Detailed information for compound 1392391

Basic information

Technical information
  • TDR Targets ID: 1392391
  • Name: dimethyl 1-[(4-methoxyphenyl)methyl]-4-thioph en-3-yl-4H-pyridine-3,5-dicarboxylate
  • MW: 399.46 | Formula: C21H21NO5S
  • H donors: 0 H acceptors: 2 LogP: 3.09 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C1=CN(Cc2ccc(cc2)OC)C=C(C1c1cscc1)C(=O)OC
  • InChi: 1S/C21H21NO5S/c1-25-16-6-4-14(5-7-16)10-22-11-17(20(23)26-2)19(15-8-9-28-13-15)18(12-22)21(24)27-3/h4-9,11-13,19H,10H2,1-3H3
  • InChiKey: SMNKTCOQJWBYKJ-UHFFFAOYSA-N  


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Synonyms

  • dimethyl 1-[(4-methoxyphenyl)methyl]-4-(3-thienyl)-4H-pyridine-3,5-dicarboxylate
  • 1-[(4-methoxyphenyl)methyl]-4-(3-thienyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl ester
  • 1-(4-methoxybenzyl)-4-(3-thienyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl ester
  • ST5274954
  • MLS000692899
  • SMR000285591
  • ZINC00781160
  • BIM-0022384.P001
  • 1-(4-Methoxy-benzyl)-4-thiophen-3-yl-1,4-dihydro-pyridine-3,5-dicarboxylic acid
  • BAS 04378060
  • CBMicro_022264

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii proteasome subunit alpha type, putative 0.0025 0.0003 0.0006
Echinococcus granulosus caspase 2 0.0064 0.0033 0.0031
Plasmodium falciparum cysteine repeat modular protein 1 0.0035 0.0011 0.0069
Brugia malayi cathepsin F-like cysteine proteinase 0.0522 0.0374 0.0372
Echinococcus multilocularis cysteine protease 0.1972 0.1455 0.1453
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0686 0.0496 0.1435
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1678 0.1235 0.1234
Onchocerca volvulus 0.0035 0.0011 0.0018
Brugia malayi Cathepsin L-like precursor 0.1972 0.1455 0.1454
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0025 0.0003 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.1207 0.0885 0.3931
Plasmodium vivax proteasome subunit beta type-5, putative 0.0177 0.0117 0.0365
Echinococcus granulosus proteasome subunit beta t family 0.0025 0.0003 0.0002
Echinococcus granulosus EF hand domain containing family member A2 0.0674 0.0487 0.0486
Leishmania major cathepsin L-like protease 0.22 0.1624 0.4726
Loa Loa (eye worm) calpain 0.4272 0.3168 0.3168
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.124 0.0909 0.2644
Loa Loa (eye worm) hypothetical protein 0.0036 0.0011 0.0011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.124 0.0909 0.0908
Toxoplasma gondii calmodulin CAM1 0.0674 0.0487 0.1416
Trypanosoma cruzi kinesin, putative 0.3032 0.2244 0.2243
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Schistosoma mansoni neuronal calcium sensor 0.0666 0.0481 0.048
Schistosoma mansoni regulator of G protein signaling 0.0036 0.0011 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.3167
Echinococcus granulosus proteasome prosome macropain 0.0177 0.0117 0.0115
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0064 0.0033 0.0091
Plasmodium vivax vivapain-1 0.1207 0.0885 0.279
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.4272 0.3168 0.3167
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0031 0.0086
Trypanosoma cruzi centrin, putative 0.0746 0.0541 0.0539
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Loa Loa (eye worm) hypothetical protein 0.0043 0.0017 0.0017
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.006 0.003 0.0118
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.124 0.0909 0.264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0686 0.0496 0.1436
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 1.344 1 1
Trypanosoma brucei calpain-like protein, putative 0.4272 0.3168 0.9223
Schistosoma mansoni chromobox protein 0.0061 0.003 0.0029
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0169 0.0111 0.0111
Echinococcus multilocularis calpain family protein 1, d 0.8397 0.6242 0.6242
Loa Loa (eye worm) hypothetical protein 0.0686 0.0496 0.0496
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0025 0.0003 0.0006
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.006 0.003 0.0028
Onchocerca volvulus Cell death protein 3 homolog 0.0064 0.0033 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0011 0.0025
Schistosoma mansoni centrin-related 0.0666 0.0481 0.048
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0686 0.0496 0.1563
Toxoplasma gondii cathepsin CPC1 0.0686 0.0496 0.144
Schistosoma mansoni caspase-7 (C14 family) 0.0135 0.0086 0.0084
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Entamoeba histolytica cysteine proteinase, putative 0.1207 0.0885 0.3931
Echinococcus granulosus cysteine protease 0.1207 0.0885 0.0883
Echinococcus granulosus Proteasome subunit alpha beta 0.0025 0.0003 0.0002
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.124 0.0909 0.0908
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0666 0.0481 0.1394
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0686 0.0496 0.1436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Trichomonas vaginalis chromobox protein, putative 0.0037 0.0012 0.0027
Toxoplasma gondii preprocathepsin c precursor, putative 0.0686 0.0496 0.144
Entamoeba histolytica hypothetical protein 0.0036 0.0011 0.0036
Onchocerca volvulus 0.0073 0.0039 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0031 0.0081
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0064 0.0032 0.0129
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0011 0.0011
Echinococcus multilocularis microtubule associated protein 2 0.0737 0.0534 0.0533
Loa Loa (eye worm) fibroinase 0.1972 0.1455 0.1455
Brugia malayi calpain 5 0.3032 0.2244 0.2243
Trichomonas vaginalis calmodulin, putative 0.0666 0.0481 0.1394
Plasmodium vivax proteasome subunit beta type-1, putative 0.0064 0.0032 0.0099
Onchocerca volvulus 0.0035 0.0011 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0011 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0033 0.0087
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.4272 0.3168 0.3167
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0025 0.0003 0.0006
Entamoeba histolytica hypothetical protein 0.0036 0.0011 0.0036
Trichomonas vaginalis centrin, putative 0.0666 0.0481 0.1394
Loa Loa (eye worm) ctsf protein 0.1972 0.1455 0.1455
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0011 0.0025
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0025 0.0003 0.0002
Loa Loa (eye worm) EF hand family protein 0.0666 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1972 0.1455 0.1455
Brugia malayi Proteasome subunit alpha type 7-1 0.0025 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Brugia malayi Regulator of G protein signaling domain containing protein 0.0036 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0686 0.0496 0.0496
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0025 0.0003 0.0006
Brugia malayi chromobox protein homolog 3 0.0034 0.001 0.0009
Brugia malayi hypothetical protein 0.0036 0.0011 0.001
Mycobacterium ulcerans proteasome PrcB 0.0177 0.0117 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0014 0.0014
Entamoeba histolytica cysteine protease, putative 0.0686 0.0496 0.2197
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0686 0.0496 0.1436
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Trypanosoma brucei Calpain-like protein CALP1.3 0.124 0.0909 0.2644
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.001
Toxoplasma gondii proteasome subunit beta type 2, putative 0.006 0.003 0.0083
Brugia malayi programmed cell death protein 6 0.0666 0.0481 0.048
Plasmodium falciparum serine repeat antigen 7 0.0686 0.0496 0.3405
Toxoplasma gondii microneme protein MIC17C 0.0035 0.0011 0.0028
Leishmania major metacaspase, putative 0.0164 0.0107 0.0308
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0025 0.0003 0.0002
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.008 0.0044 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0012 0.001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Echinococcus granulosus calcyphosin protein 0.008 0.0044 0.0043
Schistosoma mansoni calpain-7 (C02 family) 0.4272 0.3168 0.3167
Brugia malayi Papain family cysteine protease containing protein 0.0686 0.0496 0.0495
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0025 0.0003 0.0006
Plasmodium falciparum cysteine proteinase falcipain 3 0.1972 0.1455 1
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0019 0.0018
Echinococcus multilocularis proteasome subunit alpha type 6 0.0025 0.0003 0.0002
Echinococcus granulosus proteasome subunit alpha type 2 0.0025 0.0003 0.0002
Giardia lamblia Hypothetical protein 0.0686 0.0496 0.1435
Plasmodium vivax SET domain protein, putative 0.0024 0.0003 0.0007
Trichomonas vaginalis calcium binding protein, putative 0.0746 0.0541 0.1566
Trypanosoma brucei metacaspase MCA3 0.0164 0.0107 0.0308
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 1.344 1 1
Trypanosoma cruzi metacaspase 5, putative 0.0164 0.0107 0.0106
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0025 0.0003 0.0008
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0025 0.0003 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Giardia lamblia Proteasome subunit beta type 2 0.006 0.003 0.0077
Schistosoma mansoni axis inhibition protein axin 0.0036 0.0011 0.001
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0177 0.0117 0.0115
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Brugia malayi Calmodulin-like protein 0.0666 0.0481 0.048
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.124 0.0909 0.0908
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0007 0.0006
Giardia lamblia Cathepsin L precursor 0.0686 0.0496 0.1435
Echinococcus multilocularis programmed cell death protein 0.0746 0.0541 0.0539
Plasmodium falciparum serine repeat antigen 9 0.0686 0.0496 0.3405
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0025 0.0003 0.0006
Schistosoma mansoni cathepsin B (C01 family) 0.0686 0.0496 0.0495
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0686 0.0496 0.1563
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Plasmodium vivax unspecified product 0.1207 0.0885 0.279
Leishmania major proteasome beta 7 subunit, putative 0.0025 0.0003 0.0006
Entamoeba histolytica cysteine protease, putative 0.0686 0.0496 0.2197
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.124 0.0909 0.264
Echinococcus multilocularis Tolloid protein 1 0.0033 0.0009 0.0008
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0064 0.0032 0.0091
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0025 0.0003 0.0003
Brugia malayi fibroinase precursor 0.0686 0.0496 0.0495
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0686 0.0496 0.0495
Brugia malayi cathepsin L-like precursor 0.1451 0.1066 0.1065
Giardia lamblia Cathepsin L precursor 0.0686 0.0496 0.1435
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0025 0.0003 0.0008
Entamoeba histolytica calpain family cysteine protease, putative 0.124 0.0909 0.4041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0686 0.0496 0.1436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Trichomonas vaginalis calmodulin, putative 0.0746 0.0541 0.1566
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0025 0.0003 0.0002
Trypanosoma brucei Component of motile flagella 41 0.0666 0.0481 0.1398
Schistosoma mansoni hypothetical protein 0.0666 0.0481 0.048
Schistosoma mansoni microtubule-associated protein tau 0.0737 0.0534 0.0533
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0006 0.0466
Brugia malayi Cathepsin L-like precursor 0.1972 0.1455 0.1454
Giardia lamblia Cysteine protease 0.0686 0.0496 0.1435
Onchocerca volvulus 0.0666 0.0481 0.0902
Trypanosoma brucei Aph-1 protein, putative 0.0046 0.0019 0.0051
Trichomonas vaginalis calpain, putative 0.124 0.0909 0.264
Echinococcus multilocularis calumenin 0.0674 0.0487 0.0486
Schistosoma mansoni regulator of G protein signaling 0.0036 0.0011 0.001
Echinococcus multilocularis cysteine protease 0.1972 0.1455 0.1453
Brugia malayi proteasome subunit beta type 2 0.006 0.003 0.0029
Echinococcus multilocularis tumor protein p63 0.0267 0.0184 0.0183
Schistosoma mansoni hypothetical protein 0.0666 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Entamoeba histolytica cysteine protease, putative 0.0686 0.0496 0.2197
Entamoeba histolytica cysteine proteinase, putative 0.1207 0.0885 0.3931
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0025 0.0003 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0031 0.0086
Onchocerca volvulus 0.0035 0.0011 0.0018
Echinococcus granulosus neurocalcin 0.0666 0.0481 0.048
Entamoeba histolytica hypothetical protein 0.0036 0.0011 0.0036
Schistosoma mansoni chromobox protein 0.0061 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.008 0.0044 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.1207 0.0885 0.0883
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1207 0.0885 0.0883
Trichomonas vaginalis calmodulin, putative 0.0666 0.0481 0.1394
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0025 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0177 0.0117 0.0505
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.006 0.003 0.0079
Loa Loa (eye worm) hypothetical protein 0.0686 0.0496 0.0496
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0031 0.003
Trichomonas vaginalis kakapo, putative 0.008 0.0044 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0686 0.0496 0.1436
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Brugia malayi EF hand family protein 0.0674 0.0487 0.0486
Echinococcus multilocularis Calcium binding protein 0.008 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Trypanosoma brucei proteasome beta 6 subunit 0.0064 0.0032 0.0091
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0666 0.0481 0.048
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0025 0.0003 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0031 0.003
Echinococcus multilocularis cathepsin L cysteine protease 0.1972 0.1455 0.1453
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0025 0.0003 0.0002
Entamoeba histolytica calpain large subunit domain III containing protein 0.3032 0.2244 0.9998
Trypanosoma brucei protein kinase, putative 0.0062 0.0031 0.0086
Loa Loa (eye worm) calpain family protein 1 1.1429 0.8502 0.8502
Schistosoma mansoni cathepsin F (C01 family) 0.1972 0.1455 0.1453
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0033 0.0087
Leishmania major cysteine peptidase A (CPA) 0.1972 0.1455 0.4232
Toxoplasma gondii hypothetical protein 0.0035 0.0011 0.0028
Trypanosoma cruzi caltractin, putative 0.0666 0.0481 0.048
Trichomonas vaginalis calmodulin-2, putative 0.0666 0.0481 0.1394
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0686 0.0496 0.0495
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0177 0.0117 0.0117
Plasmodium falciparum centrin-4 0.008 0.0044 0.0299
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0025 0.0003 0.0006
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0007 0.0007
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Echinococcus granulosus caspase 0.0135 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Echinococcus granulosus calpain 5 0.4272 0.3168 0.3167
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1972 0.1455 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Trichomonas vaginalis calmodulin, putative 0.0666 0.0481 0.1394
Trypanosoma brucei calpain, putative 0.124 0.0909 0.2644
Brugia malayi hypothetical protein 0.0358 0.0252 0.0251
Echinococcus granulosus caspase 8 0.0064 0.0033 0.0031
Echinococcus multilocularis neurocalcin 0.0666 0.0481 0.048
Loa Loa (eye worm) calmodulin-like protein 0.0666 0.0481 0.0481
Plasmodium vivax metacaspase 1, putative 0.0164 0.0107 0.0336
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0049 0.0022 0.006
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Echinococcus granulosus chromobox protein 1 0.0061 0.003 0.0029
Echinococcus multilocularis caspase 0.0135 0.0086 0.0084
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0025 0.0003 0.0002
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0686 0.0496 0.1436
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0036 0.0011 0.001
Entamoeba histolytica cysteine proteinase 1, putative 0.1207 0.0885 0.3931
Loa Loa (eye worm) proteasome subunit beta type 2 0.006 0.003 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.22 0.1624 0.1623
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0686 0.0496 0.0495
Leishmania major phospholipase c-like protein 0.0666 0.0481 0.1398
Echinococcus granulosus cathepsin b 1.344 1 1
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0025 0.0003 0.0002
Leishmania major cathepsin L-like protease 0.1972 0.1455 0.4232
Trypanosoma brucei Metacaspase-4 0.0064 0.0033 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0024 0.0003 0.0002
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0025 0.0003 0.0002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.9223
Trypanosoma cruzi I/6 autoantigen, putative 0.0666 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Loa Loa (eye worm) proteasome subunit beta type 3 0.0025 0.0003 0.0003
Echinococcus multilocularis Regulator of G protein signaling 20 0.0036 0.0011 0.001
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0031 0.0086
Echinococcus granulosus calpain A 0.4272 0.3168 0.3167
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.124 0.0909 0.0908
Leishmania major proteasome alpha 1 subunit, putative 0.0025 0.0003 0.0006
Toxoplasma gondii centrin 0.0666 0.0481 0.1398
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0025 0.0003 0.0008
Brugia malayi Proteasome A-type and B-type family protein 0.0177 0.0117 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1207 0.0885 0.2569
Loa Loa (eye worm) hypothetical protein 1.0189 0.7577 0.7577
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0025 0.0003 0.0006
Brugia malayi hypothetical protein 0.0036 0.0011 0.001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.463 0.3435 0.3434
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0025 0.0003 0.0018
Echinococcus multilocularis centrin 2 0.0666 0.0481 0.048
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0025 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0033 0.0087
Toxoplasma gondii PAN domain-containing protein 0.0217 0.0146 0.0423
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.001 0.0009
Plasmodium falciparum metacaspase-like protein 0.0064 0.0033 0.0219
Echinococcus multilocularis axis inhibition protein axin 0.0036 0.0011 0.001
Entamoeba histolytica protein kinase, putative 0.3032 0.2245 1
Entamoeba histolytica grainin 2 0.008 0.0044 0.0182
Loa Loa (eye worm) hypothetical protein 0.0031 0.0008 0.0008
Plasmodium falciparum serine repeat antigen 6 0.0686 0.0496 0.3405
Echinococcus granulosus family C2 unassigned peptidase C02 family 1.2095 0.8998 0.8998
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0686 0.0496 0.1436
Echinococcus granulosus calmodulin 0.0666 0.0481 0.048
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0666 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0025 0.0003 0.0002
Brugia malayi Pre-SET motif family protein 0.0024 0.0003 0.0002
Leishmania major proteasome beta 3 subunit, putative 0.0025 0.0003 0.0006
Plasmodium vivax vivapain-2 0.1972 0.1455 0.459
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0006 0.0015
Loa Loa (eye worm) calpain D 0.124 0.0909 0.0909
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0686 0.0496 0.1563
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0686 0.0496 0.1436
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0031 0.0086
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0031 0.0029
Brugia malayi proteasome subunit beta type 1 0.0064 0.0032 0.0031
Schistosoma mansoni neuronal calcium sensor 0.0666 0.0481 0.048
Onchocerca volvulus 0.0035 0.0011 0.0018
Schistosoma mansoni regulator of G protein signaling 0.0036 0.0011 0.001
Trypanosoma brucei proteasome subunit beta type-2, putative 0.006 0.003 0.0083
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0686 0.0496 0.3405
Toxoplasma gondii heat shock protein hslv, putative 0.0025 0.0003 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.1451 0.1066 0.1065
Onchocerca volvulus 0.0686 0.0496 0.093
Loa Loa (eye worm) programmed cell death protein 6 0.0674 0.0487 0.0487
Brugia malayi Protein kinase domain containing protein 0.0035 0.0011 0.001
Schistosoma mansoni axis inhibition protein axin 0.0036 0.0011 0.001
Schistosoma mansoni centrin 0.0666 0.0481 0.048
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0073 0.0039 0.0038
Echinococcus granulosus calpain 0.4272 0.3168 0.3167
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0025 0.0003 0.0006
Toxoplasma gondii proteasome subunit 0.0025 0.0003 0.0006
Giardia lamblia Cathepsin L precursor 0.0686 0.0496 0.1435
Leishmania major cathepsin L-like protease 0.22 0.1624 0.4726
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.463 0.3435 1
Onchocerca volvulus 0.0035 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Echinococcus multilocularis proteasome subunit beta type 7 0.0025 0.0003 0.0002
Trypanosoma cruzi metacaspase, putative 0.0164 0.0107 0.0106
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0023 0.0002 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Brugia malayi hypothetical protein 0.0119 0.0074 0.0073
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0686 0.0496 0.0495
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0177 0.0117 0.0336
Trypanosoma cruzi calmodulin, putative 0.0666 0.0481 0.048
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.0007 0.0517
Trypanosoma cruzi 20S proteasome subunit 0.006 0.003 0.0029
Plasmodium falciparum proteasome subunit beta type-5 0.0177 0.0117 0.0796
Onchocerca volvulus Cathepsin L homolog 0.1972 0.1455 0.2733
Plasmodium vivax proteasome subunit beta type-6, putative 0.0025 0.0003 0.0008
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Toxoplasma gondii subtilisin SUB12 0.0035 0.0011 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Entamoeba histolytica cysteine protease, putative 0.0686 0.0496 0.2197
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0686 0.0496 0.1436
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0666 0.0481 0.048
Leishmania major proteasome alpha 2 subunit, putative 0.0025 0.0003 0.0006
Echinococcus multilocularis hypothetical protein 0.4272 0.3168 0.3167
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0006 0.0012
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0064 0.0033 0.0031
Schistosoma mansoni ef hand domain family member A2 0.0666 0.0481 0.048
Trichomonas vaginalis centrin, putative 0.0666 0.0481 0.1394
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0714 0.0517 0.0516
Loa Loa (eye worm) hypothetical protein 0.0522 0.0374 0.0374
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0006 0.0466
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Onchocerca volvulus 0.0035 0.0011 0.0018
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0117 0.0072 0.0072
Trypanosoma brucei Calpain-like protein 1.1 0.124 0.0909 0.2644
Entamoeba histolytica cysteine proteinase, putative 0.1451 0.1066 0.4741
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0049 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0119 0.0074 0.0074
Trichomonas vaginalis chromobox protein, putative 0.0061 0.003 0.0079
Loa Loa (eye worm) myosin regulatory light chain 1 0.008 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0686 0.0496 0.0496
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0006 0.0005
Giardia lamblia Cathepsin B precursor 0.0686 0.0496 0.1435
Trichomonas vaginalis calcineurin B subunit, putative 0.0666 0.0481 0.1394
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0686 0.0496 0.1436
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0006 0.0012
Echinococcus multilocularis geminin 0.0147 0.0095 0.0093
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0666 0.0481 0.048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0022 0.1803
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.124 0.0909 0.264
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Trichomonas vaginalis calmodulin, putative 0.0666 0.0481 0.1394
Brugia malayi Kringle domain containing protein 0.0035 0.0011 0.001
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0686 0.0496 0.1563
Brugia malayi cathepsin Z-like cysteine proteinase 0.0686 0.0496 0.0495
Echinococcus granulosus cathepsin l cysteine peptidase 0.1972 0.1455 0.1453
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0025 0.0003 0.0002
Echinococcus granulosus regulator of G protein signaling 7 0.0036 0.0011 0.001
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Onchocerca volvulus Cathepsin L homolog 0.1972 0.1455 0.2733
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Trichomonas vaginalis calmodulin, putative 0.0674 0.0487 0.1412
Schistosoma mansoni SmCB2 peptidase (C01 family) 1.344 1 1
Toxoplasma gondii calmodulin CAM2 0.008 0.0044 0.0125
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0035 0.0011 0.0031
Echinococcus granulosus cathepsin L cysteine protease 0.1207 0.0885 0.0883
Entamoeba histolytica calmodulin, putative 0.0666 0.0481 0.2132
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0025 0.0003 0.0002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.4272 0.3168 0.3167
Plasmodium falciparum serine repeat antigen 2 0.0686 0.0496 0.3405
Toxoplasma gondii PAN domain-containing protein 0.0217 0.0146 0.0423
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0025 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.1451 0.1066 0.1066
Schistosoma mansoni calpain (C02 family) 0.4272 0.3168 0.3167
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0006 0.0466
Schistosoma mansoni calpain-7 (C02 family) 0.4272 0.3168 0.3167
Schistosoma mansoni calmodulin-related 0.008 0.0044 0.0043
Onchocerca volvulus 0.1972 0.1455 0.2733
Echinococcus granulosus histone lysine methyltransferase setb 0.0024 0.0003 0.0002
Toxoplasma gondii centrin, putative 0.0666 0.0481 0.1398
Plasmodium vivax serine-repeat antigen (SERA) 0.0686 0.0496 0.1563
Trypanosoma brucei protein I/6 0.0666 0.0481 0.1398
Echinococcus granulosus Proteasome subunit alpha type 7 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.1451 0.1066 0.1066
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.124 0.0909 0.2644
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Echinococcus multilocularis caspase 3 0.0071 0.0038 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Brugia malayi calpain family protein 1 1.1429 0.8502 0.8501
Echinococcus multilocularis proteasome subunit alpha type 2 0.0025 0.0003 0.0002
Giardia lamblia Programmed cell death protein-like protein 0.008 0.0044 0.0119
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Leishmania major proteasome alpha 3 subunit, putative 0.0025 0.0003 0.0006
Brugia malayi Cell death protein 3 precursor 0.0064 0.0033 0.0031
Entamoeba histolytica cysteine protease, putative 0.0686 0.0496 0.2197
Leishmania major cytochrome p450-like protein 0.0029 0.0007 0.0016
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0025 0.0003 0.0002
Giardia lamblia Cathepsin B precursor 0.0686 0.0496 0.1435
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0666 0.0481 0.2132
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0031 0.0081
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0025 0.0003 0.0006
Onchocerca volvulus 0.1972 0.1455 0.2733
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0025 0.0003 0.0002
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0025 0.0003 0.0018
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0025 0.0003 0.0002
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0011 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Brugia malayi Proteasome subunit alpha type 1 0.0025 0.0003 0.0002
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0135 0.0086 0.0084
Brugia malayi proteasome subunit alpha type 3 0.0025 0.0003 0.0002
Leishmania major calmodulin-like protein 0.0666 0.0481 0.1398
Entamoeba histolytica cysteine protease, putative 0.1972 0.1455 0.6475
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.4272 0.3168 0.9223
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0064 0.0033 0.0031
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0686 0.0496 0.1435
Onchocerca volvulus 0.1972 0.1455 0.2733
Loa Loa (eye worm) heterochromatin protein 1 0.0061 0.003 0.003
Echinococcus multilocularis proteasome subunit beta type 6 0.0025 0.0003 0.0002
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0064 0.0032 0.0217
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0031 0.0081
Schistosoma mansoni neuronal calcium sensor 0.0666 0.0481 0.048
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0025 0.0003 0.0006
Toxoplasma gondii kringle domain-containing protein 0.0035 0.0011 0.0028
Onchocerca volvulus 0.0035 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0666 0.0481 0.0481
Onchocerca volvulus 0.0029 0.0006 0.0009
Echinococcus multilocularis calbindin 32 0.0674 0.0487 0.0486
Brugia malayi Cytochrome P450 family protein 0.0029 0.0007 0.0006
Brugia malayi MAP kinase sur-1 0.0062 0.0031 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.3167
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Mycobacterium ulcerans hypothetical protein 0.0029 0.0006 0.0466
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0049 0.0022 0.002
Onchocerca volvulus 0.0034 0.001 0.0017
Giardia lamblia Cathepsin L precursor 0.0686 0.0496 0.1435
Loa Loa (eye worm) hypothetical protein 0.1972 0.1455 0.1455
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Leishmania major i/6 autoantigen-like protein 0.0666 0.0481 0.1398
Echinococcus multilocularis calcyphosin protein 0.008 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Plasmodium vivax centrin-1, putative 0.0666 0.0481 0.1516
Echinococcus granulosus cathepsin l1 0.1972 0.1455 0.1453
Echinococcus multilocularis cathepsin b 1.344 1 1
Echinococcus granulosus regulator of G protein signaling 3 0.0036 0.0011 0.001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0686 0.0496 0.0496
Trypanosoma cruzi calpain cysteine peptidase, putative 0.4272 0.3168 0.3167
Trypanosoma brucei cysteine peptidase C (CPC) 0.463 0.3435 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0025 0.0003 0.0002
Schistosoma mansoni regulator of G protein signaling 0.0036 0.0011 0.001
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0025 0.0003 0.0008
Echinococcus granulosus beta-adrenergic receptor kinase 0.0036 0.0012 0.001
Brugia malayi Proteasome A-type and B-type family protein 0.0025 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0686 0.0496 0.1436
Loa Loa (eye worm) hypothetical protein 0.0666 0.0481 0.0481
Brugia malayi PXA domain containing protein 0.0036 0.0011 0.001
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0686 0.0496 0.1563
Giardia lamblia Cathepsin B precursor 0.463 0.3435 1
Brugia malayi latrophilin 2 splice variant baaae 0.003 0.0007 0.0006
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0011 0.0011
Trypanosoma brucei centrin, putative 0.0666 0.0481 0.1398
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0001 0.5
Trichomonas vaginalis caltractin, putative 0.008 0.0044 0.0121
Entamoeba histolytica grainin 2 0.0746 0.0541 0.2396
Brugia malayi Pre-SET motif family protein 0.0169 0.0111 0.011
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0017 0.0016
Trichomonas vaginalis calcium binding proteins, putative 0.0666 0.0481 0.1394
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Trichomonas vaginalis calmodulin, putative 0.008 0.0044 0.0121
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0007 0.0006
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0011 0.0011
Plasmodium falciparum proteasome subunit beta type-2, putative 0.006 0.003 0.0199
Echinococcus granulosus cathepsin l1 0.1451 0.1066 0.1065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0036 0.0011 0.001
Leishmania major centrin, putative 0.0666 0.0481 0.1398
Leishmania major cathepsin L-like protease 0.1972 0.1455 0.4232
Leishmania major calpain family cysteine protease-like protein 0.124 0.0909 0.2644
Echinococcus multilocularis calpain A 1.2103 0.9004 0.9004
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0036 0.0011 0.0025
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0011 0.0011
Onchocerca volvulus 0.0119 0.0074 0.0136
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.008 0.0044 0.0137
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0006 0.0537
Loa Loa (eye worm) hypothetical protein 0.0686 0.0496 0.0496
Schistosoma mansoni caspase-7 (C14 family) 0.0064 0.0033 0.0031
Trypanosoma brucei metacaspase MCA2 0.0164 0.0107 0.0308
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0177 0.0117 1
Onchocerca volvulus 0.1972 0.1455 0.2733
Trypanosoma cruzi cruzipain precursor, putative 0.0522 0.0374 0.0372
Toxoplasma gondii proteasome subunit alpha1, putative 0.0025 0.0003 0.0006
Schistosoma mansoni myosin regulatory light chain 0.008 0.0044 0.0043
Onchocerca volvulus 0.008 0.0044 0.0081
Loa Loa (eye worm) CYP4Cod1 0.0029 0.0007 0.0007
Onchocerca volvulus 0.0035 0.0011 0.0018
Giardia lamblia Cathepsin B precursor 0.463 0.3435 1
Echinococcus granulosus Tolloid protein 1 0.0033 0.0009 0.0008
Plasmodium vivax calpain, putative 0.4272 0.3168 1
Trichomonas vaginalis set domain proteins, putative 0.0193 0.0129 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0177 0.0117 0.033
Schistosoma mansoni myosin light chain 0.008 0.0044 0.0043
Echinococcus granulosus caspase 3 0.0071 0.0038 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0686 0.0496 0.1436
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0177 0.0117 1
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0025 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Giardia lamblia Cysteine protease 0.0686 0.0496 0.1435
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0025 0.0003 0.0002
Echinococcus multilocularis cathepsin b 1.344 1 1
Schistosoma mansoni z-protein (S1r protein) 0.0036 0.0011 0.001
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.463 0.3435 0.3434
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0025 0.0003 0.0006
Trypanosoma cruzi I/6 autoantigen, putative 0.0666 0.0481 0.048
Trypanosoma brucei proteasome beta 7 subunit 0.0025 0.0003 0.0006
Loa Loa (eye worm) trypsin family protein 0.0022 0.0001 0.0001
Entamoeba histolytica calcium binding family protein 0.0666 0.0481 0.2132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0686 0.0496 0.1563
Trypanosoma brucei Calpain-like protein 1.2 0.124 0.0909 0.2644
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0686 0.0496 0.1563
Echinococcus granulosus calpain A 1.2103 0.9004 0.9004
Brugia malayi EF hand family protein 0.0666 0.0481 0.048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.3167
Brugia malayi Papain family cysteine protease containing protein 0.0686 0.0496 0.0495
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.463 0.3435 1
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0011 0.0028
Schistosoma mansoni hypothetical protein 0.0073 0.0039 0.0038
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1972 0.1455 0.1453
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0024 0.0003 0.0002
Onchocerca volvulus 0.0027 0.0005 0.0006
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0025 0.0003 0.0018
Leishmania major hypothetical protein, conserved 0.0666 0.0481 0.1398
Echinococcus granulosus cathepsin L 0.0686 0.0496 0.0495
Leishmania major proteasome beta 2 subunit, putative 0.006 0.003 0.0083
Giardia lamblia Hypothetical protein 0.0674 0.0487 0.141
Echinococcus granulosus tumor protein p63 0.0267 0.0184 0.0183
Onchocerca volvulus Notchless protein homolog 0.0025 0.0003 0.0004
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0025 0.0003 0.0006
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0031 0.0031
Toxoplasma gondii microneme protein MIC17B 0.0035 0.0011 0.0028
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0017 0.0016
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Schistosoma mansoni calpain-2 (C02 family) 0.124 0.0909 0.0908
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0033 0.0087
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0025 0.0003 0.0006
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0031 0.0029
Plasmodium falciparum metacaspase 1 0.0164 0.0107 0.0731
Echinococcus granulosus regulator of G protein signaling 3 0.0036 0.0011 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0011 0.0025
Plasmodium vivax unspecified product 0.0686 0.0496 0.1563
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0522 0.0374 0.0372
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0037 0.0012 0.002
Trypanosoma brucei hypothetical protein 0.124 0.0909 0.2644
Trypanosoma brucei calpain, putative 0.124 0.0909 0.2644
Loa Loa (eye worm) hypothetical protein 0.1451 0.1066 0.1066
Trichomonas vaginalis calcium binding protein, putative 0.0666 0.0481 0.1394
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0006 0.0012
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Brugia malayi Myosin regulatory light chain 1 0.008 0.0044 0.0043
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0164 0.0107 0.0308
Brugia malayi gamma-secretase subunit aph-1 0.0117 0.0072 0.0071
Mycobacterium ulcerans hypothetical protein 0.0022 0.0001 0.0045
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0006 0.0466
Echinococcus granulosus neuronal calcium sensor 0.0666 0.0481 0.048
Giardia lamblia Calmodulin 0.008 0.0044 0.0119
Giardia lamblia Cathepsin L-like protease 0.0686 0.0496 0.1435
Trypanosoma cruzi centrin, putative 0.0746 0.0541 0.0539
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Echinococcus multilocularis regulator of G protein signaling 7 0.0036 0.0011 0.001
Onchocerca volvulus Cathepsin F homolog 0.1972 0.1455 0.2733
Onchocerca volvulus 0.0035 0.0011 0.0018
Echinococcus granulosus Calcium binding protein 0.008 0.0044 0.0043
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0036 0.0011 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0024 0.0003 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0001 0.0003
Echinococcus multilocularis proteasome (prosome, macropain) 0.0177 0.0117 0.0115
Onchocerca volvulus 0.0035 0.0011 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0022 0.002
Trichomonas vaginalis chromobox protein, putative 0.0061 0.003 0.0079
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0025 0.0003 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0022 0.1803
Brugia malayi Cathepsin L-like precursor 0.0522 0.0374 0.0372
Brugia malayi proteasome subunit alpha type 2 0.0025 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0007 0.0007
Trypanosoma brucei calmodulin, putative 0.0674 0.0487 0.1416
Loa Loa (eye worm) hypothetical protein 0.0036 0.0011 0.0011
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0025 0.0003 0.0008
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.006 0.003 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0033 0.0087
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0025 0.0003 0.0002
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 1.1429 0.8502 0.8501
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.001 0.0022
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0025 0.0003 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0012 0.001
Brugia malayi Proteasome A-type and B-type family protein 0.0025 0.0003 0.0002
Leishmania major proteasome alpha 1 subunit, putative 0.0025 0.0003 0.0006
Echinococcus granulosus programmed cell death protein 0.0746 0.0541 0.0539
Onchocerca volvulus 0.1972 0.1455 0.2733
Leishmania major centrin, putative 0.0666 0.0481 0.1398
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0025 0.0003 0.0018
Echinococcus multilocularis tissue type plasminogen activator 0.0035 0.0011 0.0009
Plasmodium vivax unspecified product 0.0522 0.0374 0.1177
Echinococcus granulosus EF hand domain containing family member A2 0.0666 0.0481 0.048
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0011 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0092 0.0092
Echinococcus granulosus Regulator of G protein signaling 20 0.0036 0.0011 0.001
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0036 0.0011 0.001
Echinococcus granulosus chromobox protein 1 0.0061 0.003 0.0029
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Toxoplasma gondii calcium binding protein precursor, putative 0.008 0.0044 0.0125
Brugia malayi Papain family cysteine protease containing protein 0.1207 0.0885 0.0883
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0024 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0358 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1451 0.1066 0.3097
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0025 0.0003 0.0002
Brugia malayi MH2 domain containing protein 0.0144 0.0092 0.0091
Onchocerca volvulus 0.0035 0.0011 0.0018
Loa Loa (eye worm) calpain family protein 1 0.8397 0.6242 0.6242
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.9223
Brugia malayi cathepsin L-like cysteine proteinase 0.0686 0.0496 0.0495
Loa Loa (eye worm) calpain 5 0.3032 0.2244 0.2244
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0044 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0036 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1207 0.0885 0.2569
Plasmodium vivax proteasome subunit beta type-4, putative 0.0025 0.0003 0.0008
Trypanosoma brucei centrin-3 0.0746 0.0541 0.157
Mycobacterium ulcerans proteasome PrcA 0.0025 0.0003 0.0225
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.124 0.0909 0.0908
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1207 0.0885 0.2572
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0025 0.0003 0.0003
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0025 0.0004 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Trypanosoma brucei hypothetical protein, conserved 0.0666 0.0481 0.1398
Plasmodium falciparum serine repeat antigen 4 0.0686 0.0496 0.3405
Echinococcus granulosus calbindin 32 0.0674 0.0487 0.0486
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0025 0.0003 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0666 0.0481 0.1394
Entamoeba histolytica cysteine proteinase 2 0.1207 0.0885 0.3931
Plasmodium falciparum serine repeat antigen 1 0.0686 0.0496 0.3405
Plasmodium vivax hypothetical protein, conserved 0.0674 0.0487 0.1536
Leishmania major programmed cell death 6 protein-like protein 0.0666 0.0481 0.1398
Entamoeba histolytica cysteine proteinase, putative 0.1972 0.1455 0.6475
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Toxoplasma gondii hypothetical protein 0.0035 0.0011 0.0028
Schistosoma mansoni hypothetical protein 0.0147 0.0095 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0011 0.001
Echinococcus multilocularis regulator of G protein signaling 7 0.0036 0.0011 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0686 0.0496 0.1436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0025 0.0003 0.0003
Giardia lamblia Cathepsin L-like protease 0.0686 0.0496 0.1435
Trypanosoma brucei I/6 autoantigen 0.0666 0.0481 0.1398
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0031 0.003
Echinococcus granulosus subfamily T1A non peptidase ue 0.0025 0.0003 0.0002
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0686 0.0496 0.3405
Trypanosoma brucei calpain-like protein, putative 0.4272 0.3168 0.9223
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0006 0.0466
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0064 0.0032 0.0031
Giardia lamblia Cysteine protease 0.0686 0.0496 0.1435
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0666 0.0481 0.2132
Schistosoma mansoni cellular tumor antigen P53 0.0039 0.0014 0.0013
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0025 0.0003 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.9223
Brugia malayi Cathepsin L-like precursor 0.1451 0.1066 0.1065
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Onchocerca volvulus 0.0035 0.0011 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Echinococcus granulosus axis inhibition protein axin 0.0036 0.0011 0.001
Giardia lamblia Cathepsin B precursor 0.0686 0.0496 0.1435
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 1.2095 0.8998 0.8998
Plasmodium falciparum calpain 0.124 0.0909 0.6247
Schistosoma mansoni myosin regulatory light chain 0.008 0.0044 0.0043
Trypanosoma brucei proteasome alpha 7 subunit 0.0025 0.0003 0.0006
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.006 0.003 0.0028
Echinococcus multilocularis regulator of G protein signaling 3 0.0036 0.0011 0.001
Leishmania major hypothetical protein, conserved 0.0035 0.0011 0.0028
Schistosoma mansoni caspase-3 (C14 family) 0.0135 0.0086 0.0084
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0025 0.0003 0.0002
Leishmania major hypothetical protein, conserved 0.124 0.0909 0.2644
Loa Loa (eye worm) hypothetical protein 0.8397 0.6242 0.6242
Brugia malayi proteasome subunit beta type 3 0.0025 0.0003 0.0002
Brugia malayi cathepsin Z-like cysteine proteinase 0.0686 0.0496 0.0495
Echinococcus multilocularis cathepsin L cysteine protease 0.1972 0.1455 0.1453
Schistosoma mansoni cathepsin C 0.0686 0.0496 0.0495
Toxoplasma gondii proteasome beta subunit 0.0025 0.0003 0.0006
Trypanosoma cruzi calmodulin, putative 0.0666 0.0481 0.048
Schistosoma mansoni reticulocalbin 0.0674 0.0487 0.0486
Echinococcus granulosus Myosin regulatory light chain 0.008 0.0044 0.0043
Brugia malayi Papain family cysteine protease containing protein 0.0686 0.0496 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0686 0.0496 0.1436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Giardia lamblia Cysteine protease 0.0686 0.0496 0.1435
Echinococcus multilocularis gamma secretase subunit aph 1 0.0117 0.0072 0.0071
Plasmodium vivax hypothetical protein, conserved 0.0064 0.0033 0.01
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0033 0.0009 0.0008
Trichomonas vaginalis calmodulin, putative 0.0666 0.0481 0.1394
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0006 0.0466
Trypanosoma cruzi calmodulin, putative 0.0666 0.0481 0.048
Trypanosoma brucei antigen, putative 0.4272 0.3168 0.9223
Loa Loa (eye worm) cathepsin B 0.463 0.3435 0.3435
Brugia malayi Papain family cysteine protease containing protein 0.1972 0.1455 0.1454
Brugia malayi Cytochrome P450 family protein 0.0029 0.0007 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0022 0.1803
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0025 0.0003 0.0002
Onchocerca volvulus 0.0039 0.0014 0.0024
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0025 0.0003 0.0002
Giardia lamblia Proteasome subunit beta type 1 0.0064 0.0032 0.0084
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0666 0.0481 0.048
Entamoeba histolytica calmodulin, putative 0.008 0.0044 0.0182
Loa Loa (eye worm) hypothetical protein 0.0036 0.0011 0.0011
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.4272 0.3168 0.3167
Brugia malayi A-kinase anchor protein 10, precursor 0.0036 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0522 0.0374 0.0374
Trypanosoma brucei Calpain-like protein 2 0.124 0.0909 0.2644
Echinococcus granulosus proteasome subunit beta type 6 0.0025 0.0003 0.0002
Echinococcus granulosus expressed protein 0.0693 0.0502 0.05
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.124 0.0909 0.0908
Entamoeba histolytica grainin, putative 0.0674 0.0487 0.2159
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Trypanosoma brucei calpain-like protein, putative 0.4272 0.3168 0.9223
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0686 0.0496 0.1436
Giardia lamblia Cathepsin B precursor 0.0686 0.0496 0.1435
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0031 0.008
Schistosoma mansoni rab 0.0666 0.0481 0.048
Trypanosoma brucei mitochondrial calcium uptake 1 0.0666 0.0481 0.1398
Brugia malayi Neuronal calcium sensor family protein 1 0.008 0.0044 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0686 0.0496 0.1436
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0686 0.0496 0.1435
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0011 0.0028
Toxoplasma gondii microneme protein MIC4 0.0035 0.0011 0.0028
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Toxoplasma gondii EF hand domain-containing protein 0.0666 0.0481 0.1398
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0025 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0011 0.0011
Toxoplasma gondii hypothetical protein 0.124 0.0909 0.2644
Brugia malayi regulator of G-protein signaling egl-10 0.0036 0.0011 0.001
Loa Loa (eye worm) PAS-3 protein 0.0025 0.0003 0.0003
Toxoplasma gondii cathepsin CPL 0.1972 0.1455 0.4232
Trypanosoma brucei centrin, putative 0.0666 0.0481 0.1398
Brugia malayi Cathepsin L-like precursor 0.1972 0.1455 0.1454
Brugia malayi Cathepsin L-like precursor 0.1451 0.1066 0.1065
Echinococcus multilocularis programmed cell death protein 6 0.0088 0.005 0.0049
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0031 0.0029
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.9223
Schistosoma mansoni mitochondrial solute carrier 0.0666 0.0481 0.048
Echinococcus granulosus calcium uptake protein 1 0.0674 0.0487 0.0486
Echinococcus multilocularis calmodulin 0.0666 0.0481 0.048
Onchocerca volvulus 0.008 0.0044 0.0081
Trypanosoma brucei metacaspase 0.0064 0.0033 0.0091
Echinococcus granulosus cathepsin L cysteine proteinase 0.1972 0.1455 0.1453
Schistosoma mansoni neuronal calcium sensor 0.0666 0.0481 0.048
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Echinococcus multilocularis regulator of G protein signaling 0.0036 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 1.344 1 1
Trypanosoma brucei caltractin, putative 0.0746 0.0541 0.157
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0025 0.0003 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0092 0.0092
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.4272 0.3168 0.3167
Trypanosoma cruzi calpain cysteine peptidase, putative 0.124 0.0909 0.0908
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.013 0.0082 0.008
Leishmania major protein kinase, putative 0.0667 0.0482 0.1399
Leishmania major calcineurin B subunit, putative 0.0666 0.0481 0.1398
Plasmodium vivax proteasome subunit beta type-3, putative 0.0025 0.0003 0.0008
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.006 0.003 0.0028
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0025 0.0003 0.0002
Echinococcus granulosus EF HAND 1 calcium binding site 0.0666 0.0481 0.048
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0033 0.0009 0.0009
Trypanosoma cruzi cruzipain precursor, putative 0.22 0.1624 0.1623
Plasmodium falciparum serine repeat antigen 5 0.0686 0.0496 0.3405
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0686 0.0496 0.0495
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Brugia malayi Cytochrome P450 family protein 0.0049 0.0021 0.002
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0025 0.0003 0.0002
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0064 0.0033 0.0091
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 1.2095 0.8998 0.8998
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0666 0.0481 0.048
Onchocerca volvulus 0.1451 0.1066 0.2002
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0019 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1972 0.1455 0.423
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0025 0.0003 0.0006
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0666 0.0481 0.1394
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0025 0.0003 0.0002
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0025 0.0003 0.0002
Trypanosoma cruzi major cysteine proteinase, putative 0.0913 0.0665 0.0664
Loa Loa (eye worm) hypothetical protein 0.008 0.0044 0.0044
Toxoplasma gondii centrin family protein 0.008 0.0044 0.0125
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Toxoplasma gondii EF hand domain-containing protein 0.008 0.0044 0.0125
Schistosoma mansoni Mername-AA248 (C02 family) 0.4272 0.3168 0.3167
Toxoplasma gondii calmodulin, putative 0.008 0.0044 0.0125
Entamoeba histolytica cysteine proteinase, putative 0.1207 0.0885 0.3931
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0011 0.0025
Brugia malayi calpain 7 0.4272 0.3168 0.3167
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Brugia malayi PXA domain containing protein 0.0036 0.0011 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0666 0.0481 0.1394
Trypanosoma brucei calpain-like protein, putative 0.4272 0.3168 0.9223
Brugia malayi 20S proteasome alpha5 subunit 0.0025 0.0003 0.0002
Trypanosoma cruzi cysteine proteinase, putative 0.1207 0.0885 0.0883
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0667 0.0482 0.1399
Echinococcus multilocularis programmed cell death protein 0.0746 0.0541 0.0539
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0017 0.0017
Echinococcus multilocularis neuronal calcium sensor 0.0666 0.0481 0.048
Schistosoma mansoni hypothetical protein 0.0035 0.0011 0.0009
Brugia malayi cathepsin L precursor 0.0686 0.0496 0.0495
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Onchocerca volvulus 0.0193 0.0129 0.0239
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0006 0.0005
Echinococcus multilocularis regulator of G protein signaling 3 0.0036 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.7157 0.5318 0.5318
Trichomonas vaginalis calcium binding protein, putative 0.0666 0.0481 0.1394
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0049 0.0022 0.1864
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Echinococcus multilocularis calcium uptake protein 1 0.0674 0.0487 0.0486
Echinococcus granulosus regulator of G protein signaling 7 0.0036 0.0011 0.001
Toxoplasma gondii peptidase, T1 family protein 0.0025 0.0003 0.0006
Schistosoma mansoni gamma-secretase subunit aph-1 0.0117 0.0072 0.0071
Entamoeba histolytica calmodulin, putative 0.0666 0.0481 0.2132
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0177 0.0117 0.0115
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0686 0.0496 0.3405
Schistosoma mansoni reticulocalbin 0.0666 0.0481 0.048
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.124 0.0909 0.0908
Echinococcus granulosus proteasome prosome macropain subunit beta 0.006 0.003 0.0028
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0064 0.0032 0.0031
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0025 0.0003 0.0002
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.008 0.0044 0.0081
Trypanosoma cruzi metacaspase 5, putative 0.0164 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0007
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0036 0.0012 0.0011
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0686 0.0496 0.1563
Plasmodium vivax vivapain-2 0.1972 0.1455 0.459
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0036 0.0011 0.001
Echinococcus granulosus microtubule associated protein 2 0.0737 0.0534 0.0533
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Trichomonas vaginalis calmodulin, putative 0.0666 0.0481 0.1394
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0025 0.0003 0.0003
Onchocerca volvulus 0.1972 0.1455 0.2733
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.124 0.0909 0.2644
Trichomonas vaginalis centrin, putative 0.008 0.0044 0.0121
Echinococcus multilocularis survival motor neuron protein 1 0.0358 0.0252 0.025
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0177 0.0117 0.0115
Loa Loa (eye worm) hypothetical protein 0.0522 0.0374 0.0374
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0024 0.0003 0.0005
Trypanosoma cruzi metacaspase, putative 0.0164 0.0107 0.0106
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.124 0.0909 0.264
Loa Loa (eye worm) myosin Light Chain family member 0.0088 0.005 0.005
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0686 0.0496 0.0495
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0031 0.003
Echinococcus granulosus gamma secretase subunit aph 1 0.0117 0.0072 0.0071
Echinococcus granulosus geminin 0.0147 0.0095 0.0093
Plasmodium vivax proteasome subunit beta type-2, putative 0.006 0.003 0.0092
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0025 0.0003 0.0298
Leishmania major hypothetical protein, conserved 0.0674 0.0487 0.1416
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1972 0.1455 0.1455
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0025 0.0003 0.0002
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0025 0.0003 0.0006
Brugia malayi Heterochromatin protein 1 0.0061 0.003 0.0029
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Trypanosoma cruzi cysteine peptidase, putative 0.1972 0.1455 0.1454
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0064 0.0032 0.0086
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0064 0.0032 0.0031
Brugia malayi regulator of G-protein signaling rgs-7 0.0036 0.0011 0.001
Echinococcus granulosus programmed cell death protein 6 0.0088 0.005 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.124 0.0909 0.264
Toxoplasma gondii aldehyde dehydrogenase 0.0049 0.0022 0.006
Schistosoma mansoni cathepsin s 0.0522 0.0374 0.0372
Brugia malayi Cathepsin L-like precursor 0.1972 0.1455 0.1454
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.4272 0.3168 0.3167
Trypanosoma cruzi centrin-3 0.0746 0.0541 0.0539
Leishmania major cathepsin L-like protease 0.1972 0.1455 0.4232
Echinococcus multilocularis chromobox protein 1 0.0061 0.003 0.0029
Brugia malayi Cathepsin L-like precursor 0.1972 0.1455 0.1454
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Echinococcus multilocularis calpain 5 0.4272 0.3168 0.3167
Toxoplasma gondii cathepsin CPC2 0.0686 0.0496 0.144
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0025 0.0003 0.0003
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0025 0.0003 0.0018
Toxoplasma gondii PAN domain-containing protein 0.0035 0.0011 0.0028
Echinococcus multilocularis EF hand domain containing family member A2 0.0666 0.0481 0.048
Schistosoma mansoni calpain C (C02 family) 0.4272 0.3168 0.3167
Brugia malayi calpain 5 0.124 0.0909 0.0908
Brugia malayi cathepsin F-like cysteine proteinase 0.0686 0.0496 0.0495
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0006 0.0015
Trichomonas vaginalis caltractin, putative 0.008 0.0044 0.0121
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0006 0.0015
Toxoplasma gondii calcium-dependent protein kinase 0.0675 0.0488 0.1417
Trichomonas vaginalis calpain, putative 0.124 0.0909 0.264
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0025 0.0003 0.0008
Brugia malayi Cathepsin L-like precursor 0.1972 0.1455 0.1454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1451 0.1066 0.3097
Schistosoma mansoni cathepsin F (C01 family) 0.1972 0.1455 0.1453
Trypanosoma brucei metacaspase 5, putative 0.0164 0.0107 0.0308
Echinococcus granulosus survival motor neuron protein 1 0.0358 0.0252 0.025
Echinococcus multilocularis beta adrenergic receptor kinase 0.0036 0.0012 0.001
Echinococcus granulosus proteasome subunit beta type 7 0.0025 0.0003 0.0002
Onchocerca volvulus 0.1972 0.1455 0.2733
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1207 0.0885 0.2572
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0036 0.0011 0.0011
Toxoplasma gondii proteasome subunit beta type, putative 0.0177 0.0117 0.0336
Trypanosoma cruzi metacaspase, putative 0.0164 0.0107 0.0106
Leishmania major centrin, putative,caltractin, putative 0.0666 0.0481 0.1398
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0686 0.0496 0.1436
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0025 0.0003 0.0002
Leishmania major cathepsin L-like protease 0.1972 0.1455 0.4232
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.006 0.003 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0686 0.0496 0.1436
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0025 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0025 0.0003 0.0018
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0034 0.001 0.0017
Toxoplasma gondii troponin c, isotype gamma, putative 0.0666 0.0481 0.1398
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Echinococcus multilocularis calpain 7 (C02 family) 0.4272 0.3168 0.3167
Echinococcus multilocularis calmodulin 0.0666 0.0481 0.048
Plasmodium vivax ataxin-2 like protein, putative 0.0022 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0025 0.0003 0.0002
Leishmania major cathepsin L-like protease 0.22 0.1624 0.4726
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0686 0.0496 0.0495
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0006 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0686 0.0496 0.2197
Trypanosoma cruzi conserved protein 0.124 0.0909 0.0908
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0667 0.0482 0.048
Leishmania major calmodulin, putative 0.0666 0.0481 0.1398
Giardia lamblia Cathepsin L precursor 0.0686 0.0496 0.1435
Entamoeba histolytica hypothetical protein, conserved 0.0674 0.0487 0.2159
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0031 0.0081
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.124 0.0909 0.2644
Brugia malayi calpain D 0.124 0.0909 0.0908
Giardia lamblia Hypothetical protein 0.0686 0.0496 0.1435
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Echinococcus multilocularis expressed protein 0.0693 0.0502 0.05
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0006 0.0247
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0035 0.0011 0.0028
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1207 0.0885 0.0883
Trypanosoma cruzi cysteine peptidase, putative 0.22 0.1624 0.1623
Plasmodium falciparum centrin-1 0.0666 0.0481 0.3304
Echinococcus granulosus axis inhibition protein axin 0.0036 0.0011 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.22 0.1624 0.4726
Trichomonas vaginalis centrin, putative 0.008 0.0044 0.0121
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0025 0.0003 0.0002
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0674 0.0487 0.0486
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0025 0.0003 0.0002
Echinococcus granulosus cathepsin L 0.1207 0.0885 0.0883
Schistosoma mansoni regulator of G protein signaling 0.0036 0.0011 0.001
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0686 0.0496 0.1563
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1972 0.1455 0.423
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.124 0.0909 0.264
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0024 0.0003 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0037 0.0012 0.0027
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0666 0.0481 0.1398
Brugia malayi calpain family protein 1 1.1429 0.8502 0.8501
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0006 0.0466
Schistosoma mansoni cathepsin S (C01 family) 0.0686 0.0496 0.0495
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0686 0.0496 0.0495
Leishmania major proteasome beta 5 subunit, putative 0.0177 0.0117 0.0336
Plasmodium vivax proteasome subunit beta type-7, putative 0.0025 0.0003 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Trichomonas vaginalis calcineurin B subunit, putative 0.0674 0.0487 0.1412
Leishmania major kinesin, putative 0.3032 0.2244 0.6531
Trypanosoma brucei calmodulin, putative 0.0666 0.0481 0.1398
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0025 0.0003 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Echinococcus multilocularis caspase 8 0.0064 0.0033 0.0031
Leishmania major proteasome beta 2 subunit, putative 0.0025 0.0003 0.0006
Brugia malayi proteasome subunit alpha type 6 0.0025 0.0003 0.0002
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0667 0.0482 0.1518
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 1.2095 0.8998 0.8998
Trypanosoma cruzi cysteine peptidase, putative 0.0522 0.0374 0.0372
Leishmania major calmodulin-like protein 0.0666 0.0481 0.1398
Echinococcus granulosus proteasome subunit alpha type 6 0.0025 0.0003 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0031 0.0029
Trichomonas vaginalis hypothetical protein 0.124 0.0909 0.264
Brugia malayi RasGEF domain containing protein 0.008 0.0044 0.0043
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0032 0.0031
Onchocerca volvulus 0.7157 0.5318 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.008 0.0044 0.0081
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0025 0.0003 0.0002
Plasmodium falciparum proteasome subunit beta type-4 0.0025 0.0003 0.0018
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0064 0.0032 0.0091
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0025 0.0003 0.0008
Leishmania major proteasome alpha 7 subunit, putative 0.0025 0.0003 0.0006
Toxoplasma gondii cathepsin B 0.463 0.3435 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1972 0.1455 0.423
Loa Loa (eye worm) cysteine protease 0.1972 0.1455 0.1455
Brugia malayi Proteasome A-type and B-type family protein 0.0025 0.0003 0.0002
Plasmodium falciparum serine repeat antigen 3 0.0686 0.0496 0.3405
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0666 0.0481 0.048
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0025 0.0003 0.0002
Loa Loa (eye worm) PAN domain-containing protein 0.0035 0.0011 0.0011
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0686 0.0496 0.2197
Trichomonas vaginalis myosin light chain 1, putative 0.0666 0.0481 0.1394
Leishmania major hypothetical protein, unknown function 0.124 0.0909 0.2644
Brugia malayi calcium-binding protein 0.0666 0.0481 0.048
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0667 0.0482 0.048
Onchocerca volvulus 0.0666 0.0481 0.0902
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0025 0.0003 0.0002
Brugia malayi Regulator of G protein signaling domain containing protein 0.0036 0.0011 0.001
Echinococcus multilocularis chromobox protein 1 0.0061 0.003 0.0029
Leishmania major calmodulin, putative 0.0666 0.0481 0.1398
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0033 0.0087
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0025 0.0003 0.0006
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0674 0.0487 0.0486
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0686 0.0496 0.0496
Loa Loa (eye worm) proteasome subunit beta type 1 0.0064 0.0032 0.0032
Entamoeba histolytica cysteine proteinase, putative 0.1972 0.1455 0.6475
Echinococcus multilocularis cathepsin L 0.1207 0.0885 0.0883
Trichomonas vaginalis calcium binding protein, putative 0.008 0.0044 0.0121
Brugia malayi Papain family cysteine protease containing protein 0.1207 0.0885 0.0883
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0025 0.0003 0.0002
Giardia lamblia Cathepsin L precursor 0.0686 0.0496 0.1435
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0032 0.0031
Leishmania major cathepsin L-like protease 0.1972 0.1455 0.4232
Entamoeba histolytica cysteine protease, putative 0.1207 0.0885 0.3931
Entamoeba histolytica cysteine protease, putative 0.0686 0.0496 0.2197
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0006 0.0537
Echinococcus multilocularis cathepsin L 0.0686 0.0496 0.0495
Trypanosoma cruzi cysteine peptidase, putative 0.22 0.1624 0.1623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0686 0.0496 0.1436
Loa Loa (eye worm) PXA domain-containing protein 0.0036 0.0011 0.0011
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0036 0.0012 0.0012
Loa Loa (eye worm) TK/ROR protein kinase 0.0035 0.0011 0.0011
Leishmania major proteasome alpha 7 subunit, putative 0.0025 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.0147 0.0095 0.0093
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Brugia malayi Probable myosin regulatory light chain 0.0088 0.005 0.0049
Echinococcus multilocularis EF hand domain containing family member A2 0.0674 0.0487 0.0486
Echinococcus granulosus tissue type plasminogen activator 0.0035 0.0011 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0012 0.001
Echinococcus granulosus centrin 2 0.0666 0.0481 0.048
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0025 0.0003 0.0003
Plasmodium falciparum serine repeat antigen 8 0.0686 0.0496 0.3405
Echinococcus granulosus calpain 7 C02 family 0.4272 0.3168 0.3167
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0025 0.0003 0.0006
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0007 0.0016
Giardia lamblia Cathepsin B precursor 0.0686 0.0496 0.1435
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1972 0.1455 0.1453
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0006 0.0247
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0025 0.0003 0.0018
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0025 0.0003 0.5
Toxoplasma gondii EFHC1, putative 0.0666 0.0481 0.1398
Toxoplasma gondii PAN/Apple domain-containing protein 0.0035 0.0011 0.0028
Echinococcus multilocularis axis inhibition protein axin 0.0036 0.0011 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.0908
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0025 0.0003 0.0002
Giardia lamblia Cathepsin B precursor 0.463 0.3435 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0135 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0025 0.0003 0.0018
Trichomonas vaginalis calpain, putative 0.124 0.0909 0.264
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.124 0.0909 0.264
Loa Loa (eye worm) hypothetical protein 0.008 0.0044 0.0044
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 1.344 1 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0021 0.0021
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0001 0.0003
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0025 0.0003 0.0002
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0025 0.0003 0.0018
Trypanosoma brucei cysteine peptidase, putative 0.124 0.0909 0.2644
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0025 0.0003 0.0002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.124 0.0909 0.0908
Echinococcus multilocularis calpain 0.4272 0.3168 0.3167
Trypanosoma cruzi cysteine protease, putative 0.1207 0.0885 0.0883
Onchocerca volvulus 0.0674 0.0487 0.0914
Leishmania major calpain protease-like protein 0.124 0.0909 0.2644
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0686 0.0496 0.1563
Loa Loa (eye worm) hypothetical protein 0.124 0.0909 0.0909
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0686 0.0496 0.0495
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0025 0.0003 0.0003
Plasmodium vivax vivapain-3 0.1207 0.0885 0.279
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0025 0.0003 0.0006
Toxoplasma gondii microneme protein, putative 0.0035 0.0011 0.0028
Schistosoma mansoni calmodulin 0.0666 0.0481 0.048
Echinococcus granulosus cathepsin b 1.344 1 1
Trichomonas vaginalis calmodulin, putative 0.0666 0.0481 0.1394
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0686 0.0496 0.1435
Giardia lamblia Encystation-specific protease 0.0686 0.0496 0.1435
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1207 0.0885 0.0883
Schistosoma mansoni calmodulin 0.0666 0.0481 0.048
Onchocerca volvulus Cathepsin L homolog 0.0686 0.0496 0.093
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Trypanosoma cruzi metacaspase, putative 0.0164 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 1.1429 0.8502 0.8502
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.124 0.0909 0.0908
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0003 0.0002
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1972 0.1455 1
Echinococcus multilocularis Myosin regulatory light chain 0.008 0.0044 0.0043
Schistosoma mansoni survival motor neuron protein 0.0073 0.0039 0.0038
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0025 0.0003 0.0002
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0001 0.0075
Brugia malayi proteasome subunit alpha type 4 0.0025 0.0003 0.0002
Toxoplasma gondii microneme protein MIC17A 0.0035 0.0011 0.0028
Loa Loa (eye worm) hypothetical protein 0.0686 0.0496 0.0496
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0522 0.0374 0.0374
Loa Loa (eye worm) RGS-3 protein 0.0036 0.0011 0.0011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0686 0.0496 0.0495
Plasmodium vivax serine-repeat antigen (SERA) 0.0686 0.0496 0.1563
Trichomonas vaginalis calcium binding protein, putative 0.0666 0.0481 0.1394
Trypanosoma brucei kinesin, putative 0.3032 0.2244 0.6531
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0025 0.0003 0.0002
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0022 0.002
Brugia malayi PAN domain containing protein 0.0035 0.0011 0.001
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0025 0.0003 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0044 0.0121
Brugia malayi Cathepsin L-like cysteine proteinase 0.1451 0.1066 0.1065
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1972 0.1455 0.423
Brugia malayi proteasome subunit alpha type 1 0.0025 0.0003 0.0002
Trypanosoma cruzi kinesin, putative 0.3032 0.2244 0.2243
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0033 0.0087
Schistosoma mansoni calmodulin related calcium binding protein 0.0666 0.0481 0.048
Trypanosoma cruzi cysteine peptidase C (CPC), putative 1.344 1 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.124 0.0909 0.0908
Loa Loa (eye worm) hypothetical protein 0.0036 0.0011 0.0011
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0025 0.0003 0.0002
Plasmodium falciparum cysteine proteinase falcipain 1 0.1207 0.0885 0.6079
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0686 0.0496 0.0496
Echinococcus granulosus calumenin 0.0674 0.0487 0.0486
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0025 0.0003 0.0006
Trichomonas vaginalis centrin, putative 0.008 0.0044 0.0121
Trypanosoma cruzi major cysteine proteinase, putative 0.0686 0.0496 0.0495
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0177 0.0117 0.0331
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0025 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0011 0.0025
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.124 0.0909 0.2644
Leishmania major proteasome beta-1 subunit, putative 0.0025 0.0003 0.0006
Echinococcus multilocularis caspase 2 0.0064 0.0033 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.001 0.0022
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1207 0.0885 0.0883
Entamoeba histolytica calcium-binding protein, putative 0.0666 0.0481 0.2132
Trypanosoma cruzi cysteine proteinase, putative 0.1207 0.0885 0.0883
Entamoeba histolytica hypothetical protein 0.0686 0.0496 0.2197

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0085 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 5.2213 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 6.3096 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 7.3753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.1093 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (binding) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.081 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate. (Class of assay: confirmatory) [Related pubchem assays: 1472, 1467 ] ChEMBL. No reference
Potency (functional) 32.6427 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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