Detailed information for compound 1366061

Basic information

Technical information
  • TDR Targets ID: 1366061
  • Name: [1-[(5-chloropyridin-2-yl)amino]-1-oxopropan- 2-yl] 2-(4-ethoxyphenoxy)acetate
  • MW: 378.807 | Formula: C18H19ClN2O5
  • H donors: 1 H acceptors: 3 LogP: 3.35 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)OCC(=O)OC(C(=O)Nc1ccc(cn1)Cl)C
  • InChi: 1S/C18H19ClN2O5/c1-3-24-14-5-7-15(8-6-14)25-11-17(22)26-12(2)18(23)21-16-9-4-13(19)10-20-16/h4-10,12H,3,11H2,1-2H3,(H,20,21,23)
  • InChiKey: ADWPFCINVKNCGK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [2-[(5-chloro-2-pyridyl)amino]-1-methyl-2-oxo-ethyl] 2-(4-ethoxyphenoxy)acetate
  • 2-(4-ethoxyphenoxy)acetic acid [2-[(5-chloro-2-pyridyl)amino]-1-methyl-2-oxoethyl] ester
  • 2-(4-ethoxyphenoxy)acetic acid [2-[(5-chloro-2-pyridyl)amino]-2-keto-1-methyl-ethyl] ester
  • [1-[(5-chloropyridin-2-yl)amino]-1-oxo-propan-2-yl] 2-(4-ethoxyphenoxy)ethanoate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens snurportin 1 No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens RAN, member RAS oncogene family No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus proteasome prosome macropain 0.0174 0.0525 0.0521
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0034 0.0057 0.0054
Toxoplasma gondii ABC1 family protein 0.0036 0.0064 0.0106
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0034 0.0057 0.0054
Loa Loa (eye worm) fibroinase 0.1156 0.3805 0.3803
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Echinococcus multilocularis calpain 7 (C02 family) 0.0875 0.2868 0.2865
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0636 0.2069 0.3613
Loa Loa (eye worm) hypothetical protein 0.0282 0.0886 0.0882
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0086 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0034 0.0057 0.0054
Brugia malayi Trypsin family protein 0.0141 0.0413 0.041
Plasmodium falciparum serine repeat antigen 9 0.0282 0.0886 0.232
Trypanosoma cruzi cruzipain precursor, putative 0.1261 0.4156 0.4154
Entamoeba histolytica cysteine proteinase, putative 0.0636 0.2069 0.5419
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.025 0.0246
Plasmodium falciparum histone deacetylase 1 0.009 0.0245 0.0634
Echinococcus multilocularis histone deacetylase 3 0.009 0.0245 0.0241
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0188 0.0572 0.0568
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.0282 0.0278
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0086 0.0082
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0034 0.0057 0.0094
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0043 0.0086 0.0082
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.003 0.0045
Leishmania major hypothetical protein, conserved 0.0036 0.0064 0.0106
Brugia malayi cathepsin Z-like cysteine proteinase 0.0282 0.0886 0.0882
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0705 0.23 0.4513
Leishmania major cathepsin L-like protease 0.1156 0.3805 0.6649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Echinococcus multilocularis histone deacetylase 6 0.0101 0.0282 0.0278
Brugia malayi calcium-binding protein 0.014 0.041 0.0406
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0034 0.0057 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Mycobacterium tuberculosis Hypothetical protein 0.0284 0.0891 0.1677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Leishmania major proteasome beta 5 subunit, putative 0.0174 0.0525 0.0911
Entamoeba histolytica cysteine proteinase 1, putative 0.0636 0.2069 0.5419
Schistosoma mansoni ef hand domain family member A2 0.014 0.041 0.0406
Brugia malayi Importin beta-1 subunit 0.0035 0.006 0.0056
Brugia malayi nuclear hormone receptor 0.0022 0.0018 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Trypanosoma cruzi centrin-3 0.0143 0.0422 0.0418
Trichomonas vaginalis calmodulin, putative 0.014 0.041 0.1068
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0034 0.0057 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0031 0.0047 0.0075
Loa Loa (eye worm) trypsin family protein 0.0141 0.0413 0.041
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.041
Brugia malayi proteasome subunit alpha type 4 0.0034 0.0057 0.0054
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.1185 0.1182
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Echinococcus multilocularis proteasome subunit alpha type 6 0.0034 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0071 0.0181 0.0177
Trypanosoma cruzi I/6 autoantigen, putative 0.014 0.041 0.0406
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0875 0.2868 0.501
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0018 0.0014
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0103 0.0232
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Echinococcus multilocularis cathepsin L 0.0282 0.0886 0.0882
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0018 0.0031
Leishmania major centrin, putative 0.014 0.041 0.071
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0034 0.0057 0.0141
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0257 0.0803 0.1398
Entamoeba histolytica cysteine protease, putative 0.0282 0.0886 0.2296
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0636 0.2069 0.2066
Echinococcus granulosus cathepsin L 0.0282 0.0886 0.0882
Echinococcus multilocularis transmembrane protease serine 3 0.0141 0.0413 0.041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Leishmania major calpain protease-like protein 0.0257 0.0803 0.1398
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0282 0.0886 0.232
Trypanosoma cruzi histone deacetylase 1, putative 0.009 0.0245 0.0241
Plasmodium vivax unspecified product 0.0354 0.1127 0.2954
Schistosoma mansoni inhibitor of apoptosis protein 0.0188 0.0572 0.0568
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0042 0.0082 0.0078
Schistosoma mansoni neprilysin-2 (M13 family) 0.0049 0.0106 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0082
Schistosoma mansoni gamma-secretase subunit aph-1 0.0257 0.0802 0.0798
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0034 0.0057 0.0054
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0057 0.0094
Trypanosoma cruzi cysteine peptidase, putative 0.1156 0.3805 0.3803
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0264 0.026
Trypanosoma cruzi 20S proteasome subunit 0.0084 0.0223 0.0219
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0034 0.0057 0.0141
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0034 0.0057 0.0141
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0072 0.0068
Echinococcus multilocularis regulator of G protein signaling 0.0043 0.0086 0.0082
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.0245 0.0634
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0016 0.0031
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0034 0.0057 0.0141
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0018 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0282 0.0886 0.232
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Schistosoma mansoni calmodulin 0.014 0.041 0.0406
Plasmodium falciparum flap endonuclease 1 0.0026 0.003 0.0067
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0282 0.0886 0.232
Echinococcus granulosus tissue type plasminogen activator 0.0048 0.0103 0.0099
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0504 0.05
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0389 0.0674
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0034 0.0057 0.0054
Echinococcus granulosus cpg binding protein 0.0032 0.0051 0.0048
Brugia malayi prolyl oligopeptidase family protein 0.0303 0.0957 0.0953
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0029 0.0025
Entamoeba histolytica hypothetical protein 0.0043 0.0086 0.0187
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0034 0.0057 0.0054
Echinococcus granulosus Glycosyl transferase family 35 0.0111 0.0314 0.031
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0875 0.2868 0.2865
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0086 0.0082
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0282 0.0886 0.0882
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0282 0.0886 0.232
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0245 0.0634
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0018 0.0014
Onchocerca volvulus 0.0169 0.0507 0.0887
Trichomonas vaginalis calmodulin, putative 0.014 0.041 0.1068
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2474 0.8209 0.8208
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0022 0.0016 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Giardia lamblia Cathepsin B precursor 0.1126 0.3705 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0018 0.0014
Brugia malayi cathepsin Z-like cysteine proteinase 0.0282 0.0886 0.0882
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0404 0.1292 0.1288
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0086 0.0082
Brugia malayi beta-lactamase 0.0036 0.0064 0.006
Echinococcus multilocularis centrin 2 0.014 0.041 0.0406
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0034 0.0057 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0086 0.0217
Onchocerca volvulus 0.0282 0.0886 0.1548
Echinococcus multilocularis calbindin 32 0.0142 0.0418 0.0414
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0047 0.0043
Schistosoma mansoni ap endonuclease 0.0038 0.0072 0.0068
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Echinococcus granulosus cathepsin l1 0.1156 0.3805 0.3803
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0135 0.0395 0.0684
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Loa Loa (eye worm) calpain 5 0.0618 0.2008 0.2005
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.003 0.0067
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0057 0.0094
Plasmodium vivax histone deacetylase, putative 0.0101 0.0282 0.0732
Onchocerca volvulus 0.0031 0.0046 0.008
Mycobacterium ulcerans putative transglutaminase-like protein 0.0284 0.0891 0.3715
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0023
Toxoplasma gondii histone deacetylase HDAC2 0.009 0.0245 0.0422
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0018 0.0014
Brugia malayi Cathepsin L-like precursor 0.0354 0.1127 0.1123
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0282 0.0886 0.2359
Echinococcus granulosus Regulator of G protein signaling 20 0.0043 0.0086 0.0082
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.0803 0.08
Trypanosoma brucei calpain-like protein, putative 0.0875 0.2868 0.501
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0048 0.0103 0.0093
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0034 0.0057 0.0054
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0282 0.0886 0.232
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0034 0.0057 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0018 0.0014
Echinococcus granulosus proteasome subunit beta t family 0.0034 0.0057 0.0054
Onchocerca volvulus 0.1156 0.3805 0.6651
Trypanosoma brucei I/6 autoantigen 0.014 0.041 0.071
Plasmodium vivax proteasome subunit beta type-6, putative 0.0034 0.0057 0.0141
Brugia malayi hypothetical protein 0.0043 0.0086 0.0082
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1729 0.5721 0.5719
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0128 0.0124
Brugia malayi proteasome subunit alpha type 3 0.0034 0.0057 0.0054
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0084 0.0223 0.0383
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0141 0.0413 0.041
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.0106 0.0102
Leishmania major proteasome beta-1 subunit, putative 0.0034 0.0057 0.0094
Trypanosoma cruzi Aph-1 protein, putative 0.01 0.0278 0.0274
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Trypanosoma cruzi prolyl endopeptidase 0.1729 0.5721 0.5719
Echinococcus multilocularis programmed cell death protein 0.0143 0.0422 0.0418
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Leishmania major calmodulin, putative 0.014 0.041 0.071
Mycobacterium ulcerans hypothetical protein 0.0036 0.0064 0.003
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0047 0.0075
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0064 0.0159
Schistosoma mansoni ran 0.0026 0.0029 0.0025
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0086 0.0082
Brugia malayi proteasome subunit alpha type 2 0.0034 0.0057 0.0054
Onchocerca volvulus 0.0188 0.0572 0.0999
Echinococcus granulosus calpain A 0.2476 0.8217 0.8216
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0018 0.0014
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0257 0.0803 0.08
Trypanosoma cruzi histone deacetylase, putative 0.0044 0.0089 0.0085
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0022 0.0016 0.0031
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0038 0.0034
Trypanosoma brucei calmodulin, putative 0.014 0.041 0.071
Loa Loa (eye worm) hypothetical protein 0.0802 0.2622 0.2619
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0022 0.0018
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0034 0.0057 0.0054
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0181 0.0177
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0034 0.0057 0.0141
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.003 0.0045
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.0106 0.0102
Echinococcus granulosus proteasome subunit beta type 7 0.0034 0.0057 0.0054
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0034 0.0057 0.011
Brugia malayi Cathepsin L-like precursor 0.1156 0.3805 0.3803
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Trichomonas vaginalis set domain proteins, putative 0.0756 0.247 0.6489
Trypanosoma brucei Aph-1 protein, putative 0.01 0.0278 0.0479
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0389 0.0385
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0389 0.0385
Giardia lamblia Cathepsin L precursor 0.0282 0.0886 0.2359
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.026 0.0256
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Loa Loa (eye worm) hypothetical protein 0.0282 0.0886 0.0882
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0282 0.0886 0.2296
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0072 0.5
Toxoplasma gondii proteasome subunit alpha1, putative 0.0034 0.0057 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1156 0.3805 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0387 0.1237 0.1234
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Schistosoma mansoni hypothetical protein 0.0141 0.0413 0.041
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.055 0.1782 0.1779
Echinococcus multilocularis calcium uptake protein 1 0.0142 0.0418 0.0414
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0086 0.0082
Giardia lamblia Cathepsin L precursor 0.0282 0.0886 0.2359
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0086 0.0082
Loa Loa (eye worm) histone deacetylase 1 0.009 0.0245 0.0241
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0303 0.0957 0.1667
Echinococcus multilocularis cathepsin L cysteine protease 0.1156 0.3805 0.3803
Onchocerca volvulus 0.0141 0.0413 0.0723
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0282 0.0886 0.232
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.006 0.0097
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.0816 0.0812
Loa Loa (eye worm) hypothetical protein 0.0055 0.0128 0.0124
Onchocerca volvulus 0.0141 0.0413 0.0723
Loa Loa (eye worm) hypothetical protein 0.0035 0.006 0.0056
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.0803 0.08
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0022 0.0018
Brugia malayi Serine protease Z688.6 precursor 0.0022 0.0016 0.0012
Brugia malayi EF hand family protein 0.014 0.041 0.0406
Trichomonas vaginalis calmodulin, putative 0.014 0.041 0.1068
Brugia malayi aspartic protease BmAsp-2, identical 0.0042 0.0082 0.0078
Giardia lamblia 20S proteasome alpha subunit 1 0.0034 0.0057 0.0113
Brugia malayi Flap endonuclease-1 0.0026 0.003 0.0026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Brugia malayi calpain 5 0.0257 0.0803 0.08
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0034 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0188 0.0572 0.0568
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0023
Brugia malayi Cytochrome P450 family protein 0.0035 0.0061 0.0058
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0705 0.23 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0064 0.0159
Brugia malayi Peptidase family M13 containing protein 0.0096 0.0265 0.0261
Loa Loa (eye worm) prolyl oligopeptidase 0.0208 0.0637 0.0634
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0282 0.0886 0.0882
Brugia malayi Papain family cysteine protease containing protein 0.0636 0.2069 0.2066
Leishmania major cathepsin L-like protease 0.1156 0.3805 0.6649
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.055 0.1782 0.1779
Loa Loa (eye worm) hypothetical protein 0.0802 0.2622 0.2619
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0084 0.0223 0.0577
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0082
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0042 0.0082 0.0206
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.0086 0.0082
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0064 0.0014
Loa Loa (eye worm) RGS-3 protein 0.0043 0.0086 0.0082
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0034 0.0057 0.0054
Brugia malayi hypothetical protein 0.0141 0.0413 0.041
Schistosoma mansoni rab 0.014 0.041 0.0406
Loa Loa (eye worm) hypothetical protein 0.301 1 1
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0084 0.0223 0.0383
Onchocerca volvulus 0.0042 0.0082 0.0144
Entamoeba histolytica cysteine proteinase, putative 0.0636 0.2069 0.5419
Plasmodium vivax proteasome subunit beta type-4, putative 0.0034 0.0057 0.0141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0636 0.2069 0.3613
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0034 0.0057 0.011
Loa Loa (eye worm) hypothetical protein 0.1729 0.5721 0.5719
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0086 0.0082
Brugia malayi Papain family cysteine protease containing protein 0.0636 0.2069 0.2066
Schistosoma mansoni hypothetical protein 0.0164 0.049 0.0486
Plasmodium falciparum histone deacetylase 2 0.0101 0.0282 0.0732
Schistosoma mansoni calpain-2 (C02 family) 0.0257 0.0803 0.08
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0057 0.0054
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0034 0.0057 0.0141
Echinococcus granulosus glycogen phosphorylase 0.0111 0.0314 0.031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0018 0.0014
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0084 0.0223 0.0219
Loa Loa (eye worm) TK/ROR protein kinase 0.0048 0.0103 0.0099
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.2865
Entamoeba histolytica cysteine protease, putative 0.0282 0.0886 0.2296
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0034 0.0057 0.0054
Brugia malayi histone deacetylase 1 (HD1) 0.009 0.0245 0.0241
Brugia malayi 20S proteasome alpha5 subunit 0.0034 0.0057 0.0054
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.026 0.0256
Loa Loa (eye worm) hypothetical protein 0.0058 0.0137 0.0133
Toxoplasma gondii microneme protein, putative 0.0031 0.0047 0.0075
Brugia malayi steroid hormone receptor 0.0022 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0018 0.0014
Plasmodium falciparum cysteine proteinase falcipain 3 0.1156 0.3805 1
Giardia lamblia Cysteine protease 0.0282 0.0886 0.2359
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0018 0.0014
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0034 0.0057 0.011
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0043 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.014 0.041 0.0406
Echinococcus granulosus histone deacetylase 6 0.0101 0.0282 0.0278
Loa Loa (eye worm) PAS-3 protein 0.0034 0.0057 0.0054
Trypanosoma brucei Calpain-like protein CALP1.3 0.0257 0.0803 0.1398
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0034 0.0057 0.0054
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.0717 0.1326
Trypanosoma cruzi Aph-1 protein, putative 0.01 0.0278 0.0274
Onchocerca volvulus Dual oxidase homolog 0.0168 0.0504 0.0881
Trypanosoma cruzi centrin, putative 0.0143 0.0422 0.0418
Echinococcus granulosus flap endonuclease 1 0.0026 0.003 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0064 0.006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0121 0.0117
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.0022 0.0018
Leishmania major proteasome alpha 3 subunit, putative 0.0034 0.0057 0.0094
Toxoplasma gondii histone deacetylase HDAC4 0.0044 0.0089 0.0148
Schistosoma mansoni histone deacetylase 4 5 0.0101 0.0282 0.0278
Onchocerca volvulus 0.0022 0.0016 0.0027
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0072 0.0028
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0034 0.0057 0.0094
Brugia malayi nuclear receptor NHR-88 0.0022 0.0018 0.0014
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0034 0.0057 0.011
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0034 0.0057 0.0094
Schistosoma mansoni hypothetical protein 0.0141 0.0413 0.041
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0086 0.0082
Loa Loa (eye worm) beta-lactamase 0.0036 0.0064 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0047 0.0075
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0034 0.0057 0.011
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2334 0.7742 0.7741
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0504 0.05
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0034 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0282 0.0886 0.0882
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0042 0.0082 0.0078
Schistosoma mansoni memapsin-2 (A01 family) 0.0494 0.1593 0.1589
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0257 0.0803 0.2103
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Giardia lamblia Cathepsin L precursor 0.0282 0.0886 0.2359
Giardia lamblia Cysteine protease 0.0282 0.0886 0.2359
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0057 0.0054
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0208 0.0637 0.1667
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0064 0.006
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0043
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0257 0.0803 0.2103
Echinococcus granulosus cathepsin b 0.301 1 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0018 0.0014
Echinococcus multilocularis Regulator of G protein signaling 20 0.0043 0.0086 0.0082
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Brugia malayi PXA domain containing protein 0.0043 0.0086 0.0082
Leishmania major histone deacetylase, putative 0.0101 0.0282 0.0487
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.055 0.1782 0.3116
Leishmania major kinesin, putative 0.0618 0.2008 0.3505
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0282 0.0886 0.232
Trypanosoma cruzi major cysteine proteinase, putative 0.0282 0.0886 0.0882
Trypanosoma brucei prolyl oligopeptidase, putative 0.0705 0.23 0.4017
Leishmania major hypothetical protein, conserved 0.0257 0.0803 0.1398
Brugia malayi prolyl oligopeptidase family protein 0.0208 0.0637 0.0634
Echinococcus granulosus dnaJ subfamily B 0.0437 0.1402 0.1399
Entamoeba histolytica protein kinase, putative 0.0618 0.2008 0.5257
Toxoplasma gondii preprocathepsin c precursor, putative 0.0282 0.0886 0.1542
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0705 0.23 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0181 0.0177
Loa Loa (eye worm) hypothetical protein 0.0096 0.0263 0.0259
Trypanosoma brucei centrin, putative 0.014 0.041 0.071
Echinococcus granulosus Proteasome subunit alpha type 7 0.0034 0.0057 0.0054
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0135 0.0395 0.0391
Schistosoma mansoni hypothetical protein 0.0053 0.0121 0.0117
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0029 0.0044
Plasmodium falciparum serine repeat antigen 3 0.0282 0.0886 0.232
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0047 0.0075
Schistosoma mansoni peroxidasin 0.0168 0.0504 0.05
Toxoplasma gondii proteasome subunit alpha type, putative 0.0034 0.0057 0.0094
Loa Loa (eye worm) proteasome subunit beta type 2 0.0084 0.0223 0.0219
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0141 0.0413 0.041
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0034 0.0057 0.011
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0389 0.0385
Loa Loa (eye worm) hypothetical protein 0.0282 0.0886 0.0882
Brugia malayi calpain 5 0.0618 0.2008 0.2005
Plasmodium falciparum plasmepsin VIII, putative 0.0042 0.0082 0.0206
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.301 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0012
Onchocerca volvulus 0.0048 0.0103 0.0179
Brugia malayi Cathepsin L-like precursor 0.1156 0.3805 0.3803
Loa Loa (eye worm) hypothetical protein 0.0257 0.0803 0.08
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Echinococcus multilocularis glycoprotein Antigen 5 0.0141 0.0413 0.041
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0034 0.0057 0.0141
Trichomonas vaginalis calcineurin B subunit, putative 0.0142 0.0418 0.1089
Trypanosoma brucei calpain-like protein, putative 0.0875 0.2868 0.501
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1126 0.3705 0.6473
Giardia lamblia Glycogen phosphorylase 0.0111 0.0314 0.0809
Plasmodium falciparum plasmepsin VI 0.0042 0.0082 0.0206
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0027 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0018 0.0014
Brugia malayi Cathepsin L-like precursor 0.1156 0.3805 0.3803
Entamoeba histolytica prolyl oligopeptidase family protein 0.0208 0.0637 0.1641
Schistosoma mansoni calmodulin related calcium binding protein 0.014 0.041 0.0406
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0086 0.0082
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0282 0.0886 0.0882
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Toxoplasma gondii cathepsin CPC2 0.0282 0.0886 0.1542
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0389 0.1479
Echinococcus granulosus histone deacetylase 3 0.009 0.0245 0.0241
Plasmodium vivax proteasome subunit beta type-5, putative 0.0174 0.0525 0.137
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0282 0.0886 0.232
Trypanosoma cruzi calmodulin, putative 0.014 0.041 0.0406
Loa Loa (eye worm) proteasome subunit beta type 1 0.0135 0.0395 0.0391
Schistosoma mansoni coup transcription factor 0.0022 0.0018 0.0014
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Onchocerca volvulus 0.0168 0.0504 0.0881
Echinococcus multilocularis calmodulin 0.014 0.041 0.0406
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0072 0.0178
Schistosoma mansoni cathepsin D (A01 family) 0.0228 0.0707 0.0703
Brugia malayi hypothetical protein 0.0042 0.0082 0.0078
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0018 0.0014
Brugia malayi Pre-SET motif family protein 0.0096 0.0264 0.026
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0174 0.0525 0.0521
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.003 0.0038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.0803 0.08
Plasmodium vivax proteasome subunit beta type-2, putative 0.0084 0.0223 0.0577
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0018 0.0014
Mycobacterium tuberculosis Conserved protein 0.0284 0.0891 0.1677
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0139 0.0135
Echinococcus multilocularis tissue type plasminogen activator 0.0048 0.0103 0.0099
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0875 0.2868 0.2865
Loa Loa (eye worm) hypothetical protein 0.0096 0.0265 0.0261
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0103 0.0232
Echinococcus multilocularis EF hand domain containing family member A2 0.014 0.041 0.0406
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0086 0.0082
Brugia malayi calpain family protein 1 0.2334 0.7742 0.7741
Echinococcus multilocularis enteropeptidase 0.0141 0.0413 0.041
Toxoplasma gondii troponin c, isotype gamma, putative 0.014 0.041 0.071
Brugia malayi PXA domain containing protein 0.0043 0.0086 0.0082
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0282 0.0886 0.0882
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0034 0.0057 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0018 0.0014
Schistosoma mansoni histone deacetylase 0.009 0.0245 0.0241
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0389 0.1479
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0072 0.0148
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0034 0.0057 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1126 0.3705 0.9736
Entamoeba histolytica Ran family GTPase 0.0026 0.0029 0.0035
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0022 0.0016 0.0012
Plasmodium falciparum proteasome subunit beta type-5 0.0174 0.0525 0.137
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0048 0.0103 0.0205
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.0071 0.0181 0.0177
Trypanosoma cruzi caltractin, putative 0.014 0.041 0.0406
Echinococcus granulosus EF HAND 1 calcium binding site 0.014 0.041 0.0406
Schistosoma mansoni neuronal calcium sensor 0.014 0.041 0.0406
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0034 0.0057 0.0054
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0034 0.0057 0.0141
Onchocerca volvulus 0.0284 0.0891 0.1557
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Entamoeba histolytica cysteine proteinase, putative 0.0636 0.2069 0.5419
Toxoplasma gondii microneme protein MIC17C 0.0031 0.0047 0.0075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0082
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0086 0.0082
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0303 0.0957 0.1667
Plasmodium falciparum plasmepsin II 0.0042 0.0082 0.0206
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0034 0.0057 0.0094
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0303 0.0957 0.0953
Entamoeba histolytica cysteine proteinase 2 0.0636 0.2069 0.5419
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0057 0.0094
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0303 0.0957 0.0953
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0086 0.0082
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0389 0.1479
Trypanosoma brucei calpain-like protein, putative 0.0875 0.2868 0.501
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0072 0.0178
Plasmodium vivax vivapain-2 0.1156 0.3805 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Trichomonas vaginalis calmodulin, putative 0.0143 0.0422 0.11
Toxoplasma gondii PAN/Apple domain-containing protein 0.0031 0.0047 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0018 0.0014
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1522 0.5027 1
Loa Loa (eye worm) hypothetical protein 0.2334 0.7742 0.7741
Toxoplasma gondii microneme protein MIC17A 0.0031 0.0047 0.0075
Brugia malayi Papain family cysteine protease containing protein 0.0282 0.0886 0.0882
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0029 0.0066
Mycobacterium leprae probable zinc metalloprotease 0.0096 0.0265 0.0926
Echinococcus multilocularis calpain 0.0875 0.2868 0.2865
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0174 0.0525 0.1343
Onchocerca volvulus Peroxidase homolog 0.0168 0.0504 0.0881
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0034 0.0057 0.0054
Brugia malayi Kringle domain containing protein 0.0048 0.0103 0.0099
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0022 0.0016 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Onchocerca volvulus 0.0031 0.0047 0.0081
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0046 0.0042
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0057 0.0141
Loa Loa (eye worm) prolyl oligopeptidase 0.055 0.1782 0.1779
Brugia malayi peptidase family M13 containing protein 0.0023 0.0022 0.0018
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0142 0.0418 0.0414
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0034 0.0057 0.0094
Trichomonas vaginalis glycogen phosphorylase, putative 0.0111 0.0314 0.0816
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.014 0.041 0.0406
Onchocerca volvulus 0.014 0.041 0.0717
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0034 0.0057 0.0054
Plasmodium vivax vivapain-3 0.0636 0.2069 0.5433
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0057 0.0054
Giardia lamblia Hypothetical protein 0.0282 0.0886 0.2359
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0034 0.0057 0.0054
Echinococcus multilocularis calmodulin 0.014 0.041 0.0406
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Trypanosoma brucei antigen, putative 0.0875 0.2868 0.501
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0096 0.0265 0.0261
Trypanosoma cruzi cysteine peptidase, putative 0.0636 0.2069 0.2066
Loa Loa (eye worm) hypothetical protein 0.0354 0.1127 0.1123
Plasmodium vivax proteasome subunit beta type-3, putative 0.0034 0.0057 0.0141
Loa Loa (eye worm) hypothetical protein 0.0048 0.0103 0.0099
Echinococcus multilocularis microtubule associated protein 2 0.1526 0.504 0.5038
Entamoeba histolytica calmodulin, putative 0.014 0.041 0.1041
Plasmodium vivax hypothetical protein, conserved 0.0208 0.0637 0.1667
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0018 0.0014
Echinococcus granulosus apoptotic protease activating factor 1 0.0141 0.0414 0.041
Entamoeba histolytica cysteine protease, putative 0.0282 0.0886 0.2296
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.0245 0.0634
Echinococcus granulosus microtubule associated protein 2 0.1526 0.504 0.5038
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0086 0.0217
Echinococcus granulosus Proteasome subunit alpha beta 0.0034 0.0057 0.0054
Leishmania major calmodulin, putative 0.014 0.041 0.071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0802 0.2622 0.6886
Giardia lamblia 20S proteasome alpha subunit 5 0.0034 0.0057 0.0113
Plasmodium falciparum serine repeat antigen 4 0.0282 0.0886 0.232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0886 0.232
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0018 0.0031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0282 0.0886 0.2359
Plasmodium falciparum plasmepsin IV 0.0042 0.0082 0.0206
Onchocerca volvulus 0.1156 0.3805 0.6651
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0034 0.0057 0.011
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0354 0.035
Echinococcus granulosus histone deacetylase 6 0.0101 0.0282 0.0278
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Trypanosoma brucei oligopeptidase b 0.0705 0.23 0.4017
Echinococcus multilocularis cysteine protease 0.1156 0.3805 0.3803
Entamoeba histolytica glycogen phosphorylase, putative 0.0111 0.0314 0.0787
Echinococcus multilocularis peroxidasin 0.0168 0.0504 0.05
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.0816 0.0812
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0022 0.0016 0.0021
Plasmodium falciparum serine repeat antigen 6 0.0282 0.0886 0.232
Echinococcus multilocularis tumor protein p63 0.0378 0.1205 0.1201
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0047 0.0043
Brugia malayi proteasome subunit beta type 2 0.0084 0.0223 0.0219
Giardia lamblia Alanyl dipeptidyl peptidase 0.0208 0.0637 0.1685
Plasmodium falciparum calpain 0.0257 0.0803 0.2103
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.006
Leishmania major cathepsin L-like protease 0.1156 0.3805 0.6649
Loa Loa (eye worm) hypothetical protein 0.1716 0.5677 0.5675
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.0803 0.08
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Echinococcus multilocularis endothelin converting enzyme 1 0.0096 0.0265 0.0261
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0245 0.0634
Giardia lamblia 20S proteasome alpha subunit 3 0.0034 0.0057 0.0113
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0208 0.0637 0.1667
Echinococcus granulosus glycoprotein Antigen 5 0.0141 0.0413 0.041
Trypanosoma brucei caltractin, putative 0.0143 0.0422 0.0731
Plasmodium falciparum serine repeat antigen 8 0.0282 0.0886 0.232
Plasmodium falciparum serine repeat antigen 2 0.0282 0.0886 0.232
Echinococcus granulosus calcium uptake protein 1 0.0142 0.0418 0.0414
Giardia lamblia Cathepsin L precursor 0.0282 0.0886 0.2359
Entamoeba histolytica cysteine protease, putative 0.1156 0.3805 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Loa Loa (eye worm) hypothetical protein 0.0261 0.0816 0.0812
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0018 0.0014
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0282 0.0886 0.232
Leishmania major proteasome alpha 2 subunit, putative 0.0034 0.0057 0.0094
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0064 0.0159
Schistosoma mansoni histone deacetylase 1 2 3 0.0044 0.0089 0.0085
Schistosoma mansoni cpg binding protein 0.0032 0.0051 0.0048
Mycobacterium ulcerans lipase LipD 0.0036 0.0064 0.003
Trichomonas vaginalis ran, putative 0.0026 0.0029 0.0066
Trypanosoma brucei histone deacetylase 2 0.0044 0.0089 0.0148
Brugia malayi fibroinase precursor 0.0282 0.0886 0.0882
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0875 0.2868 0.2865
Mycobacterium tuberculosis Probable peptidase 0.0705 0.23 0.4513
Loa Loa (eye worm) hypothetical protein 0.2077 0.6882 0.6881
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0034 0.0057 0.0054
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0034 0.0057 0.0054
Brugia malayi Eukaryotic aspartyl protease family protein 0.0042 0.0082 0.0078
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0034 0.0057 0.0054
Plasmodium vivax importin-beta 2, putative 0.0035 0.006 0.0146
Onchocerca volvulus 0.0031 0.0047 0.0081
Brugia malayi carbohydrate phosphorylase 0.0111 0.0314 0.031
Entamoeba histolytica glycogen phosphorylase, putative 0.0111 0.0314 0.0787
Onchocerca volvulus Peroxidase homolog 0.0168 0.0504 0.0881
Schistosoma mansoni reticulocalbin 0.0142 0.0418 0.0414
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.014 0.041 0.1068
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.003 0.0026
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0084 0.0223 0.0577
Toxoplasma gondii peptidase, T1 family protein 0.0034 0.0057 0.0094
Brugia malayi cathepsin L-like precursor 0.0802 0.2622 0.2619
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.003 0.0067
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0705 0.23 0.2297
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2474 0.8209 0.8208
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0064 0.006
Leishmania major protein kinase, putative 0.014 0.041 0.071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Echinococcus granulosus calpain 7 C02 family 0.0875 0.2868 0.2865
Echinococcus granulosus programmed cell death protein 0.0143 0.0422 0.0418
Leishmania major calpain family cysteine protease-like protein 0.0257 0.0803 0.1398
Loa Loa (eye worm) cysteine protease 0.1156 0.3805 0.3803
Trichomonas vaginalis conserved hypothetical protein 0.014 0.041 0.1068
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0057 0.0054
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0064 0.006
Echinococcus multilocularis beta adrenergic receptor kinase 0.0043 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0086 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0018 0.0014
Schistosoma mansoni hypothetical protein 0.0257 0.0803 0.08
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0389 0.0674
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0086 0.0082
Giardia lamblia Cathepsin B precursor 0.0282 0.0886 0.2359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0886 0.232
Toxoplasma gondii histone deacetylase HDAC1 0.0101 0.0282 0.0487
Brugia malayi Histone deacetylase family protein 0.0101 0.0282 0.0278
Brugia malayi Proteasome A-type and B-type family protein 0.0034 0.0057 0.0054
Loa Loa (eye worm) calpain D 0.0257 0.0803 0.08
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Trichomonas vaginalis calcium binding protein, putative 0.0143 0.0422 0.11
Leishmania major hypothetical protein, conserved 0.014 0.041 0.071
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0034 0.0057 0.011
Giardia lamblia Cysteine protease 0.0282 0.0886 0.2359
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0282 0.0886 0.232
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0034 0.0057 0.0054
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Brugia malayi Cathepsin L-like precursor 0.1156 0.3805 0.3803
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0257 0.0803 0.1398
Entamoeba histolytica histone deacetylase, putative 0.009 0.0245 0.0605
Mycobacterium ulcerans beta-lactamase 0.0036 0.0064 0.003
Schistosoma mansoni histone deacetylase hda2 0.0108 0.0303 0.03
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0064 0.0159
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.0022 0.0018
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0174 0.0525 0.0521
Trichomonas vaginalis calmodulin, putative 0.014 0.041 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0086 0.0217
Mycobacterium ulcerans hypothetical protein 0.0284 0.0891 0.3715
Loa Loa (eye worm) hypothetical protein 0.0802 0.2622 0.2619
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0034 0.0057 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Onchocerca volvulus 0.0141 0.0413 0.0723
Schistosoma mansoni calpain-7 (C02 family) 0.0878 0.2878 0.2875
Loa Loa (eye worm) hypothetical protein 0.0141 0.0414 0.041
Echinococcus granulosus inhibitor of apoptosis protein 0.0188 0.0572 0.0568
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0103 0.0099
Trichomonas vaginalis calcium binding proteins, putative 0.014 0.041 0.1068
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0135 0.0395 0.0391
Entamoeba histolytica grainin, putative 0.0142 0.0418 0.1062
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0034 0.0057 0.0141
Echinococcus granulosus neurocalcin 0.014 0.041 0.0406
Trypanosoma cruzi histone deacetylase 1, putative 0.009 0.0245 0.0241
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0086 0.0082
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0064 0.0014
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0907 0.2973 0.297
Loa Loa (eye worm) hypothetical protein 0.0208 0.0637 0.0634
Giardia lamblia Proteasome subunit beta type 2 0.0084 0.0223 0.0562
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0257 0.0803 0.08
Brugia malayi Cathepsin L-like precursor 0.0802 0.2622 0.2619
Echinococcus granulosus neuronal calcium sensor 0.014 0.041 0.0406
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0072 0.0063
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0034 0.0057 0.0054
Echinococcus multilocularis calpain A 0.2476 0.8217 0.8216
Brugia malayi aspartic protease BmAsp-1, identical 0.0042 0.0082 0.0078
Schistosoma mansoni neuronal calcium sensor 0.014 0.041 0.0406
Loa Loa (eye worm) hypothetical protein 0.0042 0.0082 0.0078
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0141 0.0413 0.041
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0282 0.0886 0.0882
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0048 0.0103 0.0261
Mycobacterium tuberculosis Conserved hypothetical protein 0.0284 0.0891 0.1677
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0057 0.0141
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0049 0.0106 0.0102
Schistosoma mansoni centrin 0.014 0.041 0.0406
Brugia malayi regulator of G-protein signaling rgs-7 0.0043 0.0086 0.0082
Trypanosoma brucei calpain, putative 0.0257 0.0803 0.1398
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0096 0.0265 0.0418
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0038 0.0088
Trypanosoma cruzi conserved protein 0.0257 0.0803 0.08
Echinococcus multilocularis geminin 0.0164 0.049 0.0486
Echinococcus granulosus cathepsin L 0.0636 0.2069 0.2066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0064 0.0014
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0018 0.0014
Onchocerca volvulus Peroxidasin homolog 0.0168 0.0504 0.0881
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0047 0.0043
Plasmodium falciparum proteasome subunit beta type-4 0.0034 0.0057 0.0141
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.301 1 1
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0042 0.0082 0.0078
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.0022 0.0018
Plasmodium falciparum plasmepsin III 0.0042 0.0082 0.0206
Echinococcus granulosus Dipeptidyl peptidase 9 0.0303 0.0957 0.0953
Trypanosoma cruzi cysteine proteinase, putative 0.0636 0.2069 0.2066
Schistosoma mansoni glycogen phosphorylase 0.0111 0.0314 0.031
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0057 0.0094
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0188 0.0572 0.0568
Trichomonas vaginalis calpain, putative 0.0257 0.0803 0.2103
Echinococcus multilocularis cysteine protease 0.1156 0.3805 0.3803
Loa Loa (eye worm) hypothetical protein 0.1459 0.4817 0.4815
Trichomonas vaginalis hypothetical protein 0.0257 0.0803 0.2103
Trypanosoma brucei Calpain-like protein 1.1 0.0257 0.0803 0.1398
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0208 0.0637 0.1641
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0043
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0034 0.0057 0.0054
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1729 0.5721 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Echinococcus multilocularis importin subunit beta 1 0.0035 0.006 0.0056
Brugia malayi Histone deacetylase 1 0.009 0.0245 0.0241
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0389 0.0385
Echinococcus granulosus histone deacetylase 0.0101 0.0282 0.0278
Loa Loa (eye worm) hypothetical protein 0.0188 0.0572 0.0568
Brugia malayi cathepsin F-like cysteine proteinase 0.0282 0.0886 0.0882
Entamoeba histolytica calcium-binding protein, putative 0.014 0.041 0.1041
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0174 0.0525 0.094
Loa Loa (eye worm) hypothetical protein 0.0354 0.1127 0.1123
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Echinococcus granulosus Transglutaminase 0.0284 0.0891 0.0887
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0018 0.0014
Plasmodium falciparum plasmepsin X 0.0202 0.0617 0.1614
Entamoeba histolytica calpain large subunit domain III containing protein 0.0618 0.2008 0.5257
Toxoplasma gondii histone deacetylase HDAC5 0.0044 0.009 0.015
Echinococcus multilocularis calpain family protein 1, d 0.1716 0.5677 0.5675
Trichomonas vaginalis calmodulin-2, putative 0.014 0.041 0.1068
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0135 0.0395 0.1001
Trypanosoma cruzi cruzipain precursor, putative 0.0354 0.1127 0.1123
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0057 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0034 0.0057 0.0054
Echinococcus granulosus histone deacetylase 6 0.0108 0.0303 0.03
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0018 0.0014
Leishmania major hypothetical protein, conserved 0.0142 0.0418 0.0724
Echinococcus granulosus snurportin 1 0.0372 0.1185 0.1182
Toxoplasma gondii calcium-dependent protein kinase 0.0142 0.0418 0.0724
Leishmania major cathepsin L-like protease 0.1261 0.4156 0.7264
Brugia malayi EF hand family protein 0.0142 0.0418 0.0414
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0034 0.0057 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0018 0.0014
Plasmodium falciparum cysteine proteinase falcipain 1 0.0636 0.2069 0.5433
Schistosoma mansoni importin beta-1 0.0035 0.006 0.0056
Brugia malayi Trypsin family protein 0.0141 0.0413 0.041
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0303 0.0957 0.0953
Brugia malayi Protein kinase domain containing protein 0.0048 0.0103 0.0099
Schistosoma mansoni glycogen phosphorylase 0.0048 0.0103 0.01
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.0082 0.0206
Giardia lamblia Proteasome subunit beta type 3 0.0034 0.0057 0.0113
Plasmodium vivax centrin-1, putative 0.014 0.041 0.1068
Entamoeba histolytica hypothetical protein 0.0028 0.0038 0.0058
Onchocerca volvulus 0.0168 0.0504 0.0881
Onchocerca volvulus Cell death protein 3 homolog 0.0159 0.0474 0.0829
Leishmania major calcineurin B subunit, putative 0.014 0.041 0.071
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0064 0.0159
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0282 0.0886 0.0882
Trypanosoma cruzi centrin, putative 0.0143 0.0422 0.0418
Echinococcus granulosus proteasome subunit alpha type 2 0.0034 0.0057 0.0054
Plasmodium vivax plasmepsin V, putative 0.0042 0.0082 0.0206
Onchocerca volvulus 0.0141 0.0413 0.0723
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0043
Schistosoma mansoni ap endonuclease 0.0038 0.0072 0.0068
Brugia malayi Proteasome A-type and B-type family protein 0.0174 0.0525 0.0521
Echinococcus multilocularis calumenin 0.0142 0.0418 0.0414
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0064 0.006
Echinococcus granulosus calpain A 0.0875 0.2868 0.2865
Trypanosoma brucei kinesin, putative 0.0618 0.2008 0.3505
Echinococcus granulosus cathepsin l cysteine peptidase 0.1156 0.3805 0.3803
Brugia malayi hypothetical protein 0.0168 0.0504 0.05
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0174 0.0525 0.138
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0061 0.0018
Trypanosoma cruzi oligopeptidase b 0.0705 0.23 0.2297
Echinococcus multilocularis proteasome subunit beta type 6 0.0034 0.0057 0.0054
Toxoplasma gondii hypothetical protein 0.0208 0.0637 0.1108
Plasmodium falciparum plasmepsin I 0.0042 0.0082 0.0206
Plasmodium vivax serine-repeat antigen (SERA) 0.0282 0.0886 0.232
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1156 0.3805 0.3803
Giardia lamblia Hypothetical protein 0.0284 0.0891 0.2372
Trichomonas vaginalis calmodulin, putative 0.014 0.041 0.1068
Trichomonas vaginalis centrin, putative 0.014 0.041 0.1068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.026 0.0256
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0034 0.0057 0.0054
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Leishmania major hypothetical protein, conserved 0.0048 0.0103 0.0174
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0257 0.0803 0.2103
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0636 0.2069 0.2066
Trypanosoma brucei protein I/6 0.014 0.041 0.071
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0022 0.0016 0.0031
Schistosoma mansoni calmodulin 0.014 0.041 0.0406
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0208 0.0637 0.1108
Echinococcus multilocularis caspase 2 0.0159 0.0474 0.0471
Mycobacterium ulcerans hypothetical protein 0.0284 0.0891 0.3715
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0504 0.05
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0034 0.0057 0.0054
Schistosoma mansoni hypothetical protein 0.014 0.041 0.0406
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0029 0.0025
Echinococcus multilocularis histone deacetylase 8 0.0044 0.0089 0.0085
Onchocerca volvulus 0.014 0.041 0.0717
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Brugia malayi Pre-SET motif family protein 0.0665 0.2164 0.2161
Onchocerca volvulus 0.0036 0.0064 0.0112
Brugia malayi proteasome subunit alpha type 6 0.0034 0.0057 0.0054
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0034 0.0057 0.0054
Entamoeba histolytica cysteine proteinase, putative 0.1156 0.3805 1
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0245 0.0634
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0004 0.000000019489
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0264 0.0454
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0018 0.0014
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Toxoplasma gondii proteasome subunit beta type, putative 0.0174 0.0525 0.0911
Echinococcus granulosus acylamino acid releasing enzyme 0.0208 0.0637 0.0634
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0034 0.0057 0.0054
Schistosoma mansoni histone deacetylase 0.009 0.0245 0.0241
Trypanosoma brucei calpain, putative 0.0257 0.0803 0.1398
Leishmania major cathepsin L-like protease 0.1156 0.3805 0.6649
Echinococcus granulosus transmembrane protease serine 3 0.0141 0.0413 0.041
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Mycobacterium ulcerans transglutaminase family protein 0.0284 0.0891 0.3715
Trichomonas vaginalis conserved hypothetical protein 0.0282 0.0886 0.232
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0257 0.0803 0.2103
Loa Loa (eye worm) hypothetical protein 0.0064 0.0158 0.0154
Onchocerca volvulus Cathepsin F homolog 0.1156 0.3805 0.6651
Entamoeba histolytica cysteine protease, putative 0.0282 0.0886 0.2296
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0034 0.0057 0.0054
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.0086 0.0082
Brugia malayi hypothetical protein 0.0169 0.0507 0.0504
Brugia malayi calpain 7 0.0875 0.2868 0.2865
Echinococcus multilocularis Glycosyl transferase, family 35 0.0111 0.0314 0.031
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.0282 0.0278
Onchocerca volvulus 0.0031 0.0047 0.0081
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0245 0.0634
Toxoplasma gondii EFHC1, putative 0.014 0.041 0.071
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0257 0.0803 0.08
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0061 0.0058
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0282 0.0886 0.232
Brugia malayi proteasome subunit alpha type 1 0.0034 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0169 0.0507 0.0504
Toxoplasma gondii microneme protein MIC4 0.0031 0.0047 0.0075
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.006 0.0097
Plasmodium vivax vivapain-2 0.1156 0.3805 1
Brugia malayi Cell death protein 3 precursor 0.0159 0.0474 0.0471
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0504 0.05
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0034 0.0057 0.0094
Schistosoma mansoni ran 0.0026 0.0029 0.0025
Plasmodium vivax SET domain protein, putative 0.0096 0.0264 0.0683
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0018 0.0014
Plasmodium falciparum centrin-1 0.014 0.041 0.1068
Toxoplasma gondii aspartyl protease ASP1 0.0042 0.0082 0.0137
Giardia lamblia Hypothetical protein 0.0282 0.0886 0.2359
Toxoplasma gondii prolyl endopeptidase 0.1729 0.5721 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Plasmodium vivax proteasome subunit beta type-7, putative 0.0034 0.0057 0.0141
Leishmania major GTP-binding protein, putative 0.0026 0.0029 0.0044
Plasmodium vivax histone deacetylase, putative 0.0044 0.0089 0.0223
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1156 0.3805 1
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0084 0.0223 0.0219
Trypanosoma brucei calmodulin, putative 0.0142 0.0418 0.0724
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0034 0.0057 0.0141
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0042 0.0082 0.0078
Brugia malayi Proteasome A-type and B-type family protein 0.0034 0.0057 0.0054
Schistosoma mansoni Mername-AA248 (C02 family) 0.0875 0.2868 0.2865
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.301 1 1
Trypanosoma brucei Calpain-like protein 1.2 0.0257 0.0803 0.1398
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0022 0.0016 0.0031
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0282 0.0886 0.0882
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1156 0.3805 0.3803
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0208 0.0637 0.0634
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0282 0.0886 0.232
Echinococcus multilocularis glycogen phosphorylase 0.0111 0.0314 0.031
Echinococcus multilocularis EF HAND 1, calcium binding site 0.014 0.041 0.0406
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0043 0.0086 0.0082
Trypanosoma brucei histone deacetylase, putative 0.0101 0.0282 0.0487
Onchocerca volvulus Cathepsin L homolog 0.1156 0.3805 0.6651
Echinococcus granulosus centrin 2 0.014 0.041 0.0406
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0029 0.0044
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0072 0.0068
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.0803 0.08
Onchocerca volvulus Chorion peroxidase homolog 0.0168 0.0504 0.0881
Echinococcus granulosus importin subunit beta 1 0.0035 0.006 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0886 0.232
Toxoplasma gondii histone deacetylase HDAC3 0.009 0.0245 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0637 0.1667
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0018 0.0014
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0282 0.0886 0.2359
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0282 0.0886 0.232
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0012
Leishmania major histone deacetylase, putative 0.009 0.0245 0.0422
Brugia malayi Trypsin family protein 0.0141 0.0413 0.041
Schistosoma mansoni caspase-7 (C14 family) 0.0159 0.0474 0.0471
Schistosoma mansoni hypothetical protein 0.014 0.041 0.0406
Echinococcus multilocularis cpg binding protein 0.0032 0.0051 0.0048
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0636 0.2069 0.2066
Echinococcus multilocularis hypothetical protein 0.0875 0.2868 0.2865
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0034 0.0057 0.0054
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.014 0.041 0.0406
Brugia malayi Cathepsin L-like precursor 0.0802 0.2622 0.2619
Trypanosoma brucei centrin-3 0.0143 0.0422 0.0731
Brugia malayi RNA, U transporter 1 0.0099 0.0274 0.027
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0141 0.0413 0.041
Brugia malayi Proteasome subunit alpha type 1 0.0034 0.0057 0.0054
Leishmania major proteasome alpha 7 subunit, putative 0.0034 0.0057 0.0094
Onchocerca volvulus 0.0055 0.0128 0.0224
Giardia lamblia Hypothetical protein 0.0142 0.0418 0.1091
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0042 0.0082 0.0137
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0034 0.0057 0.0094
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0061 0.0058
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0064 0.0014
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2474 0.8209 0.8208
Onchocerca volvulus 0.1156 0.3805 0.6651
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0034 0.0057 0.0094
Entamoeba histolytica cysteine proteinase, putative 0.0802 0.2622 0.6877
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Echinococcus granulosus expressed protein 0.0834 0.2731 0.2728
Onchocerca volvulus 0.0031 0.0047 0.0081
Leishmania major hypothetical protein, unknown function 0.0257 0.0803 0.1398
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0282 0.0886 0.232
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0086 0.0217
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Echinococcus granulosus gamma secretase subunit aph 1 0.0257 0.0802 0.0798
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0034 0.0057 0.0141
Leishmania major cathepsin L-like protease 0.1261 0.4156 0.7264
Plasmodium vivax calpain, putative 0.0875 0.2868 0.7535
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0418 0.1089
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.0022 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.1261 0.4156 0.4154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0018 0.0014
Echinococcus multilocularis expressed protein 0.0834 0.2731 0.2728
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.0245 0.0634
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0082
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0018 0.0014
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Loa Loa (eye worm) histone deacetylase 11 0.0044 0.0089 0.0085
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0034 0.0057 0.0094
Echinococcus multilocularis proteasome (prosome, macropain) 0.0174 0.0525 0.0521
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0034 0.0057 0.011
Plasmodium falciparum serine repeat antigen 7 0.0282 0.0886 0.232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0034 0.0057 0.0094
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0018 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0064 0.0014
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0034 0.0057 0.0054
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0404 0.1292 0.1288
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0072 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0637 0.0634
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0038 0.0088
Entamoeba histolytica hypothetical protein 0.0043 0.0086 0.0187
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0057 0.0141
Schistosoma mansoni histone deacetylase 4 5 0.0101 0.0282 0.0278
Echinococcus granulosus calmodulin 0.014 0.041 0.0406
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0023
Giardia lamblia Cathepsin B precursor 0.0282 0.0886 0.2359
Mycobacterium ulcerans zinc metalloprotease 0.0096 0.0265 0.0926
Leishmania major proteasome beta 2 subunit, putative 0.0034 0.0057 0.0094
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0354 0.1127 0.1123
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0245 0.0634
Onchocerca volvulus 0.0031 0.0047 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0061 0.0058
Giardia lamblia 20S proteasome alpha subunit 6 0.0034 0.0057 0.0113
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0047 0.0075
Loa Loa (eye worm) hypothetical protein 0.009 0.0245 0.0241
Toxoplasma gondii aspartyl protease ASP3 0.0202 0.0617 0.1073
Leishmania major programmed cell death 6 protein-like protein 0.014 0.041 0.071
Brugia malayi histone deacetylase 3 (HD3) 0.009 0.0245 0.0241
Echinococcus granulosus subfamily T1A non peptidase ue 0.0034 0.0057 0.0054
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0064 0.006
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.0282 0.0278
Loa Loa (eye worm) hypothetical protein 0.0073 0.0187 0.0183
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0096 0.0265 0.0261
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.0803 0.1398
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0018 0.0014
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Leishmania major calmodulin-like protein 0.014 0.041 0.071
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0034 0.0057 0.0054
Toxoplasma gondii aspartyl protease 0.0042 0.0082 0.0137
Schistosoma mansoni microtubule-associated protein tau 0.1526 0.504 0.5038
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.041
Giardia lamblia Cathepsin L precursor 0.0282 0.0886 0.2359
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1156 0.3805 0.3803
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0018 0.0014
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.014 0.041 0.071
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.2865
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0022 0.0016 0.0012
Onchocerca volvulus 0.0048 0.0103 0.018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Brugia malayi histone deacetylase 11 0.0044 0.0089 0.0085
Entamoeba histolytica cysteine proteinase, putative 0.1156 0.3805 1
Trypanosoma brucei histone deacetylase 3 0.0101 0.0282 0.0487
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0086 0.0217
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0023
Onchocerca volvulus Peroxidasin homolog 0.0168 0.0504 0.0881
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0034 0.0057 0.011
Entamoeba histolytica glycogenphosphorylase, putative 0.0048 0.0103 0.0232
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0082
Leishmania major calmodulin-like protein 0.014 0.041 0.071
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0637 0.0634
Giardia lamblia Cathepsin B precursor 0.0282 0.0886 0.2359
Echinococcus granulosus proteasome subunit beta type 6 0.0034 0.0057 0.0054
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0072 0.0178
Brugia malayi A-kinase anchor protein 10, precursor 0.0043 0.0086 0.0082
Schistosoma mansoni calpain (C02 family) 0.0875 0.2868 0.2865
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.026 0.0256
Plasmodium vivax unspecified product 0.0282 0.0886 0.232
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0086 0.0082
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0022 0.0018
Echinococcus granulosus caspase 8 0.0018 0.0004 0.000000019489
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0034 0.0057 0.0141
Loa Loa (eye worm) EF hand family protein 0.014 0.041 0.0406
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1126 0.3705 0.3702
Echinococcus multilocularis calpain 5 0.0875 0.2868 0.2865
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0034 0.0057 0.0113
Schistosoma mansoni neprilysin 0.0025 0.0027 0.0023
Loa Loa (eye worm) histone deacetylase 0.0101 0.0282 0.0278
Leishmania major histone deacetylase, putative 0.009 0.0245 0.0422
Brugia malayi Calmodulin-like protein 0.014 0.041 0.0406
Onchocerca volvulus 0.0142 0.0418 0.0731
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.041
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Mycobacterium leprae Probable lipase LipE 0.0036 0.0064 0.003
Echinococcus multilocularis EF hand domain containing family member A2 0.0142 0.0418 0.0414
Brugia malayi Thioredoxin family protein 0.0284 0.0891 0.0887
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0208 0.0637 0.0634
Entamoeba histolytica calmodulin, putative 0.014 0.041 0.1041
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0034 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0043
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0072 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Plasmodium falciparum histone deacetylase, putative 0.0101 0.0282 0.0732
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.026 0.0256
Brugia malayi cathepsin L precursor 0.0282 0.0886 0.0882
Onchocerca volvulus Prolyl endopeptidase homolog 0.1729 0.5721 1
Toxoplasma gondii microneme protein MIC17B 0.0031 0.0047 0.0075
Trichomonas vaginalis calmodulin, putative 0.014 0.041 0.1068
Plasmodium vivax aspartyl protease, putative 0.0202 0.0617 0.1614
Trypanosoma cruzi histone deacetylase, putative 0.0044 0.0089 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0886 0.232
Trichomonas vaginalis conserved hypothetical protein 0.014 0.041 0.1068
Echinococcus granulosus beta-adrenergic receptor kinase 0.0043 0.0086 0.0082
Schistosoma mansoni cathepsin F (C01 family) 0.1156 0.3805 0.3803
Leishmania major proteasome alpha 7 subunit, putative 0.0034 0.0057 0.0094
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0135 0.0395 0.1029
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0086 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0022 0.0016 0.0012
Brugia malayi prolyl oligopeptidase family protein 0.1729 0.5721 0.5719
Trypanosoma brucei proteasome beta 6 subunit 0.0135 0.0395 0.0684
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0282 0.0886 0.232
Echinococcus multilocularis cathepsin b 0.301 1 1
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0034 0.0057 0.0054
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0072 0.0152
Trypanosoma cruzi oligopeptidase b 0.0705 0.23 0.2297
Brugia malayi hypothetical protein 0.0141 0.0414 0.041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.501
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0016 0.0031
Echinococcus multilocularis cathepsin L cysteine protease 0.1156 0.3805 0.3803
Entamoeba histolytica calpain family cysteine protease, putative 0.0257 0.0803 0.2078
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0072 0.0118
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0043 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1126 0.3705 0.3702
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0282 0.0886 0.232
Echinococcus multilocularis Mastin 0.0141 0.0413 0.041
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0029 0.0066
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0018 0.0014
Onchocerca volvulus 0.0031 0.0047 0.0081
Giardia lamblia Cathepsin B precursor 0.1126 0.3705 1
Schistosoma mansoni peroxidasin 0.0168 0.0504 0.05
Echinococcus granulosus calbindin 32 0.0142 0.0418 0.0414
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0018 0.0014
Schistosoma mansoni cpg binding protein 0.0031 0.0046 0.0042
Leishmania major cathepsin L-like protease 0.1261 0.4156 0.7264
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0264 0.026
Echinococcus multilocularis prolyl endopeptidase 0.1729 0.5721 0.5719
Onchocerca volvulus 0.1156 0.3805 0.6651
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0174 0.0525 0.2083
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0142 0.0418 0.0414
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0264 0.026
Giardia lamblia Histone deacetylase 0.009 0.0245 0.0622
Echinococcus multilocularis inhibitor of apoptosis protein 0.0188 0.0572 0.0568
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0875 0.2868 0.2865
Echinococcus granulosus histone deacetylase 8 0.0044 0.0089 0.0085
Plasmodium falciparum importin beta, putative 0.0035 0.006 0.0146
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0034 0.0057 0.0094
Loa Loa (eye worm) blistered cuticle protein 3 0.0168 0.0504 0.05
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0504 0.05
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0018 0.0014
Echinococcus granulosus caspase 2 0.0159 0.0474 0.0471
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0282 0.0886 0.232
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.026 0.0256
Toxoplasma gondii calmodulin CAM1 0.0142 0.0418 0.0724
Echinococcus multilocularis histone deacetylase 0.0101 0.0282 0.0278
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0018 0.0014
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0034 0.0057 0.0054
Toxoplasma gondii subtilisin SUB12 0.0031 0.0047 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.256 0.8496 0.8495
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0135 0.0395 0.1029
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0705 0.23 0.2297
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.014 0.041 0.1041
Schistosoma mansoni histone deacetylase hda2 0.0044 0.0089 0.0085
Plasmodium vivax histone deacetylase 2, putative 0.0101 0.0282 0.0732
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.014 0.041 0.0406
Brugia malayi beta-lactamase family protein 0.0036 0.0064 0.006
Toxoplasma gondii exonuclease III APE 0.0038 0.0072 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0018 0.0014
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0174 0.0525 0.137
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.0082 0.0206
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0047 0.0043
Trichomonas vaginalis esterase, putative 0.0036 0.0064 0.0159
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Toxoplasma gondii EF hand domain-containing protein 0.014 0.041 0.071
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Schistosoma mansoni cathepsin B (C01 family) 0.0282 0.0886 0.0882
Leishmania major proteasome beta 2 subunit, putative 0.0084 0.0223 0.0383
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0029 0.0025
Echinococcus multilocularis histone deacetylase 1 0.009 0.0245 0.0241
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.006
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0875 0.2868 0.2865
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0064 0.006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0034 0.0057 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0034 0.0057 0.011
Loa Loa (eye worm) calpain family protein 1 0.1716 0.5677 0.5675
Brugia malayi Papain family cysteine protease containing protein 0.0282 0.0886 0.0882
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0018 0.0014
Leishmania major histone deacetylase, putative 0.0101 0.0282 0.0487
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0034 0.0057 0.0054
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Brugia malayi calpain D 0.0257 0.0803 0.08
Brugia malayi Angiotensin-converting enzyme family protein 0.256 0.8496 0.8495
Toxoplasma gondii cathepsin CPC1 0.0282 0.0886 0.1542
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0282 0.0886 0.232
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0022 0.0016 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0802 0.2622 0.6886
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0072 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.003 0.0045
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0084 0.0223 0.0547
Onchocerca volvulus 0.0042 0.0082 0.0144
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.0803 0.08
Brugia malayi Cytochrome P450 family protein 0.0058 0.0139 0.0135
Brugia malayi prolyl oligopeptidase family protein 0.0208 0.0637 0.0634
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0018 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0018 0.0014
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1729 0.5721 0.5719
Echinococcus multilocularis neurocalcin 0.014 0.041 0.0406
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0282 0.0886 0.2359
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0049 0.0106 0.0102
Echinococcus multilocularis cathepsin b 0.301 1 1
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0034 0.0057 0.0054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0264 0.026
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0064 0.006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0029 0.0025
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0038 0.0088
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0354 0.035
Onchocerca volvulus 0.0031 0.0047 0.0081
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0504 0.05
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0264 0.026
Schistosoma mansoni calpain C (C02 family) 0.0875 0.2868 0.2865
Echinococcus granulosus EF hand domain containing family member A2 0.0142 0.0418 0.0414
Trypanosoma cruzi cysteine protease, putative 0.0636 0.2069 0.2066
Loa Loa (eye worm) aspartyl protease 6 0.0042 0.0082 0.0078
Onchocerca volvulus 0.1156 0.3805 0.6651
Schistosoma mansoni glycogen phosphorylase 0.0111 0.0314 0.031
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0303 0.0957 0.0953
Giardia lamblia Cathepsin B precursor 0.0282 0.0886 0.2359
Trichomonas vaginalis calmodulin, putative 0.0142 0.0418 0.1089
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Mycobacterium tuberculosis Conserved protein 0.0036 0.0064 0.0014
Plasmodium falciparum peptidase, putative 0.0208 0.0637 0.1667
Loa Loa (eye worm) histone deacetylase 3 0.009 0.0245 0.0241
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0072 0.0178
Loa Loa (eye worm) hypothetical protein 0.0159 0.0474 0.0471
Echinococcus multilocularis programmed cell death protein 0.0143 0.0422 0.0418
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0018 0.0014
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0047 0.0075
Schistosoma mansoni hypothetical protein 0.0372 0.1185 0.1182
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0018 0.0014
Brugia malayi Cathepsin L-like cysteine proteinase 0.0802 0.2622 0.2619
Trypanosoma cruzi kinesin, putative 0.0618 0.2008 0.2005
Plasmodium vivax histone deacetylase 1, putative 0.009 0.0245 0.0634
Trypanosoma brucei calpain-like protein, putative 0.0875 0.2868 0.501
Loa Loa (eye worm) hypothetical protein 0.0208 0.0637 0.0634
Onchocerca volvulus 0.0036 0.0064 0.0112
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0705 0.23 0.4017
Trichomonas vaginalis centrin, putative 0.014 0.041 0.1068
Onchocerca volvulus Deterin homolog 0.0188 0.0572 0.0999
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0282 0.0886 0.0882
Giardia lamblia 20S proteasome alpha subunit 7 0.0034 0.0057 0.0113
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0018 0.0014
Plasmodium vivax proteasome subunit beta type-1, putative 0.0135 0.0395 0.1029
Echinococcus multilocularis neuronal calcium sensor 0.014 0.041 0.0406
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Loa Loa (eye worm) hypothetical protein 0.0073 0.0187 0.0183
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0141 0.0413 0.041
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.014 0.041 0.0406
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0705 0.23 0.4017
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.055 0.1782 0.1779
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0504 0.05
Echinococcus granulosus Mastin 0.0141 0.0413 0.041
Loa Loa (eye worm) proteasome subunit beta type 3 0.0034 0.0057 0.0054
Leishmania major proteasome beta 7 subunit, putative 0.0034 0.0057 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0018 0.0014
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0072 0.0068
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.014 0.041 0.1068
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0257 0.0803 0.2103
Onchocerca volvulus 0.1156 0.3805 0.6651
Brugia malayi Proteasome subunit alpha type 7-1 0.0034 0.0057 0.0054
Brugia malayi hypothetical protein 0.0261 0.0816 0.0812
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0034 0.0057 0.0141
Echinococcus granulosus cysteine protease 0.0636 0.2069 0.2066
Brugia malayi Cathepsin L-like precursor 0.1156 0.3805 0.3803
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0034 0.0057 0.0054
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0389 0.0667
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0018 0.0014
Onchocerca volvulus 0.0141 0.0413 0.0723
Echinococcus granulosus cathepsin l1 0.0802 0.2622 0.2619
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Trypanosoma brucei hypothetical protein 0.0257 0.0803 0.1398
Entamoeba histolytica hypothetical protein 0.0043 0.0086 0.0187
Leishmania major cysteine peptidase A (CPA) 0.1156 0.3805 0.6649
Leishmania major proteasome beta 3 subunit, putative 0.0034 0.0057 0.0094
Onchocerca volvulus 0.0031 0.0047 0.0081
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0504 0.05
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0064 0.003
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0303 0.0957 0.1667
Plasmodium falciparum cysteine repeat modular protein 1 0.0048 0.0103 0.0261
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Giardia lamblia 20S proteasome alpha subunit 4 0.0034 0.0057 0.0113
Echinococcus granulosus calpain 0.0875 0.2868 0.2865
Echinococcus granulosus endothelin converting enzyme 1 0.0096 0.0265 0.0261
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0282 0.0886 0.2296
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0064 0.003
Echinococcus granulosus histone deacetylase 7 0.0101 0.0282 0.0278
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0875 0.2868 0.2865
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0034 0.0057 0.0054
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0034 0.0057 0.011
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0174 0.0525 0.0911
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0034 0.0057 0.0141
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.041
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0072 0.0068
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0043 0.0086 0.0082
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0135 0.0395 0.0391
Trypanosoma cruzi I/6 autoantigen, putative 0.014 0.041 0.0406
Schistosoma mansoni hypothetical protein 0.0141 0.0414 0.041
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0034 0.0057 0.011
Schistosoma mansoni cathepsin S (C01 family) 0.0282 0.0886 0.0882
Trichomonas vaginalis calmodulin, putative 0.014 0.041 0.1068
Brugia malayi Serine carboxypeptidase S28 family protein 0.0022 0.0016 0.0012
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0034 0.0057 0.0094
Entamoeba histolytica prolyl oligopeptidase family protein 0.0208 0.0637 0.1641
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0057 0.0141
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0282 0.0886 0.232
Schistosoma mansoni cathepsin F (C01 family) 0.1156 0.3805 0.3803
Toxoplasma gondii proteasome beta subunit 0.0034 0.0057 0.0094
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.003 0.0026
Plasmodium vivax unspecified product 0.0636 0.2069 0.5433
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0404 0.1292 0.1288
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0043 0.0086 0.0217
Echinococcus multilocularis snurportin 1 0.0372 0.1185 0.1182
Brugia malayi cathepsin L-like cysteine proteinase 0.0282 0.0886 0.0882
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0282 0.0886 0.232
Onchocerca volvulus 0.0168 0.0504 0.0881
Onchocerca volvulus Glycogen phosphorylase homolog 0.0111 0.0314 0.0549
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0064 0.003
Giardia lamblia Proteasome subunit beta type 1 0.0135 0.0395 0.1028
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0034 0.0057 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0257 0.0803 0.2103
Brugia malayi CXXC zinc finger family protein 0.0031 0.0046 0.0042
Onchocerca volvulus 0.0031 0.0047 0.0081
Trypanosoma brucei Component of motile flagella 41 0.014 0.041 0.071
Onchocerca volvulus 0.0022 0.0018 0.0031
Trypanosoma brucei prolyl endopeptidase 0.1729 0.5721 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0282 0.0886 0.0882
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0084 0.0223 0.0577
Schistosoma mansoni neuronal calcium sensor 0.014 0.041 0.0406
Trypanosoma cruzi calmodulin, putative 0.014 0.041 0.0406
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0886 0.232
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.301 1 1
Schistosoma mansoni centrin-related 0.014 0.041 0.0406
Entamoeba histolytica cysteine proteinase, putative 0.0636 0.2069 0.5419
Leishmania major cathepsin L-like protease 0.1156 0.3805 0.6649
Entamoeba histolytica calcium binding family protein 0.014 0.041 0.1041
Trypanosoma cruzi cysteine proteinase, putative 0.0636 0.2069 0.2066
Brugia malayi beta-lactamase family protein 0.0036 0.0064 0.006
Trypanosoma brucei centrin, putative 0.014 0.041 0.071
Mycobacterium tuberculosis Conserved hypothetical protein 0.0284 0.0891 0.1677
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0061 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Mycobacterium tuberculosis Conserved protein 0.0036 0.0064 0.0014
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0034 0.0057 0.0054
Onchocerca volvulus 0.0141 0.0413 0.0723
Trichomonas vaginalis conserved hypothetical protein 0.0282 0.0886 0.232
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0072 0.0068
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.014 0.041 0.1041
Entamoeba histolytica cysteine protease, putative 0.0282 0.0886 0.2296
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0034 0.0057 0.0054
Trypanosoma brucei proteasome alpha 7 subunit 0.0034 0.0057 0.0094
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0082
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0043 0.0086 0.0082
Echinococcus multilocularis histone deacetylase 6 0.0101 0.0282 0.0278
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0034 0.0057 0.0141
Loa Loa (eye worm) hypothetical protein 0.0096 0.0265 0.0261
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.014 0.041 0.1068
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0084 0.0223 0.0219
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0282 0.0886 0.0882
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0029 0.0025
Trichomonas vaginalis calcium binding protein, putative 0.014 0.041 0.1068
Toxoplasma gondii cathepsin B 0.1126 0.3705 0.6473
Loa Loa (eye worm) hypothetical protein 0.0048 0.0103 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.501
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0042 0.0082 0.0137
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0018 0.0014
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0135 0.0395 0.0684
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0064 0.0106
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.501
Echinococcus multilocularis proteasome subunit alpha type 2 0.0034 0.0057 0.0054
Onchocerca volvulus 0.1156 0.3805 0.6651
Plasmodium vivax aspartyl protease, putative 0.0202 0.0617 0.1614
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0208 0.0637 0.1641
Brugia malayi proteasome subunit beta type 1 0.0135 0.0395 0.0391
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0034 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0073 0.0187 0.0183
Echinococcus multilocularis caspase 8 0.0018 0.0004 0.000000019489
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0061 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1261 0.4156 0.7264
Echinococcus multilocularis apoptotic protease activating factor 1 0.0141 0.0414 0.041
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0034 0.0057 0.0054
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0135 0.0395 0.0391
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0264 0.026
Entamoeba histolytica Flap nuclease, putative 0.0026 0.003 0.0037
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.501
Brugia malayi Papain family cysteine protease containing protein 0.1156 0.3805 0.3803
Giardia lamblia Alanyl dipeptidyl peptidase 0.0208 0.0637 0.1685
Echinococcus granulosus enteropeptidase 0.0141 0.0413 0.041
Loa Loa (eye worm) histone deacetylase 7A 0.0101 0.0282 0.0278
Trichomonas vaginalis peptide N-glycanase, putative 0.0284 0.0891 0.2333
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.041
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Brugia malayi proteasome subunit beta type 3 0.0034 0.0057 0.0054
Schistosoma mansoni cathepsin C 0.0282 0.0886 0.0882
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0181 0.0177
Plasmodium falciparum serine repeat antigen 5 0.0282 0.0886 0.232
Schistosoma mansoni hypothetical protein 0.0284 0.0891 0.0887
Giardia lamblia Cysteine protease 0.0282 0.0886 0.2359
Toxoplasma gondii hypothetical protein 0.0031 0.0047 0.0075
Brugia malayi gamma-secretase subunit aph-1 0.0257 0.0802 0.0798
Trypanosoma brucei histone deacetylase 1 0.009 0.0245 0.0422
Plasmodium vivax vivapain-1 0.0636 0.2069 0.5433
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0504 0.05
Echinococcus multilocularis proteasome subunit beta type 7 0.0034 0.0057 0.0054
Brugia malayi hypothetical protein 0.0096 0.0263 0.0259
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0084 0.0223 0.0219
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0034 0.0057 0.0054
Schistosoma mansoni cathepsin F (C01 family) 0.0802 0.2622 0.2619
Schistosoma mansoni mitochondrial solute carrier 0.014 0.041 0.0406
Loa Loa (eye worm) calmodulin-like protein 0.014 0.041 0.0406
Giardia lamblia 20S proteasome alpha subunit 2 0.0034 0.0057 0.0113
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0086 0.0082
Echinococcus multilocularis glycogen phosphorylase 0.0111 0.0314 0.031
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.006
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.301 1 1
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0018 0.0014
Plasmodium vivax aspartyl protease, putative 0.0042 0.0082 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0086 0.0217
Entamoeba histolytica cysteine protease, putative 0.0282 0.0886 0.2296
Onchocerca volvulus Notchless protein homolog 0.0034 0.0057 0.01
Mycobacterium leprae Conserved hypothetical protein 0.0284 0.0891 0.3715
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Echinococcus granulosus sarcoplasmic calcium binding protein 0.014 0.041 0.0406
Loa Loa (eye worm) hypothetical protein 0.0044 0.0089 0.0085
Brugia malayi Pepsin A precursor 0.0042 0.0082 0.0078
Echinococcus multilocularis flap endonuclease 1 0.0026 0.003 0.0026
Trypanosoma cruzi cysteine peptidase, putative 0.1261 0.4156 0.4154
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0034 0.0057 0.0054
Onchocerca volvulus 0.0141 0.0414 0.0723
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0282 0.0886 0.232
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0086 0.0082
Onchocerca volvulus 0.0757 0.2471 0.432
Trichomonas vaginalis myosin light chain 1, putative 0.014 0.041 0.1068
Echinococcus granulosus calumenin 0.0142 0.0418 0.0414
Brugia malayi Trypsin family protein 0.0141 0.0413 0.041
Loa Loa (eye worm) PXA domain-containing protein 0.0043 0.0086 0.0082
Echinococcus multilocularis Transglutaminase 0.0284 0.0891 0.0887
Brugia malayi Histone deacetylase family protein 0.0101 0.0282 0.0278
Loa Loa (eye worm) hypothetical protein 0.0096 0.0264 0.026
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0064 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.026 0.0256
Toxoplasma gondii hypothetical protein 0.0257 0.0803 0.1398
Toxoplasma gondii centrin, putative 0.014 0.041 0.071
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0034 0.0057 0.0094
Onchocerca volvulus Cathepsin L homolog 0.1156 0.3805 0.6651
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0034 0.0057 0.0141
Onchocerca volvulus 0.0802 0.2622 0.4583
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0264 0.026
Echinococcus multilocularis gamma secretase subunit aph 1 0.0257 0.0802 0.0798
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0064 0.0014
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0047 0.0075
Leishmania major i/6 autoantigen-like protein 0.014 0.041 0.071
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0636 0.2069 0.2066
Entamoeba histolytica hypothetical protein 0.0282 0.0886 0.2296
Toxoplasma gondii kringle domain-containing protein 0.0048 0.0103 0.0174
Schistosoma mansoni cathepsin s 0.0354 0.1127 0.1123
Onchocerca volvulus 0.0031 0.0047 0.0081
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0174 0.0525 0.0521
Toxoplasma gondii centrin 0.014 0.041 0.071
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.2865
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0034 0.0057 0.0054
Trypanosoma brucei cysteine peptidase C (CPC) 0.1126 0.3705 0.6473
Trichomonas vaginalis calpain, putative 0.0257 0.0803 0.2103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0636 0.2069 0.5433
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0064 0.0159
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.014 0.041 0.0406
Leishmania major proteasome alpha 1 subunit, putative 0.0034 0.0057 0.0094
Trypanosoma brucei Calpain-like protein 2 0.0257 0.0803 0.1398
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1156 0.3805 0.3803
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0034 0.0057 0.0113
Echinococcus granulosus EF hand domain containing family member A2 0.014 0.041 0.0406
Giardia lamblia Cathepsin B precursor 0.0282 0.0886 0.2359
Trypanosoma brucei proteasome beta 7 subunit 0.0034 0.0057 0.0094
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0188 0.0572 0.0568
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0023
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0245 0.0634
Giardia lamblia Transglutaminase/protease, putative 0.0284 0.0891 0.2372
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0257 0.0802 0.0798
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0034 0.0057 0.0054
Mycobacterium leprae Conserved hypothetical protein 0.0284 0.0891 0.3715
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0899 0.2948 0.2945
Brugia malayi hypothetical protein 0.0042 0.0082 0.0078
Giardia lamblia Cathepsin L-like protease 0.0282 0.0886 0.2359
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0086 0.0082
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Mycobacterium tuberculosis Conserved protein 0.0036 0.0064 0.0014
Giardia lamblia Cathepsin L precursor 0.0282 0.0886 0.2359
Echinococcus granulosus calpain 5 0.0875 0.2868 0.2865
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Plasmodium vivax serine-repeat antigen (SERA) 0.0282 0.0886 0.232
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Plasmodium falciparum serine repeat antigen 1 0.0282 0.0886 0.232
Plasmodium falciparum plasmepsin VII 0.0042 0.0082 0.0206
Onchocerca volvulus 0.0096 0.0264 0.0461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0636 0.2069 0.5433
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Brugia malayi PAN domain containing protein 0.0031 0.0047 0.0043
Loa Loa (eye worm) glycogen phosphorylase 0.0111 0.0314 0.031
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0029 0.0025
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0149 0.0254
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.1402 0.1399
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0282 0.0886 0.0882
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0282 0.0886 0.232
Chlamydia trachomatis glycogen phosphorylase 0.0111 0.0314 0.5
Schistosoma mansoni calpain-7 (C02 family) 0.0878 0.2878 0.2875
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0018 0.0031
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1156 0.3805 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1156 0.3805 1
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0034 0.0057 0.0113
Schistosoma mansoni hypothetical protein 0.0164 0.049 0.0486
Leishmania major oligopeptidase b 0.0705 0.23 0.4017
Echinococcus granulosus histone deacetylase 1 0.009 0.0245 0.0241
Echinococcus multilocularis histone deacetylase 7 0.0101 0.0282 0.0278
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0043
Entamoeba histolytica grainin 2 0.0143 0.0422 0.1072
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0034 0.0057 0.011
Toxoplasma gondii proteasome subunit 0.0034 0.0057 0.0094
Loa Loa (eye worm) hypothetical protein 0.0073 0.0187 0.0183
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0018 0.0014
Echinococcus granulosus peroxidasin 0.0168 0.0504 0.05
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0282 0.0886 0.0882
Entamoeba histolytica prolyl oligopeptidase family protein 0.0208 0.0637 0.1641
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.08
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1156 0.3805 1
Mycobacterium ulcerans hypothetical protein 0.0141 0.0413 0.1587
Loa Loa (eye worm) ctsf protein 0.1156 0.3805 0.3803
Trypanosoma brucei histone deacetylase 4 0.0101 0.0282 0.0487
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0875 0.2868 0.2865
Brugia malayi calpain family protein 1 0.2334 0.7742 0.7741
Trypanosoma brucei hypothetical protein, conserved 0.014 0.041 0.071
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0086 0.0082
Toxoplasma gondii cathepsin CPL 0.1156 0.3805 0.6649
Schistosoma mansoni hypothetical protein 0.0188 0.0572 0.0568
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Schistosoma mansoni flap endonuclease-1 0.0023 0.0021 0.0017
Leishmania major phospholipase c-like protein 0.014 0.041 0.071
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0086 0.0082
Echinococcus granulosus tumor protein p63 0.0378 0.1205 0.1201
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0057 0.0094
Leishmania major cytochrome p450-like protein 0.0035 0.0061 0.0101
Onchocerca volvulus Cathepsin L homolog 0.0282 0.0886 0.1548
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0061 0.0101
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0282 0.0886 0.232
Brugia malayi Cytochrome P450 family protein 0.0035 0.0061 0.0058
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0042 0.0082 0.0078
Brugia malayi Proteasome A-type and B-type family protein 0.0034 0.0057 0.0054
Leishmania major centrin, putative,caltractin, putative 0.014 0.041 0.071
Loa Loa (eye worm) hypothetical protein 0.0282 0.0886 0.0882
Echinococcus granulosus cathepsin L cysteine proteinase 0.1156 0.3805 0.3803
Loa Loa (eye worm) programmed cell death protein 6 0.0142 0.0418 0.0414
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0086 0.0082
Schistosoma mansoni reticulocalbin 0.014 0.041 0.0406
Brugia malayi Peroxidasin 0.0168 0.0504 0.05
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0042 0.0082 0.0078
Schistosoma mansoni hypothetical protein 0.0437 0.1402 0.1399
Echinococcus multilocularis acylamino acid releasing enzyme 0.0208 0.0637 0.0634
Brugia malayi Trypsin-like protease protein 5 0.0141 0.0413 0.041
Toxoplasma gondii hypothetical protein 0.0031 0.0047 0.0075
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.014 0.041 0.0406
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0135 0.0395 0.0391
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0034 0.0057 0.0094
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0034 0.0057 0.0054
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0016 0.0031
Brugia malayi prolyl oligopeptidase family protein 0.055 0.1782 0.1779
Brugia malayi Serine protease Z688.6 precursor 0.0022 0.0016 0.0012
Loa Loa (eye worm) calpain family protein 1 0.2334 0.7742 0.7741
Leishmania major importin beta-1 subunit, putative 0.0028 0.0038 0.0059
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0303 0.0957 0.1667
Brugia malayi Blistered cuticle protein 3 0.0168 0.0504 0.05
Brugia malayi hypothetical protein 0.0043 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0071 0.0181 0.0177
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0257 0.0803 0.1398
Echinococcus granulosus cathepsin L cysteine protease 0.0636 0.2069 0.2066
Trypanosoma cruzi cysteine peptidase, putative 0.1261 0.4156 0.4154
Trypanosoma brucei mitochondrial calcium uptake 1 0.014 0.041 0.071
Echinococcus granulosus glycogen phosphorylase 0.0111 0.0314 0.031
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0034 0.0057 0.0141
Giardia lamblia Cathepsin B precursor 0.1126 0.3705 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0354 0.1127 0.1123
Plasmodium falciparum plasmepsin V 0.0042 0.0082 0.0206
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0257 0.0803 0.08
Onchocerca volvulus 0.1459 0.4817 0.842
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0018 0.0014
Onchocerca volvulus 0.0053 0.0121 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0082 0.0078
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Echinococcus granulosus cathepsin b 0.301 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0018 0.0014
Schistosoma mansoni survival motor neuron protein 0.0053 0.0121 0.0117
Toxoplasma gondii heat shock protein hslv, putative 0.0034 0.0057 0.0094
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0803 0.1398
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0282 0.0886 0.0882
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.014 0.041 0.0406
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1156 0.3805 1
Loa Loa (eye worm) hypothetical protein 0.014 0.041 0.0406
Giardia lamblia Cathepsin L-like protease 0.0282 0.0886 0.2359
Loa Loa (eye worm) hypothetical protein 0.0354 0.1127 0.1123
Trypanosoma cruzi cysteine peptidase, putative 0.0354 0.1127 0.1123
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0029 0.0036
Brugia malayi cathepsin F-like cysteine proteinase 0.0354 0.1127 0.1123
Onchocerca volvulus 0.0036 0.0064 0.0112
Echinococcus granulosus geminin 0.0164 0.049 0.0486
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0014
Schistosoma mansoni neuronal calcium sensor 0.014 0.041 0.0406
Entamoeba histolytica cysteine protease, putative 0.0636 0.2069 0.5419
Trypanosoma cruzi calmodulin, putative 0.014 0.041 0.0406
Schistosoma mansoni cpg binding protein 0.0032 0.0051 0.0048
Plasmodium falciparum plasmepsin IX 0.0202 0.0617 0.1614
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0188 0.0572 0.0568
Loa Loa (eye worm) hypothetical protein 0.0168 0.0504 0.05
Loa Loa (eye worm) hypothetical protein 0.0141 0.0413 0.041
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0174 0.0525 0.0521
Echinococcus multilocularis cathepsin L 0.0636 0.2069 0.2066
Entamoeba histolytica hypothetical protein, conserved 0.0208 0.0637 0.1641
Echinococcus multilocularis histone deacetylase 6 0.0108 0.0303 0.03
Trypanosoma brucei cysteine peptidase, putative 0.0257 0.0803 0.1398
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0047 0.0043
Trichomonas vaginalis calcineurin B subunit, putative 0.014 0.041 0.1068
Trichomonas vaginalis glycogen phosphorylase, putative 0.0111 0.0314 0.0816
Trichomonas vaginalis calpain, putative 0.0257 0.0803 0.2103
Loa Loa (eye worm) calpain 0.0875 0.2868 0.2865
Giardia lamblia Encystation-specific protease 0.0282 0.0886 0.2359
Onchocerca volvulus Histone deacetylase 10 homolog 0.0044 0.0089 0.0155
Loa Loa (eye worm) hypothetical protein 0.0282 0.0886 0.0882
Brugia malayi programmed cell death protein 6 0.014 0.041 0.0406
Onchocerca volvulus 0.0031 0.0047 0.0081
Trichomonas vaginalis calcium binding protein, putative 0.014 0.041 0.1068
Echinococcus granulosus proteasome subunit alpha type 6 0.0034 0.0057 0.0054
Leishmania major centrin, putative 0.014 0.041 0.071
Schistosoma mansoni cercarial elastase (S01 family) 0.0141 0.0413 0.041
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0257 0.0803 0.2103
Toxoplasma gondii peptidase family M13 protein 0.0096 0.0265 0.0457
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0282 0.0886 0.232
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.014 0.041 0.071
Brugia malayi Papain family cysteine protease containing protein 0.0282 0.0886 0.0882
Trypanosoma cruzi kinesin, putative 0.0618 0.2008 0.2005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.026 0.0256
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0057 0.0141
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0172 0.0168
Plasmodium vivax plasmepsin IV, putative 0.0042 0.0082 0.0206
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0034 0.0057 0.011
Loa Loa (eye worm) hypothetical protein 0.1156 0.3805 0.3803
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0018 0.0014
Schistosoma mansoni cathepsin D (A01 family) 0.0228 0.0707 0.0703
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0099
Loa Loa (eye worm) cathepsin B 0.1126 0.3705 0.3702
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0208 0.0637 0.1108
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2474 0.8209 0.8208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0886 0.232
Brugia malayi ecdysteroid receptor 0.0022 0.0018 0.0014
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.026 0.0256
Mycobacterium tuberculosis Long conserved protein 0.0284 0.0891 0.1677
Entamoeba histolytica hypothetical protein, conserved 0.0142 0.0418 0.1062
Brugia malayi MH2 domain containing protein 0.0123 0.0354 0.035
Leishmania major proteasome alpha 1 subunit, putative 0.0034 0.0057 0.0094
Brugia malayi Cathepsin L-like precursor 0.1156 0.3805 0.3803
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0188 0.0572 0.0568
Loa Loa (eye worm) hypothetical protein 0.0073 0.0187 0.0183
Loa Loa (eye worm) hypothetical protein 0.0096 0.0265 0.0261
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0141 0.0413 0.041
Mycobacterium ulcerans proteasome PrcB 0.0174 0.0525 0.2083
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.006 0.0097
Loa Loa (eye worm) hypothetical protein 0.0073 0.0187 0.0183
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0084 0.0223 0.0219
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0034 0.0057 0.0094
Echinococcus granulosus prolyl endopeptidase 0.1729 0.5721 0.5719
Trichomonas vaginalis calcium binding protein, putative 0.014 0.041 0.1068
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0018 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0018 0.0014
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0665 0.2164 0.2161

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.1582 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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