Detailed information for compound 1341414

Basic information

Technical information
  • TDR Targets ID: 1341414
  • Name: methyl 4-[(E)-1-[(4-methoxycarbonylbenzoyl)am ino]-2-propylhex-2-enyl]benzoate
  • MW: 437.528 | Formula: C26H31NO5
  • H donors: 1 H acceptors: 3 LogP: 6.05 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC/C=C(/C(c1ccc(cc1)C(=O)OC)NC(=O)c1ccc(cc1)C(=O)OC)\CCC
  • InChi: 1S/C26H31NO5/c1-5-7-9-18(8-6-2)23(19-10-14-21(15-11-19)25(29)31-3)27-24(28)20-12-16-22(17-13-20)26(30)32-4/h9-17,23H,5-8H2,1-4H3,(H,27,28)/b18-9+
  • InChiKey: NKJNKSSHBFOMDJ-GIJQJNRQSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 4-[(E)-1-[(4-methoxycarbonylbenzoyl)amino]-2-propyl-hex-2-enyl]benzoate
  • 4-[(E)-1-[[(4-methoxycarbonylphenyl)-oxomethyl]amino]-2-propylhex-2-enyl]benzoic acid methyl ester
  • 4-[(E)-1-[(4-carbomethoxybenzoyl)amino]-2-propyl-hex-2-enyl]benzoic acid methyl ester
  • methyl 4-[(E)-1-[(4-methoxycarbonylphenyl)carbonylamino]-2-propyl-hex-2-enyl]benzoate
  • SDCCGMLS-0090944.P001
  • NCGC00074387-01
  • UPCMLD01ACMC001179

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Cathepsin B precursor 0.0239 0.0687 0.2175
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Onchocerca volvulus 0.1338 0.4045 0.8596
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Trypanosoma brucei centrin, putative 0.0127 0.0346 0.0715
Leishmania major hypothetical protein, conserved 0.0127 0.0346 0.0715
Leishmania major hypothetical protein, conserved 0.0208 0.0592 0.1239
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0086 0.0076
Leishmania major oligopeptidase b 0.0643 0.1923 0.4074
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0094 0.0244 0.0274
Schistosoma mansoni neprilysin-2 (M13 family) 0.0047 0.01 0.0105
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.003 0.0043
Schistosoma mansoni hypothetical protein 0.0323 0.0944 0.1092
Brugia malayi cathepsin B-like cysteine proteinase 0.2816 0.8566 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0044 0.009 0.0095
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0086 0.0243
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0026 0.0034
Brugia malayi MH2 domain containing protein 0.0136 0.0373 0.0424
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0024 0.0031
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0086 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Brugia malayi calpain 5 0.0567 0.1688 0.1962
Brugia malayi Cell death protein 3 precursor 0.0131 0.0355 0.0404
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0023 0.0015
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0046
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0239 0.0687 0.0793
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0239 0.0687 0.2175
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Entamoeba histolytica cysteine protease, putative 0.0944 0.2841 1
Mycobacterium ulcerans zinc metalloprotease 0.0093 0.0241 0.1209
Entamoeba histolytica hypothetical protein 0.0072 0.0177 0.0588
Echinococcus multilocularis calmodulin 0.0127 0.0346 0.0336
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0155 0.017
Schistosoma mansoni cpg binding protein 0.0031 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0286 0.0829 0.0959
Brugia malayi proteasome subunit beta type 1 0.007 0.0169 0.0186
Giardia lamblia Transglutaminase/protease, putative 0.0247 0.0712 0.2253
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0023 0.0015
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0023 0.0015
Trypanosoma cruzi calmodulin, putative 0.0127 0.0346 0.0393
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0101 0.0321
Loa Loa (eye worm) histone deacetylase 11 0.0044 0.009 0.0095
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0112 0.0299 0.0337
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2267 0.6887 0.8038
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0088 0.025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0075 0.0065
Plasmodium falciparum calpain 0.0235 0.0676 0.2355
Onchocerca volvulus 0.0112 0.0299 0.0636
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0762 0.2285 0.266
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.0676 0.2139
Brugia malayi RNA, U transporter 1 0.0086 0.0219 0.0245
Echinococcus multilocularis expressed protein 0.0824 0.2475 0.2468
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0086 0.0088
Loa Loa (eye worm) hypothetical protein 0.0112 0.0299 0.0339
Schistosoma mansoni histone deacetylase 0.0091 0.0235 0.0263
Loa Loa (eye worm) histone deacetylase 7A 0.0102 0.0269 0.0304
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Entamoeba histolytica grainin, putative 0.013 0.0353 0.121
Trypanosoma brucei proteasome beta 6 subunit 0.007 0.0169 0.0338
Toxoplasma gondii EF hand domain-containing protein 0.0127 0.0346 0.0715
Toxoplasma gondii subtilisin SUB12 0.003 0.0049 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0592 0.068
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0288 0.0325
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0075 0.0076
Schistosoma mansoni neuronal calcium sensor 0.0127 0.0346 0.0393
Trypanosoma brucei calpain-like protein, putative 0.0802 0.2408 0.5107
Loa Loa (eye worm) hypothetical protein 0.0065 0.0154 0.017
Brugia malayi cathepsin F-like cysteine proteinase 0.0286 0.0829 0.0958
Brugia malayi Cathepsin L-like precursor 0.0658 0.1968 0.2288
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0201 0.057 0.0655
Echinococcus granulosus histone deacetylase 6 0.0109 0.0289 0.0326
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0086 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0023 0.0016
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.003 0.0043
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0086 0.0088
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0274
Plasmodium falciparum cysteine proteinase falcipain 3 0.0944 0.2841 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0023 0.0013
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0239 0.0687 0.2175
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0235 0.0722
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0012 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0066 0.0179
Brugia malayi Papain family cysteine protease containing protein 0.0525 0.156 0.1812
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0025 0.0018
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0239 0.0687 0.0792
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.003 0.0048 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0069 0.019
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.013 0.0355 0.0734
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0239 0.0687 0.2175
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0065 0.0295
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0239 0.0687 0.0792
Trichomonas vaginalis calmodulin, putative 0.0127 0.0346 0.1079
Schistosoma mansoni hypothetical protein 0.0094 0.0244 0.0274
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0274
Toxoplasma gondii cathepsin CPC2 0.0239 0.0687 0.1442
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0239 0.0687 0.0792
Leishmania major hypothetical protein, conserved 0.0047 0.0099 0.019
Trypanosoma cruzi cysteine protease, putative 0.0525 0.156 0.1812
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0023 0.0016
Echinococcus multilocularis histone deacetylase 6 0.0102 0.0269 0.0259
Brugia malayi Blistered cuticle protein 3 0.0065 0.0155 0.017
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0027 0.002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.0025 0.0018
Schistosoma mansoni caspase-3 (C14 family) 0.0018 0.0012 0.0003
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0101 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0007
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.029 0.0901
Trypanosoma brucei glucosidase, putative 0.0037 0.0069 0.0126
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0086 0.0088
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0023 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0944 0.2841 0.9092
Echinococcus granulosus calpain 5 0.0802 0.2408 0.2803
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0944 0.2841 0.9092
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.013 0.0355 0.0853
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.0687 0.2175
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0127 0.0346 0.1187
Brugia malayi PXA domain containing protein 0.0042 0.0086 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0067 0.016 0.0175
Trypanosoma brucei histone deacetylase 3 0.0102 0.0269 0.0552
Onchocerca volvulus 0.003 0.0049 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.0687 0.2175
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0084 0.0262
Trypanosoma brucei prolyl oligopeptidase, putative 0.0643 0.1923 0.4074
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0299 0.0716
Plasmodium vivax unspecified product 0.0286 0.0829 0.2897
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.0465 0.0532
Trichomonas vaginalis esterase, putative 0.0036 0.0065 0.0178
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0235 0.0676 0.0778
Trichomonas vaginalis calmodulin, putative 0.0131 0.0357 0.1114
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.003 0.0059
Schistosoma mansoni rab 0.0127 0.0346 0.0393
Echinococcus multilocularis calmodulin 0.0127 0.0346 0.0336
Leishmania major calpain family cysteine protease-like protein 0.0235 0.0676 0.1418
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0606 0.1808 0.2102
Plasmodium falciparum proteasome subunit beta type-1, putative 0.007 0.0169 0.0564
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0127 0.0346 0.0715
Onchocerca volvulus Deterin homolog 0.0155 0.0429 0.0912
Trypanosoma brucei metacaspase MCA2 0.0018 0.0012 0.0005
Echinococcus granulosus glycogen phosphorylase 0.0109 0.029 0.0328
Leishmania major histone deacetylase, putative 0.0091 0.0235 0.0479
Echinococcus multilocularis histone deacetylase 6 0.0109 0.0289 0.0279
Trypanosoma cruzi cysteine peptidase, putative 0.0286 0.0829 0.0958
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Echinococcus multilocularis gamma secretase subunit aph 1 0.0254 0.0731 0.0722
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.01 0.0105
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0235 0.0676 0.0778
Onchocerca volvulus 0.0658 0.1968 0.4181
Brugia malayi hypothetical protein 0.003 0.0048 0.0045
Echinococcus multilocularis acylamino acid releasing enzyme 0.0201 0.057 0.0561
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0086 0.0243
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0054 0.0118
Entamoeba histolytica prolyl oligopeptidase family protein 0.0201 0.057 0.1979
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0086 0.0088
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0023 0.0015
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0355 0.1805
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Brugia malayi Cathepsin L-like precursor 0.0944 0.2841 0.3309
Echinococcus granulosus calpain 0.0802 0.2408 0.2803
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0088 0.0166
Toxoplasma gondii hypothetical protein 0.0201 0.057 0.1193
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0023 0.0016
Loa Loa (eye worm) aspartic protease BmAsp-2 0.003 0.0048 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0007
Schistosoma mansoni neuronal calcium sensor 0.0127 0.0346 0.0393
Mycobacterium ulcerans hypothetical protein 0.0247 0.0712 0.3671
Onchocerca volvulus Cell death protein 3 homolog 0.0131 0.0355 0.0755
Onchocerca volvulus 0.0046 0.0097 0.0206
Loa Loa (eye worm) inositol-1 0.0036 0.0066 0.0066
Onchocerca volvulus 0.0155 0.0429 0.0912
Echinococcus granulosus cysteine protease 0.0525 0.156 0.1812
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0086 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0023 0.0016
Trichomonas vaginalis calcium binding protein, putative 0.0131 0.0357 0.1114
Entamoeba histolytica calmodulin, putative 0.0127 0.0346 0.1187
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0101 0.0231
Echinococcus multilocularis centrin 2 0.0127 0.0346 0.0336
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0023 0.0016
Onchocerca volvulus 0.0036 0.0065 0.0139
Loa Loa (eye worm) hypothetical protein 0.003 0.0048 0.0046
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.038 0.1939
Toxoplasma gondii proteasome subunit beta type 1, putative 0.007 0.0169 0.0338
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.007 0.0169 0.0338
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0023 0.0015
Onchocerca volvulus 0.013 0.0353 0.0749
Brugia malayi ecdysteroid receptor 0.0022 0.0023 0.0015
Echinococcus granulosus Dipeptidyl peptidase 9 0.0338 0.0989 0.1145
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0086 0.0243
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0643 0.1923 0.4074
Plasmodium vivax hypothetical protein, conserved 0.013 0.0353 0.1213
Brugia malayi aspartic protease BmAsp-1, identical 0.003 0.0048 0.0045
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0026 0.0132
Leishmania major cathepsin L-like protease 0.1047 0.3159 0.6704
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0355 0.0403
Loa Loa (eye worm) hypothetical protein 0.0489 0.1451 0.1685
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Toxoplasma gondii calcium-dependent protein kinase 0.013 0.0353 0.0729
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0274
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.003 0.011
Schistosoma mansoni hypothetical protein 0.0421 0.1244 0.1442
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0084 0.0074
Plasmodium falciparum plasmepsin IV 0.003 0.0048 0.0138
Leishmania major cathepsin L-like protease 0.1047 0.3159 0.6704
Echinococcus granulosus histone deacetylase 6 0.0102 0.0269 0.0303
Echinococcus granulosus glycogen phosphorylase 0.0109 0.029 0.0328
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0166 0.0184
Schistosoma mansoni microtubule-associated protein tau 0.149 0.4511 0.526
Trichomonas vaginalis calpain, putative 0.0235 0.0676 0.2139
Echinococcus multilocularis muscleblind protein 1 0.0294 0.0855 0.0846
Mycobacterium leprae putative cytochrome p450 0.0024 0.003 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.0687 0.2175
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0023 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.057 0.1799
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0338 0.0989 0.2086
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0592 0.068
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0282 0.0819 0.0946
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0094 0.0244 0.0274
Plasmodium vivax aspartyl protease, putative 0.011 0.0294 0.1005
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0258 0.029
Entamoeba histolytica histone deacetylase, putative 0.0091 0.0235 0.0794
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.003 0.0059
Schistosoma mansoni alpha glucosidase 0.0037 0.0069 0.0069
Echinococcus multilocularis calpain family protein 1, d 0.1573 0.4765 0.476
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0027 0.006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.003 0.0048 0.0122
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0015 0.0012
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0235 0.0676 0.1418
Brugia malayi Angiotensin-converting enzyme family protein 0.0606 0.1808 0.2102
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0065 0.0178
Trichomonas vaginalis calmodulin, putative 0.0127 0.0346 0.1079
Trypanosoma cruzi histone deacetylase, putative 0.0102 0.0269 0.0303
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Schistosoma mansoni hypothetical protein 0.0094 0.0244 0.0274
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0089
Toxoplasma gondii calmodulin CAM1 0.013 0.0353 0.0729
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.001 0.0001
Echinococcus granulosus cpg binding protein 0.0031 0.0052 0.0049
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.003 0.0059
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0046
Trypanosoma cruzi cytochrome P450, putative 0.0044 0.0089 0.0093
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0046
Loa Loa (eye worm) hypothetical protein 0.0137 0.0375 0.0428
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0065 0.0178
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.003 0.0024
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0169 0.0186
Echinococcus multilocularis calpain 7 (C02 family) 0.0802 0.2408 0.2401
Entamoeba histolytica prolyl oligopeptidase family protein 0.0201 0.057 0.1979
Onchocerca volvulus 0.003 0.0049 0.0103
Echinococcus multilocularis enteropeptidase 0.0094 0.0244 0.0235
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Loa Loa (eye worm) hypothetical protein 0.1338 0.4045 0.4717
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.003 0.0105
Loa Loa (eye worm) hypothetical protein 0.1904 0.5778 0.6742
Leishmania major hypothetical protein, conserved 0.013 0.0353 0.0729
Toxoplasma gondii aspartyl protease ASP1 0.003 0.0048 0.0081
Plasmodium falciparum importin beta, putative 0.003 0.0049 0.014
Trypanosoma cruzi cysteine peptidase, putative 0.0944 0.2841 0.3309
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0088 0.0275
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0802 0.2408 0.5107
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0258 0.0529
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0158 0.0174
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0086 0.0076
Brugia malayi prolyl oligopeptidase family protein 0.0338 0.0989 0.1145
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0338 0.0989 0.2086
Plasmodium falciparum cysteine proteinase falcipain 1 0.0525 0.156 0.5478
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0338 0.0989 0.098
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.01 0.0105
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0086 0.0089
Onchocerca volvulus 0.0065 0.0155 0.033
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0101 0.0194
Plasmodium vivax aspartyl protease, putative 0.003 0.0048 0.0138
Trypanosoma cruzi cysteine proteinase, putative 0.0525 0.156 0.1812
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0239 0.0687 0.2175
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0012 0.0003
Brugia malayi Importin beta-1 subunit 0.003 0.0049 0.0045
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0089
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0286 0.0829 0.0959
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0112 0.0299 0.0337
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0299 0.1513
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0189 0.0382
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0127 0.0346 0.1079
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0026 0.0034
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0018 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.007 0.0171 0.019
Brugia malayi prolyl oligopeptidase family protein 0.0201 0.057 0.0655
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.003 0.011
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0037 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0007
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0088 0.0091
Onchocerca volvulus 0.0944 0.2841 0.6037
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0086 0.0243
Onchocerca volvulus 0.01 0.0261 0.0555
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0065 0.0065
Giardia lamblia Cathepsin L precursor 0.0239 0.0687 0.2175
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0235 0.0722
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0023 0.0013
Loa Loa (eye worm) cytochrome P450 0.0024 0.003 0.0025
Brugia malayi hypothetical protein 0.0065 0.0155 0.017
Schistosoma mansoni centrin 0.0127 0.0346 0.0393
Loa Loa (eye worm) hypothetical protein 0.0127 0.0346 0.0394
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0155 0.0171
Brugia malayi calpain family protein 1 0.214 0.6498 0.7583
Entamoeba histolytica proteasome subunit beta type 1, putative 0.007 0.0169 0.0561
Loa Loa (eye worm) hypothetical protein 0.0103 0.0271 0.0306
Toxoplasma gondii peptidase family M13 protein 0.0093 0.0241 0.0491
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.2803
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0189 0.018
Brugia malayi Muscleblind-like protein 0.0294 0.0855 0.0987
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.007 0.0171 0.019
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0029 0.0106
Echinococcus multilocularis proteasome (prosome, macropain) 0.009 0.023 0.022
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.0239 0.0687 0.0793
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0201 0.057 0.0655
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0094 0.0244 0.0235
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0086 0.0088
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Plasmodium falciparum cysteine repeat modular protein 1 0.0047 0.0099 0.0319
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0088 0.025
Loa Loa (eye worm) MH2 domain-containing protein 0.0136 0.0373 0.0425
Leishmania major histone deacetylase, putative 0.0102 0.0269 0.0552
Loa Loa (eye worm) histone deacetylase 0.0102 0.0269 0.0304
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.003 0.011
Toxoplasma gondii aspartyl protease 0.003 0.0048 0.0081
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.001 0.0001
Onchocerca volvulus 0.003 0.0048 0.0102
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2267 0.6887 0.8038
Loa Loa (eye worm) hypothetical protein 0.0658 0.1968 0.2289
Onchocerca volvulus 0.0741 0.2221 0.4718
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0023 0.0015
Mycobacterium tuberculosis Conserved protein 0.0036 0.0065 0.0145
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0127 0.0346 0.0336
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0031 0.0068
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0205 0.0227
Schistosoma mansoni calcium binding atopy-related autoantigen 0.013 0.0353 0.04
Trypanosoma brucei centrin-3 0.0131 0.0357 0.0738
Brugia malayi hypothetical protein 0.0094 0.0244 0.0274
Brugia malayi Trypsin family protein 0.0094 0.0244 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0086 0.0243
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0046
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0066 0.0119
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0101 0.0292
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0065 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0007
Loa Loa (eye worm) calpain family protein 1 0.1573 0.4765 0.5558
Schistosoma mansoni cathepsin F (C01 family) 0.0658 0.1968 0.2288
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0031 0.0068
Loa Loa (eye worm) hypothetical protein 0.0069 0.0166 0.0184
Brugia malayi follicle stimulating hormone receptor 0.0282 0.0819 0.0945
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0802 0.2408 0.2803
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0086 0.0088
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0083
Brugia malayi TAR-binding protein 0.0067 0.016 0.0175
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0086 0.0088
Schistosoma mansoni hypothetical protein 0.0247 0.0712 0.082
Echinococcus multilocularis caspase 0.0018 0.0012 0.0002
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0086 0.0076
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0026 0.0089
Giardia lamblia Cathepsin L precursor 0.0239 0.0687 0.2175
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0239 0.0687 0.2395
Toxoplasma gondii cathepsin CPL 0.0944 0.2841 0.6028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0239 0.0687 0.0792
Echinococcus granulosus calumenin 0.013 0.0353 0.04
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0023 0.0015
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0127 0.0346 0.0393
Echinococcus multilocularis caspase 2 0.0131 0.0355 0.0346
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0091 0.0235 0.0264
Schistosoma mansoni hypothetical protein 0.0034 0.0061 0.006
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.0676 0.2139
Loa Loa (eye worm) hypothetical protein 0.0093 0.0241 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0023 0.0015
Giardia lamblia Cathepsin B precursor 0.1036 0.3124 1
Onchocerca volvulus Prolyl endopeptidase homolog 0.1554 0.4706 1
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0236 0.0678 0.1422
Giardia lamblia Cathepsin L precursor 0.0239 0.0687 0.2175
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0086 0.0088
Brugia malayi hypothetical protein 0.0489 0.1451 0.1684
Trichomonas vaginalis calpain, putative 0.0235 0.0676 0.2139
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.009 0.023 0.0258
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0018 0.001 0.0001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.0824 0.2875
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.003 0.011
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.003 0.0059
Loa Loa (eye worm) hypothetical protein 0.0239 0.0687 0.0793
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0023 0.0015
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0239 0.0687 0.2175
Echinococcus granulosus caspase 8 0.0018 0.0012 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0243 0.0497
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.038 0.0915
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.0057
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0094 0.0244 0.0274
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0944 0.2841 0.331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0658 0.1968 0.6288
Brugia malayi nuclear hormone receptor 0.0022 0.0023 0.0015
Onchocerca volvulus 0.0096 0.025 0.0532
Mycobacterium ulcerans hypothetical protein 0.0036 0.0065 0.0295
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.001 0.0001
Echinococcus multilocularis cysteine protease 0.0944 0.2841 0.2834
Schistosoma mansoni hypothetical protein 0.0047 0.0099 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0239 0.0687 0.2175
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0239 0.0687 0.2395
Schistosoma mansoni cathepsin S (C01 family) 0.0239 0.0687 0.0792
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0027 0.0093
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Echinococcus multilocularis peroxidasin 0.0065 0.0155 0.0145
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0692 0.2073 0.2411
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0127 0.0346 0.1187
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0066
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0127 0.0346 0.0393
Trypanosoma cruzi major cysteine proteinase, putative 0.0239 0.0687 0.0792
Loa Loa (eye worm) histone deacetylase 1 0.0091 0.0235 0.0264
Echinococcus multilocularis microtubule associated protein 2 0.149 0.4511 0.4505
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.003 0.011
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0018 0.001 0.0001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0235 0.0676 0.0778
Brugia malayi carbohydrate phosphorylase 0.0109 0.029 0.0328
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1353 0.4092 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0171 0.019
Echinococcus multilocularis Mastin 0.0094 0.0244 0.0235
Trypanosoma cruzi oligopeptidase b 0.0643 0.1923 0.2236
Trypanosoma cruzi major cysteine proteinase, putative 0.0343 0.1005 0.1163
Brugia malayi beta-lactamase family protein 0.0036 0.0065 0.0065
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0003
Loa Loa (eye worm) calpain 0.0802 0.2408 0.2804
Toxoplasma gondii microneme protein, putative 0.003 0.0049 0.0083
Leishmania major histone deacetylase, putative 0.0102 0.0269 0.0552
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Brugia malayi cathepsin Z-like cysteine proteinase 0.0239 0.0687 0.0792
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0075 0.0065
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0075 0.0076
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0037 0.0097
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.003 0.0059
Brugia malayi hypothetical protein 0.0072 0.0177 0.0195
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0086 0.0088
Echinococcus multilocularis programmed cell death protein 0.0131 0.0357 0.0347
Loa Loa (eye worm) trypsin family protein 0.0094 0.0244 0.0275
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.038 0.1935
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0235 0.0676 0.0778
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0065 0.0065
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0049 0.0083
Echinococcus granulosus Mastin 0.0094 0.0244 0.0274
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0104 0.0276 0.0312
Plasmodium falciparum serine repeat antigen 8 0.0239 0.0687 0.2395
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0065 0.0145
Brugia malayi Kringle domain containing protein 0.0047 0.0099 0.0104
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.003 0.011
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1036 0.3124 0.364
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0239 0.0687 0.2395
Schistosoma mansoni cytochrome P450 0.0024 0.003 0.0024
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.003 0.011
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0027 0.0093
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0023 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0023 0.0015
Toxoplasma gondii microneme protein MIC17A 0.003 0.0049 0.0083
Trypanosoma cruzi histone deacetylase 1, putative 0.0091 0.0235 0.0263
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0069 0.019
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0189 0.0943
Giardia lamblia Histone deacetylase 0.0091 0.0235 0.0722
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0802 0.2408 0.2803
Brugia malayi Papain family cysteine protease containing protein 0.0239 0.0687 0.0792
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.007 0.0171 0.019
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.009 0.023 0.0547
Brugia malayi Trypsin-like protease protein 5 0.0094 0.0244 0.0274
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0029 0.0106
Leishmania major hypothetical protein, conserved 0.0235 0.0676 0.1418
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0075 0.0209
Brugia malayi beta-lactamase 0.0036 0.0065 0.0065
Trypanosoma cruzi centrin-3 0.0131 0.0357 0.0405
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1554 0.4706 0.5489
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0643 0.1923 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0023 0.0049
Entamoeba histolytica cysteine proteinase 2 0.0525 0.156 0.5477
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0065
Onchocerca volvulus 0.0036 0.0065 0.0139
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0525 0.156 0.1812
Plasmodium vivax proteasome subunit beta type-4, putative 0.0018 0.001 0.0003
Mycobacterium ulcerans proteasome PrcB 0.009 0.023 0.1154
Loa Loa (eye worm) CYP4Cod1 0.0044 0.0089 0.0094
Echinococcus granulosus apoptotic protease activating factor 1 0.0112 0.0299 0.0338
Echinococcus granulosus cathepsin b 0.2816 0.8566 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0109 0.0518
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0075 0.0076
Trypanosoma brucei calmodulin, putative 0.0127 0.0346 0.0715
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0018 0.0012 0.0003
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0084 0.0087
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Toxoplasma gondii histone deacetylase HDAC4 0.0044 0.009 0.0172
Toxoplasma gondii hypothetical protein 0.003 0.0049 0.0083
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0024
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0155 0.033
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0015 0.0006
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0692 0.2073 0.4404
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0231 0.0258
Loa Loa (eye worm) cathepsin B 0.1036 0.3124 0.364
Entamoeba histolytica cysteine proteinase 1, putative 0.0525 0.156 0.5477
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0643 0.1923 1
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0018 0.001 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0247 0.0712 0.1726
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.0676 0.2139
Echinococcus multilocularis transmembrane protease serine 3 0.0094 0.0244 0.0235
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0086 0.0088
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0651 0.1945 0.2263
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0015 0.0006
Plasmodium falciparum peptidase, putative 0.0201 0.057 0.1981
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0084 0.0239
Onchocerca volvulus 0.0022 0.0023 0.0049
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.003 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.0687 0.2175
Trypanosoma brucei cysteine peptidase, putative 0.0235 0.0676 0.1418
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0069 0.0069
Onchocerca volvulus 0.003 0.0047 0.0099
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0061 0.006
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0023 0.0015
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0101 0.0321
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.029 0.0901
Trichomonas vaginalis myosin light chain 1, putative 0.0127 0.0346 0.1079
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.003 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0084 0.0239
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0127 0.0346 0.0393
Schistosoma mansoni hypothetical protein 0.0074 0.0183 0.0202
Giardia lamblia Cysteine protease 0.0239 0.0687 0.2175
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0029 0.0041
Loa Loa (eye worm) hypothetical protein 0.0239 0.0687 0.0793
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0338 0.0989 0.2086
Entamoeba histolytica hypothetical protein 0.0239 0.0687 0.2392
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0944 0.2841 0.331
Schistosoma mansoni neuronal calcium sensor 0.0127 0.0346 0.0393
Toxoplasma gondii proteasome subunit beta type, putative 0.009 0.023 0.0468
Brugia malayi Papain family cysteine protease containing protein 0.0239 0.0687 0.0792
Brugia malayi Protein kinase domain containing protein 0.0047 0.0099 0.0104
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Echinococcus multilocularis calumenin 0.013 0.0353 0.0343
Trypanosoma cruzi I/6 autoantigen, putative 0.0127 0.0346 0.0393
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0054 0.0232
Echinococcus granulosus geminin 0.0518 0.1541 0.179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0065 0.0145
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0088 0.0091
Trypanosoma cruzi histone deacetylase 1, putative 0.0091 0.0235 0.0263
Entamoeba histolytica cysteine proteinase, putative 0.0944 0.2841 1
Giardia lamblia Cathepsin L precursor 0.0239 0.0687 0.2175
Plasmodium falciparum serine repeat antigen 5 0.0239 0.0687 0.2395
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0018 0.001 0.0001
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0239 0.0687 0.2395
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0261 0.0294
Schistosoma mansoni hypothetical protein 0.01 0.0261 0.0294
Loa Loa (eye worm) hypothetical protein 0.0094 0.0243 0.0274
Plasmodium vivax proteasome subunit beta type-6, putative 0.0018 0.001 0.0003
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0127 0.0346 0.1079
Entamoeba histolytica cysteine protease, putative 0.0239 0.0687 0.2392
Entamoeba histolytica hypothetical protein, conserved 0.0201 0.057 0.1979
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0235 0.0722
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0027 0.0036
Schistosoma mansoni survival motor neuron protein 0.01 0.0261 0.0294
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0281 0.0817 0.0808
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0029 0.0019
Echinococcus granulosus Transglutaminase 0.0247 0.0712 0.082
Schistosoma mansoni hypothetical protein 0.0112 0.0299 0.0338
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0155 0.0171
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0944 0.2841 1
Schistosoma mansoni calpain-2 (C02 family) 0.0235 0.0676 0.0778
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.003 0.0059
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.003 0.0024
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0023 0.0015
Echinococcus granulosus tissue type plasminogen activator 0.0047 0.0099 0.0104
Plasmodium vivax SET domain protein, putative 0.0094 0.0243 0.0827
Onchocerca volvulus 0.0944 0.2841 0.6037
Trypanosoma brucei antigen, putative 0.0802 0.2408 0.5107
Trichomonas vaginalis calcineurin B subunit, putative 0.013 0.0353 0.11
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0012 0.0003
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2816 0.8566 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0025 0.0018
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0026 0.0084
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Schistosoma mansoni centrin-related 0.0127 0.0346 0.0393
Loa Loa (eye worm) hypothetical protein 0.007 0.0171 0.019
Leishmania major cysteine peptidase A (CPA) 0.0944 0.2841 0.6028
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0101 0.0106
Giardia lamblia Hypothetical protein 0.0239 0.0687 0.2175
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Echinococcus multilocularis histone deacetylase 0.0102 0.0269 0.0259
Entamoeba histolytica calpain large subunit domain III containing protein 0.0567 0.1688 0.5929
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0065 0.0056
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0018 0.001 0.0003
Echinococcus multilocularis calcium uptake protein 1 0.013 0.0353 0.0343
Giardia lamblia Cysteine protease 0.0239 0.0687 0.2175
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0205 0.0227
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0119
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0465 0.0455
Plasmodium vivax plasmepsin V, putative 0.003 0.0048 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Onchocerca volvulus 0.003 0.0049 0.0103
Echinococcus granulosus histone deacetylase 6 0.0102 0.0269 0.0303
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0177 0.0195
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0066
Mycobacterium leprae probable zinc metalloprotease 0.0093 0.0241 0.1205
Schistosoma mansoni hypothetical protein 0.0127 0.0346 0.0393
Mycobacterium tuberculosis Probable peptidase 0.0643 0.1923 0.4691
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0189 0.0637
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Plasmodium falciparum serine repeat antigen 7 0.0239 0.0687 0.2395
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0235 0.0676 0.0778
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0525 0.156 0.3301
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0024 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0015 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0239 0.0687 0.2175
Entamoeba histolytica cysteine proteinase, putative 0.0658 0.1968 0.6916
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Entamoeba histolytica cysteine proteinase, putative 0.0525 0.156 0.5477
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0024 0.0017
Echinococcus granulosus gamma secretase subunit aph 1 0.0254 0.0731 0.0843
Loa Loa (eye worm) TAR-binding protein 0.0067 0.016 0.0176
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Entamoeba histolytica cysteine proteinase, putative 0.0525 0.156 0.5477
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0061 0.0051
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0101 0.0325
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.003 0.011
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0049 0.0083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2816 0.8566 1
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0086 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0235 0.0676 0.2139
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0069 0.0126
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0061 0.0051
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0239 0.0687 0.2395
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0239 0.0687 0.2395
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0525 0.156 0.4979
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0027 0.0089
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0089 0.0094
Giardia lamblia Cathepsin B precursor 0.0239 0.0687 0.2175
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0069 0.0069
Trypanosoma cruzi cysteine proteinase, putative 0.0525 0.156 0.1812
Loa Loa (eye worm) calpain family protein 1 0.214 0.6498 0.7583
Loa Loa (eye worm) hypothetical protein 0.0155 0.0429 0.0491
Leishmania major GTP-binding protein, putative 0.0022 0.0024 0.0031
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0065 0.0145
Schistosoma mansoni importin beta-1 0.003 0.0049 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0086 0.0088
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Trypanosoma brucei Component of motile flagella 41 0.0127 0.0346 0.0715
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0086 0.0089
Trichomonas vaginalis ran, putative 0.0022 0.0024 0.0046
Leishmania major calcineurin B subunit, putative 0.0127 0.0346 0.0715
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0084 0.0087
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0066 0.0056
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.0088
Echinococcus multilocularis histone deacetylase 8 0.0044 0.009 0.0081
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0027 0.0093
Trypanosoma brucei metacaspase 0.0018 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0069 0.0166 0.0184
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0094 0.0244 0.0274
Brugia malayi calpain 7 0.0802 0.2408 0.2803
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0029 0.0057
Brugia malayi Pre-SET motif family protein 0.0094 0.0243 0.0273
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0066
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0338 0.0989 0.1145
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0049 0.0083
Loa Loa (eye worm) hypothetical protein 0.0167 0.0466 0.0534
Echinococcus multilocularis histone deacetylase 7 0.0102 0.0269 0.0259
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0065 0.0178
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0026 0.006
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.007 0.0169 0.0186
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0239 0.0687 0.0792
Loa Loa (eye worm) hypothetical protein 0.0239 0.0687 0.0793
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0155 0.0429 0.042
Onchocerca volvulus 0.003 0.0049 0.0103
Onchocerca volvulus 0.0127 0.0346 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0239 0.0687 0.2392
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.003 0.0043
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0027 0.0036
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0065
Toxoplasma gondii kringle domain-containing protein 0.0047 0.0099 0.019
Loa Loa (eye worm) histone deacetylase 3 0.0091 0.0235 0.0264
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0088 0.0279
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0089
Loa Loa (eye worm) hypothetical protein 0.0093 0.0241 0.0271
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.023 0.0706
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0944 0.2841 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Loa Loa (eye worm) hypothetical protein 0.0058 0.0135 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0075 0.0209
Onchocerca volvulus 0.0042 0.0084 0.0179
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0177 0.0167
Schistosoma mansoni cathepsin F (C01 family) 0.0944 0.2841 0.3309
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0362 0.1064 0.1232
Toxoplasma gondii histone deacetylase HDAC5 0.0044 0.0091 0.0173
Trypanosoma brucei hypothetical protein, conserved 0.0208 0.0592 0.1239
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0023 0.0015
Echinococcus granulosus histone deacetylase 1 0.0091 0.0235 0.0263
Mycobacterium tuberculosis Conserved protein 0.0247 0.0712 0.1726
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0239 0.0687 0.0793
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0687 0.2175
Trypanosoma cruzi oligopeptidase b 0.0643 0.1923 0.2236
Plasmodium falciparum serine repeat antigen 6 0.0239 0.0687 0.2395
Toxoplasma gondii centrin, putative 0.0127 0.0346 0.0715
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0065 0.0065
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0239 0.0687 0.2395
Giardia lamblia Encystation-specific protease 0.0239 0.0687 0.2175
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0525 0.156 0.1812
Plasmodium vivax vivapain-1 0.0525 0.156 0.5478
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0027 0.0093
Trichomonas vaginalis calmodulin, putative 0.0127 0.0346 0.1079
Toxoplasma gondii microneme protein MIC17B 0.003 0.0049 0.0083
Giardia lamblia Cathepsin L precursor 0.0239 0.0687 0.2175
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Echinococcus granulosus proteasome prosome macropain subunit beta 0.007 0.0169 0.0186
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0024
Trypanosoma brucei calpain-like protein, putative 0.0802 0.2408 0.5107
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0027 0.0036
Trichomonas vaginalis calcium binding protein, putative 0.0127 0.0346 0.1079
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0189 0.021
Brugia malayi hypothetical protein 0.003 0.0048 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Echinococcus multilocularis survival motor neuron protein 1 0.0489 0.1451 0.1443
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0069 0.007
Brugia malayi EF hand family protein 0.0127 0.0346 0.0393
Toxoplasma gondii troponin c, isotype gamma, putative 0.0127 0.0346 0.0715
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0086 0.0243
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0027 0.0089
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0024 0.0018
Echinococcus multilocularis programmed cell death protein 0.0131 0.0357 0.0347
Chlamydia trachomatis glycogen phosphorylase 0.0109 0.029 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0024
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0018 0.001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Plasmodium vivax hypothetical protein, conserved 0.0201 0.057 0.1981
Brugia malayi hypothetical protein 0.0112 0.0299 0.0338
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0525 0.156 0.1812
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0086 0.0089
Trichomonas vaginalis calmodulin, putative 0.0127 0.0346 0.1079
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0323 0.0944 0.1093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Toxoplasma gondii exonuclease III APE 0.0019 0.0015 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0023 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0023 0.0015
Giardia lamblia Cathepsin B precursor 0.1036 0.3124 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0244 0.0275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0643 0.1923 0.4074
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0084 0.0087
Onchocerca volvulus 0.003 0.0049 0.0103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0281 0.0817 0.0943
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0109 0.0252
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0047 0.0099 0.0319
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0086 0.0076
Loa Loa (eye worm) hypothetical protein 0.0235 0.0676 0.0779
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0274
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.009 0.023 0.0257
Toxoplasma gondii histone deacetylase HDAC2 0.0091 0.0235 0.0479
Echinococcus multilocularis calbindin 32 0.013 0.0353 0.0343
Trypanosoma cruzi cysteine peptidase, putative 0.1047 0.3159 0.368
Trypanosoma cruzi cysteine peptidase, putative 0.0525 0.156 0.1812
Brugia malayi histone deacetylase 1 (HD1) 0.0091 0.0235 0.0263
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Brugia malayi CXXC zinc finger family protein 0.003 0.0047 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Giardia lamblia Hypothetical protein 0.0239 0.0687 0.2175
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0155 0.017
Schistosoma mansoni hypothetical protein 0.0155 0.0429 0.049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Trypanosoma brucei calpain-like protein, putative 0.0802 0.2408 0.5107
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0086 0.0088
Plasmodium falciparum plasmepsin II 0.003 0.0048 0.0138
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0075 0.0065
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0201 0.057 0.1979
Brugia malayi Cathepsin L-like precursor 0.0658 0.1968 0.2288
Giardia lamblia Cathepsin L precursor 0.0239 0.0687 0.2175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.0687 0.2175
Leishmania major cathepsin L-like protease 0.0944 0.2841 0.6028
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0065 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0065 0.0178
Entamoeba histolytica hypothetical protein 0.0072 0.0177 0.0588
Onchocerca volvulus 0.003 0.0049 0.0103
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0189 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0084 0.0239
Schistosoma mansoni calmodulin related calcium binding protein 0.0127 0.0346 0.0393
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0692 0.2073 0.2065
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.003 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0069 0.0069
Plasmodium falciparum proteasome subunit beta type-4 0.0018 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0239 0.0687 0.2175
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0166 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.003 0.0059
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.003 0.011
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0239 0.0687 0.0793
Echinococcus multilocularis calpain A 0.2269 0.6894 0.6891
Trypanosoma cruzi hypothetical protein, conserved 0.0201 0.057 0.0655
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0069 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0086 0.0088
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.003 0.0048 0.0081
Toxoplasma gondii hypothetical protein 0.0026 0.0037 0.0057
Leishmania major centrin, putative 0.0127 0.0346 0.0715
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.013 0.0353 0.04
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0086 0.0088
Entamoeba histolytica calmodulin, putative 0.0127 0.0346 0.1187
Plasmodium vivax unspecified product 0.0525 0.156 0.5478
Trypanosoma brucei prolyl endopeptidase 0.1554 0.4706 1
Trypanosoma brucei mitochondrial calcium uptake 1 0.0127 0.0346 0.0715
Loa Loa (eye worm) hypothetical protein 0.0094 0.0244 0.0275
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0086 0.0076
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0023 0.0015
Echinococcus granulosus proteasome prosome macropain 0.009 0.023 0.0257
Trypanosoma cruzi I/6 autoantigen, putative 0.0127 0.0346 0.0393
Entamoeba histolytica hypothetical protein 0.0072 0.0177 0.0588
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0183 0.0202
Toxoplasma gondii prolyl endopeptidase 0.1554 0.4706 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0069 0.019
Echinococcus multilocularis tar DNA binding protein 0.0067 0.016 0.015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0023 0.0013
Schistosoma mansoni neuronal calcium sensor 0.0127 0.0346 0.0393
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0066 0.3113
Loa Loa (eye worm) ctsf protein 0.0944 0.2841 0.331
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0066 0.0179
Brugia malayi Pepsin A precursor 0.003 0.0048 0.0045
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.0824 1
Brugia malayi Cytochrome P450 family protein 0.0024 0.003 0.0024
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.5107
Loa Loa (eye worm) hypothetical protein 0.007 0.0171 0.019
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Loa Loa (eye worm) blistered cuticle protein 3 0.0065 0.0155 0.0171
Trypanosoma brucei C-8 sterol isomerase, putative 0.0362 0.1064 0.2245
Brugia malayi fibroinase precursor 0.0239 0.0687 0.0792
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.003 0.0059
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0235 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0007
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.003 0.011
Loa Loa (eye worm) aspartyl protease 6 0.003 0.0048 0.0046
Schistosoma mansoni cathepsin s 0.0286 0.0829 0.0958
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0243 0.0273
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0031 0.0068
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0075 0.0076
Entamoeba histolytica cysteine proteinase, putative 0.0944 0.2841 1
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0018 0.001 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0525 0.156 0.5477
Brugia malayi Cathepsin L-like precursor 0.0944 0.2841 0.3309
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0015 0.0006
Toxoplasma gondii histone deacetylase HDAC1 0.0102 0.0269 0.0552
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0239 0.0687 0.2175
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0088 0.0279
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0355 0.1805
Echinococcus granulosus importin subunit beta 1 0.003 0.0049 0.0045
Giardia lamblia Cathepsin B precursor 0.0239 0.0687 0.2175
Onchocerca volvulus Peroxidase homolog 0.0065 0.0155 0.033
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0066
Plasmodium falciparum histone deacetylase 2 0.0102 0.0269 0.0918
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Schistosoma mansoni hypothetical protein 0.0518 0.1541 0.179
Brugia malayi hypothetical protein 0.0042 0.0086 0.0088
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0018 0.001 0.0003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0281 0.0817 0.0944
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0004
Onchocerca volvulus Cathepsin F homolog 0.0944 0.2841 0.6037
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.003 0.011
Echinococcus granulosus cathepsin L 0.0525 0.156 0.1812
Brugia malayi histone deacetylase 11 0.0044 0.009 0.0094
Brugia malayi calpain family protein 1 0.214 0.6498 0.7583
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0239 0.0687 0.2175
Leishmania major cytochrome p450-like protein 0.0024 0.003 0.0043
Schistosoma mansoni glycogen phosphorylase 0.0109 0.029 0.0328
Loa Loa (eye worm) prolyl oligopeptidase 0.0201 0.057 0.0656
Brugia malayi Thioredoxin family protein 0.0247 0.0712 0.082
Trichomonas vaginalis peptide N-glycanase, putative 0.0247 0.0712 0.2253
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.003 0.011
Echinococcus multilocularis histone deacetylase 3 0.0091 0.0235 0.0225
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0155 0.017
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0024 0.0017
Plasmodium falciparum plasmepsin III 0.003 0.0048 0.0138
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0026 0.0034
Trypanosoma brucei I/6 autoantigen 0.0127 0.0346 0.0715
Trichomonas vaginalis calmodulin, putative 0.0127 0.0346 0.1079
Plasmodium vivax histone deacetylase, putative 0.0102 0.0269 0.0918
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0086 0.0089
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.0676 0.2139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0525 0.156 0.4979
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.0465 0.0533
Onchocerca volvulus 0.0127 0.0346 0.0735
Plasmodium vivax histone deacetylase, putative 0.0044 0.009 0.0288
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0101 0.0194
Brugia malayi Papain family cysteine protease containing protein 0.0944 0.2841 0.3309
Loa Loa (eye worm) programmed cell death protein 6 0.013 0.0353 0.0401
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0127 0.0346 0.0393
Plasmodium falciparum metacaspase-like protein 0.0018 0.0012 0.0011
Entamoeba histolytica cysteine protease, putative 0.0239 0.0687 0.2392
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0069 0.019
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0018 0.001 0.0003
Schistosoma mansoni histone deacetylase 1 2 3 0.0044 0.009 0.0094
Giardia lamblia Serine peptidase, putative 0.0042 0.0084 0.0239
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0239 0.0687 0.0792
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trypanosoma cruzi cytochrome P450, putative 0.0044 0.0089 0.0093
Trypanosoma brucei protein I/6 0.0127 0.0346 0.0715
Trypanosoma brucei metacaspase MCA3 0.0018 0.0012 0.0005
Giardia lamblia Cathepsin B precursor 0.0239 0.0687 0.2175
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0075 0.0076
Echinococcus multilocularis geminin 0.0518 0.1541 0.1533
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0084 0.0239
Echinococcus granulosus neuronal calcium sensor 0.0127 0.0346 0.0393
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.0654 0.1586
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Leishmania major calmodulin-like protein 0.0127 0.0346 0.0715
Leishmania major cytochrome p450-like protein 0.0024 0.003 0.0043
Echinococcus granulosus centrin 2 0.0127 0.0346 0.0393
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.214 0.6498 0.7583
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0099 0.0104
Leishmania major cathepsin L-like protease 0.0944 0.2841 0.6028
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0802 0.2408 0.2803
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0243 0.0273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Toxoplasma gondii centrin 0.0127 0.0346 0.0715
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0023 0.0015
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.0448 0.0513
Giardia lamblia Hypothetical protein 0.0247 0.0712 0.2253
Brugia malayi calpain 5 0.0235 0.0676 0.0778
Trypanosoma brucei Calpain-like protein 1.2 0.0235 0.0676 0.1418
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0069 0.0059
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0189 0.0637
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0066 0.0297
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0021
Trypanosoma brucei calmodulin, putative 0.013 0.0353 0.0729
Loa Loa (eye worm) hypothetical protein 0.0094 0.0244 0.0275
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0083
Loa Loa (eye worm) hypothetical protein 0.0658 0.1968 0.2289
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0235 0.0722
Trypanosoma cruzi centrin, putative 0.0131 0.0357 0.0405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0034 0.0061 0.006
Toxoplasma gondii cathepsin B 0.1036 0.3124 0.6631
Schistosoma mansoni calpain-7 (C02 family) 0.0808 0.2426 0.2824
Mycobacterium ulcerans hypothetical protein 0.0023 0.0027 0.0093
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Trypanosoma brucei metacaspase 5, putative 0.0018 0.0012 0.0005
Schistosoma mansoni gamma-secretase subunit aph-1 0.0254 0.0731 0.0843
Onchocerca volvulus 0.0247 0.0712 0.1512
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0525 0.156 0.3301
Loa Loa (eye worm) hypothetical protein 0.0076 0.0189 0.0211
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0083
Leishmania major calmodulin-like protein 0.0127 0.0346 0.0715
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Onchocerca volvulus 0.003 0.0048 0.0102
Echinococcus multilocularis endothelin converting enzyme 1 0.0093 0.0241 0.0231
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.003 0.0059
Mycobacterium leprae Conserved hypothetical protein 0.0247 0.0712 0.3667
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0047 0.01 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0007
Trypanosoma brucei calpain-like protein, putative 0.0802 0.2408 0.5107
Brugia malayi Papain family cysteine protease containing protein 0.0239 0.0687 0.0792
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0083
Plasmodium vivax vivapain-3 0.0525 0.156 0.5478
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0084 0.0087
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0024 0.0046
Brugia malayi Peroxidasin 0.0065 0.0155 0.017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0239 0.0687 0.0792
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0101 0.0321
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0083
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0075 0.0076
Loa Loa (eye worm) hypothetical protein 0.0294 0.0855 0.0988
Schistosoma mansoni calpain-7 (C02 family) 0.0808 0.2426 0.2824
Plasmodium falciparum proteasome subunit beta type-5 0.009 0.023 0.078
Trypanosoma cruzi conserved protein 0.0235 0.0676 0.0778
Trypanosoma cruzi cruzipain precursor, putative 0.0286 0.0829 0.0958
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.003 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0687 0.2175
Echinococcus multilocularis apoptotic protease activating factor 1 0.0112 0.0299 0.029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0089
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0201 0.057 0.1193
Brugia malayi cathepsin Z-like cysteine proteinase 0.0239 0.0687 0.0792
Schistosoma mansoni hypothetical protein 0.0034 0.0061 0.006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Trypanosoma brucei histone deacetylase 4 0.0102 0.0269 0.0552
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0239 0.0687 0.2395
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0075 0.0139
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0086 0.0088
Toxoplasma gondii ABC1 family protein 0.0036 0.0065 0.0118
Onchocerca volvulus 0.0944 0.2841 0.6037
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0015 0.0022
Giardia lamblia Alanyl dipeptidyl peptidase 0.0201 0.057 0.1799
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.2803
Echinococcus multilocularis EF hand domain containing family member A2 0.0127 0.0346 0.0336
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0362 0.1064 0.1232
Plasmodium falciparum serine repeat antigen 2 0.0239 0.0687 0.2395
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0169 0.0186
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0046
Plasmodium vivax proteasome subunit beta type-7, putative 0.0018 0.001 0.0003
Entamoeba histolytica calcium binding family protein 0.0127 0.0346 0.1187
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0023 0.0015
Trypanosoma brucei kinesin, putative 0.0567 0.1688 0.3574
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0015 0.0007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0088 0.0078
Onchocerca volvulus 0.0094 0.0244 0.0519
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0024
Trypanosoma brucei oligopeptidase b 0.0643 0.1923 0.4074
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0029 0.0062
Giardia lamblia Proteasome subunit beta type 5 precursor 0.009 0.023 0.0706
Mycobacterium tuberculosis Conserved protein 0.0036 0.0065 0.0145
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1554 0.4706 0.5489
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.029 0.0991
Onchocerca volvulus 0.0081 0.0205 0.0435
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0015 0.0006
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0093 0.0241 0.0269
Giardia lamblia Alanyl dipeptidyl peptidase 0.0201 0.057 0.1799
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0084 0.0262
Schistosoma mansoni calmodulin 0.0127 0.0346 0.0393
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0189 1
Trypanosoma brucei calpain, putative 0.0235 0.0676 0.1418
Leishmania major calmodulin, putative 0.0127 0.0346 0.0715
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0023 0.0015
Leishmania major cathepsin L-like protease 0.0944 0.2841 0.6028
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0258 0.029
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0086 0.0076
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0093 0.0241 0.0574
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0029 0.0023
Loa Loa (eye worm) hypothetical protein 0.0286 0.0829 0.0959
Entamoeba histolytica hypothetical protein, conserved 0.013 0.0353 0.121
Toxoplasma gondii preprocathepsin c precursor, putative 0.0239 0.0687 0.1442
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2267 0.6887 0.8038
Echinococcus granulosus expressed protein 0.0824 0.2475 0.2881
Plasmodium vivax proteasome subunit beta type-1, putative 0.007 0.0169 0.0564
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0235 0.0676 0.0778
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0018 0.001 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Mycobacterium tuberculosis Conserved protein 0.0036 0.0065 0.0145
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.0025 0.0018
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0018 0.001 0.0003
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0018 0.001 0.0003
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0189 0.6411
Loa Loa (eye worm) hypothetical protein 0.0046 0.0097 0.0103
Echinococcus multilocularis cpg binding protein 0.0031 0.0052 0.0042
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Brugia malayi histone deacetylase 3 (HD3) 0.0091 0.0235 0.0263
Echinococcus granulosus EF HAND 1 calcium binding site 0.0127 0.0346 0.0393
Plasmodium vivax unspecified product 0.0239 0.0687 0.2395
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0281 0.0817 0.0943
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Echinococcus multilocularis glycoprotein Antigen 5 0.0094 0.0244 0.0235
Trichomonas vaginalis calcium binding proteins, putative 0.0127 0.0346 0.1079
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0127 0.0346 0.0393
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0065 0.0178
Loa Loa (eye worm) calmodulin-like protein 0.0127 0.0346 0.0394
Loa Loa (eye worm) glycogen phosphorylase 0.0109 0.029 0.0329
Loa Loa (eye worm) hypothetical protein 0.003 0.0048 0.0046
Giardia lamblia Cysteine protease 0.0239 0.0687 0.2175
Echinococcus multilocularis calpain 5 0.0802 0.2408 0.2401
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0239 0.0687 0.2395
Schistosoma mansoni tar DNA-binding protein 0.0067 0.016 0.0175
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0288 0.0326
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Loa Loa (eye worm) hypothetical protein 0.003 0.0048 0.0046
Giardia lamblia Cathepsin L-like protease 0.0239 0.0687 0.2175
Trypanosoma brucei Metacaspase-4 0.0018 0.0012 0.0005
Brugia malayi calpain D 0.0235 0.0676 0.0778
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0243 0.0273
Entamoeba histolytica prolyl oligopeptidase family protein 0.0201 0.057 0.1979
Entamoeba histolytica cysteine proteinase, putative 0.0525 0.156 0.5477
Brugia malayi calcium-binding protein 0.0127 0.0346 0.0393
Schistosoma mansoni alpha-glucosidase 0.0143 0.0394 0.0449
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.0676 0.2139
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0049 0.0083
Loa Loa (eye worm) calpain D 0.0235 0.0676 0.0779
Trichomonas vaginalis calmodulin, putative 0.0127 0.0346 0.1079
Loa Loa (eye worm) calpain 5 0.0567 0.1688 0.1963
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0112 0.0299 0.0615
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0086 0.0088
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0027 0.002
Entamoeba histolytica hypothetical protein 0.0042 0.0086 0.0267
Plasmodium vivax proteasome subunit beta type-3, putative 0.0018 0.001 0.0003
Trypanosoma cruzi centrin, putative 0.0131 0.0357 0.0405
Schistosoma mansoni peroxidasin 0.0065 0.0155 0.017
Leishmania major C-8 sterol isomerase-like protein 0.0362 0.1064 0.2245
Echinococcus granulosus dnaJ subfamily B 0.0421 0.1244 0.1442
Entamoeba histolytica hypothetical protein 0.0025 0.0031 0.0075
Loa Loa (eye worm) hypothetical protein 0.0362 0.1064 0.1233
Plasmodium vivax serine-repeat antigen (SERA) 0.0239 0.0687 0.2395
Onchocerca volvulus Glycogen phosphorylase homolog 0.0109 0.029 0.0617
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0015 0.0017
Schistosoma mansoni cathepsin D (A01 family) 0.0124 0.0335 0.0379
Echinococcus granulosus cathepsin L cysteine proteinase 0.0944 0.2841 0.3309
Mycobacterium ulcerans putative transglutaminase-like protein 0.0247 0.0712 0.3671
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0239 0.0687 0.2175
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0065 0.0118
Schistosoma mansoni hypothetical protein 0.0072 0.0177 0.0195
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0177 0.0195
Leishmania major centrin, putative 0.0127 0.0346 0.0715
Trypanosoma cruzi histone deacetylase, putative 0.0044 0.009 0.0094
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Echinococcus multilocularis 0.0024 0.003 0.002
Echinococcus granulosus cathepsin b 0.2816 0.8566 1
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0018 0.0012 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Onchocerca volvulus Cathepsin L homolog 0.0239 0.0687 0.146
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.003 0.011
Onchocerca volvulus Cathepsin L homolog 0.0944 0.2841 0.6037
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0338 0.0989 0.2086
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.01 0.0105
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.0088
Trypanosoma brucei cysteine peptidase C (CPC) 0.1036 0.3124 0.6631
Brugia malayi Trypsin family protein 0.0094 0.0244 0.0274
Echinococcus granulosus EF hand domain containing family member A2 0.0127 0.0346 0.0393
Loa Loa (eye worm) RNA binding protein 0.0067 0.016 0.0176
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0189 0.2153
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Entamoeba histolytica protein kinase, putative 0.0567 0.1688 0.5929
Loa Loa (eye worm) hypothetical protein 0.214 0.6498 0.7583
Brugia malayi hypothetical protein 0.0167 0.0466 0.0533
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0338 0.0989 0.1145
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.003 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0084 0.0087
Echinococcus multilocularis snurportin 1 0.0323 0.0944 0.0935
Echinococcus granulosus calmodulin 0.0127 0.0346 0.0393
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0084 0.0239
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0018 0.001 0.0003
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0084 0.0087
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0643 0.1923 0.2236
Plasmodium vivax aspartyl protease, putative 0.011 0.0294 0.1005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1036 0.3124 0.364
Schistosoma mansoni cathepsin B (C01 family) 0.0239 0.0687 0.0792
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2816 0.8566 1
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0127 0.0346 0.0336
Echinococcus granulosus cathepsin L cysteine protease 0.0525 0.156 0.1812
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0155 0.0429 0.049
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0346 0.1079
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Schistosoma mansoni cathepsin D (A01 family) 0.0124 0.0335 0.0379
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0239 0.0687 0.2175
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0205 0.0227
Loa Loa (eye worm) hypothetical protein 0.1573 0.4765 0.5558
Echinococcus granulosus neurocalcin 0.0127 0.0346 0.0393
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0027 0.0093
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0018 0.001 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.003 0.0048 0.0081
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Mycobacterium ulcerans beta-lactamase 0.0036 0.0065 0.0295
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0086 0.0088
Plasmodium falciparum histone deacetylase, putative 0.0102 0.0269 0.0918
Loa Loa (eye worm) transcription factor SMAD2 0.0136 0.0373 0.0425
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0281 0.0817 0.0943
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0254 0.0731 0.0844
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0155 0.033
Echinococcus multilocularis cathepsin L 0.0525 0.156 0.1552
Schistosoma mansoni memapsin-2 (A01 family) 0.0476 0.1412 0.1639
Trypanosoma cruzi kinesin, putative 0.0567 0.1688 0.1962
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0018 0.001 0.0003
Onchocerca volvulus 0.003 0.0049 0.0103
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0065 0.0145
Brugia malayi Cathepsin L-like precursor 0.0944 0.2841 0.3309
Plasmodium falciparum plasmepsin VII 0.003 0.0048 0.0138
Schistosoma mansoni hypothetical protein 0.0235 0.0676 0.0778
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0239 0.0687 0.0792
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.0088
Mycobacterium ulcerans lipase LipD 0.0036 0.0065 0.0295
Brugia malayi cytochrome P450 0.0024 0.003 0.0024
Schistosoma mansoni histone deacetylase hda2 0.0109 0.0289 0.0326
Echinococcus multilocularis Transglutaminase 0.0247 0.0712 0.0702
Trichomonas vaginalis calmodulin-2, putative 0.0127 0.0346 0.1079
Leishmania major calmodulin, putative 0.0127 0.0346 0.0715
Plasmodium vivax histone deacetylase 2, putative 0.0102 0.0269 0.0918
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.016 0.0176
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0012 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0065 0.0065
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0015 0.0302
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0088 0.025
Brugia malayi Calmodulin-like protein 0.0127 0.0346 0.0393
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0083
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0065 0.0145
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0069 0.0126
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.2803
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0201 0.057 0.1193
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.0025 0.0018
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0243 0.0273
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0086 0.0088
Plasmodium falciparum serine repeat antigen 1 0.0239 0.0687 0.2395
Toxoplasma gondii microneme protein MIC17C 0.003 0.0049 0.0083
Onchocerca volvulus 0.0094 0.0244 0.0519
Echinococcus granulosus calpain 7 C02 family 0.0802 0.2408 0.2803
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0169 0.051
Echinococcus granulosus GPCR family 2 0.0034 0.0061 0.006
Onchocerca volvulus 0.0167 0.0466 0.099
Brugia malayi PXA domain containing protein 0.0042 0.0086 0.0088
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0338 0.0989 0.1145
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0086 0.0076
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Giardia lamblia Cathepsin B precursor 0.1036 0.3124 1
Schistosoma mansoni ap endonuclease 0.0019 0.0015 0.0006
Echinococcus granulosus cathepsin l cysteine peptidase 0.0944 0.2841 0.3309
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0239 0.0687 0.2175
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0029 0.0106
Schistosoma mansoni hypothetical protein 0.0127 0.0346 0.0393
Brugia malayi prolyl oligopeptidase family protein 0.0692 0.2073 0.2411
Echinococcus multilocularis histone deacetylase 6 0.0102 0.0269 0.0259
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0023 0.0015
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0075 0.0209
Leishmania major cathepsin L-like protease 0.0944 0.2841 0.6028
Giardia lamblia Cathepsin B precursor 0.0239 0.0687 0.2175
Trypanosoma cruzi kinesin, putative 0.0567 0.1688 0.1962
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Echinococcus multilocularis cathepsin L cysteine protease 0.0944 0.2841 0.2834
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0069 0.0209
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Loa Loa (eye worm) hypothetical protein 0.0109 0.0288 0.0326
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0023 0.0015
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0089 0.0253
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.003 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0086 0.0076
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0127 0.0346 0.0393
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.0465 0.0532
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0086 0.0243
Brugia malayi cathepsin L-like precursor 0.0658 0.1968 0.2288
Loa Loa (eye worm) hypothetical protein 0.0042 0.0084 0.0088
Echinococcus multilocularis cysteine protease 0.0944 0.2841 0.2834
Trypanosoma brucei Calpain-like protein CALP1.3 0.0235 0.0676 0.1418
Echinococcus multilocularis neurocalcin 0.0127 0.0346 0.0336
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0023 0.0015
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0093 0.0241 0.0269
Trypanosoma brucei histone deacetylase 1 0.0091 0.0235 0.0479
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0084 0.0087
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0012 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Loa Loa (eye worm) hypothetical protein 0.0286 0.0829 0.0959
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.029 0.0281
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.013 0.0355 0.0403
Brugia malayi Cathepsin L-like cysteine proteinase 0.0658 0.1968 0.2288
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0109 0.0116
Echinococcus multilocularis EF hand domain containing family member A2 0.013 0.0353 0.0343
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Echinococcus granulosus inhibitor of apoptosis protein 0.0155 0.0429 0.049
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0077
Schistosoma mansoni calmodulin 0.0127 0.0346 0.0393
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0824 0.2614
Trypanosoma cruzi cruzipain precursor, putative 0.1047 0.3159 0.368
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0101 0.0292
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.003 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Plasmodium falciparum plasmepsin X 0.011 0.0294 0.1005
Schistosoma mansoni tar DNA-binding protein 0.0067 0.016 0.0175
Loa Loa (eye worm) hypothetical protein 0.0294 0.0855 0.0988
Onchocerca volvulus Chorion peroxidase homolog 0.0065 0.0155 0.033
Plasmodium falciparum serine repeat antigen 9 0.0239 0.0687 0.2395
Trypanosoma brucei histone deacetylase 2 0.0044 0.009 0.0172
Brugia malayi Eukaryotic aspartyl protease family protein 0.003 0.0048 0.0045
Echinococcus multilocularis inhibitor of apoptosis protein 0.0155 0.0429 0.042
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2816 0.8566 1
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.0025 0.0019
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0086 0.0088
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0155 0.0429 0.049
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0155 0.017
Schistosoma mansoni hypothetical protein 0.0034 0.0061 0.006
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.029 0.0281
Echinococcus multilocularis neuronal calcium sensor 0.0127 0.0346 0.0336
Echinococcus multilocularis tumor protein p63 0.0703 0.2104 0.2097
Mycobacterium leprae proteasome (beta subunit) PrcB 0.009 0.023 0.1149
Schistosoma mansoni inositol monophosphatase 0.0036 0.0066 0.0065
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0243 0.0233
Loa Loa (eye worm) hypothetical protein 0.0185 0.0523 0.06
Toxoplasma gondii histone deacetylase HDAC3 0.0091 0.0235 0.0479
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0643 0.1923 0.4691
Trypanosoma brucei Calpain-like protein 2 0.0235 0.0676 0.1418
Loa Loa (eye worm) PAS-3 protein 0.0018 0.001 0.0001
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0049 0.0083
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.0824 0.2614
Mycobacterium ulcerans transglutaminase family protein 0.0247 0.0712 0.3671
Echinococcus multilocularis muscleblind protein 0.0294 0.0855 0.0846
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0189 0.021
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0239 0.0687 0.2395
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0069 0.019
Brugia malayi programmed cell death protein 6 0.0127 0.0346 0.0393
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0286 0.0829 0.0958
Loa Loa (eye worm) hypothetical protein 0.0094 0.0244 0.0275
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0026 0.0049
Trypanosoma cruzi calmodulin, putative 0.0127 0.0346 0.0393
Entamoeba histolytica calpain family cysteine protease, putative 0.0235 0.0676 0.2353
Leishmania major cathepsin L-like protease 0.0944 0.2841 0.6028
Leishmania major importin beta-1 subunit, putative 0.0025 0.0031 0.0045
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.5107
Schistosoma mansoni mitochondrial solute carrier 0.0127 0.0346 0.0393
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0066 0.0065
Echinococcus granulosus histone deacetylase 7 0.0102 0.0269 0.0303
Onchocerca volvulus 0.0094 0.0244 0.0519
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0023 0.0013
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0018 0.001 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0024 0.0031
Toxoplasma gondii hypothetical protein 0.0235 0.0676 0.1418
Schistosoma mansoni histone deacetylase 4 5 0.0102 0.0269 0.0303
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0205 0.0195
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Loa Loa (eye worm) fibroinase 0.0944 0.2841 0.331
Plasmodium vivax metacaspase 1, putative 0.0018 0.0012 0.0011
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0235 0.0676 0.1418
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0047 0.0101 0.0479
Mycobacterium ulcerans hypothetical protein 0.0024 0.0029 0.0106
Schistosoma mansoni histone deacetylase 4 5 0.0102 0.0269 0.0303
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0086 0.0088
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.2803
Echinococcus multilocularis caspase 8 0.0018 0.0012 0.0002
Loa Loa (eye worm) proteasome subunit beta type 1 0.007 0.0169 0.0187
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.5107
Brugia malayi steroid hormone receptor 0.0022 0.0023 0.0015
Onchocerca volvulus Cathepsin L homolog 0.0944 0.2841 0.6037
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.029 0.0991
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.003 0.0059
Brugia malayi Cytochrome P450 family protein 0.0089 0.0229 0.0256
Entamoeba histolytica Ran family GTPase 0.0022 0.0024 0.0051
Entamoeba histolytica cysteine protease, putative 0.0239 0.0687 0.2392
Echinococcus granulosus Glycosyl transferase family 35 0.0109 0.029 0.0328
Mycobacterium leprae Probable lipase LipE 0.0036 0.0065 0.029
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0018 0.001 0.0003
Brugia malayi Peptidase family M13 containing protein 0.0093 0.0241 0.0269
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.0448 0.0513
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0018 0.001 0.0003
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0155 0.0171
Loa Loa (eye worm) hypothetical protein 0.0094 0.0244 0.0275
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0109 0.0252
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0086 0.0089
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Plasmodium falciparum serine repeat antigen 3 0.0239 0.0687 0.2395
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0288 0.0325
Mycobacterium ulcerans proteasome PrcA 0.0018 0.001 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0239 0.0687 0.0792
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0088 0.0166
Schistosoma mansoni reticulocalbin 0.0127 0.0346 0.0393
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0045
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0023 0.0015
Echinococcus granulosus calpain A 0.2269 0.6894 0.8046
Trypanosoma brucei histone deacetylase, putative 0.0102 0.0269 0.0552
Brugia malayi Pre-SET motif family protein 0.0651 0.1945 0.2262
Onchocerca volvulus 0.0239 0.0687 0.146
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0944 0.2841 0.9092
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0024 0.0017
Plasmodium vivax plasmepsin IV, putative 0.003 0.0048 0.0138
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0015 0.0005
Schistosoma mansoni inositol monophosphatase 0.0036 0.0066 0.0065
Leishmania major metacaspase, putative 0.0018 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0094 0.0244 0.0275
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0026 0.0089
Entamoeba histolytica cysteine protease, putative 0.0239 0.0687 0.2392
Leishmania major histone deacetylase, putative 0.0091 0.0235 0.0479
Trypanosoma cruzi caltractin, putative 0.0127 0.0346 0.0393
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0355 0.0403
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.003 0.011
Plasmodium falciparum metacaspase 1 0.0018 0.0012 0.0011
Echinococcus granulosus caspase 2 0.0131 0.0355 0.0404
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0086 0.0076
Schistosoma mansoni inhibitor of apoptosis protein 0.0155 0.0429 0.049
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.0448 0.0439
Schistosoma mansoni tar DNA-binding protein 0.0067 0.016 0.0175
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0084 0.0262
Trypanosoma cruzi hypothetical protein, conserved 0.0201 0.057 0.0655
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0802 0.2408 0.2803
Onchocerca volvulus 0.0094 0.0244 0.0519
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0023 0.0015
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0235 0.0722
Trypanosoma brucei hypothetical protein, conserved 0.0127 0.0346 0.0715
Echinococcus granulosus calbindin 32 0.013 0.0353 0.04
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0944 0.2841 0.2834
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0201 0.057 0.1799
Loa Loa (eye worm) hypothetical protein 0.0093 0.0241 0.0271
Leishmania major cathepsin L-like protease 0.1047 0.3159 0.6704
Echinococcus granulosus prolyl endopeptidase 0.1554 0.4706 0.5489
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0029 0.0023
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0023 0.0015
Schistosoma mansoni cpg binding protein 0.003 0.0047 0.0043
Echinococcus granulosus EF hand domain containing family member A2 0.013 0.0353 0.04
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0003
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0465 0.0455
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Onchocerca volvulus 0.0944 0.2841 0.6037
Leishmania major programmed cell death 6 protein-like protein 0.0127 0.0346 0.0715
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.003 0.011
Echinococcus multilocularis importin subunit beta 1 0.003 0.0049 0.0039
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0239 0.0687 0.0792
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0127 0.0346 0.119
Onchocerca volvulus 0.0944 0.2841 0.6037
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0155 0.0171
Echinococcus granulosus histone acetyltransferase KAT2B 0.0157 0.0435 0.0496
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0024 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0023 0.0016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0027 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0089 0.0282
Plasmodium falciparum plasmepsin V 0.003 0.0048 0.0138
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Loa Loa (eye worm) hypothetical protein 0.0239 0.0687 0.0793
Trypanosoma brucei centrin, putative 0.0127 0.0346 0.0715
Loa Loa (eye worm) hypothetical protein 0.0658 0.1968 0.2289
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0802 0.2408 0.5107
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0066 0.0197
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0089 0.0279
Echinococcus multilocularis cathepsin b 0.2816 0.8566 0.8565
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0239 0.0687 0.2392
Brugia malayi Histone deacetylase family protein 0.0102 0.0269 0.0303
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0021
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1554 0.4706 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Brugia malayi Histone deacetylase family protein 0.0102 0.0269 0.0303
Schistosoma mansoni peroxidasin 0.0065 0.0155 0.017
Echinococcus multilocularis Glycosyl transferase, family 35 0.0109 0.029 0.0281
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0075 0.0076
Brugia malayi Cathepsin L-like precursor 0.0944 0.2841 0.3309
Trypanosoma brucei calpain, putative 0.0235 0.0676 0.1418
Schistosoma mansoni cathepsin C 0.0239 0.0687 0.0792
Loa Loa (eye worm) hypothetical protein 0.0069 0.0166 0.0184
Schistosoma mansoni coup transcription factor 0.0022 0.0023 0.0015
Giardia lamblia Glycogen phosphorylase 0.0109 0.029 0.0901
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Plasmodium falciparum histone deacetylase 1 0.0091 0.0235 0.0797
Echinococcus granulosus glycoprotein Antigen 5 0.0094 0.0244 0.0274
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0281 0.0817 0.0943
Loa Loa (eye worm) hypothetical protein 0.1554 0.4706 0.5489
Plasmodium vivax vivapain-2 0.0944 0.2841 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0239 0.0687 0.2175
Onchocerca volvulus Histone deacetylase 10 homolog 0.0044 0.009 0.0192
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Plasmodium falciparum plasmepsin IX 0.011 0.0294 0.1005
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0075 0.0209
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0086 0.0088
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0155 0.0429 0.049
Echinococcus granulosus muscleblind protein 0.0294 0.0855 0.0987
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0355 0.1805
Toxoplasma gondii EFHC1, putative 0.0127 0.0346 0.0715
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.013 0.0355 0.0345
Schistosoma mansoni ran 0.0022 0.0024 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0346 0.1079
Loa Loa (eye worm) hypothetical protein 0.0094 0.0244 0.0275
Plasmodium vivax histone deacetylase 1, putative 0.0091 0.0235 0.0797
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.003 0.0059
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0061 0.006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0023 0.0015
Echinococcus multilocularis hypothetical protein 0.0802 0.2408 0.2401
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0271 0.0305
Onchocerca volvulus 0.0944 0.2841 0.6037
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0024 0.0054
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0065 0.029
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0018 0.001 0.0003
Echinococcus granulosus cathepsin l1 0.0658 0.1968 0.2288
Trichomonas vaginalis calcium binding protein, putative 0.0127 0.0346 0.1079
Brugia malayi Papain family cysteine protease containing protein 0.0525 0.156 0.1812
Brugia malayi Probable ClpP-like protease 0.0076 0.0189 0.021
Plasmodium vivax centrin-1, putative 0.0127 0.0346 0.119
Echinococcus granulosus histone deacetylase 0.0102 0.0269 0.0303
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0155 0.0429 0.049
Trypanosoma cruzi histone deacetylase, putative 0.0102 0.0269 0.0303
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0026 0.0604
Brugia malayi prolyl oligopeptidase family protein 0.0201 0.057 0.0655
Mycobacterium ulcerans hypothetical protein 0.0247 0.0712 0.3671
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0061 0.0061
Schistosoma mansoni glycogen phosphorylase 0.0109 0.029 0.0328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0658 0.1968 0.6288
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.0676 0.2139
Entamoeba histolytica hypothetical protein 0.0042 0.0086 0.0267
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0779 0.2339 0.2722
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0235 0.0722
Entamoeba histolytica cysteine protease, putative 0.0525 0.156 0.5477
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0015 0.0022
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0024
Trichomonas vaginalis set domain proteins, putative 0.074 0.222 0.7096
Toxoplasma gondii microneme protein MIC4 0.003 0.0049 0.0083
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0048 0.0138
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.003 0.011
Echinococcus granulosus survival motor neuron protein 1 0.0489 0.1451 0.1684
Brugia malayi EF hand family protein 0.013 0.0353 0.04
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.023 0.0257
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0235 0.0676 0.0778
Entamoeba histolytica grainin 2 0.0131 0.0357 0.1225
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0044 0.0089 0.0419
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0084 0.0087
Schistosoma mansoni alpha-glucosidase 0.0143 0.0394 0.0449
Echinococcus granulosus snurportin 1 0.0323 0.0944 0.1092
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0239 0.0687 0.2395
Trichomonas vaginalis calmodulin, putative 0.013 0.0353 0.11
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0007
Brugia malayi Trypsin family protein 0.0094 0.0244 0.0274
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0643 0.1923 0.2236
Echinococcus granulosus histone deacetylase 8 0.0044 0.009 0.0094
Loa Loa (eye worm) hypothetical protein 0.0944 0.2841 0.331
Echinococcus granulosus calcium uptake protein 1 0.013 0.0353 0.04
Onchocerca volvulus 0.0094 0.0243 0.0517
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0023 0.0015
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0003
Echinococcus granulosus calpain A 0.0802 0.2408 0.2803
Loa Loa (eye worm) acetyltransferase 0.0161 0.0448 0.0514
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Brugia malayi Cytochrome P450 family protein 0.0044 0.0089 0.0093
Leishmania major cytochrome p450-like protein 0.0044 0.0089 0.0169
Onchocerca volvulus Notchless protein homolog 0.0018 0.001 0.0021
Brugia malayi Trypsin family protein 0.0094 0.0244 0.0274
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0086 0.0088
Onchocerca volvulus 0.003 0.0049 0.0103
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.003 0.0048 0.0038
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0075 0.023
Onchocerca volvulus 0.0094 0.0244 0.0519
Plasmodium vivax serine-repeat antigen (SERA) 0.0239 0.0687 0.2395
Entamoeba histolytica hypothetical protein 0.0072 0.0177 0.0588
Loa Loa (eye worm) hypothetical protein 0.2816 0.8566 1
Brugia malayi prolyl oligopeptidase family protein 0.1554 0.4706 0.5489
Schistosoma mansoni neprilysin 0.0024 0.003 0.0024
Onchocerca volvulus 0.0103 0.0271 0.0575
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.003 0.011
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0235 0.0676 0.0778
Loa Loa (eye worm) cytochrome P450 family protein 0.0089 0.0229 0.0257
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0089 0.0094
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0189 0.0943
Trypanosoma brucei hypothetical protein 0.0235 0.0676 0.1418
Onchocerca volvulus 0.003 0.0049 0.0103
Brugia malayi gamma-secretase subunit aph-1 0.0254 0.0731 0.0843
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0029 0.0023
Loa Loa (eye worm) prolyl oligopeptidase 0.0692 0.2073 0.2411
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0088 0.0166
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0281 0.0817 0.0808
Echinococcus multilocularis cathepsin b 0.2816 0.8566 0.8565
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Plasmodium falciparum plasmepsin VI 0.003 0.0048 0.0138
Echinococcus multilocularis GPCR, family 2 0.0034 0.0061 0.0051
Onchocerca volvulus 0.0036 0.0065 0.0139
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.003 0.011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0274
Echinococcus multilocularis prolyl endopeptidase 0.1554 0.4706 0.4701
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0281 0.0817 0.0943
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Leishmania major centrin, putative,caltractin, putative 0.0127 0.0346 0.0715
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0086 0.0088
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0089
Trypanosoma brucei cytochrome P450, putative 0.0044 0.0089 0.0169
Plasmodium vivax proteasome subunit beta type-5, putative 0.009 0.023 0.078
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0086 0.0088
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0802 0.2408 0.2803
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0037 0.0262
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0023 0.0013
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.009 0.023 0.0777
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0127 0.0346 0.0394
Mycobacterium tuberculosis Long conserved protein 0.0247 0.0712 0.1726
Loa Loa (eye worm) hypothetical protein 0.0239 0.0687 0.0793
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0023 0.0049
Giardia lamblia Cysteine protease 0.0239 0.0687 0.2175
Onchocerca volvulus 0.0047 0.0099 0.0211
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0048 0.0045
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0086 0.0088
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0201 0.057 0.1979
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0088 0.0091
Brugia malayi hypothetical protein 0.0042 0.0086 0.0088
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0026 0.006
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Trichomonas vaginalis centrin, putative 0.0127 0.0346 0.1079
Schistosoma mansoni ran 0.0022 0.0024 0.0017
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.016 0.0175
Toxoplasma gondii aspartyl protease ASP3 0.011 0.0294 0.0604
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0131 0.0355 0.0405
Echinococcus granulosus tumor protein p63 0.0703 0.2104 0.2448
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0018 0.001 0.0001
Trichomonas vaginalis calcineurin B subunit, putative 0.0127 0.0346 0.1079
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0112 0.0299 0.0337
Toxoplasma gondii hypothetical protein 0.003 0.0049 0.0083
Echinococcus granulosus programmed cell death protein 0.0131 0.0357 0.0405
Echinococcus multilocularis calpain 0.0802 0.2408 0.2401
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0075 0.0076
Leishmania major kinesin, putative 0.0567 0.1688 0.3574
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0016
Plasmodium falciparum centrin-1 0.0127 0.0346 0.119
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0027 0.006
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0015 0.0023
Schistosoma mansoni histone deacetylase 0.0091 0.0235 0.0263
Entamoeba histolytica cysteine protease, putative 0.0239 0.0687 0.2392
Schistosoma mansoni ap endonuclease 0.0019 0.0015 0.0006
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0018 0.001 0.0003
Trichomonas vaginalis hypothetical protein 0.0235 0.0676 0.2139
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0027 0.0093
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0239 0.0687 0.2395
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0018 0.001 0.0003
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0015 0.0012
Brugia malayi nuclear receptor NHR-88 0.0022 0.0023 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0023 0.0015
Brugia malayi hypothetical protein 0.0137 0.0375 0.0427
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0235 0.0722
Echinococcus granulosus cathepsin L 0.0239 0.0687 0.0792
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0018 0.001 0.0003
Trypanosoma brucei Calpain-like protein 1.1 0.0235 0.0676 0.1418
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0023 0.0013
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0525 0.156 0.1812
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0088 0.0091
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0299 0.1513
Onchocerca volvulus 0.003 0.0049 0.0103
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0944 0.2841 0.2834
Echinococcus granulosus enteropeptidase 0.0094 0.0244 0.0274
Trypanosoma cruzi histone deacetylase, putative 0.0102 0.0269 0.0303
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0109 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0281 0.0817 0.0943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0944 0.2841 0.9092
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.0243 0.0273
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0235 0.0676 0.0778
Mycobacterium tuberculosis Conserved hypothetical protein 0.0247 0.0712 0.1726
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0012 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2816 0.8566 1
Giardia lamblia Cathepsin L-like protease 0.0239 0.0687 0.2175
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0027 0.0051
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0069 0.019
Schistosoma mansoni histone deacetylase hda2 0.0044 0.009 0.0094
Schistosoma mansoni calpain (C02 family) 0.0802 0.2408 0.2803
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.015 0.0298
Toxoplasma gondii aldehyde dehydrogenase 0.013 0.0355 0.0734
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0065 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0023 0.0015
Brugia malayi RNA binding protein 0.0067 0.016 0.0175
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1036 0.3124 0.6631
Loa Loa (eye worm) hypothetical protein 0.0081 0.0205 0.0229
Leishmania major phospholipase c-like protein 0.0127 0.0346 0.0715
Onchocerca volvulus 0.003 0.0049 0.0103
Brugia malayi beta-lactamase family protein 0.0036 0.0065 0.0065
Loa Loa (eye worm) proteasome subunit beta type 3 0.0018 0.001 0.0001
Trypanosoma cruzi prolyl endopeptidase 0.1554 0.4706 0.5489
Echinococcus granulosus cathepsin l1 0.0944 0.2841 0.3309
Brugia malayi cathepsin F-like cysteine proteinase 0.0239 0.0687 0.0792
Schistosoma mansoni ef hand domain family member A2 0.0127 0.0346 0.0393
Echinococcus multilocularis tissue type plasminogen activator 0.0047 0.0099 0.0089
Leishmania major hypothetical protein, conserved 0.0036 0.0065 0.0118
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0037 0.0097
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0243 0.0233
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.003 0.0024
Brugia malayi Cytochrome P450 family protein 0.0044 0.0089 0.0093
Loa Loa (eye worm) hypothetical protein 0.0155 0.0429 0.0491
Schistosoma mansoni caspase-7 (C14 family) 0.0131 0.0355 0.0404
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0023 0.0016
Brugia malayi Cathepsin L-like precursor 0.0944 0.2841 0.3309
Plasmodium vivax importin-beta 2, putative 0.003 0.0049 0.014
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0015 0.0017
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0069 0.019
Loa Loa (eye worm) hypothetical protein 0.0201 0.057 0.0656
Mycobacterium leprae Conserved hypothetical protein 0.0247 0.0712 0.3667
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0235 0.0676 0.1418
Loa Loa (eye worm) EF hand family protein 0.0127 0.0346 0.0394
Trypanosoma brucei proteasome subunit beta type-5, putative 0.009 0.023 0.0468
Loa Loa (eye worm) aspartic protease BmAsp-1 0.003 0.0048 0.0046
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0274
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0023 0.0015
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0155 0.017
Plasmodium vivax calpain, putative 0.0802 0.2408 0.8472
Loa Loa (eye worm) hypothetical protein 0.0201 0.057 0.0656
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0018 0.001 0.0003
Plasmodium falciparum serine repeat antigen 4 0.0239 0.0687 0.2395
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0066 0.0179
Echinococcus multilocularis cathepsin L cysteine protease 0.0944 0.2841 0.2834
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0189 0.6411
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0018 0.001 0.0009
Leishmania major hypothetical protein, unknown function 0.0235 0.0676 0.1418
Entamoeba histolytica cysteine protease, putative 0.0239 0.0687 0.2392
Brugia malayi Cathepsin L-like precursor 0.0286 0.0829 0.0958
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0065 0.0065
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0127 0.0346 0.0393
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1036 0.3124 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0027 0.002
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0235 0.0722
Echinococcus granulosus acylamino acid releasing enzyme 0.0201 0.057 0.0655
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.003 0.0059
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0027 0.006
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0244 0.0235
Echinococcus multilocularis histone deacetylase 1 0.0091 0.0235 0.0225
Plasmodium vivax vivapain-2 0.0944 0.2841 1
Onchocerca volvulus 0.0023 0.0027 0.0057
Plasmodium falciparum plasmepsin I 0.003 0.0048 0.0138
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0069 0.019
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0012 0.0003
Mycobacterium tuberculosis Conserved protein 0.0024 0.0029 0.0057
Echinococcus granulosus peroxidasin 0.0065 0.0155 0.017
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0239 0.0687 0.2395
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0024 0.0014
Brugia malayi Histone deacetylase 1 0.0091 0.0235 0.0263
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0007
Echinococcus granulosus tar DNA binding protein 0.0067 0.016 0.0175
Schistosoma mansoni calpain C (C02 family) 0.0802 0.2408 0.2803
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0023 0.0015
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0235 0.0676 0.0778
Brugia malayi cathepsin L-like cysteine proteinase 0.0239 0.0687 0.0792
Trichomonas vaginalis calmodulin, putative 0.0127 0.0346 0.1079
Brugia malayi proteasome subunit beta type 2 0.0043 0.0088 0.0091
Loa Loa (eye worm) beta-lactamase 0.0036 0.0065 0.0066
Onchocerca volvulus 0.0065 0.0155 0.033
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0066
Giardia lamblia Proteasome subunit beta type 1 0.007 0.0169 0.051
Trypanosoma brucei caltractin, putative 0.0131 0.0357 0.0738
Brugia malayi Cathepsin L-like precursor 0.0944 0.2841 0.3309
Loa Loa (eye worm) hypothetical protein 0.0069 0.0166 0.0184
Onchocerca volvulus Dual oxidase homolog 0.0065 0.0155 0.033
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.003 0.0059
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Echinococcus multilocularis cathepsin L 0.0239 0.0687 0.0678
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.003 0.011
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.007 0.0169 0.0159
Trichomonas vaginalis calcium binding protein, putative 0.0127 0.0346 0.1079
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0802 0.2408 0.2803
Echinococcus granulosus microtubule associated protein 2 0.149 0.4511 0.526
Brugia malayi cathepsin L precursor 0.0239 0.0687 0.0792
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0127 0.0346 0.0715
Mycobacterium ulcerans hypothetical protein 0.0024 0.0029 0.0106
Loa Loa (eye worm) cysteine protease 0.0944 0.2841 0.331
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0105
Trichomonas vaginalis centrin, putative 0.0127 0.0346 0.1079
Plasmodium falciparum plasmepsin VIII, putative 0.003 0.0048 0.0138
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0024
Leishmania major protein kinase, putative 0.0127 0.0346 0.0715
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.1418
Onchocerca volvulus 0.0094 0.0244 0.0519
Schistosoma mansoni cercarial elastase (S01 family) 0.0094 0.0244 0.0274
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0189 0.0938
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0084 0.0158
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0066
Entamoeba histolytica calcium-binding protein, putative 0.0127 0.0346 0.1187
Echinococcus granulosus histone deacetylase 3 0.0091 0.0235 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0239 0.0687 0.2175
Brugia malayi Proteasome A-type and B-type family protein 0.009 0.023 0.0257
Trichomonas vaginalis calpain, putative 0.0235 0.0676 0.2139
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0061 0.006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0084 0.0239
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0048 0.0138
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Leishmania major proteasome beta 5 subunit, putative 0.009 0.023 0.0468
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.1244 0.1235
Toxoplasma gondii cathepsin CPC1 0.0239 0.0687 0.1442
Echinococcus granulosus endothelin converting enzyme 1 0.0093 0.0241 0.0269
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0086 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.003 0.0059
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0112 0.0299 0.0289
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0023 0.0013
Echinococcus granulosus transmembrane protease serine 3 0.0094 0.0244 0.0274
Schistosoma mansoni cpg binding protein 0.0031 0.0052 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0023 0.0015
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0171
Echinococcus granulosus caspase 0.0018 0.0012 0.0003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0235 0.0676 0.0778
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0088 0.0091
Schistosoma mansoni hypothetical protein 0.0518 0.1541 0.179
Brugia malayi aspartic protease BmAsp-2, identical 0.003 0.0048 0.0045
Entamoeba histolytica hypothetical protein 0.0042 0.0086 0.0267
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0065 0.0145
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0027 0.0093
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.0824 0.2875
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1047 0.3159 0.6704
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0065 0.0295
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0201 0.057 0.1799
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0089
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0026 0.0896
Schistosoma mansoni tar DNA-binding protein 0.0067 0.016 0.0175
Brugia malayi peptidase family M13 containing protein 0.0023 0.0025 0.0018
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.023 0.0257
Onchocerca volvulus Peroxidase homolog 0.0065 0.0155 0.033
Trypanosoma cruzi cysteine peptidase, putative 0.1047 0.3159 0.368
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0025 0.0018
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0779 0.2339 0.2332
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0023 0.0015
Schistosoma mansoni Mername-AA248 (C02 family) 0.0802 0.2408 0.2803
Schistosoma mansoni reticulocalbin 0.013 0.0353 0.04
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.003 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.1047 0.3159 0.368
Leishmania major calpain protease-like protein 0.0235 0.0676 0.1418
Brugia malayi Inositol-1 0.0036 0.0066 0.0065
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0018 0.0012 0.0002
Trypanosoma cruzi histone deacetylase, putative 0.0044 0.009 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.003 0.0059
Onchocerca volvulus 0.0065 0.0155 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0239 0.0687 0.2175
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0046
Mycobacterium tuberculosis Hypothetical protein 0.0247 0.0712 0.1726
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0779 0.2339 0.2722
Leishmania major i/6 autoantigen-like protein 0.0127 0.0346 0.0715
Schistosoma mansoni cathepsin F (C01 family) 0.0944 0.2841 0.3309
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0119
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0692 0.2073 0.2411
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2267 0.6887 0.6884
Onchocerca volvulus 0.0944 0.2841 0.6037
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0088 0.0092
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0084 0.0239
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0065 0.0145
Giardia lamblia Hypothetical protein 0.013 0.0353 0.11
Loa Loa (eye worm) TK/ROR protein kinase 0.0047 0.0099 0.0105
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0069 0.019
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0075 0.0139
Trypanosoma cruzi calmodulin, putative 0.0127 0.0346 0.0393
Loa Loa (eye worm) hypothetical protein 0.0074 0.0183 0.0204
Mycobacterium ulcerans hypothetical protein 0.0094 0.0244 0.1229

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 1.995262315 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 10 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 15.84893192 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 25.11886432 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (ADMET) = 1.9953 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9. (Class of assay: confirmatory) [Related pubchem assays: 885, 884, 410 ] ChEMBL. No reference
Potency (ADMET) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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