Detailed information for compound 1413911

Basic information

Technical information
  • TDR Targets ID: 1413911
  • Name: 1-(2-methyl2,3-dihydro-1,4-benzoxazine-4-carb onyl)-N-(thiophen-2-ylmethyl)piperidine-4-car boxamide
  • MW: 399.507 | Formula: C21H25N3O3S
  • H donors: 1 H acceptors: 2 LogP: 2.45 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1Oc2ccccc2N(C1)C(=O)N1CCC(CC1)C(=O)NCc1cccs1
  • InChi: 1S/C21H25N3O3S/c1-15-14-24(18-6-2-3-7-19(18)27-15)21(26)23-10-8-16(9-11-23)20(25)22-13-17-5-4-12-28-17/h2-7,12,15-16H,8-11,13-14H2,1H3,(H,22,25)
  • InChiKey: TYMLQJYZTUFLHV-UHFFFAOYSA-N  


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Synonyms

  • 1-(2-methyl2,3-dihydro-1,4-benzoxazine-4-carbonyl)-N-(2-thienylmethyl)piperidine-4-carboxamide
  • 1-[(2-methyl-2,3-dihydro-1,4-benzoxazin-4-yl)-oxomethyl]-N-(2-thienylmethyl)-4-piperidinecarboxamide
  • 1-(2-methyl2,3-dihydro-1,4-benzoxazine-4-carbonyl)-N-(2-thienylmethyl)isonipecotamide
  • 1-[(2-methyl-2,3-dihydro-1,4-benzoxazin-4-yl)carbonyl]-N-(thiophen-2-ylmethyl)piperidine-4-carboxamide
  • E216-0642
  • NCGC00121483-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Equus caballus Ferritin light chain Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Trichomonas vaginalis calmodulin-2, putative 0.0224 0.0411 0.1124
Brugia malayi cathepsin F-like cysteine proteinase 0.0397 0.0768 0.0767
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0145 0.0247 0.0543
Loa Loa (eye worm) hypothetical protein 0.0397 0.0768 0.0768
Trichomonas vaginalis myosin light chain 1, putative 0.0224 0.0411 0.1124
Toxoplasma gondii EFHC1, putative 0.0224 0.0411 0.0909
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0041 0.0031 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Echinococcus granulosus neural cadherin 0.0044 0.0037 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.017 0.046
Loa Loa (eye worm) hypothetical protein 0.0076 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0139 0.0233 0.0233
Onchocerca volvulus 0.081 0.1622 0.3339
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0397 0.0768 0.2439
Loa Loa (eye worm) calpain D 0.0415 0.0806 0.0806
Loa Loa (eye worm) hypothetical protein 0.0101 0.0155 0.0155
Echinococcus multilocularis calpain 0.142 0.2885 0.2885
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0397 0.0768 0.2112
Plasmodium vivax hypothetical protein, conserved 0.0173 0.0305 0.0961
Loa Loa (eye worm) hypothetical protein 0.0201 0.0363 0.0363
Leishmania major proteasome alpha 1 subunit, putative 0.0041 0.0031 0.0061
Toxoplasma gondii preprocathepsin c precursor, putative 0.0397 0.0768 0.1707
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0036
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0031 0.0027
Echinococcus multilocularis transmembrane protease serine 3 0.0201 0.0363 0.0362
Loa Loa (eye worm) hypothetical protein 0.0221 0.0403 0.0403
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Echinococcus granulosus centrin 2 0.0224 0.0411 0.041
Brugia malayi prolyl oligopeptidase family protein 0.0257 0.0478 0.0477
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0142 0.0241 0.053
Giardia lamblia Transglutaminase/protease, putative 0.0291 0.0548 0.1503
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.017 0.0169
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0013 0.0012
Trypanosoma cruzi caltractin, putative 0.0224 0.0411 0.0407
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0889 0.1787 0.4517
Echinococcus granulosus subfamily T1A non peptidase ue 0.0041 0.0031 0.003
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0041 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0201 0.0363 0.0363
Onchocerca volvulus 0.0045 0.004 0.0081
Toxoplasma gondii prolyl endopeptidase 0.2191 0.4481 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0194 0.0425
Brugia malayi beta-lactamase 0.0108 0.017 0.0169
Brugia malayi Papain family cysteine protease containing protein 0.0397 0.0768 0.0767
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.4017 0.8259 0.8259
Schistosoma mansoni caspase-7 (C14 family) 0.0386 0.0745 0.0744
Onchocerca volvulus 0.0108 0.017 0.0349
Schistosoma mansoni calpain-7 (C02 family) 0.1423 0.2892 0.2891
Loa Loa (eye worm) hypothetical protein 0.0394 0.0762 0.0762
Leishmania major cathepsin L-like protease 0.1542 0.3137 0.7
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0039 0.0038
Leishmania major metacaspase, putative 0.0173 0.0305 0.0673
Trypanosoma brucei centrin, putative 0.0224 0.0411 0.0909
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0041 0.0031 0.003
Brugia malayi cathepsin F-like cysteine proteinase 0.0464 0.0907 0.0906
Schistosoma mansoni chromatin regulatory protein sir2 0.0139 0.0233 0.0232
Loa Loa (eye worm) hypothetical protein 0.0108 0.017 0.017
Giardia lamblia 20S proteasome alpha subunit 4 0.0041 0.0031 0.0075
Echinococcus granulosus cathepsin b 0.4858 1 1
Brugia malayi EF hand family protein 0.0224 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0108 0.017 0.017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Loa Loa (eye worm) hypothetical protein 0.0076 0.0104 0.0104
Giardia lamblia 20S proteasome alpha subunit 5 0.0041 0.0031 0.0075
Giardia lamblia Cathepsin L precursor 0.0397 0.0768 0.2112
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1777 0.3623 0.3623
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Echinococcus multilocularis glycoprotein Antigen 5 0.0201 0.0363 0.0362
Trypanosoma brucei calpain, putative 0.0415 0.0806 0.1791
Brugia malayi Trypsin family protein 0.0201 0.0363 0.0362
Echinococcus granulosus cathepsin L cysteine proteinase 0.1542 0.3137 0.3137
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.0806 0.0802
Giardia lamblia Cathepsin B precursor 0.0397 0.0768 0.2112
Onchocerca volvulus 0.0045 0.004 0.0081
Echinococcus granulosus cysteine protease 0.0861 0.1729 0.1728
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0397 0.0768 0.2112
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.017 0.0169
Echinococcus multilocularis endothelin converting enzyme 1 0.0101 0.0155 0.0154
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0041 0.0031 0.0027
Loa Loa (eye worm) animal heme peroxidase 0.0499 0.0979 0.0979
Entamoeba histolytica prolyl oligopeptidase family protein 0.0257 0.0478 0.1512
Loa Loa (eye worm) hypothetical protein 0.3377 0.6935 0.6935
Echinococcus granulosus proteasome subunit beta type 6 0.0041 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Onchocerca volvulus Cathepsin L homolog 0.1542 0.3137 0.6461
Schistosoma mansoni histone deacetylase 0.0089 0.013 0.0129
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0039 0.0038
Trichomonas vaginalis calcium binding protein, putative 0.0224 0.0411 0.1124
Trypanosoma cruzi metacaspase 5, putative 0.0173 0.0305 0.0301
Leishmania major cathepsin L-like protease 0.1652 0.3365 0.7507
Schistosoma mansoni neuronal calcium sensor 0.0224 0.0411 0.041
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0253 0.047 0.047
Echinococcus granulosus Transglutaminase 0.0291 0.0548 0.0547
Mycobacterium tuberculosis Conserved protein 0.0291 0.0548 0.1374
Plasmodium vivax histone deacetylase, putative 0.0043 0.0035 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.0305 0.0832
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0354 0.0679 0.1508
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0861 0.1729 0.3853
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0276 0.0518 0.0518
Loa Loa (eye worm) PAS-3 protein 0.0041 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0049 0.0047 0.0047
Toxoplasma gondii histone deacetylase HDAC1 0.01 0.0152 0.0332
Echinococcus granulosus programmed cell death protein 0.0232 0.0426 0.0425
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Toxoplasma gondii proteasome subunit 0.0041 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0224 0.0411 0.041
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Echinococcus granulosus cathepsin L cysteine protease 0.0861 0.1729 0.1728
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Schistosoma mansoni calmodulin related calcium binding protein 0.0224 0.0411 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0013 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0397 0.0768 0.2112
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0354 0.0679 0.1508
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0257 0.0478 0.1309
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Trichomonas vaginalis calcium binding protein, putative 0.0224 0.0411 0.1124
Echinococcus granulosus histone deacetylase 0.01 0.0152 0.0151
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0041 0.0031 0.0087
Brugia malayi Calmodulin-like protein 0.0224 0.0411 0.041
Giardia lamblia Hypothetical protein 0.0291 0.0548 0.1503
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Leishmania major cathepsin L-like protease 0.1542 0.3137 0.7
Leishmania major histone deacetylase, putative 0.0089 0.013 0.0281
Loa Loa (eye worm) calpain family protein 1 0.3792 0.7795 0.7795
Trichomonas vaginalis centrin, putative 0.0224 0.0411 0.1124
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.2883
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.1652 0.3365 0.3362
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0037 0.0023 0.0097
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.142 0.2885 0.6436
Trypanosoma brucei cytochrome P450, putative 0.0037 0.0023 0.0043
Brugia malayi beta-lactamase family protein 0.0108 0.017 0.0169
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0039 0.0038
Echinococcus granulosus neurogenic locus protein delta 0.0044 0.0037 0.0036
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0228 0.0418 0.0417
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0248 0.0248
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0031 0.0061
Trypanosoma brucei oligopeptidase b 0.0889 0.1787 0.3983
Trypanosoma cruzi centrin-3 0.0232 0.0426 0.0422
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0206 0.0558
Schistosoma mansoni gabp alpha 0.0071 0.0093 0.0092
Giardia lamblia Alanyl dipeptidyl peptidase 0.0257 0.0478 0.1309
Brugia malayi Trypsin family protein 0.0201 0.0363 0.0362
Brugia malayi histone deacetylase 3 (HD3) 0.0089 0.013 0.0129
Trypanosoma brucei hypothetical protein, conserved 0.0224 0.0411 0.0909
Brugia malayi Papain family cysteine protease containing protein 0.1542 0.3137 0.3137
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0397 0.0768 0.2439
Trichomonas vaginalis calmodulin, putative 0.0224 0.0411 0.1124
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0692 0.1378 0.3479
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Echinococcus multilocularis protein jagged 1 0.0044 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0187 0.0333 0.0332
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0039 0.0038
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0041 0.0031 0.0061
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0224 0.0411 0.041
Leishmania major centrin, putative 0.0224 0.0411 0.0909
Mycobacterium tuberculosis Hypothetical protein 0.0291 0.0548 0.1374
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0605 0.1199 0.1198
Leishmania major calmodulin-like protein 0.0224 0.0411 0.0909
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0101 0.0101
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0397 0.0768 0.2439
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Brugia malayi Animal haem peroxidase family protein 0.0499 0.0979 0.0978
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0039 0.0097
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.004 0.004
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0093 0.0093
Brugia malayi regulator of G-protein signaling egl-10 0.0045 0.0039 0.0038
Brugia malayi hypothetical protein 0.0045 0.0039 0.0038
Plasmodium falciparum serine repeat antigen 2 0.0397 0.0768 0.2439
Toxoplasma gondii hypothetical protein 0.0045 0.004 0.0082
Onchocerca volvulus 0.0201 0.0363 0.0745
Echinococcus granulosus cathepsin L 0.0397 0.0768 0.0767
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0047 0.0046
Entamoeba histolytica cysteine proteinase, putative 0.0861 0.1729 0.5504
Loa Loa (eye worm) hypothetical protein 0.0397 0.0768 0.0768
Brugia malayi EGF-like domain containing protein 0.0044 0.0037 0.0036
Onchocerca volvulus 0.1542 0.3137 0.6461
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.142 0.2885 0.2883
Schistosoma mansoni cathepsin D (A01 family) 0.0217 0.0395 0.0395
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0478 0.0474
Onchocerca volvulus 0.0397 0.0768 0.158
Onchocerca volvulus Peroxidasin homolog 0.0499 0.0979 0.2014
Echinococcus granulosus Glycosyl transferase family 35 0.0123 0.02 0.0199
Giardia lamblia Hypothetical protein 0.0397 0.0768 0.2112
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0041 0.0031 0.0087
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0039 0.0038
Trichomonas vaginalis hypothetical protein 0.0415 0.0806 0.2215
Echinococcus multilocularis Transglutaminase 0.0291 0.0548 0.0547
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Plasmodium vivax vivapain-3 0.0861 0.1729 0.5504
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0013 0.003
Trichomonas vaginalis calcineurin B subunit, putative 0.0224 0.0411 0.1124
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0041 0.0031 0.0061
Schistosoma mansoni survival motor neuron protein 0.0058 0.0066 0.0065
Brugia malayi Cell death protein 3 precursor 0.0394 0.0762 0.0761
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0145 0.0247 0.0776
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Leishmania major proteasome alpha 3 subunit, putative 0.0041 0.0031 0.0061
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.0806 0.0802
Mycobacterium tuberculosis Conserved protein 0.0108 0.017 0.0418
Brugia malayi Proteasome subunit alpha type 7-1 0.0041 0.0031 0.003
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0041 0.0031 0.0087
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Brugia malayi programmed cell death protein 6 0.0224 0.0411 0.041
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Brugia malayi NAD-dependent deacetylase SIRT1 0.0139 0.0233 0.0232
Schistosoma mansoni histone deacetylase 0.0089 0.013 0.0129
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Echinococcus granulosus caspase 8 0.0173 0.0305 0.0304
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0415 0.0806 0.0802
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.017 0.046
Trypanosoma cruzi major cysteine proteinase, putative 0.0507 0.0995 0.0992
Plasmodium falciparum serine repeat antigen 7 0.0397 0.0768 0.2439
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.013 0.0348
Trypanosoma brucei calpain-like protein, putative 0.142 0.2885 0.6436
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0039 0.0097
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0006 0.0005
Onchocerca volvulus Histone deacetylase 10 homolog 0.0043 0.0035 0.007
Onchocerca volvulus Peroxidasin homolog 0.0499 0.0979 0.2014
Loa Loa (eye worm) hypothetical protein 0.0043 0.0035 0.0035
Loa Loa (eye worm) calpain 0.142 0.2885 0.2885
Trichomonas vaginalis conserved hypothetical protein 0.0415 0.0806 0.2215
Schistosoma mansoni glycogen phosphorylase 0.0053 0.0056 0.0055
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0013 0.0012
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Brugia malayi Histone deacetylase family protein 0.01 0.0152 0.0151
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0152 0.0149
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Brugia malayi Trypsin family protein 0.0201 0.0363 0.0362
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1078 0.2177 0.6004
Mycobacterium tuberculosis Conserved protein 0.0108 0.017 0.0418
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0044 0.0037 0.0036
Leishmania major cytochrome p450-like protein 0.0037 0.0023 0.0043
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4858 1 1
Echinococcus granulosus proteasome prosome macropain 0.0253 0.047 0.0469
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0253 0.047 0.0466
Brugia malayi mbt repeat family protein 0.0047 0.0043 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.0305 0.0832
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0041 0.0031 0.0087
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0415 0.0806 0.1791
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0464 0.0907 0.0907
Onchocerca volvulus 0.0499 0.0979 0.2014
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.017 0.0169
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0145 0.0247 0.0776
Brugia malayi histone deacetylase 11 0.0043 0.0035 0.0034
Entamoeba histolytica hypothetical protein, conserved 0.0257 0.0478 0.1512
Brugia malayi Papain family cysteine protease containing protein 0.0861 0.1729 0.1728
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0125 0.0206 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0397 0.0768 0.2112
Brugia malayi Cathepsin L-like precursor 0.0464 0.0907 0.0906
Echinococcus multilocularis caspase 8 0.0173 0.0305 0.0304
Trypanosoma cruzi kinesin, putative 0.1005 0.2026 0.2023
Toxoplasma gondii PAN domain-containing protein 0.0045 0.004 0.0082
Echinococcus multilocularis cysteine protease 0.1542 0.3137 0.3137
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0039 0.0038
Brugia malayi Fli-1 protein 0.0216 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0033 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0397 0.0768 0.2112
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0139 0.0233 0.0634
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0056 0.0055
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.0241 0.024
Toxoplasma gondii peptidase, T1 family protein 0.0041 0.0031 0.0061
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.013 0.0348
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0101 0.0155 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Onchocerca volvulus 0.0499 0.0979 0.2014
Brugia malayi calpain D 0.0415 0.0806 0.0805
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0035 0.0071
Brugia malayi proteasome subunit beta type 2 0.0092 0.0137 0.0136
Loa Loa (eye worm) hypothetical protein 0.0076 0.0104 0.0104
Leishmania major calmodulin, putative 0.0224 0.0411 0.0909
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.0137 0.0368
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0201 0.0363 0.0362
Brugia malayi calpain 5 0.1005 0.2026 0.2025
Trypanosoma brucei I/6 autoantigen 0.0224 0.0411 0.0909
Loa Loa (eye worm) histone deacetylase 0.01 0.0152 0.0152
Brugia malayi Proteasome A-type and B-type family protein 0.0253 0.047 0.0469
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0415 0.0806 0.1791
Loa Loa (eye worm) PXA domain-containing protein 0.0045 0.0039 0.0039
Echinococcus granulosus neuronal calcium sensor 0.0224 0.0411 0.041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Loa Loa (eye worm) hypothetical protein 0.0201 0.0363 0.0363
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0142 0.0241 0.0597
Brugia malayi Calcium binding EGF domain containing protein 0.0044 0.0037 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0257 0.0478 0.1309
Loa Loa (eye worm) hypothetical protein 0.0201 0.0363 0.0363
Onchocerca volvulus Cathepsin L homolog 0.1542 0.3137 0.6461
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0013 0.0021
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0041 0.0031 0.0061
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0013 0.0042
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0397 0.0768 0.2439
Mycobacterium tuberculosis Conserved protein 0.0108 0.017 0.0418
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0415 0.0806 0.0802
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Loa Loa (eye worm) TK/ROR protein kinase 0.007 0.0092 0.0092
Plasmodium falciparum serine repeat antigen 9 0.0397 0.0768 0.2439
Onchocerca volvulus 0.0044 0.0037 0.0074
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0224 0.0411 0.041
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0013 0.0012
Echinococcus multilocularis histone deacetylase 6 0.01 0.0152 0.0151
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0248 0.0248
Plasmodium falciparum histone deacetylase 1 0.0089 0.013 0.0402
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0039 0.0038
Echinococcus multilocularis neurogenic locus notch protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0187 0.0333 0.0333
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0145 0.0247 0.0246
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0036
Echinococcus granulosus EF hand domain containing family member A2 0.0224 0.0411 0.041
Schistosoma mansoni lamin 0.0026 0.0001 0.0000090515
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0039 0.0038
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0031 0.0075
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0146 0.0248 0.0247
Echinococcus granulosus dnaJ subfamily B 0.0471 0.0922 0.0921
Schistosoma mansoni neuronal calcium sensor 0.0224 0.0411 0.041
Leishmania major cathepsin L-like protease 0.1542 0.3137 0.7
Schistosoma mansoni centrin-related 0.0224 0.0411 0.041
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0354 0.0679 0.0678
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.142 0.2885 0.2883
Brugia malayi proteasome subunit alpha type 4 0.0041 0.0031 0.003
Mycobacterium leprae Conserved hypothetical protein 0.0291 0.0548 0.3043
Loa Loa (eye worm) fibroinase 0.1542 0.3137 0.3137
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0035 0.0031
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0056 0.0055
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.142 0.2885 0.2883
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0187 0.0333 0.0332
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0041 0.0031 0.0087
Loa Loa (eye worm) hypothetical protein 0.0089 0.013 0.013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.6436
Echinococcus multilocularis histone deacetylase 6 0.0106 0.0165 0.0164
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Brugia malayi GPI-anchor transamidase 0.0034 0.0017 0.0016
Toxoplasma gondii PAN domain-containing protein 0.0045 0.004 0.0082
Onchocerca volvulus Slit protein homolog 0.0044 0.0037 0.0074
Trypanosoma cruzi Aph-1 protein, putative 0.0108 0.0169 0.0165
Schistosoma mansoni inhibitor of apoptosis protein 0.0187 0.0333 0.0332
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0354 0.0679 0.0675
Schistosoma mansoni peroxidasin 0.0499 0.0979 0.0978
Plasmodium vivax proteasome subunit beta type-2, putative 0.0092 0.0137 0.0425
Brugia malayi hypothetical protein 0.0499 0.0979 0.0978
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0861 0.1729 0.1728
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0397 0.0768 0.2112
Echinococcus granulosus neurogenic locus notch protein 0.0044 0.0037 0.0036
Echinococcus multilocularis inhibitor of apoptosis protein 0.0187 0.0333 0.0332
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0043 0.0042
Trypanosoma brucei centrin-3 0.0232 0.0426 0.0942
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Toxoplasma gondii PAN domain-containing protein 0.0045 0.004 0.0082
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0041 0.0031 0.003
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0201 0.0363 0.0362
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0415 0.0806 0.0802
Echinococcus granulosus neurogenic locus notch protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0224 0.0411 0.0411
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0224 0.0411 0.0407
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0187 0.0333 0.0332
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0041 0.0031 0.0027
Onchocerca volvulus 0.0045 0.004 0.0081
Brugia malayi Cathepsin L-like precursor 0.1542 0.3137 0.3137
Echinococcus multilocularis slit 2 protein 0.0044 0.0037 0.0036
Plasmodium falciparum serine repeat antigen 6 0.0397 0.0768 0.2439
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0354 0.0679 0.0675
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Plasmodium falciparum cysteine proteinase falcipain 1 0.0861 0.1729 0.5504
Trypanosoma cruzi cysteine peptidase, putative 0.1652 0.3365 0.3362
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Brugia malayi Trypsin family protein 0.0201 0.0363 0.0362
Trypanosoma cruzi major cysteine proteinase, putative 0.0397 0.0768 0.0765
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4858 1 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0064
Giardia lamblia Cathepsin B precursor 0.1777 0.3623 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0039 0.0038
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0224 0.0411 0.1124
Onchocerca volvulus 0.0499 0.0979 0.2014
Loa Loa (eye worm) MBCTL1 0.0053 0.0056 0.0056
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0023 0.0023
Trichomonas vaginalis calmodulin, putative 0.0224 0.0411 0.1124
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0041 0.0031 0.0027
Echinococcus multilocularis histone deacetylase 8 0.0043 0.0035 0.0034
Plasmodium falciparum proteasome subunit beta type-5 0.0253 0.047 0.1487
Echinococcus multilocularis calmodulin 0.0224 0.0411 0.041
Brugia malayi Trypsin-like protease protein 5 0.0201 0.0363 0.0362
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0006 0.0005
Leishmania major hypothetical protein, conserved 0.0108 0.017 0.0372
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0397 0.0768 0.2439
Echinococcus multilocularis calpain family protein 1, d 0.2787 0.5715 0.5714
Leishmania major cathepsin L-like protease 0.1542 0.3137 0.7
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0861 0.1729 0.1728
Toxoplasma gondii microneme protein MIC17A 0.0045 0.004 0.0082
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0397 0.0768 0.0767
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.004
Echinococcus multilocularis cathepsin L cysteine protease 0.1542 0.3137 0.3137
Entamoeba histolytica calcium-binding protein, putative 0.0224 0.0411 0.1298
Loa Loa (eye worm) hypothetical protein 0.1078 0.2177 0.2177
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0041 0.0031 0.0087
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0013 0.0019
Brugia malayi hypothetical protein 0.0178 0.0315 0.0314
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0039
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0073 0.0073
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0041 0.0031 0.0087
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0013 0.0026
Loa Loa (eye worm) cathepsin B 0.1777 0.3623 0.3623
Entamoeba histolytica hypothetical protein 0.0045 0.0039 0.0112
Echinococcus multilocularis neurogenic locus protein delta 0.0044 0.0037 0.0036
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0224 0.0411 0.1298
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0257 0.0478 0.1512
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0605 0.1199 0.1198
Loa Loa (eye worm) hypothetical protein 0.0397 0.0768 0.0768
Mycobacterium ulcerans hypothetical protein 0.0201 0.0363 0.2005
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0041 0.0031 0.003
Brugia malayi hypothetical protein 0.0282 0.053 0.053
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.142 0.2885 0.2883
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.004
Giardia lamblia High cysteine protein 0.0044 0.0037 0.0092
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0251 0.0682
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Plasmodium falciparum proteasome subunit beta type-4 0.0041 0.0031 0.0087
Mycobacterium ulcerans zinc metalloprotease 0.0101 0.0155 0.084
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0066 0.0065
Schistosoma mansoni hypothetical protein 0.0224 0.0411 0.041
Onchocerca volvulus 0.0045 0.004 0.0081
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0041 0.0031 0.0087
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0053 0.0056 0.0284
Entamoeba histolytica prolyl oligopeptidase family protein 0.0257 0.0478 0.1512
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0041 0.0031 0.0027
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0039 0.0038
Trypanosoma cruzi cysteine peptidase, putative 0.1652 0.3365 0.3362
Brugia malayi hypothetical protein 0.0097 0.0148 0.0147
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0397 0.0768 0.0767
Echinococcus granulosus cathepsin l cysteine peptidase 0.1542 0.3137 0.3137
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0145 0.0247 0.0246
Trypanosoma brucei calpain-like protein, putative 0.142 0.2885 0.6436
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Schistosoma mansoni histone deacetylase hda2 0.0106 0.0165 0.0164
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Plasmodium vivax cysteine repeat modular protein 1, putative 0.007 0.0092 0.0281
Echinococcus multilocularis programmed cell death protein 0.0232 0.0426 0.0425
Trichomonas vaginalis glycogen phosphorylase, putative 0.0123 0.02 0.0543
Onchocerca volvulus Cell death protein 3 homolog 0.0394 0.0762 0.1567
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0253 0.047 0.1288
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Trypanosoma brucei Component of motile flagella 41 0.0224 0.0411 0.0909
Trypanosoma brucei calpain, putative 0.0415 0.0806 0.1791
Echinococcus multilocularis peroxidasin 0.0499 0.0979 0.0978
Echinococcus granulosus calumenin 0.0228 0.0418 0.0417
Loa Loa (eye worm) hypothetical protein 0.0075 0.0101 0.0101
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0041 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0257 0.0478 0.0478
Trypanosoma cruzi metacaspase, putative 0.0173 0.0305 0.0301
Loa Loa (eye worm) hypothetical protein 0.0076 0.0104 0.0104
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0041 0.0031 0.0027
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0041 0.0031 0.5
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0051 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0039
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0145 0.0247 0.0671
Trypanosoma cruzi metacaspase, putative 0.0173 0.0305 0.0301
Loa Loa (eye worm) hypothetical protein 0.1542 0.3137 0.3137
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0093 0.0092
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0861 0.1729 0.1726
Onchocerca volvulus 0.0228 0.0418 0.0859
Echinococcus granulosus calpain 7 C02 family 0.142 0.2885 0.2885
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0017 0.0037
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0145 0.0247 0.0246
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0253 0.047 0.1041
Plasmodium vivax aspartyl protease, putative 0.0189 0.0338 0.1067
Echinococcus granulosus inhibitor of apoptosis protein 0.0187 0.0333 0.0332
Echinococcus multilocularis proteasome subunit beta type 7 0.0041 0.0031 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Loa Loa (eye worm) notch protein 0.0044 0.0037 0.0037
Onchocerca volvulus 0.0291 0.0548 0.1126
Loa Loa (eye worm) calpain 5 0.1005 0.2026 0.2026
Echinococcus multilocularis neurocalcin 0.0224 0.0411 0.041
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Schistosoma mansoni rab 0.0224 0.0411 0.041
Brugia malayi beta-lactamase family protein 0.0108 0.017 0.0169
Brugia malayi Animal haem peroxidase family protein 0.0499 0.0979 0.0978
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0041 0.0031 0.0087
Giardia lamblia 20S proteasome alpha subunit 2 0.0041 0.0031 0.0075
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0041 0.0031 0.0087
Echinococcus granulosus Mastin 0.0201 0.0363 0.0362
Brugia malayi cathepsin L-like precursor 0.1078 0.2177 0.2176
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0206 0.0644
Brugia malayi PXA domain containing protein 0.0045 0.0039 0.0038
Trypanosoma brucei prolyl oligopeptidase, putative 0.0889 0.1787 0.3983
Trichomonas vaginalis set domain proteins, putative 0.0809 0.1621 0.4469
Echinococcus granulosus geminin 0.0342 0.0655 0.0654
Entamoeba histolytica cysteine proteinase, putative 0.1078 0.2177 0.6935
Echinococcus granulosus proteasome subunit alpha type 6 0.0041 0.0031 0.003
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0397 0.0768 0.0767
Leishmania major proteasome beta 2 subunit, putative 0.0041 0.0031 0.0061
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0047 0.0046
Echinococcus multilocularis histone deacetylase 3 0.0089 0.013 0.0129
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0478 0.0474
Onchocerca volvulus Glycogen phosphorylase homolog 0.0123 0.02 0.0411
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0017 0.0037
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0397 0.0768 0.2112
Echinococcus multilocularis apoptotic protease activating factor 1 0.0221 0.0403 0.0402
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Entamoeba histolytica glycogenphosphorylase, putative 0.0053 0.0056 0.0167
Schistosoma mansoni cpg binding protein 0.0065 0.008 0.0079
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0041 0.0031 0.003
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0013 0.0012
Loa Loa (eye worm) EF hand family protein 0.0224 0.0411 0.0411
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.0251 0.025
Brugia malayi Peptidase family M13 containing protein 0.0101 0.0155 0.0154
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0386 0.0745 0.0744
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.017 0.046
Plasmodium falciparum serine repeat antigen 8 0.0397 0.0768 0.2439
Brugia malayi Kringle domain containing protein 0.007 0.0092 0.0091
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.017 0.0372
Brugia malayi Proteasome A-type and B-type family protein 0.0041 0.0031 0.003
Echinococcus multilocularis tissue type plasminogen activator 0.007 0.0092 0.0091
Onchocerca volvulus 0.1078 0.2177 0.4482
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0041 0.0031 0.003
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Echinococcus multilocularis cathepsin b 0.4858 1 1
Trichomonas vaginalis calpain, putative 0.0415 0.0806 0.2215
Mycobacterium ulcerans lipase LipD 0.0108 0.017 0.0925
Onchocerca volvulus 0.0201 0.0363 0.0745
Trypanosoma cruzi prolyl endopeptidase 0.2191 0.4481 0.4479
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0041 0.0031 0.003
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0041 0.0031 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0039 0.0038
Onchocerca volvulus 0.0047 0.0043 0.0087
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0224 0.0411 0.0407
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.2883
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0043 0.0042
Loa Loa (eye worm) glycogen phosphorylase 0.0123 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0076 0.0104 0.0104
Brugia malayi Proteasome A-type and B-type family protein 0.0041 0.0031 0.003
Echinococcus granulosus calpain A 0.402 0.8266 0.8266
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0397 0.0768 0.2112
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Echinococcus multilocularis fibropellin Ia 0.0044 0.0037 0.0036
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Loa Loa (eye worm) hypothetical protein 0.2191 0.4481 0.4481
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0041 0.0031 0.0087
Trypanosoma brucei Calpain-like protein 2 0.0415 0.0806 0.1791
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Onchocerca volvulus 0.1542 0.3137 0.6461
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0041 0.0031 0.0027
Trypanosoma cruzi calmodulin, putative 0.0224 0.0411 0.0407
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0041 0.0031 0.0087
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0031 0.0027
Echinococcus granulosus neurocalcin 0.0224 0.0411 0.041
Brugia malayi fibroinase precursor 0.0397 0.0768 0.0767
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0041 0.0031 0.0061
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0013 0.0013
Echinococcus granulosus Proteasome subunit alpha type 7 0.0041 0.0031 0.003
Echinococcus multilocularis calcium uptake protein 1 0.0228 0.0418 0.0417
Giardia lamblia Alanyl dipeptidyl peptidase 0.0257 0.0478 0.1309
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Onchocerca volvulus 0.1542 0.3137 0.6461
Loa Loa (eye worm) prolyl oligopeptidase 0.0257 0.0478 0.0478
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0152 0.0151
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0013 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0248 0.0247
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0023 0.0019
Loa Loa (eye worm) programmed cell death protein 6 0.0228 0.0418 0.0418
Schistosoma mansoni calmodulin 0.0224 0.0411 0.041
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0233 0.0634
Toxoplasma gondii cathepsin CPC1 0.0397 0.0768 0.1707
Echinococcus multilocularis programmed cell death protein 0.0232 0.0426 0.0425
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0041 0.0031 0.0087
Echinococcus multilocularis calpain A 0.402 0.8266 0.8266
Onchocerca volvulus 0.0187 0.0333 0.0683
Trypanosoma cruzi oligopeptidase b 0.0889 0.1787 0.1784
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0034 0.0017 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Giardia lamblia Cathepsin L-like protease 0.0397 0.0768 0.2112
Brugia malayi Calcium binding EGF domain containing protein 0.0044 0.0037 0.0036
Trypanosoma brucei proteasome beta 7 subunit 0.0041 0.0031 0.0061
Echinococcus multilocularis chromatin regulatory protein sir2 0.0125 0.0206 0.0205
Leishmania major sir2-family protein-like protein 0.0032 0.0013 0.0021
Loa Loa (eye worm) proteasome subunit beta type 1 0.0145 0.0247 0.0247
Echinococcus multilocularis calbindin 32 0.0228 0.0418 0.0417
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0224 0.0411 0.0407
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0257 0.0478 0.1058
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1542 0.3137 0.3137
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2191 0.4481 0.448
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0241 0.1322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0253 0.047 0.0466
Loa Loa (eye worm) hypothetical protein 0.0257 0.0478 0.0478
Echinococcus granulosus Regulator of G protein signaling 20 0.0045 0.0039 0.0038
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0039 0.0038
Mycobacterium leprae probable zinc metalloprotease 0.0101 0.0155 0.084
Plasmodium vivax calpain, putative 0.142 0.2885 0.9195
Mycobacterium tuberculosis Long conserved protein 0.0291 0.0548 0.1374
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0045 0.0039 0.0039
Leishmania major C-8 sterol isomerase-like protein 0.036 0.0691 0.1535
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Onchocerca volvulus Peroxidase homolog 0.0499 0.0979 0.2014
Trypanosoma brucei mitochondrial calcium uptake 1 0.0224 0.0411 0.0909
Echinococcus multilocularis acylamino acid releasing enzyme 0.0257 0.0478 0.0477
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0056 0.0055
Schistosoma mansoni neuronal calcium sensor 0.0224 0.0411 0.041
Giardia lamblia Cathepsin B precursor 0.0397 0.0768 0.2112
Plasmodium vivax vivapain-2 0.1542 0.3137 1
Echinococcus granulosus tissue type plasminogen activator 0.007 0.0092 0.0091
Leishmania major proteasome beta-1 subunit, putative 0.0041 0.0031 0.0061
Loa Loa (eye worm) Notch2 0.0044 0.0037 0.0037
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0041 0.0031 0.0061
Echinococcus multilocularis calpain 7 (C02 family) 0.142 0.2885 0.2885
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0013 0.003
Onchocerca volvulus 0.0201 0.0363 0.0745
Onchocerca volvulus 0.1542 0.3137 0.6461
Brugia malayi EGF-like domain containing protein 0.0044 0.0037 0.0036
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0034 0.0017 0.0013
Leishmania major calcineurin B subunit, putative 0.0224 0.0411 0.0909
Echinococcus granulosus apoptotic protease activating factor 1 0.0221 0.0403 0.0402
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0013 0.0012
Leishmania major silent information regulator 2, putative 0.0125 0.0206 0.0451
Onchocerca volvulus Legumain homolog 0.0147 0.0251 0.0514
Brugia malayi cathepsin Z-like cysteine proteinase 0.0397 0.0768 0.0767
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0333 0.0332
Trypanosoma brucei prolyl endopeptidase 0.2191 0.4481 1
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0041 0.0031 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Plasmodium falciparum cysteine repeat modular protein 1 0.007 0.0092 0.0281
Echinococcus multilocularis protein jagged 1 0.0044 0.0037 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0397 0.0768 0.2112
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.2883
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0397 0.0768 0.2112
Leishmania major oligopeptidase b 0.0889 0.1787 0.3983
Leishmania major calmodulin-like protein 0.0224 0.0411 0.0909
Schistosoma mansoni notch 0.0044 0.0037 0.0036
Schistosoma mansoni cpg binding protein 0.0061 0.0073 0.0072
Echinococcus multilocularis cathepsin b 0.4858 1 1
Loa Loa (eye worm) hypothetical protein 0.0201 0.0363 0.0363
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0041 0.0031 0.0061
Echinococcus granulosus prolyl endopeptidase 0.2191 0.4481 0.448
Leishmania major hypothetical protein, conserved 0.0415 0.0806 0.1791
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0251 0.0682
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0139 0.0233 0.0232
Brugia malayi Histone deacetylase family protein 0.01 0.0152 0.0151
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.0336 0.0335
Brugia malayi Cathepsin L-like precursor 0.1542 0.3137 0.3137
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0039 0.0097
Echinococcus multilocularis histone deacetylase 7 0.01 0.0152 0.0151
Echinococcus multilocularis enteropeptidase 0.0201 0.0363 0.0362
Echinococcus granulosus histone lysine methyltransferase setb 0.0103 0.016 0.0159
Mycobacterium leprae Conserved hypothetical protein 0.0291 0.0548 0.3043
Plasmodium falciparum serine repeat antigen 3 0.0397 0.0768 0.2439
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0013 0.0026
Giardia lamblia Proteasome subunit beta type 1 0.0145 0.0247 0.0671
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0051 0.0052 0.0051
Mycobacterium leprae conserved hypothetical protein 0.0108 0.017 0.0925
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Entamoeba histolytica cysteine protease, putative 0.0397 0.0768 0.2439
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0206 0.0205
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0036
Trichomonas vaginalis calmodulin, putative 0.0224 0.0411 0.1124
Brugia malayi Thioredoxin family protein 0.0291 0.0548 0.0547
Trichomonas vaginalis glycogen phosphorylase, putative 0.0123 0.02 0.0543
Echinococcus multilocularis neural cadherin 0.0044 0.0037 0.0036
Loa Loa (eye worm) calmodulin-like protein 0.0224 0.0411 0.0411
Echinococcus granulosus proteasome subunit beta t family 0.0041 0.0031 0.003
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0224 0.0411 0.0909
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0397 0.0768 0.0768
Entamoeba histolytica glycogen phosphorylase, putative 0.0123 0.02 0.0627
Loa Loa (eye worm) animal heme peroxidase 0.0499 0.0979 0.0979
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0039 0.0038
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0415 0.0806 0.2215
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0142 0.0241 0.024
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0041 0.0031 0.0061
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0041 0.0031 0.0061
Brugia malayi hypothetical protein 0.0045 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1777 0.3623 1
Leishmania major proteasome alpha 7 subunit, putative 0.0041 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0101 0.0155 0.0155
Echinococcus granulosus calpain 0.142 0.2885 0.2885
Schistosoma mansoni cpg binding protein 0.0065 0.008 0.0079
Schistosoma mansoni slit 0.0044 0.0037 0.0036
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0386 0.0745 0.0744
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0013 0.0021
Entamoeba histolytica calpain family cysteine protease, putative 0.0415 0.0806 0.2559
Trichomonas vaginalis conserved hypothetical protein 0.0224 0.0411 0.1124
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0092 0.0137 0.0136
Onchocerca volvulus 0.0107 0.0167 0.0342
Echinococcus granulosus protein jagged 2 0.0044 0.0037 0.0036
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0041 0.0031 0.0087
Plasmodium vivax histone deacetylase 2, putative 0.01 0.0152 0.0474
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.0806 0.0802
Loa Loa (eye worm) hypothetical protein 0.0026 0.0001 0.0001
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0139 0.0233 0.0232
Brugia malayi calpain 7 0.142 0.2885 0.2885
Onchocerca volvulus 0.0224 0.0411 0.0844
Loa Loa (eye worm) cysteine protease 0.1542 0.3137 0.3137
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0041 0.0031 0.0087
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1934 0.395 1
Schistosoma mansoni reticulocalbin 0.0224 0.0411 0.041
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0415 0.0806 0.2215
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.013 0.0348
Trypanosoma cruzi centrin, putative 0.0232 0.0426 0.0422
Loa Loa (eye worm) hypothetical protein 0.0173 0.0305 0.0305
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0092 0.0137 0.0133
Toxoplasma gondii proteasome subunit alpha type, putative 0.0041 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0103 0.016 0.016
Brugia malayi Cathepsin L-like precursor 0.1542 0.3137 0.3137
Giardia lamblia Cysteine protease 0.0397 0.0768 0.2112
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.016 0.0159
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0041 0.0031 0.0087
Trypanosoma cruzi 20S proteasome subunit 0.0092 0.0137 0.0133
Toxoplasma gondii heat shock protein hslv, putative 0.0041 0.0031 0.0061
Leishmania major hypothetical protein, unknown function 0.0415 0.0806 0.1791
Giardia lamblia Cathepsin B precursor 0.0397 0.0768 0.2112
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0031 0.0061
Brugia malayi Cathepsin L-like cysteine proteinase 0.1078 0.2177 0.2176
Plasmodium vivax proteasome subunit beta type-3, putative 0.0041 0.0031 0.0087
Echinococcus multilocularis calumenin 0.0228 0.0418 0.0417
Schistosoma mansoni calpain C (C02 family) 0.142 0.2885 0.2885
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Trichomonas vaginalis conserved hypothetical protein 0.0397 0.0768 0.2112
Brugia malayi EGF-like domain containing protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0075 0.0101 0.0101
Trypanosoma brucei protein I/6 0.0224 0.0411 0.0909
Onchocerca volvulus 0.0045 0.004 0.0081
Loa Loa (eye worm) histone deacetylase 3 0.0089 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0108 0.017 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0039 0.0097
Toxoplasma gondii centrin 0.0224 0.0411 0.0909
Echinococcus multilocularis regulator of G protein signaling 0.0045 0.0039 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0248 0.0247
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0224 0.0411 0.0407
Loa Loa (eye worm) hypothetical protein 0.1078 0.2177 0.2177
Onchocerca volvulus 0.0045 0.004 0.0081
Schistosoma mansoni cathepsin F (C01 family) 0.1542 0.3137 0.3137
Onchocerca volvulus 0.1542 0.3137 0.6461
Brugia malayi calpain family protein 1 0.3792 0.7795 0.7794
Toxoplasma gondii PAN/Apple domain-containing protein 0.0045 0.004 0.0082
Schistosoma mansoni hypothetical protein 0.0058 0.0066 0.0065
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Brugia malayi Cytochrome P450 family protein 0.0037 0.0023 0.0022
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0039 0.0038
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1675 0.3412 0.3411
Loa Loa (eye worm) hypothetical protein 0.0464 0.0907 0.0907
Echinococcus granulosus notch 0.0044 0.0037 0.0036
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0251 0.0682
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0092 0.0137 0.0425
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0017 0.0037
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0041 0.0031 0.0027
Schistosoma mansoni caspase-3 (C14 family) 0.0386 0.0745 0.0744
Brugia malayi Blistered cuticle protein 3 0.0499 0.0979 0.0978
Loa Loa (eye worm) hypothetical protein 0.0063 0.0077 0.0077
Echinococcus multilocularis neurogenic locus notch protein 4 0.0044 0.0037 0.0036
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0092 0.0137 0.0136
Giardia lamblia Glycogen phosphorylase 0.0123 0.02 0.0543
Brugia malayi Cathepsin L-like precursor 0.1078 0.2177 0.2176
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0041 0.0031 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0013 0.0026
Brugia malayi prolyl oligopeptidase family protein 0.0257 0.0478 0.0477
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0039 0.0038
Toxoplasma gondii peptidase family M13 protein 0.0101 0.0155 0.0339
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0041 0.0031 0.0031
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0041 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Onchocerca volvulus 0.007 0.0092 0.0187
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Brugia malayi Proteasome A-type and B-type family protein 0.0041 0.0031 0.003
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0125 0.0206 0.0205
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0397 0.0768 0.0767
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0253 0.047 0.1177
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0397 0.0768 0.2112
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0001 0.0001
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0031 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0397 0.0768 0.0767
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4858 1 1
Echinococcus granulosus calpain A 0.142 0.2885 0.2885
Giardia lamblia Proteasome subunit beta type 2 0.0092 0.0137 0.0368
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0093 0.0092
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0039 0.0038
Brugia malayi notch-like transmembrane receptor 0.0044 0.0037 0.0036
Entamoeba histolytica grainin, putative 0.0228 0.0418 0.1323
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1542 0.3137 0.3137
Loa Loa (eye worm) peptidase C13 family protein 0.0147 0.0251 0.0251
Toxoplasma gondii aspartyl protease ASP3 0.0189 0.0338 0.0747
Loa Loa (eye worm) proteasome subunit beta type 2 0.0092 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.0305 0.0832
Trypanosoma cruzi C-8 sterol isomerase, putative 0.036 0.0691 0.0687
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Trypanosoma brucei Calpain-like protein CALP1.3 0.0415 0.0806 0.1791
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Echinococcus multilocularis neuronal calcium sensor 0.0224 0.0411 0.041
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.004 0.004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0861 0.1729 0.1728
Trypanosoma brucei calpain-like protein, putative 0.142 0.2885 0.6436
Trichomonas vaginalis calcium binding protein, putative 0.0232 0.0426 0.1166
Schistosoma mansoni histone deacetylase 1 2 3 0.0043 0.0035 0.0034
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0004 0.0003
Leishmania major protein kinase, putative 0.0224 0.0411 0.0909
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0228 0.0418 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1078 0.2177 0.6004
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0015 0.0014
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0013 0.0021
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0206 0.0202
Echinococcus multilocularis proteasome subunit beta type 6 0.0041 0.0031 0.003
Brugia malayi cathepsin L precursor 0.0397 0.0768 0.0767
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0415 0.0806 0.2215
Brugia malayi Cytochrome P450 family protein 0.0037 0.0023 0.0022
Schistosoma mansoni hypothetical protein 0.0342 0.0655 0.0654
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.017 0.046
Brugia malayi cathepsin Z-like cysteine proteinase 0.0397 0.0768 0.0767
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0397 0.0768 0.0768
Echinococcus multilocularis dnaJ subfamily B 0.0471 0.0922 0.0921
Loa Loa (eye worm) hypothetical protein 0.0397 0.0768 0.0768
Toxoplasma gondii centrin, putative 0.0224 0.0411 0.0909
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0041 0.0031 0.0031
Echinococcus granulosus microtubule associated protein 2 0.1591 0.3239 0.3238
Giardia lamblia Hypothetical protein 0.0125 0.0206 0.0558
Brugia malayi EGF-like domain containing protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.036 0.0691 0.0691
Leishmania major proteasome alpha 7 subunit, putative 0.0041 0.0031 0.0061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0257 0.0478 0.0477
Schistosoma mansoni calpain (C02 family) 0.142 0.2885 0.2885
Leishmania major histone deacetylase, putative 0.01 0.0152 0.0332
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0013 0.0012
Schistosoma mansoni septate junction protein 0.0044 0.0037 0.0036
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Echinococcus multilocularis cathepsin L cysteine protease 0.1542 0.3137 0.3137
Brugia malayi proteasome subunit beta type 1 0.0145 0.0247 0.0246
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0034 0.0017 0.003
Echinococcus granulosus glycogen phosphorylase 0.0123 0.02 0.0199
Plasmodium vivax vivapain-2 0.1542 0.3137 1
Echinococcus multilocularis neurogenic locus protein delta 0.0044 0.0037 0.0036
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0045 0.0039 0.0038
Schistosoma mansoni gamma-secretase subunit aph-1 0.0276 0.0518 0.0517
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0041 0.0031 0.003
Loa Loa (eye worm) histone deacetylase 1 0.0089 0.013 0.013
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0224 0.0411 0.1298
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0041 0.0031 0.003
Plasmodium vivax proteasome subunit beta type-1, putative 0.0145 0.0247 0.0776
Brugia malayi proteasome subunit beta type 3 0.0041 0.0031 0.003
Onchocerca volvulus 0.0045 0.004 0.0081
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0101 0.0101
Plasmodium vivax proteasome subunit beta type-5, putative 0.0253 0.047 0.1487
Trypanosoma cruzi Aph-1 protein, putative 0.0108 0.0169 0.0165
Leishmania major cathepsin L-like protease 0.1652 0.3365 0.7507
Schistosoma mansoni hypothetical protein 0.0033 0.0015 0.0014
Onchocerca volvulus 0.0103 0.016 0.0327
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0031 0.0027
Trypanosoma cruzi I/6 autoantigen, putative 0.0224 0.0411 0.0407
Brugia malayi Cadherin domain containing protein 0.0044 0.0037 0.0036
Echinococcus granulosus cathepsin l1 0.1542 0.3137 0.3137
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2191 0.4481 1
Schistosoma mansoni calpain-2 (C02 family) 0.0415 0.0806 0.0805
Toxoplasma gondii microneme protein, putative 0.0045 0.004 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0397 0.0768 0.2112
Schistosoma mansoni cathepsin D (A01 family) 0.0217 0.0395 0.0395
Entamoeba histolytica glycogen phosphorylase, putative 0.0123 0.02 0.0627
Trichomonas vaginalis calmodulin, putative 0.0232 0.0426 0.1166
Brugia malayi Cathepsin L-like precursor 0.1542 0.3137 0.3137
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0006 0.0006
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Trypanosoma brucei proteasome alpha 7 subunit 0.0041 0.0031 0.0061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0257 0.0478 0.0477
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0039 0.0038
Brugia malayi gamma-secretase subunit aph-1 0.0276 0.0518 0.0517
Echinococcus granulosus cpg binding protein 0.0065 0.008 0.0079
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0006 0.0006
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0031 0.0061
Brugia malayi ERG2 and Sigma1 receptor like protein 0.036 0.0691 0.069
Echinococcus granulosus histone deacetylase 3 0.0089 0.013 0.0129
Trypanosoma brucei histone deacetylase 2 0.0043 0.0035 0.0069
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0889 0.1787 0.1784
Toxoplasma gondii PAN domain-containing protein 0.0045 0.004 0.0082
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0257 0.0478 0.1058
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Echinococcus granulosus acylamino acid releasing enzyme 0.0257 0.0478 0.0477
Echinococcus granulosus calpain 5 0.142 0.2885 0.2885
Brugia malayi Cathepsin L-like precursor 0.1542 0.3137 0.3137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0861 0.1729 0.3853
Trypanosoma brucei centrin, putative 0.0224 0.0411 0.0909
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.0012 0.0011
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0051 0.0052 0.0051
Leishmania major hypothetical protein, conserved 0.0228 0.0418 0.0926
Trichomonas vaginalis conserved hypothetical protein 0.0224 0.0411 0.1124
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0006 0.0006
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0253 0.047 0.2606
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0041 0.0031 0.0027
Schistosoma mansoni ets-related 0.0216 0.0392 0.0392
Echinococcus granulosus flap endonuclease 1 0.0028 0.0004 0.0003
Echinococcus multilocularis histone deacetylase 1 0.0089 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0224 0.0411 0.1298
Loa Loa (eye worm) hypothetical protein 0.0076 0.0104 0.0104
Entamoeba histolytica cysteine proteinase 1, putative 0.0861 0.1729 0.5504
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.0806 0.0802
Plasmodium vivax hypothetical protein, conserved 0.0228 0.0418 0.1323
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0036
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0253 0.047 0.1487
Loa Loa (eye worm) hypothetical protein 0.005 0.005 0.005
Echinococcus multilocularis caspase 3 0.0212 0.0386 0.0385
Trichomonas vaginalis centrin, putative 0.0224 0.0411 0.1124
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0397 0.0768 0.0768
Plasmodium vivax vivapain-1 0.0861 0.1729 0.5504
Mycobacterium ulcerans hypothetical protein 0.0108 0.017 0.0925
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0889 0.1787 1
Entamoeba histolytica cysteine protease, putative 0.0397 0.0768 0.2439
Brugia malayi A-kinase anchor protein 10, precursor 0.0045 0.0039 0.0038
Echinococcus granulosus endothelin converting enzyme 1 0.0101 0.0155 0.0154
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.0336 0.0335
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0041 0.0031 0.0027
Brugia malayi hypothetical protein 0.0201 0.0363 0.0362
Schistosoma mansoni notch 0.0044 0.0037 0.0036
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0464 0.0907 0.0906
Entamoeba histolytica prolyl oligopeptidase family protein 0.0257 0.0478 0.1512
Echinococcus multilocularis caspase 0.0386 0.0745 0.0744
Trypanosoma brucei calmodulin, putative 0.0228 0.0418 0.0926
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0233 0.0634
Echinococcus granulosus enteropeptidase 0.0201 0.0363 0.0362
Schistosoma mansoni hypothetical protein 0.0471 0.0922 0.0921
Echinococcus multilocularis Mastin 0.0201 0.0363 0.0362
Leishmania major calpain family cysteine protease-like protein 0.0415 0.0806 0.1791
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Onchocerca volvulus 0.0044 0.0037 0.0074
Trypanosoma cruzi I/6 autoantigen, putative 0.0224 0.0411 0.0407
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0253 0.047 0.1288
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.0031 0.003
Onchocerca volvulus Peroxidase homolog 0.0499 0.0979 0.2014
Schistosoma mansoni intermediate filament proteins 0.0026 0.0001 0.0000090515
Entamoeba histolytica cysteine protease, putative 0.0397 0.0768 0.2439
Loa Loa (eye worm) blistered cuticle protein 3 0.0499 0.0979 0.0979
Plasmodium vivax hypothetical protein, conserved 0.0257 0.0478 0.1512
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Trypanosoma brucei cysteine peptidase, putative 0.0415 0.0806 0.1791
Mycobacterium ulcerans putative transglutaminase-like protein 0.0291 0.0548 0.3043
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0251 0.0682
Echinococcus granulosus glycoprotein Antigen 5 0.0201 0.0363 0.0362
Onchocerca volvulus Prolyl endopeptidase homolog 0.2191 0.4481 0.9228
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0103 0.016 0.0159
Brugia malayi Pre-SET motif family protein 0.0711 0.1418 0.1417
Mycobacterium tuberculosis Conserved hypothetical protein 0.0291 0.0548 0.1374
Leishmania major proteasome alpha 2 subunit, putative 0.0041 0.0031 0.0061
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0354 0.0679 0.1508
Trypanosoma brucei metacaspase MCA3 0.0173 0.0305 0.0673
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0206 0.0205
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0041 0.0031 0.003
Toxoplasma gondii PAN domain-containing protein 0.0045 0.004 0.0082
Loa Loa (eye worm) hypothetical protein 0.2372 0.4856 0.4856
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.004
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Echinococcus granulosus expressed protein 0.0871 0.1748 0.1747
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Onchocerca volvulus 0.0044 0.0037 0.0074
Echinococcus multilocularis proteasome subunit alpha type 6 0.0041 0.0031 0.003
Trichomonas vaginalis calmodulin, putative 0.0228 0.0418 0.1145
Loa Loa (eye worm) hypothetical protein 0.0034 0.0017 0.0017
Onchocerca volvulus 0.0108 0.017 0.0349
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.017 0.0418
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Echinococcus granulosus GPI anchor transamidase 0.0034 0.0017 0.0016
Leishmania major calmodulin, putative 0.0224 0.0411 0.0909
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.0305 0.0832
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0041 0.0031 0.0087
Echinococcus multilocularis protein jagged 2 0.0044 0.0037 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0039 0.0038
Echinococcus granulosus peroxidasin 0.0499 0.0979 0.0978
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0187 0.0333 0.0332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Trichomonas vaginalis calcineurin B subunit, putative 0.0228 0.0418 0.1145
Brugia malayi Peroxidasin 0.0499 0.0979 0.0978
Entamoeba histolytica hypothetical protein, conserved 0.0228 0.0418 0.1323
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Schistosoma mansoni cathepsin s 0.0464 0.0907 0.0906
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.017 0.0418
Trypanosoma cruzi conserved protein 0.0415 0.0806 0.0802
Giardia lamblia Cathepsin L precursor 0.0397 0.0768 0.2112
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0031 0.0027
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0397 0.0768 0.2439
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0142 0.0241 0.024
Schistosoma mansoni caspase-7 (C14 family) 0.0394 0.0762 0.0761
Entamoeba histolytica cysteine protease, putative 0.1542 0.3137 1
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0152 0.0149
Echinococcus granulosus caspase 3 0.0212 0.0386 0.0385
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.017 0.017
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0397 0.0768 0.2439
Schistosoma mansoni cathepsin F (C01 family) 0.1078 0.2177 0.2176
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Trypanosoma brucei Aph-1 protein, putative 0.0108 0.0169 0.0369
Schistosoma mansoni hypothetical protein 0.0342 0.0655 0.0654
Schistosoma mansoni calpain-7 (C02 family) 0.1423 0.2892 0.2891
Schistosoma mansoni centrin 0.0224 0.0411 0.041
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0013 0.003
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0013 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0092 0.0088
Schistosoma mansoni hypothetical protein 0.0201 0.0363 0.0362
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.013 0.0348
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4017 0.8259 0.8259
Loa Loa (eye worm) RGS-3 protein 0.0045 0.0039 0.0039
Onchocerca volvulus 0.0061 0.0073 0.0148
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0045 0.0039 0.0038
Trypanosoma cruzi metacaspase 5, putative 0.0173 0.0305 0.0301
Echinococcus multilocularis expressed protein 0.0871 0.1748 0.1747
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Giardia lamblia Histone deacetylase 0.0089 0.013 0.0348
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0041 0.0031 0.003
Brugia malayi Protein kinase domain containing protein 0.007 0.0092 0.0091
Loa Loa (eye worm) sirtuin 4 0.0032 0.0013 0.0013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4858 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0397 0.0768 0.0767
Toxoplasma gondii cathepsin B 0.1777 0.3623 0.8085
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0397 0.0768 0.2112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Loa Loa (eye worm) hypothetical protein 0.0397 0.0768 0.0768
Mycobacterium ulcerans transglutaminase family protein 0.0291 0.0548 0.3043
Trypanosoma cruzi calmodulin, putative 0.0224 0.0411 0.0407
Brugia malayi calcium-binding protein 0.0224 0.0411 0.041
Plasmodium vivax unspecified product 0.0861 0.1729 0.5504
Giardia lamblia Cathepsin B precursor 0.1777 0.3623 1
Entamoeba histolytica grainin 2 0.0232 0.0426 0.1346
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0013 0.0026
Toxoplasma gondii microneme protein MIC17C 0.0045 0.004 0.0082
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0041 0.0031 0.0061
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0461 0.0461
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0041 0.0031 0.0031
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0013 0.0012
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0178 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0041 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0397 0.0768 0.2112
Leishmania major histone deacetylase, putative 0.01 0.0152 0.0332
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0041 0.0031 0.003
Brugia malayi Peptidase C13 family protein 0.0147 0.0251 0.025
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.0251 0.025
Brugia malayi Papain family cysteine protease containing protein 0.0397 0.0768 0.0767
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0415 0.0806 0.2215
Leishmania major histone deacetylase, putative 0.0089 0.013 0.0281
Giardia lamblia Cysteine protease 0.0397 0.0768 0.2112
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1542 0.3137 0.8658
Trypanosoma brucei antigen, putative 0.142 0.2885 0.6436
Schistosoma mansoni reticulocalbin 0.0228 0.0418 0.0417
Trichomonas vaginalis calcium binding protein, putative 0.0224 0.0411 0.1124
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0056 0.0055
Plasmodium vivax histone deacetylase 1, putative 0.0089 0.013 0.0402
Loa Loa (eye worm) hypothetical protein 0.0053 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0201 0.0363 0.0363
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.004 0.004
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0006 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1542 0.3137 0.8658
Entamoeba histolytica calcium binding family protein 0.0224 0.0411 0.1298
Trypanosoma brucei calpain-like protein, putative 0.142 0.2885 0.6436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0039
Trypanosoma cruzi kinesin, putative 0.1005 0.2026 0.2023
Trypanosoma cruzi cruzipain precursor, putative 0.0464 0.0907 0.0904
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0092 0.0137 0.0297
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0201 0.0363 0.0362
Echinococcus multilocularis survival motor neuron protein 1 0.0282 0.053 0.053
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0043 0.0087
Echinococcus multilocularis histone deacetylase 0.01 0.0152 0.0151
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0206 0.0202
Toxoplasma gondii PAN domain-containing protein 0.0045 0.004 0.0082
Trypanosoma brucei calmodulin, putative 0.0224 0.0411 0.0909
Loa Loa (eye worm) hypothetical protein 0.0184 0.0327 0.0327
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0201 0.0363 0.0362
Mycobacterium ulcerans hypothetical protein 0.0291 0.0548 0.3043
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0041 0.0031 0.0087
Schistosoma mansoni neuronal calcium sensor 0.0224 0.0411 0.041
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.017 0.0169
Plasmodium falciparum serine repeat antigen 1 0.0397 0.0768 0.2439
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0041 0.0031 0.003
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0031 0.0061
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0415 0.0806 0.0805
Echinococcus granulosus protein jagged 1 0.0044 0.0037 0.0036
Trichomonas vaginalis calmodulin, putative 0.0224 0.0411 0.1124
Echinococcus granulosus EF hand domain containing family member A2 0.0228 0.0418 0.0417
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.004
Onchocerca volvulus Cathepsin L homolog 0.0397 0.0768 0.158
Giardia lamblia Cathepsin B precursor 0.0397 0.0768 0.2112
Plasmodium vivax proteasome subunit beta type-7, putative 0.0041 0.0031 0.0087
Onchocerca volvulus 0.005 0.005 0.0101
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0006 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.0305 0.0832
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0043 0.0042
Schistosoma mansoni cathepsin S (C01 family) 0.0397 0.0768 0.0767
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0125 0.0206 0.0205
Plasmodium falciparum cysteine proteinase falcipain 3 0.1542 0.3137 1
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0044 0.0037 0.0036
Entamoeba histolytica cysteine proteinase, putative 0.0861 0.1729 0.5504
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0023 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0397 0.0768 0.2112
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0397 0.0768 0.0767
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.016 0.0159
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.142 0.2885 0.2883
Toxoplasma gondii proteasome beta subunit 0.0041 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0047 0.0043 0.0043
Toxoplasma gondii histone deacetylase HDAC4 0.0043 0.0035 0.0069
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0053 0.0056 0.0128
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0101 0.0155 0.0154
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0039 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Echinococcus granulosus Dipeptidyl peptidase 9 0.0354 0.0679 0.0678
Schistosoma mansoni glycogen phosphorylase 0.0123 0.02 0.0199
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0241 0.1322
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.0013 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Giardia lamblia Cathepsin L-like protease 0.0397 0.0768 0.2112
Echinococcus multilocularis prolyl endopeptidase 0.2191 0.4481 0.448
Trypanosoma cruzi cruzipain precursor, putative 0.1652 0.3365 0.3362
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0415 0.0806 0.2215
Toxoplasma gondii cathepsin CPL 0.1542 0.3137 0.7
Plasmodium falciparum centrin-1 0.0224 0.0411 0.1298
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0013 0.0021
Plasmodium falciparum serine repeat antigen 5 0.0397 0.0768 0.2439
Trypanosoma brucei Calpain-like protein 1.1 0.0415 0.0806 0.1791
Brugia malayi EF hand family protein 0.0228 0.0418 0.0417
Schistosoma mansoni calmodulin 0.0224 0.0411 0.041
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.017 0.0167
Toxoplasma gondii proteasome subunit alpha1, putative 0.0041 0.0031 0.0061
Loa Loa (eye worm) fli-1 protein 0.0216 0.0392 0.0392
Echinococcus multilocularis EF hand domain containing family member A2 0.0228 0.0418 0.0417
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0173 0.0305 0.0673
Trypanosoma brucei caltractin, putative 0.0232 0.0426 0.0942
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0031 0.0061
Brugia malayi regulator of G-protein signaling rgs-7 0.0045 0.0039 0.0038
Trypanosoma cruzi metacaspase, putative 0.0173 0.0305 0.0301
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0889 0.1787 0.3983
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.4017 0.8259 0.8259
Brugia malayi proteasome subunit alpha type 1 0.0041 0.0031 0.003
Echinococcus granulosus cathepsin l1 0.1078 0.2177 0.2176
Onchocerca volvulus 0.0045 0.004 0.0081
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0013 0.003
Brugia malayi Cadherin domain containing protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.2787 0.5715 0.5715
Entamoeba histolytica calpain large subunit domain III containing protein 0.1005 0.2026 0.6453
Brugia malayi EGF-like domain containing protein 0.0044 0.0037 0.0036
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.013 0.0348
Echinococcus multilocularis neurogenic locus notch protein 0.0044 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0201 0.0363 0.0362
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1777 0.3623 0.8085
Echinococcus granulosus histone deacetylase 6 0.0106 0.0165 0.0164
Schistosoma mansoni glycogen phosphorylase 0.0123 0.02 0.0199
Trypanosoma brucei cysteine peptidase C (CPC) 0.1777 0.3623 0.8085
Toxoplasma gondii hypothetical protein 0.0415 0.0806 0.1791
Schistosoma mansoni mitochondrial solute carrier 0.0224 0.0411 0.041
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0041 0.0031 0.0087
Trypanosoma brucei C-8 sterol isomerase, putative 0.036 0.0691 0.1535
Plasmodium falciparum plasmepsin X 0.0189 0.0338 0.1067
Onchocerca volvulus Putative cubilin 0.0044 0.0037 0.0074
Trichomonas vaginalis calpain, putative 0.0415 0.0806 0.2215
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.004 0.004
Brugia malayi Delta serrate ligand family protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0145 0.0247 0.0243
Trypanosoma cruzi cysteine proteinase, putative 0.0861 0.1729 0.1726
Echinococcus multilocularis hypothetical protein 0.142 0.2885 0.2885
Echinococcus granulosus histone deacetylase 8 0.0043 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0464 0.0907 0.0907
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0041 0.0031 0.0087
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0397 0.0768 0.0767
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0013 0.003
Giardia lamblia Cathepsin L precursor 0.0397 0.0768 0.2112
Schistosoma mansoni cathepsin C 0.0397 0.0768 0.0767
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0043 0.0042
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0041 0.0031 0.0061
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.017 0.0418
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0354 0.0679 0.1508
Brugia malayi Animal haem peroxidase family protein 0.0499 0.0979 0.0978
Giardia lamblia Hypothetical protein 0.0397 0.0768 0.2112
Echinococcus granulosus histone deacetylase 1 0.0089 0.013 0.0129
Echinococcus multilocularis cysteine protease 0.1542 0.3137 0.3137
Loa Loa (eye worm) hypothetical protein 0.0415 0.0806 0.0806
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0397 0.0768 0.2439
Plasmodium falciparum GPI-anchor transamidase, putative 0.0034 0.0017 0.0042
Plasmodium falciparum calpain 0.0415 0.0806 0.2559
Loa Loa (eye worm) hypothetical protein 0.1078 0.2177 0.2177
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Trichomonas vaginalis calmodulin, putative 0.0224 0.0411 0.1124
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0036
Leishmania major proteasome beta 2 subunit, putative 0.0092 0.0137 0.0297
Mycobacterium ulcerans proteasome PrcB 0.0253 0.047 0.2606
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0173 0.0305 0.0673
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0889 0.1787 0.3983
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1542 0.3137 0.3137
Echinococcus multilocularis proteasome subunit alpha type 2 0.0041 0.0031 0.003
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0251 0.0682
Trypanosoma cruzi metacaspase, putative 0.0173 0.0305 0.0301
Echinococcus granulosus delta-like protein 1 0.0044 0.0037 0.0036
Echinococcus multilocularis GPI anchor transamidase 0.0034 0.0017 0.0016
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0004 0.0004
Trypanosoma brucei metacaspase MCA2 0.0173 0.0305 0.0673
Plasmodium falciparum histone deacetylase 2 0.01 0.0152 0.0474
Loa Loa (eye worm) animal heme peroxidase 0.0499 0.0979 0.0979
Entamoeba histolytica hypothetical protein 0.0045 0.0039 0.0112
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0041 0.0031 0.0087
Echinococcus granulosus calbindin 32 0.0228 0.0418 0.0417
Trypanosoma cruzi cysteine peptidase, putative 0.1542 0.3137 0.3135
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0073 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.6436
Entamoeba histolytica cysteine proteinase 2 0.0861 0.1729 0.5504
Giardia lamblia Cathepsin L precursor 0.0397 0.0768 0.2112
Plasmodium vivax unspecified product 0.0464 0.0907 0.2882
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0039 0.0038
Onchocerca volvulus Neurogenic locus notch homolog 0.0044 0.0038 0.0075
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0039 0.0038
Entamoeba histolytica histone deacetylase, putative 0.0089 0.013 0.0402
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Brugia malayi histone deacetylase 1 (HD1) 0.0089 0.013 0.0129
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0092 0.0137 0.0136
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0041 0.0031 0.0061
Giardia lamblia Hypothetical protein 0.0228 0.0418 0.1145
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0605 0.1199 0.1198
Plasmodium vivax proteasome subunit beta type-6, putative 0.0041 0.0031 0.0087
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Brugia malayi Papain family cysteine protease containing protein 0.0861 0.1729 0.1728
Schistosoma mansoni notch 0.0044 0.0037 0.0036
Plasmodium vivax aspartyl protease, putative 0.0189 0.0338 0.1067
Echinococcus multilocularis calmodulin 0.0224 0.0411 0.041
Brugia malayi Flap endonuclease-1 0.0028 0.0004 0.0003
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0173 0.0305 0.0304
Schistosoma mansoni z-protein (S1r protein) 0.0045 0.0039 0.0038
Brugia malayi proteasome subunit alpha type 3 0.0041 0.0031 0.003
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0145 0.0247 0.0243
Trypanosoma brucei Calpain-like protein 1.2 0.0415 0.0806 0.1791
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0041 0.0031 0.0061
Loa Loa (eye worm) calpain family protein 1 0.2787 0.5715 0.5715
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1777 0.3623 0.3621
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0041 0.0031 0.003
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0031 0.0061
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0041 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0075 0.0101 0.0101
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.017 0.0418
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0041 0.0031 0.003
Brugia malayi MH2 domain containing protein 0.0249 0.0461 0.046
Schistosoma mansoni notch 0.0044 0.0038 0.0037
Plasmodium falciparum peptidase, putative 0.0257 0.0478 0.1512
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1188 0.2404 0.2401
Trypanosoma cruzi calpain cysteine peptidase, putative 0.142 0.2885 0.2883
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0103 0.016 0.0349
Trichomonas vaginalis esterase, putative 0.0108 0.017 0.046
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0031 0.0075
Onchocerca volvulus Chorion peroxidase homolog 0.0499 0.0979 0.2014
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.017 0.0418
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0041 0.0031 0.0087
Giardia lamblia Cysteine protease 0.0397 0.0768 0.2112
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0041 0.0031 0.0142
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3792 0.7795 0.7794
Trypanosoma brucei histone deacetylase 4 0.01 0.0152 0.0332
Echinococcus granulosus EF HAND 1 calcium binding site 0.0224 0.0411 0.041
Onchocerca volvulus 0.0221 0.0403 0.0829
Echinococcus multilocularis histone deacetylase 6 0.01 0.0152 0.0151
Loa Loa (eye worm) hypothetical protein 0.0107 0.0167 0.0167
Onchocerca volvulus 0.0201 0.0363 0.0745
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.0241 0.024
Echinococcus multilocularis caspase 2 0.0394 0.0762 0.0761
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.013 0.0348
Loa Loa (eye worm) hypothetical protein 0.0061 0.0072 0.0072
Plasmodium falciparum plasmepsin IX 0.0189 0.0338 0.1067
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0461 0.0461
Loa Loa (eye worm) histone deacetylase 11 0.0043 0.0035 0.0035
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0041 0.0031 0.0087
Onchocerca volvulus Deterin homolog 0.0187 0.0333 0.0683
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0145 0.0247 0.0543
Loa Loa (eye worm) hypothetical protein 0.0282 0.053 0.053
Onchocerca volvulus Notchless protein homolog 0.0041 0.0031 0.0062
Brugia malayi mbt repeat family protein 0.0047 0.0043 0.0042
Mycobacterium ulcerans proteasome PrcA 0.0041 0.0031 0.0142
Schistosoma mansoni hypothetical protein 0.0288 0.0543 0.0542
Brugia malayi Pre-SET motif family protein 0.0103 0.016 0.0159
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0201 0.0363 0.0362
Onchocerca volvulus 0.0224 0.0411 0.0844
Mycobacterium leprae Probable lipase LipE 0.0108 0.017 0.0925
Onchocerca volvulus 0.1542 0.3137 0.6461
Toxoplasma gondii subtilisin SUB12 0.0045 0.004 0.0082
Brugia malayi Cytochrome P450 family protein 0.0061 0.0073 0.0072
Trypanosoma brucei metacaspase 0.0173 0.0305 0.0673
Echinococcus granulosus Proteasome subunit alpha beta 0.0041 0.0031 0.003
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0206 0.0558
Brugia malayi EGF-like domain containing protein 0.0044 0.0037 0.0036
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0397 0.0768 0.2439
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0041 0.0031 0.0075
Brugia malayi 20S proteasome alpha5 subunit 0.0041 0.0031 0.003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0397 0.0768 0.0767
Leishmania major i/6 autoantigen-like protein 0.0224 0.0411 0.0909
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.017 0.0167
Onchocerca volvulus 0.0045 0.004 0.0081
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0041 0.0031 0.0061
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0257 0.0478 0.1309
Trypanosoma brucei hypothetical protein 0.0415 0.0806 0.1791
Toxoplasma gondii microneme protein MIC17B 0.0045 0.004 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0103 0.016 0.0159
Echinococcus granulosus calmodulin 0.0224 0.0411 0.041
Echinococcus multilocularis cathepsin L 0.0397 0.0768 0.0767
Loa Loa (eye worm) proteasome subunit beta type 3 0.0041 0.0031 0.0031
Leishmania major cysteine peptidase A (CPA) 0.1542 0.3137 0.7
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4858 1 1
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0041 0.0031 0.003
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.013 0.0348
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0397 0.0768 0.2439
Echinococcus granulosus tumor protein p63 0.0729 0.1455 0.1455
Plasmodium falciparum metacaspase 1 0.0173 0.0305 0.0961
Echinococcus granulosus neurogenic locus notch protein 4 0.0044 0.0037 0.0036
Echinococcus granulosus cathepsin L 0.0861 0.1729 0.1728
Trichomonas vaginalis calmodulin, putative 0.0224 0.0411 0.1124
Toxoplasma gondii aldehyde dehydrogenase 0.0142 0.0241 0.053
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0889 0.1787 0.1784
Plasmodium vivax hypothetical protein, conserved 0.0108 0.017 0.0532
Echinococcus multilocularis tumor protein p63 0.0729 0.1455 0.1455
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0415 0.0806 0.0802
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0605 0.1199 0.2468
Echinococcus granulosus caspase 0.0386 0.0745 0.0744
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0041 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0108 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0187 0.0333 0.0333
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0036
Trypanosoma brucei Metacaspase-4 0.0173 0.0305 0.0673
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0041 0.0031 0.0031
Giardia lamblia 20S proteasome alpha subunit 7 0.0041 0.0031 0.0075
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Echinococcus multilocularis EF hand domain containing family member A2 0.0224 0.0411 0.041
Toxoplasma gondii cathepsin CPC2 0.0397 0.0768 0.1707
Echinococcus granulosus gamma secretase subunit aph 1 0.0276 0.0518 0.0517
Loa Loa (eye worm) transcriptional regulator 0.0125 0.0206 0.0206
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.013 0.0348
Plasmodium vivax metacaspase 1, putative 0.0173 0.0305 0.0961
Echinococcus multilocularis calpain 5 0.142 0.2885 0.2885
Onchocerca volvulus 0.1542 0.3137 0.6461
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0224 0.0411 0.0909
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0152 0.0151
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Brugia malayi prolyl oligopeptidase family protein 0.0354 0.0679 0.0678
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1542 0.3137 1
Echinococcus granulosus proteasome subunit alpha type 2 0.0041 0.0031 0.003
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0041 0.0031 0.0087
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0013 0.003
Echinococcus granulosus protein jagged 2 0.0044 0.0037 0.0036
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0041 0.0031 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0047 0.0047
Echinococcus granulosus histone deacetylase 6 0.01 0.0152 0.0151
Leishmania major centrin, putative 0.0224 0.0411 0.0909
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0013 0.0012
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0039 0.0038
Leishmania major hypothetical protein, conserved 0.007 0.0092 0.0197
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0041 0.0031 0.0031
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0397 0.0768 0.2439
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.004
Toxoplasma gondii peptidase c13 family protein 0.0034 0.0017 0.003
Toxoplasma gondii proteasome subunit beta type, putative 0.0253 0.047 0.1041
Loa Loa (eye worm) hypothetical protein 0.3792 0.7795 0.7795
Schistosoma mansoni hypothetical protein 0.007 0.0092 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0039 0.0038
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0023 0.0023
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0251 0.0682
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0103 0.016 0.0159
Trypanosoma cruzi calmodulin, putative 0.0224 0.0411 0.0407
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0043 0.0042
Plasmodium vivax histone deacetylase, putative 0.01 0.0152 0.0474
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0041 0.0031 0.003
Echinococcus granulosus protein jagged 1 0.0044 0.0037 0.0036
Loa Loa (eye worm) prolyl oligopeptidase 0.0605 0.1199 0.1199
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Loa Loa (eye worm) hypothetical protein 0.0101 0.0155 0.0155
Toxoplasma gondii histone deacetylase HDAC2 0.0089 0.013 0.0281
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0041 0.0031 0.0075
Echinococcus granulosus cathepsin b 0.4858 1 1
Loa Loa (eye worm) hypothetical protein 0.0397 0.0768 0.0768
Leishmania major proteasome beta 7 subunit, putative 0.0041 0.0031 0.0061
Entamoeba histolytica GPI-anchor transamidase, putative 0.0034 0.0017 0.0042
Mycobacterium tuberculosis Probable peptidase 0.0889 0.1787 0.4517
Entamoeba histolytica hypothetical protein 0.0397 0.0768 0.2439
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Plasmodium vivax GPI-anchor transamidase, putative 0.0034 0.0017 0.0042
Echinococcus multilocularis cathepsin L 0.0861 0.1729 0.1728
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0415 0.0806 0.2215
Trichomonas vaginalis calpain, putative 0.0415 0.0806 0.2215
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0397 0.0768 0.2112
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0605 0.1198 0.1198
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0043 0.0042
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0354 0.0679 0.0678
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0039
Trypanosoma cruzi centrin, putative 0.0232 0.0426 0.0422
Echinococcus granulosus histone deacetylase 7 0.01 0.0152 0.0151
Trypanosoma cruzi cysteine peptidase, putative 0.0861 0.1729 0.1726
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2191 0.4481 0.448
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Brugia malayi Muscle positioning protein 4 0.0044 0.0037 0.0036
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0861 0.1729 0.4766
Toxoplasma gondii kringle domain-containing protein 0.007 0.0092 0.0197
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.017 0.0418
Loa Loa (eye worm) hypothetical protein 0.0106 0.0167 0.0167
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.017 0.0418
Giardia lamblia Proteasome subunit beta type 3 0.0041 0.0031 0.0075
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0173 0.0305 0.0304
Brugia malayi Calcium binding EGF domain containing protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.0305 0.0832
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0397 0.0768 0.2112
Echinococcus granulosus proteasome subunit beta type 7 0.0041 0.0031 0.003
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0092 0.0137 0.0425
Leishmania major proteasome beta 3 subunit, putative 0.0041 0.0031 0.0061
Echinococcus multilocularis Glycosyl transferase, family 35 0.0123 0.02 0.0199
Leishmania major kinesin, putative 0.1005 0.2026 0.4517
Brugia malayi Angiotensin-converting enzyme family protein 0.0605 0.1198 0.1197
Echinococcus multilocularis microtubule associated protein 2 0.1591 0.3239 0.3238
Trypanosoma cruzi cysteine protease, putative 0.0861 0.1729 0.1726
Loa Loa (eye worm) hypothetical protein 0.4858 1 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0045 0.0039 0.0097
Leishmania major hypothetical protein, conserved 0.0224 0.0411 0.0909
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0092 0.0137 0.0136
Onchocerca volvulus 0.0058 0.0066 0.0133
Echinococcus granulosus histone deacetylase 6 0.01 0.0152 0.0151
Brugia malayi Ets-domain containing protein 0.0071 0.0093 0.0092
Echinococcus granulosus caspase 2 0.0394 0.0762 0.0761
Toxoplasma gondii EGF family domain-containing protein 0.0044 0.0037 0.0074
Echinococcus multilocularis fat cadherin tumor suppressor 0.0044 0.0037 0.0036
Onchocerca volvulus 0.0201 0.0363 0.0745
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0397 0.0768 0.2439
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0251 0.0682
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.013 0.0126
Echinococcus granulosus fibropellin Ia 0.0044 0.0037 0.0036
Giardia lamblia 20S proteasome alpha subunit 6 0.0041 0.0031 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0039 0.0097
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0041 0.0031 0.0087
Loa Loa (eye worm) hypothetical protein 0.0108 0.017 0.017
Entamoeba histolytica glycogen phosphorylase, putative 0.0053 0.0056 0.0167
Brugia malayi Proteasome subunit alpha type 1 0.0041 0.0031 0.003
Toxoplasma gondii calcium-dependent protein kinase 0.0228 0.0418 0.0926
Echinococcus multilocularis proteasome (prosome, macropain) 0.0253 0.047 0.0469
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0146 0.0248 0.0248
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.017 0.046
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0233 0.0634
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0039 0.0038
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0206 0.0205
Schistosoma mansoni hypothetical protein 0.0415 0.0806 0.0805
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.2883
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0415 0.0806 0.0805
Leishmania major cathepsin L-like protease 0.1652 0.3365 0.7507
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0001 0.0001
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0041 0.0031 0.003
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0041 0.0031 0.0075
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0034 0.0017 0.003
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0041 0.0031 0.0087
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0013 0.003
Toxoplasma gondii troponin c, isotype gamma, putative 0.0224 0.0411 0.0909
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Brugia malayi Animal haem peroxidase family protein 0.0499 0.0979 0.0978
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Brugia malayi Papain family cysteine protease containing protein 0.0397 0.0768 0.0767
Entamoeba histolytica calmodulin, putative 0.0224 0.0411 0.1298
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1542 0.3137 0.3137
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Chlamydia trachomatis glycogen phosphorylase 0.0123 0.02 0.5
Loa Loa (eye worm) histone deacetylase 7A 0.01 0.0152 0.0152
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0415 0.0806 0.1791
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.013 0.0126
Leishmania major centrin, putative,caltractin, putative 0.0224 0.0411 0.0909
Brugia malayi prolyl oligopeptidase family protein 0.0605 0.1199 0.1198
Trypanosoma brucei metacaspase 5, putative 0.0173 0.0305 0.0673
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0248 0.0247
Brugia malayi CXXC zinc finger family protein 0.0061 0.0073 0.0072
Onchocerca volvulus 0.0045 0.004 0.0081
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.0806 0.0802
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0233 0.0634
Entamoeba histolytica cysteine proteinase, putative 0.1542 0.3137 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0397 0.0768 0.2439
Plasmodium falciparum metacaspase-like protein 0.0173 0.0305 0.0961
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0397 0.0768 0.2439
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0051 0.0052 0.0051
Trypanosoma cruzi oligopeptidase b 0.0889 0.1787 0.1784
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0041 0.0031 0.0087
Brugia malayi PXA domain containing protein 0.0045 0.0039 0.0038
Mycobacterium ulcerans hypothetical protein 0.0291 0.0548 0.3043
Entamoeba histolytica cysteine protease, putative 0.0397 0.0768 0.2439
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0397 0.0768 0.2112
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.004 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Echinococcus multilocularis geminin 0.0342 0.0655 0.0654
Trypanosoma brucei proteasome beta 6 subunit 0.0145 0.0247 0.0543
Brugia malayi hypothetical protein 0.0221 0.0403 0.0402
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0041 0.0031 0.003
Giardia lamblia Cathepsin B precursor 0.0397 0.0768 0.2112
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0041 0.0031 0.0087
Loa Loa (eye worm) hypothetical protein 0.0108 0.017 0.017
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0397 0.0768 0.0767
Toxoplasma gondii hypothetical protein 0.0045 0.004 0.0082
Entamoeba histolytica calmodulin, putative 0.0224 0.0411 0.1298
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0039 0.0038
Brugia malayi proteasome subunit alpha type 2 0.0041 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0012
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.013 0.0348
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0201 0.0363 0.0363
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0224 0.0411 0.0407
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0248 0.0247
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0012 0.0012
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0039 0.0038
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.017 0.0925
Plasmodium vivax centrin-1, putative 0.0224 0.0411 0.1298
Echinococcus multilocularis glycogen phosphorylase 0.0123 0.02 0.0199
Brugia malayi proteasome subunit alpha type 6 0.0041 0.0031 0.003
Toxoplasma gondii EF hand domain-containing protein 0.0224 0.0411 0.0909
Schistosoma mansoni neprilysin-2 (M13 family) 0.0051 0.0052 0.0051
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0041 0.0031 0.0087
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0224 0.0411 0.1124
Echinococcus granulosus calcium uptake protein 1 0.0228 0.0418 0.0417
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0043 0.0042
Onchocerca volvulus 0.2372 0.4856 1
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0041 0.0031 0.003
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0464 0.0907 0.0907
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.6436
Onchocerca volvulus 0.0044 0.0037 0.0074
Plasmodium vivax SET domain protein, putative 0.0103 0.016 0.0498
Trypanosoma brucei histone deacetylase, putative 0.01 0.0152 0.0332
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0397 0.0768 0.2112
Schistosoma mansoni lamin 0.0026 0.0001 0.0000090515
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0101 0.0155 0.038
Loa Loa (eye worm) beta-lactamase 0.0108 0.017 0.017
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0039 0.0038
Brugia malayi prolyl oligopeptidase family protein 0.2191 0.4481 0.448
Trichomonas vaginalis calcium binding proteins, putative 0.0224 0.0411 0.1124
Brugia malayi GCC2 and GCC3 family protein 0.0044 0.0037 0.0036
Schistosoma mansoni cell polarity protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) ctsf protein 0.1542 0.3137 0.3137
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.017 0.0925
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0041 0.0031 0.0027
Toxoplasma gondii ABC1 family protein 0.0108 0.017 0.0372
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0045 0.004 0.0082
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.004
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0041 0.0031 0.0087
Trypanosoma brucei kinesin, putative 0.1005 0.2026 0.4517
Trichomonas vaginalis calmodulin, putative 0.0224 0.0411 0.1124
Entamoeba histolytica protein kinase, putative 0.1005 0.2026 0.6453
Plasmodium vivax unspecified product 0.0397 0.0768 0.2439
Leishmania major cathepsin L-like protease 0.1542 0.3137 0.7
Echinococcus granulosus slit 2 protein 0.0044 0.0037 0.0036
Giardia lamblia Cathepsin L precursor 0.0397 0.0768 0.2112
Schistosoma mansoni laminin gamma-3 chain 0.0044 0.0037 0.0036
Giardia lamblia Encystation-specific protease 0.0397 0.0768 0.2112
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0041 0.0031 0.0087
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4017 0.8259 0.8259
Mycobacterium tuberculosis Conserved hypothetical protein 0.0291 0.0548 0.1374
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0098 0.0149 0.0148
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0039 0.0039
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0041 0.0031 0.0027
Entamoeba histolytica cysteine protease, putative 0.0397 0.0768 0.2439
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0041 0.0031 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.016 0.0159
Giardia lamblia GPI-anchor transamidase, putative 0.0034 0.0017 0.0037
Giardia lamblia 20S proteasome alpha subunit 3 0.0041 0.0031 0.0075
Onchocerca volvulus Cathepsin F homolog 0.1542 0.3137 0.6461
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Onchocerca volvulus 0.0201 0.0363 0.0745
Entamoeba histolytica glycogen phosphorylase, putative 0.0053 0.0056 0.0167
Plasmodium falciparum histone deacetylase, putative 0.01 0.0152 0.0474
Brugia malayi Animal haem peroxidase family protein 0.0499 0.0979 0.0978
Leishmania major calpain protease-like protein 0.0415 0.0806 0.1791
Toxoplasma gondii hypothetical protein 0.0257 0.0478 0.1058
Echinococcus granulosus glycogen phosphorylase 0.0123 0.02 0.0199
Giardia lamblia 20S proteasome alpha subunit 1 0.0041 0.0031 0.0075
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.0802
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0013 0.0013
Trypanosoma brucei histone deacetylase 3 0.01 0.0152 0.0332
Loa Loa (eye worm) hypothetical protein 0.0075 0.0101 0.0101
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0041 0.0031 0.003
Giardia lamblia Cathepsin L precursor 0.0397 0.0768 0.2112
Brugia malayi calpain family protein 1 0.3792 0.7795 0.7794
Echinococcus granulosus transmembrane protease serine 3 0.0201 0.0363 0.0362
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0147 0.0251 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0039 0.0097
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0041 0.0031 0.0061
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0711 0.1418 0.1418
Entamoeba histolytica cysteine proteinase, putative 0.1542 0.3137 1
Loa Loa (eye worm) animal heme peroxidase 0.0499 0.0979 0.0979
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0415 0.0806 0.0805
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0041 0.0031 0.0087
Plasmodium vivax proteasome subunit beta type-4, putative 0.0041 0.0031 0.0087
Echinococcus granulosus chromatin regulatory protein sir2 0.0125 0.0206 0.0205
Trypanosoma cruzi cysteine peptidase, putative 0.0464 0.0907 0.0904
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0041 0.0031 0.0027
Plasmodium vivax serine-repeat antigen (SERA) 0.0397 0.0768 0.2439
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0092 0.0137 0.0297
Schistosoma mansoni notch 0.0044 0.0037 0.0036
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0333 0.0332
Brugia malayi Cathepsin L-like precursor 0.1542 0.3137 0.3137
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0397 0.0768 0.2112
Echinococcus multilocularis cpg binding protein 0.0065 0.008 0.0079
Leishmania major proteasome alpha 1 subunit, putative 0.0041 0.0031 0.0061
Leishmania major phospholipase c-like protein 0.0224 0.0411 0.0909
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1542 0.3137 1
Entamoeba histolytica hypothetical protein 0.0045 0.0039 0.0112
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0397 0.0768 0.2112
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.0137 0.0368
Schistosoma mansoni cathepsin F (C01 family) 0.1542 0.3137 0.3137
Mycobacterium ulcerans beta-lactamase 0.0108 0.017 0.0925
Brugia malayi Ets-domain containing protein 0.0071 0.0093 0.0092
Trichomonas vaginalis peptide N-glycanase, putative 0.0291 0.0548 0.1503
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0006 0.0005
Giardia lamblia Sirtuin type 2 0.0032 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.007 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0039 0.0038
Schistosoma mansoni hypothetical protein 0.0113 0.018 0.0179
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0241 0.1322
Brugia malayi calpain 5 0.0415 0.0806 0.0805
Schistosoma mansoni cathepsin B (C01 family) 0.0397 0.0768 0.0767
Brugia malayi EGF-like domain containing protein 0.0044 0.0037 0.0036
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Loa Loa (eye worm) hypothetical protein 0.0224 0.0411 0.0411
Entamoeba histolytica cysteine protease, putative 0.0861 0.1729 0.5504
Loa Loa (eye worm) CYP4Cod1 0.0037 0.0023 0.0023
Brugia malayi transcriptional regulator, Sir2 family protein 0.0125 0.0206 0.0205
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0013 0.0026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Entamoeba histolytica cysteine protease, putative 0.0397 0.0768 0.2439
Giardia lamblia Cysteine protease 0.0397 0.0768 0.2112
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.0806 0.0802
Schistosoma mansoni hypothetical protein 0.0224 0.0411 0.041
Trypanosoma cruzi cysteine proteinase, putative 0.0861 0.1729 0.1726
Schistosoma mansoni notch 0.0044 0.0037 0.0036
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0257 0.0478 0.1512
Onchocerca volvulus 0.0178 0.0315 0.0647
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0031 0.0075
Plasmodium falciparum serine repeat antigen 4 0.0397 0.0768 0.2439
Onchocerca volvulus 0.0108 0.017 0.0349
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0253 0.047 0.0469
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0397 0.0768 0.2112
Schistosoma mansoni Mername-AA248 (C02 family) 0.142 0.2885 0.2885
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0173 0.0305 0.0673
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0097 0.0148 0.0148
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0041 0.0031 0.0061
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0499 0.0979 0.0979
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0041 0.0031 0.003
Onchocerca volvulus 0.0045 0.004 0.0081
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0041 0.0031 0.0031
Brugia malayi Histone deacetylase 1 0.0089 0.013 0.0129
Brugia malayi carbohydrate phosphorylase 0.0123 0.02 0.0199
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0041 0.0031 0.0027
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0201 0.0363 0.0362
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Brugia malayi cathepsin L-like cysteine proteinase 0.0397 0.0768 0.0767
Trypanosoma brucei histone deacetylase 1 0.0089 0.013 0.0281
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0039 0.0038
Toxoplasma gondii histone deacetylase HDAC3 0.0089 0.013 0.0281
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0173 0.0305 0.0832
Schistosoma mansoni hypothetical protein 0.0291 0.0548 0.0547
Echinococcus multilocularis glycogen phosphorylase 0.0123 0.02 0.0199
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0013 0.0021
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0013 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0248 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Schistosoma mansoni microtubule-associated protein tau 0.1591 0.3239 0.3238
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0889 0.1787 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.0806 0.1791
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0056 0.0055
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0041 0.0031 0.0027
Brugia malayi Cathepsin L-like precursor 0.1078 0.2177 0.2176
Leishmania major proteasome beta 5 subunit, putative 0.0253 0.047 0.1041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0056 0.0055
Echinococcus multilocularis notch 0.0044 0.0037 0.0036
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0039 0.0039
Echinococcus multilocularis gamma secretase subunit aph 1 0.0276 0.0518 0.0517
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0132 0.0219 0.0686
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0415 0.0806 0.1791
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.0223 0.0222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1652 0.3365 0.7507
Entamoeba histolytica cysteine proteinase, putative 0.0861 0.1729 0.5504
Leishmania major programmed cell death 6 protein-like protein 0.0224 0.0411 0.0909
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0044 0.0037 0.0074
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0006 0.0004
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0152 0.0149
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0397 0.0768 0.2439
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0861 0.1729 0.4766
Echinococcus multilocularis centrin 2 0.0224 0.0411 0.041
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.017 0.0169
Onchocerca volvulus 0.0044 0.0037 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1542 0.3137 0.8658
Schistosoma mansoni peroxidasin 0.0499 0.0979 0.0978
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0397 0.0768 0.2439
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0041 0.0031 0.0087
Schistosoma mansoni cellular tumor antigen P53 0.0107 0.0167 0.0166
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0041 0.0031 0.003
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.142 0.2885 0.6436
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0031 0.0075
Giardia lamblia Cathepsin B precursor 0.1777 0.3623 1
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0041 0.0031 0.003
Brugia malayi PAN domain containing protein 0.0045 0.004 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0201 0.0363 0.0362
Echinococcus granulosus survival motor neuron protein 1 0.0282 0.053 0.053
Entamoeba histolytica cysteine proteinase, putative 0.0861 0.1729 0.5504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Onchocerca volvulus Dual oxidase homolog 0.0499 0.0979 0.2014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1542 0.3137 0.8658
Schistosoma mansoni hypothetical protein 0.0221 0.0403 0.0403
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0045 0.0039 0.0038
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0224 0.0411 0.041
Echinococcus multilocularis Regulator of G protein signaling 20 0.0045 0.0039 0.0038
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0041 0.0031 0.0061
Schistosoma mansoni ef hand domain family member A2 0.0224 0.0411 0.041
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0041 0.0031 0.0031
Toxoplasma gondii microneme protein MIC4 0.0045 0.004 0.0082
Loa Loa (eye worm) trypsin family protein 0.0201 0.0363 0.0363
Toxoplasma gondii calmodulin CAM1 0.0228 0.0418 0.0926
Onchocerca volvulus 0.0029 0.0006 0.001

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.9012 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (binding) = 2.8184 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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