Detailed information for compound 1333710

Basic information

Technical information
  • TDR Targets ID: 1333710
  • Name: 2-[[5-(naphthalen-1-yloxymethyl)-4-phenyl-1,2 ,4-triazol-3-yl]sulfanyl]acetonitrile
  • MW: 372.443 | Formula: C21H16N4OS
  • H donors: 0 H acceptors: 3 LogP: 4.47 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CCSc1nnc(n1c1ccccc1)COc1cccc2c1cccc2
  • InChi: 1S/C21H16N4OS/c22-13-14-27-21-24-23-20(25(21)17-9-2-1-3-10-17)15-26-19-12-6-8-16-7-4-5-11-18(16)19/h1-12H,14-15H2
  • InChiKey: NXCRCCSZOFDYQR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[5-(1-naphthyloxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetonitrile
  • 2-[[5-(1-naphthyloxymethyl)-4-phenyl-1,2,4-triazol-3-yl]thio]acetonitrile
  • 2-[[5-(naphthalen-1-yloxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]ethanenitrile
  • BAS 02053717
  • ZINC04093252
  • SMR000010985
  • [5-(Naphthalen-1-yloxymethyl)-4-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl]-acetonitrile
  • MLS000032064

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Bacillus anthracis Anthrax lethal factor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis calcium binding protein, putative 0.0024 0.0146 0.0299
Leishmania major hypothetical protein, conserved 0.0024 0.0151 0.032
Echinococcus granulosus potassium large conductance calcium activated 0.0017 0.0069 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Brugia malayi cathepsin B-like cysteine proteinase 0.0705 0.7893 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.011 0.113 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Giardia lamblia Cathepsin B precursor 0.0244 0.2647 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0662 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0024 0.0151 0.0105
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0071 0.009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0297 0.0377
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0072 0.0092
Echinococcus multilocularis calcium uptake protein 1 0.0024 0.0151 0.0151
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0412 0.4564 1
Leishmania major centrin, putative,caltractin, putative 0.0024 0.0146 0.0299
Onchocerca volvulus 0.011 0.113 0.4379
Trypanosoma brucei caltractin, putative 0.0024 0.0146 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Entamoeba histolytica cysteine protease, putative 0.0037 0.0297 0.154
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0744 0.0942
Brugia malayi Cathepsin L-like precursor 0.0081 0.0793 0.1004
Leishmania major calmodulin-like protein 0.0024 0.0146 0.0299
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Toxoplasma gondii cathepsin B 0.0244 0.2647 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0043 0.0367 0.0381
Loa Loa (eye worm) papain family cysteine protease containing protein 0.003 0.0211 0.0268
Brugia malayi Cathepsin L-like precursor 0.011 0.113 0.1432
Trichomonas vaginalis calmodulin, putative 0.0024 0.0151 0.032
Schistosoma mansoni mitochondrial solute carrier 0.0024 0.0146 0.0184
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.3122 0.3955
Echinococcus granulosus cathepsin L cysteine proteinase 0.011 0.113 0.1432
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0412 0.4564 0.5745
Toxoplasma gondii hypothetical protein 0.0043 0.0367 0.1157
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.011 0.113 0.4118
Leishmania major programmed cell death 6 protein-like protein 0.0024 0.0146 0.0299
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0037 0.0297 0.0586
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.1847
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0678 0.7583 0.7583
Brugia malayi hypothetical protein 0.0017 0.0069 0.0087
Onchocerca volvulus 0.011 0.113 0.4379
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0058
Schistosoma mansoni centrin 0.0024 0.0146 0.0184
Trypanosoma brucei mitochondrial calcium uptake 1 0.0024 0.0146 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0037 0.0297 0.0887
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0017 0.0069 0.0087
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0037 0.0297 0.0377
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0053 0.0053
Plasmodium vivax centrin-1, putative 0.0024 0.0146 0.0385
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0091 0.0115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0297 0.0887
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0024 0.0146 0.0184
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0024 0.0146 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0037 0.0297 0.0887
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0144 0.1514 0.1847
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0017 0.0069 0.0087
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Echinococcus granulosus hyperpolarization activated cyclic 0.0017 0.0069 0.0087
Loa Loa (eye worm) fibroinase 0.011 0.113 0.1432
Loa Loa (eye worm) voltage-gated potassium channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0058
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0069 0.0087
Echinococcus multilocularis cathepsin L cysteine protease 0.011 0.113 0.113
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0144 0.1514 0.1847
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0297 0.0377
Entamoeba histolytica cysteine proteinase, putative 0.0067 0.0635 0.497
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.009
Plasmodium vivax serine-repeat antigen (SERA) 0.0037 0.0297 0.1451
Loa Loa (eye worm) hypothetical protein 0.0125 0.1293 0.1639
Echinococcus granulosus cathepsin L cysteine protease 0.0067 0.0635 0.0804
Brugia malayi programmed cell death protein 6 0.0024 0.0146 0.0184
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0043 0.0367 0.0664
Leishmania major centrin, putative 0.0024 0.0146 0.0299
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0151 0.0423
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0609 0.0771
Plasmodium falciparum serine repeat antigen 6 0.0037 0.0297 0.1986
Echinococcus granulosus two pore calcium channel protein 1 0.0017 0.0069 0.0087
Brugia malayi EF hand family protein 0.0024 0.0151 0.0191
Echinococcus granulosus calpain 0.0144 0.1514 0.1918
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0091 0.0087
Trypanosoma cruzi cysteine protease, putative 0.0067 0.0635 0.0724
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.1669 0.2114
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Schistosoma mansoni voltage-dependent calcium channel 0.0017 0.0069 0.0087
Trypanosoma brucei Calpain-like protein 1.1 0.0043 0.0367 0.0664
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0229 0.0291
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0069 0.0087
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0069 0.0087
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0017 0.0069 0.0087
Trypanosoma brucei calpain, putative 0.0043 0.0367 0.0664
Echinococcus multilocularis tumor protein p63 0.0408 0.4515 0.4515
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0069 0.0069
Giardia lamblia Cathepsin B precursor 0.0037 0.0297 0.0586
Giardia lamblia Cathepsin L precursor 0.0037 0.0297 0.0586
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Brugia malayi cathepsin L-like cysteine proteinase 0.0037 0.0297 0.0377
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Toxoplasma gondii transporter, cation channel family protein 0.0142 0.1488 0.5506
Plasmodium falciparum serine repeat antigen 5 0.0037 0.0297 0.1986
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0705 0.7893 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Schistosoma mansoni lamin 0.0033 0.0244 0.0309
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0037 0.0297 0.1451
Echinococcus multilocularis sodium channel protein 0.0288 0.3144 0.3144
Plasmodium falciparum serine repeat antigen 8 0.0037 0.0297 0.1986
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0037 0.0297 0.0377
Loa Loa (eye worm) hypothetical protein 0.003 0.0211 0.0268
Echinococcus granulosus tachykinin peptides receptor 99D 0.0588 0.6562 0.8314
Trypanosoma cruzi cruzipain precursor, putative 0.011 0.113 0.1357
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0125 0.1293 0.1639
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Echinococcus multilocularis cysteine protease 0.011 0.113 0.113
Schistosoma mansoni calmodulin 0.0024 0.0146 0.0184
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Trichomonas vaginalis calcineurin B subunit, putative 0.0024 0.0151 0.032
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0069 0.0069
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0037 0.0297 0.1451
Plasmodium vivax vivapain-1 0.0067 0.0635 0.3824
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0662 0.5
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0705 0.7893 1
Loa Loa (eye worm) hypothetical protein 0.0228 0.2462 0.3119
Echinococcus multilocularis ryanodine receptor 44f 0.0017 0.0069 0.0069
Schistosoma mansoni cathepsin C 0.0037 0.0297 0.0377
Schistosoma mansoni neuronal calcium sensor 0.0024 0.0146 0.0184
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0017 0.0069 0.0087
Brugia malayi Cathepsin L-like cysteine proteinase 0.0081 0.0793 0.1004
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0297 0.0887
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0662 0.5
Echinococcus granulosus programmed cell death protein 0.0024 0.0146 0.0184
Giardia lamblia Cathepsin L precursor 0.0037 0.0297 0.0586
Toxoplasma gondii calmodulin CAM1 0.0024 0.0151 0.032
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0037 0.0297 0.1451
Echinococcus granulosus calumenin 0.0024 0.0151 0.0191
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0502 0.0502
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Echinococcus granulosus neuronal calcium sensor 0.0024 0.0146 0.0184
Trypanosoma cruzi caltractin, putative 0.0024 0.0146 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0238 0.2581 0.327
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0244 0.0309
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0069 0.0087
Plasmodium falciparum cysteine proteinase falcipain 2a 0.011 0.113 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0662 0.0838
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.113 0.1357
Echinococcus granulosus intermediate filament protein 0.0033 0.0244 0.0309
Plasmodium vivax vivapain-2 0.011 0.113 0.7305
Brugia malayi voltage-dependent calcium channel 0.0017 0.0069 0.0087
Schistosoma mansoni calmodulin related calcium binding protein 0.0024 0.0146 0.0184
Echinococcus granulosus cathepsin l1 0.011 0.113 0.1432
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0635 0.2197
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.113 0.1357
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0037 0.0297 0.1451
Echinococcus multilocularis two pore calcium channel protein 1 0.0017 0.0069 0.0069
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0793 0.2808
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0184
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Leishmania major centrin, putative 0.0024 0.0146 0.0299
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Trypanosoma cruzi cruzipain precursor, putative 0.003 0.0211 0.0183
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0358 0.0828
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0043 0.0367 0.0381
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0043 0.0367 0.1157
Entamoeba histolytica grainin, putative 0.0024 0.0151 0.0054
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0017 0.0069 0.0087
Loa Loa (eye worm) ion channel NompC 0.0017 0.0069 0.0087
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0071 0.009
Brugia malayi Transient-receptor-potential like protein 0.0017 0.0069 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0297 0.0887
Echinococcus granulosus shaker cognate 0.0017 0.0069 0.0087
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0678 0.7583 0.7583
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0024 0.0146 0.0172
Giardia lamblia Cysteine protease 0.0037 0.0297 0.0586
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Brugia malayi cathepsin L-like precursor 0.0081 0.0793 0.1004
Echinococcus granulosus calpain 7 C02 family 0.0144 0.1514 0.1918
Giardia lamblia Cathepsin B precursor 0.0037 0.0297 0.0586
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0024 0.0146 0.0099
Toxoplasma gondii calcium-dependent protein kinase 0.0024 0.0151 0.032
Loa Loa (eye worm) hypothetical protein 0.0705 0.7893 1
Plasmodium falciparum serine repeat antigen 2 0.0037 0.0297 0.1986
Trypanosoma brucei calpain, putative 0.0043 0.0367 0.0664
Loa Loa (eye worm) hypothetical protein 0.0339 0.3728 0.4723
Echinococcus multilocularis musashi 0.0033 0.0244 0.0244
Echinococcus granulosus tumor protein p63 0.0408 0.4515 0.572
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0044 0.0373 0.0678
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0069 0.0087
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0043 0.0367 0.0381
Trypanosoma brucei Calpain-like protein 2 0.0043 0.0367 0.0664
Leishmania major calcineurin B subunit, putative 0.0024 0.0146 0.0299
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0067 0.0635 0.0804
Loa Loa (eye worm) hypothetical protein 0.0037 0.0299 0.0379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0705 0.7893 1
Onchocerca volvulus Cathepsin L homolog 0.011 0.113 0.4379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0297 0.0887
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0664
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0744 0.0942
Trichomonas vaginalis hypothetical protein 0.0043 0.0367 0.1157
Echinococcus multilocularis dnaJ subfamily B 0.0445 0.494 0.494
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0402 0.1292
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0069 0.0087
Giardia lamblia Cathepsin B precursor 0.0037 0.0297 0.0586
Plasmodium falciparum serine repeat antigen 7 0.0037 0.0297 0.1986
Echinococcus granulosus sodium channel protein 0.0017 0.0069 0.0087
Plasmodium falciparum cysteine proteinase falcipain 1 0.0067 0.0635 0.5235
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0043 0.0367 0.1157
Plasmodium falciparum cysteine proteinase falcipain 2b 0.011 0.113 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0297 0.0377
Echinococcus granulosus cathepsin b 0.0705 0.7893 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0043 0.0367 0.1157
Brugia malayi cation channel family protein 0.0017 0.0069 0.0087
Schistosoma mansoni peptidylglycine monooxygenase 0.0121 0.1248 0.1582
Entamoeba histolytica cysteine protease, putative 0.011 0.113 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0367 0.0465
Loa Loa (eye worm) voltage-dependent calcium channel 0.0142 0.1488 0.1885
Echinococcus granulosus lamin 0.0033 0.0244 0.0309
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0043 0.0367 0.1157
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0069 0.0265
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0017 0.0069 0.0087
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0043 0.0367 0.0381
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0297 0.0887
Schistosoma mansoni two-pore calcium channel 0.0017 0.0069 0.0087
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0297 0.0377
Echinococcus multilocularis cathepsin l cysteine peptidase 0.011 0.113 0.113
Giardia lamblia Cysteine protease 0.0037 0.0297 0.0586
Echinococcus granulosus cathepsin b 0.0705 0.7893 1
Trypanosoma brucei Calpain-like protein 1.2 0.0043 0.0367 0.0664
Giardia lamblia Cathepsin B precursor 0.0037 0.0297 0.0586
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0081 0.0793 0.0925
Schistosoma mansoni neuronal calcium sensor 0.0024 0.0146 0.0184
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0069 0.0069
Onchocerca volvulus 0.0081 0.0793 0.307
Echinococcus multilocularis calbindin 32 0.0024 0.0151 0.0151
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0299 0.0379
Entamoeba histolytica cysteine protease, putative 0.0037 0.0297 0.154
Plasmodium falciparum serine repeat antigen 4 0.0037 0.0297 0.1986
Giardia lamblia Cathepsin B precursor 0.0244 0.2647 1
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0069 0.0087
Brugia malayi cathepsin F-like cysteine proteinase 0.003 0.0211 0.0268
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0744 0.0942
Schistosoma mansoni calpain C (C02 family) 0.0144 0.1514 0.1918
Plasmodium vivax calpain, putative 0.0144 0.1514 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0037 0.0297 0.1451
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0069 0.0087
Schistosoma mansoni intermediate filament proteins 0.0033 0.0244 0.0309
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0037 0.0297 0.1451
Brugia malayi calpain 5 0.0043 0.0367 0.0465
Echinococcus granulosus calcium uptake protein 1 0.0024 0.0151 0.0191
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0635 0.0724
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0017 0.0069 0.0087
Echinococcus granulosus EF hand domain containing family member A2 0.0024 0.0146 0.0184
Echinococcus granulosus cathepsin l cysteine peptidase 0.011 0.113 0.1432
Entamoeba histolytica protein kinase, putative 0.0101 0.1021 0.8888
Trypanosoma cruzi centrin, putative 0.0024 0.0146 0.0099
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0017 0.0069 0.0069
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0071 0.009
Brugia malayi fibroinase precursor 0.0037 0.0297 0.0377
Toxoplasma gondii EFHC1, putative 0.0024 0.0146 0.0299
Leishmania major i/6 autoantigen-like protein 0.0024 0.0146 0.0299
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0043 0.0367 0.0381
Trichomonas vaginalis calcium binding protein, putative 0.0024 0.0146 0.0299
Trichomonas vaginalis centrin, putative 0.0024 0.0146 0.0299
Loa Loa (eye worm) hypothetical protein 0.0281 0.3074 0.3895
Loa Loa (eye worm) hypothetical protein 0.0081 0.0793 0.1004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0402 0.0509
Brugia malayi TAR-binding protein 0.0076 0.0744 0.0942
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0297 0.0887
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.3215
Schistosoma mansoni calpain (C02 family) 0.0144 0.1514 0.1918
Echinococcus multilocularis hypothetical protein 0.0144 0.1514 0.1514
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0024 0.0146 0.0099
Loa Loa (eye worm) ctsf protein 0.011 0.113 0.1432
Leishmania major calmodulin, putative 0.0024 0.0146 0.0299
Loa Loa (eye worm) cathepsin B 0.0244 0.2647 0.3353
Trypanosoma cruzi centrin, putative 0.0024 0.0146 0.0099
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0017 0.0069 0.0087
Trypanosoma brucei calpain-like protein, putative 0.0144 0.1514 0.3215
Brugia malayi Cathepsin L-like precursor 0.011 0.113 0.1432
Echinococcus granulosus TRP transient receptor potential channel 0.0017 0.0069 0.0087
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0069 0.0087
Entamoeba histolytica calpain family cysteine protease, putative 0.0043 0.0367 0.2246
Brugia malayi Papain family cysteine protease containing protein 0.011 0.113 0.1432
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0664
Leishmania major cysteine peptidase A (CPA) 0.011 0.113 0.4118
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0297 0.0377
Onchocerca volvulus 0.0037 0.0297 0.1152
Schistosoma mansoni cpg binding protein 0.0033 0.025 0.0316
Schistosoma mansoni cathepsin S (C01 family) 0.0037 0.0297 0.0377
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0244 0.2647 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0091 0.0091
Onchocerca volvulus 0.0058 0.0536 0.2078
Brugia malayi CXXC zinc finger family protein 0.0031 0.0229 0.0291
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0017 0.0069 0.0087
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0091 0.0115
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.1669 0.1669
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0091 0.005
Leishmania major phospholipase c-like protein 0.0024 0.0146 0.0299
Schistosoma mansoni centrin-related 0.0024 0.0146 0.0184
Trichomonas vaginalis calpain, putative 0.0043 0.0367 0.1157
Trypanosoma cruzi calmodulin, putative 0.0024 0.0146 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Trypanosoma brucei calpain-like protein, putative 0.0144 0.1514 0.3215
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0744 0.0942
Plasmodium vivax unspecified product 0.0037 0.0297 0.1451
Leishmania major calmodulin, putative 0.0024 0.0146 0.0299
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) calpain family protein 1 0.0382 0.4221 0.5348
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) calpain 0.0144 0.1514 0.1918
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0069 0.0087
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Echinococcus multilocularis calmodulin 0.0024 0.0146 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0037 0.0297 0.0887
Loa Loa (eye worm) calpain family protein 1 0.0281 0.3074 0.3895
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0588 0.6562 0.6562
Schistosoma mansoni calpain-7 (C02 family) 0.0144 0.1514 0.1918
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0069 0.0069
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0069 0.0069
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Entamoeba histolytica cysteine proteinase 1, putative 0.0067 0.0635 0.497
Echinococcus granulosus calpain A 0.0144 0.1514 0.1918
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0069 0.0069
Echinococcus granulosus dnaJ subfamily B 0.0445 0.494 0.6258
Schistosoma mansoni dopamine-beta-monooxygenase 0.0121 0.1248 0.1582
Echinococcus multilocularis geminin 0.0371 0.4089 0.4089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0635 0.2197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0502 0.0636
Echinococcus granulosus calcium activated potassium channel 0.0017 0.0069 0.0087
Toxoplasma gondii preprocathepsin c precursor, putative 0.0037 0.0297 0.0887
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Brugia malayi Calmodulin-like protein 0.0024 0.0146 0.0184
Onchocerca volvulus 0.0024 0.0146 0.0564
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0744 0.0942
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0069 0.0069
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0017 0.0069 0.0069
Echinococcus multilocularis centrin 2 0.0024 0.0146 0.0146
Schistosoma mansoni cathepsin B (C01 family) 0.0037 0.0297 0.0377
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0678 0.7583 0.9607
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0069 0.0087
Entamoeba histolytica hypothetical protein, conserved 0.0024 0.0151 0.0054
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0032 0.0237 0.0301
Echinococcus multilocularis transfer RNA-Gly 0.0017 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0297 0.0887
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0144 0.1514 0.1847
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0069 0.0087
Echinococcus granulosus EF HAND 1 calcium binding site 0.0024 0.0146 0.0184
Giardia lamblia Cathepsin L precursor 0.0037 0.0297 0.0586
Giardia lamblia Hypothetical protein 0.0037 0.0297 0.0586
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.003 0.0211 0.0268
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0091 0.0087
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Loa Loa (eye worm) calcium channel 0.0678 0.7583 0.9607
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0406 0.4493 0.4493
Toxoplasma gondii hypothetical protein 0.0125 0.1293 0.4751
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0017 0.0069 0.0069
Giardia lamblia Cathepsin L precursor 0.0037 0.0297 0.0586
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Giardia lamblia Cathepsin L-like protease 0.0037 0.0297 0.0586
Entamoeba histolytica cysteine protease, putative 0.0037 0.0297 0.154
Onchocerca volvulus 0.0238 0.2581 1
Echinococcus multilocularis calcium activated potassium channel 0.0017 0.0069 0.0069
Trypanosoma cruzi conserved protein 0.0043 0.0367 0.0381
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0037 0.0297 0.1986
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0069 0.0069
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Brugia malayi calpain 7 0.0144 0.1514 0.1918
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.011 0.113 0.1432
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0024 0.0151 0.0191
Schistosoma mansoni transient receptor potential channel 4 0.0017 0.0069 0.0087
Echinococcus multilocularis voltage dependent calcium channel 0.0678 0.7583 0.7583
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0678 0.7583 0.7583
Entamoeba histolytica cysteine protease, putative 0.0037 0.0297 0.154
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Schistosoma mansoni calpain-2 (C02 family) 0.0043 0.0367 0.0465
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Trypanosoma cruzi calmodulin, putative 0.0024 0.0146 0.0099
Echinococcus multilocularis programmed cell death protein 0.0024 0.0146 0.0146
Echinococcus granulosus calbindin 32 0.0024 0.0151 0.0191
Brugia malayi hypothetical protein 0.0286 0.3122 0.3955
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0067 0.0635 0.0804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Onchocerca volvulus 0.0024 0.0146 0.0564
Trichomonas vaginalis calpain, putative 0.0043 0.0367 0.1157
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0297 0.0377
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0037 0.0297 0.1986
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0043 0.0367 0.0664
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0744 0.0942
Onchocerca volvulus 0.011 0.113 0.4379
Giardia lamblia Cathepsin B precursor 0.0037 0.0297 0.0586
Echinococcus granulosus histone acetyltransferase KAT2B 0.0153 0.1619 0.2051
Trichomonas vaginalis myosin light chain 1, putative 0.0024 0.0146 0.0299
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Toxoplasma gondii centrin, putative 0.0024 0.0146 0.0299
Brugia malayi follicle stimulating hormone receptor 0.0284 0.3108 0.3938
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0037 0.0297 0.1451
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Brugia malayi Papain family cysteine protease containing protein 0.0067 0.0635 0.0804
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0017 0.0069 0.0087
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0536 0.0679
Entamoeba histolytica cysteine proteinase, putative 0.0067 0.0635 0.497
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0037 0.0297 0.1451
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.0069 0.0087
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0496 0.0629
Echinococcus granulosus geminin 0.0371 0.4089 0.518
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0662 0.0838
Trypanosoma brucei calpain-like protein, putative 0.0144 0.1514 0.3215
Schistosoma mansoni ef hand domain family member A2 0.0024 0.0146 0.0184
Echinococcus granulosus two pore calcium channel protein 2 0.0017 0.0069 0.0087
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0091 0.0091
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0024 0.0146 0.0385
Onchocerca volvulus 0.011 0.113 0.4379
Loa Loa (eye worm) hypothetical protein 0.0016 0.0053 0.0067
Loa Loa (eye worm) hypothetical protein 0.0678 0.7583 0.9607
Echinococcus granulosus sodium leak channel non selective protein 0.0017 0.0069 0.0087
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0244 0.2647 0.3295
Onchocerca volvulus Cathepsin L homolog 0.011 0.113 0.4379
Brugia malayi cathepsin Z-like cysteine proteinase 0.0037 0.0297 0.0377
Trypanosoma brucei antigen, putative 0.0144 0.1514 0.3215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Echinococcus granulosus lamin dm0 0.0033 0.0244 0.0309
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.011 0.113 0.4118
Schistosoma mansoni cathepsin s 0.003 0.0211 0.0268
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0037 0.0297 0.0377
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0069 0.0069
Entamoeba histolytica hypothetical protein 0.0037 0.0297 0.154
Schistosoma mansoni hypothetical protein 0.0017 0.0071 0.009
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Echinococcus granulosus cathepsin L 0.0037 0.0297 0.0377
Schistosoma mansoni Mername-AA248 (C02 family) 0.0144 0.1514 0.1918
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0678 0.7583 0.9607
Echinococcus multilocularis potassium large conductance calcium activated 0.0017 0.0069 0.0069
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0228 0.2462 0.3119
Echinococcus granulosus calpain 5 0.0144 0.1514 0.1918
Trypanosoma brucei calpain-like protein, putative 0.0144 0.1514 0.3215
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0496 0.0629
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0091 0.0029
Echinococcus granulosus transient receptor potential gamma protein 0.0017 0.0069 0.0087
Leishmania major hypothetical protein, conserved 0.0024 0.0146 0.0299
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Echinococcus multilocularis lamin dm0 0.0033 0.0244 0.0244
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0377
Echinococcus multilocularis programmed cell death protein 0.0024 0.0146 0.0146
Leishmania major hypothetical protein, unknown function 0.0043 0.0367 0.1157
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0297 0.0887
Trypanosoma brucei kinesin, putative 0.0101 0.1021 0.2118
Brugia malayi calpain family protein 1 0.0382 0.4221 0.5348
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0635 0.126
Echinococcus multilocularis EF hand domain containing family member A2 0.0024 0.0151 0.0151
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0037 0.0297 0.1986
Echinococcus multilocularis hyperpolarization activated cyclic 0.0017 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0382 0.4221 0.5348
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0662 0.0838
Giardia lamblia Cysteine protease 0.0037 0.0297 0.0586
Plasmodium vivax unspecified product 0.0067 0.0635 0.3824
Schistosoma mansoni cpg binding protein 0.0033 0.025 0.0316
Trichomonas vaginalis centrin, putative 0.0024 0.0146 0.0299
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0211 0.0183
Toxoplasma gondii EF hand domain-containing protein 0.0024 0.0146 0.0299
Plasmodium falciparum serine repeat antigen 1 0.0037 0.0297 0.1986
Loa Loa (eye worm) hypothetical protein 0.0142 0.1488 0.1885
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.113 0.1357
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0071 0.009
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0069 0.0087
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0024 0.0146 0.0099
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0705 0.7893 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0017 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0297 0.0887
Schistosoma mansoni calpain-7 (C02 family) 0.0144 0.1514 0.1918
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Schistosoma mansoni neuronal calcium sensor 0.0024 0.0146 0.0184
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Entamoeba histolytica cysteine proteinase, putative 0.0067 0.0635 0.497
Plasmodium falciparum calpain 0.0043 0.0367 0.2655
Echinococcus multilocularis calpain 7 (C02 family) 0.0144 0.1514 0.1514
Entamoeba histolytica calpain large subunit domain III containing protein 0.0101 0.1021 0.8888
Trypanosoma brucei Component of motile flagella 41 0.0024 0.0146 0.0172
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0017 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.5606
Entamoeba histolytica cysteine protease, putative 0.0037 0.0297 0.154
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0037 0.0297 0.0377
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0069 0.0069
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0037 0.0297 0.154
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0043 0.0367 0.0381
Brugia malayi cathepsin F-like cysteine proteinase 0.0037 0.0297 0.0377
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0017 0.0069 0.0087
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.006 0.0551 0.0698
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0297 0.0377
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0017 0.0069 0.0087
Echinococcus multilocularis calpain 0.0144 0.1514 0.1514
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0017 0.0069 0.0087
Schistosoma mansoni hypothetical protein 0.0043 0.0367 0.0465
Plasmodium vivax unspecified product 0.003 0.0211 0.0848
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0744 0.0942
Trypanosoma cruzi major cysteine proteinase, putative 0.0037 0.0297 0.0292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0297 0.0887
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0081 0.0793 0.1004
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0017 0.0069 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Trichomonas vaginalis calcium binding protein, putative 0.0024 0.0146 0.0299
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0377
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Echinococcus granulosus voltage gated hydrogen channel 1 0.0017 0.0069 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0793 0.2808
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0244 0.2647 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0793 0.1004
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0037 0.0297 0.0586
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Trypanosoma brucei Calpain-like protein CALP1.3 0.0043 0.0367 0.0664
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0592 0.2029
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0037 0.0297 0.154
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0297 0.0377
Onchocerca volvulus 0.0024 0.0151 0.0585
Echinococcus multilocularis conserved hypothetical protein 0.0017 0.0069 0.0069
Leishmania major calpain family cysteine protease-like protein 0.0043 0.0367 0.1157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0367 0.1157
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0069 0.0087
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0069 0.0087
Echinococcus granulosus cathepsin L 0.0067 0.0635 0.0804
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0091 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.0211 0.0268
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0069 0.0087
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0017 0.0069 0.0087
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Schistosoma mansoni hypothetical protein 0.0024 0.0146 0.0184
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0744 0.0942
Echinococcus granulosus GPCR family 2 0.0017 0.0071 0.009
Trichomonas vaginalis calmodulin-2, putative 0.0024 0.0146 0.0299
Schistosoma mansoni hypothetical protein 0.0371 0.4089 0.518
Echinococcus multilocularis cysteine protease 0.011 0.113 0.113
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0017 0.0069 0.0069
Loa Loa (eye worm) calmodulin-like protein 0.0024 0.0146 0.0184
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0069 0.0087
Schistosoma mansoni survival motor neuron protein 0.0058 0.0536 0.0679
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0043 0.0367 0.1157
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0496 0.0629
Echinococcus multilocularis cathepsin l cysteine peptidase 0.011 0.113 0.113
Loa Loa (eye worm) RNA binding protein 0.0076 0.0744 0.0942
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0024 0.0146 0.0299
Echinococcus granulosus neurocalcin 0.0024 0.0146 0.0184
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0069 0.0069
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0017 0.0069 0.0087
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0069 0.0087
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Echinococcus multilocularis GPCR, family 2 0.0017 0.0071 0.0071
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0043 0.0367 0.0381
Echinococcus granulosus calmodulin 0.0024 0.0146 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0297 0.0887
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0297 0.0887
Schistosoma mansoni transient receptor potential channel 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0377
Brugia malayi olfactory channel protein osm-9 0.0017 0.0069 0.0087
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0069 0.0087
Trypanosoma brucei centrin, putative 0.0024 0.0146 0.0172
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.5606
Echinococcus multilocularis lamin 0.0033 0.0244 0.0244
Plasmodium falciparum centrin-1 0.0024 0.0146 0.0527
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0662 0.0662
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.1847
Echinococcus granulosus tar DNA binding protein 0.0076 0.0744 0.0942
Plasmodium vivax vivapain-2 0.011 0.113 0.7305
Echinococcus multilocularis EF hand domain containing family member A2 0.0024 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0037 0.0297 0.0887
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0017 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0146 0.0299
Loa Loa (eye worm) calpain D 0.0043 0.0367 0.0465
Echinococcus multilocularis neurocalcin 0.0024 0.0146 0.0146
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0069 0.0069
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0297 0.1152
Loa Loa (eye worm) ryanodine receptor 0.0017 0.0069 0.0087
Trichomonas vaginalis calcium binding proteins, putative 0.0024 0.0146 0.0299
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0228 0.2462 0.3119
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0502 0.0636
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0146 0.0299
Trypanosoma brucei centrin, putative 0.0024 0.0146 0.0172
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0678 0.7583 0.9607
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Toxoplasma gondii cathepsin CPC1 0.0037 0.0297 0.0887
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0377
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.5606
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0043 0.0367 0.1157
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0069 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0553 0.0701
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0037 0.0297 0.1451
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0069 0.0087
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Schistosoma mansoni cathepsin F (C01 family) 0.011 0.113 0.1432
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0297 0.0887
Echinococcus multilocularis neuronal calcium sensor 0.0024 0.0146 0.0146
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0297 0.0377
Schistosoma mansoni hypothetical protein 0.0445 0.494 0.6258
Trypanosoma cruzi centrin-3 0.0024 0.0146 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0502 0.0636
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0377
Brugia malayi calpain 5 0.0101 0.1021 0.1293
Brugia malayi Cathepsin L-like precursor 0.003 0.0211 0.0268
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0069 0.0069
Loa Loa (eye worm) programmed cell death protein 6 0.0024 0.0151 0.0191
Echinococcus granulosus hyperpolarization activated cyclic 0.0017 0.0069 0.0087
Echinococcus multilocularis transient receptor potential gamma protein 0.0017 0.0069 0.0069
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0024 0.0146 0.0184
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Trypanosoma cruzi cysteine proteinase, putative 0.0067 0.0635 0.0724
Brugia malayi Cathepsin L-like precursor 0.011 0.113 0.1432
Echinococcus multilocularis calpain family protein 1, d 0.0281 0.3074 0.3074
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0678 0.7583 0.9607
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0037 0.0297 0.0377
Brugia malayi Cathepsin L-like precursor 0.0081 0.0793 0.1004
Brugia malayi intermediate filament protein 0.0033 0.0244 0.0309
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0678 0.7583 0.7583
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Entamoeba histolytica cysteine proteinase 2 0.0067 0.0635 0.497
Schistosoma mansoni hypothetical protein 0.0017 0.0071 0.009
Schistosoma mansoni transient receptor potential channel 0.0017 0.0069 0.0087
Trypanosoma brucei cysteine peptidase, putative 0.0043 0.0367 0.0664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0635 0.126
Loa Loa (eye worm) hypothetical protein 0.0033 0.0244 0.0309
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.1847
Brugia malayi cathepsin Z-like cysteine proteinase 0.0037 0.0297 0.0377
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0043 0.0367 0.0381
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0662 0.2301
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0069 0.0087
Echinococcus granulosus calpain A 0.0407 0.4498 0.5699
Echinococcus multilocularis calmodulin 0.0024 0.0146 0.0146
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0144 0.1514 0.1847
Giardia lamblia Cathepsin L-like protease 0.0037 0.0297 0.0586
Echinococcus multilocularis cathepsin b 0.0705 0.7893 0.7893
Loa Loa (eye worm) hypothetical protein 0.006 0.0553 0.0701
Loa Loa (eye worm) hypothetical protein 0.003 0.0211 0.0268
Trypanosoma cruzi major cysteine proteinase, putative 0.0037 0.0297 0.0292
Brugia malayi calpain family protein 1 0.0382 0.4221 0.5348
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0402 0.2185
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0071 0.009
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Trypanosoma cruzi calmodulin, putative 0.0024 0.0146 0.0099
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0069 0.0087
Echinococcus granulosus cathepsin l1 0.0081 0.0793 0.1004
Schistosoma mansoni reticulocalbin 0.0024 0.0151 0.0191
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0286 0.3122 0.3955
Schistosoma mansoni hypothetical protein 0.0024 0.0146 0.0184
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0024 0.0146 0.0146
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0069 0.0087
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Echinococcus multilocularis cathepsin L 0.0067 0.0635 0.0635
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.3122 0.3122
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0244 0.0309
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0069 0.0087
Toxoplasma gondii centrin 0.0024 0.0146 0.0299
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Leishmania major protein kinase, putative 0.0024 0.0146 0.0299
Brugia malayi RNA binding protein 0.0076 0.0744 0.0942
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0091 0.005
Schistosoma mansoni neuronal calcium sensor 0.0024 0.0146 0.0184
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0244 0.0309
Onchocerca volvulus 0.0031 0.0229 0.0889
Echinococcus granulosus EF hand domain containing family member A2 0.0024 0.0151 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Entamoeba histolytica cysteine proteinase, putative 0.0067 0.0635 0.497
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0067 0.0635 0.0724
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0793 0.657
Leishmania major calpain protease-like protein 0.0043 0.0367 0.1157
Schistosoma mansoni lamin 0.0033 0.0244 0.0309
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.1669 0.2114
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Trypanosoma brucei hypothetical protein 0.0043 0.0367 0.0664
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0793 0.1004
Brugia malayi cathepsin L precursor 0.0037 0.0297 0.0377
Loa Loa (eye worm) voltage-gated calcium channel 0.0017 0.0069 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0502 0.0636
Toxoplasma gondii troponin c, isotype gamma, putative 0.0024 0.0146 0.0299
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0069 0.0069
Brugia malayi ion channel NompC 0.0017 0.0069 0.0087
Loa Loa (eye worm) acetyltransferase 0.0158 0.1669 0.2114
Trypanosoma brucei I/6 autoantigen 0.0024 0.0146 0.0172
Plasmodium falciparum serine repeat antigen 9 0.0037 0.0297 0.1986
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0043 0.0367 0.1157
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0358 0.2154
Brugia malayi Cathepsin L-like precursor 0.011 0.113 0.1432
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0069 0.0087
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0024 0.0146 0.0172
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0067 0.0635 0.0804
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Trypanosoma cruzi cysteine proteinase, putative 0.0067 0.0635 0.0724
Loa Loa (eye worm) calpain 5 0.0101 0.1021 0.1293
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0069 0.0069
Brugia malayi EF hand family protein 0.0024 0.0146 0.0184
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0037 0.0297 0.1451
Schistosoma mansoni voltage-gated cation channel 0.0678 0.7583 0.9607
Onchocerca volvulus Cathepsin F homolog 0.011 0.113 0.4379
Trichomonas vaginalis calcium binding protein, putative 0.0024 0.0146 0.0299
Schistosoma mansoni calmodulin 0.0024 0.0146 0.0184
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0069 0.0087
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0017 0.0069 0.0069
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0406 0.4493 0.5692
Echinococcus granulosus voltage dependent calcium channel 0.0678 0.7583 0.9607
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0402 0.1292
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0017 0.0069 0.0069
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0382 0.4221 0.5348
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Leishmania major kinesin, putative 0.0101 0.1021 0.3693
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Echinococcus multilocularis sodium leak channel non selective protein 0.0017 0.0069 0.0069
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0017 0.0069 0.0087
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0017 0.0069 0.0087
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.113 0.1357
Schistosoma mansoni reticulocalbin 0.0024 0.0146 0.0184
Echinococcus multilocularis cathepsin b 0.0705 0.7893 0.7893
Toxoplasma gondii cathepsin CPC2 0.0037 0.0297 0.0887
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0017 0.0069 0.0087
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0744 0.0744
Echinococcus granulosus cysteine protease 0.0067 0.0635 0.0804
Giardia lamblia Cathepsin B precursor 0.0244 0.2647 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0037 0.0297 0.0377
Echinococcus multilocularis calumenin 0.0024 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.0017 0.0071 0.009
Schistosoma mansoni hypothetical protein 0.0371 0.4089 0.518
Plasmodium vivax serine-repeat antigen (SERA) 0.0037 0.0297 0.1451
Plasmodium vivax vivapain-3 0.0067 0.0635 0.3824
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0017 0.0069 0.0087
Trypanosoma cruzi I/6 autoantigen, putative 0.0024 0.0146 0.0099
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0017 0.0071 0.009
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0146 0.0172
Echinococcus multilocularis two pore calcium channel protein 2 0.0017 0.0069 0.0069
Loa Loa (eye worm) papain family cysteine protease containing protein 0.011 0.113 0.1432
Schistosoma mansoni hypothetical protein 0.0017 0.0069 0.0087
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0678 0.7583 0.9607
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0069 0.0265
Schistosoma mansoni transient receptor potential channel 0.0017 0.0069 0.0087
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0017 0.0069 0.0087
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0628 0.0796
Giardia lamblia Encystation-specific protease 0.0037 0.0297 0.0586
Trypanosoma cruzi kinesin, putative 0.0101 0.1021 0.1217
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0228 0.2462 0.2462
Giardia lamblia Hypothetical protein 0.0037 0.0297 0.0586
Loa Loa (eye worm) hypothetical protein 0.0121 0.1248 0.1582
Onchocerca volvulus 0.011 0.113 0.4379
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0144 0.1514 0.1847
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.011 0.113 0.4118
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0024 0.0146 0.0099
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0297 0.0887
Giardia lamblia Cathepsin L precursor 0.0037 0.0297 0.0586
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0144 0.1514 0.1847
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0244 0.2647 0.3353
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0017 0.0069 0.0087
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0071 0.0071
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0069 0.0087
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0091 0.0115
Brugia malayi Cyclic-nucleotide gated cation channel 0.0017 0.0069 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Trichomonas vaginalis calmodulin, putative 0.0024 0.0146 0.0299
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0024 0.0146 0.0299
Brugia malayi calpain D 0.0043 0.0367 0.0465
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0502 0.0636
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0043 0.0367 0.0381
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0024 0.0146 0.0099
Trypanosoma brucei protein I/6 0.0024 0.0146 0.0172
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0144 0.1514 0.1847
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0664
Plasmodium falciparum serine repeat antigen 3 0.0037 0.0297 0.1986
Trypanosoma cruzi kinesin, putative 0.0101 0.1021 0.1217
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0091 0.0115
Echinococcus granulosus centrin 2 0.0024 0.0146 0.0184
Echinococcus multilocularis cpg binding protein 0.0033 0.025 0.025
Trypanosoma brucei cysteine peptidase C (CPC) 0.0244 0.2647 0.5735
Echinococcus multilocularis calpain A 0.0407 0.4498 0.4498
Entamoeba histolytica cysteine protease, putative 0.0037 0.0297 0.154
Leishmania major hypothetical protein, conserved 0.0043 0.0367 0.1157
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0144 0.1514 0.3215
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0502 0.0502
Onchocerca volvulus 0.006 0.0553 0.2143
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0402 0.1292
Trichomonas vaginalis calpain, putative 0.0043 0.0367 0.1157
Echinococcus granulosus hypothetical protein 0.0017 0.0069 0.0087
Loa Loa (eye worm) EF hand family protein 0.0024 0.0146 0.0184
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0705 0.7893 1
Trichomonas vaginalis calcineurin B subunit, putative 0.0024 0.0146 0.0299
Toxoplasma gondii cathepsin CPL 0.011 0.113 0.4118
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0017 0.0069 0.0087
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0017 0.0069 0.0087
Giardia lamblia Cysteine protease 0.0037 0.0297 0.0586
Schistosoma mansoni hypothetical protein 0.0037 0.0299 0.0379
Trypanosoma cruzi I/6 autoantigen, putative 0.0024 0.0146 0.0099
Loa Loa (eye worm) cysteine protease 0.011 0.113 0.1432
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0069 0.0087
Schistosoma mansoni rab 0.0024 0.0146 0.0184
Brugia malayi calcium-binding protein 0.0024 0.0146 0.0184
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0284 0.3108 0.3938
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0402 0.1292
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0017 0.0069 0.0087
Echinococcus multilocularis calpain 5 0.0144 0.1514 0.1514
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Brugia malayi Cathepsin L-like precursor 0.011 0.113 0.1432
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0678 0.7583 0.9607
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0061 0.0571 0.0724
Brugia malayi Cathepsin L-like precursor 0.011 0.113 0.1432
Echinococcus multilocularis voltage dependent calcium channel 0.0678 0.7583 0.7583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Echinococcus multilocularis cathepsin L cysteine protease 0.011 0.113 0.113
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0377
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Schistosoma mansoni voltage-gated ion channel 0.0017 0.0069 0.0087
Trypanosoma brucei calmodulin, putative 0.0024 0.0146 0.0172
Echinococcus granulosus ryanodine receptor 44f 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.0055 0.0496 0.0629
Trypanosoma brucei calmodulin, putative 0.0024 0.0151 0.0183
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0053 0.0067
Onchocerca volvulus 0.011 0.113 0.4379
Schistosoma mansoni cathepsin F (C01 family) 0.011 0.113 0.1432
Entamoeba histolytica cysteine protease, putative 0.0067 0.0635 0.497
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0069 0.0087
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Schistosoma mansoni vesicular amine transporter 0.0017 0.0069 0.0087
Onchocerca volvulus 0.0017 0.0069 0.0265
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0358 0.2568
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.1157
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Brugia malayi isocitrate dehydrogenase 0.0019 0.0091 0.0115
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0069 0.0087
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0406 0.4493 0.5692
Leishmania major cathepsin L-like protease 0.011 0.113 0.4118
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0297 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0297 0.0887
Schistosoma mansoni calcium-activated potassium channel 0.0017 0.0069 0.0087
Schistosoma mansoni ryanodine receptor related 0.0017 0.0069 0.0087
Leishmania major calmodulin-like protein 0.0024 0.0146 0.0299
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0406 0.4493 0.5692
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0017 0.0069 0.0087
Onchocerca volvulus 0.011 0.113 0.4379
Echinococcus granulosus voltage dependent calcium channel 0.0142 0.1488 0.1885
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0288 0.3144 0.3983
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Trypanosoma brucei centrin-3 0.0024 0.0146 0.0172
Onchocerca volvulus 0.0033 0.0244 0.0946
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0087
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0017 0.0069 0.0087
Brugia malayi cation channel family protein 0.0017 0.0069 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.113 0.2362
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0043 0.0367 0.0381
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0121 0.1248 0.1582
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0043 0.0367 0.0381
Schistosoma mansoni cpg binding protein 0.0031 0.0229 0.0291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.011 0.113 0.4118
Giardia lamblia Cathepsin L precursor 0.0037 0.0297 0.0586
Loa Loa (eye worm) hypothetical protein 0.011 0.113 0.1432
Echinococcus multilocularis shaker cognate 0.0017 0.0069 0.0069
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0502 0.0636
Entamoeba histolytica cysteine proteinase, putative 0.011 0.113 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0037 0.0297 0.0586
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0072 0.0092
Schistosoma mansoni hypothetical protein 0.0058 0.0536 0.0679
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0091 0.0087
Entamoeba histolytica cysteine proteinase, putative 0.011 0.113 1
Brugia malayi Papain family cysteine protease containing protein 0.0067 0.0635 0.0804
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0228 0.2462 0.3119
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0091 0.0091
Onchocerca volvulus 0.0033 0.0244 0.0946
Echinococcus granulosus cpg binding protein 0.0033 0.025 0.0316
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0069 0.0069
Loa Loa (eye worm) voltage-gated potassium channel 0.0017 0.0069 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0502 0.0636
Echinococcus multilocularis cathepsin L 0.0037 0.0297 0.0297
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0037 0.0297 0.0586

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.9285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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