.0817 0.0817
Trypanosoma brucei hypothetical protein 0.012 0.059 0.059
Giardia lamblia Cathepsin L precursor 0.0142 0.0731 0.2617
Echinococcus multilocularis cathepsin b 0.1207 0.7401 0.7401
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Brugia malayi cathepsin B-like cysteine proteinase 0.1207 0.7401 0.7401
Brugia malayi calpain 7 0.0398 0.2331 0.2331
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0399 0.2338 0.2318
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0058 0.0202 0.0202
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0089 0.0089
Leishmania major proteasome beta 5 subunit, putative 0.0084 0.0364 0.0364
Echinococcus multilocularis calmodulin 0.0058 0.0202 0.0202
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0386 0.0386
Echinococcus multilocularis EF hand domain containing family member A2 0.0058 0.0202 0.0202
Trichomonas vaginalis glycogen phosphorylase, putative 0.0115 0.0561 0.1306
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0104 0.0104
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Entamoeba histolytica grainin, putative 0.0058 0.0206 0.055
Leishmania major histone deacetylase, putative 0.0087 0.0386 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0202 0.047
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1207 0.7401 0.7394
Onchocerca volvulus 0.0078 0.0329 0.0303
Trypanosoma cruzi calmodulin, putative 0.0058 0.0202 0.0202
Entamoeba histolytica grainin 2 0.0058 0.0202 0.0538
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0089 0.0089
Toxoplasma gondii cathepsin B 0.0471 0.2794 0.2794
Mycobacterium tuberculosis Long conserved protein 0.0246 0.1383 0.1428
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0089 0.0089
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0611 0.0611
Onchocerca volvulus 0.0624 0.3752 0.3735
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0202 0.047
Giardia lamblia Cathepsin B precursor 0.0142 0.0731 0.2617
Entamoeba histolytica hypothetical protein 0.004 0.0089 0.0237
Toxoplasma gondii EF hand domain-containing protein 0.0058 0.0202 0.0202
Toxoplasma gondii calmodulin CAM1 0.0058 0.0206 0.0206
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0046 0.0046
Leishmania major hypothetical protein, conserved 0.0058 0.0202 0.0202
Entamoeba histolytica glycogen phosphorylase, putative 0.0115 0.0561 0.1494
Echinococcus granulosus Transglutaminase 0.0246 0.1383 0.1383
Trypanosoma cruzi cysteine proteinase, putative 0.0338 0.1956 0.1956
Mycobacterium ulcerans transglutaminase family protein 0.0246 0.1383 0.3392
Trypanosoma cruzi cysteine peptidase, putative 0.0338 0.1956 0.1956
Loa Loa (eye worm) hypothetical protein 0.0142 0.0731 0.0731
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.1066 0.1066
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0386 0.0898
Plasmodium falciparum cysteine proteinase falcipain 3 0.0624 0.3752 1
Onchocerca volvulus 0.0624 0.3752 0.3735
Loa Loa (eye worm) programmed cell death protein 6 0.0058 0.0206 0.0206
Schistosoma mansoni hypothetical protein 0.0246 0.1383 0.1361
Trypanosoma brucei histone deacetylase 1 0.0087 0.0386 0.0386
Loa Loa (eye worm) hypothetical protein 0.0429 0.2527 0.2527
Schistosoma mansoni histone deacetylase hda2 0.0104 0.0491 0.0466
Plasmodium falciparum proteasome subunit beta type-2, putative 0.004 0.0093 0.0248
Plasmodium vivax unspecified product 0.0196 0.1066 0.2841
Echinococcus multilocularis expressed protein 0.077 0.4662 0.4662
Loa Loa (eye worm) hypothetical protein 0.1207 0.7401 0.7401
Trypanosoma brucei calpain-like protein, putative 0.0398 0.2331 0.2331
Leishmania major calmodulin, putative 0.0058 0.0202 0.0202
Giardia lamblia Hypothetical protein 0.0058 0.0206 0.0738
Echinococcus multilocularis calbindin 32 0.0058 0.0206 0.0206
Echinococcus multilocularis histone deacetylase 1 0.0087 0.0386 0.0386
Entamoeba histolytica cysteine proteinase, putative 0.0338 0.1956 0.5213
Loa Loa (eye worm) calmodulin-like protein 0.0058 0.0202 0.0202
Echinococcus granulosus proteasome prosome macropain subunit beta 0.004 0.0093 0.0093
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1112 0.6803 0.6795
Toxoplasma gondii hypothetical protein 0.012 0.059 0.059
Schistosoma mansoni ef hand domain family member A2 0.0058 0.0202 0.0176
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Loa Loa (eye worm) calpain family protein 1 0.0776 0.4701 0.4701
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.012 0.059 0.1374
Loa Loa (eye worm) hypothetical protein 0.0241 0.1348 0.1348
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0142 0.0731 0.1703
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0453 0.0453
Mycobacterium tuberculosis Conserved protein 0.0246 0.1383 0.1428
Echinococcus granulosus acylamino acid releasing enzyme 0.0196 0.1066 0.1066
Schistosoma mansoni glycogen phosphorylase 0.0115 0.0561 0.0536
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0143 0.0117
Schistosoma mansoni mitochondrial solute carrier 0.0058 0.0202 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.0721 0.436 0.436
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0381 0.0381
Echinococcus granulosus Dipeptidyl peptidase 9 0.0288 0.1644 0.1644
Loa Loa (eye worm) histone deacetylase 1 0.0087 0.0386 0.0386
Brugia malayi Cytochrome P450 family protein 0.0054 0.0179 0.0179
Leishmania major kinesin, putative 0.0278 0.1583 0.1583
Leishmania major cathepsin L-like protease 0.0721 0.436 0.436
Trichomonas vaginalis calcium binding protein, putative 0.0058 0.0202 0.047
Brugia malayi Trypsin-like protease protein 5 0.0078 0.0329 0.0329
Trichomonas vaginalis peptide N-glycanase, putative 0.0246 0.1383 0.3222
Echinococcus granulosus calpain 7 C02 family 0.0398 0.2331 0.2331
Echinococcus multilocularis histone deacetylase 3 0.0087 0.0386 0.0386
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0065 0.0248 0.0248
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0406 0.038
Echinococcus granulosus cathepsin L cysteine protease 0.0338 0.1956 0.1956
Plasmodium falciparum serine repeat antigen 5 0.0142 0.0731 0.1949
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0386 0.0898
Trypanosoma brucei calmodulin, putative 0.0058 0.0202 0.0202
Entamoeba histolytica histone deacetylase, putative 0.0087 0.0386 0.1028
Trypanosoma cruzi I/6 autoantigen, putative 0.0058 0.0202 0.0202
Onchocerca volvulus 0.009 0.0406 0.038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.012 0.059 0.059
Schistosoma mansoni Mername-AA248 (C02 family) 0.0398 0.2331 0.2311
Brugia malayi Histone deacetylase family protein 0.0098 0.0453 0.0453
Echinococcus granulosus histone deacetylase 6 0.0104 0.0491 0.0491
Mycobacterium ulcerans proteasome PrcB 0.0084 0.0364 0.0808
Entamoeba histolytica cysteine protease, putative 0.0338 0.1956 0.5213
Brugia malayi cathepsin L-like precursor 0.0429 0.2527 0.2527
Leishmania major cathepsin L-like protease 0.0624 0.3752 0.3752
Loa Loa (eye worm) glycogen phosphorylase 0.0115 0.0561 0.0561
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0303
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0406 0.038
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0058 0.0206 0.018
Schistosoma mansoni axis inhibition protein axin 0.004 0.0089 0.0063
Echinococcus granulosus calumenin 0.0058 0.0206 0.0206
Trypanosoma cruzi major cysteine proteinase, putative 0.0239 0.1339 0.1339
Loa Loa (eye worm) hypothetical protein 0.0196 0.1066 0.1066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Echinococcus granulosus calpain A 0.0398 0.2331 0.2331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0142 0.0731 0.1703
Brugia malayi calcium-binding protein 0.0058 0.0202 0.0202
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0453 0.0428
Plasmodium falciparum peptidase, putative 0.0196 0.1066 0.2842
Echinococcus granulosus histone deacetylase 3 0.0087 0.0386 0.0386
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.012 0.059 0.059
Giardia lamblia Proteasome subunit beta type 1 0.0065 0.0248 0.0886
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0058 0.0202 0.0202
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trypanosoma brucei C-8 sterol isomerase, putative 0.0371 0.2162 0.2162
Echinococcus granulosus neurocalcin 0.0058 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0624 0.3752 0.874
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Brugia malayi Cathepsin L-like precursor 0.0429 0.2527 0.2527
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0386 0.0898
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0142 0.0731 0.0731
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0058 0.0202 0.0202
Schistosoma mansoni survival motor neuron protein 0.0049 0.0149 0.0123
Schistosoma mansoni hypothetical protein 0.0049 0.0149 0.0123
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0142 0.0731 0.1949
Entamoeba histolytica cysteine protease, putative 0.0142 0.0731 0.1949
Brugia malayi Papain family cysteine protease containing protein 0.0338 0.1956 0.1956
Trichomonas vaginalis calmodulin, putative 0.0058 0.0202 0.047
Trypanosoma brucei cysteine peptidase, putative 0.012 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0056 0.019 0.019
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0662 0.3988 1
Giardia lamblia Proteasome subunit beta type 2 0.004 0.0093 0.0333
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0142 0.0731 0.1703
Plasmodium vivax vivapain-1 0.0338 0.1956 0.5213
Entamoeba histolytica cysteine protease, putative 0.0142 0.0731 0.1949
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0142 0.0731 0.0731
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0386 0.0898
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0142 0.0731 0.1949
Trypanosoma brucei centrin, putative 0.0058 0.0202 0.0202
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0089 0.0089
Toxoplasma gondii centrin 0.0058 0.0202 0.0202
Trichomonas vaginalis calcineurin B subunit, putative 0.0058 0.0206 0.048
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0084 0.0364 0.0339
Echinococcus multilocularis Mastin 0.0078 0.0329 0.0329
Brugia malayi carbohydrate phosphorylase 0.0115 0.0561 0.0561
Schistosoma mansoni reticulocalbin 0.0058 0.0206 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Brugia malayi proteasome subunit beta type 1 0.0065 0.0248 0.0248
Onchocerca volvulus Cathepsin L homolog 0.0624 0.3752 0.3735
Echinococcus granulosus geminin 0.0202 0.1106 0.1106
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0398 0.2331 0.2331
Chlamydia trachomatis glycogen phosphorylase 0.0115 0.0561 0.5
Schistosoma mansoni neuronal calcium sensor 0.0058 0.0202 0.0176
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0329
Brugia malayi EF hand family protein 0.0058 0.0206 0.0206
Echinococcus multilocularis microtubule associated protein 2 0.1406 0.8647 0.8647
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.2478 0.2478
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0611 0.1433
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0058 0.0202 0.0538
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.012 0.059 0.1374
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0089 0.0089
Onchocerca volvulus 0.0624 0.3752 0.3735
Onchocerca volvulus Cathepsin L homolog 0.0142 0.0731 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0731 0.1703
Schistosoma mansoni regulator of G protein signaling 0.004 0.0089 0.0063
Plasmodium vivax vivapain-2 0.0624 0.3752 1
Trypanosoma cruzi conserved protein 0.012 0.059 0.059
Trypanosoma cruzi calmodulin, putative 0.0058 0.0202 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.1066 0.1066
Onchocerca volvulus 0.0156 0.0817 0.0793
Leishmania major histone deacetylase, putative 0.0087 0.0386 0.0386
Echinococcus granulosus tumor protein p63 0.0348 0.2023 0.2023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Toxoplasma gondii histone deacetylase HDAC3 0.0087 0.0386 0.0386
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0142 0.0731 0.1703
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0721 0.436 0.436
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.012 0.059 0.059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0624 0.3752 0.874
Trypanosoma brucei calpain, putative 0.012 0.059 0.059
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.0329 0.0303
Schistosoma mansoni hypothetical protein 0.0078 0.0329 0.0303
Echinococcus multilocularis calumenin 0.0058 0.0206 0.0206
Echinococcus granulosus calpain 5 0.0398 0.2331 0.2331
Mycobacterium ulcerans hypothetical protein 0.0246 0.1383 0.3392
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1622 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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