Detailed information for compound 1408893

Basic information

Technical information
  • TDR Targets ID: 1408893
  • Name: N-(2-fluorophenyl)-2-[3-(2-methoxybenzoyl)-7- methyl-4-oxo-1,8-naphthyridin-1-yl]acetamide
  • MW: 445.442 | Formula: C25H20FN3O4
  • H donors: 1 H acceptors: 4 LogP: 3.89 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1C(=O)c1cn(CC(=O)Nc2ccccc2F)c2c(c1=O)ccc(n2)C
  • InChi: 1S/C25H20FN3O4/c1-15-11-12-17-24(32)18(23(31)16-7-3-6-10-21(16)33-2)13-29(25(17)27-15)14-22(30)28-20-9-5-4-8-19(20)26/h3-13H,14H2,1-2H3,(H,28,30)
  • InChiKey: BYWFJOOXQDFVTK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2-fluorophenyl)-2-[3-[(2-methoxyphenyl)-oxomethyl]-7-methyl-4-oxo-1,8-naphthyridin-1-yl]acetamide
  • N-(2-fluorophenyl)-2-[4-keto-3-(2-methoxybenzoyl)-7-methyl-1,8-naphthyridin-1-yl]acetamide
  • N-(2-fluorophenyl)-2-[3-(2-methoxyphenyl)carbonyl-7-methyl-4-oxo-1,8-naphthyridin-1-yl]ethanamide
  • E999-1467
  • NCGC00127744-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0301 0.121 0.121
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0906 0.2213
Giardia lamblia Transglutaminase/protease, putative 0.0544 0.2248 0.6021
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0035 0.0073 0.0073
Echinococcus multilocularis enteropeptidase 0.0035 0.0073 0.0073
Loa Loa (eye worm) calpain 5 0.0438 0.1797 0.1797
Schistosoma mansoni hypothetical protein 0.0544 0.2248 0.2248
Echinococcus granulosus dnaJ subfamily B 0.0412 0.1683 0.1683
Onchocerca volvulus 0.0035 0.0073 0.0109
Mycobacterium ulcerans hypothetical protein 0.0036 0.0076 0.0256
Entamoeba histolytica calpain large subunit domain III containing protein 0.0438 0.1797 0.4382
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0066 0.0208 0.0208
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0015 0.0015
Echinococcus granulosus expressed protein 0.0797 0.3329 0.3329
Trypanosoma brucei histone deacetylase, putative 0.01 0.0352 0.0517
Schistosoma mansoni cathepsin F (C01 family) 0.0976 0.4094 0.4094
Plasmodium falciparum serine repeat antigen 6 0.0234 0.0922 0.2253
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1588 0.6712 1
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0105 0.0105
Toxoplasma gondii calcium-dependent protein kinase 0.01 0.035 0.0522
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0076 0.0125
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0674 0.2805 1
Toxoplasma gondii aldehyde dehydrogenase 0.0127 0.0468 0.0697
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0024 0.0024 0.0059
Entamoeba histolytica cysteine proteinase, putative 0.0534 0.2208 0.5388
Echinococcus multilocularis calumenin 0.01 0.035 0.035
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0186 0.0277
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0568 0.2351 0.2351
Loa Loa (eye worm) hypothetical protein 0.0098 0.0343 0.0343
Plasmodium vivax proteasome subunit beta type-5, putative 0.0086 0.0289 0.0707
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0086 0.0289 0.0285
Plasmodium vivax hypothetical protein, conserved 0.01 0.035 0.0856
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0208 0.0203
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0068 0.0068
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0015 0.0015
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0015
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0105 0.01
Echinococcus multilocularis geminin 0.0169 0.0646 0.0646
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0099 0.0099
Trypanosoma brucei Calpain-like protein 1.1 0.0188 0.0729 0.108
Echinococcus granulosus cathepsin l1 0.0675 0.2808 0.2808
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0099 0.0099
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0362 0.1473 0.1473
Toxoplasma gondii ABC1 family protein 0.0036 0.0076 0.0114
Leishmania major hypothetical protein, conserved 0.0036 0.0076 0.0107
Echinococcus multilocularis histone deacetylase 3 0.0089 0.0305 0.0305
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Echinococcus multilocularis programmed cell death protein 0.0098 0.0343 0.0343
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1661 0.7023 0.7023
Schistosoma mansoni hypothetical protein 0.0098 0.0343 0.0343
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0076 0.0076
Loa Loa (eye worm) proteasome subunit beta type 1 0.0066 0.0208 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0234 0.0922 0.2253
Brugia malayi PXA domain containing protein 0.0041 0.0099 0.0099
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0015 0.0015
Brugia malayi prolyl oligopeptidase family protein 0.0824 0.3445 0.3445
Brugia malayi beta-lactamase family protein 0.0036 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0169 0.0646 0.0646
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0319 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0241
Echinococcus multilocularis neurocalcin 0.0098 0.0343 0.0343
Echinococcus granulosus caspase 2 0.0092 0.0315 0.0315
Loa Loa (eye worm) cysteine protease 0.0976 0.4094 0.4094
Leishmania major cathepsin L-like protease 0.0976 0.4094 0.6096
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1358 0.573 1
Trypanosoma brucei cysteine peptidase, putative 0.0188 0.0729 0.108
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0099 0.0099
Trichomonas vaginalis calpain, putative 0.0188 0.0729 0.178
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Plasmodium vivax centrin-1, putative 0.0098 0.0343 0.0839
Entamoeba histolytica grainin, putative 0.01 0.035 0.0845
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Giardia lamblia Cysteine protease 0.0234 0.0922 0.2463
Giardia lamblia Cathepsin B precursor 0.0234 0.0922 0.2463
Echinococcus granulosus gamma secretase subunit aph 1 0.0243 0.096 0.096
Trypanosoma brucei calmodulin, putative 0.0098 0.0343 0.0505
Loa Loa (eye worm) hypothetical protein 0.0234 0.0922 0.0922
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0076
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0234 0.0922 0.2253
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0076 0.0076
Schistosoma mansoni cathepsin F (C01 family) 0.0675 0.2808 0.2808
Plasmodium falciparum serine repeat antigen 5 0.0234 0.0922 0.2253
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0015
Trypanosoma cruzi prolyl endopeptidase 0.1588 0.6712 0.6711
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0627 0.2602 0.2598
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0063 0.0195 0.0195
Plasmodium vivax histone deacetylase, putative 0.01 0.0352 0.0859
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0194 0.0194
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0328 0.0323
Entamoeba histolytica hypothetical protein 0.0041 0.0099 0.023
Echinococcus multilocularis calcium uptake protein 1 0.01 0.035 0.035
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0627 0.2602 0.3872
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1759 0.7443 0.7443
Schistosoma mansoni calpain C (C02 family) 0.0627 0.2602 0.2602
Entamoeba histolytica cysteine protease, putative 0.0234 0.0922 0.2244
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0086 0.0289 0.0285
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0105 0.0105
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0568 0.2351 0.3498
Leishmania major kinesin, putative 0.0438 0.1797 0.2672
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0674 0.2805 0.2802
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Brugia malayi beta-lactamase 0.0036 0.0076 0.0076
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.0305 0.03
Schistosoma mansoni calpain-2 (C02 family) 0.0188 0.0729 0.0729
Schistosoma mansoni centrin 0.0098 0.0343 0.0343
Toxoplasma gondii preprocathepsin c precursor, putative 0.0234 0.0922 0.1374
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.01 0.01
Echinococcus multilocularis calpain family protein 1, d 0.1223 0.515 0.515
Brugia malayi gamma-secretase subunit aph-1 0.0243 0.096 0.096
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Trichomonas vaginalis calmodulin-2, putative 0.0098 0.0343 0.0839
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.2598
Entamoeba histolytica prolyl oligopeptidase family protein 0.023 0.0906 0.2204
Onchocerca volvulus 0.0976 0.4094 0.6099
Giardia lamblia Cathepsin B precursor 0.0234 0.0922 0.2463
Onchocerca volvulus 0.0035 0.0073 0.0109
Giardia lamblia Cathepsin L precursor 0.0234 0.0922 0.2463
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0194 0.0289
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0194 0.0194
Brugia malayi Histone deacetylase family protein 0.01 0.0352 0.0352
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0107 0.0103
Plasmodium vivax calpain, putative 0.0627 0.2602 0.6355
Echinococcus multilocularis cathepsin L cysteine protease 0.0976 0.4094 0.4094
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0189 0.0731 0.1084
Loa Loa (eye worm) hypothetical protein 0.0234 0.0922 0.0922
Loa Loa (eye worm) hypothetical protein 0.0246 0.0977 0.0977
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0188 0.0729 0.178
Loa Loa (eye worm) hypothetical protein 0.0234 0.0922 0.0922
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0188 0.0729 0.0729
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0099 0.0099
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0824 0.3445 0.3445
Trypanosoma brucei calpain-like protein, putative 0.0627 0.2602 0.3872
Onchocerca volvulus 0.0092 0.0315 0.047
Trypanosoma brucei Calpain-like protein 2 0.0188 0.0729 0.108
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1759 0.7443 0.7443
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0015
Toxoplasma gondii centrin, putative 0.0098 0.0343 0.0512
Brugia malayi Cytochrome P450 family protein 0.0034 0.0068 0.0068
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0319 0.0319
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0076 0.0125
Plasmodium vivax serine-repeat antigen (SERA) 0.0234 0.0922 0.2253
Loa Loa (eye worm) hypothetical protein 0.0301 0.121 0.121
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0105 0.0256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0188 0.0729 0.0725
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0328 0.0323
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0099 0.0099
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0125
Loa Loa (eye worm) hypothetical protein 0.0229 0.0902 0.0902
Toxoplasma gondii hypothetical protein 0.023 0.0906 0.135
Echinococcus granulosus histone deacetylase 0.01 0.0352 0.0352
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Mycobacterium tuberculosis Conserved protein 0.0544 0.2248 0.3917
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0015 0.0022
Toxoplasma gondii calmodulin CAM1 0.01 0.035 0.0522
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0068 0.0095
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.1683 0.1683
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2357 1 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0015 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0194 0.0194
Echinococcus multilocularis calpain 0.0627 0.2602 0.2602
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0188 0.0729 0.0725
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0976 0.4094 0.4094
Loa Loa (eye worm) acetyltransferase 0.0175 0.0672 0.0672
Trypanosoma cruzi calmodulin, putative 0.0098 0.0343 0.0339
Trypanosoma cruzi caltractin, putative 0.0098 0.0343 0.0339
Echinococcus multilocularis cathepsin L 0.0234 0.0922 0.0922
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Trichomonas vaginalis calcium binding protein, putative 0.0098 0.0343 0.0839
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Trypanosoma brucei oligopeptidase b 0.0674 0.2805 0.4175
Trichomonas vaginalis calmodulin, putative 0.01 0.035 0.0856
Giardia lamblia Alanyl dipeptidyl peptidase 0.023 0.0906 0.2419
Loa Loa (eye worm) hypothetical protein 0.0976 0.4094 0.4094
Onchocerca volvulus 0.0035 0.0073 0.0109
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.0305 0.0744
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0015 0.0015
Mycobacterium ulcerans transglutaminase family protein 0.0544 0.2248 0.8009
Plasmodium vivax proteasome subunit beta type-1, putative 0.0066 0.0208 0.0508
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0076 0.0125
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Loa Loa (eye worm) trypsin family protein 0.0035 0.0073 0.0073
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0125 0.0295
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0125 0.0324
Giardia lamblia Hypothetical protein 0.0234 0.0922 0.2463
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0234 0.0922 0.2253
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0188 0.0729 0.0725
Loa Loa (eye worm) prolyl oligopeptidase 0.023 0.0906 0.0906
Loa Loa (eye worm) programmed cell death protein 6 0.01 0.035 0.035
Entamoeba histolytica hypothetical protein 0.0234 0.0922 0.2244
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0343 0.0839
Giardia lamblia Cysteine protease 0.0234 0.0922 0.2463
Brugia malayi Cathepsin L-like precursor 0.0976 0.4094 0.4094
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0099 0.0099
Onchocerca volvulus Cathepsin L homolog 0.0234 0.0922 0.1374
Mycobacterium ulcerans hypothetical protein 0.0544 0.2248 0.8009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0015
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0015
Onchocerca volvulus 0.0052 0.0147 0.0219
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Brugia malayi cathepsin F-like cysteine proteinase 0.0301 0.121 0.121
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.2598
Brugia malayi hypothetical protein 0.0159 0.0605 0.0605
Plasmodium vivax histone deacetylase 1, putative 0.0089 0.0305 0.0744
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0098 0.0343 0.0343
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0824 0.3445 0.5133
Brugia malayi proteasome subunit beta type 1 0.0066 0.0208 0.0208
Trypanosoma brucei protein I/6 0.0098 0.0343 0.0505
Schistosoma mansoni neuronal calcium sensor 0.0098 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0175 0.067 0.067
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0099 0.0099
Brugia malayi Histone deacetylase 1 0.0089 0.0305 0.0305
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0015 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0319 0.0319
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0041 0.01 0.0095
Trypanosoma brucei Aph-1 protein, putative 0.0095 0.0328 0.0482
Echinococcus multilocularis cpg binding protein 0.0031 0.0054 0.0054
Brugia malayi EF hand family protein 0.01 0.035 0.035
Echinococcus granulosus calumenin 0.01 0.035 0.035
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0015
Echinococcus granulosus neuronal calcium sensor 0.0098 0.0343 0.0343
Plasmodium falciparum histone deacetylase, putative 0.01 0.0352 0.0859
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0234 0.0922 0.2253
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0047 0.0047
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.01 0.035 0.0346
Trypanosoma cruzi cysteine proteinase, putative 0.0534 0.2208 0.2204
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0159 0.0605 0.0605
Schistosoma mansoni glycogen phosphorylase 0.0107 0.038 0.038
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0468 0.0468
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Trypanosoma brucei caltractin, putative 0.0098 0.0343 0.0505
Entamoeba histolytica cysteine proteinase, putative 0.0976 0.4094 1
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0674 0.2805 0.4175
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0534 0.2208 0.2208
Onchocerca volvulus 0.0035 0.0073 0.0109
Trichomonas vaginalis calpain, putative 0.0188 0.0729 0.178
Echinococcus granulosus calpain 0.0627 0.2602 0.2602
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0305 0.0744
Trypanosoma cruzi cysteine peptidase, putative 0.0301 0.121 0.1205
Brugia malayi cathepsin L precursor 0.0234 0.0922 0.0922
Loa Loa (eye worm) fibroinase 0.0976 0.4094 0.4094
Schistosoma mansoni histone deacetylase 0.0089 0.0305 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0105 0.0256
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0352 0.0347
Trypanosoma cruzi I/6 autoantigen, putative 0.0098 0.0343 0.0339
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0099 0.0099
Entamoeba histolytica calmodulin, putative 0.0098 0.0343 0.0828
Brugia malayi Cell death protein 3 precursor 0.0092 0.0315 0.0315
Trypanosoma cruzi conserved protein 0.0188 0.0729 0.0725
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0568 0.2351 0.3498
Plasmodium vivax unspecified product 0.0301 0.121 0.2955
Entamoeba histolytica glycogen phosphorylase, putative 0.0107 0.038 0.0918
Schistosoma mansoni hypothetical protein 0.0188 0.0729 0.0729
Echinococcus granulosus calcium uptake protein 1 0.01 0.035 0.035
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0086 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0076
Loa Loa (eye worm) calpain 0.0627 0.2602 0.2602
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.023 0.0906 0.0906
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0005 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0319 0.0319
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0188 0.0729 0.178
Toxoplasma gondii prolyl endopeptidase 0.1588 0.6712 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0196 0.0196
Brugia malayi PXA domain containing protein 0.0041 0.0099 0.0099
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0468 0.1655
Trypanosoma cruzi kinesin, putative 0.0438 0.1797 0.1793
Plasmodium falciparum serine repeat antigen 4 0.0234 0.0922 0.2253
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0121 0.0416
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0175 0.067 0.067
Leishmania major histone deacetylase, putative 0.0089 0.0305 0.0447
Trypanosoma cruzi major cysteine proteinase, putative 0.0334 0.1351 0.1347
Entamoeba histolytica prolyl oligopeptidase family protein 0.023 0.0906 0.2204
Echinococcus granulosus cathepsin L cysteine protease 0.0534 0.2208 0.2208
Loa Loa (eye worm) calpain family protein 1 0.1223 0.515 0.515
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0076 0.0187
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0175 0.067 0.067
Schistosoma mansoni histone deacetylase 0.0089 0.0305 0.0305
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0534 0.2208 0.3285
Trypanosoma cruzi cysteine peptidase, putative 0.1076 0.4523 0.4521
Trypanosoma brucei proteasome beta 6 subunit 0.0066 0.0208 0.0303
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0144 0.0214
Entamoeba histolytica cysteine proteinase, putative 0.0534 0.2208 0.5388
Echinococcus multilocularis histone deacetylase 6 0.01 0.0352 0.0352
Trypanosoma cruzi cruzipain precursor, putative 0.1076 0.4523 0.4521
Echinococcus multilocularis EF hand domain containing family member A2 0.01 0.035 0.035
Echinococcus multilocularis hypothetical protein 0.0627 0.2602 0.2602
Echinococcus multilocularis histone deacetylase 7 0.01 0.0352 0.0352
Leishmania major calmodulin, putative 0.0098 0.0343 0.0505
Schistosoma mansoni hypothetical protein 0.0412 0.1683 0.1683
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0099 0.0099
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0125
Giardia lamblia Hypothetical protein 0.0544 0.2248 0.6021
Mycobacterium ulcerans hypothetical protein 0.0544 0.2248 0.8009
Trichomonas vaginalis calcineurin B subunit, putative 0.0098 0.0343 0.0839
Plasmodium falciparum peptidase, putative 0.023 0.0906 0.2213
Plasmodium vivax unspecified product 0.0234 0.0922 0.2253
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.0899 0.1563
Echinococcus granulosus acylamino acid releasing enzyme 0.023 0.0906 0.0906
Trypanosoma brucei calpain-like protein, putative 0.0627 0.2602 0.3872
Schistosoma mansoni ef hand domain family member A2 0.0098 0.0343 0.0343
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0234 0.0922 0.0922
Trypanosoma cruzi 20S proteasome subunit 0.0041 0.01 0.0095
Toxoplasma gondii cathepsin CPC1 0.0234 0.0922 0.1374
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0099 0.0099
Schistosoma mansoni memapsin-2 (A01 family) 0.0444 0.1822 0.1822
Loa Loa (eye worm) hypothetical protein 0.0175 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0024
Brugia malayi Cathepsin L-like precursor 0.0976 0.4094 0.4094
Loa Loa (eye worm) hypothetical protein 0.0035 0.0073 0.0073
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0099 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0015
Plasmodium vivax proteasome subunit beta type-2, putative 0.0041 0.01 0.0244
Echinococcus multilocularis Mastin 0.0035 0.0073 0.0073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.0922 0.2253
Schistosoma mansoni caspase-7 (C14 family) 0.0092 0.0315 0.0315
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0125
Giardia lamblia Cysteine protease 0.0234 0.0922 0.2463
Brugia malayi hypothetical protein 0.0229 0.0902 0.0902
Leishmania major hypothetical protein, conserved 0.01 0.035 0.0515
Echinococcus granulosus glycogen phosphorylase 0.0107 0.038 0.038
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0066 0.0208 0.0208
Brugia malayi Pre-SET motif family protein 0.0437 0.1792 0.1792
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0675 0.2808 0.6859
Loa Loa (eye worm) hypothetical protein 0.0063 0.0194 0.0194
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Brugia malayi MH2 domain containing protein 0.0127 0.0466 0.0466
Echinococcus multilocularis cathepsin L cysteine protease 0.0976 0.4094 0.4094
Echinococcus multilocularis histone deacetylase 6 0.0106 0.0378 0.0378
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0674 0.2805 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Plasmodium vivax vivapain-1 0.0534 0.2208 0.5394
Onchocerca volvulus 0.0036 0.0076 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0234 0.0922 0.2253
Onchocerca volvulus 0.0042 0.0105 0.0156
Leishmania major programmed cell death 6 protein-like protein 0.0098 0.0343 0.0505
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0105 0.0105
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0976 0.4094 1
Echinococcus multilocularis gamma secretase subunit aph 1 0.0243 0.096 0.096
Trichomonas vaginalis peptide N-glycanase, putative 0.0544 0.2248 0.549
Schistosoma mansoni hypothetical protein 0.0175 0.067 0.067
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0139 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0035 0.0073 0.0073
Echinococcus multilocularis glycoprotein Antigen 5 0.0035 0.0073 0.0073
Trypanosoma brucei antigen, putative 0.0627 0.2602 0.3872
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Plasmodium falciparum serine repeat antigen 9 0.0234 0.0922 0.2253
Leishmania major cathepsin L-like protease 0.0976 0.4094 0.6096
Plasmodium vivax histone deacetylase, putative 0.0043 0.0107 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Echinococcus multilocularis calmodulin 0.0098 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Leishmania major C-8 sterol isomerase-like protein 0.0362 0.1473 0.2189
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0976 0.4094 0.4094
Echinococcus granulosus apoptotic protease activating factor 1 0.0092 0.0315 0.0315
Echinococcus granulosus geminin 0.0169 0.0646 0.0646
Plasmodium falciparum cysteine proteinase falcipain 1 0.0534 0.2208 0.5394
Giardia lamblia Hypothetical protein 0.01 0.035 0.0928
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.0305 0.0744
Schistosoma mansoni mitochondrial solute carrier 0.0098 0.0343 0.0343
Schistosoma mansoni hypothetical protein 0.0098 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0534 0.2208 0.5394
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0343 0.0839
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.01 0.0244
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0076 0.0107
Echinococcus multilocularis expressed protein 0.0797 0.3329 0.3329
Loa Loa (eye worm) hypothetical protein 0.0234 0.0922 0.0922
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Brugia malayi hypothetical protein 0.0246 0.0977 0.0977
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0076 0.0187
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0797 0.333 0.333
Onchocerca volvulus Cathepsin L homolog 0.0976 0.4094 0.6099
Echinococcus multilocularis prolyl endopeptidase 0.1588 0.6712 0.6712
Mycobacterium ulcerans beta-lactamase 0.0036 0.0076 0.0256
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0099 0.0099
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0098 0.0343 0.0828
Toxoplasma gondii EFHC1, putative 0.0098 0.0343 0.0512
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0099 0.0099
Trypanosoma cruzi centrin, putative 0.0098 0.0343 0.0339
Echinococcus multilocularis histone deacetylase 8 0.0043 0.0107 0.0107
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1588 0.6712 0.6712
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0015
Brugia malayi calcium-binding protein 0.0098 0.0343 0.0343
Loa Loa (eye worm) histone deacetylase 0.01 0.0352 0.0352
Onchocerca volvulus 0.0021 0.0015 0.0022
Trypanosoma cruzi cysteine proteinase, putative 0.0534 0.2208 0.2204
Trichomonas vaginalis calcium binding protein, putative 0.0098 0.0343 0.0839
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0188 0.0729 0.108
Onchocerca volvulus Deterin homolog 0.0175 0.067 0.0998
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1759 0.7443 0.7443
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0076 0.0187
Entamoeba histolytica dipeptidyl-peptidase, putative 0.023 0.0906 0.2204
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0241
Entamoeba histolytica calcium-binding protein, putative 0.0098 0.0343 0.0828
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0627 0.2602 0.2598
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0099 0.0099
Entamoeba histolytica dipeptidyl-peptidase, putative 0.023 0.0906 0.2204
Brugia malayi Cathepsin L-like precursor 0.0976 0.4094 0.4094
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.2598
Trypanosoma cruzi hypothetical protein, conserved 0.023 0.0906 0.0902
Onchocerca volvulus 0.0036 0.0076 0.0114
Brugia malayi carbohydrate phosphorylase 0.0107 0.038 0.038
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0234 0.0922 0.2253
Toxoplasma gondii cathepsin CPC2 0.0234 0.0922 0.1374
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Brugia malayi calpain family protein 1 0.1661 0.7023 0.7023
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.023 0.0906 0.2213
Brugia malayi histone deacetylase 1 (HD1) 0.0089 0.0305 0.0305
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0534 0.2208 0.2204
Loa Loa (eye worm) cathepsin B 0.089 0.373 0.373
Brugia malayi Papain family cysteine protease containing protein 0.0234 0.0922 0.0922
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0086 0.0289 0.0425
Entamoeba histolytica cysteine proteinase, putative 0.0534 0.2208 0.5388
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0015 0.0015
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0234 0.0922 0.0922
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0035 0.0073 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0015
Leishmania major phospholipase c-like protein 0.0098 0.0343 0.0505
Echinococcus granulosus cathepsin L cysteine proteinase 0.0976 0.4094 0.4094
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0086 0.0289 0.0764
Entamoeba histolytica prolyl oligopeptidase family protein 0.023 0.0906 0.2204
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0121 0.0285
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0099 0.0099
Schistosoma mansoni cathepsin s 0.0301 0.121 0.121
Onchocerca volvulus 0.0498 0.2051 0.3056
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0234 0.0922 0.2244
Entamoeba histolytica cysteine proteinase 2 0.0534 0.2208 0.5388
Brugia malayi Cathepsin L-like precursor 0.0976 0.4094 0.4094
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0568 0.2351 0.2348
Echinococcus granulosus glycoprotein Antigen 5 0.0035 0.0073 0.0073
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.2598
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0099 0.0099
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0015
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0092 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.2357 1 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0073 0.0073
Leishmania major hypothetical protein, conserved 0.0098 0.0343 0.0505
Brugia malayi Papain family cysteine protease containing protein 0.0534 0.2208 0.2208
Mycobacterium tuberculosis Long conserved protein 0.0544 0.2248 0.3917
Brugia malayi nuclear hormone receptor 0.0021 0.0015 0.0015
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0099 0.0099
Schistosoma mansoni reticulocalbin 0.01 0.035 0.035
Schistosoma mansoni microtubule-associated protein tau 0.1473 0.6219 0.6219
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0568 0.2351 0.2348
Schistosoma mansoni hypothetical protein 0.0035 0.0073 0.0073
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0194 0.0194
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0144 0.0351
Leishmania major calpain family cysteine protease-like protein 0.0188 0.0729 0.108
Brugia malayi beta-lactamase family protein 0.0036 0.0076 0.0076
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0099 0.0099
Brugia malayi proteasome subunit beta type 2 0.0041 0.01 0.01
Brugia malayi Cathepsin L-like precursor 0.0675 0.2808 0.2808
Echinococcus granulosus cathepsin L 0.0234 0.0922 0.0922
Loa Loa (eye worm) hypothetical protein 0.0042 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0099
Leishmania major cathepsin L-like protease 0.0976 0.4094 0.6096
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0234 0.0922 0.2463
Echinococcus multilocularis transmembrane protease serine 3 0.0035 0.0073 0.0073
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0188 0.0729 0.0725
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.023 0.0906 0.135
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0121 0.0203
Loa Loa (eye worm) histone deacetylase 1 0.0089 0.0305 0.0305
Entamoeba histolytica hypothetical protein, conserved 0.01 0.035 0.0845
Loa Loa (eye worm) hypothetical protein 0.0043 0.0107 0.0107
Brugia malayi Histone deacetylase family protein 0.01 0.0352 0.0352
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0099 0.0099
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0015
Loa Loa (eye worm) histone deacetylase 11 0.0043 0.0107 0.0107
Giardia lamblia Proteasome subunit beta type 1 0.0066 0.0208 0.0545
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0066 0.0208 0.0497
Giardia lamblia Cysteine protease 0.0234 0.0922 0.2463
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0234 0.0922 0.2253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0105 0.0105
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0234 0.0922 0.0922
Entamoeba histolytica cysteine proteinase 1, putative 0.0534 0.2208 0.5388
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Brugia malayi Calmodulin-like protein 0.0098 0.0343 0.0343
Entamoeba histolytica cysteine protease, putative 0.0234 0.0922 0.2244
Mycobacterium ulcerans hypothetical protein 0.0035 0.0073 0.0245
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Leishmania major centrin, putative,caltractin, putative 0.0098 0.0343 0.0505
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0437 0.1792 0.1792
Onchocerca volvulus 0.0976 0.4094 0.6099
Entamoeba histolytica calmodulin, putative 0.0098 0.0343 0.0828
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.0922 0.2253
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0099 0.0099
Echinococcus granulosus EF hand domain containing family member A2 0.0098 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0234 0.0922 0.0922
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0099 0.0099
Trypanosoma brucei hypothetical protein 0.0188 0.0729 0.108
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0098 0.0343 0.0343
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0305 0.0744
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0068 0.0064
Echinococcus multilocularis inhibitor of apoptosis protein 0.0175 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0004
Entamoeba histolytica hypothetical protein, conserved 0.023 0.0906 0.2204
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0015
Echinococcus granulosus calpain 5 0.0627 0.2602 0.2602
Trypanosoma brucei calpain, putative 0.0188 0.0729 0.108
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0234 0.0922 0.0922
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0105 0.01
Echinococcus granulosus cathepsin L 0.0534 0.2208 0.2208
Schistosoma mansoni cathepsin C 0.0234 0.0922 0.0922
Brugia malayi calpain 5 0.0188 0.0729 0.0729
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0105 0.0256
Entamoeba histolytica calcium binding family protein 0.0098 0.0343 0.0828
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0099 0.0241
Trypanosoma brucei calpain-like protein, putative 0.0627 0.2602 0.3872
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0086 0.0289 0.0497
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0041 0.01 0.01
Trichomonas vaginalis glycogen phosphorylase, putative 0.0107 0.038 0.0929
Schistosoma mansoni gamma-secretase subunit aph-1 0.0243 0.096 0.096
Entamoeba histolytica hypothetical protein 0.0041 0.0099 0.023
Leishmania major i/6 autoantigen-like protein 0.0098 0.0343 0.0505
Onchocerca volvulus 0.0234 0.0922 0.1374
Echinococcus granulosus cysteine protease 0.0534 0.2208 0.2208
Trichomonas vaginalis conserved hypothetical protein 0.0234 0.0922 0.2253
Leishmania major cytochrome p450-like protein 0.0034 0.0068 0.0095
Mycobacterium leprae Conserved hypothetical protein 0.0544 0.2248 0.7956
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0066 0.0208 0.0208
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2357 1 1
Echinococcus granulosus neurocalcin 0.0098 0.0343 0.0343
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0076 0.0076
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Brugia malayi Cathepsin L-like precursor 0.0976 0.4094 0.4094
Leishmania major oligopeptidase b 0.0674 0.2805 0.4175
Toxoplasma gondii cathepsin B 0.089 0.373 0.5557
Trypanosoma brucei centrin, putative 0.0098 0.0343 0.0505
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0068 0.0064
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0092 0.0315 0.0315
Brugia malayi Trypsin family protein 0.0035 0.0073 0.0073
Brugia malayi Cathepsin L-like precursor 0.0976 0.4094 0.4094
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0188 0.0729 0.178
Brugia malayi cathepsin F-like cysteine proteinase 0.0234 0.0922 0.0922
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0234 0.0922 0.2253
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0066 0.0208 0.0508
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0127 0.0468 0.0809
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0099 0.0099
Trichomonas vaginalis myosin light chain 1, putative 0.0098 0.0343 0.0839
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0234 0.0922 0.2253
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0187
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0121 0.0285
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0015
Brugia malayi Trypsin family protein 0.0035 0.0073 0.0073
Trypanosoma cruzi I/6 autoantigen, putative 0.0098 0.0343 0.0339
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0015
Leishmania major centrin, putative 0.0098 0.0343 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0976 0.4094 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0015
Echinococcus granulosus Transglutaminase 0.0544 0.2248 0.2248
Leishmania major histone deacetylase, putative 0.01 0.0352 0.0517
Loa Loa (eye worm) hypothetical protein 0.1661 0.7023 0.7023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0234 0.0922 0.2253
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Giardia lamblia Hypothetical protein 0.0234 0.0922 0.2463
Giardia lamblia Cathepsin B precursor 0.0234 0.0922 0.2463
Trypanosoma brucei calpain, putative 0.0188 0.0729 0.108
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Echinococcus granulosus cathepsin b 0.2357 1 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0076 0.0256
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0144 0.0351
Entamoeba histolytica cysteine proteinase, putative 0.0534 0.2208 0.5388
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Plasmodium falciparum serine repeat antigen 7 0.0234 0.0922 0.2253
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0534 0.2208 0.2208
Brugia malayi cathepsin L-like cysteine proteinase 0.0234 0.0922 0.0922
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.023 0.0906 0.0906
Brugia malayi calpain 7 0.0627 0.2602 0.2602
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0098 0.0343 0.0339
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0098 0.0343 0.0839
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0086 0.0289 0.0707
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0234 0.0922 0.2253
Toxoplasma gondii histone deacetylase HDAC2 0.0089 0.0305 0.0454
Echinococcus granulosus cathepsin l1 0.0976 0.4094 0.4094
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0188 0.0729 0.178
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0234 0.0922 0.2463
Mycobacterium tuberculosis Hypothetical protein 0.0544 0.2248 0.3917
Echinococcus granulosus transmembrane protease serine 3 0.0035 0.0073 0.0073
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0534 0.2208 0.5394
Plasmodium vivax histone deacetylase 2, putative 0.01 0.0352 0.0859
Loa Loa (eye worm) hypothetical protein 0.0052 0.0147 0.0147
Plasmodium falciparum serine repeat antigen 1 0.0234 0.0922 0.2253
Brugia malayi cathepsin Z-like cysteine proteinase 0.0234 0.0922 0.0922
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0015 0.0015
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0066 0.0208 0.0303
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0098 0.0343 0.0828
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0319 0.0319
Brugia malayi prolyl oligopeptidase family protein 0.1588 0.6712 0.6712
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0234 0.0922 0.2253
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0041 0.01 0.0233
Schistosoma mansoni histone deacetylase hda2 0.0106 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0098 0.0343 0.0343
Leishmania major cysteine peptidase A (CPA) 0.0976 0.4094 0.6096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2357 1 1
Giardia lamblia Cathepsin L-like protease 0.0234 0.0922 0.2463
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0319 0.0319
Trypanosoma cruzi cysteine peptidase, putative 0.0534 0.2208 0.2204
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.0305 0.03
Echinococcus multilocularis calpain 7 (C02 family) 0.0627 0.2602 0.2602
Trichomonas vaginalis calcium binding proteins, putative 0.0098 0.0343 0.0839
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0362 0.1473 0.1469
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0015 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Entamoeba histolytica glycogen phosphorylase, putative 0.0107 0.038 0.0918
Toxoplasma gondii centrin 0.0098 0.0343 0.0512
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0015 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0305 0.0744
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Onchocerca volvulus 0.0976 0.4094 0.6099
Brugia malayi Papain family cysteine protease containing protein 0.0976 0.4094 0.4094
Loa Loa (eye worm) hypothetical protein 0.0234 0.0922 0.0922
Mycobacterium tuberculosis Conserved hypothetical protein 0.0544 0.2248 0.3917
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0066 0.0208 0.031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.3872
Echinococcus granulosus programmed cell death protein 0.0098 0.0343 0.0343
Leishmania major cathepsin L-like protease 0.0976 0.4094 0.6096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0234 0.0922 0.0922
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Echinococcus granulosus Glycosyl transferase family 35 0.0107 0.038 0.038
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0015 0.0015
Brugia malayi calpain 5 0.0438 0.1797 0.1797
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0076 0.0072
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Trypanosoma brucei prolyl oligopeptidase, putative 0.0674 0.2805 0.4175
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0234 0.0922 0.0922
Brugia malayi cathepsin L-like precursor 0.0675 0.2808 0.2808
Schistosoma mansoni hypothetical protein 0.0169 0.0646 0.0646
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0015 0.0015
Trypanosoma brucei histone deacetylase 2 0.0043 0.0107 0.0153
Schistosoma mansoni reticulocalbin 0.0098 0.0343 0.0343
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0015 0.0015
Mycobacterium ulcerans lipase LipD 0.0036 0.0076 0.0256
Loa Loa (eye worm) proteasome subunit beta type 2 0.0041 0.01 0.01
Echinococcus multilocularis survival motor neuron protein 1 0.0246 0.0977 0.0977
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0234 0.0922 0.2253
Loa Loa (eye worm) hypothetical protein 0.0339 0.1373 0.1373
Giardia lamblia Cathepsin B precursor 0.0234 0.0922 0.2463
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0041 0.01 0.0244
Brugia malayi prolyl oligopeptidase family protein 0.0568 0.2351 0.2351
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0105 0.01
Schistosoma mansoni glycogen phosphorylase 0.0107 0.038 0.038
Loa Loa (eye worm) histone deacetylase 3 0.0089 0.0305 0.0305
Brugia malayi hypothetical protein 0.0092 0.0315 0.0315
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.3872
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0041 0.01 0.01
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0076 0.0125
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2357 1 1
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0352 0.0347
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0147 0.0147
Trypanosoma brucei calmodulin, putative 0.01 0.035 0.0515
Echinococcus multilocularis tumor protein p63 0.0356 0.1448 0.1448
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0234 0.0922 0.0922
Onchocerca volvulus 0.0029 0.0047 0.007
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0068 0.0068
Plasmodium falciparum histone deacetylase 1 0.0089 0.0305 0.0744
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0076
Echinococcus granulosus centrin 2 0.0098 0.0343 0.0343
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0234 0.0922 0.2253
Onchocerca volvulus 0.1034 0.4345 0.6473
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0305 0.0744
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0627 0.2602 0.2598
Trypanosoma brucei centrin, putative 0.0098 0.0343 0.0505
Loa Loa (eye worm) hypothetical protein 0.0035 0.0073 0.0073
Leishmania major calmodulin, putative 0.0098 0.0343 0.0505
Trypanosoma brucei histone deacetylase 4 0.01 0.0352 0.0517
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0301 0.121 0.121
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0125 0.0306
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Onchocerca volvulus 0.0098 0.0343 0.0512
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Schistosoma mansoni coup transcription factor 0.0021 0.0015 0.0015
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0627 0.2602 0.2598
Onchocerca volvulus Cathepsin F homolog 0.0976 0.4094 0.6099
Giardia lamblia Cathepsin L-like protease 0.0234 0.0922 0.2463
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0015
Echinococcus granulosus calmodulin 0.0098 0.0343 0.0343
Schistosoma mansoni cathepsin S (C01 family) 0.0234 0.0922 0.0922
Brugia malayi histone deacetylase 3 (HD3) 0.0089 0.0305 0.0305
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0035 0.0073 0.0073
Loa Loa (eye worm) glycogen phosphorylase 0.0107 0.038 0.038
Echinococcus granulosus histone deacetylase 1 0.0089 0.0305 0.0305
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0105 0.0256
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.0922 0.2253
Entamoeba histolytica histone deacetylase, putative 0.0089 0.0305 0.0734
Giardia lamblia Cathepsin B precursor 0.089 0.373 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0076 0.0076
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0788 0.3292 0.3292
Onchocerca volvulus 0.0976 0.4094 0.6099
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0175 0.067 0.067
Schistosoma mansoni cpg binding protein 0.0031 0.0054 0.0054
Echinococcus multilocularis proteasome (prosome, macropain) 0.0086 0.0289 0.0289
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0775 0.3237 0.3234
Mycobacterium ulcerans proteasome PrcB 0.0086 0.0289 0.1017
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0188 0.0729 0.178
Giardia lamblia Proteasome subunit beta type 2 0.0041 0.01 0.0255
Leishmania major cathepsin L-like protease 0.1076 0.4523 0.6736
Echinococcus granulosus EF HAND 1 calcium binding site 0.0098 0.0343 0.0343
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0066 0.0208 0.0508
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0105 0.0245
Trichomonas vaginalis calpain, putative 0.0188 0.0729 0.178
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0098 0.0343 0.0839
Toxoplasma gondii cathepsin CPL 0.0976 0.4094 0.6099
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0788 0.3292 0.3292
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0301 0.121 0.121
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0098 0.0343 0.0343
Toxoplasma gondii histone deacetylase HDAC4 0.0043 0.0107 0.016
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0824 0.3445 0.3445
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Leishmania major cathepsin L-like protease 0.0976 0.4094 0.6096
Schistosoma mansoni histone deacetylase 1 2 3 0.0043 0.0107 0.0107
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0352 0.0352
Schistosoma mansoni calpain (C02 family) 0.0627 0.2602 0.2602
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0241
Trichomonas vaginalis calcineurin B subunit, putative 0.01 0.035 0.0856
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0234 0.0922 0.2253
Chlamydia trachomatis glycogen phosphorylase 0.0107 0.038 0.5
Trichomonas vaginalis hypothetical protein 0.0188 0.0729 0.178
Leishmania major calpain protease-like protein 0.0188 0.0729 0.108
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0144 0.0144
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0976 0.4094 0.4094
Schistosoma mansoni neuronal calcium sensor 0.0098 0.0343 0.0343
Loa Loa (eye worm) calpain family protein 1 0.1661 0.7023 0.7023
Trichomonas vaginalis calcium binding protein, putative 0.0098 0.0343 0.0839
Plasmodium vivax vivapain-2 0.0976 0.4094 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0073 0.0073
Onchocerca volvulus 0.0732 0.3054 0.455
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Brugia malayi hypothetical protein 0.0035 0.0073 0.0073
Echinococcus granulosus inhibitor of apoptosis protein 0.0175 0.067 0.067
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0098 0.0343 0.0505
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0005 0.5
Toxoplasma gondii kringle domain-containing protein 0.0024 0.0024 0.0036
Leishmania major calmodulin-like protein 0.0098 0.0343 0.0505
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0234 0.0922 0.0922
Brugia malayi ecdysteroid receptor 0.0021 0.0015 0.0015
Giardia lamblia Encystation-specific protease 0.0234 0.0922 0.2463
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0005 0.0005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0976 0.4094 1
Trypanosoma brucei centrin-3 0.0098 0.0343 0.0505
Trichomonas vaginalis centrin, putative 0.0098 0.0343 0.0839
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.0922 0.2253
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0319 0.0319
Giardia lamblia Glycogen phosphorylase 0.0107 0.038 0.1008
Echinococcus multilocularis tissue type plasminogen activator 0.0024 0.0024 0.0024
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0035 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0185 0.0716 0.0716
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Leishmania major centrin, putative 0.0098 0.0343 0.0505
Loa Loa (eye worm) calmodulin-like protein 0.0098 0.0343 0.0343
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0086 0.0289 0.0289
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0188 0.0729 0.0725
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0015 0.0015
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0105 0.0245
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0098 0.0343 0.0839
Echinococcus granulosus Dipeptidyl peptidase 9 0.0568 0.2351 0.2351
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0459 0.1884 0.2807
Schistosoma mansoni cathepsin B (C01 family) 0.0234 0.0922 0.0922
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0076 0.0125
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.089 0.373 0.3727
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Brugia malayi Cathepsin L-like cysteine proteinase 0.0675 0.2808 0.2808
Onchocerca volvulus 0.0098 0.0343 0.0512
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0127 0.0468 0.0468
Brugia malayi prolyl oligopeptidase family protein 0.023 0.0906 0.0906
Leishmania major proteasome beta 5 subunit, putative 0.0086 0.0289 0.0425
Brugia malayi Papain family cysteine protease containing protein 0.0534 0.2208 0.2208
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Onchocerca volvulus Cell death protein 3 homolog 0.0092 0.0315 0.047
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0175 0.0672 0.0672
Entamoeba histolytica cysteine protease, putative 0.0234 0.0922 0.2244
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0976 0.4094 0.4094
Trypanosoma cruzi cruzipain precursor, putative 0.0301 0.121 0.1205
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0099 0.0099
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.023 0.0906 0.2213
Brugia malayi Cytochrome P450 family protein 0.0034 0.0068 0.0068
Echinococcus granulosus tumor protein p63 0.0356 0.1448 0.1448
Loa Loa (eye worm) prolyl oligopeptidase 0.0824 0.3445 0.3445
Giardia lamblia Cathepsin L precursor 0.0234 0.0922 0.2463
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0015
Echinococcus multilocularis Transglutaminase 0.0544 0.2248 0.2248
Onchocerca volvulus 0.0036 0.0076 0.0114
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0674 0.2805 0.4175
Entamoeba histolytica cysteine protease, putative 0.0234 0.0922 0.2244
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0234 0.0922 0.2253
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0243 0.096 0.096
Onchocerca volvulus 0.0035 0.0073 0.0109
Loa Loa (eye worm) hypothetical protein 0.0057 0.0168 0.0168
Brugia malayi EF hand family protein 0.0098 0.0343 0.0343
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Trypanosoma cruzi cysteine protease, putative 0.0534 0.2208 0.2204
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0234 0.0922 0.0922
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0099
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0182 0.0182
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0234 0.0922 0.0922
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0305 0.0744
Onchocerca volvulus 0.0063 0.0194 0.0289
Brugia malayi prolyl oligopeptidase family protein 0.023 0.0906 0.0906
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.0922 0.2253
Trypanosoma cruzi oligopeptidase b 0.0674 0.2805 0.2802
Giardia lamblia Cathepsin B precursor 0.0234 0.0922 0.2463
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0076
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0098 0.0343 0.0343
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0305 0.0744
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0188 0.0729 0.0725
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0105 0.0156
Brugia malayi programmed cell death protein 6 0.0098 0.0343 0.0343
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0234 0.0922 0.2253
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Trypanosoma cruzi major cysteine proteinase, putative 0.0234 0.0922 0.0918
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0534 0.2208 0.2208
Loa Loa (eye worm) hypothetical protein 0.0042 0.0105 0.0105
Loa Loa (eye worm) ctsf protein 0.0976 0.4094 0.4094
Schistosoma mansoni cpg binding protein 0.0029 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0099
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0076 0.0125
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0824 0.3445 0.3445
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0188 0.0729 0.0725
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0188 0.0729 0.0725
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.0922 0.2253
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1759 0.7443 0.7443
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Loa Loa (eye worm) hypothetical protein 0.0301 0.121 0.121
Trypanosoma brucei Component of motile flagella 41 0.0098 0.0343 0.0505
Plasmodium vivax vivapain-2 0.0976 0.4094 1
Brugia malayi Pre-SET motif family protein 0.0063 0.0194 0.0194
Trypanosoma cruzi calmodulin, putative 0.0098 0.0343 0.0339
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.0466 0.0466
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.0005
Schistosoma mansoni rab 0.0098 0.0343 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0241
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0175 0.067 0.067
Onchocerca volvulus Prolyl endopeptidase homolog 0.1588 0.6712 1
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0099 0.0099
Echinococcus granulosus histone deacetylase 3 0.0089 0.0305 0.0305
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.01 0.0244
Echinococcus multilocularis calpain 5 0.0627 0.2602 0.2602
Trypanosoma brucei prolyl endopeptidase 0.1588 0.6712 1
Echinococcus granulosus glycogen phosphorylase 0.0107 0.038 0.038
Entamoeba histolytica protein kinase, putative 0.0438 0.1797 0.4382
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0076 0.0256
Brugia malayi Thioredoxin family protein 0.0544 0.2248 0.2248
Leishmania major hypothetical protein, unknown function 0.0188 0.0729 0.108
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0099
Plasmodium falciparum cysteine proteinase falcipain 3 0.0976 0.4094 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0194 0.0194
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Giardia lamblia Cathepsin B precursor 0.089 0.373 1
Onchocerca volvulus 0.0035 0.0073 0.0109
Trypanosoma cruzi kinesin, putative 0.0438 0.1797 0.1793
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0098 0.0343 0.0339
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0099 0.0099
Brugia malayi Protein kinase domain containing protein 0.0024 0.0024 0.0024
Echinococcus granulosus cathepsin b 0.2357 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Echinococcus multilocularis acylamino acid releasing enzyme 0.023 0.0906 0.0906
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0234 0.0922 0.2253
Schistosoma mansoni hypothetical protein 0.0092 0.0315 0.0315
Trypanosoma brucei kinesin, putative 0.0438 0.1797 0.2672
Giardia lamblia Cathepsin L precursor 0.0234 0.0922 0.2463
Loa Loa (eye worm) hypothetical protein 0.0089 0.0305 0.0305
Trichomonas vaginalis set domain proteins, putative 0.0497 0.205 0.5007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0534 0.2208 0.3285
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0005 0.0011
Brugia malayi Trypsin family protein 0.0035 0.0073 0.0073
Schistosoma mansoni calcium binding atopy-related autoantigen 0.01 0.035 0.035
Loa Loa (eye worm) EF hand family protein 0.0098 0.0343 0.0343
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0319 0.0319
Mycobacterium leprae Conserved hypothetical protein 0.0544 0.2248 0.7956
Trypanosoma brucei histone deacetylase 3 0.01 0.0352 0.0517
Brugia malayi acetyltransferase, GNAT family protein 0.0175 0.0672 0.0672
Schistosoma mansoni inhibitor of apoptosis protein 0.0175 0.067 0.067
Schistosoma mansoni calmodulin 0.0098 0.0343 0.0343
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0127 0.0468 0.0691
Plasmodium vivax vivapain-3 0.0534 0.2208 0.5394
Trichomonas vaginalis conserved hypothetical protein 0.0188 0.0729 0.178
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0144 0.0214
Echinococcus multilocularis histone deacetylase 6 0.01 0.0352 0.0352
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2357 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.023 0.0906 0.0902
Loa Loa (eye worm) hypothetical protein 0.0675 0.2808 0.2808
Onchocerca volvulus 0.0024 0.0024 0.0036
Echinococcus granulosus enteropeptidase 0.0035 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0035 0.0073 0.0073
Brugia malayi Proteasome A-type and B-type family protein 0.0086 0.0289 0.0289
Echinococcus multilocularis cysteine protease 0.0976 0.4094 0.4094
Plasmodium falciparum serine repeat antigen 2 0.0234 0.0922 0.2253
Entamoeba histolytica calpain family cysteine protease, putative 0.0188 0.0729 0.1771
Brugia malayi Cytochrome P450 family protein 0.0056 0.0162 0.0162
Brugia malayi cathepsin Z-like cysteine proteinase 0.0234 0.0922 0.0922
Onchocerca volvulus Cathepsin L homolog 0.0976 0.4094 0.6099
Brugia malayi histone deacetylase 11 0.0043 0.0107 0.0107
Brugia malayi steroid hormone receptor 0.0021 0.0015 0.0015
Mycobacterium tuberculosis Conserved hypothetical protein 0.0544 0.2248 0.3917
Echinococcus multilocularis caspase 2 0.0092 0.0315 0.0315
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Toxoplasma gondii histone deacetylase HDAC1 0.01 0.0352 0.0524
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.0922 0.2253
Brugia malayi hypothetical protein 0.0041 0.0099 0.0099
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0188 0.0729 0.108
Giardia lamblia Cathepsin L precursor 0.0234 0.0922 0.2463
Leishmania major proteasome beta 2 subunit, putative 0.0041 0.01 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.0922 0.2253
Leishmania major protein kinase, putative 0.0098 0.0343 0.0505
Echinococcus multilocularis EF hand domain containing family member A2 0.0098 0.0343 0.0343
Echinococcus granulosus calbindin 32 0.01 0.035 0.035
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0319 0.0319
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0568 0.2351 0.2351
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0674 0.2805 0.2802
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.3872
Echinococcus granulosus histone deacetylase 6 0.01 0.0352 0.0352
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Onchocerca volvulus 0.0159 0.0605 0.0902
Brugia malayi Cathepsin L-like precursor 0.0301 0.121 0.121
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0188 0.0729 0.178
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Toxoplasma gondii troponin c, isotype gamma, putative 0.0098 0.0343 0.0512
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0099 0.0099
Trypanosoma cruzi cysteine peptidase, putative 0.0976 0.4094 0.4091
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0234 0.0922 0.2253
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0234 0.0922 0.0922
Trypanosoma brucei cysteine peptidase C (CPC) 0.089 0.373 0.5554
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0162 0.0162
Schistosoma mansoni survival motor neuron protein 0.005 0.0139 0.0139
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0076 0.0125
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0468 0.1655
Loa Loa (eye worm) hypothetical protein 0.0675 0.2808 0.2808
Echinococcus multilocularis programmed cell death protein 0.0098 0.0343 0.0343
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0099 0.0099
Leishmania major hypothetical protein, conserved 0.0188 0.0729 0.108
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0127 0.0468 0.0468
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0234 0.0922 0.2253
Echinococcus granulosus histone deacetylase 6 0.01 0.0352 0.0352
Schistosoma mansoni cathepsin F (C01 family) 0.0976 0.4094 0.4094
Echinococcus granulosus tissue type plasminogen activator 0.0024 0.0024 0.0024
Leishmania major histone deacetylase, putative 0.01 0.0352 0.0517
Echinococcus granulosus cpg binding protein 0.0031 0.0054 0.0054
Entamoeba histolytica grainin 2 0.0098 0.0343 0.0828
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0105 0.0105
Echinococcus granulosus prolyl endopeptidase 0.1588 0.6712 0.6712
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Entamoeba histolytica cysteine protease, putative 0.0234 0.0922 0.2244
Trichomonas vaginalis esterase, putative 0.0036 0.0076 0.0187
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0976 0.4094 1
Entamoeba histolytica hypothetical protein 0.0041 0.0099 0.023
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0098 0.0343 0.0339
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0234 0.0922 0.2463
Echinococcus multilocularis apoptotic protease activating factor 1 0.0092 0.0315 0.0315
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Echinococcus multilocularis cathepsin L 0.0534 0.2208 0.2208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.0011
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0099 0.0099
Trichomonas vaginalis centrin, putative 0.0098 0.0343 0.0839
Plasmodium vivax hypothetical protein, conserved 0.023 0.0906 0.2213
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.01 0.01
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0175 0.067 0.067
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0105 0.0245
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0241
Schistosoma mansoni hypothetical protein 0.005 0.0139 0.0139
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0188 0.0729 0.0725
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Trypanosoma cruzi centrin, putative 0.0098 0.0343 0.0339
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0068 0.0227
Echinococcus multilocularis centrin 2 0.0098 0.0343 0.0343
Entamoeba histolytica cysteine proteinase, putative 0.0675 0.2808 0.6856
Loa Loa (eye worm) hypothetical protein 0.1223 0.515 0.515
Entamoeba histolytica cysteine protease, putative 0.0234 0.0922 0.2244
Schistosoma mansoni centrin-related 0.0098 0.0343 0.0343
Onchocerca volvulus 0.0976 0.4094 0.6099
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0076 0.0076
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0352 0.0352
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0187
Entamoeba histolytica cysteine proteinase, putative 0.0976 0.4094 1
Onchocerca volvulus 0.005 0.0139 0.0207
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Echinococcus granulosus Mastin 0.0035 0.0073 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0076 0.0072
Onchocerca volvulus 0.0675 0.2808 0.4183
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0076 0.0076
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0234 0.0922 0.2244
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Brugia malayi calpain D 0.0188 0.0729 0.0729
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0015
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0035 0.0073 0.0073
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0234 0.0922 0.0922
Loa Loa (eye worm) hypothetical protein 0.0042 0.0105 0.0105
Toxoplasma gondii EF hand domain-containing protein 0.0098 0.0343 0.0512
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0099
Onchocerca volvulus Histone deacetylase 10 homolog 0.0043 0.0107 0.016
Schistosoma mansoni cpg binding protein 0.0031 0.0054 0.0054
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0098 0.0343 0.0505
Brugia malayi calpain family protein 1 0.1661 0.7023 0.7023
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.089 0.373 0.5554
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0015 0.0015
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0098 0.0343 0.0339
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4094 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0627 0.2602 0.3872
Schistosoma mansoni calpain-7 (C02 family) 0.0629 0.2614 0.2614
Schistosoma mansoni hypothetical protein 0.0035 0.0073 0.0073
Giardia lamblia Alanyl dipeptidyl peptidase 0.023 0.0906 0.2419
Brugia malayi Papain family cysteine protease containing protein 0.0234 0.0922 0.0922
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Brugia malayi Kringle domain containing protein 0.0024 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0675 0.2808 0.2808
Echinococcus multilocularis calbindin 32 0.01 0.035 0.035
Trypanosoma cruzi cysteine peptidase, putative 0.1076 0.4523 0.4521
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0099 0.0099
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0035 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.1034 0.4345 0.4345
Schistosoma mansoni calpain-7 (C02 family) 0.0629 0.2614 0.2614
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0076
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.0466 0.0466
Echinococcus granulosus survival motor neuron protein 1 0.0246 0.0977 0.0977
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1076 0.4523 0.6736
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0005 0.5
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0073 0.0073
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.0725
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0121 0.0285
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.089 0.373 0.373
Brugia malayi Trypsin-like protease protein 5 0.0035 0.0073 0.0073
Echinococcus multilocularis glycogen phosphorylase 0.0107 0.038 0.038
Plasmodium falciparum serine repeat antigen 8 0.0234 0.0922 0.2253
Schistosoma mansoni calmodulin related calcium binding protein 0.0098 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.089 0.373 0.9111
Trypanosoma cruzi calmodulin, putative 0.0098 0.0343 0.0339
Plasmodium falciparum centrin-1 0.0098 0.0343 0.0839
Trichomonas vaginalis glycogen phosphorylase, putative 0.0107 0.038 0.0929
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0468 0.1655
Onchocerca volvulus 0.0976 0.4094 0.6099
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0105 0.0256
Trypanosoma cruzi cysteine peptidase, putative 0.1076 0.4523 0.4521
Echinococcus granulosus microtubule associated protein 2 0.1473 0.6219 0.6219
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0105 0.0269
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0041 0.01 0.0149
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0098 0.0343 0.0339
Onchocerca volvulus 0.01 0.035 0.0522
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0076
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.0005
Onchocerca volvulus 0.0175 0.067 0.0998
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0675 0.2808 0.6859
Echinococcus multilocularis Glycosyl transferase, family 35 0.0107 0.038 0.038
Plasmodium falciparum histone deacetylase 2 0.01 0.0352 0.0859
Schistosoma mansoni calmodulin 0.0098 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0234 0.0922 0.2253
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Echinococcus multilocularis histone deacetylase 0.01 0.0352 0.0352
Echinococcus granulosus EF hand domain containing family member A2 0.01 0.035 0.035
Echinococcus granulosus histone deacetylase 8 0.0043 0.0107 0.0107
Echinococcus granulosus calpain 7 C02 family 0.0627 0.2602 0.2602
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0208 0.0203
Echinococcus multilocularis calpain A 0.1761 0.745 0.745
Trypanosoma brucei Calpain-like protein 1.2 0.0188 0.0729 0.108
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0976 0.4094 1
Giardia lamblia Cathepsin B precursor 0.089 0.373 1
Echinococcus multilocularis histone deacetylase 1 0.0089 0.0305 0.0305
Trypanosoma cruzi oligopeptidase b 0.0674 0.2805 0.2802
Echinococcus multilocularis calmodulin 0.0098 0.0343 0.0343
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0109 0.0162
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0041 0.01 0.0142
Leishmania major calcineurin B subunit, putative 0.0098 0.0343 0.0505
Schistosoma mansoni neuronal calcium sensor 0.0098 0.0343 0.0343
Trypanosoma brucei histone deacetylase 1 0.0089 0.0305 0.0447
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0188 0.0729 0.1086
Onchocerca volvulus Glycogen phosphorylase homolog 0.0107 0.038 0.0566
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Trypanosoma brucei mitochondrial calcium uptake 1 0.0098 0.0343 0.0505
Loa Loa (eye worm) hypothetical protein 0.0362 0.1473 0.1473
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4094 1
Loa Loa (eye worm) hypothetical protein 0.023 0.0906 0.0906
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0105 0.0256
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0107 0.0103
Loa Loa (eye worm) hypothetical protein 0.1473 0.6218 0.6218
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0234 0.0922 0.2253
Giardia lamblia Histone deacetylase 0.0089 0.0305 0.0806
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0175 0.0672 0.0672
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0234 0.0922 0.2463
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0187
Echinococcus granulosus proteasome prosome macropain 0.0086 0.0289 0.0289
Brugia malayi Trypsin family protein 0.0035 0.0073 0.0073
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0073 0.0073
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.0305 0.0744
Echinococcus granulosus cathepsin l cysteine peptidase 0.0976 0.4094 0.4094
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1588 0.6712 0.6712
Leishmania major cathepsin L-like protease 0.1076 0.4523 0.6736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.0922 0.2253
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0086 0.0289 0.0696
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0015 0.0015
Echinococcus multilocularis cathepsin b 0.2357 1 1
Echinococcus multilocularis cysteine protease 0.0976 0.4094 0.4094
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Plasmodium falciparum calpain 0.0188 0.0729 0.178
Leishmania major calmodulin-like protein 0.0098 0.0343 0.0505
Echinococcus granulosus calpain A 0.0627 0.2602 0.2602
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0788 0.3292 0.3292
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0015 0.0015
Giardia lamblia Serine peptidase, putative 0.0042 0.0105 0.0269
Echinococcus multilocularis glycogen phosphorylase 0.0107 0.038 0.038
Plasmodium falciparum cysteine repeat modular protein 1 0.0024 0.0024 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0024 0.002
Plasmodium vivax SET domain protein, putative 0.0063 0.0194 0.0474
Trypanosoma brucei I/6 autoantigen 0.0098 0.0343 0.0505
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0105 0.0105
Mycobacterium tuberculosis Probable peptidase 0.0674 0.2805 0.4891
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0194 0.0194
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0568 0.2351 0.3498
Onchocerca volvulus 0.0976 0.4094 0.6099
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0015
Trypanosoma brucei C-8 sterol isomerase, putative 0.0362 0.1473 0.2189
Trypanosoma brucei hypothetical protein, conserved 0.0098 0.0343 0.0505
Giardia lamblia Cathepsin L precursor 0.0234 0.0922 0.2463
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0188 0.0729 0.0725
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0099 0.0099
Brugia malayi nuclear receptor NHR-88 0.0021 0.0015 0.0015
Echinococcus granulosus histone deacetylase 7 0.01 0.0352 0.0352
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0352 0.0347
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) histone deacetylase 7A 0.01 0.0352 0.0352
Entamoeba histolytica cysteine protease, putative 0.0534 0.2208 0.5388
Brugia malayi hypothetical protein 0.0041 0.0099 0.0099
Plasmodium vivax unspecified product 0.0534 0.2208 0.5394
Schistosoma mansoni Mername-AA248 (C02 family) 0.0627 0.2602 0.2602
Loa Loa (eye worm) calpain D 0.0188 0.0729 0.0729
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0674 0.2805 0.4891
Toxoplasma gondii exonuclease III APE 0.0019 0.0005 0.0007
Trypanosoma brucei calpain-like protein, putative 0.0627 0.2602 0.3872
Toxoplasma gondii histone deacetylase HDAC3 0.0089 0.0305 0.0454
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0651 0.0651
Plasmodium vivax serine-repeat antigen (SERA) 0.0234 0.0922 0.2253
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0086 0.0289 0.078
Toxoplasma gondii proteasome subunit beta type, putative 0.0086 0.0289 0.0431
Echinococcus granulosus histone deacetylase 6 0.0106 0.0378 0.0378
Trichomonas vaginalis calmodulin, putative 0.0098 0.0343 0.0839
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0241
Mycobacterium ulcerans putative transglutaminase-like protein 0.0544 0.2248 0.8009
Schistosoma mansoni neuronal calcium sensor 0.0098 0.0343 0.0343
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0627 0.2602 0.2598
Leishmania major histone deacetylase, putative 0.0089 0.0305 0.0447
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0121 0.0121
Trichomonas vaginalis calcium binding protein, putative 0.0098 0.0343 0.0839
Loa Loa (eye worm) beta-lactamase 0.0036 0.0076 0.0076
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0015 0.0015
Brugia malayi CXXC zinc finger family protein 0.0029 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0468 0.0468
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.023 0.0906 0.1344
Echinococcus multilocularis neuronal calcium sensor 0.0098 0.0343 0.0343
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0234 0.0922 0.0922
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0015 0.0015
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0099 0.0099
Leishmania major hypothetical protein, conserved 0.0024 0.0024 0.0029
Brugia malayi Cathepsin L-like precursor 0.0675 0.2808 0.2808
Trypanosoma cruzi centrin-3 0.0098 0.0343 0.0339
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0015 0.0022
Echinococcus multilocularis microtubule associated protein 2 0.1473 0.6219 0.6219
Plasmodium falciparum serine repeat antigen 3 0.0234 0.0922 0.2253
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0144 0.0351
Leishmania major cathepsin L-like protease 0.1076 0.4523 0.6736
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0188 0.0729 0.108
Brugia malayi fibroinase precursor 0.0234 0.0922 0.0922
Echinococcus granulosus calpain A 0.1761 0.745 0.745
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0627 0.2602 0.2598
Brugia malayi Papain family cysteine protease containing protein 0.0234 0.0922 0.0922
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0015
Toxoplasma gondii hypothetical protein 0.0188 0.0729 0.1086
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0015 0.0015
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0099 0.0099
Trypanosoma brucei Calpain-like protein CALP1.3 0.0188 0.0729 0.108
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.1588 0.6712 0.6712
Plasmodium falciparum proteasome subunit beta type-5 0.0086 0.0289 0.0707
Giardia lamblia Cathepsin L precursor 0.0234 0.0922 0.2463
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0099 0.0099
Echinococcus multilocularis cathepsin b 0.2357 1 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 39.8107 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.