Detailed information for compound 1411868

Basic information

Technical information
  • TDR Targets ID: 1411868
  • Name: N-[2-(2,3-dihydroindol-1-yl)-2-phenylethyl]be nzenesulfonamide
  • MW: 378.487 | Formula: C22H22N2O2S
  • H donors: 1 H acceptors: 2 LogP: 4.27 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=S(=O)(c1ccccc1)NCC(N1CCc2c1cccc2)c1ccccc1
  • InChi: 1S/C22H22N2O2S/c25-27(26,20-12-5-2-6-13-20)23-17-22(18-9-3-1-4-10-18)24-16-15-19-11-7-8-14-21(19)24/h1-14,22-23H,15-17H2
  • InChiKey: HJHPOQFCILAWHH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-indolin-1-yl-2-phenyl-ethyl)benzenesulfonamide
  • N-[2-(1-indolinyl)-2-phenylethyl]benzenesulfonamide
  • N-[2-(2,3-dihydroindol-1-yl)-2-phenyl-ethyl]benzenesulfonamide
  • D030-0213
  • NCGC00114784-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Echinococcus granulosus GPCR family 2 0.0019 0.0002 0.0002
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.17 0.5712 0.5712
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0083 0.0083
Onchocerca volvulus Peroxidase homolog 0.0064 0.0156 0.0273
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0305 0.0305
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0082 0.0082
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0299 0.0953 0.0953
Loa Loa (eye worm) hypothetical protein 0.0046 0.0092 0.0092
Onchocerca volvulus 0.0989 0.3297 0.5772
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.17 0.5712 1
Brugia malayi Kringle domain containing protein 0.0025 0.002 0.002
Echinococcus multilocularis EF hand domain containing family member A2 0.0136 0.0397 0.0397
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0104 0.0289 0.087
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.055 0.1806 0.1806
Schistosoma mansoni calmodulin 0.0136 0.0397 0.0397
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0156 0.0156
Echinococcus multilocularis calmodulin 0.0136 0.0397 0.0397
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0135 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0397 0.1092
Brugia malayi Trypsin family protein 0.0066 0.0161 0.0161
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0083 0.0141
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0247 0.0776 0.1356
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0043 0.0082 0.0241
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2381 0.8022 0.8022
Trypanosoma brucei centrin-3 0.0139 0.041 0.0714
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Trypanosoma cruzi cysteine peptidase, putative 0.1094 0.3652 0.3651
Echinococcus multilocularis expressed protein 0.083 0.2757 0.2757
Loa Loa (eye worm) hypothetical protein 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0012 0.0012
Echinococcus multilocularis Glycosyl transferase, family 35 0.0108 0.0305 0.0305
Echinococcus multilocularis hypothetical protein 0.0842 0.2795 0.2795
Toxoplasma gondii exonuclease III APE 0.0019 0.0002 0.0004
Brugia malayi Cytochrome P450 family protein 0.0058 0.0135 0.0135
Brugia malayi calpain family protein 1 0.2245 0.7562 0.7562
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Echinococcus granulosus histone deacetylase 6 0.0097 0.0267 0.0267
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0057 0.0055
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0083 0.0083
Echinococcus granulosus calcium uptake protein 1 0.0138 0.0405 0.0405
Brugia malayi cathepsin F-like cysteine proteinase 0.0251 0.0789 0.0789
Brugia malayi cathepsin Z-like cysteine proteinase 0.0251 0.0789 0.0789
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0158 0.0158
Plasmodium falciparum serine repeat antigen 6 0.0251 0.0789 0.2394
Echinococcus granulosus endothelin converting enzyme 1 0.0092 0.025 0.025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.055 0.1806 0.3159
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0083 0.0083
Onchocerca volvulus 0.0035 0.0057 0.01
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.055 0.1806 0.1806
Loa Loa (eye worm) hypothetical protein 0.0989 0.3297 0.3297
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0057 0.0057
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0136 0.0397 0.1199
Giardia lamblia Cathepsin B precursor 0.109 0.3638 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0089 0.0239 0.0237
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0251 0.0789 0.2169
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0043 0.0082 0.0225
Echinococcus multilocularis glycoprotein Antigen 5 0.0066 0.0161 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0327 0.1049 0.2882
Echinococcus multilocularis dnaJ subfamily B 0.0418 0.1356 0.1356
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0251 0.0789 0.0789
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Brugia malayi Cathepsin L-like precursor 0.0989 0.3297 0.3297
Brugia malayi proteasome subunit beta type 1 0.0069 0.0172 0.0172
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0012 0.0012
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Trypanosoma brucei Calpain-like protein 1.1 0.0247 0.0776 0.1356
Brugia malayi Cathepsin L-like precursor 0.069 0.228 0.228
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0251 0.0789 0.2394
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0355 0.0355
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0066 0.0161 0.0161
Brugia malayi fibroinase precursor 0.0251 0.0789 0.0789
Plasmodium falciparum cysteine proteinase falcipain 1 0.055 0.1806 0.5478
Trypanosoma cruzi cysteine protease, putative 0.055 0.1806 0.1804
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0104 0.0289 0.0794
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0251 0.0789 0.0789
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0012 0.0012
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Brugia malayi Peroxidasin 0.0064 0.0156 0.0156
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0057 0.0157
Leishmania major cathepsin L-like protease 0.0989 0.3297 0.577
Loa Loa (eye worm) hypothetical protein 0.0055 0.0125 0.0125
Trypanosoma brucei C-8 sterol isomerase, putative 0.0359 0.1155 0.202
Echinococcus multilocularis inhibitor of apoptosis protein 0.0186 0.057 0.057
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0057 0.0054
Leishmania major cathepsin L-like protease 0.1094 0.3652 0.6392
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0247 0.0776 0.0774
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.0082 0.0082
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0012 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0012 0.0012
Giardia lamblia Cysteine protease 0.0251 0.0789 0.2165
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.027 0.027
Plasmodium vivax vivapain-2 0.0989 0.3297 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0043 0.0082 0.0082
Plasmodium vivax SET domain protein, putative 0.0065 0.0158 0.0479
Trypanosoma cruzi hypothetical protein, conserved 0.0327 0.1049 0.1047
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0842 0.2795 0.4892
Entamoeba histolytica histone deacetylase, putative 0.0086 0.023 0.0693
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0083 0.0227
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0096 0.0285
Giardia lamblia Cathepsin B precursor 0.0251 0.0789 0.2165
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Leishmania major calcineurin B subunit, putative 0.0136 0.0397 0.0692
Plasmodium falciparum histone deacetylase 1 0.0086 0.023 0.0699
Giardia lamblia Hypothetical protein 0.0138 0.0405 0.1109
Echinococcus granulosus cathepsin L cysteine proteinase 0.0989 0.3297 0.3297
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0251 0.0789 0.2169
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Loa Loa (eye worm) hypothetical protein 0.0066 0.0161 0.0161
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0136 0.0397 0.1199
Trypanosoma cruzi cysteine proteinase, putative 0.055 0.1806 0.1804
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0299 0.0953 0.0953
Loa Loa (eye worm) hypothetical protein 0.0066 0.0161 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Trypanosoma brucei calmodulin, putative 0.0138 0.0405 0.0706
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0136 0.0397 0.0692
Brugia malayi calpain 7 0.0842 0.2795 0.2795
Schistosoma mansoni cpg binding protein 0.0029 0.0037 0.0037
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0776 0.2574 1
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0057 0.012
Echinococcus multilocularis gamma secretase subunit aph 1 0.0252 0.0792 0.0792
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0168 0.0168
Echinococcus granulosus cathepsin l cysteine peptidase 0.0989 0.3297 0.3297
Echinococcus granulosus inhibitor of apoptosis protein 0.0186 0.057 0.057
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0174
Brugia malayi Blistered cuticle protein 3 0.0064 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0043 0.0082 0.0082
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0082 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0012 0.0012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0012 0.0012
Toxoplasma gondii EFHC1, putative 0.0136 0.0397 0.0696
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0252 0.0252
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0382 0.0382
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0002 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0382 0.1477
Loa Loa (eye worm) hypothetical protein 0.0104 0.0289 0.0289
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0012 0.0012
Brugia malayi Cathepsin L-like precursor 0.0989 0.3297 0.3297
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0327 0.1049 0.1049
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0012 0.0012
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.157 0.5268 0.9223
Entamoeba histolytica cysteine proteinase, putative 0.0989 0.3297 1
Trypanosoma cruzi centrin, putative 0.0139 0.041 0.0408
Echinococcus multilocularis apoptotic protease activating factor 1 0.0098 0.027 0.027
Plasmodium vivax vivapain-3 0.055 0.1806 0.5478
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0096 0.0285
Echinococcus multilocularis cathepsin L cysteine protease 0.0989 0.3297 0.3297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0251 0.0789 0.2169
Schistosoma mansoni cathepsin F (C01 family) 0.0989 0.3297 0.3297
Schistosoma mansoni memapsin-2 (A01 family) 0.0462 0.1507 0.1507
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Echinococcus granulosus proteasome prosome macropain 0.0089 0.0239 0.0239
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0141 0.0141
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0251 0.0789 0.2394
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Loa Loa (eye worm) calpain D 0.0247 0.0776 0.0776
Entamoeba histolytica cysteine proteinase, putative 0.055 0.1806 0.5475
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0305 0.0305
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0776 0.2574 0.2572
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.0079 0.0139
Entamoeba histolytica cysteine proteinase, putative 0.055 0.1806 0.5475
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.0789 0.2169
Trypanosoma cruzi kinesin, putative 0.0594 0.1956 0.1954
Trypanosoma brucei histone deacetylase 1 0.0086 0.023 0.04
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2963 1 1
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0305 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0776 0.2134
Onchocerca volvulus 0.0046 0.0092 0.0161
Trypanosoma cruzi cruzipain precursor, putative 0.1094 0.3652 0.3651
Echinococcus multilocularis calbindin 32 0.0138 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0299 0.0953 0.0953
Trichomonas vaginalis calcium binding proteins, putative 0.0136 0.0397 0.1092
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Onchocerca volvulus 0.0098 0.027 0.0472
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0082 0.0082
Leishmania major cathepsin L-like protease 0.1094 0.3652 0.6392
Giardia lamblia Hypothetical protein 0.0215 0.0666 0.1825
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.2794
Echinococcus granulosus EF hand domain containing family member A2 0.0136 0.0397 0.0397
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0078 0.0137
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.023 0.0633
Echinococcus multilocularis programmed cell death protein 0.0139 0.041 0.041
Onchocerca volvulus 0.0066 0.0161 0.0282
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0251 0.0789 0.2169
Plasmodium falciparum serine repeat antigen 4 0.0251 0.0789 0.2394
Brugia malayi cathepsin Z-like cysteine proteinase 0.0251 0.0789 0.0789
Trypanosoma cruzi histone deacetylase 1, putative 0.0086 0.023 0.0228
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0082 0.0082
Trichomonas vaginalis calcineurin B subunit, putative 0.0136 0.0397 0.1092
Schistosoma mansoni hypothetical protein 0.0024 0.0019 0.0019
Brugia malayi PXA domain containing protein 0.0043 0.0082 0.0082
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0172 0.0301
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0057 0.0157
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0012 0.0012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0007
Entamoeba histolytica calpain large subunit domain III containing protein 0.0594 0.1956 0.5931
Leishmania major phospholipase c-like protein 0.0136 0.0397 0.0692
Loa Loa (eye worm) hypothetical protein 0.2245 0.7562 0.7562
Brugia malayi beta-lactamase family protein 0.0035 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0251 0.0789 0.2169
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0136 0.0397 0.1092
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0012 0.0012
Brugia malayi Cathepsin L-like precursor 0.0989 0.3297 0.3297
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0043 0.0082 0.0082
Plasmodium falciparum cysteine repeat modular protein 1 0.0025 0.002 0.0061
Mycobacterium ulcerans hypothetical protein 0.0215 0.0666 0.2579
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Schistosoma mansoni neprilysin 0.0024 0.0019 0.0019
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0247 0.0776 0.0774
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0251 0.0789 0.2389
Entamoeba histolytica cysteine protease, putative 0.0251 0.0789 0.2389
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.0809 0.0809
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Plasmodium falciparum serine repeat antigen 1 0.0251 0.0789 0.2394
Mycobacterium tuberculosis Probable peptidase 0.0776 0.2574 0.5593
Plasmodium falciparum calpain 0.0247 0.0776 0.2355
Brugia malayi calpain D 0.0247 0.0776 0.0776
Echinococcus granulosus cathepsin b 0.2963 1 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0174
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0083 0.0145
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Echinococcus multilocularis regulator of G protein signaling 0.0043 0.0082 0.0082
Mycobacterium ulcerans hypothetical protein 0.0035 0.0057 0.0214
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0082 0.0082
Brugia malayi beta-lactamase 0.0035 0.0057 0.0057
Trypanosoma brucei histone deacetylase 4 0.0097 0.0267 0.0463
Loa Loa (eye worm) hypothetical protein 0.2963 1 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0043 0.0082 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0012 0.0012
Trichomonas vaginalis calmodulin, putative 0.0136 0.0397 0.1092
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.228 0.6268
Loa Loa (eye worm) hypothetical protein 0.0043 0.0082 0.0082
Echinococcus multilocularis calpain 0.0842 0.2795 0.2795
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0156 0.0156
Echinococcus granulosus histone deacetylase 3 0.0086 0.023 0.023
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0247 0.0776 0.0774
Echinococcus multilocularis histone deacetylase 3 0.0086 0.023 0.023
Onchocerca volvulus 0.0022 0.0012 0.002
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0095 0.0095
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0156 0.0156
Brugia malayi Papain family cysteine protease containing protein 0.055 0.1806 0.1806
Echinococcus granulosus cathepsin L cysteine protease 0.055 0.1806 0.1806
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0057 0.0057
Schistosoma mansoni peroxidasin 0.0064 0.0156 0.0156
Trypanosoma cruzi calmodulin, putative 0.0136 0.0397 0.0395
Echinococcus granulosus prolyl endopeptidase 0.17 0.5712 0.5712
Entamoeba histolytica cysteine proteinase, putative 0.069 0.228 0.6914
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0082 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Giardia lamblia Cathepsin L precursor 0.0251 0.0789 0.2165
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Onchocerca volvulus 0.0989 0.3297 0.5772
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0066 0.0161 0.0161
Onchocerca volvulus 0.0064 0.0156 0.0273
Toxoplasma gondii troponin c, isotype gamma, putative 0.0136 0.0397 0.0696
Brugia malayi Trypsin family protein 0.0066 0.0161 0.0161
Leishmania major hypothetical protein, conserved 0.0136 0.0397 0.0692
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0012 0.0012
Onchocerca volvulus 0.0035 0.0057 0.01
Loa Loa (eye worm) hypothetical protein 0.0061 0.0146 0.0146
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0247 0.0776 0.2134
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0172 0.0172
Echinococcus multilocularis cathepsin L 0.0251 0.0789 0.0789
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0092 0.025 0.025
Giardia lamblia Cathepsin B precursor 0.0251 0.0789 0.2165
Leishmania major histone deacetylase, putative 0.0086 0.023 0.04
Echinococcus multilocularis GPCR, family 2 0.0019 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0057 0.0057
Leishmania major cathepsin L-like protease 0.0989 0.3297 0.577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0251 0.0789 0.2169
Loa Loa (eye worm) hypothetical protein 0.0066 0.0161 0.0161
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0251 0.0789 0.2394
Loa Loa (eye worm) hypothetical protein 0.0068 0.0168 0.0168
Leishmania major histone deacetylase, putative 0.0086 0.023 0.04
Schistosoma mansoni cathepsin S (C01 family) 0.0251 0.0789 0.0789
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0082 0.0082
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0082 0.0082
Entamoeba histolytica cysteine proteinase, putative 0.055 0.1806 0.5475
Entamoeba histolytica calcium-binding protein, putative 0.0136 0.0397 0.1199
Brugia malayi prolyl oligopeptidase family protein 0.0327 0.1049 0.1049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Chlamydia trachomatis glycogen phosphorylase 0.0108 0.0305 0.5
Giardia lamblia Cathepsin L-like protease 0.0251 0.0789 0.2165
Brugia malayi hypothetical protein 0.0064 0.0156 0.0156
Echinococcus multilocularis cathepsin L 0.055 0.1806 0.1806
Plasmodium vivax vivapain-2 0.0989 0.3297 1
Echinococcus multilocularis neurocalcin 0.0136 0.0397 0.0397
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0252 0.0252
Plasmodium vivax histone deacetylase, putative 0.0042 0.0078 0.0238
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0305 0.0919
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0251 0.0789 0.2169
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0012 0.0012
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0156 0.0273
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0012 0.0012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Onchocerca volvulus 0.0215 0.0666 0.1165
Plasmodium vivax serine-repeat antigen (SERA) 0.0251 0.0789 0.2394
Brugia malayi Trypsin family protein 0.0066 0.0161 0.0161
Brugia malayi hypothetical protein 0.0166 0.0501 0.0501
Brugia malayi steroid hormone receptor 0.0022 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Brugia malayi Protein kinase domain containing protein 0.0025 0.002 0.002
Trypanosoma cruzi oligopeptidase b 0.0776 0.2574 0.2572
Onchocerca volvulus 0.0136 0.0397 0.0696
Toxoplasma gondii EF hand domain-containing protein 0.0136 0.0397 0.0696
Entamoeba histolytica hypothetical protein 0.0251 0.0789 0.2389
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0989 0.3297 1
Giardia lamblia Cathepsin L precursor 0.0251 0.0789 0.2165
Loa Loa (eye worm) hypothetical protein 0.0299 0.0953 0.0953
Schistosoma mansoni hypothetical protein 0.0136 0.0397 0.0397
Entamoeba histolytica cysteine protease, putative 0.0989 0.3297 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Loa Loa (eye worm) calpain family protein 1 0.1651 0.5543 0.5543
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0158 0.0158
Mycobacterium ulcerans putative transglutaminase-like protein 0.0215 0.0666 0.2579
Schistosoma mansoni hypothetical protein 0.0066 0.0161 0.0161
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0037 0.0037
Brugia malayi hypothetical protein 0.0043 0.0082 0.0082
Brugia malayi cathepsin L-like cysteine proteinase 0.0251 0.0789 0.0789
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0012 0.0012
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0083 0.0141
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0867 0.2881 0.5044
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.0809 0.0809
Schistosoma mansoni hypothetical protein 0.0024 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0251 0.0789 0.2169
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Loa Loa (eye worm) hypothetical protein 0.0042 0.0078 0.0078
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.1928 0.6485 0.6485
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0808 0.268 0.268
Echinococcus granulosus calpain A 0.0842 0.2795 0.2795
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2381 0.8022 0.8022
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0776 0.2574 0.4504
Giardia lamblia Histone deacetylase 0.0086 0.023 0.0628
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0136 0.0397 0.0395
Plasmodium vivax histone deacetylase 1, putative 0.0086 0.023 0.0699
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0012 0.0012
Trypanosoma brucei Aph-1 protein, putative 0.0098 0.027 0.0469
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Schistosoma mansoni neuronal calcium sensor 0.0136 0.0397 0.0397
Brugia malayi hypothetical protein 0.0066 0.0161 0.0161
Schistosoma mansoni cathepsin F (C01 family) 0.069 0.228 0.228
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0359 0.1155 0.1153
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0842 0.2795 0.2794
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0251 0.0789 0.0789
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0002 0.5
Loa Loa (eye worm) hypothetical protein 0.0092 0.025 0.025
Mycobacterium tuberculosis Hypothetical protein 0.0215 0.0666 0.1443
Schistosoma mansoni cathepsin C 0.0251 0.0789 0.0789
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0382 0.0826
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0158 0.0158
Brugia malayi prolyl oligopeptidase family protein 0.157 0.5268 0.5268
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.157 0.5268 0.5268
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0046 0.0095 0.0095
Schistosoma mansoni histone deacetylase 4 5 0.0097 0.0267 0.0267
Toxoplasma gondii histone deacetylase HDAC2 0.0086 0.023 0.0403
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0086 0.023 0.0633
Leishmania major centrin, putative 0.0136 0.0397 0.0692
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0172 0.0467
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0776 0.2574 0.4504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Plasmodium vivax unspecified product 0.0299 0.0953 0.2892
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0082 0.0225
Loa Loa (eye worm) calpain 0.0842 0.2795 0.2795
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0104 0.0289 0.0289
Trypanosoma brucei Calpain-like protein 1.2 0.0247 0.0776 0.1356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Trypanosoma brucei histone deacetylase 2 0.0042 0.0078 0.0134
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0251 0.0789 0.2165
Giardia lamblia Cysteine protease 0.0251 0.0789 0.2165
Loa Loa (eye worm) hypothetical protein 0.054 0.1769 0.1769
Schistosoma mansoni peroxidasin 0.0064 0.0156 0.0156
Mycobacterium ulcerans hypothetical protein 0.0215 0.0666 0.2579
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0251 0.0789 0.2169
Schistosoma mansoni hypothetical protein 0.0024 0.0019 0.0019
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0251 0.0789 0.2169
Brugia malayi cathepsin F-like cysteine proteinase 0.0299 0.0953 0.0953
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0083 0.0083
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0082 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0327 0.1049 0.1047
Entamoeba histolytica protein kinase, putative 0.0594 0.1956 0.5931
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0327 0.1049 0.1836
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0078 0.0076
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0012 0.0012
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0299 0.0953 0.0951
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Loa Loa (eye worm) calpain 5 0.0594 0.1956 0.1956
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0057 0.0057
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0989 0.3297 0.3297
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0136 0.0397 0.1205
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.109 0.3638 0.3637
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0327 0.1049 0.1833
Brugia malayi histone deacetylase 3 (HD3) 0.0086 0.023 0.023
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0115 0.0115
Leishmania major centrin, putative 0.0136 0.0397 0.0692
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0842 0.2795 0.2794
Leishmania major hypothetical protein, conserved 0.0138 0.0405 0.0706
Leishmania major cytochrome p450-like protein 0.0035 0.0057 0.0095
Loa Loa (eye worm) hypothetical protein 0.0257 0.0809 0.0809
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.157 0.5268 0.5268
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.1928 0.6485 0.6485
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.023 0.0633
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.069 0.228 0.228
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0092 0.025 0.0539
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Schistosoma mansoni reticulocalbin 0.0136 0.0397 0.0397
Echinococcus multilocularis tissue type plasminogen activator 0.0025 0.002 0.002
Echinococcus granulosus programmed cell death protein 0.0139 0.041 0.041
Brugia malayi Trypsin-like protease protein 5 0.0066 0.0161 0.0161
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0136 0.0397 0.0395
Loa Loa (eye worm) hypothetical protein 0.0092 0.025 0.025
Mycobacterium ulcerans proteasome PrcB 0.0089 0.0239 0.0923
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0247 0.0776 0.2134
Echinococcus granulosus histone deacetylase 8 0.0042 0.0078 0.0078
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0057 0.0057
Toxoplasma gondii peptidase family M13 protein 0.0092 0.025 0.0438
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0096 0.0285
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0305 0.0305
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0082 0.0082
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2245 0.7562 0.7562
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0083 0.0244
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0104 0.0289 0.0289
Echinococcus granulosus peroxidasin 0.0064 0.0156 0.0156
Leishmania major calpain family cysteine protease-like protein 0.0247 0.0776 0.1356
Schistosoma mansoni calpain-7 (C02 family) 0.0845 0.2806 0.2806
Onchocerca volvulus 0.0064 0.0156 0.0273
Echinococcus granulosus acylamino acid releasing enzyme 0.0327 0.1049 0.1049
Schistosoma mansoni neprilysin-2 (M13 family) 0.0046 0.0095 0.0095
Trypanosoma cruzi histone deacetylase 1, putative 0.0086 0.023 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0251 0.0789 0.2169
Onchocerca volvulus 0.0066 0.0161 0.0282
Loa Loa (eye worm) hypothetical protein 0.0035 0.0057 0.0057
Loa Loa (eye worm) fibroinase 0.0989 0.3297 0.3297
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0012 0.0012
Leishmania major histone deacetylase, putative 0.0097 0.0267 0.0463
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Onchocerca volvulus Cell death protein 3 homolog 0.0098 0.027 0.0472
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0095 0.0095
Trypanosoma cruzi centrin, putative 0.0139 0.041 0.0408
Toxoplasma gondii kringle domain-containing protein 0.0025 0.002 0.0035
Giardia lamblia Glycogen phosphorylase 0.0108 0.0305 0.0833
Toxoplasma gondii cathepsin CPC2 0.0251 0.0789 0.1382
Toxoplasma gondii centrin 0.0136 0.0397 0.0696
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0057 0.012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.055 0.1806 0.1806
Leishmania major programmed cell death 6 protein-like protein 0.0136 0.0397 0.0692
Echinococcus multilocularis histone deacetylase 6 0.0103 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0041 0.0077 0.0077
Leishmania major calmodulin-like protein 0.0136 0.0397 0.0692
Brugia malayi Calmodulin-like protein 0.0136 0.0397 0.0397
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0104 0.0289 0.0289
Echinococcus granulosus calumenin 0.0138 0.0405 0.0405
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0013 0.0013
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0138 0.0405 0.0403
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0136 0.0397 0.0397
Leishmania major hypothetical protein, conserved 0.0025 0.002 0.0031
Giardia lamblia Cathepsin B precursor 0.109 0.3638 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.2794
Entamoeba histolytica cysteine proteinase 2 0.055 0.1806 0.5475
Brugia malayi Thioredoxin family protein 0.0215 0.0666 0.0666
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0078 0.0076
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0776 0.2574 0.2572
Loa Loa (eye worm) hypothetical protein 0.0035 0.0057 0.0057
Trichomonas vaginalis calmodulin, putative 0.0139 0.041 0.1126
Leishmania major i/6 autoantigen-like protein 0.0136 0.0397 0.0692
Trichomonas vaginalis calcium binding protein, putative 0.0136 0.0397 0.1092
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0252 0.0252
Giardia lamblia Alanyl dipeptidyl peptidase 0.0327 0.1049 0.2878
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0251 0.0789 0.2394
Loa Loa (eye worm) histone deacetylase 0.0097 0.0267 0.0267
Echinococcus granulosus glycoprotein Antigen 5 0.0066 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0327 0.1049 0.1049
Trichomonas vaginalis calcineurin B subunit, putative 0.0138 0.0405 0.1115
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.0705 0.1529
Brugia malayi calcium-binding protein 0.0136 0.0397 0.0397
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.0082 0.0082
Plasmodium falciparum proteasome subunit beta type-5 0.0089 0.0239 0.0726
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0012 0.0012
Onchocerca volvulus Cathepsin L homolog 0.0251 0.0789 0.1382
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0776 0.2574 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.027 0.027
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0122 0.0122
Onchocerca volvulus Glycogen phosphorylase homolog 0.0108 0.0305 0.0534
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.027 0.0268
Brugia malayi calpain 5 0.0247 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.069 0.228 0.228
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Trypanosoma brucei prolyl endopeptidase 0.17 0.5712 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0012 0.0012
Brugia malayi Histone deacetylase 1 0.0086 0.023 0.023
Echinococcus multilocularis enteropeptidase 0.0066 0.0161 0.0161
Trichomonas vaginalis peptide N-glycanase, putative 0.0215 0.0666 0.1829
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Loa Loa (eye worm) hypothetical protein 0.1651 0.5543 0.5543
Brugia malayi A-kinase anchor protein 10, precursor 0.0043 0.0082 0.0082
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0186 0.057 0.057
Trypanosoma brucei histone deacetylase, putative 0.0097 0.0267 0.0463
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0138 0.0405 0.0405
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0359 0.1155 0.1155
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0172 0.0172
Brugia malayi gamma-secretase subunit aph-1 0.0252 0.0792 0.0792
Loa Loa (eye worm) hypothetical protein 0.0183 0.056 0.056
Plasmodium vivax histone deacetylase 2, putative 0.0097 0.0267 0.0809
Entamoeba histolytica prolyl oligopeptidase family protein 0.0327 0.1049 0.3176
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0247 0.0776 0.1356
Onchocerca volvulus 0.0512 0.1677 0.2936
Schistosoma mansoni calmodulin 0.0136 0.0397 0.0397
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.1201 0.4017 0.4017
Schistosoma mansoni neuronal calcium sensor 0.0136 0.0397 0.0397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0012 0.0012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.045 0.1465 0.1465
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.1201 0.4017 0.4015
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0089 0.0239 0.0653
Loa Loa (eye worm) histone deacetylase 1 0.0086 0.023 0.023
Trichomonas vaginalis calmodulin, putative 0.0136 0.0397 0.1092
Brugia malayi prolyl oligopeptidase family protein 0.0327 0.1049 0.1049
Onchocerca volvulus 0.0052 0.0115 0.0201
Onchocerca volvulus 0.0054 0.0122 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0012 0.0012
Brugia malayi Cathepsin L-like precursor 0.069 0.228 0.228
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0136 0.0397 0.0397
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2381 0.8022 0.8022
Mycobacterium ulcerans lipase LipD 0.0035 0.0057 0.0214
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0002 0.0002
Echinococcus multilocularis neuronal calcium sensor 0.0136 0.0397 0.0397
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0078 0.0078
Echinococcus multilocularis caspase 2 0.0098 0.027 0.027
Toxoplasma gondii ABC1 family protein 0.0035 0.0057 0.01
Mycobacterium tuberculosis Long conserved protein 0.0215 0.0666 0.1443
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Echinococcus multilocularis cathepsin L cysteine protease 0.0989 0.3297 0.3297
Schistosoma mansoni calpain C (C02 family) 0.0842 0.2795 0.2795
Trypanosoma brucei histone deacetylase 3 0.0097 0.0267 0.0463
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0247 0.0776 0.2134
Trypanosoma cruzi cysteine peptidase, putative 0.0989 0.3297 0.3295
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0066 0.0161 0.0161
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.006 0.0141 0.0141
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0082 0.0082
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Trypanosoma brucei hypothetical protein 0.0247 0.0776 0.1356
Schistosoma mansoni survival motor neuron protein 0.0052 0.0115 0.0115
Brugia malayi cathepsin L precursor 0.0251 0.0789 0.0789
Trypanosoma cruzi cruzipain precursor, putative 0.0299 0.0953 0.0951
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0012 0.0012
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0012 0.0012
Trypanosoma cruzi I/6 autoantigen, putative 0.0136 0.0397 0.0395
Trypanosoma cruzi calmodulin, putative 0.0136 0.0397 0.0395
Schistosoma mansoni microtubule-associated protein tau 0.1517 0.509 0.509
Leishmania major kinesin, putative 0.0594 0.1956 0.3422
Entamoeba histolytica calpain family cysteine protease, putative 0.0247 0.0776 0.235
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Loa Loa (eye worm) hypothetical protein 0.0136 0.0397 0.0397
Onchocerca volvulus 0.0186 0.057 0.0998
Trichomonas vaginalis calmodulin, putative 0.0136 0.0397 0.1092
Loa Loa (eye worm) hypothetical protein 0.0251 0.0789 0.0789
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Loa Loa (eye worm) prolyl oligopeptidase 0.157 0.5268 0.5268
Brugia malayi histone deacetylase 11 0.0042 0.0078 0.0078
Plasmodium vivax hypothetical protein, conserved 0.0327 0.1049 0.3181
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2963 1 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0057 0.0173
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0012 0.0012
Schistosoma mansoni histone deacetylase 0.0086 0.023 0.023
Brugia malayi cathepsin L-like precursor 0.069 0.228 0.228
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Echinococcus multilocularis Regulator of G protein signaling 20 0.0043 0.0082 0.0082
Echinococcus multilocularis histone deacetylase 0.0097 0.0267 0.0267
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0031 0.0042 0.0042
Giardia lamblia Serine peptidase, putative 0.0104 0.0289 0.0788
Onchocerca volvulus 0.0035 0.0057 0.01
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0842 0.2795 0.2794
Echinococcus granulosus cathepsin l1 0.0989 0.3297 0.3297
Toxoplasma gondii centrin, putative 0.0136 0.0397 0.0696
Trypanosoma brucei cysteine peptidase, putative 0.0247 0.0776 0.1356
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0043 0.0082 0.0082
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0172 0.017
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0172 0.0297
Entamoeba histolytica cysteine protease, putative 0.0251 0.0789 0.2389
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0251 0.0789 0.2165
Trypanosoma cruzi cysteine proteinase, putative 0.055 0.1806 0.1804
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0089 0.0239 0.0516
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0082 0.0082
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Leishmania major cathepsin L-like protease 0.1094 0.3652 0.6392
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0251 0.0789 0.0789
Brugia malayi Pre-SET motif family protein 0.0065 0.0158 0.0158
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.055 0.1806 0.1804
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0025 0.002 0.0061
Schistosoma mansoni hypothetical protein 0.0024 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0086 0.023 0.023
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0247 0.0776 0.2134
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0002 0.0002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Schistosoma mansoni centrin 0.0136 0.0397 0.0397
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Schistosoma mansoni cathepsin B (C01 family) 0.0251 0.0789 0.0789
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0251 0.0789 0.2165
Echinococcus multilocularis proteasome (prosome, macropain) 0.0089 0.0239 0.0239
Echinococcus granulosus neurocalcin 0.0136 0.0397 0.0397
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0012 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0382 0.1477
Loa Loa (eye worm) hypothetical protein 0.0054 0.0122 0.0122
Onchocerca volvulus Deterin homolog 0.0186 0.057 0.0998
Echinococcus granulosus histone deacetylase 0.0097 0.0267 0.0267
Entamoeba histolytica hypothetical protein 0.0043 0.0082 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0012 0.0012
Echinococcus multilocularis transmembrane protease serine 3 0.0066 0.0161 0.0161
Leishmania major histone deacetylase, putative 0.0097 0.0267 0.0463
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0327 0.1049 0.2882
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0082 0.0225
Echinococcus multilocularis calpain 7 (C02 family) 0.0842 0.2795 0.2795
Entamoeba histolytica grainin 2 0.0139 0.041 0.1237
Plasmodium falciparum histone deacetylase, putative 0.0097 0.0267 0.0809
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0012 0.0012
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1373 0.46 1
Echinococcus multilocularis cysteine protease 0.0989 0.3297 0.3297
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0305 0.0839
Echinococcus multilocularis microtubule associated protein 2 0.1517 0.509 0.509
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0012 0.0012
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0251 0.0789 0.2389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Trypanosoma cruzi histone deacetylase, putative 0.0097 0.0267 0.0264
Loa Loa (eye worm) hypothetical protein 0.0065 0.0158 0.0158
Echinococcus granulosus dnaJ subfamily B 0.0418 0.1356 0.1356
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0247 0.0776 0.2134
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0397 0.1092
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0104 0.0289 0.087
Echinococcus multilocularis Mastin 0.0066 0.0161 0.0161
Onchocerca volvulus 0.0251 0.0789 0.1382
Onchocerca volvulus 0.0065 0.0158 0.0277
Schistosoma mansoni hypothetical protein 0.0186 0.057 0.057
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Onchocerca volvulus 0.0029 0.0037 0.0064
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0174
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0083 0.025
Trypanosoma cruzi I/6 autoantigen, putative 0.0136 0.0397 0.0395
Loa Loa (eye worm) cathepsin B 0.109 0.3638 0.3638
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0083 0.008
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0172 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0082 0.0225
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0289 0.0794
Schistosoma mansoni calpain-7 (C02 family) 0.0845 0.2806 0.2806
Echinococcus multilocularis calpain family protein 1, d 0.1651 0.5543 0.5543
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0382 0.0669
Plasmodium vivax unspecified product 0.0251 0.0789 0.2394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.0082 0.0082
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0251 0.0789 0.2394
Loa Loa (eye worm) hypothetical protein 0.0066 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0043 0.0082 0.0082
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0047 0.0096 0.0365
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.4892
Brugia malayi regulator of G-protein signaling rgs-7 0.0043 0.0082 0.0082
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0104 0.0289 0.0794
Loa Loa (eye worm) hypothetical protein 0.0247 0.0776 0.0776
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0035 0.0057 0.0057
Brugia malayi calpain family protein 1 0.2245 0.7562 0.7562
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0057 0.0214
Schistosoma mansoni endothelin-converting enzyme-related 0.0022 0.0013 0.0013
Trichomonas vaginalis myosin light chain 1, putative 0.0136 0.0397 0.1092
Leishmania major cathepsin L-like protease 0.0989 0.3297 0.577
Trypanosoma brucei antigen, putative 0.0842 0.2795 0.4892
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0002 0.0002
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0136 0.0397 0.0397
Loa Loa (eye worm) zinc metallopeptidase 4 0.0022 0.0013 0.0013
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0148 0.0148
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0066 0.0161 0.0161
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0078 0.0137
Echinococcus granulosus centrin 2 0.0136 0.0397 0.0397
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0247 0.0776 0.0774
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0057 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.4892
Schistosoma mansoni neuronal calcium sensor 0.0136 0.0397 0.0397
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.1201 0.4017 0.7031
Schistosoma mansoni Mername-AA248 (C02 family) 0.0842 0.2795 0.2795
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0082 0.0225
Trypanosoma brucei Calpain-like protein 2 0.0247 0.0776 0.1356
Trypanosoma cruzi major cysteine proteinase, putative 0.0251 0.0789 0.0787
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0082 0.0082
Plasmodium vivax hypothetical protein, conserved 0.0138 0.0405 0.123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0012 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0043 0.0082 0.0082
Echinococcus granulosus Dipeptidyl peptidase 9 0.1201 0.4017 0.4017
Schistosoma mansoni calpain (C02 family) 0.0842 0.2795 0.2795
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0082 0.0225
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0247 0.0776 0.1356
Loa Loa (eye worm) hypothetical protein 0.0035 0.0057 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.055 0.1806 0.3159
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0172 0.0522
Brugia malayi Cathepsin L-like precursor 0.0299 0.0953 0.0953
Onchocerca volvulus 0.1403 0.4703 0.8234
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0012 0.0012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0002 0.0002
Mycobacterium ulcerans zinc metalloprotease 0.0092 0.025 0.0963
Loa Loa (eye worm) PXA domain-containing protein 0.0043 0.0082 0.0082
Echinococcus granulosus gamma secretase subunit aph 1 0.0252 0.0792 0.0792
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.023 0.0633
Mycobacterium tuberculosis Conserved protein 0.0215 0.0666 0.1443
Brugia malayi Papain family cysteine protease containing protein 0.0251 0.0789 0.0789
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0172 0.0172
Schistosoma mansoni mitochondrial solute carrier 0.0136 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0251 0.0789 0.0789
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2963 1 1
Brugia malayi Cytochrome P450 family protein 0.0035 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0043 0.0082 0.0082
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.4892
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0006
Trypanosoma cruzi conserved protein 0.0247 0.0776 0.0774
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0012 0.0012
Leishmania major calmodulin-like protein 0.0136 0.0397 0.0692
Giardia lamblia Encystation-specific protease 0.0251 0.0789 0.2165
Onchocerca volvulus 0.0066 0.0161 0.0282
Loa Loa (eye worm) beta-lactamase 0.0035 0.0057 0.0057
Plasmodium vivax vivapain-1 0.055 0.1806 0.5478
Trypanosoma cruzi histone deacetylase, putative 0.0097 0.0267 0.0264
Echinococcus multilocularis Transglutaminase 0.0215 0.0666 0.0666
Entamoeba histolytica cysteine protease, putative 0.0251 0.0789 0.2389
Mycobacterium ulcerans hypothetical protein 0.0066 0.0161 0.0619
Giardia lamblia Cathepsin L precursor 0.0251 0.0789 0.2165
Echinococcus granulosus calpain 7 C02 family 0.0842 0.2795 0.2795
Brugia malayi programmed cell death protein 6 0.0136 0.0397 0.0397
Trichomonas vaginalis calmodulin, putative 0.0136 0.0397 0.1092
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Plasmodium falciparum histone deacetylase 2 0.0097 0.0267 0.0809
Trypanosoma cruzi caltractin, putative 0.0136 0.0397 0.0395
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0012 0.0012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0842 0.2795 0.2794
Onchocerca volvulus 0.069 0.228 0.3992
Trichomonas vaginalis calcium binding protein, putative 0.0139 0.041 0.1126
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.0006
Schistosoma mansoni hypothetical protein 0.0066 0.0161 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0158 0.0158
Plasmodium falciparum cysteine proteinase falcipain 3 0.0989 0.3297 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0251 0.0789 0.2394
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0174
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.023 0.0633
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0082 0.0082
Trypanosoma brucei calpain-like protein, putative 0.0842 0.2795 0.4892
Echinococcus granulosus calbindin 32 0.0138 0.0405 0.0405
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0327 0.1049 0.2882
Mycobacterium leprae Conserved hypothetical protein 0.0215 0.0666 0.2417
Echinococcus multilocularis calmodulin 0.0136 0.0397 0.0397
Onchocerca volvulus 0.0066 0.0161 0.0282
Trichomonas vaginalis calpain, putative 0.0247 0.0776 0.2134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0156 0.0273
Toxoplasma gondii hypothetical protein 0.0247 0.0776 0.1359
Giardia lamblia Cathepsin L-like protease 0.0251 0.0789 0.2165
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0012 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0251 0.0789 0.0789
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0002 0.0002
Echinococcus granulosus EF hand domain containing family member A2 0.0138 0.0405 0.0405
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0136 0.0397 0.0395
Toxoplasma gondii cathepsin B 0.109 0.3638 0.6369
Onchocerca volvulus 0.0104 0.0289 0.0506
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0158 0.0158
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0022 0.0013 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Brugia malayi prolyl oligopeptidase family protein 0.17 0.5712 0.5712
Leishmania major cysteine peptidase A (CPA) 0.0989 0.3297 0.577
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0251 0.0789 0.0789
Brugia malayi proteasome subunit beta type 2 0.0043 0.0083 0.0083
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0156 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Trichomonas vaginalis calmodulin, putative 0.0136 0.0397 0.1092
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0057 0.0055
Leishmania major centrin, putative,caltractin, putative 0.0136 0.0397 0.0692
Loa Loa (eye worm) glycogen phosphorylase 0.0108 0.0305 0.0305
Schistosoma mansoni hypothetical protein 0.0041 0.0077 0.0077
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Schistosoma mansoni calmodulin related calcium binding protein 0.0136 0.0397 0.0397
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.4892
Schistosoma mansoni histone deacetylase 0.0086 0.023 0.023
Echinococcus granulosus cathepsin l1 0.069 0.228 0.228
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0989 0.3297 0.9062
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.002 0.0018
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0012 0.0012
Plasmodium falciparum centrin-1 0.0136 0.0397 0.1205
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0057 0.0054
Mycobacterium tuberculosis Conserved protein 0.0035 0.0057 0.012
Toxoplasma gondii histone deacetylase HDAC3 0.0086 0.023 0.0403
Schistosoma mansoni centrin-related 0.0136 0.0397 0.0397
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0327 0.1049 0.1049
Echinococcus granulosus calmodulin 0.0136 0.0397 0.0397
Entamoeba histolytica cysteine protease, putative 0.0251 0.0789 0.2389
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0158 0.0158
Trichomonas vaginalis calpain, putative 0.0247 0.0776 0.2134
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0057 0.0057
Brugia malayi EF hand family protein 0.0136 0.0397 0.0397
Leishmania major calmodulin, putative 0.0136 0.0397 0.0692
Brugia malayi peptidase family M13 containing protein 0.0022 0.0013 0.0013
Mycobacterium tuberculosis Conserved hypothetical protein 0.0215 0.0666 0.1443
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Plasmodium vivax calpain, putative 0.0842 0.2795 0.848
Onchocerca volvulus 0.0066 0.0161 0.0282
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0012 0.0012
Trypanosoma brucei prolyl oligopeptidase, putative 0.0776 0.2574 0.4504
Echinococcus granulosus calpain 0.0842 0.2795 0.2795
Echinococcus granulosus histone deacetylase 6 0.0097 0.0267 0.0267
Trichomonas vaginalis set domain proteins, putative 0.0512 0.1676 0.4607
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0355 0.0355
Trypanosoma cruzi cysteine peptidase, putative 0.055 0.1806 0.1804
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0795 0.2636 0.2634
Trypanosoma brucei caltractin, putative 0.0139 0.041 0.0714
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0251 0.0789 0.2394
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0089 0.0239 0.0239
Echinococcus multilocularis endothelin converting enzyme 1 0.0092 0.025 0.025
Trypanosoma brucei Component of motile flagella 41 0.0136 0.0397 0.0692
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0172 0.017
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0043 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0057 0.0057
Schistosoma mansoni cpg binding protein 0.0031 0.0042 0.0042
Toxoplasma gondii histone deacetylase HDAC1 0.0097 0.0267 0.0467
Loa Loa (eye worm) hypothetical protein 0.0104 0.0289 0.0289
Leishmania major hypothetical protein, unknown function 0.0247 0.0776 0.1356
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0251 0.0789 0.2394
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0156 0.0156
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0057 0.012
Echinococcus granulosus tissue type plasminogen activator 0.0025 0.002 0.002
Brugia malayi EF hand family protein 0.0138 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0251 0.0789 0.0789
Onchocerca volvulus Prolyl endopeptidase homolog 0.17 0.5712 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0174
Schistosoma mansoni gamma-secretase subunit aph-1 0.0252 0.0792 0.0792
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.1201 0.4017 0.7031
Echinococcus granulosus calpain A 0.2383 0.803 0.803
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0247 0.0776 0.0774
Plasmodium falciparum serine repeat antigen 5 0.0251 0.0789 0.2394
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0057 0.012
Onchocerca volvulus 0.0025 0.002 0.0035
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0156 0.0156
Onchocerca volvulus Cathepsin L homolog 0.0989 0.3297 0.5772
Trichomonas vaginalis calmodulin, putative 0.0136 0.0397 0.1092
Brugia malayi ecdysteroid receptor 0.0022 0.0012 0.0012
Schistosoma mansoni coup transcription factor 0.0022 0.0012 0.0012
Toxoplasma gondii prolyl endopeptidase 0.17 0.5712 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0092 0.025 0.025
Entamoeba histolytica cysteine protease, putative 0.0251 0.0789 0.2389
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0134 0.0234
Echinococcus multilocularis cathepsin b 0.2963 1 1
Plasmodium falciparum serine repeat antigen 3 0.0251 0.0789 0.2394
Echinococcus multilocularis calpain 5 0.0842 0.2795 0.2795
Trichomonas vaginalis esterase, putative 0.0035 0.0057 0.0157
Trypanosoma brucei calpain, putative 0.0247 0.0776 0.1356
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0057 0.0057
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0156 0.0273
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0082 0.0082
Trypanosoma brucei calmodulin, putative 0.0136 0.0397 0.0692
Schistosoma mansoni neuronal calcium sensor 0.0136 0.0397 0.0397
Echinococcus multilocularis EF hand domain containing family member A2 0.0138 0.0405 0.0405
Giardia lamblia Cathepsin B precursor 0.0251 0.0789 0.2165
Brugia malayi carbohydrate phosphorylase 0.0108 0.0305 0.0305
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0989 0.3297 0.3297
Trichomonas vaginalis calcium binding protein, putative 0.0136 0.0397 0.1092
Brugia malayi hypothetical protein 0.0043 0.0082 0.0082
Brugia malayi nuclear receptor NHR-88 0.0022 0.0012 0.0012
Onchocerca volvulus 0.0166 0.0501 0.0877
Trypanosoma brucei calpain-like protein, putative 0.0842 0.2795 0.4892
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0136 0.0397 0.0692
Trypanosoma brucei I/6 autoantigen 0.0136 0.0397 0.0692
Schistosoma mansoni reticulocalbin 0.0138 0.0405 0.0405
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Brugia malayi prolyl oligopeptidase family protein 0.1201 0.4017 0.4017
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.17 0.5712 0.5712
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0158 0.0277
Trichomonas vaginalis calcium binding protein, putative 0.0136 0.0397 0.1092
Schistosoma mansoni ef hand domain family member A2 0.0136 0.0397 0.0397
Trypanosoma cruzi oligopeptidase b 0.0776 0.2574 0.2572
Echinococcus multilocularis calpain A 0.2383 0.803 0.803
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0089 0.0239 0.0239
Toxoplasma gondii cathepsin CPL 0.0989 0.3297 0.5772
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Plasmodium falciparum serine repeat antigen 8 0.0251 0.0789 0.2394
Echinococcus granulosus enteropeptidase 0.0066 0.0161 0.0161
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0382 0.0665
Schistosoma mansoni hypothetical protein 0.0136 0.0397 0.0397
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0136 0.0397 0.0692
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0104 0.0289 0.0289
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0066 0.0161 0.0161
Entamoeba histolytica calcium binding family protein 0.0136 0.0397 0.1199
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0989 0.3297 0.3297
Mycobacterium leprae probable zinc metalloprotease 0.0092 0.025 0.0766
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.2794
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0057 0.0157
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0989 0.3297 1
Leishmania major hypothetical protein, conserved 0.0247 0.0776 0.1356
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0382 0.0382
Brugia malayi Histone deacetylase family protein 0.0097 0.0267 0.0267
Mycobacterium tuberculosis Conserved hypothetical protein 0.0215 0.0666 0.1443
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0012 0.002
Trypanosoma brucei centrin, putative 0.0136 0.0397 0.0692
Brugia malayi CXXC zinc finger family protein 0.0029 0.0037 0.0037
Entamoeba histolytica hypothetical protein, conserved 0.0327 0.1049 0.3176
Entamoeba histolytica calmodulin, putative 0.0136 0.0397 0.1199
Giardia lamblia Cathepsin B precursor 0.0251 0.0789 0.2165
Schistosoma mansoni inhibitor of apoptosis protein 0.0186 0.057 0.057
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0083 0.008
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0089 0.0239 0.0416
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0043 0.0082 0.0082
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0252 0.0252
Entamoeba histolytica hypothetical protein 0.0043 0.0082 0.0241
Giardia lamblia Cathepsin B precursor 0.109 0.3638 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0012 0.0012
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0172 0.0473
Echinococcus granulosus Mastin 0.0066 0.0161 0.0161
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0251 0.0789 0.2394
Echinococcus multilocularis prolyl endopeptidase 0.17 0.5712 0.5712
Echinococcus multilocularis histone deacetylase 7 0.0097 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0035 0.0057 0.0057
Echinococcus multilocularis cathepsin b 0.2963 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0057 0.0157
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0247 0.0776 0.0774
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Leishmania major oligopeptidase b 0.0776 0.2574 0.4504
Trichomonas vaginalis calmodulin-2, putative 0.0136 0.0397 0.1092
Onchocerca volvulus 0.0989 0.3297 0.5772
Trypanosoma cruzi prolyl endopeptidase 0.17 0.5712 0.5711
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.1201 0.4017 0.4015
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0251 0.0789 0.2394
Leishmania major proteasome beta 5 subunit, putative 0.0089 0.0239 0.0416
Loa Loa (eye worm) trypsin family protein 0.0066 0.0161 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.228 0.6268
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0247 0.0776 0.0774
Brugia malayi Trypsin family protein 0.0066 0.0161 0.0161
Entamoeba histolytica grainin, putative 0.0138 0.0405 0.1224
Echinococcus multilocularis peroxidasin 0.0064 0.0156 0.0156
Schistosoma mansoni cathepsin s 0.0299 0.0953 0.0953
Entamoeba histolytica prolyl oligopeptidase family protein 0.0327 0.1049 0.3176
Toxoplasma gondii cathepsin CPC1 0.0251 0.0789 0.1382
Entamoeba histolytica cysteine protease, putative 0.0251 0.0789 0.2389
Leishmania major calmodulin, putative 0.0136 0.0397 0.0692
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2963 1 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0025 0.002 0.002
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0086 0.023 0.0633
Trypanosoma brucei centrin, putative 0.0136 0.0397 0.0692
Brugia malayi hypothetical protein 0.0098 0.027 0.027
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0252 0.0252
Echinococcus granulosus calpain 5 0.0842 0.2795 0.2795
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0082 0.0082
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0012 0.002
Brugia malayi hypothetical protein 0.0257 0.0809 0.0809
Echinococcus granulosus Glycosyl transferase family 35 0.0108 0.0305 0.0305
Echinococcus multilocularis Dipeptidyl peptidase 9 0.1201 0.4017 0.4017
Echinococcus granulosus expressed protein 0.083 0.2757 0.2757
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0252 0.0252
Schistosoma mansoni rab 0.0136 0.0397 0.0397
Entamoeba histolytica calmodulin, putative 0.0136 0.0397 0.1199
Loa Loa (eye worm) hypothetical protein 0.0043 0.0082 0.0082
Trypanosoma brucei mitochondrial calcium uptake 1 0.0136 0.0397 0.0692
Echinococcus granulosus beta-adrenergic receptor kinase 0.0043 0.0082 0.0082
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0327 0.1049 0.3176
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0082 0.0225
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0251 0.0789 0.0789
Mycobacterium tuberculosis Conserved protein 0.0035 0.0057 0.012
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0078 0.0078
Brugia malayi Cathepsin L-like precursor 0.0989 0.3297 0.3297
Brugia malayi Histone deacetylase family protein 0.0097 0.0267 0.0267
Brugia malayi PXA domain containing protein 0.0043 0.0082 0.0082
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Echinococcus granulosus histone deacetylase 6 0.0103 0.0287 0.0287
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0057 0.012
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0066 0.0161 0.0161
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0022 0.0013 0.0013
Trypanosoma brucei calpain-like protein, putative 0.0842 0.2795 0.4892
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0989 0.3297 0.9062
Loa Loa (eye worm) prolyl oligopeptidase 0.0327 0.1049 0.1049
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0172 0.0297
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0068 0.0168 0.0168
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0082 0.0082
Loa Loa (eye worm) RGS-3 protein 0.0043 0.0082 0.0082
Giardia lamblia Cathepsin L precursor 0.0251 0.0789 0.2165
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0057 0.0157
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0305 0.0919
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0251 0.0789 0.2394
Schistosoma mansoni histone deacetylase 4 5 0.0097 0.0267 0.0267
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0251 0.0789 0.2169
Echinococcus multilocularis histone deacetylase 6 0.0097 0.0267 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Onchocerca volvulus 0.0138 0.0405 0.071
Loa Loa (eye worm) histone deacetylase 7A 0.0097 0.0267 0.0267
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0013 0.0013
Echinococcus granulosus Transglutaminase 0.0215 0.0666 0.0666
Toxoplasma gondii proteasome subunit beta type, putative 0.0089 0.0239 0.0419
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.1201 0.4017 0.7031
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0046 0.0095 0.0095
Onchocerca volvulus 0.0989 0.3297 0.5772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0186 0.057 0.057
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0077 0.0077
Onchocerca volvulus Cathepsin L homolog 0.0989 0.3297 0.5772
Mycobacterium tuberculosis Conserved protein 0.0035 0.0057 0.012
Plasmodium vivax proteasome subunit beta type-5, putative 0.0089 0.0239 0.0726
Onchocerca volvulus 0.0136 0.0397 0.0696
Mycobacterium ulcerans transglutaminase family protein 0.0215 0.0666 0.2579
Trypanosoma cruzi cysteine peptidase, putative 0.1094 0.3652 0.3651
Onchocerca volvulus 0.0989 0.3297 0.5772
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0002 0.5
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0382 0.1477
Loa Loa (eye worm) hypothetical protein 0.0068 0.0168 0.0168
Giardia lamblia Alanyl dipeptidyl peptidase 0.0327 0.1049 0.2878
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0305 0.0305
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0089 0.0239 0.072
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.109 0.3638 0.3638
Giardia lamblia Transglutaminase/protease, putative 0.0215 0.0666 0.1825
Giardia lamblia Cathepsin L precursor 0.0251 0.0789 0.2165
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0136 0.0397 0.1092
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0089 0.0239 0.0237
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Echinococcus granulosus histone deacetylase 7 0.0097 0.0267 0.0267
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0251 0.0789 0.2394
Loa Loa (eye worm) histone deacetylase 3 0.0086 0.023 0.023
Trypanosoma cruzi calmodulin, putative 0.0136 0.0397 0.0395
Plasmodium falciparum serine repeat antigen 9 0.0251 0.0789 0.2394
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0252 0.0792 0.0792
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0247 0.0776 0.0774
Schistosoma mansoni hypothetical protein 0.0024 0.0019 0.0019
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0089 0.0239 0.0658
Loa Loa (eye worm) hypothetical protein 0.0662 0.2184 0.2184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.055 0.1806 0.4964
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0083 0.0227
Brugia malayi Pre-SET motif family protein 0.045 0.1465 0.1465
Echinococcus granulosus caspase 2 0.0098 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0251 0.0789 0.2169
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.1928 0.6485 0.6485
Trypanosoma brucei protein I/6 0.0136 0.0397 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0289 0.0794
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0104 0.0289 0.0287
Toxoplasma gondii hypothetical protein 0.0327 0.1049 0.1836
Brugia malayi Serine protease Z688.6 precursor 0.0104 0.0289 0.0289
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0012 0.0012
Echinococcus granulosus cpg binding protein 0.0031 0.0042 0.0042
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0057 0.0057
Echinococcus granulosus microtubule associated protein 2 0.1517 0.509 0.509
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2963 1 1
Giardia lamblia Cathepsin L precursor 0.0251 0.0789 0.2165
Plasmodium vivax unspecified product 0.055 0.1806 0.5478
Brugia malayi Cell death protein 3 precursor 0.0098 0.027 0.027
Plasmodium vivax histone deacetylase, putative 0.0097 0.0267 0.0809
Brugia malayi Cathepsin L-like cysteine proteinase 0.069 0.228 0.228
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0252 0.0252
Schistosoma mansoni hypothetical protein 0.0247 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Entamoeba histolytica cysteine proteinase 1, putative 0.055 0.1806 0.5475
Loa Loa (eye worm) programmed cell death protein 6 0.0138 0.0405 0.0405
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0136 0.0397 0.0397
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0057 0.0214
Loa Loa (eye worm) hypothetical protein 0.1403 0.4703 0.4703
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0089 0.0239 0.0724
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0012 0.0012
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0305 0.0839
Trypanosoma brucei calpain-like protein, putative 0.0842 0.2795 0.4892
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Trypanosoma cruzi cysteine peptidase, putative 0.1094 0.3652 0.3651
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.0789 0.2169
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0013 0.0013
Trypanosoma brucei kinesin, putative 0.0594 0.1956 0.3422
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0096 0.0204
Schistosoma mansoni cathepsin F (C01 family) 0.0989 0.3297 0.3297
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0842 0.2795 0.2794
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Leishmania major cathepsin L-like protease 0.0989 0.3297 0.577
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0083 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0251 0.0789 0.2169
Trichomonas vaginalis calmodulin, putative 0.0138 0.0405 0.1115
Echinococcus multilocularis cpg binding protein 0.0031 0.0042 0.0042
Trypanosoma cruzi major cysteine proteinase, putative 0.0356 0.1145 0.1143
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0012 0.0012
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0382 0.0382
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0057 0.0211
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0083 0.025
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0251 0.0789 0.0789
Onchocerca volvulus 0.0989 0.3297 0.5772
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0002 0.0002
Trypanosoma cruzi centrin-3 0.0139 0.041 0.0408
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0172 0.0515
Schistosoma mansoni hypothetical protein 0.0024 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0104 0.0289 0.0289
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0252 0.0252
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0086 0.023 0.0633
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.0774
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0251 0.0789 0.0789
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0251 0.0789 0.2169
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0842 0.2795 0.2794
Giardia lamblia Hypothetical protein 0.0251 0.0789 0.2165
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0082 0.0082
Entamoeba histolytica cysteine proteinase, putative 0.055 0.1806 0.5475
Loa Loa (eye worm) hypothetical protein 0.0066 0.0161 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0057 0.012
Onchocerca volvulus 0.0064 0.0156 0.0273
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0247 0.0776 0.1359
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Giardia lamblia Thymus-specific serine protease precursor 0.0104 0.0289 0.0788
Echinococcus multilocularis centrin 2 0.0136 0.0397 0.0397
Giardia lamblia Cysteine protease 0.0251 0.0789 0.2165
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0104 0.0289 0.0287
Plasmodium falciparum serine repeat antigen 7 0.0251 0.0789 0.2394
Echinococcus multilocularis acylamino acid releasing enzyme 0.0327 0.1049 0.1049
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0066 0.0161 0.0161
Echinococcus granulosus EF HAND 1 calcium binding site 0.0136 0.0397 0.0397
Trypanosoma brucei cysteine peptidase C (CPC) 0.109 0.3638 0.6368
Brugia malayi histone deacetylase 1 (HD1) 0.0086 0.023 0.023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0012 0.0012
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0096 0.0096
Loa Loa (eye worm) ctsf protein 0.0989 0.3297 0.3297
Trypanosoma brucei calpain, putative 0.0247 0.0776 0.1356
Trichomonas vaginalis calpain, putative 0.0247 0.0776 0.2134
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0251 0.0789 0.2165
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2381 0.8022 0.8022
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0002 0.0002
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0156 0.0156
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.17 0.5712 0.5712
Echinococcus multilocularis histone deacetylase 6 0.0097 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0064 0.0156 0.0156
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0776 0.2574 0.5593
Trichomonas vaginalis calmodulin, putative 0.0136 0.0397 0.1092
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0161 0.0161
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0305 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0012 0.0012
Toxoplasma gondii calmodulin CAM1 0.0138 0.0405 0.071
Loa Loa (eye worm) hypothetical protein 0.0186 0.057 0.057
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0156 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Echinococcus granulosus histone deacetylase 1 0.0086 0.023 0.023
Brugia malayi Serine carboxypeptidase S28 family protein 0.0104 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0359 0.1155 0.1155
Echinococcus multilocularis beta adrenergic receptor kinase 0.0043 0.0082 0.0082
Loa Loa (eye worm) cysteine protease 0.0989 0.3297 0.3297
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.1998 0.6722 0.6722
Plasmodium falciparum peptidase, putative 0.0327 0.1049 0.3181
Entamoeba histolytica hypothetical protein, conserved 0.0138 0.0405 0.1224
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0082 0.0082
Trypanosoma cruzi kinesin, putative 0.0594 0.1956 0.1954
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0247 0.0776 0.0774
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0156 0.0273
Leishmania major cathepsin L-like protease 0.0989 0.3297 0.577
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0251 0.0789 0.2394
Leishmania major calpain protease-like protein 0.0247 0.0776 0.1356
Echinococcus granulosus apoptotic protease activating factor 1 0.0098 0.027 0.027
Leishmania major C-8 sterol isomerase-like protein 0.0359 0.1155 0.202
Giardia lamblia Cysteine protease 0.0251 0.0789 0.2165
Brugia malayi Peptidase family M13 containing protein 0.0092 0.025 0.025
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.157 0.5268 0.5268
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0247 0.0776 0.1356
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0141 0.0141
Brugia malayi Papain family cysteine protease containing protein 0.0989 0.3297 0.3297
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0057 0.0096
Loa Loa (eye worm) calmodulin-like protein 0.0136 0.0397 0.0397
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0141 0.0141
Echinococcus granulosus cathepsin b 0.2963 1 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0289 0.0794
Loa Loa (eye worm) hypothetical protein 0.0098 0.027 0.027
Brugia malayi calpain 5 0.0594 0.1956 0.1956
Echinococcus granulosus tumor protein p63 0.0371 0.1198 0.1198
Schistosoma mansoni hypothetical protein 0.0418 0.1356 0.1356
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.002
Brugia malayi nuclear hormone receptor 0.0022 0.0012 0.0012
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0136 0.0397 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0082 0.0082
Echinococcus multilocularis programmed cell death protein 0.0139 0.041 0.041
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Mycobacterium leprae Conserved hypothetical protein 0.0215 0.0666 0.2417
Echinococcus multilocularis histone deacetylase 1 0.0086 0.023 0.023
Leishmania major protein kinase, putative 0.0136 0.0397 0.0692
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0186 0.057 0.057
Loa Loa (eye worm) hypothetical protein 0.0186 0.057 0.057
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0068 0.0168 0.0168
Onchocerca volvulus 0.0066 0.0161 0.0282
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0136 0.0397 0.0395
Trypanosoma brucei oligopeptidase b 0.0776 0.2574 0.4504
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0156 0.0156
Plasmodium vivax centrin-1, putative 0.0136 0.0397 0.1205
Echinococcus multilocularis cysteine protease 0.0989 0.3297 0.3297
Brugia malayi Cathepsin L-like precursor 0.0989 0.3297 0.3297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1094 0.3652 0.6392
Loa Loa (eye worm) calpain family protein 1 0.2245 0.7562 0.7562
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0104 0.0289 0.0287
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0083 0.0083
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.109 0.3638 0.6368
Onchocerca volvulus 0.0989 0.3297 0.5772
Brugia malayi Serine protease Z688.6 precursor 0.0104 0.0289 0.0289
Echinococcus granulosus Regulator of G protein signaling 20 0.0043 0.0082 0.0082
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0186 0.057 0.057
Loa Loa (eye worm) hypothetical protein 0.0136 0.0397 0.0397
Echinococcus multilocularis calcium uptake protein 1 0.0138 0.0405 0.0405
Brugia malayi Papain family cysteine protease containing protein 0.0251 0.0789 0.0789
Schistosoma mansoni hypothetical protein 0.0215 0.0666 0.0666
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0247 0.0776 0.0774
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0174
Brugia malayi Cathepsin L-like precursor 0.0989 0.3297 0.3297
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0989 0.3297 0.9062
Brugia malayi MH2 domain containing protein 0.0123 0.0355 0.0355
Brugia malayi Cytochrome P450 family protein 0.0035 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0012 0.0012
Giardia lamblia Cathepsin B precursor 0.0251 0.0789 0.2165
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0012 0.0012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0002 0.0002
Brugia malayi hypothetical protein 0.054 0.1769 0.1769
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.0035 0.0057 0.0096
Trichomonas vaginalis centrin, putative 0.0136 0.0397 0.1092
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0251 0.0789 0.2169
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0186 0.057 0.057
Entamoeba histolytica cysteine protease, putative 0.055 0.1806 0.5475
Trichomonas vaginalis centrin, putative 0.0136 0.0397 0.1092
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0104 0.0289 0.0794
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0012 0.0012
Brugia malayi Proteasome A-type and B-type family protein 0.0089 0.0239 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.109 0.3638 1
Echinococcus granulosus neuronal calcium sensor 0.0136 0.0397 0.0397
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0104 0.0289 0.0506
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0251 0.0789 0.2169
Echinococcus multilocularis calumenin 0.0138 0.0405 0.0405
Schistosoma mansoni hypothetical protein 0.0098 0.027 0.027
Brugia malayi beta-lactamase family protein 0.0035 0.0057 0.0057
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0052 0.0115 0.0115
Echinococcus multilocularis tumor protein p63 0.0371 0.1198 0.1198
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0251 0.0789 0.0789
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0247 0.0776 0.2134
Mycobacterium ulcerans beta-lactamase 0.0035 0.0057 0.0214
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.069 0.228 0.228
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0104 0.0289 0.087
Trypanosoma cruzi histone deacetylase, putative 0.0097 0.0267 0.0264
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0012 0.0012
Echinococcus granulosus cathepsin L 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0166 0.0501 0.0501
Entamoeba histolytica cysteine proteinase, putative 0.0989 0.3297 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0156 0.0156
Trichomonas vaginalis hypothetical protein 0.0247 0.0776 0.2134
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0327 0.1049 0.3176
Trypanosoma brucei Calpain-like protein CALP1.3 0.0247 0.0776 0.1356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0989 0.3297 0.9062
Schistosoma mansoni calpain-2 (C02 family) 0.0247 0.0776 0.0776
Onchocerca volvulus Cathepsin F homolog 0.0989 0.3297 0.5772
Schistosoma mansoni histone deacetylase hda2 0.0103 0.0287 0.0287
Toxoplasma gondii calcium-dependent protein kinase 0.0138 0.0405 0.071
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0092 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Echinococcus granulosus cathepsin L 0.055 0.1806 0.1806
Schistosoma mansoni hypothetical protein 0.0025 0.002 0.002
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0057 0.012
Brugia malayi Papain family cysteine protease containing protein 0.055 0.1806 0.1806
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0082 0.0082
Toxoplasma gondii preprocathepsin c precursor, putative 0.0251 0.0789 0.1382
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0842 0.2795 0.2794
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0078 0.0078
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0012 0.0012
Entamoeba histolytica prolyl oligopeptidase family protein 0.0327 0.1049 0.3176
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0989 0.3297 0.3297
Giardia lamblia Hypothetical protein 0.0251 0.0789 0.2165
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0251 0.0789 0.2394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.055 0.1806 0.4964
Onchocerca volvulus Peroxidase homolog 0.0064 0.0156 0.0273
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.023 0.0633
Plasmodium falciparum serine repeat antigen 2 0.0251 0.0789 0.2394
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0251 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0299 0.0953 0.0953
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0082 0.0082
Loa Loa (eye worm) EF hand family protein 0.0136 0.0397 0.0397
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.023 0.0633
Echinococcus granulosus transmembrane protease serine 3 0.0066 0.0161 0.0161
Echinococcus granulosus cysteine protease 0.055 0.1806 0.1806

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.5481 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 25.929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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