Detailed information for compound 1338398

Basic information

Technical information
  • TDR Targets ID: 1338398
  • Name: 5-(2-chlorophenyl)-3-methyl-N-[3-(2-oxopropyl )-1,2,4-thiadiazol-5-yl]furan-2-carboxamide
  • MW: 375.829 | Formula: C17H14ClN3O3S
  • H donors: 1 H acceptors: 4 LogP: 3.63 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Cc1nsc(n1)NC(=O)c1oc(cc1C)c1ccccc1Cl
  • InChi: 1S/C17H14ClN3O3S/c1-9-7-13(11-5-3-4-6-12(11)18)24-15(9)16(23)20-17-19-14(21-25-17)8-10(2)22/h3-7H,8H2,1-2H3,(H,19,20,21,23)
  • InChiKey: FCJZQDMSKUNMSK-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • N-(3-acetonyl-1,2,4-thiadiazol-5-yl)-5-(2-chlorophenyl)-3-methyl-furan-2-carboxamide
  • N-(3-acetonyl-1,2,4-thiadiazol-5-yl)-5-(2-chlorophenyl)-3-methyl-2-furancarboxamide
  • N-(3-acetonyl-1,2,4-thiadiazol-5-yl)-5-(2-chlorophenyl)-3-methyl-2-furamide
  • BAS 08209918
  • MLS000707405
  • SMR000288870
  • ZINC03655998

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens karyopherin (importin) beta 1 No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens huntingtin Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Trypsin family protein 0.006 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0069 0.0132 0.0132
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0101 0.0255
Onchocerca volvulus 0.0063 0.0115 0.0272
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.06 0.06
Giardia lamblia Cathepsin L precursor 0.0252 0.0613 0.1743
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0252 0.0613 0.0613
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0053 0.0154
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0252 0.0613 0.0613
Onchocerca volvulus Cathepsin F homolog 0.0878 0.2258 0.5606
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0057 0.0057
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Brugia malayi Cathepsin L-like precursor 0.0878 0.2258 0.2258
Brugia malayi Protein kinase domain containing protein 0.0024 0.0012 0.0012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0041 0.0059 0.0149
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0196 0.0465 0.1179
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.0282 0.0715
Echinococcus multilocularis endothelin converting enzyme 1 0.0091 0.019 0.019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0669 0.0669
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0202 0.0202
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0252 0.0613 0.2559
Trichomonas vaginalis calmodulin, putative 0.015 0.0345 0.0981
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0057 0.0057
Leishmania major hypothetical protein, unknown function 0.0274 0.0669 0.1695
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.093 0.2394 0.2394
Echinococcus multilocularis transmembrane protease serine 3 0.006 0.0107 0.0107
Giardia lamblia Alanyl dipeptidyl peptidase 0.0196 0.0465 0.1323
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0053 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.0465 0.2061
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0252 0.0613 0.2559
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2631 0.6862 0.6862
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0115 0.0115
Toxoplasma gondii prolyl endopeptidase 0.1521 0.3945 1
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0056 0.0056
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0056 0.0158
Brugia malayi cathepsin L-like precursor 0.0625 0.1591 0.1591
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0146 0.0333 0.0333
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0225 0.0641
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0006 0.0039
Leishmania major centrin, putative,caltractin, putative 0.015 0.0345 0.0874
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0057 0.0057
Echinococcus granulosus EF hand domain containing family member A2 0.0153 0.0352 0.0352
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0056 0.0158
Onchocerca volvulus 0.006 0.0107 0.0252
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0091 0.019 0.019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0329 0.0814 0.2062
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0026 0.0026
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0329 0.0814 0.0814
Leishmania major calmodulin-like protein 0.015 0.0345 0.0874
Loa Loa (eye worm) hypothetical protein 0.2207 0.5748 0.5748
Onchocerca volvulus Cathepsin L homolog 0.0252 0.0613 0.1511
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Trypanosoma cruzi cysteine protease, putative 0.0506 0.128 0.128
Onchocerca volvulus 0.0039 0.0053 0.0117
Trichomonas vaginalis calpain, putative 0.0274 0.0669 0.1902
Echinococcus granulosus calpain 0.093 0.2394 0.2394
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.0613 0.1743
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0067 0.0125 0.0317
Brugia malayi prolyl oligopeptidase family protein 0.0329 0.0814 0.0814
Brugia malayi hypothetical protein 0.006 0.0107 0.0107
Brugia malayi cathepsin Z-like cysteine proteinase 0.0252 0.0613 0.0613
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0252 0.0613 0.1743
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1357 0.3516 0.3516
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0053 0.0154
Echinococcus granulosus cathepsin b 0.3826 1 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0053 0.0154
Onchocerca volvulus 0.0146 0.0333 0.0814
Echinococcus multilocularis calpain 0.093 0.2394 0.2394
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0086 0.0176 0.0499
Brugia malayi proteasome subunit beta type 1 0.0067 0.0125 0.0125
Brugia malayi Papain family cysteine protease containing protein 0.0506 0.128 0.128
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0329 0.0814 0.2062
Loa Loa (eye worm) hypothetical protein 0.0356 0.0885 0.0885
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.015 0.0345 0.0345
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0042 0.0105
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0506 0.128 0.5668
Trypanosoma brucei Component of motile flagella 41 0.015 0.0345 0.0874
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0046 0.0071 0.0071
Onchocerca volvulus 0.016 0.037 0.0907
Schistosoma mansoni calmodulin 0.015 0.0345 0.0345
Echinococcus granulosus calbindin 32 0.0153 0.0352 0.0352
Toxoplasma gondii calcium-dependent protein kinase 0.0153 0.0352 0.0892
Trypanosoma cruzi Aph-1 protein, putative 0.0106 0.0228 0.0228
Trypanosoma cruzi 20S proteasome subunit 0.0041 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0057
Leishmania major oligopeptidase b 0.0629 0.1604 0.4065
Schistosoma mansoni neuronal calcium sensor 0.015 0.0345 0.0345
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.015 0.0345 0.1528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Echinococcus multilocularis calpain 5 0.093 0.2394 0.2394
Leishmania major cathepsin L-like protease 0.0978 0.2519 0.6386
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.093 0.2394 0.2394
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0025 0.0025
Loa Loa (eye worm) calpain family protein 1 0.2481 0.6467 0.6467
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Echinococcus granulosus Transglutaminase 0.0035 0.0041 0.0041
Mycobacterium leprae probable zinc metalloprotease 0.0091 0.019 0.1045
Brugia malayi hypothetical protein 0.0133 0.0298 0.0298
Echinococcus granulosus calcium uptake protein 1 0.0153 0.0352 0.0352
Trypanosoma brucei centrin-3 0.0154 0.0355 0.0899
Loa Loa (eye worm) hypothetical protein 0.0252 0.0613 0.0613
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0669 0.1902
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.015 0.0345 0.0345
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0046 0.0071 0.0071
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0225 0.0225
Brugia malayi Cathepsin L-like precursor 0.0878 0.2258 0.2258
Echinococcus multilocularis calpain 7 (C02 family) 0.093 0.2394 0.2394
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.0012 0.0012
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0006 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0006 0.0006
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0252 0.0613 0.2559
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0006 0.0006
Echinococcus multilocularis snurportin 1 0.0372 0.0927 0.0927
Loa Loa (eye worm) hypothetical protein 0.0148 0.0339 0.0339
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Entamoeba histolytica cysteine protease, putative 0.0252 0.0613 0.2714
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0153 0.0352 0.0352
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0434 0.1089 0.1089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.128 0.3243
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0086 0.0176 0.0176
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Onchocerca volvulus 0.015 0.0345 0.0845
Loa Loa (eye worm) hypothetical protein 0.015 0.0345 0.0345
Trypanosoma cruzi calpain cysteine peptidase, putative 0.093 0.2394 0.2394
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0252 0.0613 0.0613
Toxoplasma gondii peptidase family M13 protein 0.0091 0.019 0.0482
Plasmodium falciparum cysteine repeat modular protein 1 0.0024 0.0012 0.0053
Trypanosoma cruzi calmodulin, putative 0.015 0.0345 0.0345
Trypanosoma brucei proteasome beta 6 subunit 0.0067 0.0125 0.0317
Schistosoma mansoni cpg binding protein 0.0029 0.0026 0.0026
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0329 0.0814 0.0814
Trypanosoma cruzi cysteine peptidase, putative 0.0254 0.0617 0.0617
Brugia malayi beta-lactamase family protein 0.0039 0.0053 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0006 0.0006
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.0465 0.2061
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0057 0.0057
Plasmodium falciparum cysteine proteinase falcipain 1 0.0506 0.128 0.5668
Loa Loa (eye worm) hypothetical protein 0.0091 0.019 0.019
Trichomonas vaginalis calcineurin B subunit, putative 0.0153 0.0352 0.1001
Plasmodium falciparum serine repeat antigen 4 0.0252 0.0613 0.2714
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0067 0.0125 0.0555
Trypanosoma cruzi cysteine peptidase, putative 0.0878 0.2258 0.2258
Echinococcus granulosus acylamino acid releasing enzyme 0.0196 0.0465 0.0465
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0057 0.0057
Leishmania major calpain protease-like protein 0.0274 0.0669 0.1695
Giardia lamblia Cathepsin L-like protease 0.0252 0.0613 0.1743
Brugia malayi prolyl oligopeptidase family protein 0.0196 0.0465 0.0465
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Leishmania major phospholipase c-like protein 0.015 0.0345 0.0874
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0878 0.2258 0.2258
Loa Loa (eye worm) hypothetical protein 0.0069 0.0132 0.0132
Giardia lamblia Cathepsin B precursor 0.0252 0.0613 0.1743
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0006 0.0026
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0041 0.0102
Onchocerca volvulus 0.0878 0.2258 0.5606
Plasmodium falciparum serine repeat antigen 5 0.0252 0.0613 0.2714
Onchocerca volvulus 0.0029 0.0025 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Brugia malayi Papain family cysteine protease containing protein 0.0252 0.0613 0.0613
Trypanosoma brucei calpain, putative 0.0274 0.0669 0.1695
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Echinococcus granulosus dnaJ subfamily B 0.0413 0.1036 0.1036
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0096 0.0096
Brugia malayi calpain D 0.0274 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0274 0.0669 0.1902
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0133 0.0298 0.0298
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0625 0.1591 0.1591
Entamoeba histolytica hypothetical protein 0.0041 0.0057 0.0251
Loa Loa (eye worm) hypothetical protein 0.0252 0.0613 0.0613
Brugia malayi hypothetical protein 0.0041 0.0057 0.0057
Leishmania major hypothetical protein, conserved 0.015 0.0345 0.0874
Brugia malayi cathepsin F-like cysteine proteinase 0.0252 0.0613 0.0613
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Leishmania major hypothetical protein, conserved 0.0274 0.0669 0.1695
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0056 0.0158
Trichomonas vaginalis calpain, putative 0.0274 0.0669 0.1902
Toxoplasma gondii centrin, putative 0.015 0.0345 0.0874
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3826 1 1
Brugia malayi programmed cell death protein 6 0.015 0.0345 0.0345
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0068 0.0128 0.0128
Brugia malayi Trypsin-like protease protein 5 0.006 0.0107 0.0107
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0056 0.0056
Loa Loa (eye worm) prolyl oligopeptidase 0.0671 0.1713 0.1713
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0042 0.0105
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0669 0.0669
Loa Loa (eye worm) glycogen phosphorylase 0.0105 0.0225 0.0225
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Echinococcus multilocularis calmodulin 0.015 0.0345 0.0345
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0025 0.0074
Trichomonas vaginalis calcium binding protein, putative 0.015 0.0345 0.0981
Entamoeba histolytica calpain large subunit domain III containing protein 0.0657 0.1675 0.742
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.006 0.0107 0.0107
Mycobacterium ulcerans transglutaminase family protein 0.0035 0.0041 0.0258
Toxoplasma gondii EF hand domain-containing protein 0.015 0.0345 0.0874
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Brugia malayi Cytochrome P450 family protein 0.0034 0.0038 0.0038
Toxoplasma gondii kringle domain-containing protein 0.0024 0.0012 0.003
Brugia malayi Cathepsin L-like precursor 0.0254 0.0617 0.0617
Leishmania major importin beta-1 subunit, putative 0.0028 0.0024 0.0061
Mycobacterium ulcerans hypothetical protein 0.0039 0.0053 0.0329
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0067 0.0125 0.0356
Loa Loa (eye worm) calpain 0.093 0.2394 0.2394
Loa Loa (eye worm) hypothetical protein 0.0069 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0252 0.0613 0.0613
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0057 0.0057
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0057 0.0057
Entamoeba histolytica protein kinase, putative 0.0657 0.1675 0.742
Entamoeba histolytica cysteine proteinase, putative 0.0878 0.2258 1
Leishmania major calpain family cysteine protease-like protein 0.0274 0.0669 0.1695
Loa Loa (eye worm) hypothetical protein 0.0045 0.0069 0.0069
Mycobacterium ulcerans putative transglutaminase-like protein 0.0035 0.0041 0.0258
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0041 0.0059 0.0059
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0025 0.0064
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0006 0.0018
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0252 0.0613 0.2559
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0225 0.0225
Trypanosoma cruzi cruzipain precursor, putative 0.0254 0.0617 0.0617
Echinococcus multilocularis apoptotic protease activating factor 1 0.0067 0.0125 0.0125
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0252 0.0613 0.0613
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.004 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0115 0.0115
Trypanosoma cruzi calmodulin, putative 0.015 0.0345 0.0345
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0115 0.0115
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0003 0.0009
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Trypanosoma brucei caltractin, putative 0.0154 0.0355 0.0899
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0053 0.015
Schistosoma mansoni reticulocalbin 0.0153 0.0352 0.0352
Echinococcus granulosus cathepsin l1 0.0878 0.2258 0.2258
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Schistosoma mansoni hypothetical protein 0.006 0.0107 0.0107
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0024 0.0069
Echinococcus granulosus programmed cell death protein 0.0154 0.0355 0.0355
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.2394
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.0282 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Brugia malayi carbohydrate phosphorylase 0.0105 0.0225 0.0225
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0041 0.0059 0.0149
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.0059 0.0059
Echinococcus granulosus transmembrane protease serine 3 0.006 0.0107 0.0107
Chlamydia trachomatis glycogen phosphorylase 0.0105 0.0225 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.093 0.2394 0.2394
Brugia malayi cathepsin Z-like cysteine proteinase 0.0252 0.0613 0.0613
Trypanosoma cruzi centrin, putative 0.0154 0.0355 0.0355
Echinococcus granulosus inhibitor of apoptosis protein 0.0146 0.0333 0.0333
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0086 0.0176 0.0176
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.0669 0.1695
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0118 0.0118
Schistosoma mansoni neuronal calcium sensor 0.015 0.0345 0.0345
Schistosoma mansoni hypothetical protein 0.005 0.0083 0.0083
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0669 0.0669
Toxoplasma gondii hypothetical protein 0.0274 0.0669 0.1695
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.06 0.06
Echinococcus granulosus Mastin 0.006 0.0107 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0006 0.0006
Trypanosoma cruzi cysteine proteinase, putative 0.0506 0.128 0.128
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0356 0.0885 0.0885
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.1036 0.1036
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0038 0.0038
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0125 0.0125
Schistosoma mansoni cathepsin S (C01 family) 0.0252 0.0613 0.0613
Echinococcus multilocularis calpain family protein 1, d 0.1824 0.4742 0.4742
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0056 0.0246
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.015 0.0345 0.0874
Echinococcus granulosus proteasome prosome macropain 0.0086 0.0176 0.0176
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0202 0.0202
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, putative 0.0274 0.0669 0.1695
Brugia malayi Peptidase family M13 containing protein 0.0091 0.019 0.019
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0006 0.0006
Giardia lamblia Cathepsin B precursor 0.1357 0.3516 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0006 0.0006
Leishmania major cathepsin L-like protease 0.0978 0.2519 0.6386
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0128 0.0128
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3826 1 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0252 0.0613 0.2559
Schistosoma mansoni cathepsin F (C01 family) 0.0625 0.1591 0.1591
Echinococcus multilocularis caspase 2 0.0067 0.0125 0.0125
Brugia malayi Trypsin family protein 0.006 0.0107 0.0107
Brugia malayi prolyl oligopeptidase family protein 0.0196 0.0465 0.0465
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.015 0.0345 0.0345
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0282 0.1758
Onchocerca volvulus 0.0494 0.1247 0.3091
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0006 0.0006
Giardia lamblia Cathepsin B precursor 0.1357 0.3516 1
Echinococcus granulosus enteropeptidase 0.006 0.0107 0.0107
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0671 0.1713 0.1713
Onchocerca volvulus Glycogen phosphorylase homolog 0.0105 0.0225 0.0547
Echinococcus granulosus cathepsin L cysteine proteinase 0.0878 0.2258 0.2258
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.6068
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0506 0.128 0.128
Entamoeba histolytica hypothetical protein 0.0252 0.0613 0.2714
Leishmania major cathepsin L-like protease 0.0878 0.2258 0.5723
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0053 0.0053
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0057 0.0057
Onchocerca volvulus 0.0878 0.2258 0.5606
Trypanosoma cruzi cysteine peptidase, putative 0.0978 0.2519 0.2519
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0041 0.012
Echinococcus granulosus calpain A 0.093 0.2394 0.2394
Entamoeba histolytica cysteine protease, putative 0.0252 0.0613 0.2714
Echinococcus granulosus Dipeptidyl peptidase 9 0.0329 0.0814 0.0814
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0006 0.0006
Leishmania major centrin, putative 0.015 0.0345 0.0874
Trypanosoma cruzi Aph-1 protein, putative 0.0106 0.0228 0.0228
Brugia malayi steroid hormone receptor 0.0021 0.0006 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0053 0.0154
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0254 0.0617 0.0617
Echinococcus multilocularis calcium uptake protein 1 0.0153 0.0352 0.0352
Loa Loa (eye worm) cysteine protease 0.0878 0.2258 0.2258
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0284
Trichomonas vaginalis calcineurin B subunit, putative 0.015 0.0345 0.0981
Onchocerca volvulus 0.0878 0.2258 0.5606
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0057 0.0057
Echinococcus multilocularis glycoprotein Antigen 5 0.006 0.0107 0.0107
Echinococcus multilocularis tissue type plasminogen activator 0.0024 0.0012 0.0012
Schistosoma mansoni cathepsin F (C01 family) 0.0878 0.2258 0.2258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0625 0.1591 0.4525
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0006 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0057 0.0057
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0013 0.0013
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.015 0.0345 0.0345
Echinococcus multilocularis Mastin 0.006 0.0107 0.0107
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Trichomonas vaginalis centrin, putative 0.015 0.0345 0.0981
Loa Loa (eye worm) calmodulin-like protein 0.015 0.0345 0.0345
Brugia malayi fibroinase precursor 0.0252 0.0613 0.0613
Trypanosoma brucei Calpain-like protein 1.2 0.0274 0.0669 0.1695
Echinococcus granulosus calmodulin 0.015 0.0345 0.0345
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0009 0.0009
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0057 0.0057
Giardia lamblia Alanyl dipeptidyl peptidase 0.0196 0.0465 0.1323
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Schistosoma mansoni centrin 0.015 0.0345 0.0345
Trypanosoma brucei calmodulin, putative 0.0153 0.0352 0.0892
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0629 0.1604 0.4065
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0747 0.1913 0.1913
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0059 0.0167
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0671 0.1713 0.1713
Brugia malayi Pre-SET motif family protein 0.0063 0.0115 0.0115
Echinococcus multilocularis tumor protein p63 0.0358 0.0889 0.0889
Toxoplasma gondii proteasome subunit beta type, putative 0.0086 0.0176 0.0445
Echinococcus granulosus cathepsin L 0.0506 0.128 0.128
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0225 0.0999
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0629 0.1604 0.4065
Trypanosoma brucei calpain, putative 0.0274 0.0669 0.1695
Echinococcus multilocularis EF hand domain containing family member A2 0.0153 0.0352 0.0352
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Brugia malayi EF hand family protein 0.015 0.0345 0.0345
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0086 0.0176 0.0176
Onchocerca volvulus 0.0045 0.0069 0.0158
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0053 0.0329
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0067 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.0613 0.1743
Loa Loa (eye worm) hypothetical protein 0.0274 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0069 0.0132 0.0132
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0057 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0012 0.0012
Trypanosoma brucei mitochondrial calcium uptake 1 0.015 0.0345 0.0874
Giardia lamblia Cathepsin B precursor 0.0252 0.0613 0.1743
Schistosoma mansoni neprilysin-2 (M13 family) 0.0046 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.1521 0.3945 0.3945
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1325 0.343 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0274 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0252 0.0613 0.0613
Echinococcus granulosus calpain A 0.2634 0.6869 0.6869
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0878 0.2258 0.2258
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0024 0.0012 0.005
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0057 0.0057
Schistosoma mansoni inhibitor of apoptosis protein 0.0146 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Trypanosoma cruzi prolyl endopeptidase 0.1521 0.3945 0.3945
Brugia malayi Papain family cysteine protease containing protein 0.0252 0.0613 0.0613
Echinococcus multilocularis cathepsin b 0.3826 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0053 0.0154
Brugia malayi ecdysteroid receptor 0.0021 0.0006 0.0006
Leishmania major kinesin, putative 0.0657 0.1675 0.4246
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0196 0.0465 0.0465
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0252 0.0613 0.1743
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0056 0.0158
Schistosoma mansoni endothelin-converting enzyme-related 0.0022 0.0009 0.0009
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.004 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.015 0.0345 0.0345
Echinococcus granulosus importin subunit beta 1 0.0035 0.0042 0.0042
Trichomonas vaginalis calmodulin, putative 0.015 0.0345 0.0981
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.015 0.0345 0.0345
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0225 0.0999
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0252 0.0613 0.2559
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Loa Loa (eye worm) hypothetical protein 0.0146 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0053 0.0329
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0878 0.2258 0.2258
Loa Loa (eye worm) programmed cell death protein 6 0.0153 0.0352 0.0352
Trypanosoma cruzi calmodulin, putative 0.015 0.0345 0.0345
Brugia malayi Calmodulin-like protein 0.015 0.0345 0.0345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Leishmania major calmodulin, putative 0.015 0.0345 0.0874
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1521 0.3945 0.3945
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0057 0.0057
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0057 0.0057
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0057 0.0057
Trichomonas vaginalis calmodulin, putative 0.015 0.0345 0.0981
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0146 0.0333 0.0333
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0629 0.1604 0.1604
Echinococcus multilocularis calpain A 0.2634 0.6869 0.6869
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.006 0.0107 0.0107
Trypanosoma brucei calpain-like protein, putative 0.093 0.2394 0.6068
Trichomonas vaginalis conserved hypothetical protein 0.0252 0.0613 0.1743
Trichomonas vaginalis calcium binding protein, putative 0.015 0.0345 0.0981
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0057 0.0057
Schistosoma mansoni cathepsin C 0.0252 0.0613 0.0613
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0262 0.0262
Echinococcus granulosus centrin 2 0.015 0.0345 0.0345
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0086 0.0176 0.0512
Giardia lamblia Proteasome subunit beta type 2 0.0041 0.0059 0.0167
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0041 0.0059 0.026
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.015 0.0345 0.0345
Schistosoma mansoni hypothetical protein 0.006 0.0107 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Onchocerca volvulus 0.0878 0.2258 0.5606
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0252 0.0613 0.1743
Schistosoma mansoni calpain-7 (C02 family) 0.093 0.2394 0.2394
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0225 0.0225
Loa Loa (eye worm) proteasome subunit beta type 1 0.0067 0.0125 0.0125
Echinococcus multilocularis acylamino acid releasing enzyme 0.0196 0.0465 0.0465
Trypanosoma brucei Calpain-like protein CALP1.3 0.0274 0.0669 0.1695
Echinococcus multilocularis EF hand domain containing family member A2 0.015 0.0345 0.0345
Trypanosoma cruzi caltractin, putative 0.015 0.0345 0.0345
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0006 0.0006
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0252 0.0613 0.2559
Plasmodium vivax hypothetical protein, conserved 0.0153 0.0352 0.147
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0041 0.0102
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.093 0.2394 0.2394
Echinococcus multilocularis Transglutaminase 0.0035 0.0041 0.0041
Brugia malayi Trypsin family protein 0.006 0.0107 0.0107
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0669 0.0669
Echinococcus granulosus prolyl endopeptidase 0.1521 0.3945 0.3945
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0057 0.0057
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0284
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0115 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0006 0.0006
Echinococcus multilocularis cathepsin b 0.3826 1 1
Loa Loa (eye worm) zinc metallopeptidase 4 0.0022 0.0009 0.0009
Brugia malayi hypothetical protein 0.0247 0.06 0.06
Brugia malayi Papain family cysteine protease containing protein 0.0878 0.2258 0.2258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.0613 0.1743
Trypanosoma cruzi oligopeptidase b 0.0629 0.1604 0.1604
Loa Loa (eye worm) hypothetical protein 0.0148 0.0339 0.0339
Trypanosoma brucei prolyl endopeptidase 0.1521 0.3945 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0252 0.0613 0.0613
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Giardia lamblia Cathepsin B precursor 0.1357 0.3516 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0006 0.0006
Plasmodium falciparum serine repeat antigen 3 0.0252 0.0613 0.2714
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0057 0.0057
Echinococcus granulosus caspase 2 0.0067 0.0125 0.0125
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0057 0.0057
Trypanosoma cruzi major cysteine proteinase, putative 0.0352 0.0874 0.0874
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0196 0.0465 0.0465
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0086 0.0176 0.0445
Echinococcus multilocularis inhibitor of apoptosis protein 0.0146 0.0333 0.0333
Giardia lamblia Cathepsin B precursor 0.0252 0.0613 0.1743
Loa Loa (eye worm) hypothetical protein 0.0091 0.019 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0057 0.0161
Toxoplasma gondii calmodulin CAM1 0.0153 0.0352 0.0892
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0057 0.0057
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0057 0.0057
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Entamoeba histolytica glycogen phosphorylase, putative 0.0045 0.0069 0.0306
Schistosoma mansoni coup transcription factor 0.0021 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0252 0.0613 0.1743
Loa Loa (eye worm) beta-lactamase 0.0039 0.0053 0.0053
Schistosoma mansoni ef hand domain family member A2 0.015 0.0345 0.0345
Entamoeba histolytica glycogenphosphorylase, putative 0.0045 0.0069 0.0306
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Brugia malayi calpain 7 0.093 0.2394 0.2394
Entamoeba histolytica hypothetical protein 0.0028 0.0024 0.0107
Echinococcus multilocularis cathepsin L cysteine protease 0.0878 0.2258 0.2258
Mycobacterium ulcerans proteasome PrcB 0.0086 0.0176 0.1095
Plasmodium vivax vivapain-2 0.0878 0.2258 0.9431
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0262 0.0262
Schistosoma mansoni microtubule-associated protein tau 0.1445 0.3745 0.3745
Plasmodium falciparum serine repeat antigen 6 0.0252 0.0613 0.2714
Plasmodium vivax importin-beta 2, putative 0.0035 0.0042 0.0174
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0041 0.0059 0.026
Brugia malayi gamma-secretase subunit aph-1 0.0271 0.0663 0.0663
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0038 0.0238
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0053 0.0053
Onchocerca volvulus 0.0878 0.2258 0.5606
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0053 0.0154
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0006 0.0006
Plasmodium falciparum proteasome subunit beta type-5 0.0086 0.0176 0.0777
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0252 0.0613 0.2714
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0196 0.0465 0.1323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Brugia malayi calpain family protein 1 0.2481 0.6467 0.6467
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0 0.5
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0146 0.0333 0.0333
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0671 0.1713 0.4251
Schistosoma mansoni calpain (C02 family) 0.093 0.2394 0.2394
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0282 0.0282
Brugia malayi hypothetical protein 0.0041 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0345 0.0981
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0024 0.0069
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.0606 0.1767
Schistosoma mansoni neprilysin 0.0024 0.0013 0.0013
Trichomonas vaginalis calmodulin, putative 0.015 0.0345 0.0981
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0878 0.2258 0.2258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0747 0.1913 0.1913
Brugia malayi Cytochrome P450 family protein 0.0034 0.0038 0.0038
Schistosoma mansoni calpain-2 (C02 family) 0.0274 0.0669 0.0669
Giardia lamblia Cathepsin L precursor 0.0252 0.0613 0.1743
Mycobacterium ulcerans beta-lactamase 0.0039 0.0053 0.0329
Leishmania major calcineurin B subunit, putative 0.015 0.0345 0.0874
Schistosoma mansoni cpg binding protein 0.0031 0.0031 0.0031
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0057 0.0057
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0747 0.1913 0.1913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0038 0.0097
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0196 0.0465 0.1323
Echinococcus granulosus snurportin 1 0.0372 0.0927 0.0927
Brugia malayi nuclear hormone receptor 0.0021 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0043 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1357 0.3516 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0025 0.0074
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0182 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0052 0.0088 0.0088
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0274 0.0669 0.1695
Brugia malayi Cathepsin L-like precursor 0.0878 0.2258 0.2258
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0274 0.0669 0.0669
Entamoeba histolytica cysteine proteinase, putative 0.0878 0.2258 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0064 0.0064
Trichomonas vaginalis calmodulin, putative 0.015 0.0345 0.0981
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3826 1 1
Giardia lamblia Hypothetical protein 0.0252 0.0613 0.1743
Echinococcus granulosus cpg binding protein 0.0031 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0012
Echinococcus multilocularis cathepsin L cysteine protease 0.0878 0.2258 0.2258
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0252 0.0613 0.1743
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0057 0.0161
Plasmodium vivax serine-repeat antigen (SERA) 0.0252 0.0613 0.2559
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0003 0.0009
Schistosoma mansoni reticulocalbin 0.015 0.0345 0.0345
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0006 0.0006
Entamoeba histolytica cysteine proteinase 2 0.0506 0.128 0.5668
Echinococcus granulosus apoptotic protease activating factor 1 0.0067 0.0125 0.0125
Plasmodium falciparum serine repeat antigen 1 0.0252 0.0613 0.2714
Echinococcus multilocularis programmed cell death protein 0.0154 0.0355 0.0355
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0059 0.0167
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0252 0.0613 0.0613
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0671 0.1713 0.1713
Echinococcus granulosus sarcoplasmic calcium binding protein 0.015 0.0345 0.0345
Onchocerca volvulus 0.015 0.0345 0.0845
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0086 0.0176 0.0499
Trypanosoma cruzi cysteine proteinase, putative 0.0506 0.128 0.128
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.08 0.2053 0.2053
Echinococcus granulosus EF HAND 1 calcium binding site 0.015 0.0345 0.0345
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0067 0.0125 0.0125
Trypanosoma brucei centrin, putative 0.015 0.0345 0.0874
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0057 0.0057
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0057 0.0057
Schistosoma mansoni Mername-AA248 (C02 family) 0.093 0.2394 0.2394
Echinococcus multilocularis gamma secretase subunit aph 1 0.0271 0.0663 0.0663
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Onchocerca volvulus 0.0052 0.0088 0.0204
Entamoeba histolytica glycogen phosphorylase, putative 0.0045 0.0069 0.0306
Echinococcus multilocularis cysteine protease 0.0878 0.2258 0.2258
Leishmania major i/6 autoantigen-like protein 0.015 0.0345 0.0874
Mycobacterium tuberculosis Hypothetical protein 0.0035 0.0041 0.012
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Loa Loa (eye worm) proteasome subunit beta type 2 0.0041 0.0059 0.0059
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0196 0.0465 0.0465
Trypanosoma cruzi cysteine peptidase, putative 0.0978 0.2519 0.2519
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.016 0.037 0.037
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0252 0.0613 0.0613
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.0465 0.0465
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0003 0.0009
Leishmania major calmodulin, putative 0.015 0.0345 0.0874
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0669 0.1902
Echinococcus granulosus neurocalcin 0.015 0.0345 0.0345
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.2394
Loa Loa (eye worm) hypothetical protein 0.0069 0.0132 0.0132
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0041 0.0059 0.0059
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0252 0.0613 0.0613
Schistosoma mansoni calpain C (C02 family) 0.093 0.2394 0.2394
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1521 0.3945 1
Loa Loa (eye worm) hypothetical protein 0.0254 0.0617 0.0617
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Giardia lamblia Thymus-specific serine protease precursor 0.004 0.0056 0.0158
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0146 0.0333 0.0333
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Toxoplasma gondii EFHC1, putative 0.015 0.0345 0.0874
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0202 0.0202
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0024 0.0069
Plasmodium vivax proteasome subunit beta type-2, putative 0.0041 0.0059 0.0245
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0006 0.0006
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0225 0.0225
Entamoeba histolytica calcium binding family protein 0.015 0.0345 0.1528
Brugia malayi Kringle domain containing protein 0.0024 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0669 0.1902
Plasmodium vivax centrin-1, putative 0.015 0.0345 0.1441
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Schistosoma mansoni calmodulin 0.015 0.0345 0.0345
Leishmania major hypothetical protein, conserved 0.0024 0.0012 0.003
Loa Loa (eye worm) hypothetical protein 0.0068 0.0128 0.0128
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0091 0.019 0.019
Echinococcus granulosus neuronal calcium sensor 0.015 0.0345 0.0345
Trypanosoma brucei centrin, putative 0.015 0.0345 0.0874
Leishmania major centrin, putative 0.015 0.0345 0.0874
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.093 0.2394 0.2394
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Onchocerca volvulus 0.0878 0.2258 0.5606
Loa Loa (eye worm) EF hand family protein 0.015 0.0345 0.0345
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0006 0.0006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0025 0.0158
Brugia malayi hypothetical protein 0.016 0.037 0.037
Trypanosoma cruzi oligopeptidase b 0.0629 0.1604 0.1604
Trypanosoma brucei calmodulin, putative 0.015 0.0345 0.0874
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0006 0.0006
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.015 0.0345 0.1441
Onchocerca volvulus Huntingtin homolog 0.0148 0.0339 0.0829
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Brugia malayi Trypsin family protein 0.006 0.0107 0.0107
Brugia malayi Cathepsin L-like precursor 0.0878 0.2258 0.2258
Schistosoma mansoni hypothetical protein 0.0274 0.0669 0.0669
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0041 0.0059 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0115 0.0115
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Trypanosoma cruzi I/6 autoantigen, putative 0.015 0.0345 0.0345
Echinococcus granulosus EF hand domain containing family member A2 0.015 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0196 0.0465 0.0465
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0252 0.0613 0.1743
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0006 0.0006
Brugia malayi Cathepsin L-like precursor 0.0625 0.1591 0.1591
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0053 0.0053
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0125 0.0125
Leishmania major hypothetical protein, conserved 0.0039 0.0053 0.0134
Loa Loa (eye worm) hypothetical protein 0.0068 0.0128 0.0128
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0202 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.0465 0.0465
Onchocerca volvulus 0.0625 0.1591 0.3946
Loa Loa (eye worm) hypothetical protein 0.155 0.4023 0.4023
Mycobacterium ulcerans hypothetical protein 0.006 0.0107 0.0667
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0057 0.0161
Trypanosoma cruzi centrin, putative 0.0154 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Onchocerca volvulus Prolyl endopeptidase homolog 0.1521 0.3945 0.9807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.128 0.364
Brugia malayi EF hand family protein 0.0153 0.0352 0.0352
Plasmodium vivax SET domain protein, putative 0.0063 0.0115 0.048
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0329 0.0814 0.0814
Leishmania major programmed cell death 6 protein-like protein 0.015 0.0345 0.0874
Loa Loa (eye worm) hypothetical protein 0.0067 0.0125 0.0125
Giardia lamblia Hypothetical protein 0.0153 0.0352 0.1001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0064 0.0064
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Giardia lamblia Cathepsin B precursor 0.0252 0.0613 0.1743
Trypanosoma brucei C-8 sterol isomerase, putative 0.0356 0.0885 0.2242
Trichomonas vaginalis calmodulin-2, putative 0.015 0.0345 0.0981
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Trichomonas vaginalis calcium binding protein, putative 0.015 0.0345 0.0981
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0356 0.0885 0.0885
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.006 0.0107 0.0107
Onchocerca volvulus 0.005 0.0083 0.0191
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0274 0.0669 0.1695
Echinococcus multilocularis neuronal calcium sensor 0.015 0.0345 0.0345
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0053 0.0053
Brugia malayi beta-lactamase family protein 0.0039 0.0053 0.0053
Brugia malayi Cathepsin L-like cysteine proteinase 0.0625 0.1591 0.1591
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0003 0.0009
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.015 0.0345 0.0981
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2631 0.6862 0.6862
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0006 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0282 0.1758
Brugia malayi peptidase family M13 containing protein 0.0022 0.0009 0.0009
Brugia malayi Cell death protein 3 precursor 0.0067 0.0125 0.0125
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0025 0.0158
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0056 0.0246
Echinococcus multilocularis programmed cell death protein 0.0154 0.0355 0.0355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0878 0.2258 0.6422
Giardia lamblia Proteasome subunit beta type 1 0.0067 0.0125 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0252 0.0613 0.1743
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0724 0.1852 0.1852
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0196 0.0465 0.2061
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0057 0.0057
Echinococcus granulosus calpain 5 0.093 0.2394 0.2394
Mycobacterium tuberculosis Conserved protein 0.0035 0.0041 0.012
Loa Loa (eye worm) hypothetical protein 0.0068 0.0128 0.0128
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0053 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0252 0.0613 0.1743
Giardia lamblia Cysteine protease 0.0252 0.0613 0.1743
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0669 0.1902
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Schistosoma mansoni neuronal calcium sensor 0.015 0.0345 0.0345
Schistosoma mansoni rab 0.015 0.0345 0.0345
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1357 0.3516 0.3516
Trypanosoma cruzi cysteine peptidase, putative 0.0506 0.128 0.128
Toxoplasma gondii cathepsin CPL 0.0878 0.2258 0.5723
Plasmodium vivax hypothetical protein, conserved 0.0196 0.0465 0.1943
Onchocerca volvulus Deterin homolog 0.0146 0.0333 0.0814
Entamoeba histolytica grainin, putative 0.0153 0.0352 0.1559
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0146 0.0333 0.0333
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0252 0.0613 0.1743
Plasmodium falciparum peptidase, putative 0.0196 0.0465 0.2061
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1357 0.3516 0.8911
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0025 0.0158
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0009 0.0009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3826 1 1
Brugia malayi Cathepsin L-like precursor 0.0625 0.1591 0.1591
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Brugia malayi Cathepsin L-like precursor 0.0878 0.2258 0.2258
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0025
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0115 0.0115
Mycobacterium ulcerans zinc metalloprotease 0.0091 0.019 0.1187
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0006 0.0006
Giardia lamblia Cathepsin L-like protease 0.0252 0.0613 0.1743
Leishmania major cathepsin L-like protease 0.0878 0.2258 0.5723
Onchocerca volvulus Cathepsin L homolog 0.0878 0.2258 0.5606
Entamoeba histolytica calmodulin, putative 0.015 0.0345 0.1528
Brugia malayi CXXC zinc finger family protein 0.0029 0.0026 0.0026
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0045 0.0069 0.0431
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0045 0.0069 0.0202
Plasmodium falciparum serine repeat antigen 2 0.0252 0.0613 0.2714
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0252 0.0613 0.2559
Loa Loa (eye worm) hypothetical protein 0.006 0.0107 0.0107
Plasmodium vivax unspecified product 0.0506 0.128 0.5345
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0252 0.0613 0.0613
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0041 0.012
Giardia lamblia Cathepsin L precursor 0.0252 0.0613 0.1743
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0057
Trypanosoma brucei calpain-like protein, putative 0.093 0.2394 0.6068
Echinococcus granulosus cysteine protease 0.0506 0.128 0.128
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0006 0.0006
Schistosoma mansoni survival motor neuron protein 0.005 0.0083 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0006 0.0006
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0091 0.019 0.0555
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0254 0.0617 0.0617
Entamoeba histolytica hypothetical protein, conserved 0.0196 0.0465 0.2061
Trichomonas vaginalis calmodulin, putative 0.015 0.0345 0.0981
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.0613 0.1743
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0252 0.0613 0.2559
Trichomonas vaginalis myosin light chain 1, putative 0.015 0.0345 0.0981
Echinococcus granulosus glycoprotein Antigen 5 0.006 0.0107 0.0107
Onchocerca volvulus Cell death protein 3 homolog 0.0067 0.0125 0.0298
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0053 0.0053
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0225 0.0225
Entamoeba histolytica hypothetical protein, conserved 0.0153 0.0352 0.1559
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0006 0.0006
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0067 0.0125 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0057 0.0161
Brugia malayi calpain 5 0.0657 0.1675 0.1675
Leishmania major cytochrome p450-like protein 0.0034 0.0038 0.0097
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0115 0.0291
Trypanosoma brucei I/6 autoantigen 0.015 0.0345 0.0874
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Brugia malayi RNA, U transporter 1 0.0099 0.021 0.021
Loa Loa (eye worm) cathepsin B 0.1357 0.3516 0.3516
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0282 0.1758
Entamoeba histolytica calmodulin, putative 0.015 0.0345 0.1528
Plasmodium falciparum serine repeat antigen 9 0.0252 0.0613 0.2714
Plasmodium vivax calpain, putative 0.093 0.2394 1
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.015 0.0345 0.0981
Toxoplasma gondii cathepsin CPC1 0.0252 0.0613 0.1553
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Leishmania major cathepsin L-like protease 0.0878 0.2258 0.5723
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.0613 0.1743
Trypanosoma cruzi cysteine peptidase, putative 0.0978 0.2519 0.2519
Echinococcus multilocularis prolyl endopeptidase 0.1521 0.3945 0.3945
Trichomonas vaginalis calmodulin, putative 0.0154 0.0355 0.1009
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0057 0.0057
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0057 0.0057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0006 0.0006
Mycobacterium ulcerans lipase LipD 0.0039 0.0053 0.0329
Trichomonas vaginalis hypothetical protein 0.0274 0.0669 0.1902
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Loa Loa (eye worm) fibroinase 0.0878 0.2258 0.2258
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0274 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0252 0.0613 0.2714
Loa Loa (eye worm) hypothetical protein 0.0252 0.0613 0.0613
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.1824 0.4742 0.4742
Mycobacterium tuberculosis Probable peptidase 0.0629 0.1604 0.4675
Brugia malayi prolyl oligopeptidase family protein 0.0671 0.1713 0.1713
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2631 0.6862 0.6862
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0629 0.1604 0.1604
Onchocerca volvulus 0.006 0.0107 0.0252
Schistosoma mansoni neuronal calcium sensor 0.015 0.0345 0.0345
Echinococcus multilocularis enteropeptidase 0.006 0.0107 0.0107
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0006 0.0006
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0056 0.0246
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0128 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0345 0.0981
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0329 0.0814 0.2062
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0057 0.0057
Entamoeba histolytica cysteine proteinase, putative 0.0625 0.1591 0.7046
Onchocerca volvulus 0.0878 0.2258 0.5606
Plasmodium falciparum serine repeat antigen 7 0.0252 0.0613 0.2714
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Loa Loa (eye worm) prolyl oligopeptidase 0.0196 0.0465 0.0465
Echinococcus granulosus microtubule associated protein 2 0.1445 0.3745 0.3745
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0057 0.0057
Brugia malayi MH2 domain containing protein 0.0119 0.0262 0.0262
Schistosoma mansoni cathepsin s 0.0254 0.0617 0.0617
Echinococcus multilocularis microtubule associated protein 2 0.1445 0.3745 0.3745
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0053 0.0053
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0067 0.0125 0.0125
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.006 0.0107 0.0107
Schistosoma mansoni centrin-related 0.015 0.0345 0.0345
Onchocerca volvulus 0.006 0.0107 0.0252
Trypanosoma brucei oligopeptidase b 0.0629 0.1604 0.4065
Plasmodium vivax vivapain-2 0.0878 0.2258 0.9431
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0284
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Echinococcus granulosus endothelin converting enzyme 1 0.0091 0.019 0.019
Trypanosoma brucei kinesin, putative 0.0657 0.1675 0.4246
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0038 0.0038
Giardia lamblia Encystation-specific protease 0.0252 0.0613 0.1743
Entamoeba histolytica cysteine protease, putative 0.0878 0.2258 1
Brugia malayi Papain family cysteine protease containing protein 0.0252 0.0613 0.0613
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0025 0.0158
Plasmodium vivax serine-repeat antigen (SERA) 0.0252 0.0613 0.2559
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0056 0.0056
Entamoeba histolytica grainin 2 0.0154 0.0355 0.1572
Echinococcus granulosus tumor protein p63 0.0358 0.0889 0.0889
Entamoeba histolytica cysteine protease, putative 0.0252 0.0613 0.2714
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0252 0.0613 0.2714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.0613 0.1743
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0025 0.0112
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0038 0.0038
Plasmodium vivax vivapain-1 0.0506 0.128 0.5345
Trypanosoma brucei hypothetical protein 0.0274 0.0669 0.1695
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0158
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0274 0.0669 0.1695
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Plasmodium falciparum serine repeat antigen 8 0.0252 0.0613 0.2714
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0506 0.128 0.128
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0878 0.2258 0.6422
Trichomonas vaginalis calcium binding proteins, putative 0.015 0.0345 0.0981
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.2394
Onchocerca volvulus 0.0039 0.0053 0.0117
Plasmodium falciparum calpain 0.0274 0.0669 0.2963
Loa Loa (eye worm) hypothetical protein 0.006 0.0107 0.0107
Brugia malayi beta-lactamase 0.0039 0.0053 0.0053
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.015 0.0345 0.0345
Trypanosoma brucei hypothetical protein, conserved 0.015 0.0345 0.0874
Echinococcus granulosus expressed protein 0.079 0.2025 0.2025
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Loa Loa (eye worm) calpain family protein 1 0.1824 0.4742 0.4742
Trypanosoma brucei cysteine peptidase C (CPC) 0.1357 0.3516 0.8911
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0057 0.0057
Brugia malayi Cytochrome P450 family protein 0.0055 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0625 0.1591 0.1591
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0086 0.0176 0.0777
Trichomonas vaginalis set domain proteins, putative 0.0494 0.1247 0.3545
Trichomonas vaginalis centrin, putative 0.015 0.0345 0.0981
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0006 0.0006
Brugia malayi PXA domain containing protein 0.0041 0.0057 0.0057
Plasmodium falciparum centrin-1 0.015 0.0345 0.1528
Schistosoma mansoni hypothetical protein 0.015 0.0345 0.0345
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0107 0.0107
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0196 0.0465 0.2061
Onchocerca volvulus 0.0029 0.0026 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0006 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0053 0.022
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0057 0.0057
Mycobacterium ulcerans hypothetical protein 0.0035 0.0041 0.0258
Loa Loa (eye worm) hypothetical protein 0.0069 0.0132 0.0132
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2481 0.6467 0.6467
Giardia lamblia Glycogen phosphorylase 0.0105 0.0225 0.0641
Plasmodium falciparum importin beta, putative 0.0035 0.0042 0.0184
Brugia malayi Serine carboxypeptidase S28 family protein 0.004 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0252 0.0613 0.1743
Loa Loa (eye worm) ctsf protein 0.0878 0.2258 0.2258
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0053 0.015
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Trypanosoma brucei Calpain-like protein 2 0.0274 0.0669 0.1695
Loa Loa (eye worm) trypsin family protein 0.006 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0057
Echinococcus granulosus cathepsin L 0.0252 0.0613 0.0613
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0878 0.2258 0.6422
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0006 0.0006
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0067 0.0125 0.0125
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0086 0.0176 0.0176
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0067 0.0125 0.0317
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0053 0.015
Echinococcus multilocularis calbindin 32 0.0153 0.0352 0.0352
Onchocerca volvulus 0.004 0.0056 0.0124
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.006 0.0107 0.0107
Entamoeba histolytica cysteine proteinase, putative 0.0506 0.128 0.5668
Schistosoma mansoni gamma-secretase subunit aph-1 0.0271 0.0663 0.0663
Schistosoma mansoni hypothetical protein 0.0413 0.1036 0.1036
Trichomonas vaginalis conserved hypothetical protein 0.0196 0.0465 0.1323
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0202 0.0202
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.0059 0.0059
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0629 0.1604 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0158
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Schistosoma mansoni cathepsin B (C01 family) 0.0252 0.0613 0.0613
Loa Loa (eye worm) hypothetical protein 0.006 0.0107 0.0107
Brugia malayi Papain family cysteine protease containing protein 0.0506 0.128 0.128
Toxoplasma gondii hypothetical protein 0.0196 0.0465 0.1179
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.6068
Trichomonas vaginalis esterase, putative 0.0039 0.0053 0.015
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0225 0.0641
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3826 1 1
Trypanosoma cruzi I/6 autoantigen, putative 0.015 0.0345 0.0345
Trypanosoma cruzi conserved protein 0.0274 0.0669 0.0669
Echinococcus multilocularis EF HAND 1, calcium binding site 0.015 0.0345 0.0345
Giardia lamblia Serine peptidase, putative 0.004 0.0056 0.0158
Giardia lamblia Hypothetical protein 0.0252 0.0613 0.1743
Schistosoma mansoni hypothetical protein 0.0035 0.0041 0.0041
Plasmodium vivax proteasome subunit beta type-1, putative 0.0067 0.0125 0.0523
Trypanosoma cruzi centrin-3 0.0154 0.0355 0.0355
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.6068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Onchocerca volvulus Cathepsin L homolog 0.0878 0.2258 0.5606
Loa Loa (eye worm) hypothetical protein 0.015 0.0345 0.0345
Mycobacterium ulcerans hypothetical protein 0.0029 0.0025 0.0158
Onchocerca volvulus 0.006 0.0107 0.0252
Trypanosoma brucei protein I/6 0.015 0.0345 0.0874
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0057
Brugia malayi Proteasome A-type and B-type family protein 0.0086 0.0176 0.0176
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0252 0.0613 0.0613
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0669 0.0669
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0669 0.1902
Loa Loa (eye worm) hypothetical protein 0.006 0.0107 0.0107
Schistosoma mansoni importin beta-1 0.0035 0.0042 0.0042
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0146 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0022 0.0009 0.0009
Plasmodium vivax vivapain-3 0.0506 0.128 0.5345
Toxoplasma gondii troponin c, isotype gamma, putative 0.015 0.0345 0.0874
Loa Loa (eye worm) hypothetical protein 0.2481 0.6467 0.6467
Onchocerca volvulus 0.0024 0.0012 0.0016
Plasmodium vivax unspecified product 0.0252 0.0613 0.2559
Onchocerca volvulus Huntingtin homolog 0.0148 0.0339 0.0829
Trypanosoma brucei antigen, putative 0.093 0.2394 0.6068
Trichomonas vaginalis peptide N-glycanase, putative 0.0035 0.0041 0.0118
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0006 0.0006
Trichomonas vaginalis calcium binding protein, putative 0.0154 0.0355 0.1009
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0247 0.06 0.06
Brugia malayi Pre-SET motif family protein 0.0434 0.1089 0.1089
Trypanosoma cruzi major cysteine proteinase, putative 0.0252 0.0613 0.0613
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0252 0.0613 0.2714
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0669 0.0669
Brugia malayi calpain 5 0.0274 0.0669 0.0669
Entamoeba histolytica cysteine proteinase 1, putative 0.0506 0.128 0.5668
Trypanosoma brucei prolyl oligopeptidase, putative 0.0629 0.1604 0.4065
Giardia lamblia Cathepsin L precursor 0.0252 0.0613 0.1743
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0196 0.0465 0.1179
Echinococcus granulosus cathepsin b 0.3826 1 1
Schistosoma mansoni memapsin-2 (A01 family) 0.0446 0.1121 0.1121
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0071 0.0071
Mycobacterium tuberculosis Conserved protein 0.0039 0.0053 0.0154
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0025 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0006 0.0006
Giardia lamblia Transglutaminase/protease, putative 0.0035 0.0041 0.0118
Echinococcus granulosus tissue type plasminogen activator 0.0024 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.3826 1 1
Schistosoma mansoni caspase-7 (C14 family) 0.0067 0.0125 0.0125
Brugia malayi hypothetical protein 0.0148 0.0339 0.0339
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0025 0.0064
Trypanosoma brucei calpain-like protein, putative 0.093 0.2394 0.6068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0506 0.128 0.3243
Loa Loa (eye worm) hypothetical protein 0.0625 0.1591 0.1591
Schistosoma mansoni cpg binding protein 0.0031 0.0031 0.0031
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0057 0.0057
Trypanosoma cruzi kinesin, putative 0.0657 0.1675 0.1675
Onchocerca volvulus 0.006 0.0107 0.0252
Onchocerca volvulus 0.0252 0.0613 0.1511
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0071 0.0071
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0053 0.015
Toxoplasma gondii serine carboxypeptidase s28 protein 0.004 0.0056 0.0141
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0056 0.0056
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0022 0.0009 0.0009
Schistosoma mansoni calmodulin related calcium binding protein 0.015 0.0345 0.0345
Giardia lamblia Hypothetical protein 0.0035 0.0041 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0625 0.1591 0.4525
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1521 0.3945 0.3945
Brugia malayi cathepsin L-like cysteine proteinase 0.0252 0.0613 0.0613
Leishmania major cathepsin L-like protease 0.0978 0.2519 0.6386
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0057 0.0161
Plasmodium vivax unspecified product 0.0254 0.0617 0.2577
Loa Loa (eye worm) hypothetical protein 0.0878 0.2258 0.2258
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0057 0.0057
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.015 0.0345 0.1528
Schistosoma mansoni mitochondrial solute carrier 0.015 0.0345 0.0345
Brugia malayi proteasome subunit beta type 2 0.0041 0.0059 0.0059
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0006 0.0006
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.004 0.0056 0.0056
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0025 0.0025
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.0465 0.2061
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0284
Giardia lamblia Cathepsin B precursor 0.0252 0.0613 0.1743
Brugia malayi cathepsin L precursor 0.0252 0.0613 0.0613
Loa Loa (eye worm) hypothetical protein 0.006 0.0107 0.0107
Brugia malayi nuclear receptor NHR-88 0.0021 0.0006 0.0006
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0271 0.0663 0.0663
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0252 0.0613 0.0613
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0057 0.0057
Echinococcus granulosus calpain 7 C02 family 0.093 0.2394 0.2394
Brugia malayi PXA domain containing protein 0.0041 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.006 0.0107 0.0107
Mycobacterium ulcerans hypothetical protein 0.0035 0.0041 0.0258
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0254 0.0617 0.0617
Echinococcus multilocularis centrin 2 0.015 0.0345 0.0345
Echinococcus multilocularis cathepsin L 0.0506 0.128 0.128
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0202 0.0202
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0252 0.0613 0.0613
Schistosoma mansoni cathepsin F (C01 family) 0.0878 0.2258 0.2258
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0057 0.0057
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0927 0.0927
Plasmodium falciparum cysteine proteinase falcipain 3 0.0878 0.2258 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.0282 0.0715
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0115 0.0115
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0025 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0252 0.0613 0.1743
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0 0.5
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Entamoeba histolytica cysteine protease, putative 0.0252 0.0613 0.2714
Echinococcus multilocularis Glycosyl transferase, family 35 0.0105 0.0225 0.0225
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0006 0.0006
Echinococcus multilocularis proteasome (prosome, macropain) 0.0086 0.0176 0.0176
Loa Loa (eye worm) calpain D 0.0274 0.0669 0.0669
Leishmania major hypothetical protein, conserved 0.0153 0.0352 0.0892
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0057 0.0057
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0006 0.0006
Trichomonas vaginalis calmodulin, putative 0.0153 0.0352 0.1001
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0252 0.0613 0.1743
Loa Loa (eye worm) hypothetical protein 0.0252 0.0613 0.0613
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0006 0.0006
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0629 0.1604 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0878 0.2258 0.2258
Brugia malayi prolyl oligopeptidase family protein 0.1521 0.3945 0.3945
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Onchocerca volvulus 0.0039 0.0053 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0202 0.0202
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0252 0.0613 0.0613
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0042
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0053 0.015
Onchocerca volvulus 0.155 0.4023 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.0282 0.0822
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0006 0.0006
Trichomonas vaginalis calmodulin, putative 0.015 0.0345 0.0981
Entamoeba histolytica cysteine proteinase, putative 0.0506 0.128 0.5668
Loa Loa (eye worm) hypothetical protein 0.0091 0.019 0.019
Mycobacterium tuberculosis Conserved protein 0.0039 0.0053 0.0154
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.0282 0.0282
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0057 0.0057
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0146 0.0333 0.0333
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0057 0.0057
Giardia lamblia Cysteine protease 0.0252 0.0613 0.1743
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Mycobacterium tuberculosis Long conserved protein 0.0035 0.0041 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.0613 0.1743
Echinococcus multilocularis calumenin 0.0153 0.0352 0.0352
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2631 0.6862 0.6862
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.6068
Giardia lamblia Cysteine protease 0.0252 0.0613 0.1743
Loa Loa (eye worm) calpain 5 0.0657 0.1675 0.1675
Giardia lamblia Cathepsin L precursor 0.0252 0.0613 0.1743
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0056 0.0158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0202 0.0202
Trypanosoma cruzi kinesin, putative 0.0657 0.1675 0.1675
Mycobacterium tuberculosis Conserved protein 0.0039 0.0053 0.0154
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0252 0.0613 0.2714
Brugia malayi calpain family protein 1 0.2481 0.6467 0.6467
Onchocerca volvulus 0.0067 0.0125 0.0298
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Brugia malayi Importin beta-1 subunit 0.0035 0.0042 0.0042
Leishmania major protein kinase, putative 0.015 0.0345 0.0874
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0669 0.1902
Trichomonas vaginalis calpain, putative 0.0274 0.0669 0.1902
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Schistosoma mansoni cercarial elastase (S01 family) 0.006 0.0107 0.0107
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0006 0.0006
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0042 0.0105
Schistosoma mansoni hypothetical protein 0.0372 0.0927 0.0927
Entamoeba histolytica cysteine proteinase, putative 0.0506 0.128 0.5668
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0006 0.0006
Echinococcus multilocularis neurocalcin 0.015 0.0345 0.0345
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0107 0.0107
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.093 0.2394 0.2394
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0252 0.0613 0.1743
Entamoeba histolytica cysteine protease, putative 0.0252 0.0613 0.2714
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0057 0.0161
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Loa Loa (eye worm) hypothetical protein 0.0254 0.0617 0.0617
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0329 0.0814 0.2062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0506 0.128 0.364
Trypanosoma brucei calpain-like protein, putative 0.093 0.2394 0.6068
Brugia malayi hypothetical protein 0.0043 0.0064 0.0064
Giardia lamblia Cathepsin L precursor 0.0252 0.0613 0.1743
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.0613 0.1743
Echinococcus granulosus gamma secretase subunit aph 1 0.0271 0.0663 0.0663
Echinococcus granulosus Glycosyl transferase family 35 0.0105 0.0225 0.0225
Echinococcus granulosus cathepsin l1 0.0625 0.1591 0.1591
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0057 0.0161
Entamoeba histolytica calpain family cysteine protease, putative 0.0274 0.0669 0.2963
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0506 0.128 0.128
Leishmania major proteasome beta 5 subunit, putative 0.0086 0.0176 0.0445
Echinococcus granulosus cathepsin L cysteine protease 0.0506 0.128 0.128
Giardia lamblia Cysteine protease 0.0252 0.0613 0.1743
Brugia malayi cathepsin F-like cysteine proteinase 0.0254 0.0617 0.0617
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.004 0.0056 0.0056
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0057 0.0057
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0006 0.0028
Schistosoma mansoni calpain-7 (C02 family) 0.093 0.2394 0.2394
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0053 0.0134
Schistosoma mansoni hypothetical protein 0.0024 0.0012 0.0012
Echinococcus granulosus calumenin 0.0153 0.0352 0.0352
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0329 0.0814 0.0814
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.093 0.2394 0.6068
Echinococcus multilocularis cpg binding protein 0.0031 0.0031 0.0031
Echinococcus multilocularis cathepsin L 0.0252 0.0613 0.0613
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0252 0.0613 0.2559
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0067 0.0125 0.0555
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0878 0.2258 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0057
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0025 0.0112
Trypanosoma brucei Calpain-like protein 1.1 0.0274 0.0669 0.1695
Echinococcus multilocularis cysteine protease 0.0878 0.2258 0.2258
Onchocerca volvulus 0.0035 0.0041 0.0089
Onchocerca volvulus 0.006 0.0107 0.0252
Toxoplasma gondii cathepsin CPC2 0.0252 0.0613 0.1553
Mycobacterium leprae Probable lipase LipE 0.0039 0.0053 0.0174
Toxoplasma gondii centrin 0.015 0.0345 0.0874
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.0613 0.1743
Loa Loa (eye worm) hypothetical protein 0.006 0.0107 0.0107
Leishmania major calmodulin-like protein 0.015 0.0345 0.0874
Leishmania major cathepsin L-like protease 0.0878 0.2258 0.5723
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Toxoplasma gondii preprocathepsin c precursor, putative 0.0252 0.0613 0.1553
Brugia malayi Thioredoxin family protein 0.0035 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0041 0.0057 0.0251
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0978 0.2519 0.6386
Entamoeba histolytica hypothetical protein 0.0041 0.0057 0.0251
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.0669
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0506 0.128 0.128
Echinococcus multilocularis calmodulin 0.015 0.0345 0.0345
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.015 0.0345 0.0874
Echinococcus multilocularis expressed protein 0.079 0.2025 0.2025
Brugia malayi Cathepsin L-like precursor 0.0878 0.2258 0.2258
Brugia malayi calcium-binding protein 0.015 0.0345 0.0345
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0006 0.0006
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0629 0.1604 0.4675
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0274 0.0669 0.0669
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0006 0.0006
Leishmania major proteasome beta 2 subunit, putative 0.0041 0.0059 0.0149
Leishmania major cysteine peptidase A (CPA) 0.0878 0.2258 0.5723
Trypanosoma cruzi cruzipain precursor, putative 0.0978 0.2519 0.2519
Schistosoma mansoni glycogen phosphorylase 0.0045 0.0069 0.0069
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0153 0.0352 0.0352
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0057 0.0057
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0025 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0025
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0115 0.0115
Entamoeba histolytica calcium-binding protein, putative 0.015 0.0345 0.1528
Trypanosoma brucei Aph-1 protein, putative 0.0106 0.0228 0.0578
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0225 0.0225
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0669 0.1695
Echinococcus multilocularis hypothetical protein 0.093 0.2394 0.2394
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0086 0.0176 0.0952
Toxoplasma gondii cathepsin B 0.1357 0.3516 0.8911
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0006 0.0006
Onchocerca volvulus 0.0153 0.0352 0.0862
Brugia malayi hypothetical protein 0.0067 0.0125 0.0125
Entamoeba histolytica cysteine protease, putative 0.0506 0.128 0.5668
Leishmania major cathepsin L-like protease 0.0878 0.2258 0.5723
Toxoplasma gondii ABC1 family protein 0.0039 0.0053 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0878 0.2258 0.6422
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0252 0.0613 0.2714
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0878 0.2258 1
Leishmania major C-8 sterol isomerase-like protein 0.0356 0.0885 0.2242
Plasmodium vivax proteasome subunit beta type-5, putative 0.0086 0.0176 0.0733
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.004 0.0056 0.0158

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 12.9953 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 15.1014 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 19.9526 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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