Detailed information for compound 1516958

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 244.61 | Formula: C8H6ClFN4O2
  • H donors: 0 H acceptors: 4 LogP: 1.47 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)Cn1cnc2c1nc(F)nc2Cl
  • InChi: 1S/C8H6ClFN4O2/c1-16-4(15)2-14-3-11-5-6(9)12-8(10)13-7(5)14/h3H,2H2,1H3
  • InChiKey: GMBUXGKOXHYRFX-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0035 0.0035
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0139 0.0369 0.0361
Mycobacterium ulcerans hypothetical protein 0.0288 0.0847 0.3807
Onchocerca volvulus 0.0042 0.0058 0.0101
Trypanosoma cruzi cysteine peptidase, putative 0.1213 0.3822 0.3817
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0042 0.0058 0.0054
Leishmania major cysteine peptidase A (CPA) 0.1108 0.3485 0.6496
Echinococcus granulosus neuronal calcium sensor 0.0139 0.0369 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0614 0.1895 0.3525
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2453 0.7809 0.7809
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0277 0.0811 0.2203
Trypanosoma cruzi cysteine protease, putative 0.0614 0.1895 0.1888
Trichomonas vaginalis calcium binding protein, putative 0.0139 0.0369 0.0988
Entamoeba histolytica calcium binding family protein 0.0139 0.0369 0.1036
Echinococcus granulosus survival motor neuron protein 1 0.026 0.0759 0.0755
Loa Loa (eye worm) hypothetical protein 0.006 0.0115 0.0111
Echinococcus multilocularis prolyl endopeptidase 0.1691 0.536 0.5358
Brugia malayi hypothetical protein 0.0168 0.0463 0.0459
Schistosoma mansoni calmodulin 0.0139 0.0369 0.0369
Trypanosoma cruzi I/6 autoantigen, putative 0.0139 0.0369 0.0361
Echinococcus multilocularis histone deacetylase 7 0.0101 0.0246 0.0242
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Plasmodium vivax serine-repeat antigen (SERA) 0.0277 0.0811 0.231
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0277 0.0811 0.0811
Loa Loa (eye worm) hypothetical protein 0.0255 0.0743 0.0739
Loa Loa (eye worm) glycogen phosphorylase 0.0121 0.0312 0.0308
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.005 0.0046
Echinococcus granulosus cathepsin L cysteine protease 0.0614 0.1895 0.1892
Trypanosoma cruzi cruzipain precursor, putative 0.0337 0.1006 0.0998
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0352 0.1055 0.1955
Loa Loa (eye worm) hypothetical protein 0.0043 0.0059 0.0055
Echinococcus granulosus cathepsin l1 0.1108 0.3485 0.3482
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0277 0.0811 0.2203
Schistosoma mansoni notch 0.0026 0.0004 0.0004
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0141 0.0376 0.0368
Plasmodium vivax centrin-1, putative 0.0139 0.0369 0.1036
Echinococcus granulosus glycogen phosphorylase 0.0121 0.0312 0.0308
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0277 0.0811 0.231
Loa Loa (eye worm) hypothetical protein 0.0139 0.0369 0.0365
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Trypanosoma brucei calmodulin, putative 0.0139 0.0369 0.0673
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0059 0.0059
Giardia lamblia Cathepsin L precursor 0.0277 0.0811 0.2212
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0215 0.0614 0.1743
Echinococcus granulosus calpain A 0.0868 0.2713 0.271
Onchocerca volvulus 0.003 0.0018 0.0026
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0036 0.0051
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0094 0.0223 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Brugia malayi A-kinase anchor protein 10, precursor 0.0043 0.0059 0.0055
Plasmodium vivax histone deacetylase 1, putative 0.009 0.021 0.0582
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.2556 0.2553
Leishmania major cathepsin L-like protease 0.1108 0.3485 0.6496
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0059 0.014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Onchocerca volvulus 0.0042 0.0058 0.0101
Mycobacterium tuberculosis Conserved hypothetical protein 0.0288 0.0847 0.1752
Echinococcus granulosus inhibitor of apoptosis protein 0.0187 0.0522 0.0518
Toxoplasma gondii microneme protein, putative 0.003 0.0018 0.0026
Onchocerca volvulus Glycogen phosphorylase homolog 0.0121 0.0312 0.0575
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0014
Leishmania major hypothetical protein, conserved 0.0139 0.0369 0.0673
Onchocerca volvulus 0.0757 0.2357 0.4393
Onchocerca volvulus 0.1108 0.3485 0.6498
Onchocerca volvulus 0.003 0.0018 0.0026
Brugia malayi Papain family cysteine protease containing protein 0.1108 0.3485 0.3482
Onchocerca volvulus 0.0035 0.0035 0.0058
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Trypanosoma brucei Calpain-like protein 1.2 0.0255 0.0743 0.1372
Onchocerca volvulus 0.0139 0.0369 0.068
Brugia malayi hypothetical protein 0.0236 0.0681 0.0678
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0026
Trichomonas vaginalis calcineurin B subunit, putative 0.0141 0.0376 0.101
Loa Loa (eye worm) hypothetical protein 0.0187 0.0522 0.0518
Trypanosoma brucei C-8 sterol isomerase, putative 0.0356 0.1066 0.1976
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Trypanosoma cruzi cruzipain precursor, putative 0.1213 0.3822 0.3817
Echinococcus granulosus EF HAND 1 calcium binding site 0.0139 0.0369 0.0365
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0255 0.0743 0.2015
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.021 0.0555
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.0052
Echinococcus granulosus histone deacetylase 3 0.009 0.021 0.0206
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0031
Mycobacterium tuberculosis Probable peptidase 0.0698 0.2167 0.4601
Onchocerca volvulus Cathepsin F homolog 0.1108 0.3485 0.6498
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0231 0.0227
Plasmodium falciparum serine repeat antigen 1 0.0277 0.0811 0.231
Leishmania major i/6 autoantigen-like protein 0.0139 0.0369 0.0673
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0014
Brugia malayi cathepsin Z-like cysteine proteinase 0.0277 0.0811 0.0807
Loa Loa (eye worm) cathepsin B 0.116 0.3653 0.3651
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0043 0.0059 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0381 0.0377
Onchocerca volvulus Cell death protein 3 homolog 0.0156 0.0424 0.0784
Onchocerca volvulus 0.0139 0.0369 0.068
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0698 0.2167 0.4033
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0156 0.0423 0.042
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0062 0.0158
Mycobacterium tuberculosis Long conserved protein 0.0288 0.0847 0.1752
Loa Loa (eye worm) hypothetical protein 0.0043 0.0059 0.0055
Giardia lamblia Cathepsin L precursor 0.0277 0.0811 0.2212
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0042 0.0058 0.0101
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0056 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0059 0.0059
Trichomonas vaginalis calmodulin, putative 0.0139 0.0369 0.0988
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2453 0.7809 0.7808
Brugia malayi Cell death protein 3 precursor 0.0156 0.0424 0.042
Brugia malayi Trypsin family protein 0.0156 0.0423 0.042
Echinococcus multilocularis histone deacetylase 6 0.0101 0.0246 0.0242
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.005 0.0121
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0139 0.0369 0.0365
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0344 0.0668
Loa Loa (eye worm) hypothetical protein 0.0069 0.0144 0.014
Trichomonas vaginalis set domain proteins, putative 0.0757 0.2356 0.6442
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Schistosoma mansoni histone deacetylase 1 2 3 0.0043 0.0061 0.0061
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0614 0.1895 0.1895
Loa Loa (eye worm) histone deacetylase 1 0.009 0.021 0.0206
Trichomonas vaginalis hypothetical protein 0.0255 0.0743 0.2015
Leishmania major histone deacetylase, putative 0.009 0.021 0.0378
Schistosoma mansoni hypothetical protein 0.0187 0.0522 0.0522
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0277 0.0811 0.2203
Mycobacterium tuberculosis Conserved hypothetical protein 0.0288 0.0847 0.1752
Brugia malayi Papain family cysteine protease containing protein 0.0277 0.0811 0.0807
Entamoeba histolytica glycogenphosphorylase, putative 0.0052 0.0091 0.0237
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0277 0.0811 0.231
Echinococcus multilocularis EF hand domain containing family member A2 0.0141 0.0376 0.0372
Onchocerca volvulus 0.0236 0.0681 0.1265
Toxoplasma gondii cathepsin CPL 0.1108 0.3485 0.6498
Plasmodium vivax calpain, putative 0.0868 0.2713 0.7779
Echinococcus granulosus flap endonuclease 1 0.0027 0.0008 0.0004
Mycobacterium ulcerans zinc metalloprotease 0.0094 0.0223 0.0881
Trypanosoma brucei centrin, putative 0.0139 0.0369 0.0673
Plasmodium falciparum serine repeat antigen 6 0.0277 0.0811 0.231
Brugia malayi histone deacetylase 1 (HD1) 0.009 0.021 0.0206
Trichomonas vaginalis glycogen phosphorylase, putative 0.0121 0.0312 0.0833
Leishmania major programmed cell death 6 protein-like protein 0.0139 0.0369 0.0673
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0031
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Entamoeba histolytica glycogen phosphorylase, putative 0.0121 0.0312 0.0874
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.116 0.3653 0.3648
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0868 0.2713 0.2707
Brugia malayi histone deacetylase 11 0.0043 0.0061 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0614 0.0606
Onchocerca volvulus 0.1108 0.3485 0.6498
Entamoeba histolytica glycogen phosphorylase, putative 0.0121 0.0312 0.0874
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.0052
Schistosoma mansoni Mername-AA248 (C02 family) 0.0868 0.2713 0.2713
Brugia malayi hypothetical protein 0.0042 0.0058 0.0054
Brugia malayi hypothetical protein 0.026 0.0759 0.0755
Loa Loa (eye worm) hypothetical protein 0.0069 0.0144 0.014
Trypanosoma brucei calpain-like protein, putative 0.0868 0.2713 0.5053
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0139 0.0369 0.0365
Schistosoma mansoni hypothetical protein 0.0183 0.0511 0.0511
Echinococcus multilocularis neurocalcin 0.0139 0.0369 0.0365
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.009 0.0212 0.0212
Onchocerca volvulus Neurogenic locus notch homolog 0.0026 0.0005 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0025 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0059 0.014
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0094 0.0223 0.0405
Echinococcus multilocularis histone deacetylase 8 0.0043 0.0061 0.0057
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0277 0.0811 0.2203
Leishmania major calmodulin, putative 0.0139 0.0369 0.0673
Giardia lamblia Cathepsin B precursor 0.0277 0.0811 0.2212
Trichomonas vaginalis calmodulin, putative 0.0139 0.0369 0.0988
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0356 0.1066 0.1062
Schistosoma mansoni cathepsin D (A01 family) 0.0232 0.0667 0.0667
Echinococcus multilocularis dnaJ subfamily B 0.0455 0.1385 0.1382
Schistosoma mansoni mitochondrial solute carrier 0.0139 0.0369 0.0369
Echinococcus granulosus Glycosyl transferase family 35 0.0121 0.0312 0.0308
Onchocerca volvulus 0.0032 0.0025 0.0039
Trypanosoma brucei caltractin, putative 0.0142 0.038 0.0695
Onchocerca volvulus 0.0156 0.0423 0.0783
Entamoeba histolytica cysteine protease, putative 0.1108 0.3485 1
Onchocerca volvulus Cathepsin L homolog 0.0277 0.0811 0.1507
Trypanosoma cruzi caltractin, putative 0.0139 0.0369 0.0361
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0187 0.0522 0.0518
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0139 0.0369 0.1036
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0059 0.0055
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0035 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0811 0.2203
Toxoplasma gondii ABC1 family protein 0.0035 0.0035 0.0058
Onchocerca volvulus 0.003 0.0018 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0035 0.0077
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0026
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0352 0.1055 0.1962
Trypanosoma cruzi centrin, putative 0.0142 0.038 0.0372
Plasmodium vivax plasmepsin V, putative 0.0042 0.0058 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Plasmodium vivax vivapain-2 0.1108 0.3485 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0043 0.0059 0.0055
Trypanosoma cruzi calmodulin, putative 0.0139 0.0369 0.0361
Toxoplasma gondii prolyl endopeptidase 0.1691 0.536 1
Schistosoma mansoni calpain (C02 family) 0.0868 0.2713 0.2713
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0139 0.0369 0.0361
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0059 0.0055
Echinococcus granulosus calbindin 32 0.0141 0.0376 0.0372
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0215 0.0614 0.1139
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Trichomonas vaginalis calpain, putative 0.0255 0.0743 0.2015
Toxoplasma gondii preprocathepsin c precursor, putative 0.0277 0.0811 0.1507
Onchocerca volvulus Deterin homolog 0.0187 0.0522 0.0967
Brugia malayi Pre-SET motif family protein 0.0096 0.0231 0.0227
Trypanosoma brucei hypothetical protein, conserved 0.0139 0.0369 0.0673
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1108 0.3485 0.3482
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.0217 0.0213
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.0423
Trypanosoma cruzi oligopeptidase b 0.0698 0.2167 0.216
Loa Loa (eye worm) hypothetical protein 0.0071 0.0149 0.0145
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0004
Onchocerca volvulus 0.0055 0.0099 0.0178
Loa Loa (eye worm) hypothetical protein 0.0156 0.0423 0.042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.2707
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Leishmania major cathepsin L-like protease 0.1108 0.3485 0.6496
Entamoeba histolytica cysteine protease, putative 0.0277 0.0811 0.231
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0074 0.0074
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0352 0.1055 0.1955
Trypanosoma brucei histone deacetylase, putative 0.0101 0.0246 0.0444
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0277 0.0811 0.0811
Plasmodium falciparum plasmepsin V 0.0042 0.0058 0.0143
Schistosoma mansoni cathepsin B (C01 family) 0.0277 0.0811 0.0811
Brugia malayi cathepsin L precursor 0.0277 0.0811 0.0807
Echinococcus granulosus EF hand domain containing family member A2 0.0141 0.0376 0.0372
Loa Loa (eye worm) histone deacetylase 0.0101 0.0246 0.0242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0614 0.1895 0.3525
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.021 0.0555
Entamoeba histolytica cysteine proteinase 1, putative 0.0614 0.1895 0.5427
Loa Loa (eye worm) aspartyl protease 6 0.0042 0.0058 0.0054
Echinococcus granulosus histone deacetylase 8 0.0043 0.0061 0.0057
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0776 0.2417 0.2414
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0277 0.0811 0.2212
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0056 0.0052
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.2707
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0026
Echinococcus multilocularis Transglutaminase 0.0288 0.0847 0.0843
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0277 0.0811 0.2203
Echinococcus multilocularis cpg binding protein 0.0034 0.0031 0.0027
Entamoeba histolytica hypothetical protein, conserved 0.0215 0.0614 0.1743
Giardia lamblia Encystation-specific protease 0.0277 0.0811 0.2212
Trichomonas vaginalis calmodulin, putative 0.0139 0.0369 0.0988
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1108 0.3485 0.3482
Brugia malayi Peroxidasin 0.0236 0.0681 0.0678
Brugia malayi Ets-domain containing protein 0.007 0.0148 0.0144
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0277 0.0811 0.231
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0255 0.0743 0.0735
Brugia malayi Animal haem peroxidase family protein 0.0236 0.0681 0.0678
Schistosoma mansoni calpain-7 (C02 family) 0.0871 0.2722 0.2722
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Echinococcus granulosus calpain 0.0868 0.2713 0.271
Echinococcus granulosus neurocalcin 0.0139 0.0369 0.0365
Loa Loa (eye worm) fli-1 protein 0.0213 0.0608 0.0604
Toxoplasma gondii microneme protein MIC17C 0.003 0.0018 0.0026
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0343 0.034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Schistosoma mansoni ap endonuclease 0.004 0.005 0.005
Echinococcus multilocularis cathepsin L 0.0614 0.1895 0.1892
Plasmodium vivax unspecified product 0.0337 0.1006 0.287
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0062 0.0154
Giardia lamblia Hypothetical protein 0.0277 0.0811 0.2212
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0054
Schistosoma mansoni peroxidasin 0.0236 0.0681 0.0681
Toxoplasma gondii proteasome subunit beta type, putative 0.009 0.0212 0.0389
Brugia malayi Calmodulin-like protein 0.0139 0.0369 0.0365
Echinococcus granulosus cysteine protease 0.0614 0.1895 0.1892
Echinococcus multilocularis centrin 2 0.0139 0.0369 0.0365
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.007 0.0148 0.0144
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0026 0.0004 0.0004
Onchocerca volvulus 0.1446 0.4572 0.8529
Loa Loa (eye worm) hypothetical protein 0.0055 0.0099 0.0095
Trypanosoma cruzi cysteine proteinase, putative 0.0614 0.1895 0.1888
Toxoplasma gondii calmodulin CAM1 0.0141 0.0376 0.0695
Leishmania major calcineurin B subunit, putative 0.0139 0.0369 0.0673
Brugia malayi beta-lactamase family protein 0.0035 0.0035 0.0031
Plasmodium falciparum plasmepsin X 0.0205 0.058 0.1644
Schistosoma mansoni histone deacetylase 0.009 0.021 0.021
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0093 0.0089
Brugia malayi prolyl oligopeptidase family protein 0.0215 0.0614 0.061
Onchocerca volvulus 0.0156 0.0423 0.0783
Trichomonas vaginalis histone deacetylase, putative 0.009 0.021 0.0555
Plasmodium falciparum serine repeat antigen 9 0.0277 0.0811 0.231
Plasmodium vivax vivapain-2 0.1108 0.3485 1
Toxoplasma gondii hypothetical protein 0.003 0.0018 0.0026
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.0246 0.0238
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0868 0.2713 0.2707
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0062 0.01
Loa Loa (eye worm) animal heme peroxidase 0.0236 0.0681 0.0678
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0277 0.0811 0.0807
Echinococcus multilocularis calpain family protein 1, d 0.1702 0.5393 0.5391
Trichomonas vaginalis histone deacetylase, putative 0.009 0.021 0.0555
Entamoeba histolytica protein kinase, putative 0.0613 0.1892 0.5419
Loa Loa (eye worm) ctsf protein 0.1108 0.3485 0.3482
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0052 0.0091 0.012
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0056 0.0097
Brugia malayi Blistered cuticle protein 3 0.0236 0.0681 0.0678
Brugia malayi Proteasome A-type and B-type family protein 0.009 0.0212 0.0208
Toxoplasma gondii EF hand domain-containing protein 0.0139 0.0369 0.068
Entamoeba histolytica grainin, putative 0.0141 0.0376 0.1059
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0277 0.0811 0.231
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0139 0.0369 0.0361
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0277 0.0811 0.0807
Onchocerca volvulus 0.0139 0.0369 0.0681
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0369 0.0369
Echinococcus multilocularis apoptotic protease activating factor 1 0.0139 0.0369 0.0365
Echinococcus granulosus histone deacetylase 6 0.0101 0.0246 0.0242
Trypanosoma brucei calpain, putative 0.0255 0.0743 0.1372
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Plasmodium falciparum calpain 0.0255 0.0743 0.2112
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0059 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0811 0.2203
Brugia malayi cathepsin L-like precursor 0.0771 0.2401 0.2398
Trypanosoma cruzi kinesin, putative 0.0613 0.1892 0.1885
Loa Loa (eye worm) hypothetical protein 0.0215 0.0614 0.061
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0242 0.0234
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Brugia malayi prolyl oligopeptidase family protein 0.0215 0.0614 0.061
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0644 0.1314
Trypanosoma brucei I/6 autoantigen 0.0139 0.0369 0.0673
Schistosoma mansoni reticulocalbin 0.0139 0.0369 0.0369
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0139 0.0369 0.1036
Entamoeba histolytica cysteine proteinase, putative 0.0614 0.1895 0.5427
Schistosoma mansoni cathepsin s 0.0337 0.1006 0.1006
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0337 0.1006 0.1002
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.005 0.5
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0059 0.0055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.0423
Brugia malayi Cytochrome P450 family protein 0.0035 0.0036 0.0031
Entamoeba histolytica cysteine protease, putative 0.0277 0.0811 0.231
Entamoeba histolytica calcium-binding protein, putative 0.0139 0.0369 0.1036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0337 0.1006 0.1002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0344 0.0628
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.0811 0.2203
Brugia malayi gamma-secretase subunit aph-1 0.0255 0.0743 0.0739
Leishmania major cathepsin L-like protease 0.1213 0.3822 0.7125
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0046 0.0071 0.0179
Brugia malayi calpain family protein 1 0.2314 0.7363 0.7362
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.0058 0.0143
Schistosoma mansoni hypothetical protein 0.0046 0.0071 0.0071
Schistosoma mansoni reticulocalbin 0.0141 0.0376 0.0376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Plasmodium vivax histone deacetylase, putative 0.0101 0.0246 0.0684
Trypanosoma cruzi calmodulin, putative 0.0139 0.0369 0.0361
Plasmodium falciparum cysteine proteinase falcipain 3 0.1108 0.3485 1
Mycobacterium tuberculosis Hypothetical protein 0.0288 0.0847 0.1752
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.5053
Plasmodium falciparum plasmepsin IV 0.0042 0.0058 0.0143
Schistosoma mansoni cpg binding protein 0.0034 0.0031 0.0031
Mycobacterium tuberculosis Conserved protein 0.0288 0.0847 0.1752
Schistosoma mansoni inhibitor of apoptosis protein 0.0187 0.0522 0.0522
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1691 0.536 0.536
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0052 0.0091 0.0261
Entamoeba histolytica cysteine proteinase 2 0.0614 0.1895 0.5427
Trichomonas vaginalis calpain, putative 0.0255 0.0743 0.2015
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0062 0.0062
Onchocerca volvulus 0.0771 0.2401 0.4475
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0156 0.0423 0.042
Trypanosoma brucei centrin-3 0.0142 0.038 0.0695
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0139 0.0369 0.0369
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0014
Echinococcus granulosus cathepsin L 0.0614 0.1895 0.1892
Brugia malayi Cathepsin L-like precursor 0.0771 0.2401 0.2398
Trichomonas vaginalis calmodulin, putative 0.0139 0.0369 0.0988
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.0423
Giardia lamblia Cathepsin L precursor 0.0277 0.0811 0.2212
Onchocerca volvulus 0.0236 0.0681 0.1265
Mycobacterium ulcerans proteasome PrcB 0.009 0.0212 0.0832
Loa Loa (eye worm) hypothetical protein 0.0277 0.0811 0.0807
Schistosoma mansoni calpain-2 (C02 family) 0.0255 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0277 0.0811 0.0807
Loa Loa (eye worm) hypothetical protein 0.0071 0.0149 0.0145
Trichomonas vaginalis esterase, putative 0.0035 0.0035 0.0073
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.0423
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Trichomonas vaginalis calcium binding protein, putative 0.0139 0.0369 0.0988
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0344 0.1452
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0062 0.0058
Loa Loa (eye worm) histone deacetylase 7A 0.0101 0.0246 0.0242
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0277 0.0811 0.0811
Loa Loa (eye worm) animal heme peroxidase 0.0236 0.0681 0.0678
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0277 0.0811 0.231
Echinococcus multilocularis cysteine protease 0.1108 0.3485 0.3482
Onchocerca volvulus Cathepsin L homolog 0.1108 0.3485 0.6498
Loa Loa (eye worm) hypothetical protein 0.0094 0.0223 0.0219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.000000018742
Loa Loa (eye worm) hypothetical protein 0.0156 0.0423 0.042
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2453 0.7809 0.7809
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0008 0.0004
Echinococcus multilocularis calpain 7 (C02 family) 0.0868 0.2713 0.271
Loa Loa (eye worm) RGS-3 protein 0.0043 0.0059 0.0055
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus multilocularis microtubule associated protein 2 0.1502 0.4752 0.475
Giardia lamblia Cathepsin L precursor 0.0277 0.0811 0.2212
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1108 0.3485 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0109 0.0105
Plasmodium vivax histone deacetylase, putative 0.0043 0.0061 0.0152
Echinococcus multilocularis programmed cell death protein 0.0142 0.038 0.0376
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0004 0.000000018742
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Brugia malayi Trypsin family protein 0.0156 0.0423 0.042
Brugia malayi Pepsin A precursor 0.0042 0.0058 0.0054
Leishmania major centrin, putative 0.0139 0.0369 0.0673
Brugia malayi histone deacetylase 3 (HD3) 0.009 0.021 0.0206
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0004 0.0004
Loa Loa (eye worm) beta-lactamase 0.0035 0.0035 0.0031
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0522 0.0518
Schistosoma mansoni cathepsin S (C01 family) 0.0277 0.0811 0.0811
Brugia malayi Flap endonuclease-1 0.0027 0.0008 0.0004
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Schistosoma mansoni cathepsin F (C01 family) 0.1108 0.3485 0.3485
Schistosoma mansoni rab 0.0139 0.0369 0.0369
Toxoplasma gondii proteasome subunit beta type 1, putative 0.007 0.0148 0.0268
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0036 0.0031
Echinococcus granulosus gamma secretase subunit aph 1 0.0255 0.0743 0.0739
Giardia lamblia Cysteine protease 0.0277 0.0811 0.2212
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0876 0.2738 0.2732
Echinococcus multilocularis histone deacetylase 6 0.0101 0.0246 0.0242
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0231 0.0231
Echinococcus multilocularis hypothetical protein 0.0868 0.2713 0.271
Plasmodium vivax aspartyl protease, putative 0.0205 0.058 0.1644
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.0059 0.0059
Plasmodium falciparum serine repeat antigen 5 0.0277 0.0811 0.231
Loa Loa (eye worm) hypothetical protein 0.0071 0.0149 0.0145
Trypanosoma cruzi cysteine peptidase, putative 0.1108 0.3485 0.3479
Giardia lamblia Hypothetical protein 0.0141 0.0376 0.102
Brugia malayi Animal haem peroxidase family protein 0.0236 0.0681 0.0678
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0047 0.0074 0.0074
Trypanosoma brucei calpain, putative 0.0255 0.0743 0.1372
Loa Loa (eye worm) hypothetical protein 0.0277 0.0811 0.0807
Trichomonas vaginalis conserved hypothetical protein 0.0215 0.0614 0.1662
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0008 0.0011
Trypanosoma cruzi histone deacetylase 1, putative 0.009 0.021 0.0202
Brugia malayi proteasome subunit beta type 1 0.007 0.0148 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0043 0.0059 0.0055
Entamoeba histolytica cysteine protease, putative 0.0277 0.0811 0.231
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.021 0.0555
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0043 0.0059 0.0055
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0062 0.0054
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0059 0.0059
Trypanosoma brucei calpain-like protein, putative 0.0868 0.2713 0.5053
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0277 0.0811 0.2212
Toxoplasma gondii EFHC1, putative 0.0139 0.0369 0.068
Brugia malayi calpain D 0.0255 0.0743 0.0739
Brugia malayi PXA domain containing protein 0.0043 0.0059 0.0055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.0423
Loa Loa (eye worm) hypothetical protein 0.0043 0.0059 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0231 0.0231
Entamoeba histolytica cysteine proteinase, putative 0.1108 0.3485 1
Toxoplasma gondii histone deacetylase HDAC4 0.0043 0.0061 0.0107
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0056 0.0052
Trypanosoma brucei antigen, putative 0.0868 0.2713 0.5053
Schistosoma mansoni hypothetical protein 0.0139 0.0369 0.0369
Onchocerca volvulus 0.1108 0.3485 0.6498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Onchocerca volvulus 0.0141 0.0376 0.0695
Giardia lamblia Cysteine protease 0.0277 0.0811 0.2212
Brugia malayi Animal haem peroxidase family protein 0.0236 0.0681 0.0678
Toxoplasma gondii centrin 0.0139 0.0369 0.068
Plasmodium vivax hypothetical protein, conserved 0.0141 0.0376 0.1059
Leishmania major calpain family cysteine protease-like protein 0.0255 0.0743 0.1372
Brugia malayi calcium-binding protein 0.0139 0.0369 0.0365
Echinococcus multilocularis histone deacetylase 3 0.009 0.021 0.0206
Plasmodium falciparum peptidase, putative 0.0215 0.0614 0.1743
Echinococcus granulosus proteasome prosome macropain subunit beta 0.007 0.0148 0.0144
Toxoplasma gondii histone deacetylase HDAC2 0.009 0.021 0.0385
Schistosoma mansoni survival motor neuron protein 0.0053 0.0093 0.0093
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.005 0.0079
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0231 0.0231
Trypanosoma cruzi cysteine peptidase, putative 0.1213 0.3822 0.3817
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0035 0.0035
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Giardia lamblia Cysteine protease 0.0277 0.0811 0.2212
Echinococcus granulosus proteasome prosome macropain 0.009 0.0212 0.0208
Trichomonas vaginalis calcium binding protein, putative 0.0139 0.0369 0.0988
Plasmodium vivax proteasome subunit beta type-1, putative 0.007 0.0148 0.0401
Brugia malayi Cathepsin L-like precursor 0.0337 0.1006 0.1002
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0062 0.0147
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0352 0.1055 0.1047
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0094 0.0223 0.0219
Trypanosoma cruzi cysteine peptidase, putative 0.1213 0.3822 0.3817
Brugia malayi fibroinase precursor 0.0277 0.0811 0.0807
Brugia malayi beta-lactamase 0.0035 0.0035 0.0031
Schistosoma mansoni notch 0.0026 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0059 0.0059
Plasmodium falciparum plasmepsin IX 0.0205 0.058 0.1644
Schistosoma mansoni cpg binding protein 0.0032 0.0025 0.0025
Loa Loa (eye worm) histone deacetylase 11 0.0043 0.0061 0.0057
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.007 0.0148 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0771 0.2401 0.6564
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.116 0.3653 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0255 0.0743 0.2015
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0004 0.000000018742
Plasmodium vivax plasmepsin IV, putative 0.0042 0.0058 0.0143
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0156 0.0423 0.042
Echinococcus multilocularis calpain 0.0868 0.2713 0.271
Giardia lamblia Cathepsin B precursor 0.116 0.3653 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0771 0.2401 0.6564
Loa Loa (eye worm) hypothetical protein 0.0043 0.0059 0.0055
Schistosoma mansoni cathepsin C 0.0277 0.0811 0.0811
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Schistosoma mansoni calpain-7 (C02 family) 0.0871 0.2722 0.2722
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1691 0.536 1
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0042 0.0058 0.0054
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0031
Toxoplasma gondii calcium-dependent protein kinase 0.0141 0.0376 0.0695
Brugia malayi prolyl oligopeptidase family protein 0.0706 0.2193 0.219
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Schistosoma mansoni cell polarity protein 0.0026 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0046 0.0071 0.0067
Toxoplasma gondii microneme protein MIC4 0.003 0.0018 0.0026
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0008 0.0004
Entamoeba histolytica hypothetical protein, conserved 0.0141 0.0376 0.1059
Leishmania major proteasome beta 5 subunit, putative 0.009 0.0212 0.0381
Schistosoma mansoni notch 0.0026 0.0004 0.0004
Brugia malayi hypothetical protein 0.0042 0.0058 0.0054
Onchocerca volvulus 0.0156 0.0423 0.0783
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.2059 0.6542 0.6541
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0698 0.2167 0.4601
Echinococcus multilocularis glycogen phosphorylase 0.0121 0.0312 0.0308
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1108 0.3485 0.9538
Brugia malayi calpain 5 0.0255 0.0743 0.0739
Echinococcus multilocularis transmembrane protease serine 3 0.0156 0.0423 0.042
Echinococcus multilocularis calcium uptake protein 1 0.0141 0.0376 0.0372
Trichomonas vaginalis histone deacetylase, putative 0.009 0.021 0.0555
Echinococcus multilocularis cathepsin L 0.0277 0.0811 0.0807
Schistosoma mansoni hypothetical protein 0.0156 0.0423 0.0423
Plasmodium falciparum proteasome subunit beta type-5 0.009 0.0212 0.0587
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0035 0.0031
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0059 0.0059
Loa Loa (eye worm) calpain 0.0868 0.2713 0.271
Entamoeba histolytica prolyl oligopeptidase family protein 0.0215 0.0614 0.1743
Brugia malayi Trypsin family protein 0.0156 0.0423 0.042
Echinococcus granulosus geminin 0.0183 0.0511 0.0507
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Toxoplasma gondii aspartyl protease ASP3 0.0205 0.058 0.1075
Onchocerca volvulus 0.1108 0.3485 0.6498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Giardia lamblia Cathepsin B precursor 0.116 0.3653 1
Giardia lamblia Histone deacetylase 0.009 0.021 0.0566
Trypanosoma brucei proteasome beta 6 subunit 0.007 0.0148 0.026
Plasmodium vivax proteasome subunit beta type-5, putative 0.009 0.0212 0.0587
Echinococcus multilocularis caspase 2 0.0156 0.0424 0.042
Trichomonas vaginalis calmodulin, putative 0.0142 0.038 0.102
Echinococcus multilocularis enteropeptidase 0.0156 0.0423 0.042
Echinococcus multilocularis inhibitor of apoptosis protein 0.0187 0.0522 0.0518
Leishmania major phospholipase c-like protein 0.0139 0.0369 0.0673
Loa Loa (eye worm) hypothetical protein 0.0277 0.0811 0.0807
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.5053
Brugia malayi EF hand family protein 0.0141 0.0376 0.0372
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0868 0.2713 0.5053
Echinococcus multilocularis geminin 0.0183 0.0511 0.0507
Echinococcus granulosus beta-adrenergic receptor kinase 0.0043 0.0059 0.0055
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0042 0.0058 0.0136
Loa Loa (eye worm) calpain family protein 1 0.2314 0.7363 0.7362
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Trichomonas vaginalis calpain, putative 0.0255 0.0743 0.2015
Echinococcus multilocularis cysteine protease 0.1108 0.3485 0.3482
Brugia malayi calpain 7 0.0868 0.2713 0.271
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0698 0.2167 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0255 0.0743 0.0735
Trypanosoma cruzi centrin-3 0.0142 0.038 0.0372
Echinococcus granulosus microtubule associated protein 2 0.1502 0.4752 0.475
Toxoplasma gondii cathepsin B 0.116 0.3653 0.6813
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0277 0.0811 0.0807
Schistosoma mansoni glycogen phosphorylase 0.0121 0.0312 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0277 0.0811 0.2203
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0215 0.0614 0.1132
Brugia malayi regulator of G-protein signaling rgs-7 0.0043 0.0059 0.0055
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0059 0.0055
Schistosoma mansoni glycogen phosphorylase 0.0121 0.0312 0.0312
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0018 0.0026
Echinococcus granulosus cathepsin l cysteine peptidase 0.1108 0.3485 0.3482
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0059 0.014
Loa Loa (eye worm) hypothetical protein 0.0137 0.0363 0.0359
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0277 0.0811 0.231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Loa Loa (eye worm) hypothetical protein 0.0094 0.0223 0.0219
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0212 0.056
Echinococcus multilocularis calmodulin 0.0139 0.0369 0.0365
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0056 0.0143
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0255 0.0743 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0139 0.0369 0.0673
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0014
Trichomonas vaginalis calmodulin, putative 0.0139 0.0369 0.0988
Loa Loa (eye worm) animal heme peroxidase 0.0236 0.0681 0.0678
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0381 0.0381
Mycobacterium ulcerans hypothetical protein 0.0288 0.0847 0.3807
Loa Loa (eye worm) hypothetical protein 0.0182 0.0507 0.0503
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.005 0.0121
Schistosoma mansoni ef hand domain family member A2 0.0139 0.0369 0.0369
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.009 0.0212 0.0208
Loa Loa (eye worm) hypothetical protein 0.0094 0.0223 0.0219
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0381 0.0377
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0344 0.0635
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.5053
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0026 0.0004 0.000000034978
Brugia malayi Cathepsin L-like cysteine proteinase 0.0771 0.2401 0.2398
Schistosoma mansoni calmodulin 0.0139 0.0369 0.0369
Schistosoma mansoni hypothetical protein 0.0053 0.0093 0.0093
Entamoeba histolytica cysteine proteinase, putative 0.0614 0.1895 0.5427
Trypanosoma brucei mitochondrial calcium uptake 1 0.0139 0.0369 0.0673
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0698 0.2167 0.4033
Entamoeba histolytica hypothetical protein 0.0277 0.0811 0.231
Entamoeba histolytica prolyl oligopeptidase family protein 0.0215 0.0614 0.1743
Loa Loa (eye worm) hypothetical protein 0.0168 0.0463 0.0459
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0344 0.1452
Giardia lamblia Glycogen phosphorylase 0.0121 0.0312 0.0844
Brugia malayi Cytochrome P450 family protein 0.0035 0.0036 0.0031
Trypanosoma cruzi oligopeptidase b 0.0698 0.2167 0.216
Onchocerca volvulus Peroxidase homolog 0.0236 0.0681 0.1265
Loa Loa (eye worm) hypothetical protein 0.0071 0.0149 0.0145
Entamoeba histolytica cysteine proteinase, putative 0.0771 0.2401 0.6882
Entamoeba histolytica calpain large subunit domain III containing protein 0.0613 0.1892 0.5419
Loa Loa (eye worm) hypothetical protein 0.0771 0.2401 0.2398
Loa Loa (eye worm) hypothetical protein 0.0139 0.0369 0.0365
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0352 0.1055 0.1955
Loa Loa (eye worm) hypothetical protein 0.0156 0.0423 0.042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.0811 0.2203
Onchocerca volvulus 0.0156 0.0423 0.0783
Trichomonas vaginalis peptide N-glycanase, putative 0.0288 0.0847 0.23
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0056 0.0138
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Schistosoma mansoni gabp alpha 0.007 0.0148 0.0148
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0036 0.0027
Schistosoma mansoni hypothetical protein 0.0156 0.0423 0.0423
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.042
Echinococcus granulosus expressed protein 0.0831 0.2595 0.2592
Brugia malayi Histone deacetylase 1 0.009 0.021 0.0206
Plasmodium vivax histone deacetylase 2, putative 0.0101 0.0246 0.0684
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Onchocerca volvulus 0.1108 0.3485 0.6498
Plasmodium vivax vivapain-1 0.0614 0.1895 0.5427
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.005 0.0042
Toxoplasma gondii histone deacetylase HDAC3 0.009 0.021 0.0385
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0014
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0183 0.0511 0.0511
Brugia malayi Histone deacetylase family protein 0.0101 0.0246 0.0242
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.0058 0.0143
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0344 0.0344
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1476 0.4668 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0277 0.0811 0.2203
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2314 0.7363 0.7363
Loa Loa (eye worm) hypothetical protein 0.0046 0.0071 0.0067
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0056 0.0131
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0706 0.2193 0.219
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0277 0.0811 0.231
Loa Loa (eye worm) blistered cuticle protein 3 0.0236 0.0681 0.0678
Schistosoma mansoni gamma-secretase subunit aph-1 0.0255 0.0743 0.0743
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0074 0.0074
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0056 0.0138
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0128 0.0231
Plasmodium vivax SET domain protein, putative 0.0096 0.0231 0.064
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0277 0.0811 0.231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.116 0.3653 0.681
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0277 0.0811 0.231
Loa Loa (eye worm) hypothetical protein 0.2314 0.7363 0.7362
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0255 0.0743 0.2015
Schistosoma mansoni calpain C (C02 family) 0.0868 0.2713 0.2713
Trichomonas vaginalis ap endonuclease, putative 0.004 0.005 0.0116
Toxoplasma gondii aspartyl protease ASP1 0.0042 0.0058 0.0101
Entamoeba histolytica proteasome subunit beta type 1, putative 0.007 0.0148 0.0401
Echinococcus granulosus cpg binding protein 0.0034 0.0031 0.0027
Trypanosoma brucei calmodulin, putative 0.0141 0.0376 0.0688
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0035 0.0027
Entamoeba histolytica cysteine protease, putative 0.0277 0.0811 0.231
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0255 0.0743 0.0735
Schistosoma mansoni calmodulin related calcium binding protein 0.0139 0.0369 0.0369
Loa Loa (eye worm) proteasome subunit beta type 1 0.007 0.0148 0.0144
Schistosoma mansoni ap endonuclease 0.004 0.005 0.005
Toxoplasma gondii aspartyl protease 0.0042 0.0058 0.0101
Schistosoma mansoni ets-related 0.0213 0.0608 0.0608
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0139 0.0369 0.1036
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0231 0.0227
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0059 0.0059
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0056 0.0052
Trichomonas vaginalis calcineurin B subunit, putative 0.0139 0.0369 0.0988
Plasmodium falciparum histone deacetylase, putative 0.0101 0.0246 0.0684
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0614 0.1895 0.1895
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0344 0.034
Schistosoma mansoni hypothetical protein 0.0139 0.0369 0.0369
Echinococcus multilocularis tumor protein p63 0.0376 0.1132 0.1128
Loa Loa (eye worm) trypsin family protein 0.0156 0.0423 0.042
Toxoplasma gondii histone deacetylase HDAC5 0.0044 0.0062 0.0108
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Echinococcus multilocularis acylamino acid releasing enzyme 0.0215 0.0614 0.061
Schistosoma mansoni cathepsin F (C01 family) 0.0771 0.2401 0.2401
Plasmodium vivax aspartyl protease, putative 0.0042 0.0058 0.0143
Toxoplasma gondii cathepsin CPC2 0.0277 0.0811 0.1507
Echinococcus granulosus prolyl endopeptidase 0.1691 0.536 0.5358
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.0212 0.0204
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0868 0.2713 0.2707
Loa Loa (eye worm) hypothetical protein 0.0156 0.0423 0.042
Schistosoma mansoni cathepsin F (C01 family) 0.1108 0.3485 0.3485
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0043 0.0059 0.0059
Brugia malayi Thioredoxin family protein 0.0288 0.0847 0.0843
Toxoplasma gondii subtilisin SUB12 0.003 0.0018 0.0026
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.0246 0.0238
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0059 0.0055
Loa Loa (eye worm) PXA domain-containing protein 0.0043 0.0059 0.0055
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Mycobacterium leprae Conserved hypothetical protein 0.0288 0.0847 0.3807
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Giardia lamblia Transglutaminase/protease, putative 0.0288 0.0847 0.2309
Plasmodium falciparum plasmepsin III 0.0042 0.0058 0.0143
Trypanosoma cruzi major cysteine proteinase, putative 0.0277 0.0811 0.0804
Schistosoma mansoni cpg binding protein 0.0034 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0139 0.0369 0.0988
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0369 0.0369
Onchocerca volvulus 0.0053 0.0093 0.0165
Trichomonas vaginalis calmodulin, putative 0.0139 0.0369 0.0988
Entamoeba histolytica prolyl oligopeptidase family protein 0.0215 0.0614 0.1743
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0043 0.0059 0.0055
Leishmania major histone deacetylase, putative 0.0101 0.0246 0.0444
Loa Loa (eye worm) hypothetical protein 0.0071 0.0149 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.2707
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0344 0.0344
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0061 0.0053
Echinococcus granulosus histone deacetylase 1 0.009 0.021 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0059 0.014
Brugia malayi prolyl oligopeptidase family protein 0.1691 0.536 0.5358
Leishmania major centrin, putative,caltractin, putative 0.0139 0.0369 0.0673
Schistosoma mansoni hypothetical protein 0.0139 0.0369 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0069 0.0144 0.014
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0255 0.0743 0.0735
Trypanosoma brucei calpain-like protein, putative 0.0868 0.2713 0.5053
Brugia malayi hypothetical protein 0.0043 0.0059 0.0055
Mycobacterium ulcerans putative transglutaminase-like protein 0.0288 0.0847 0.3807
Schistosoma mansoni neprilysin-2 (M13 family) 0.0047 0.0074 0.0074
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.005 0.0127
Giardia lamblia Alanyl dipeptidyl peptidase 0.0215 0.0614 0.1672
Trypanosoma cruzi histone deacetylase 1, putative 0.009 0.021 0.0202
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.0423
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0344 0.1452
Echinococcus multilocularis Glycosyl transferase, family 35 0.0121 0.0312 0.0308
Brugia malayi aspartic protease BmAsp-2, identical 0.0042 0.0058 0.0054
Loa Loa (eye worm) animal heme peroxidase 0.0236 0.0681 0.0678
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.0771 0.2401 0.2398
Schistosoma mansoni notch 0.0026 0.0005 0.0005
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0698 0.2167 0.216
Trypanosoma brucei prolyl endopeptidase 0.1691 0.536 1
Echinococcus granulosus histone deacetylase 0.0101 0.0246 0.0242
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Brugia malayi Histone deacetylase family protein 0.0101 0.0246 0.0242
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0035 0.0073
Brugia malayi Cytochrome P450 family protein 0.0058 0.0109 0.0105
Echinococcus granulosus calmodulin 0.0139 0.0369 0.0365
Echinococcus multilocularis Mastin 0.0156 0.0423 0.042
Brugia malayi aspartic protease BmAsp-1, identical 0.0042 0.0058 0.0054
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1691 0.536 0.5358
Trypanosoma brucei oligopeptidase b 0.0698 0.2167 0.4033
Schistosoma mansoni neprilysin 0.0024 0.0001 0.0001
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0062 0.0062
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.005 0.0079
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0026
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0277 0.0811 0.0811
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0277 0.0811 0.231
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.0059 0.0055
Echinococcus granulosus calpain 5 0.0868 0.2713 0.271
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0035 0.005
Trypanosoma brucei cysteine peptidase, putative 0.0255 0.0743 0.1372
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0255 0.0743 0.1379
Echinococcus multilocularis calumenin 0.0141 0.0376 0.0372
Echinococcus granulosus Mastin 0.0156 0.0423 0.042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Giardia lamblia Cathepsin L-like protease 0.0277 0.0811 0.2212
Echinococcus multilocularis glycoprotein Antigen 5 0.0156 0.0423 0.042
Brugia malayi cathepsin Z-like cysteine proteinase 0.0277 0.0811 0.0807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.0811 0.2203
Loa Loa (eye worm) cysteine protease 0.1108 0.3485 0.3482
Toxoplasma gondii hypothetical protein 0.0255 0.0743 0.1379
Leishmania major cathepsin L-like protease 0.1108 0.3485 0.6496
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Onchocerca volvulus Peroxidase homolog 0.0236 0.0681 0.1265
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0148 0.0139
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.009 0.0212 0.0587
Loa Loa (eye worm) hypothetical protein 0.0069 0.0144 0.014
Onchocerca volvulus Chorion peroxidase homolog 0.0236 0.0681 0.1265
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0352 0.1055 0.1055
Trypanosoma brucei Calpain-like protein CALP1.3 0.0255 0.0743 0.1372
Trichomonas vaginalis ap endonuclease, putative 0.004 0.005 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0255 0.0743 0.0735
Brugia malayi cathepsin F-like cysteine proteinase 0.0277 0.0811 0.0807
Trypanosoma brucei histone deacetylase 3 0.0101 0.0246 0.0444
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Echinococcus granulosus histone deacetylase 6 0.0101 0.0246 0.0242
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0698 0.2167 0.216
Echinococcus multilocularis cathepsin L cysteine protease 0.1108 0.3485 0.3482
Echinococcus granulosus endothelin converting enzyme 1 0.0094 0.0223 0.0219
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0277 0.0811 0.0807
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0706 0.2193 0.2193
Brugia malayi EF hand family protein 0.0139 0.0369 0.0365
Loa Loa (eye worm) hypothetical protein 0.0043 0.0059 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0277 0.0811 0.2203
Onchocerca volvulus 0.1108 0.3485 0.6498
Plasmodium falciparum plasmepsin I 0.0042 0.0058 0.0143
Trypanosoma cruzi conserved protein 0.0255 0.0743 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0277 0.0811 0.2203
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0148 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Echinococcus multilocularis calbindin 32 0.0141 0.0376 0.0372
Giardia lamblia Cathepsin B precursor 0.0277 0.0811 0.2212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Brugia malayi PXA domain containing protein 0.0043 0.0059 0.0055
Trichomonas vaginalis myosin light chain 1, putative 0.0139 0.0369 0.0988
Loa Loa (eye worm) hypothetical protein 0.0337 0.1006 0.1002
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0004
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.0212 0.0204
Brugia malayi Papain family cysteine protease containing protein 0.0614 0.1895 0.1892
Brugia malayi Cathepsin L-like precursor 0.0771 0.2401 0.2398
Giardia lamblia Cathepsin B precursor 0.0277 0.0811 0.2212
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0343 0.034
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1108 0.3485 0.3482
Brugia malayi Animal haem peroxidase family protein 0.0236 0.0681 0.0678
Trichomonas vaginalis calcium binding protein, putative 0.0142 0.038 0.102
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0141 0.0376 0.0376
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0215 0.0614 0.0614
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0255 0.0743 0.0739
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Giardia lamblia Hypothetical protein 0.0288 0.0847 0.2309
Plasmodium falciparum plasmepsin VIII, putative 0.0042 0.0058 0.0143
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0056 0.0052
Echinococcus multilocularis calpain A 0.2455 0.7817 0.7816
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0026
Toxoplasma gondii histone deacetylase HDAC1 0.0101 0.0246 0.0452
Trypanosoma cruzi cysteine peptidase, putative 0.0614 0.1895 0.1888
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0036 0.0027
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0036 0.0031
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.0423 0.0423
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Leishmania major cathepsin L-like protease 0.1213 0.3822 0.7125
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Giardia lamblia Proteasome subunit beta type 5 precursor 0.009 0.0212 0.0571
Echinococcus granulosus peroxidasin 0.0236 0.0681 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0059 0.0059
Echinococcus granulosus apoptotic protease activating factor 1 0.0139 0.0369 0.0365
Echinococcus granulosus tissue type plasminogen activator 0.0046 0.0071 0.0067
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0255 0.0743 0.0735
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Trypanosoma brucei histone deacetylase 2 0.0043 0.0061 0.0099
Plasmodium vivax unspecified product 0.0277 0.0811 0.231
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0277 0.0811 0.231
Loa Loa (eye worm) hypothetical protein 0.1702 0.5393 0.5391
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0056 0.0131
Loa Loa (eye worm) programmed cell death protein 6 0.0141 0.0376 0.0372
Trichomonas vaginalis calcium binding proteins, putative 0.0139 0.0369 0.0988
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0042 0.0058 0.0054
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0056 0.0048
Loa Loa (eye worm) hypothetical protein 0.0064 0.0127 0.0123
Onchocerca volvulus 0.0236 0.0681 0.1265
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0868 0.2713 0.2707
Schistosoma mansoni hypothetical protein 0.0255 0.0743 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0139 0.0369 0.0988
Loa Loa (eye worm) hypothetical protein 0.0771 0.2401 0.2398
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0036 0.0002
Onchocerca volvulus 0.0156 0.0423 0.0783
Echinococcus multilocularis glycogen phosphorylase 0.0121 0.0312 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0139 0.0369 0.0988
Trypanosoma brucei protein I/6 0.0139 0.0369 0.0673
Onchocerca volvulus 0.0046 0.0071 0.0125
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0215 0.0614 0.0614
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0035 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0059 0.014
Echinococcus multilocularis histone deacetylase 1 0.009 0.021 0.0206
Trichomonas vaginalis centrin, putative 0.0139 0.0369 0.0988
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0706 0.2193 0.4087
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0062 0.0058
Plasmodium falciparum serine repeat antigen 4 0.0277 0.0811 0.231
Loa Loa (eye worm) hypothetical protein 0.0139 0.0369 0.0365
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0215 0.0614 0.1662
Leishmania major calmodulin-like protein 0.0139 0.0369 0.0673
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0868 0.2713 0.2707
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0014
Trypanosoma brucei cysteine peptidase C (CPC) 0.116 0.3653 0.681
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Plasmodium falciparum proteasome subunit beta type-1, putative 0.007 0.0148 0.0401
Brugia malayi Cathepsin L-like precursor 0.1108 0.3485 0.3482
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.005 0.0121
Echinococcus multilocularis histone deacetylase 0.0101 0.0246 0.0242
Leishmania major hypothetical protein, conserved 0.0035 0.0035 0.005
Giardia lamblia Cathepsin L precursor 0.0277 0.0811 0.2212
Toxoplasma gondii troponin c, isotype gamma, putative 0.0139 0.0369 0.068
Onchocerca volvulus 0.003 0.0018 0.0026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Loa Loa (eye worm) hypothetical protein 0.0156 0.0423 0.042
Schistosoma mansoni peroxidasin 0.0236 0.0681 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0277 0.0811 0.2203
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0096 0.0231 0.0227
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0231 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0277 0.0811 0.2203
Giardia lamblia Cathepsin L-like protease 0.0277 0.0811 0.2212
Schistosoma mansoni histone deacetylase hda2 0.0107 0.0266 0.0266
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0255 0.0743 0.2015
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.1108 0.3485 0.3482
Plasmodium falciparum plasmepsin VII 0.0042 0.0058 0.0143
Onchocerca volvulus 0.0042 0.0056 0.0097
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0014
Echinococcus multilocularis calmodulin 0.0139 0.0369 0.0365
Brugia malayi programmed cell death protein 6 0.0139 0.0369 0.0365
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0054
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus granulosus caspase 2 0.0156 0.0424 0.042
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0776 0.2417 0.2417
Loa Loa (eye worm) hypothetical protein 0.0187 0.0522 0.0518
Plasmodium falciparum serine repeat antigen 2 0.0277 0.0811 0.231
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0156 0.0423 0.0423
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Leishmania major hypothetical protein, unknown function 0.0255 0.0743 0.1372
Brugia malayi beta-lactamase family protein 0.0035 0.0035 0.0031
Trypanosoma cruzi cysteine proteinase, putative 0.0614 0.1895 0.1888
Brugia malayi carbohydrate phosphorylase 0.0121 0.0312 0.0308
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0059 0.0059
Entamoeba histolytica calmodulin, putative 0.0139 0.0369 0.1036
Echinococcus multilocularis tissue type plasminogen activator 0.0046 0.0071 0.0067
Echinococcus granulosus EF hand domain containing family member A2 0.0139 0.0369 0.0365
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0139 0.0369 0.0361
Plasmodium vivax unspecified product 0.0614 0.1895 0.5427
Echinococcus multilocularis gamma secretase subunit aph 1 0.0255 0.0743 0.0739
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Entamoeba histolytica grainin 2 0.0142 0.038 0.1069
Brugia malayi hypothetical protein 0.0137 0.0363 0.0359
Plasmodium falciparum serine repeat antigen 7 0.0277 0.0811 0.231
Loa Loa (eye worm) fibroinase 0.1108 0.3485 0.3482
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0277 0.0811 0.0811
Trichomonas vaginalis histone deacetylase, putative 0.009 0.021 0.0555
Echinococcus multilocularis EF hand domain containing family member A2 0.0139 0.0369 0.0365
Brugia malayi Fli-1 protein 0.0213 0.0608 0.0604
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0031
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0187 0.0522 0.0522
Echinococcus multilocularis expressed protein 0.0831 0.2595 0.2592
Trypanosoma cruzi kinesin, putative 0.0613 0.1892 0.1885
Entamoeba histolytica cysteine proteinase, putative 0.1108 0.3485 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.005 0.0042
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0381 0.0377
Plasmodium falciparum plasmepsin II 0.0042 0.0058 0.0143
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0698 0.2167 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0215 0.0614 0.1662
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Toxoplasma gondii exonuclease III APE 0.004 0.005 0.0087
Leishmania major centrin, putative 0.0139 0.0369 0.0673
Brugia malayi hypothetical protein 0.0156 0.0423 0.042
Entamoeba histolytica cysteine protease, putative 0.0277 0.0811 0.231
Echinococcus granulosus enteropeptidase 0.0156 0.0423 0.042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0614 0.1895 0.5177
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0042 0.0058 0.0101
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Brugia malayi Eukaryotic aspartyl protease family protein 0.0042 0.0058 0.0054
Echinococcus granulosus centrin 2 0.0139 0.0369 0.0365
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0139 0.0369 0.0673
Echinococcus granulosus transmembrane protease serine 3 0.0156 0.0423 0.042
Echinococcus granulosus Transglutaminase 0.0288 0.0847 0.0843
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0381 0.0377
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0062 0.01
Onchocerca volvulus 0.0046 0.0071 0.0124
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0035 0.0073
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0614 0.1895 0.1888
Loa Loa (eye worm) hypothetical protein 0.0156 0.0423 0.042
Echinococcus granulosus Dipeptidyl peptidase 9 0.0352 0.1055 0.1051
Loa Loa (eye worm) hypothetical protein 0.0156 0.0424 0.042
Giardia lamblia Cathepsin B precursor 0.116 0.3653 1
Mycobacterium ulcerans hypothetical protein 0.0156 0.0423 0.1822
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.116 0.3653 0.3653
Trypanosoma cruzi cysteine peptidase, putative 0.0337 0.1006 0.0998
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0018 0.0026
Chlamydia trachomatis glycogen phosphorylase 0.0121 0.0312 0.5
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0242 0.0437
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0062 0.0108
Schistosoma mansoni hypothetical protein 0.0455 0.1385 0.1385
Schistosoma mansoni cathepsin D (A01 family) 0.0232 0.0667 0.0667
Loa Loa (eye worm) EF hand family protein 0.0139 0.0369 0.0365
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0337 0.1006 0.1002
Plasmodium vivax aspartyl protease, putative 0.0205 0.058 0.1644
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0139 0.0369 0.0988
Toxoplasma gondii hypothetical protein 0.0215 0.0614 0.1139
Mycobacterium leprae probable zinc metalloprotease 0.0094 0.0223 0.0881
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0277 0.0811 0.231
Onchocerca volvulus 0.0288 0.0847 0.1573
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Onchocerca volvulus Prolyl endopeptidase homolog 0.1691 0.536 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0036 0.0031
Onchocerca volvulus 0.003 0.0018 0.0026
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.0246 0.0238
Mycobacterium leprae proteasome (beta subunit) PrcB 0.009 0.0212 0.0832
Onchocerca volvulus Dual oxidase homolog 0.0236 0.0681 0.1265
Mycobacterium leprae Conserved hypothetical protein 0.0288 0.0847 0.3807
Echinococcus multilocularis calpain 5 0.0868 0.2713 0.271
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0043 0.0059 0.014
Schistosoma mansoni histone deacetylase 4 5 0.0101 0.0246 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.0811 0.2203
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0061 0.0053
Brugia malayi Trypsin-like protease protein 5 0.0156 0.0423 0.042
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0255 0.0743 0.0735
Echinococcus granulosus histone deacetylase 6 0.0107 0.0266 0.0262
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0187 0.0522 0.0518
Loa Loa (eye worm) hypothetical protein 0.0277 0.0811 0.0807
Entamoeba histolytica calmodulin, putative 0.0139 0.0369 0.1036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.007 0.0148 0.026
Echinococcus multilocularis Regulator of G protein signaling 20 0.0043 0.0059 0.0055
Schistosoma mansoni slit 0.0026 0.0004 0.0004
Onchocerca volvulus 0.0035 0.0035 0.0058
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0148 0.0144
Entamoeba histolytica histone deacetylase, putative 0.009 0.021 0.0582
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0056 0.0131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Loa Loa (eye worm) hypothetical protein 0.0046 0.0071 0.0067
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Plasmodium vivax hypothetical protein, conserved 0.0215 0.0614 0.1743
Loa Loa (eye worm) hypothetical protein 0.0337 0.1006 0.1002
Brugia malayi Cathepsin L-like precursor 0.1108 0.3485 0.3482
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0026
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0014
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0255 0.0743 0.2015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0059 0.0055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0255 0.0743 0.0735
Trypanosoma brucei centrin, putative 0.0139 0.0369 0.0673
Giardia lamblia Hypothetical protein 0.0277 0.0811 0.2212
Brugia malayi Papain family cysteine protease containing protein 0.0614 0.1895 0.1892
Echinococcus multilocularis proteasome (prosome, macropain) 0.009 0.0212 0.0208
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0277 0.0811 0.0811
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Toxoplasma gondii centrin, putative 0.0139 0.0369 0.068
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Leishmania major calpain protease-like protein 0.0255 0.0743 0.1372
Giardia lamblia Cathepsin B precursor 0.0277 0.0811 0.2212
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0004
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0062 0.0054
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.2707
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0255 0.0743 0.1372
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0352 0.1055 0.1051
Schistosoma mansoni centrin-related 0.0139 0.0369 0.0369
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0091 0.0237
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0035 0.0031
Echinococcus multilocularis neuronal calcium sensor 0.0139 0.0369 0.0365
Echinococcus granulosus glycoprotein Antigen 5 0.0156 0.0423 0.042
Plasmodium falciparum centrin-1 0.0139 0.0369 0.1036
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.000000018742
Trypanosoma brucei Component of motile flagella 41 0.0139 0.0369 0.0673
Mycobacterium ulcerans transglutaminase family protein 0.0288 0.0847 0.3807
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0369 0.0369
Leishmania major cathepsin L-like protease 0.1213 0.3822 0.7125
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0035 0.0031
Trichomonas vaginalis calmodulin, putative 0.0139 0.0369 0.0988
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Giardia lamblia Alanyl dipeptidyl peptidase 0.0215 0.0614 0.1672
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1108 0.3485 0.3482
Plasmodium falciparum cysteine proteinase falcipain 1 0.0614 0.1895 0.5427
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0277 0.0811 0.231
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0054
Echinococcus multilocularis endothelin converting enzyme 1 0.0094 0.0223 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Leishmania major cathepsin L-like protease 0.1108 0.3485 0.6496
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0231 0.0231
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0614 0.0606
Giardia lamblia Proteasome subunit beta type 1 0.007 0.0148 0.0393
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0059 0.0055
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Onchocerca volvulus Histone deacetylase 10 homolog 0.0043 0.0061 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Trypanosoma brucei Calpain-like protein 1.1 0.0255 0.0743 0.1372
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0059 0.0055
Leishmania major kinesin, putative 0.0613 0.1892 0.352
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0206
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1108 0.3485 1
Loa Loa (eye worm) histone deacetylase 3 0.009 0.021 0.0206
Brugia malayi Papain family cysteine protease containing protein 0.0277 0.0811 0.0807
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0381 0.0377
Loa Loa (eye worm) prolyl oligopeptidase 0.0215 0.0614 0.061
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0014
Echinococcus granulosus cathepsin l1 0.0771 0.2401 0.2398
Echinococcus multilocularis cathepsin L cysteine protease 0.1108 0.3485 0.3482
Onchocerca volvulus 0.0168 0.0463 0.0857
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.005 0.0033
Brugia malayi Cathepsin L-like precursor 0.1108 0.3485 0.3482
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Trypanosoma brucei prolyl oligopeptidase, putative 0.0698 0.2167 0.4033
Schistosoma mansoni glycogen phosphorylase 0.0052 0.0091 0.0091
Onchocerca volvulus 0.0035 0.0035 0.0058
Onchocerca volvulus 0.003 0.0018 0.0026
Loa Loa (eye worm) prolyl oligopeptidase 0.0706 0.2193 0.219
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0139 0.0369 0.0361
Plasmodium falciparum cysteine repeat modular protein 1 0.0046 0.0071 0.0179
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0059 0.0055
Onchocerca volvulus 0.003 0.0018 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0059 0.014
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0215 0.0614 0.1743
Loa Loa (eye worm) calpain family protein 1 0.1702 0.5393 0.5391
Schistosoma mansoni microtubule-associated protein tau 0.1502 0.4752 0.4752
Echinococcus granulosus calcium uptake protein 1 0.0141 0.0376 0.0372
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.005 0.0046
Entamoeba histolytica cysteine proteinase, putative 0.0614 0.1895 0.5427
Leishmania major cytochrome p450-like protein 0.0035 0.0036 0.0051
Brugia malayi hypothetical protein 0.0139 0.0369 0.0365
Loa Loa (eye worm) hypothetical protein 0.0156 0.0423 0.042
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0071 0.0067
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0148 0.0144
Trichomonas vaginalis calmodulin, putative 0.0141 0.0376 0.101
Echinococcus multilocularis programmed cell death protein 0.0142 0.038 0.0376
Trypanosoma brucei histone deacetylase 1 0.009 0.021 0.0378
Onchocerca volvulus Cathepsin L homolog 0.1108 0.3485 0.6498
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0008 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0059 0.0059
Leishmania major hypothetical protein, conserved 0.0046 0.0071 0.0116
Loa Loa (eye worm) hypothetical protein 0.1446 0.4572 0.457
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0004
Trypanosoma cruzi I/6 autoantigen, putative 0.0139 0.0369 0.0361
Entamoeba histolytica hypothetical protein 0.0043 0.0059 0.0147
Entamoeba histolytica calpain family cysteine protease, putative 0.0255 0.0743 0.2112
Brugia malayi Papain family cysteine protease containing protein 0.0277 0.0811 0.0807
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0868 0.2713 0.2707
Brugia malayi hypothetical protein 0.0043 0.0059 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0151 0.0151
Plasmodium falciparum serine repeat antigen 3 0.0277 0.0811 0.231
Brugia malayi cathepsin F-like cysteine proteinase 0.0337 0.1006 0.1002
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0277 0.0811 0.2212
Echinococcus granulosus dnaJ subfamily B 0.0455 0.1385 0.1382
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Onchocerca volvulus 0.0096 0.0231 0.0423
Toxoplasma gondii microneme protein MIC17A 0.003 0.0018 0.0026
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0056 0.0131
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0381 0.0381
Echinococcus granulosus glycogen phosphorylase 0.0121 0.0312 0.0308
Echinococcus granulosus cathepsin L cysteine proteinase 0.1108 0.3485 0.3482
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0255 0.0743 0.1372
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.0059 0.0055
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0277 0.0811 0.231
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0344 0.034
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0042 0.0058 0.0054
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0352 0.1055 0.1047
Entamoeba histolytica hypothetical protein 0.0043 0.0059 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0614 0.1895 0.5177
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0868 0.2713 0.5053
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0255 0.0743 0.0735
Trypanosoma cruzi prolyl endopeptidase 0.1691 0.536 0.5356
Loa Loa (eye worm) calmodulin-like protein 0.0139 0.0369 0.0365
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Echinococcus granulosus Regulator of G protein signaling 20 0.0043 0.0059 0.0055
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0522 0.0518
Brugia malayi Ets-domain containing protein 0.007 0.0148 0.0144
Echinococcus granulosus cathepsin L 0.0277 0.0811 0.0807
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0277 0.0811 0.0811
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0156 0.0423 0.042
Schistosoma mansoni caspase-7 (C14 family) 0.0156 0.0424 0.0424
Trypanosoma brucei proteasome subunit beta type-5, putative 0.009 0.0212 0.0381
Toxoplasma gondii microneme protein MIC17B 0.003 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.0052
Brugia malayi Kringle domain containing protein 0.0046 0.0071 0.0067
Echinococcus multilocularis regulator of G protein signaling 0.0043 0.0059 0.0055
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Brugia malayi MH2 domain containing protein 0.0131 0.0343 0.034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Toxoplasma gondii peptidase family M13 protein 0.0094 0.0223 0.0408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.0811 0.2203
Leishmania major cathepsin L-like protease 0.1108 0.3485 0.6496
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.009 0.0212 0.0383
Giardia lamblia Cathepsin B precursor 0.0277 0.0811 0.2212
Onchocerca volvulus 0.003 0.0018 0.0026
Echinococcus granulosus calpain 7 C02 family 0.0868 0.2713 0.271
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0074 0.0074
Trichomonas vaginalis histone deacetylase, putative 0.009 0.021 0.0555
Brugia malayi notch-like transmembrane receptor 0.0026 0.0004 0.000000018742
Schistosoma mansoni histone deacetylase 4 5 0.0101 0.0246 0.0246
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0014
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0242 0.0234
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0255 0.0743 0.2015
Brugia malayi proteasome subunit beta type 2 0.0043 0.0062 0.0058
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0144 0.014
Trypanosoma brucei kinesin, putative 0.0613 0.1892 0.352
Schistosoma mansoni notch 0.0026 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0144 0.014
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0056 0.0138
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.0423 0.0423
Plasmodium vivax vivapain-3 0.0614 0.1895 0.5427
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0062 0.0154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1213 0.3822 0.7125
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.0052
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.0058 0.0058
Brugia malayi calpain family protein 1 0.2314 0.7363 0.7362
Trichomonas vaginalis calmodulin-2, putative 0.0139 0.0369 0.0988
Toxoplasma gondii hypothetical protein 0.003 0.0018 0.0026
Trypanosoma cruzi centrin, putative 0.0142 0.038 0.0372
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0059 0.0055
Trypanosoma cruzi major cysteine proteinase, putative 0.0381 0.1148 0.1141
Brugia malayi Cathepsin L-like precursor 0.1108 0.3485 0.3482
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0614 0.1895 0.1895
Loa Loa (eye worm) hypothetical protein 0.0043 0.0061 0.0057
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0148 0.0382
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0706 0.2193 0.219
Onchocerca volvulus Peroxidasin homolog 0.0236 0.0681 0.1265
Entamoeba histolytica cysteine protease, putative 0.0277 0.0811 0.231
Leishmania major histone deacetylase, putative 0.009 0.021 0.0378
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0035 0.0073
Echinococcus granulosus acylamino acid releasing enzyme 0.0215 0.0614 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0743 0.2015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Onchocerca volvulus 0.003 0.0018 0.0026
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.005 0.5
Brugia malayi Pre-SET motif family protein 0.0665 0.2061 0.2058
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0139 0.0369 0.0365
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0056 0.0048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.0735
Trypanosoma brucei Calpain-like protein 2 0.0255 0.0743 0.1372
Leishmania major protein kinase, putative 0.0139 0.0369 0.0673
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0071 0.0062
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0035 0.0073
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0369 0.0369
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0062 0.0147
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0059 0.0055
Giardia lamblia Cysteine protease 0.0277 0.0811 0.2212
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0381 0.0381
Echinococcus granulosus tumor protein p63 0.0376 0.1132 0.1128
Leishmania major calmodulin-like protein 0.0139 0.0369 0.0673
Onchocerca volvulus 0.1108 0.3485 0.6498
Loa Loa (eye worm) hypothetical protein 0.0277 0.0811 0.0807
Schistosoma mansoni hypothetical protein 0.0288 0.0847 0.0847
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0148 0.0144
Brugia malayi prolyl oligopeptidase family protein 0.0352 0.1055 0.1051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus granulosus calumenin 0.0141 0.0376 0.0372
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0277 0.0811 0.2203
Plasmodium falciparum histone deacetylase 2 0.0101 0.0246 0.0684
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0056 0.0131
Schistosoma mansoni septate junction protein 0.0026 0.0004 0.0004
Giardia lamblia Cathepsin L precursor 0.0277 0.0811 0.2212
Trichomonas vaginalis histone deacetylase, putative 0.009 0.021 0.0555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus multilocularis survival motor neuron protein 1 0.026 0.0759 0.0755
Plasmodium falciparum histone deacetylase 1 0.009 0.021 0.0582
Trypanosoma brucei histone deacetylase 4 0.0101 0.0246 0.0444
Loa Loa (eye worm) hypothetical protein 0.0215 0.0614 0.061
Loa Loa (eye worm) hypothetical protein 0.0071 0.0149 0.0145
Schistosoma mansoni centrin 0.0139 0.0369 0.0369
Onchocerca volvulus 0.0277 0.0811 0.1507
Plasmodium vivax serine-repeat antigen (SERA) 0.0277 0.0811 0.231
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0277 0.0811 0.0811
Leishmania major histone deacetylase, putative 0.0101 0.0246 0.0444
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0059 0.0055
Trichomonas vaginalis centrin, putative 0.0139 0.0369 0.0988
Echinococcus multilocularis peroxidasin 0.0236 0.0681 0.0678
Brugia malayi Cathepsin L-like precursor 0.1108 0.3485 0.3482
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0776 0.2417 0.2414
Trypanosoma brucei calpain-like protein, putative 0.0868 0.2713 0.5053
Onchocerca volvulus 0.0156 0.0423 0.0783
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0056 0.0048
Echinococcus granulosus histone deacetylase 7 0.0101 0.0246 0.0242
Plasmodium falciparum plasmepsin VI 0.0042 0.0058 0.0143
Loa Loa (eye worm) hypothetical protein 0.026 0.0759 0.0755
Loa Loa (eye worm) calpain 5 0.0613 0.1892 0.1889
Echinococcus multilocularis histone deacetylase 6 0.0107 0.0266 0.0262
Entamoeba histolytica cysteine protease, putative 0.0614 0.1895 0.5427
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0035 0.0031
Leishmania major calmodulin, putative 0.0139 0.0369 0.0673
Brugia malayi Cathepsin L-like precursor 0.1108 0.3485 0.3482
Brugia malayi Animal haem peroxidase family protein 0.0236 0.0681 0.0678
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0059 0.0055
Echinococcus granulosus calpain A 0.2455 0.7817 0.7816
Onchocerca volvulus 0.0187 0.0522 0.0967
Brugia malayi cathepsin L-like cysteine proteinase 0.0277 0.0811 0.0807
Leishmania major hypothetical protein, conserved 0.0255 0.0743 0.1372
Schistosoma mansoni notch 0.0026 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.0103
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0381 0.0377
Toxoplasma gondii kringle domain-containing protein 0.0046 0.0071 0.0124
Trichomonas vaginalis glycogen phosphorylase, putative 0.0121 0.0312 0.0833
Schistosoma mansoni memapsin-2 (A01 family) 0.0503 0.1539 0.1539
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0277 0.0811 0.2212
Loa Loa (eye worm) hypothetical protein 0.0356 0.1066 0.1062
Loa Loa (eye worm) hypothetical protein 0.0236 0.0681 0.0678
Trypanosoma cruzi calmodulin, putative 0.0139 0.0369 0.0361
Schistosoma mansoni histone deacetylase 0.009 0.021 0.021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0665 0.2061 0.2058
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0091 0.0237
Toxoplasma gondii cathepsin CPC1 0.0277 0.0811 0.1507
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0277 0.0811 0.0811
Brugia malayi calpain 5 0.0613 0.1892 0.1889
Leishmania major oligopeptidase b 0.0698 0.2167 0.4033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0255 0.0743 0.1372
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2453 0.7809 0.7808
Loa Loa (eye worm) calpain D 0.0255 0.0743 0.0739
Leishmania major C-8 sterol isomerase-like protein 0.0356 0.1066 0.1976
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0231 0.0423
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0061 0.0061
Echinococcus multilocularis beta adrenergic receptor kinase 0.0043 0.0059 0.0055
Onchocerca volvulus Peroxidasin homolog 0.0236 0.0681 0.1265
Onchocerca volvulus 0.003 0.0018 0.0026
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.005 0.0072
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0356 0.1066 0.1058
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0255 0.0743 0.1372
Plasmodium falciparum serine repeat antigen 8 0.0277 0.0811 0.231
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0277 0.0811 0.231
Entamoeba histolytica cysteine proteinase, putative 0.0614 0.1895 0.5427
Onchocerca volvulus 0.003 0.0018 0.0026
Brugia malayi Trypsin family protein 0.0156 0.0423 0.042
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1691 0.536 0.536
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0056 0.0056
Trypanosoma brucei hypothetical protein 0.0255 0.0743 0.1372
Echinococcus granulosus programmed cell death protein 0.0142 0.038 0.0376
Brugia malayi CXXC zinc finger family protein 0.0032 0.0025 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1108 0.3485 0.9538
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.005 0.0046
Entamoeba histolytica hypothetical protein 0.0043 0.0059 0.0147
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0062 0.0058
Leishmania major hypothetical protein, conserved 0.0141 0.0376 0.0688
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.005 0.0046
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0062 0.0154
Brugia malayi Peptidase family M13 containing protein 0.0094 0.0223 0.0219
Giardia lamblia Serine peptidase, putative 0.0042 0.0056 0.0143
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0014

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.