Detailed information for compound 1226593

Basic information

Technical information
  • TDR Targets ID: 1226593
  • Name: 6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-(furan-2-y lmethyl)-N-methylquinazolin-4-amine
  • MW: 334.372 | Formula: C19H18N4O2
  • H donors: 0 H acceptors: 3 LogP: 3.47 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1onc(c1c1ccc2c(c1)c(ncn2)N(Cc1ccco1)C)C
  • InChi: 1S/C19H18N4O2/c1-12-18(13(2)25-22-12)14-6-7-17-16(9-14)19(21-11-20-17)23(3)10-15-5-4-8-24-15/h4-9,11H,10H2,1-3H3
  • InChiKey: ZSIIVCZRLGNNHQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-(3,5-dimethylisoxazol-4-yl)-N-(2-furylmethyl)-N-methyl-quinazolin-4-amine
  • 6-(3,5-dimethyl-4-isoxazolyl)-N-(2-furylmethyl)-N-methyl-4-quinazolinamine
  • [6-(3,5-dimethylisoxazol-4-yl)quinazolin-4-yl]-(2-furylmethyl)-methyl-amine
  • 6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-(furan-2-ylmethyl)-N-methyl-quinazolin-4-amine
  • NCGC00011112
  • PCOP-369891

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Homo sapiens hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Brugia malayi hypothetical protein Get druggable targets OG5_131074 All targets in OG5_131074
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131074 All targets in OG5_131074
Loa Loa (eye worm) hypoxia-induced factor 1 Get druggable targets OG5_131074 All targets in OG5_131074
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Brugia malayi hypoxia-induced factor 1 Get druggable targets OG5_131074 All targets in OG5_131074
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Brugia malayi cytochrome P450 cytochrome P450, family 2, subfamily D, polypeptide 6 497 aa 425 aa 32.0 %
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Putative endochitinase 0.0082 0.0526 0.0521
Schistosoma mansoni heat shock protein 0.0032 0.0062 0.008
Brugia malayi Protein kinase domain containing protein 0.0162 0.1288 0.1288
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0069 0.0412 0.0411
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0099 0.0689 0.0782
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0306 0.0305
Schistosoma mansoni protein kinase 0.003 0.0036 0.0045
Trypanosoma brucei casein kinase I, isoform 2 0.0067 0.0392 0.0646
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0116 0.0849 0.1153
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0062 0.0075
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.0014 0.0018
Echinococcus multilocularis dual specificity mitogen activated protein 0.0194 0.1588 0.1803
Loa Loa (eye worm) TK protein kinase 0.003 0.0036 0.0036
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Trypanosoma cruzi NIMA-related kinase, putative 0.0028 0.0019 0.0033
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0216 0.1798 0.2041
Echinococcus multilocularis protein kinase c iota type 0.0069 0.0412 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0226 0.0302
Onchocerca volvulus 0.005 0.0233 0.0228
Echinococcus multilocularis rac serine:threonine kinase 0.0028 0.0019 0.0021
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0067 0.0392 0.0391
Plasmodium falciparum protein kinase, putative 0.0054 0.0262 0.1801
Loa Loa (eye worm) hypothetical protein 0.013 0.098 0.0979
Echinococcus granulosus acetylcholinesterase 0.0404 0.3567 0.4845
Entamoeba histolytica protein kinase, putative 0.0639 0.5786 1
Onchocerca volvulus 0.0029 0.0035 0.003
Loa Loa (eye worm) AGC/PKA protein kinase 0.0116 0.0849 0.0848
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.04 0.0539
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0171 0.1367 0.2362
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0207 0.1712 0.1708
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0035 0.0034
Schistosoma mansoni protein kinase 0.0232 0.1945 0.2639
Echinococcus multilocularis TGF beta receptor type 1 0.0106 0.0759 0.0861
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0062 0.0075
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Echinococcus granulosus serine:threonine protein kinase haspin 0.0806 0.7362 1
Entamoeba histolytica ankyrin repeat protein 0.003 0.0036 0.003
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0307 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0226 0.0302
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Trichomonas vaginalis CMGC family protein kinase 0.0639 0.5786 1
Brugia malayi serine/threonine-protein kinase 6 0.0153 0.12 0.1199
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Leishmania major protein kinase, putative 0.0039 0.0126 0.0217
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Schistosoma mansoni protein tyrosine kinase 0.003 0.0036 0.0045
Loa Loa (eye worm) hypothetical protein 0.03 0.2593 0.2593
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0055 0.0276 0.0313
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0143
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0 0.5
Echinococcus granulosus protein kinase shaggy 0.0134 0.1018 0.1383
Brugia malayi hypothetical protein 0.0093 0.0631 0.0631
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0042 0.0151 0.0172
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0068 0.04 0.0692
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.0036 0.0041
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi Protein kinase domain containing protein 0.0209 0.173 0.173
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.1018 0.1759
Trypanosoma cruzi casein kinase, putative 0.0067 0.0392 0.0677
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.0036 0.0041
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi endochitinase 0.0082 0.0526 0.0525
Mycobacterium tuberculosis Possible chitinase 0.007 0.0413 0.3749
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0143
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0082 0.0528 0.0599
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0216 0.1798 0.2443
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Leishmania major serine/threonine-protein kinase a, putative 0.0028 0.0019 0.0033
Echinococcus granulosus tyrosine kinase 0.005 0.0233 0.0317
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.0036 0.0041
Giardia lamblia Kinase, CMGC CDK 0.0073 0.0446 0.0772
Onchocerca volvulus 0.0068 0.04 0.0395
Echinococcus multilocularis tyrosine kinase 0.005 0.0233 0.0265
Loa Loa (eye worm) hypothetical protein 0.013 0.098 0.0979
Loa Loa (eye worm) hypothetical protein 0.007 0.0413 0.0412
Echinococcus multilocularis neuroglian 0.0114 0.0832 0.0944
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0028 0.0019 0.0033
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2452 0.3331
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.026 0.0349
Loa Loa (eye worm) haspin protein kinase 0.0806 0.7362 0.7361
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0171 0.1373 0.1372
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0063
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Schistosoma mansoni acetylcholinesterase 0.0068 0.04 0.0539
Mycobacterium ulcerans chitinase/cellulase 0.007 0.0413 0.3749
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Entamoeba histolytica methionine aminopeptidase, putative 0.0048 0.0209 0.033
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Echinococcus granulosus acetylcholinesterase 0.0404 0.3567 0.4845
Trichomonas vaginalis CMGC family protein kinase 0.0639 0.5786 1
Echinococcus multilocularis Immunoglobulin 0.0089 0.0592 0.0672
Echinococcus multilocularis activated cdc42 kinase 1 0.022 0.1834 0.2082
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Schistosoma mansoni kinase 0.0076 0.047 0.0634
Loa Loa (eye worm) hypothetical protein 0.0082 0.0534 0.0533
Onchocerca volvulus 0.0092 0.0621 0.0616
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0194 0.1588 0.2745
Brugia malayi Protein kinase domain containing protein 0.0041 0.0146 0.0145
Echinococcus multilocularis peregrin 0.0031 0.0053 0.006
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.088 0.0879
Loa Loa (eye worm) hypothetical protein 0.0089 0.0592 0.0591
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0124
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Trichomonas vaginalis TKL family protein kinase 0.003 0.0042 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0028 0.0023 0.0027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0187 0.0254
Echinococcus multilocularis casein kinase I alpha 0.0067 0.0392 0.0444
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0849 0.0963
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.1184 0.1604
Brugia malayi Temporarily assigned gene name protein 59 0.0058 0.0303 0.0302
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0062 0.0273
Echinococcus granulosus nephrin 0.0029 0.0035 0.0047
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0144 0.0143
Brugia malayi Protein kinase domain containing protein 0.005 0.0233 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Entamoeba histolytica protein kinase, putative 0.0067 0.039 0.0644
Onchocerca volvulus 0.0033 0.0064 0.0059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0183 0.0183
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0112 0.0809 0.0808
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0184 0.0209
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0099 0.0689 0.0782
Loa Loa (eye worm) TK/INSR protein kinase 0.0179 0.1451 0.145
Echinococcus granulosus aurora kinase A 0.0153 0.12 0.163
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0036 0.0036
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0167 0.1517
Loa Loa (eye worm) hypothetical protein 0.0138 0.1063 0.1062
Echinococcus granulosus serine:threonine protein kinase haspin 0.0806 0.7362 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.003 0.0036 0.0041
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.003 0.0036 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0639 0.5786 1
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Echinococcus multilocularis heat shock protein 90 0.0032 0.0062 0.0071
Echinococcus granulosus neuroligin 0.0068 0.04 0.0544
Brugia malayi Tyrosine-protein kinase PR2 0.003 0.0036 0.0036
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi intermediate filament protein 0.0033 0.0064 0.0063
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0187 0.0186
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0062 0.0075
Brugia malayi hypothetical protein 0.0197 0.1617 0.1616
Entamoeba histolytica hypothetical protein, conserved 0.003 0.0036 0.003
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0112 0.0809 0.0808
Loa Loa (eye worm) haspin protein kinase 0.0806 0.7362 0.7361
Schistosoma mansoni protein kinase 0.0153 0.12 0.1626
Brugia malayi Carboxylesterase family protein 0.0404 0.3567 0.3566
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0037
Trypanosoma brucei SNF1-related protein kinases, putative 0.005 0.0226 0.0359
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0639 0.5786 0.5786
Leishmania major protein kinase, putative 0.0153 0.12 0.2074
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.003 0.0036 0.0041
Trypanosoma brucei cdc2-related kinase 1 0.0073 0.0446 0.0741
Onchocerca volvulus 0.0032 0.0063 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0201 0.0268
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0099 0.0689 0.0782
Giardia lamblia Kinase, CMGC CDK 0.0073 0.0446 0.0772
Onchocerca volvulus Slit protein homolog 0.0033 0.0067 0.0062
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0162 0.1288 0.2227
Echinococcus multilocularis 0.0138 0.1063 0.1207
Echinococcus granulosus protein kinase c epsilon type 0.0069 0.0412 0.0559
Schistosoma mansoni tyrosine kinase 0.0071 0.0424 0.0572
Brugia malayi EGF-like domain containing protein 0.0033 0.0067 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0247 0.0331
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.003 0.0036 0.0063
Loa Loa (eye worm) cuticular endochitinase 0.0082 0.0526 0.0525
Echinococcus granulosus lamin dm0 0.0033 0.0064 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0036 0.0045
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.1367 0.2337
Echinococcus multilocularis slit 2 protein 0.0033 0.0067 0.0076
Echinococcus multilocularis cyclin dependent kinase 9 0.0222 0.1855 0.2106
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0052 0.0247 0.0336
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0023 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Schistosoma mansoni protein kinase 0.0194 0.1592 0.2159
Onchocerca volvulus 0.007 0.0419 0.0414
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0054 0.0262 0.0421
Loa Loa (eye worm) microfilarial chitinase 0.0079 0.0505 0.0505
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0055 0.0276 0.0375
Brugia malayi Endochitinase 0.0091 0.0619 0.0618
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Echinococcus multilocularis aurora kinase A 0.0153 0.12 0.1362
Echinococcus multilocularis transfer RNA-Phe 0.0029 0.0035 0.004
Plasmodium falciparum MO15-related protein kinase 0.0171 0.1367 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0045 0.0183 0.0249
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trypanosoma cruzi casein kinase, putative 0.0067 0.0392 0.0677
Giardia lamblia Kinase, CK1 Casein kinase 0.0067 0.0392 0.0677
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Onchocerca volvulus 0.003 0.0036 0.0031
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0171 0.1367 0.1366
Schistosoma mansoni hypothetical protein 0.0058 0.0303 0.0407
Loa Loa (eye worm) serine/threonine protein kinase 0.003 0.0036 0.0036
Brugia malayi hypoxia-induced factor 1 0.0182 0.1473 0.1472
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Brugia malayi initiation factor 2-associated protein. 0.0048 0.0209 0.0208
Leishmania major serine/threonine kinase-like protein, putative 0.0171 0.1367 0.2362
Echinococcus multilocularis rho associated protein kinase 0.0191 0.1564 0.1775
Echinococcus granulosus peregrin 0.0031 0.0053 0.0072
Brugia malayi Protein kinase domain containing protein 0.0094 0.0645 0.0644
Brugia malayi SRC-1 0.0099 0.0689 0.0688
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0134 0.1018 0.1155
Loa Loa (eye worm) hypothetical protein 0.0045 0.0183 0.0183
Schistosoma mansoni tyrosine kinase 0.0097 0.0673 0.091
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0048 0.0209 0.033
Echinococcus multilocularis para nitrobenzyl esterase 0.0068 0.04 0.0454
Echinococcus granulosus tyrosine protein kinase Fyn 0.0099 0.0689 0.0936
Schistosoma mansoni cell adhesion molecule 0.0029 0.0035 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.2819 0.3826
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0162 0.1288 0.1288
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Echinococcus granulosus tyrosine protein kinase otk 0.0041 0.0144 0.0196
Loa Loa (eye worm) hypothetical protein 0.0088 0.0584 0.0583
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0194 0.1588 0.1588
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0052 0.0247 0.0246
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma cruzi SNF1-related protein kinases, putative 0.005 0.0226 0.0391
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0218 0.1816 0.2467
Brugia malayi Tyrosine-protein kinase abl-1 0.0147 0.1144 0.1143
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0209 0.0362
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0028 0.0019 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Schistosoma mansoni protein kinase 0.003 0.0036 0.0045
Entamoeba histolytica tyrosin kinase, putative 0.003 0.0036 0.003
Onchocerca volvulus Putative endochitinase 0.0091 0.0619 0.0614
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0031 0.0035
Plasmodium falciparum phd finger protein, putative 0.0029 0.0031 0.0088
Echinococcus granulosus tyrosine protein kinase 0.003 0.0036 0.0049
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.003 0.0036 0.0036
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0067 0.039 0.0644
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0124
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0076 0.047 0.0469
Echinococcus granulosus lamin 0.0033 0.0064 0.0087
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0068 0.04 0.0544
Brugia malayi Protein kinase c protein 2 0.0041 0.0146 0.0145
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Echinococcus multilocularis acetylcholinesterase 0.0404 0.3567 0.4048
Schistosoma mansoni cell adhesion molecule 0.0045 0.0183 0.0244
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0143 0.111 0.126
Giardia lamblia Kinase, CMGC DYRK 0.0639 0.5786 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Schistosoma mansoni protein kinase C mu 0.0112 0.0809 0.1095
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Loa Loa (eye worm) initiation factor 2-associated protein 0.0048 0.0209 0.0208
Echinococcus multilocularis casein kinase I alpha 0.0067 0.0392 0.0444
Echinococcus multilocularis protein tyrosine kinase 0.032 0.2777 0.3151
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0073 0.0446 0.0606
Giardia lamblia Aurora kinase 0.0153 0.12 0.2074
Schistosoma mansoni protein kinase 0.003 0.0036 0.0045
Onchocerca volvulus 0.0088 0.0584 0.0579
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Schistosoma mansoni single-minded 0.0059 0.0311 0.0418
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Trypanosoma cruzi protein kinase, putative 0.003 0.0036 0.0063
Trypanosoma cruzi cdc2-related kinase 3 0.0073 0.0446 0.0772
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0048 0.0209 0.0362
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0134 0.1018 0.1017
Schistosoma mansoni protein kinase 0.0112 0.0814 0.1101
Schistosoma mansoni protein kinase 0.0194 0.1588 0.2154
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0038 0.0118 0.0155
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0064 0.0063
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.088 0.0879
Loa Loa (eye worm) haspin protein kinase 0.0829 0.7587 0.7587
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0071 0.0422 0.0421
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Schistosoma mansoni tyrosine kinase 0.005 0.0233 0.0312
Entamoeba histolytica cell division protein kinase 2, putative 0.022 0.1832 0.3143
Trypanosoma cruzi aurora B kinase, putative 0.0153 0.12 0.2074
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0232 0.1945 0.2643
Brugia malayi Furin-like cysteine rich region family protein 0.0097 0.0673 0.0673
Loa Loa (eye worm) AGC/PKN protein kinase 0.0052 0.0247 0.0246
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0153 0.12 0.2048
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0276 0.0375
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0038 0.0118 0.016
Entamoeba histolytica cell division protein kinase 2, putative 0.0073 0.0446 0.0741
Giardia lamblia Protein 21.1 0.003 0.0036 0.0063
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0318 0.0432
Schistosoma mansoni tyrosine-protein kinase fps85d 0.003 0.0036 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0194 0.1592 0.1807
Loa Loa (eye worm) hypothetical protein 0.0067 0.039 0.0389
Brugia malayi Carboxylesterase family protein 0.0068 0.04 0.0399
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0446 0.0772
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.1473 0.1472
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Echinococcus multilocularis roundabout 2 0.0134 0.1019 0.1157
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0035 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0221 0.0295
Echinococcus granulosus lysine specific demethylase 5A 0.0096 0.066 0.0897
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0028 0.0019 0.0033
Trichomonas vaginalis STE family protein kinase 0.0142 0.1099 0.1899
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0116 0.0849 0.5211
Entamoeba histolytica protein kinase, putative 0.0153 0.12 0.2048
Loa Loa (eye worm) TK/DDR protein kinase 0.003 0.0036 0.0036
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0121 0.0164
Onchocerca volvulus 0.0191 0.1564 0.1559
Loa Loa (eye worm) carboxylesterase 0.0404 0.3567 0.3566
Schistosoma mansoni protein kinase 0.0194 0.1592 0.2159
Loa Loa (eye worm) hypothetical protein 0.007 0.0419 0.0418
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0036 0.0036
Schistosoma mansoni intermediate filament proteins 0.0033 0.0064 0.0082
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.0036 0.003
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0106 0.0759 0.0861
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0412 0.0555
Echinococcus granulosus tyrosine protein kinase pr2 0.003 0.0036 0.0049
Schistosoma mansoni hypothetical protein 0.0035 0.009 0.0118
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Mycobacterium ulcerans carboxylesterase, LipT 0.0068 0.04 0.3638
Plasmodium vivax tyrosine kinase-like protein, putative 0.003 0.0036 0.011
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Echinococcus multilocularis roundabout 2 0.0045 0.0183 0.0208
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.0036 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Schistosoma mansoni tyrosine kinase 0.0179 0.1451 0.1967
Trichomonas vaginalis spcc417.12 protein, putative 0.0068 0.04 0.0692
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0062 0.0108
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.6251 0.7095
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0218 0.1816 0.2061
Echinococcus granulosus protein kinase 0.003 0.0036 0.0049
Leishmania major folate/biopterin transporter, putative 0.0028 0.0019 0.0033
Onchocerca volvulus 0.0032 0.0063 0.0058
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0159 0.1259 0.1258
Onchocerca volvulus Tyrosine kinase homolog 0.0413 0.3657 0.3654
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Brugia malayi SH2 domain containing protein 0.005 0.0233 0.0232
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0099 0.0693 0.0786
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.0019 0.0021
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi plexin A 0.0039 0.012 0.0119
Loa Loa (eye worm) acetylcholinesterase 1 0.0404 0.3567 0.3566
Loa Loa (eye worm) hypothetical protein 0.019 0.1554 0.1553
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0031 0.0042
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0048 0.0209 0.0204
Brugia malayi RhoGAP domain containing protein 0.0038 0.0118 0.0117
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.0026 0.0004 0.0005
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.003 0.0036 0.0036
Echinococcus multilocularis Immunoglobulin 0.0089 0.0592 0.0672
Schistosoma mansoni hemicentin 0.0029 0.0035 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0031 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0144 0.0143
Echinococcus granulosus contactin 0.0045 0.0183 0.0249
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.005 0.0226 0.0391
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Echinococcus granulosus raf serine:threonine protein kinase 0.0047 0.0201 0.0273
Brugia malayi Immunoglobulin I-set domain containing protein 0.0093 0.0631 0.0631
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.0036 0.003
Plasmodium falciparum methionine aminopeptidase 2 0.0048 0.0209 0.1412
Echinococcus granulosus casein kinase I alpha 0.0067 0.0392 0.0532
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0116 0.0849 0.1439
Loa Loa (eye worm) hypothetical protein 0.0068 0.04 0.0399
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0036 0.0036
Echinococcus granulosus casein kinase I delta 0.0067 0.0392 0.0532
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Echinococcus granulosus tyrosine protein kinase Src42A 0.0099 0.0689 0.0936
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0169 0.1348 0.2329
Echinococcus multilocularis methionyl aminopeptidase 2 0.0048 0.0209 0.0238
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0311 0.0418
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.005 0.0226 0.0225
Giardia lamblia Kinase, NEK 0.0142 0.1099 0.1899
Brugia malayi Probable tyrosine-protein kinase kin-31 0.003 0.0036 0.0036
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Plasmodium falciparum protein kinase, putative 0.003 0.0036 0.013
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis TK family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus activin receptor type 0.0474 0.4231 0.5748
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.11 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0099 0.0689 0.0782
Echinococcus granulosus casein kinase I alpha 0.0067 0.0392 0.0532
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Schistosoma mansoni protein kinase 0.0194 0.1592 0.2159
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0144 0.0143
Entamoeba histolytica tyrosin kinase, putative 0.003 0.0036 0.003
Echinococcus granulosus peroxidasin 0.0042 0.0148 0.0202
Brugia malayi Bromodomain containing protein 0.0038 0.0117 0.0116
Onchocerca volvulus 0.005 0.0233 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.1158 0.1569
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0036 0.0036
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0142 0.1099 0.6783
Onchocerca volvulus 0.0068 0.04 0.0395
Echinococcus multilocularis dual specificity 0.0639 0.5786 0.6567
Onchocerca volvulus 0.0224 0.1875 0.1871
Echinococcus multilocularis tyrosine protein kinase pr2 0.003 0.0036 0.0041
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0067 0.0392 0.0391
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0194 0.1588 0.2721
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.009 0.0118
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0042 0.0151 0.0172
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.2507 0.4333
Echinococcus granulosus plexin a4 0.0039 0.012 0.0163
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.005 0.0226 0.0391
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0446 0.0602
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.0036 0.0041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0148 0.0148
Echinococcus granulosus neuroglian 0.0114 0.0832 0.113
Trichomonas vaginalis AGC family protein kinase 0.0171 0.1367 0.2362
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0116 0.0849 0.1439
Plasmodium vivax protein kinase, putative 0.003 0.0036 0.011
Loa Loa (eye worm) AGC/AKT protein kinase 0.0056 0.0285 0.0284
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.039 0.0443
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0197 0.1617 0.1617
Loa Loa (eye worm) hypothetical protein 0.0089 0.0596 0.0595
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Brugia malayi Protein kinase domain containing protein 0.0216 0.1799 0.1798
Schistosoma mansoni tyrosine kinase 0.0099 0.0689 0.0932
Loa Loa (eye worm) TK/CSK protein kinase 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0849 0.1148
Echinococcus granulosus dual specificity protein kinase clk2 0.0162 0.1288 0.175
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0048 0.0209 0.033
Echinococcus granulosus tyrosine protein kinase Src64B 0.0099 0.0689 0.0936
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0241 0.2031 0.2759
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0058 0.0303 0.0492
Giardia lamblia Kinase, NEK 0.0142 0.1099 0.1899
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0092 0.0623 0.0707
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Echinococcus granulosus casein kinase I alpha 0.0067 0.0392 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0099 0.0689 0.0936
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0062 0.0108
Brugia malayi P38 map kinase family protein 2 0.0169 0.1348 0.1347
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0147 0.1141 0.1551
Schistosoma mansoni protein kinase 0.0042 0.0151 0.0201
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0052 0.0247 0.0246
Loa Loa (eye worm) carboxylesterase 0.0068 0.04 0.0399
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Onchocerca volvulus 0.003 0.0036 0.0031
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0157 0.1234 0.14
Plasmodium falciparum serine/threonine protein kinase, putative 0.0153 0.12 0.8764
Brugia malayi Cytochrome P450 family protein 0.0036 0.0095 0.0094
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0153 0.12 0.163
Loa Loa (eye worm) AGC/NDR protein kinase 0.0052 0.0247 0.0246
Echinococcus multilocularis roundabout 2 0.0045 0.0183 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) gastrulation defective protein 1 0.015 0.1176 0.1175
Plasmodium vivax glycogen synthase kinase 3, putative 0.0134 0.1018 0.6275
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0162 0.1288 0.2201
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0063
Brugia malayi Protein kinase domain containing protein 0.0207 0.1712 0.1711
Loa Loa (eye worm) hypothetical protein 0.0036 0.0092 0.0091
Trichomonas vaginalis STE family protein kinase 0.0194 0.1588 0.2745
Giardia lamblia Kinase, NEK 0.0142 0.1099 0.1899
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0143
Brugia malayi Endoplasmin precursor 0.0032 0.0062 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Brugia malayi hypothetical protein 0.0286 0.2452 0.2452
Leishmania major casein kinase, putative 0.0067 0.0392 0.0677
Schistosoma mansoni protein kinase 0.0232 0.1945 0.2639
Plasmodium falciparum serine/threonine protein kinase KIN 0.005 0.0226 0.1537
Trichomonas vaginalis AGC family protein kinase 0.0153 0.12 0.2074
Entamoeba histolytica chitinase, putative 0.0082 0.0526 0.0879
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0097 0.0673 0.0915
Echinococcus granulosus cyclin dependent kinase 7 0.0112 0.0815 0.1107
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Loa Loa (eye worm) hypothetical protein 0.0093 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0068 0.04 0.0399
Loa Loa (eye worm) TK/RYK protein kinase 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0392 0.0527
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0041 0.0144 0.0164
Brugia malayi Pre-SET motif family protein 0.0197 0.1617 0.1617
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0639 0.5786 1
Schistosoma mansoni tyrosine kinase 0.0067 0.0394 0.053
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0038 0.0118 0.0134
Schistosoma mansoni tyrosine kinase 0.032 0.2777 0.3769
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0324 0.2819 0.4854
Echinococcus granulosus tyrosine protein kinase ABL1 0.0288 0.2479 0.3367
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0207 0.1712 0.1711
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0028 0.0019 0.0033
Echinococcus multilocularis cyclin dependent kinase 0.0073 0.0446 0.0507
Echinococcus granulosus kinase suppressor of Ras 1 0.003 0.0036 0.0049
Entamoeba histolytica cysteine surface protein, putative 0.003 0.0036 0.003
Schistosoma mansoni neuroglian 0.0045 0.0183 0.0244
Onchocerca volvulus 0.0029 0.0035 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0446 0.0602
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0048 0.0209 0.0279
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0171 0.1367 0.2362
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus serine:threonine kinase SAD 1 0.005 0.0226 0.0307
Echinococcus granulosus growth factor receptor bound protein 2 0.0037 0.0109 0.0148
Leishmania major chitinase 0.0082 0.0526 0.0909
Echinococcus granulosus c src tyrosine kinase 0.0065 0.0372 0.0505
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0064 0.0063
Schistosoma mansoni protein kinase 0.0067 0.0392 0.0527
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0129 0.0978 0.0977
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.2507 0.4315
Echinococcus granulosus protein kinase c iota type 0.0069 0.0412 0.0559
Brugia malayi hypothetical protein 0.0068 0.04 0.0399
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.039 0.0674
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0063
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Leishmania major protein kinase, putative 0.0054 0.0262 0.0452
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Brugia malayi PHD-finger family protein 0.0029 0.0031 0.003
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0094 0.0645 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0127 0.0954 0.1295
Schistosoma mansoni lamin 0.0033 0.0064 0.0082
Schistosoma mansoni neuroligin 3 (S09 family) 0.0068 0.04 0.0539
Schistosoma mansoni tyrosine-protein kinase fps85d 0.003 0.0036 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Plasmodium falciparum tyrosine kinase-like protein 0.003 0.0036 0.013
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Plasmodium falciparum protein kinase, putative 0.003 0.0036 0.013
Echinococcus granulosus roundabout 2 0.0134 0.1019 0.1385
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0063
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0288 0.2479 0.2814
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0064 0.0063
Echinococcus granulosus single minded 2 0.0043 0.0167 0.0227
Loa Loa (eye worm) hypothetical protein 0.0068 0.04 0.0399
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.003 0.0036 0.0031
Schistosoma mansoni hypothetical protein 0.0806 0.7362 1
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0167 0.0166
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0545 0.4903 0.4903
Brugia malayi Protein kinase domain containing protein 0.0112 0.0814 0.0813
Onchocerca volvulus 0.003 0.0036 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Brugia malayi intracellular kinase 0.0134 0.1018 0.1017
Echinococcus granulosus mitogen activated protein kinase 11 0.0169 0.1348 0.1831
Echinococcus granulosus natriuretic peptide receptor 1 0.003 0.0036 0.0049
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0116 0.0849 0.1153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Loa Loa (eye worm) hypothetical protein 0.0065 0.0374 0.0374
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0153 0.12 0.1362
Schistosoma mansoni titin 0.0041 0.0144 0.0191
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0183 0.0183
Echinococcus granulosus TGF-beta receptor type-1 0.0106 0.0759 0.1031
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0639 0.5786 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.0169 0.1348 0.153
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus tyrosine protein kinase Blk 0.0084 0.0551 0.0748
Brugia malayi Receptor family ligand binding region containing protein 0.003 0.0036 0.0036
Echinococcus multilocularis mitogen activated protein kinase 14 0.0169 0.1348 0.153
Loa Loa (eye worm) hypothetical protein 0.0211 0.175 0.1749
Schistosoma mansoni nck2/grb4 0.0036 0.0092 0.012
Echinococcus multilocularis carboxylesterase 5A 0.0404 0.3567 0.4048
Echinococcus granulosus serine:threonine protein kinase N2 0.0052 0.0247 0.0336
Schistosoma mansoni tyrosine kinase 0.0067 0.0394 0.053
Plasmodium falciparum calcium-dependent protein kinase 4 0.0067 0.039 0.2753
Echinococcus multilocularis lysine specific demethylase 5A 0.0094 0.0642 0.0729
Giardia lamblia Kinase, NEK 0.003 0.0036 0.0063
Echinococcus granulosus protein kinase 0.0093 0.0632 0.0859
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0073 0.0446 0.0772
Schistosoma mansoni tyrosine kinase 0.0097 0.0673 0.091
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0052 0.0247 0.0281
Schistosoma mansoni vesicular amine transporter 0.0089 0.0592 0.08
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0031 0.0054 0.0073
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0041 0.0144 0.0143
Echinococcus granulosus cyclin dependent kinase 0.0073 0.0446 0.0606
Schistosoma mansoni titin 0.0029 0.0035 0.0042
Echinococcus granulosus MAM 0.0032 0.0063 0.0086
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0169 0.1348 0.2329
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0036 0.0063
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.1349 0.1348
Echinococcus granulosus tyrosine protein kinase HCK 0.0063 0.0354 0.0481
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trichomonas vaginalis CK1 family protein kinase 0.0067 0.0392 0.0677
Schistosoma mansoni tyrosine kinase 0.0067 0.0394 0.053
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.1018 0.1759
Toxoplasma gondii aurora kinase 0.0153 0.12 0.2048
Loa Loa (eye worm) hypothetical protein 0.0068 0.04 0.0399
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0067 0.039 0.053
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Schistosoma mansoni tyrosine kinase 0.0099 0.0689 0.0932
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0183
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0124
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Brugia malayi serine/threonine-protein kinase PAK 7 0.0234 0.1968 0.1967
Giardia lamblia PHD finger protein 15 0.0029 0.0031 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Onchocerca volvulus 0.005 0.0233 0.0228
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.003 0.0036 0.003
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0194 0.1588 0.1588
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0144 0.0143
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0134 0.1018 0.1759
Loa Loa (eye worm) hypothetical protein 0.0129 0.0978 0.0977
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0116 0.0849 0.6156
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma brucei rac serine-threonine kinase, putative 0.0056 0.0285 0.0461
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0247 0.0427
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0104 0.0741 0.1006
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Echinococcus multilocularis casein kinase I alpha 0.0067 0.0392 0.0444
Echinococcus granulosus tyrosine protein kinase Src42A 0.0056 0.0288 0.0391
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.0093 0.0631 0.0631
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0184 0.025
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Loa Loa (eye worm) hypothetical protein 0.0089 0.0592 0.0591
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0067 0.0392 0.0677
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0031 0.0054 0.0061
Loa Loa (eye worm) carboxylesterase 0.0068 0.04 0.0399
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Echinococcus multilocularis protein kinase 0.003 0.0036 0.0041
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine kinase 0.0171 0.1367 0.1853
Schistosoma mansoni nephrin 0.0045 0.0183 0.0244
Trichomonas vaginalis CMGC family protein kinase 0.0639 0.5786 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0187 0.0254
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0058 0.0303 0.0302
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.6251 0.8491
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0134 0.1018 0.1017
Loa Loa (eye worm) SRC-1 0.0099 0.0689 0.0688
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0209 0.173 0.173
Schistosoma mansoni protein kinase 0.0042 0.0151 0.0201
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0099 0.0689 0.0782
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0247 0.0331
Toxoplasma gondii STE kinase 0.003 0.0036 0.003
Loa Loa (eye worm) TK/FAK protein kinase 0.0323 0.2809 0.2809
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.016 0.127 0.1269
Loa Loa (eye worm) TK protein kinase 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0412 0.0555
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0127 0.0959 0.0958
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.003 0.0036 0.0036
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0324 0.2819 0.2818
Echinococcus granulosus activated cdc42 kinase 1 0.022 0.1834 0.2491
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Echinococcus multilocularis kinase suppressor of Ras 1 0.003 0.0036 0.0041
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0067 0.039 0.0644
Schistosoma mansoni tyrosine kinase 0.0179 0.1451 0.1967
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Echinococcus granulosus titin 0.0053 0.026 0.0353
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0028 0.0019 0.0033
Echinococcus multilocularis activin receptor type 0.0474 0.4231 0.4802
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0026 0.0004 0.0005
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.003 0.0036 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0068 0.04 0.0454
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0084 0.0551 0.0625
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.003 0.0036 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0693 0.0936
Brugia malayi Protein kinase domain containing protein 0.0056 0.0285 0.0284
Loa Loa (eye worm) endoplasmin 0.0032 0.0062 0.0061
Toxoplasma gondii histone kinase SNF1, putative 0.005 0.0226 0.0359
Loa Loa (eye worm) hypothetical protein 0.0197 0.1617 0.1616
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Schistosoma mansoni ephrin receptor 0.003 0.0036 0.0045
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0031 0.003
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0091 0.0618 0.0839
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Entamoeba histolytica hypothetical protein 0.0147 0.1141 0.1946
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0041 0.0144 0.0191
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus receptor type guanylyl cyclase 0.003 0.0036 0.0049
Plasmodium falciparum calcium-dependent protein kinase 5 0.0067 0.039 0.2753
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.003 0.0036 0.003
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis tyrosine protein kinase Srms 0.0084 0.0551 0.0625
Schistosoma mansoni heat shock protein 0.0032 0.0062 0.008
Echinococcus multilocularis mitogen activated protein kinase 14 0.0169 0.1348 0.153
Brugia malayi ribosomal protein S6 kinase alpha 3 0.012 0.0892 0.0892
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0126 0.0217
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0324 0.2819 0.4871
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0194 0.1592 0.2163
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.2397 0.2396
Entamoeba histolytica protein kinase, putative 0.0042 0.0151 0.023
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.0036 0.003
Trichomonas vaginalis serine/threonine kinase, putative 0.0171 0.1367 0.2362
Echinococcus multilocularis plexin a4 0.0039 0.012 0.0136
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0171 0.1367 0.1551
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) hypothetical protein 0.0032 0.0063 0.0062
Brugia malayi Immunoglobulin I-set domain containing protein 0.0053 0.026 0.0259
Schistosoma mansoni tyrosine kinase 0.0103 0.0729 0.0985
Entamoeba histolytica hypothetical protein 0.003 0.0036 0.003
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0153 0.12 0.2048
Brugia malayi serine/threonine protein kinase 6 0.0153 0.12 0.1199
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0073 0.0446 0.0741
Echinococcus multilocularis serine:threonine protein kinase N2 0.0052 0.0247 0.0281
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0058 0.0303 0.0407
Brugia malayi probable protein kinase 0.0151 0.1179 0.1178
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Trypanosoma brucei protein kinase, putative 0.0054 0.0262 0.0421
Entamoeba histolytica casein kinase 1, putative 0.0067 0.0392 0.0646
Echinococcus granulosus para nitrobenzyl esterase 0.0068 0.04 0.0544
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.0036 0.0049
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Echinococcus granulosus epidermal growth factor receptor 0.0097 0.0673 0.0915
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0134 0.1018 0.1379
Loa Loa (eye worm) hypothetical protein 0.03 0.2593 0.2593
Echinococcus granulosus serine:threonine protein kinase NLK 0.0171 0.1367 0.1857
Brugia malayi hypothetical protein 0.0058 0.0303 0.0302
Giardia lamblia Kinase, CMGC GSK 0.0134 0.1018 0.1759
Echinococcus multilocularis death associated protein kinase 1 0.0959 0.8811 1
Trichomonas vaginalis AGC family protein kinase 0.0171 0.1367 0.2362
Schistosoma mansoni tyrosine kinase 0.0065 0.0372 0.05
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0324 0.2819 0.4871
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0062 0.0108
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0492 0.4402 0.4402
Schistosoma mansoni hypothetical protein 0.0032 0.0063 0.0081
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0162 0.1288 0.2227
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.039 0.0525
Plasmodium falciparum tyrosine kinase-like protein 0.003 0.0036 0.013
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0067 0.039 0.2331
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0028 0.0019 0.0033
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.003 0.0036 0.0063
Trichomonas vaginalis CK1 family protein kinase 0.0067 0.0392 0.0677
Onchocerca volvulus Putative endochitinase 0.0082 0.0526 0.0521
Echinococcus granulosus dual specificity 0.0639 0.5786 0.786
Plasmodium vivax hypothetical protein, conserved 0.0129 0.0978 0.6023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0184 0.0245
Echinococcus multilocularis c src tyrosine kinase 0.0065 0.0372 0.0422
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Loa Loa (eye worm) hypothetical protein 0.0058 0.0303 0.0302
Loa Loa (eye worm) chitinase I 0.0082 0.0526 0.0525
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Loa Loa (eye worm) hypothetical protein 0.0058 0.0303 0.0302
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0216 0.1799 0.1798
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0183 0.0183
Toxoplasma gondii hypothetical protein 0.0129 0.0978 0.1663
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0058 0.0303 0.0407
Schistosoma mansoni hypothetical protein 0.0147 0.1141 0.1546
Brugia malayi casein kinase I 0.0067 0.0392 0.0391
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Entamoeba histolytica tyrosin kinase, putative 0.003 0.0036 0.003
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.1018 0.1732
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.0038 0.0114 0.0165
Echinococcus granulosus tyrosine protein kinase shark 0.005 0.0233 0.0317
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0138 0.0157
Entamoeba histolytica receptor protein kinase, putative 0.003 0.0036 0.003
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Trypanosoma cruzi casein kinase, putative 0.0067 0.0392 0.0677
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0262 0.0421
Entamoeba histolytica hypothetical protein 0.003 0.0036 0.003
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.1288 0.2227
Plasmodium falciparum calcium-dependent protein kinase 1 0.0067 0.039 0.2753
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0226 0.0302
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0035 0.0034
Schistosoma mansoni protein kinase 0.003 0.0036 0.0045
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Schistosoma mansoni tyrosine kinase 0.0205 0.1695 0.2298
Brugia malayi Protein kinase domain containing protein 0.0323 0.2809 0.2809
Echinococcus multilocularis epidermal growth factor receptor 0.0097 0.0673 0.0764
Onchocerca volvulus 0.0068 0.04 0.0395
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.009 0.0123
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.003 0.0036 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0199 0.1632 0.2821
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0054 0.0262 0.0452
Brugia malayi heat shock protein 90 0.0032 0.0062 0.0061
Brugia malayi Protein kinase domain containing protein 0.022 0.1834 0.1833
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Brugia malayi Fibronectin type III domain containing protein 0.0093 0.0631 0.0631
Trichomonas vaginalis STE family protein kinase 0.0042 0.0151 0.0262
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0207 0.1712 0.1943
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0404 0.3567 0.4843
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0054 0.0262 0.0452
Echinococcus granulosus epidermal growth factor receptor 0.0097 0.0673 0.0915
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0184 0.0245
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.0036 0.003
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0028 0.0019 0.0033
Brugia malayi hypothetical protein 0.003 0.0036 0.0036
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0041 0.0146 0.0145
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Brugia malayi Protein kinase domain containing protein 0.0179 0.1451 0.145
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0187 0.0212
Schistosoma mansoni tyrosine kinase 0.0065 0.0372 0.05
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Echinococcus granulosus heat shock protein 0.0032 0.0062 0.0085
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0052 0.0247 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.047 0.0634
Brugia malayi GSG2 0.0806 0.7362 0.7361
Brugia malayi Bromodomain containing protein 0.0075 0.0462 0.0461
Leishmania major protein kinase, putative 0.0028 0.0019 0.0033
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Loa Loa (eye worm) AUR protein kinase 0.0153 0.12 0.1199
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0045 0.0178 0.0277
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0157 0.1234 0.1233
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.1288 0.1746
Plasmodium falciparum glycogen synthase kinase 3 0.0134 0.1018 0.7413
Echinococcus granulosus tyrosine kinase 0.0084 0.0551 0.0748
Entamoeba histolytica hypothetical protein 0.003 0.0036 0.003
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0112 0.0815 0.0814
Onchocerca volvulus 0.005 0.0233 0.0228
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Brugia malayi Protein kinase domain containing protein 0.005 0.0233 0.0232
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.016 0.127 0.1725
Brugia malayi Guanylyl cyclase protein 23 0.003 0.0036 0.0036
Echinococcus multilocularis transfer RNA-Thr 0.022 0.1834 0.2082
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.1402 0.19
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0062 0.0108
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Echinococcus multilocularis cyclin dependent kinase 7 0.0112 0.0815 0.0925
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.039 0.0443
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0058 0.0303 0.0523
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0289 0.2486 0.2822
Brugia malayi protein kinase C3,putative 0.0041 0.0146 0.0145
Echinococcus multilocularis growth factor receptor bound protein 2 0.0036 0.0092 0.0104
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Schistosoma mansoni ephrin receptor 0.0034 0.0076 0.0098
Entamoeba histolytica hypothetical protein 0.003 0.0042 0.0039
Echinococcus multilocularis hypothetical protein 0.0147 0.1141 0.1296
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0121 0.012
Plasmodium vivax serine/threonine kinase-1, putative 0.0162 0.1288 0.7973
Onchocerca volvulus 0.0041 0.0142 0.0137
Echinococcus granulosus cyclin dependent kinase 9 0.0076 0.047 0.0639
Echinococcus granulosus cyclin dependent kinase 19 0.0174 0.1402 0.1904
Entamoeba histolytica protein kinase, putative 0.0056 0.0285 0.0461
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0412 0.0555
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0068 0.04 0.3638
Echinococcus granulosus N chimaerin 0.0038 0.0118 0.016
Loa Loa (eye worm) hypothetical protein 0.0404 0.3567 0.3566
Brugia malayi casein kinase 1, delta 0.0067 0.0392 0.0391
Schistosoma mansoni plexin 0.003 0.0043 0.0053
Echinococcus multilocularis tyrosine protein kinase Abl 0.0156 0.123 0.1396
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0068 0.04 0.0399
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2452 0.2783
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis raf serine:threonine protein kinase 0.0047 0.0201 0.0228
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0162 0.1288 0.2201
Echinococcus granulosus cyclin dependent kinase 9 0.0222 0.1855 0.252
Toxoplasma gondii casein kinase I 0.0067 0.0392 0.0646
Onchocerca volvulus 0.0134 0.1018 0.1014
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0069 0.0412 0.0467
Echinococcus multilocularis N chimaerin 0.0038 0.0118 0.0134
Plasmodium falciparum NIMA related kinase 1 0.0142 0.1099 0.8013
Echinococcus granulosus jumonji domain containing protein 0.004 0.0138 0.0188
Echinococcus granulosus tyrosine protein kinase Fps85D 0.005 0.0233 0.0317
Brugia malayi Protein kinase domain containing protein 0.0052 0.0247 0.0246
Brugia malayi Stress-activated protein kinase jnk-1 0.0289 0.2486 0.2486
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.005 0.0233 0.0265
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0129 0.0978 0.1328
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0148 0.1158 0.1314
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.0036 0.0049
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0134 0.1018 0.1732
Onchocerca volvulus 0.0053 0.026 0.0255
Brugia malayi Cell division protein kinase 2 0.0171 0.1367 0.1366
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0116 0.0849 0.1467
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0112 0.0814 0.0813
Loa Loa (eye worm) hypothetical protein 0.0092 0.0621 0.062
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0036 0.0036
Trypanosoma brucei Pseudokinase, putative 0.003 0.0036 0.003
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Schistosoma mansoni protein kinase 0.0151 0.1179 0.1597
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0094 0.0645 0.0644
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0036 0.0036
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0067 0.0392 0.0391
Leishmania major hypothetical protein, conserved 0.003 0.0036 0.0063
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0183 0.0208
Echinococcus granulosus tyrosine protein kinase Lyn 0.0123 0.0914 0.1242
Brugia malayi Cam kinase protein 1 0.0067 0.039 0.0389
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0036 0.0036
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0849 0.0963
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0095 0.0094
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Onchocerca volvulus 0.0058 0.0306 0.0301
Trichomonas vaginalis CMGC family protein kinase 0.0639 0.5786 1
Echinococcus multilocularis tyrosine protein kinase otk 0.0041 0.0144 0.0164
Giardia lamblia Kinase, CAMK CAMKL 0.0171 0.1367 0.2362
Echinococcus granulosus cyclin dependent kinase 1 0.0073 0.0446 0.0606
Entamoeba histolytica protein kinase, putative 0.0046 0.0189 0.0294
Onchocerca volvulus 0.0033 0.0064 0.0059
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.0036 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0187 0.0212
Giardia lamblia Kinase, STE STE20 0.0042 0.0151 0.0262
Echinococcus granulosus TGF beta receptor type 1 0.0106 0.0759 0.1031
Echinococcus multilocularis serine:threonine protein kinase N2 0.0052 0.0247 0.0281
Schistosoma mansoni serine/threonine RGC 0.003 0.0036 0.0045
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.003 0.0036 0.0049
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0052 0.0247 0.0336
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.003 0.0036 0.0041
Loa Loa (eye worm) hypothetical protein 0.0177 0.1424 0.1423
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0187 0.0249
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.003 0.0036 0.0063
Loa Loa (eye worm) TK protein kinase 0.003 0.0036 0.0036
Brugia malayi Variant SH3 domain containing protein 0.0038 0.0118 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus granulosus dual specificity 0.0324 0.2819 0.3829
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Entamoeba histolytica tyrosin kinase, putative 0.0038 0.0114 0.0165
Brugia malayi Carboxylesterase family protein 0.0068 0.04 0.0399
Schistosoma mansoni protein kinase 0.003 0.0036 0.0045
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0323 0.0322
Echinococcus granulosus serine:threonine protein kinase haspin 0.0806 0.7362 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0067 0.0066
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0062 0.0108
Echinococcus multilocularis lachesin 0.0041 0.0144 0.0164
Brugia malayi Protein kinase domain containing protein 0.005 0.0233 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0116 0.0849 0.1439
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Echinococcus granulosus tyrosine protein kinase Fyn 0.0099 0.0689 0.0936
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Echinococcus multilocularis FL cytokine receptor 0.003 0.0036 0.0041
Entamoeba histolytica hypothetical protein 0.003 0.0036 0.003
Schistosoma mansoni growth factor receptor-bound protein 0.0037 0.0109 0.0143
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0062 0.0075
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0183 0.0208
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Entamoeba histolytica SH2-protein kinase domain containing protein 0.005 0.0233 0.0371
Trypanosoma cruzi cdc2-related kinase 1 0.0073 0.0446 0.0772
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0073 0.0446 0.0446
Echinococcus multilocularis tyrosine protein kinase shark 0.005 0.0233 0.0265
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.003 0.0036 0.0049
Echinococcus multilocularis neuroglian 0.0045 0.0183 0.0208
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0196 0.1611 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0143 0.111 0.1508
Schistosoma mansoni protein kinase 0.003 0.0036 0.0045
Leishmania major methionine aminopeptidase 2, putative 0.0048 0.0209 0.0362
Onchocerca volvulus 0.0358 0.3138 0.3134
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0134 0.1018 0.1759
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis tyrosine protein kinase 0.003 0.0036 0.0041
Loa Loa (eye worm) protein kinase domain-containing protein 0.003 0.0036 0.0036
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.0019 0.0033
Echinococcus granulosus heat shock protein 90 0.0032 0.0062 0.0085
Echinococcus multilocularis hemicentin 1 0.0041 0.0144 0.0164
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0289 0.2486 0.2486
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Schistosoma mansoni gliotactin 0.0068 0.04 0.0539
Loa Loa (eye worm) hypothetical protein 0.0129 0.0978 0.0977
Schistosoma mansoni cell adhesion molecule 0.0029 0.0035 0.0042
Echinococcus multilocularis lamin dm0 0.0033 0.0064 0.0072
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0639 0.5786 0.5786
Entamoeba histolytica protein kinase domain containing protein 0.0076 0.047 0.0783
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0028 0.0019 0.0033
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0171 0.1367 0.2362
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.003 0.0036 0.0045
Trypanosoma cruzi Protein kinase B 0.0028 0.0019 0.0033
Brugia malayi integrin-linked kinase 0.003 0.0036 0.0036
Plasmodium falciparum heat shock protein 90 0.0032 0.0062 0.0322
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0144 0.0143
Brugia malayi putative serine/threonine kinase SADA gamma 0.005 0.0226 0.0225
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0062 0.0108
Echinococcus granulosus BC026374 protein S09 family 0.0068 0.04 0.0544
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0036 0.0036
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0143
Brugia malayi Variant SH3 domain containing protein 0.0036 0.0092 0.0091
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.005 0.0226 0.0359
Schistosoma mansoni cell adhesion molecule 0.0041 0.0144 0.0191
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi hypothetical protein 0.0806 0.7362 0.7361
Loa Loa (eye worm) hypothetical protein 0.0103 0.0729 0.0728
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.003 0.0036 0.0031
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0171 0.1367 0.2337
Leishmania major protein kinase A catalytic subunit isoform 2 0.0116 0.0849 0.1467
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0023 0.0008
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.0019 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Entamoeba histolytica protein kinase , putative 0.0153 0.12 0.2048
Brugia malayi jmjC domain containing protein 0.0154 0.1209 0.1208
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Echinococcus granulosus hypothetical protein 0.0138 0.1063 0.1444
Echinococcus granulosus twitchin 0.0138 0.1057 0.1436
Loa Loa (eye worm) hypothetical protein 0.0104 0.0741 0.074
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) hypothetical protein 0.0032 0.0063 0.0062
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.003 0.0036 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0096 0.066 0.0892
Brugia malayi Carboxylesterase family protein 0.0068 0.04 0.0399
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.003 0.0036 0.0049
Schistosoma mansoni cell adhesion molecule 0.0045 0.0183 0.0244
Entamoeba histolytica PH domain containing protein kinase, putative 0.012 0.0886 0.1503
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0157 0.1234 0.1233
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0082 0.0528 0.0717
Loa Loa (eye worm) IKK protein kinase 0.1085 1 1
Loa Loa (eye worm) projectin 0.0029 0.0035 0.0034
Schistosoma mansoni hypothetical protein 0.0029 0.0035 0.0042
Echinococcus multilocularis dual specificity 0.0324 0.2819 0.3199
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0099 0.0689 0.0936
Trypanosoma cruzi casein kinase, putative 0.0067 0.0392 0.0677
Trichomonas vaginalis STE family protein kinase 0.0042 0.0151 0.0262
Brugia malayi C-terminal src kinase protein 1 0.003 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0037
Trichomonas vaginalis protein kinase atmrk1, putative 0.0171 0.1367 0.2362
Echinococcus multilocularis titin 0.0053 0.026 0.0295
Echinococcus granulosus NCK adaptor protein 0.0036 0.0092 0.0125
Trichomonas vaginalis AGC family protein kinase 0.0171 0.1367 0.2362
Schistosoma mansoni hypothetical protein 0.0129 0.0978 0.1324
Echinococcus granulosus neuroglian 0.0045 0.0183 0.0249
Brugia malayi Protein kinase domain containing protein 0.0171 0.1367 0.1366
Loa Loa (eye worm) hypothetical protein 0.005 0.0226 0.0225
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0067 0.039 0.2331
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0099 0.0689 0.0782
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.1367 0.2362
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0148 0.1158 0.1573
Schistosoma mansoni protein kinase 0.0054 0.0262 0.0351
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0043 0.0166 0.0287
Trichomonas vaginalis AGC family protein kinase 0.003 0.0036 0.0063
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0031 0.0021
Brugia malayi Protein kinase domain containing protein 0.0052 0.0247 0.0246
Trichomonas vaginalis AGC family protein kinase 0.0153 0.12 0.2074
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.12 0.1626
Onchocerca volvulus 0.003 0.0036 0.0031
Plasmodium falciparum conserved protein, unknown function 0.0129 0.0978 0.7116
Entamoeba histolytica casein kinase, putative 0.0067 0.0392 0.0646
Schistosoma mansoni tyrosine kinase 0.0048 0.0206 0.0275
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0089 0.0592 0.08
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0247 0.0427
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0036 0.0092 0.0091
Echinococcus granulosus Protein kinase C brain isozyme 0.0069 0.0412 0.0559
Trichomonas vaginalis STE family protein kinase 0.0194 0.1588 0.2745
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1799 0.244
Entamoeba histolytica protein kinase, putative 0.0324 0.2819 0.4854
Loa Loa (eye worm) TK/EGFR protein kinase 0.0097 0.0673 0.0673
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0345 0.0464
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0143
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.0036 0.0041
Brugia malayi Variant SH3 domain containing protein 0.0036 0.0092 0.0091
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0038 0.0118 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0187 0.0249
Schistosoma mansoni protein kinase 0.0093 0.0632 0.0854
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.005 0.0226 0.0391
Brugia malayi Protein kinase domain containing protein 0.0324 0.2819 0.2818
Brugia malayi cyclin-dependent kinase 7 homolog 0.0259 0.22 0.22
Echinococcus granulosus tyrosine protein kinase Srms 0.005 0.0233 0.0317
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Brugia malayi hypothetical protein 0.0032 0.0063 0.0062
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi serine/threonine kinase 12 0.0153 0.12 0.1199
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0171 0.1367 0.8465
Schistosoma mansoni endoplasmin 0.0032 0.0062 0.008
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Brugia malayi cyclin-dependent kinase 9 0.0076 0.047 0.0469
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0234 0.1968 0.1967
Echinococcus granulosus rho-associated protein kinase 1 0.0191 0.1564 0.2124
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0089 0.0592 0.08
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.003 0.0036 0.0045
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0068 0.04 0.3638
Onchocerca volvulus 0.005 0.0233 0.0228
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Brugia malayi Tyrosine-protein kinase abl-1 0.0156 0.123 0.123
Echinococcus multilocularis acetylcholinesterase 0.0404 0.3567 0.4048
Onchocerca volvulus 0.005 0.0233 0.0228
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0129 0.0978 0.111
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0041 0.0144 0.0143
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Brugia malayi hypothetical protein 0.0241 0.2031 0.203
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Entamoeba histolytica protein kinase, putative 0.0045 0.0178 0.0277
Plasmodium falciparum calcium-dependent protein kinase 2 0.0067 0.039 0.2753
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0171 0.1367 0.1551
Brugia malayi follicle stimulating hormone receptor 0.028 0.2397 0.2396
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.003 0.004 0.0037
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Onchocerca volvulus 0.0129 0.0978 0.0973
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0035 0.0034
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0207 0.1712 0.1711
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0042 0.0151 0.0206
Brugia malayi Serine/threonine-protein kinase SULU 0.0241 0.2031 0.203
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) TK protein kinase 0.0063 0.0354 0.0353
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0091 0.0617 0.0616
Trypanosoma brucei Flagellum attachment zone protein 20 0.003 0.0036 0.003
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0507 0.4545 0.6173
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0036 0.0036
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0067 0.039 0.0389
Loa Loa (eye worm) TK/ABL protein kinase 0.0288 0.2479 0.2478
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0162 0.1288 0.2227
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0067 0.039 0.0644
Onchocerca volvulus 0.0068 0.04 0.0395
Echinococcus granulosus ephrin type A receptor 4 A 0.003 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0073 0.0449 0.0448
Onchocerca volvulus 0.0058 0.0303 0.0298
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0029 0.0031 0.0037
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0038 0.0118 0.0155
Schistosoma mansoni protein kinase 0.0106 0.0759 0.1027
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Plasmodium vivax tyrosine kinase-like protein, putative 0.003 0.0036 0.011
Entamoeba histolytica protein kinase, putative 0.0324 0.2819 0.4854
Echinococcus granulosus mitogen activated protein kinase 14 0.0169 0.1348 0.1831
Echinococcus granulosus intermediate filament protein 0.0033 0.0064 0.0087
Loa Loa (eye worm) hypothetical protein 0.0093 0.0631 0.0631
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0167 0.0189
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0011 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Entamoeba histolytica protein kinase, putative 0.0046 0.0189 0.0294
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.003 0.0036 0.0049
Brugia malayi MH2 domain containing protein 0.0119 0.088 0.0879
Schistosoma mansoni tyrosine kinase 0.0143 0.111 0.1503
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0028 0.0019 0.0033
Entamoeba histolytica protein kinase, putative 0.0067 0.039 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0153 0.12 0.2048
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0026 0.0004 0.0004
Echinococcus multilocularis twitchin 0.0049 0.0221 0.0251
Echinococcus granulosus mitogen activated protein kinase 15 0.0171 0.1367 0.1857
Leishmania major protein kinase, putative 0.0067 0.039 0.0674
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0148 0.1158 0.1157
Loa Loa (eye worm) AGC/PKA protein kinase 0.0116 0.0849 0.0848
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0116 0.0849 0.1467
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0035 0.0034
Loa Loa (eye worm) TK protein kinase 0.0084 0.0551 0.055
Loa Loa (eye worm) CAMK protein kinase 0.0053 0.026 0.0259
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.003 0.0036 0.003
Giardia lamblia Kinase, AGC PKA 0.0116 0.0849 0.1467
Echinococcus multilocularis cyclin dependent kinase 9 0.0076 0.047 0.0534
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0134 0.1018 0.1383
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0042 0.0151 0.0206
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0036 0.0036
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0126 0.0217
Echinococcus granulosus NDR protein kinase 0.0052 0.0247 0.0336
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0194 0.1588 0.2745
Giardia lamblia Kinase, NEK 0.003 0.0036 0.0063
Plasmodium falciparum protein serine/threonine kinase-1 0.0162 0.1288 0.9419
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0031 0.0021
Echinococcus granulosus integrin linked protein kinase 0.003 0.0036 0.0049
Loa Loa (eye worm) TK protein kinase 0.003 0.0036 0.0036
Giardia lamblia Methionine aminopeptidase 0.0048 0.0209 0.0362
Echinococcus multilocularis NCK adaptor protein 0.0037 0.0109 0.0124
Loa Loa (eye worm) hypothetical protein 0.0286 0.2452 0.2452
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0065 0.0372 0.05
Trichomonas vaginalis STE family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis protein kinase shaggy 0.0134 0.1018 0.1155
Schistosoma mansoni protein kinase 0.0209 0.173 0.2347
Onchocerca volvulus 0.003 0.0043 0.0038
Plasmodium vivax SET domain protein, putative 0.0028 0.0023 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis hemicentin 1 0.0041 0.0144 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Plasmodium vivax endoplasmin, putative 0.0032 0.0062 0.0273
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0153 0.12 0.7418
Entamoeba histolytica protein kinase, putative 0.0153 0.12 0.2048
Loa Loa (eye worm) AUR protein kinase 0.0153 0.12 0.1199
Echinococcus multilocularis tyrosine kinase 0.003 0.0036 0.0041
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0209 0.0362
Brugia malayi protein-tyrosine kinase 0.0084 0.0551 0.055
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0143
Echinococcus multilocularis microtubule associated serine:threonine protein 0.0026 0.0004 0.0004
Echinococcus granulosus slit 2 protein 0.0033 0.0067 0.0091
Schistosoma mansoni hypothetical protein 0.0058 0.0306 0.0411
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0639 0.5786 1
Loa Loa (eye worm) TK protein kinase 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0849 0.1148
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Brugia malayi SH2 domain containing protein 0.005 0.0233 0.0232
Echinococcus granulosus c-Jun N-terminal kinases 0.0289 0.2486 0.3377
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0169 0.1348 0.2329
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0143 0.111 0.126
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.016 0.127 0.1269
Loa Loa (eye worm) TK protein kinase 0.003 0.0036 0.0036
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0048 0.0209 0.0362
Echinococcus multilocularis protein kinase 0.003 0.0036 0.0041
Loa Loa (eye worm) plexin A 0.0039 0.012 0.0119
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0127 0.0959 0.0958
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0116 0.0849 0.0848
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.2507 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0054 0.0262 0.0421
Echinococcus multilocularis protein kinase c epsilon type 0.0069 0.0412 0.0467
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Entamoeba histolytica serine/threonine protein kinase, putative 0.005 0.0226 0.0359
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.04 0.0539
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0187 0.0249
Echinococcus multilocularis BC026374 protein (S09 family) 0.0068 0.04 0.0454
Echinococcus multilocularis calcium dependent protein kinase 0.0043 0.0165 0.0187
Brugia malayi ephrin receptor 1 precursor 0.003 0.0036 0.0036
Echinococcus granulosus casein kinase i 0.0067 0.0392 0.0532
Echinococcus multilocularis cyclin dependent kinase 1 0.0073 0.0446 0.0507
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.0068 0.04 0.0399
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.0639 0.5786 1
Trichomonas vaginalis STE family protein kinase 0.0042 0.0151 0.0262
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0207 0.1712 0.1711
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0159 0.1259 0.1258
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) TK protein kinase 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0815 0.1103
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0041 0.0144 0.0139
Plasmodium vivax casein kinase 1, putative 0.0067 0.0392 0.234
Echinococcus granulosus tyrosine kinase 0.003 0.0036 0.0049
Schistosoma mansoni roundabout 0.0041 0.0144 0.0191
Trichomonas vaginalis CMGC family protein kinase 0.0639 0.5786 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0045 0.0183 0.0208
Schistosoma mansoni hypothetical protein 0.003 0.0036 0.0045
Echinococcus granulosus activated cdc42 kinase 1 0.022 0.1834 0.2491
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0158 0.0157
Trichomonas vaginalis serine-threonine protein kinase, putative 0.003 0.0036 0.0063
Loa Loa (eye worm) TK/ACK protein kinase 0.003 0.0036 0.0036
Plasmodium vivax calcium-dependent protein kinase, putative 0.0067 0.039 0.2331
Echinococcus multilocularis insulin receptor 0.0179 0.1451 0.1647
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0036 0.0045
Echinococcus granulosus roundabout 2 0.0045 0.0183 0.0249
Brugia malayi Probable tyrosine-protein kinase kin-31 0.003 0.0036 0.0036
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0174 0.1402 0.1401
Schistosoma mansoni nephrin 0.0118 0.0871 0.1178
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Toxoplasma gondii AGC kinase 0.0116 0.0849 0.1439
Entamoeba histolytica hypothetical protein 0.0324 0.2819 0.4854
Entamoeba histolytica hypothetical protein 0.003 0.0036 0.003
Brugia malayi endochitinase 0.0091 0.0619 0.0618
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0806 0.7362 0.8355
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.0036 0.0041
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0849 0.0963
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0039 0.0126 0.0217
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Echinococcus multilocularis PAK box P21 Rho binding 0.0042 0.0151 0.0172
Onchocerca volvulus 0.003 0.0036 0.0031
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0116 0.0849 0.1467
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0063
Echinococcus granulosus lachesin 0.0041 0.0144 0.0196
Schistosoma mansoni cell adhesion molecule 0.0108 0.078 0.1055
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0031 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0053 0.026 0.0259
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.003
Trichomonas vaginalis AGC family protein kinase 0.0142 0.1099 0.1899
Giardia lamblia Kinase, CMGC GSK 0.0134 0.1018 0.1759
Brugia malayi Protein kinase domain containing protein 0.005 0.0233 0.0232
Brugia malayi hypothetical protein 0.005 0.0233 0.0232
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.0117
Schistosoma mansoni tyrosine kinase 0.0268 0.2282 0.3097
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0073 0.0446 0.0446
Giardia lamblia Kinase, STE STE20 0.0194 0.1588 0.2745
Toxoplasma gondii AGC kinase 0.0116 0.0849 0.1439
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0062 0.0075
Echinococcus granulosus casein kinase I delta 0.0067 0.0392 0.0532
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0058 0.0303 0.0344
Schistosoma mansoni hypothetical protein 0.0032 0.0063 0.0081
Brugia malayi Sex muscle abnormal protein 5 0.0036 0.0092 0.0091
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0241 0.2031 0.203
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Brugia malayi Carboxylesterase family protein 0.0404 0.3567 0.3566
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0067 0.039 0.0644
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.1712 0.2322
Onchocerca volvulus Putative endochitinase 0.0091 0.0619 0.0614
Schistosoma mansoni survival motor neuron protein 0.0058 0.0306 0.0411
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0121 0.0159
Echinococcus multilocularis dual specificity protein kinase clk2 0.0162 0.1288 0.1462
Brugia malayi Protein kinase domain containing protein 0.0174 0.1402 0.1401
Loa Loa (eye worm) hypothetical protein 0.0049 0.0221 0.022
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0318 0.0361
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0039 0.0126 0.0217
Echinococcus multilocularis heat shock protein 0.0032 0.0062 0.0071
Plasmodium falciparum calcium-dependent protein kinase 3 0.0067 0.039 0.2753
Onchocerca volvulus 0.0043 0.0166 0.0161
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis 0.0093 0.0632 0.0718
Schistosoma mansoni vam6/vps39 related 0.0058 0.0303 0.0407
Echinococcus granulosus titin 0.0053 0.026 0.0353
Schistosoma mansoni atypical protein kinase C 0.0069 0.0412 0.0555
Brugia malayi Plexin repeat family protein 0.003 0.0043 0.0042
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0035 0.0034
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.1018 0.1732
Echinococcus multilocularis cyclin dependent kinase 1 0.0073 0.0446 0.0507
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0099 0.0693 0.0941
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0116 0.0849 0.1153
Schistosoma mansoni tyrosine protein kinase 0.003 0.0036 0.0045
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.11 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.039 0.053
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Trichomonas vaginalis protein tyrosine kinase, putative 0.003 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.0032 0.0063 0.0062
Echinococcus multilocularis serine threonine protein kinase 0.0052 0.0247 0.0281
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Loa Loa (eye worm) TK/Met protein kinase 0.003 0.0036 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Entamoeba histolytica protein kinase domain containing protein 0.0324 0.2819 0.4854
Giardia lamblia Kinase, AGC AKT 0.012 0.0892 0.1542
Echinococcus granulosus methionyl aminopeptidase 2 0.0048 0.0209 0.0284
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.016 0.127 0.1441
Entamoeba histolytica receptor protein kinase, putative 0.003 0.0036 0.003
Trichomonas vaginalis AGC family protein kinase 0.0153 0.12 0.2074
Schistosoma mansoni protein kinase 0.0042 0.0151 0.0201
Leishmania major protein kinase A catalytic subunit 0.0116 0.0849 0.1467
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0849 0.1467
Echinococcus multilocularis casein kinase i 0.0067 0.0392 0.0444
Echinococcus granulosus calcium dependent protein kinase 0.0043 0.0165 0.0224
Echinococcus granulosus hemicentin 1 0.0041 0.0144 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0289 0.2486 0.3374
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Echinococcus granulosus tyrosine protein kinase Fyn 0.0099 0.0689 0.0936
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0058 0.0303 0.0523
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0184 0.149 0.2024
Brugia malayi bone morphogenetic protein type 1 receptor 0.0112 0.0814 0.0813
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0209 0.173 0.1964
Loa Loa (eye worm) jmjC domain-containing protein 0.0096 0.066 0.0659
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0183 0.0183
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0036 0.0092 0.0091
Entamoeba histolytica protein kinase, putative 0.0063 0.0354 0.0581
Echinococcus multilocularis lamin 0.0033 0.0064 0.0072
Onchocerca volvulus 0.0028 0.0023 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Echinococcus multilocularis neuroligin 0.0068 0.04 0.0454
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Schistosoma mansoni protein kinase 0.003 0.0036 0.0045
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0806 0.7362 0.8355
Schistosoma mansoni protein kinase 0.0171 0.1367 0.1853
Echinococcus granulosus protein kinase C gamma type 0.0052 0.0247 0.0336
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Onchocerca volvulus 0.1085 1 1
Echinococcus multilocularis musashi 0.0033 0.0064 0.0072
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.003 0.0036 0.0036
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0095 0.0128
Leishmania major protein kinase, putative 0.0162 0.1288 0.2227
Brugia malayi Protein kinase domain containing protein 0.0545 0.4903 0.4903
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0103 0.0729 0.099
Entamoeba histolytica PH domain containing protein kinase, putative 0.012 0.0886 0.1503
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0093 0.0632 0.0632
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.04 0.0539
Loa Loa (eye worm) hypothetical protein 0.0068 0.04 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0693 0.0936
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0232 0.1945 0.2208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0492 0.4402 0.4402
Trichomonas vaginalis AGC family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.0026 0.0004 0.0003
Echinococcus granulosus cyclin dependent kinase 5 0.0073 0.0446 0.0606
Schistosoma mansoni myosin-binding protein-related 0.0029 0.0035 0.0042
Brugia malayi cell division control protein 2 homolog 0.0073 0.0446 0.0446
Brugia malayi Raf kinase 0.003 0.0036 0.0036
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis MAM 0.0032 0.0063 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0116 0.0849 0.1467
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.1288 0.1746
Loa Loa (eye worm) TK/EPH protein kinase 0.003 0.0036 0.0036
Trypanosoma brucei aurora B kinase 0.0153 0.12 0.2048
Brugia malayi Protein kinase domain containing protein 0.005 0.0233 0.0232
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0092 0.0623 0.0847
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0307 0.0306
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0089 0.0592 0.0672
Loa Loa (eye worm) TK protein kinase 0.0169 0.1349 0.1348
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0058 0.0303 0.0411
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0094 0.0645 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus multilocularis dual specificity 0.0639 0.5786 0.6567
Echinococcus multilocularis peroxidasin 0.0042 0.0148 0.0168
Echinococcus multilocularis epidermal growth factor receptor 0.0097 0.0673 0.0764
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0048 0.0209 0.033
Toxoplasma gondii AGC kinase 0.0052 0.0247 0.0396
Schistosoma mansoni src-type protein tyrosine kinase-related 0.003 0.0036 0.0045
Onchocerca volvulus 0.003 0.0036 0.0031
Echinococcus granulosus dual specificity 0.0639 0.5786 0.786
Loa Loa (eye worm) hypothetical protein 0.0029 0.0035 0.0034
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.003 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.007 0.0419 0.0419
Loa Loa (eye worm) hypothetical protein 0.0029 0.0035 0.0034
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.1373 0.1861
Trypanosoma cruzi protein kinase, putative 0.003 0.0036 0.0063
Schistosoma mansoni vav2 0.0042 0.0155 0.0206
Brugia malayi Peroxidasin 0.0042 0.0148 0.0148
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.0019 0.0021
Brugia malayi Pre-SET motif family protein 0.0028 0.0023 0.0022
Brugia malayi Carboxylesterase family protein 0.0068 0.04 0.0399
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0162 0.1288 0.2201
Echinococcus multilocularis serine:threonine protein kinase 38 0.0052 0.0247 0.0281
Echinococcus multilocularis ephrin type A receptor 4 A 0.003 0.0036 0.0041
Brugia malayi protein unc-22 0.0053 0.026 0.0259
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0169 0.1348 0.2304
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Echinococcus granulosus carboxylesterase 5A 0.0404 0.3567 0.4845
Loa Loa (eye worm) hypothetical protein 0.007 0.0419 0.0418
Loa Loa (eye worm) hypothetical protein 0.0404 0.3567 0.3566
Brugia malayi protein C17H12.11 0.007 0.0419 0.0419
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0171 0.1373 0.1372
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Onchocerca volvulus Putative endochitinase 0.0091 0.0619 0.0614
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0171 0.1367 0.2362
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.0036 0.003
Schistosoma mansoni tyrosine kinase 0.0097 0.0673 0.091
Schistosoma mansoni adapter molecule crk 0.0036 0.0092 0.012
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0062 0.0075
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0069 0.0409 0.0408
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Echinococcus granulosus dual specificity mitogen activated protein 0.0194 0.1588 0.2157
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.2507 0.4315
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0084 0.0551 0.0748
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Echinococcus granulosus Immunoglobulin 0.0089 0.0592 0.0804
Plasmodium falciparum casein kinase 1 0.0067 0.0392 0.2764
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0446 0.0772
Entamoeba histolytica hypothetical protein 0.0035 0.009 0.0124
Entamoeba histolytica hypothetical protein 0.003 0.0036 0.003
Echinococcus multilocularis casein kinase I delta 0.0067 0.0392 0.0444
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma cruzi cdc2-related kinase 3 0.0073 0.0446 0.0772
Plasmodium falciparum protein kinase 5 0.0073 0.0446 0.3172
Trichomonas vaginalis AGC family protein kinase 0.0171 0.1367 0.2362
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0073 0.0446 0.0446
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.009 0.0102
Loa Loa (eye worm) AUR protein kinase 0.0153 0.12 0.1199
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0067 0.039 0.0389
Trypanosoma brucei heat shock protein, putative 0.0032 0.0062 0.0075
Echinococcus multilocularis protein KINase family member (kin 25) 0.0103 0.0729 0.0827
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Onchocerca volvulus 0.003 0.0036 0.0031
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0067 0.039 0.2331
Onchocerca volvulus 0.0067 0.0392 0.0387
Onchocerca volvulus 0.0043 0.0167 0.0162
Schistosoma mansoni bromodomain containing protein 0.0063 0.0352 0.0473
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0276 0.0313
Brugia malayi Prion-like- 0.0041 0.0144 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.1367 0.1853
Brugia malayi Bromodomain containing protein 0.0031 0.0053 0.0052
Leishmania major protein kinase A catalytic subunit isoform 1 0.0116 0.0849 0.1467
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0099 0.0689 0.0782
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0446 0.0772
Schistosoma mansoni serine/threonine protein kinase 0.016 0.127 0.1721
Echinococcus multilocularis tyrosine protein kinase Blk 0.0084 0.0551 0.0625
Entamoeba histolytica ankyrin repeat protein 0.003 0.0036 0.003
Echinococcus granulosus Vam6:Vps39 protein 0.0058 0.0303 0.0411
Echinococcus multilocularis serine:threonine kinase SAD 1 0.005 0.0226 0.0257
Entamoeba histolytica protein kinase domain containing protein 0.0153 0.12 0.2048
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0241 0.2031 0.2305
Giardia lamblia Kinase, CMGC CLK 0.0162 0.1288 0.2227
Entamoeba histolytica protein kinase, putative 0.0056 0.0285 0.0461
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Schistosoma mansoni BC026374 protein (S09 family) 0.0068 0.04 0.0539
Trypanosoma brucei cdc2-related kinase 3 0.0073 0.0446 0.0741
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0162 0.1288 0.2227
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0035 0.0034
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0045 0.0183 0.0208
Trichomonas vaginalis STE family protein kinase 0.0042 0.0151 0.0262
Giardia lamblia Kinase, CAMK CAMKL 0.0196 0.1611 0.2785
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0063
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0849 0.0963
Echinococcus multilocularis integrin linked protein kinase 0.003 0.0036 0.0041
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0187 0.0186
Echinococcus multilocularis casein kinase I delta 0.0067 0.0392 0.0444
Leishmania major protein kinase, putative 0.0039 0.0126 0.0217
Schistosoma mansoni septate junction protein 0.0041 0.0144 0.0191
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0639 0.5786 1
Trypanosoma cruzi casein kinase, putative 0.0067 0.0392 0.0677
Loa Loa (eye worm) TK/FER protein kinase 0.005 0.0233 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0285 0.0492
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0042 0.0151 0.0206
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0099 0.0689 0.0782
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0095 0.0107
Schistosoma mansoni titin 0.0053 0.026 0.0349
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.0036 0.0041
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Schistosoma mansoni lipoxygenase 0.0055 0.0276 0.037
Brugia malayi Protein kinase domain containing protein 0.0073 0.0446 0.0446
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0091 0.0617 0.07
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0062 0.0075
Onchocerca volvulus Alhambra homolog 0.0029 0.0031 0.0026
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0029 0.0035 0.0047
Trichomonas vaginalis STE family protein kinase 0.0042 0.0151 0.0262
Brugia malayi Protein kinase domain containing protein 0.0091 0.0617 0.0616
Echinococcus multilocularis tyrosine protein kinase HCK 0.0063 0.0354 0.0402
Echinococcus granulosus roundabout 2 0.0045 0.0183 0.0249
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0067 0.039 0.0389
Brugia malayi PAS domain containing protein 0.0059 0.0311 0.031
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0209 0.173 0.235
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0037
Onchocerca volvulus 0.0129 0.0978 0.0973
Plasmodium vivax methionine aminopeptidase 2, putative 0.0048 0.0209 0.1196
Echinococcus multilocularis natriuretic peptide receptor 1 0.003 0.0036 0.0041
Brugia malayi Hr1 repeat family protein 0.0052 0.0247 0.0246
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Onchocerca volvulus 0.003 0.0036 0.0031
Brugia malayi p70 ribosomal S6 kinase beta 0.0052 0.0247 0.0246
Toxoplasma gondii protein kinase domain-containing protein 0.003 0.0036 0.003
Echinococcus multilocularis mitogen activated protein kinase 11 0.0169 0.1348 0.153
Schistosoma mansoni septate junction protein 0.0041 0.0144 0.0191
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0037
Echinococcus granulosus protein tyrosine kinase 0.032 0.2777 0.3772
Echinococcus multilocularis cyclin dependent kinase 5 0.0073 0.0446 0.0507
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0207 0.1712 0.2326
Leishmania major heat shock protein 83-1 0.0032 0.0062 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0849 0.1148
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Loa Loa (eye worm) hypothetical protein 0.0159 0.1259 0.1258
Brugia malayi Protein kinase domain containing protein 0.003 0.0036 0.0036
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0036 0.0092 0.012
Leishmania major protein kinase, putative 0.0162 0.1288 0.2227
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.003 0.0036 0.0036
Onchocerca volvulus 0.0168 0.1338 0.1334
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0121 0.0137
Onchocerca volvulus 0.0037 0.0102 0.0097
Brugia malayi hypothetical protein 0.007 0.0419 0.0419
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Loa Loa (eye worm) TK/KIN6 protein kinase 0.003 0.0036 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Trichomonas vaginalis CK1 family protein kinase 0.0067 0.0392 0.0677
Loa Loa (eye worm) TK/ROR protein kinase 0.0055 0.0276 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.1367 0.2362
Entamoeba histolytica hypothetical protein 0.003 0.0036 0.003
Brugia malayi hypothetical protein 0.003 0.0036 0.0036
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0052 0.0247 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Loa Loa (eye worm) hypothetical protein 0.0557 0.5016 0.5016
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0639 0.5786 0.7859
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0154 0.1209 0.1642
Schistosoma mansoni lamin 0.0033 0.0064 0.0082
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.1564 0.212
Echinococcus granulosus defective proboscis extension response 0.0089 0.0592 0.0804
Trypanosoma cruzi cdc2-related kinase 1 0.0073 0.0446 0.0772
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.003 0.0036 0.0036
Brugia malayi Protein kinase domain 0.0042 0.0151 0.0151
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Schistosoma mansoni rap gtpase-activating protein 0.0058 0.0303 0.0407
Entamoeba histolytica protein kinase, putative 0.0042 0.0151 0.023
Loa Loa (eye worm) TK/ALK protein kinase 0.0619 0.5603 0.5602
Onchocerca volvulus 0.0068 0.04 0.0395
Echinococcus granulosus fibroblast growth factor receptor 4 0.0143 0.111 0.1508
Brugia malayi Protein kinase domain containing protein 0.0619 0.5605 0.5604
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0209 0.0362
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0099 0.0689 0.0782
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.003 0.0036 0.0041
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0056 0.0288 0.0327
Schistosoma mansoni tyrosine kinase 0.003 0.0036 0.0045
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0142 0.1099 0.1873
Trichomonas vaginalis STE family protein kinase 0.0194 0.1588 0.2745
Giardia lamblia Kinase 0.003 0.0036 0.0063
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0171 0.1367 0.1857
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0226 0.0391
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.0036 0.0049
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0169 0.1348 0.1347
Echinococcus multilocularis heat shock protein 70 0.003 0.0036 0.0041
Onchocerca volvulus 0.003 0.0036 0.0031
Onchocerca volvulus 0.0159 0.1259 0.1255
Loa Loa (eye worm) hypothetical protein 0.0116 0.0849 0.0848
Loa Loa (eye worm) hypothetical protein 0.0127 0.0954 0.0953
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0019 0.0033
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0062 0.0108
Loa Loa (eye worm) hypothetical protein 0.0121 0.0895 0.0894
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0171 0.1367 0.1366
Brugia malayi jmjC domain containing protein 0.0096 0.066 0.0659
Entamoeba histolytica p21-activated kinase 0.0046 0.0189 0.0294
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Trypanosoma cruzi NIMA-related kinase, putative 0.0028 0.0019 0.0033
Entamoeba histolytica protein kinase, putative 0.0134 0.1018 0.1732
Schistosoma mansoni growth factor receptor-bound protein 0.0036 0.0092 0.012
Trypanosoma brucei protein kinase, putative 0.0134 0.1018 0.1732
Loa Loa (eye worm) hypothetical protein 0.022 0.1834 0.1833
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0116 0.0849 0.1439
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0121 0.0159
Echinococcus granulosus insulin receptor 0.0179 0.1451 0.1971
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.039 0.053
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0157 0.1234 0.1676
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0035 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0226 0.0302
Trichomonas vaginalis set domain proteins, putative 0.0224 0.1875 0.324
Trypanosoma brucei protein kinase, putative 0.0171 0.1367 0.2337
Entamoeba histolytica protein kinase, putative 0.0052 0.0247 0.0396
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0073 0.0446 0.0772
Echinococcus granulosus serine/threonine protein kinase 0.0028 0.0019 0.0026
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.0036 0.003
Schistosoma mansoni serine/threonine kinase 0.0052 0.0247 0.0331
Leishmania major protein kinase, putative 0.0028 0.0019 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0815 0.1103
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0124 0.093 0.1607
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0062 0.0061
Trichomonas vaginalis TKL family protein kinase 0.003 0.0036 0.0063
Giardia lamblia Kinase, CAMK CAMKL 0.0196 0.1611 0.2785
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0042 0.0151 0.0172
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0154 0.1209 0.1372
Trichomonas vaginalis AGC family protein kinase 0.0153 0.12 0.2074
Toxoplasma gondii protein kinase 0.003 0.0036 0.003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0144 0.0143
Schistosoma mansoni endoplasmin 0.0032 0.0062 0.008
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.0232
Entamoeba histolytica protein kinase, putative 0.003 0.0036 0.003
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0048 0.0209 0.0362
Schistosoma mansoni jumonji/arid domain-containing protein 0.0096 0.066 0.0892
Echinococcus multilocularis dual specificity 0.0639 0.5786 0.6567
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0324 0.2819 0.4871
Brugia malayi C1-like domain containing protein 0.0112 0.0809 0.0808
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.2031 0.2755
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0011 0.0012
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0157 0.1234 0.1233
Schistosoma mansoni jumonji domain containing protein 0.0134 0.1024 0.1387
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0028 0.0019 0.0033
Brugia malayi protein kinase C II. 0.0069 0.0412 0.0411
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.2507 0.4333
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.11 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0068 0.04 0.3638
Loa Loa (eye worm) hypothetical protein 0.0073 0.0449 0.0448
Mycobacterium ulcerans chitinase/cellulase 0.007 0.0413 0.3749
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.003 0.0036 0.0036
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.039 0.0443
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0045 0.0183 0.0244
Leishmania major protein kinase, putative 0.003 0.0036 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0247 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0063
Plasmodium vivax protein kinase Crk2 0.0073 0.0446 0.2685
Entamoeba histolytica protein kinase, putative 0.0052 0.0247 0.0396
Trichomonas vaginalis protein kinase atn1, putative 0.003 0.0036 0.0063
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0171 0.1367 0.2362
Echinococcus granulosus microtubule associated protein 2 0.0688 0.6251 0.8492
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0028 0.0022 0.0038
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.003 0.0036 0.0049
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0184 0.149 0.1691
Entamoeba histolytica tyrosine kinase, putative 0.003 0.0036 0.003
Echinococcus multilocularis cyclin dependent kinase 19 0.0174 0.1402 0.1591
Echinococcus granulosus dual specificity 0.0639 0.5786 0.786
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0036 0.003
Brugia malayi hypothetical protein 0.0035 0.009 0.0089

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 2.511886432 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 5.011872336 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 19.95262315 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 25.11886432 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Agonists for Hypoxia Response Element Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 915 ] ChEMBL. No reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 914 ] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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