Detailed information for compound 1529337

Basic information

Technical information
  • TDR Targets ID: 1529337
  • Name: 4-[4-(2-fluorophenyl)piperazin-1-yl]-6,7,8,9- tetrahydropurino[9,8-a]pyridine
  • MW: 352.409 | Formula: C19H21FN6
  • H donors: 0 H acceptors: 3 LogP: 2.92 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccccc1N1CCN(CC1)c1ncnc2c1nc1n2CCCC1
  • InChi: 1S/C19H21FN6/c20-14-5-1-2-6-15(14)24-9-11-25(12-10-24)18-17-19(22-13-21-18)26-8-4-3-7-16(26)23-17/h1-2,5-6,13H,3-4,7-12H2
  • InChiKey: OYHVNAMTYHLDAX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[4-(2-fluorophenyl)-1-piperazinyl]-6,7,8,9-tetrahydropurino[9,8-a]pyridine
  • E715-0982
  • NCGC00124723-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0491 0.2556 0.2556
Schistosoma mansoni regulator of G protein signaling 0.004 0.0064 0.0064
Mycobacterium ulcerans hypothetical protein 0.0284 0.1409 0.334
Leishmania major cathepsin L-like protease 0.1011 0.5423 0.5411
Echinococcus granulosus histone deacetylase 3 0.0088 0.0333 0.0325
Schistosoma mansoni regulator of G protein signaling 0.004 0.0064 0.0064
Giardia lamblia Cathepsin L precursor 0.0203 0.0966 0.2781
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0914 0.4886 1
Schistosoma mansoni cathepsin F (C01 family) 0.0626 0.3297 0.3297
Loa Loa (eye worm) hypothetical protein 0.0104 0.0421 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Brugia malayi MH2 domain containing protein 0.0126 0.0539 0.0539
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Schistosoma mansoni hypothetical protein 0.0049 0.0114 0.0114
Plasmodium falciparum cysteine proteinase falcipain 3 0.0914 0.4886 1
Trypanosoma cruzi hypothetical protein, conserved 0.027 0.1332 0.131
Schistosoma mansoni Mername-AA248 (C02 family) 0.0534 0.279 0.279
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0064 0.0064
Plasmodium vivax SET domain protein, putative 0.0061 0.0184 0.0245
Schistosoma mansoni calpain-2 (C02 family) 0.016 0.0731 0.0731
Leishmania major calcineurin B subunit, putative 0.0087 0.0324 0.0298
Trypanosoma brucei centrin-3 0.0087 0.0324 0.0298
Onchocerca volvulus 0.0087 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0092 0.0354 0.0354
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.016 0.0731 0.0706
Entamoeba histolytica cysteine proteinase 2 0.0491 0.2556 0.5167
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1023 0.5488 0.5488
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Schistosoma mansoni hypothetical protein 0.0345 0.175 0.175
Echinococcus granulosus neurocalcin 0.0087 0.0324 0.0315
Giardia lamblia Cathepsin B precursor 0.0203 0.0966 0.2781
Trypanosoma cruzi oligopeptidase b 0.0784 0.4168 0.4152
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Schistosoma mansoni neuronal calcium sensor 0.0087 0.0324 0.0324
Onchocerca volvulus Legumain homolog 0.045 0.2326 0.2326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.027 0.1332 0.263
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0064 0.0064
Plasmodium falciparum serine repeat antigen 4 0.0203 0.0966 0.1869
Leishmania major i/6 autoantigen-like protein 0.0087 0.0324 0.0298
Echinococcus granulosus calpain 5 0.0534 0.279 0.2784
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0966 0.1871
Loa Loa (eye worm) hypothetical protein 0.0203 0.0966 0.0966
Giardia lamblia Cathepsin L-like protease 0.0203 0.0966 0.2781
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.0966 0.0966
Schistosoma mansoni centrin-related 0.0087 0.0324 0.0324
Echinococcus granulosus cathepsin L 0.0491 0.2556 0.2549
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0491 0.2556 0.2556
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0064
Trypanosoma cruzi 20S proteasome subunit 0.004 0.0066 0.004
Schistosoma mansoni hypothetical protein 0.0168 0.077 0.077
Leishmania major cathepsin L-like protease 0.0914 0.4886 0.4873
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.016 0.0731 0.1382
Trypanosoma brucei kinesin, putative 0.0373 0.1905 0.1883
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0034 0.0033 0.0025
Entamoeba histolytica cysteine proteinase, putative 0.0914 0.4886 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0914 0.4886 1
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0087 0.0324 0.0538
Entamoeba histolytica cysteine protease, putative 0.0203 0.0966 0.1871
Echinococcus granulosus proteasome prosome macropain subunit beta 0.004 0.0066 0.0057
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Echinococcus granulosus Dipeptidyl peptidase 9 0.0663 0.3499 0.3494
Leishmania major C-8 sterol isomerase-like protein 0.036 0.1828 0.1807
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0063 0.0191 0.0126
Echinococcus multilocularis histone deacetylase 6 0.0106 0.0428 0.0419
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0393 0.0368
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0203 0.0966 0.0966
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.0966 0.0966
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Loa Loa (eye worm) EF hand family protein 0.0087 0.0324 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0203 0.0966 0.1871
Echinococcus granulosus cathepsin b 0.1574 0.8527 0.8526
Echinococcus granulosus axis inhibition protein axin 0.004 0.0064 0.0055
Entamoeba histolytica prolyl oligopeptidase family protein 0.027 0.1332 0.263
Loa Loa (eye worm) hypothetical protein 0.027 0.1332 0.1332
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0526 0.1208
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.045 0.2326 0.469
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0083 0.0303 0.0495
Brugia malayi prolyl oligopeptidase family protein 0.027 0.1332 0.1332
Mycobacterium tuberculosis Probable peptidase 0.0784 0.4168 0.4707
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0966 0.1871
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0064 0.0201 0.0136
Toxoplasma gondii cathepsin CPL 0.0914 0.4886 0.4853
Echinococcus granulosus calbindin 32 0.0088 0.0333 0.0324
Giardia lamblia Cathepsin B precursor 0.0203 0.0966 0.2781
Echinococcus granulosus dnaJ subfamily B 0.0399 0.2047 0.204
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.0966 0.0966
Mycobacterium tuberculosis Hypothetical protein 0.0284 0.1409 0.1348
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0064 0.0064
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0184 0.0175
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0491 0.2556 0.5167
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0087 0.0324 0.0298
Echinococcus multilocularis microtubule associated protein 2 0.1427 0.7718 0.7716
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0033
Echinococcus multilocularis cysteine protease 0.0914 0.4886 0.4882
Echinococcus multilocularis glycoprotein Antigen 5 0.0034 0.0033 0.0025
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0784 0.4168 0.4152
Schistosoma mansoni hypothetical protein 0.0284 0.1409 0.1409
Loa Loa (eye worm) hypothetical protein 0.0175 0.0811 0.0811
Toxoplasma gondii centrin 0.0087 0.0324 0.026
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Plasmodium falciparum histone deacetylase 1 0.0088 0.0333 0.0555
Echinococcus multilocularis calbindin 32 0.0088 0.0333 0.0324
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1502 0.8129 0.8128
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0097 0.0097
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0333 0.0558
Echinococcus granulosus transmembrane protease serine 3 0.0034 0.0033 0.0025
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0064 0.0064
Trypanosoma brucei I/6 autoantigen 0.0087 0.0324 0.0298
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.0966 0.1871
Onchocerca volvulus 0.0034 0.0033 0.0033
Trichomonas vaginalis calpain, putative 0.016 0.0731 0.1382
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1574 0.8527 0.8527
Onchocerca volvulus 0.0203 0.0966 0.0966
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0203 0.0966 0.1869
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Leishmania major cathepsin L-like protease 0.0914 0.4886 0.4873
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.0966 0.1871
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Trypanosoma cruzi calmodulin, putative 0.0087 0.0324 0.0298
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0534 0.279 0.2771
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Plasmodium falciparum serine repeat antigen 3 0.0203 0.0966 0.1869
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Giardia lamblia Cathepsin B precursor 0.0203 0.0966 0.2781
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0203 0.0966 0.0966
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0063 0.0191 0.0182
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0191 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0064
Entamoeba histolytica cysteine protease, putative 0.0203 0.0966 0.1871
Trypanosoma cruzi centrin-3 0.0087 0.0324 0.0298
Echinococcus multilocularis cathepsin L cysteine protease 0.0914 0.4886 0.4882
Trypanosoma cruzi C-8 sterol isomerase, putative 0.036 0.1828 0.1807
Echinococcus granulosus EF hand domain containing family member A2 0.0088 0.0333 0.0324
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0491 0.2556 0.2536
Brugia malayi cathepsin L-like cysteine proteinase 0.0203 0.0966 0.0966
Echinococcus multilocularis calcium uptake protein 1 0.0088 0.0333 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.045 0.2326 0.469
Onchocerca volvulus 0.0087 0.0324 0.0324
Schistosoma mansoni rab 0.0087 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0203 0.0966 0.0966
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0203 0.0966 0.2781
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0033
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0087 0.0324 0.0298
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0097 0.0097
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.016 0.0731 0.0706
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0203 0.0966 0.1869
Brugia malayi calpain 7 0.0534 0.279 0.279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0966 0.1871
Echinococcus multilocularis inhibitor of apoptosis protein 0.0175 0.0811 0.0803
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.016 0.0731 0.1382
Giardia lamblia Hypothetical protein 0.0088 0.0333 0.0824
Loa Loa (eye worm) hypothetical protein 0.1841 1 1
Trichomonas vaginalis calcium binding protein, putative 0.0087 0.0324 0.0538
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0064
Trypanosoma brucei calpain-like protein, putative 0.0534 0.279 0.2771
Echinococcus multilocularis calpain 5 0.0534 0.279 0.2784
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0491 0.2556 0.2536
Leishmania major cathepsin L-like protease 0.0914 0.4886 0.4873
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0064 0.0055
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0034 0.0033 0.0025
Onchocerca volvulus 0.0063 0.0191 0.0191
Echinococcus granulosus geminin 0.0168 0.077 0.0762
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Loa Loa (eye worm) calpain 0.0534 0.279 0.279
Brugia malayi calpain family protein 1 0.1415 0.7651 0.7651
Loa Loa (eye worm) histone deacetylase 0.0099 0.0393 0.0393
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.004 0.0066 0.0057
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0203 0.0966 0.1869
Trypanosoma cruzi cysteine peptidase, putative 0.1011 0.5423 0.5411
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0064 0.0064
Brugia malayi cathepsin F-like cysteine proteinase 0.0203 0.0966 0.0966
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0663 0.3499 0.3482
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0064 0.0064
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0033
Plasmodium vivax histone deacetylase 2, putative 0.0099 0.0393 0.068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0097 0.0097
Echinococcus granulosus caspase 2 0.0092 0.0354 0.0346
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0151 0.0086
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0083 0.0303 0.0303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0966 0.1871
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0333 0.0558
Onchocerca volvulus 0.0061 0.0184 0.0184
Brugia malayi Cytochrome P450 family protein 0.0033 0.0026 0.0026
Giardia lamblia Cathepsin L precursor 0.0203 0.0966 0.2781
Leishmania major histone deacetylase, putative 0.0099 0.0393 0.0368
Echinococcus multilocularis cathepsin b 0.1574 0.8527 0.8526
Plasmodium vivax vivapain-1 0.0491 0.2556 0.5165
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0333 0.0558
Trypanosoma cruzi calpain cysteine peptidase, putative 0.016 0.0731 0.0706
Plasmodium vivax serine-repeat antigen (SERA) 0.0203 0.0966 0.1869
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0203 0.0966 0.1869
Brugia malayi Peptidase C13 family protein 0.045 0.2326 0.2326
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.0203 0.0966 0.1871
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0534 0.279 0.2771
Toxoplasma gondii hypothetical protein 0.027 0.1332 0.1275
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Mycobacterium tuberculosis Long conserved protein 0.0284 0.1409 0.1348
Onchocerca volvulus 0.0482 0.2506 0.2506
Brugia malayi Pre-SET motif family protein 0.0061 0.0184 0.0184
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1841 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0064 0.0201 0.0283
Plasmodium vivax calpain, putative 0.0534 0.279 0.5651
Schistosoma mansoni hypothetical protein 0.0034 0.0033 0.0033
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0087 0.0324 0.0298
Onchocerca volvulus Histone deacetylase 10 homolog 0.0043 0.0081 0.0081
Schistosoma mansoni hemoglobinase (C13 family) 0.045 0.2326 0.2326
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Plasmodium falciparum serine repeat antigen 5 0.0203 0.0966 0.1869
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Leishmania major calmodulin-like protein 0.0087 0.0324 0.0298
Trypanosoma cruzi cysteine peptidase, putative 0.0914 0.4886 0.4873
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Onchocerca volvulus 0.0034 0.0033 0.0033
Trypanosoma brucei prolyl endopeptidase 0.1841 1 1
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0063 0.0191 0.0191
Trypanosoma cruzi cysteine protease, putative 0.0491 0.2556 0.2536
Giardia lamblia Cysteine protease 0.0203 0.0966 0.2781
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Giardia lamblia Encystation-specific protease 0.0203 0.0966 0.2781
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0064 0.0055
Echinococcus granulosus calumenin 0.0088 0.0333 0.0324
Mycobacterium ulcerans transglutaminase family protein 0.0284 0.1409 0.334
Toxoplasma gondii peptidase c13 family protein 0.0104 0.0421 0.0358
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.016 0.0731 0.0706
Leishmania major cathepsin L-like protease 0.0914 0.4886 0.4873
Trichomonas vaginalis centrin, putative 0.0087 0.0324 0.0538
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Schistosoma mansoni reticulocalbin 0.0088 0.0333 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0627 0.3305 0.672
Onchocerca volvulus Cathepsin L homolog 0.0914 0.4886 0.4886
Entamoeba histolytica cysteine protease, putative 0.0203 0.0966 0.1871
Schistosoma mansoni reticulocalbin 0.0087 0.0324 0.0324
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0064 0.0055
Loa Loa (eye worm) hypothetical protein 0.0155 0.0698 0.0698
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0191 0.0263
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.027 0.1332 0.263
Plasmodium vivax hypothetical protein, conserved 0.027 0.1332 0.2628
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0097 0.0089
Loa Loa (eye worm) hypothetical protein 0.016 0.0731 0.0731
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0063 0.0191 0.0165
Echinococcus multilocularis proteasome (prosome, macropain) 0.0083 0.0303 0.0294
Echinococcus granulosus histone deacetylase 6 0.0099 0.0393 0.0385
Loa Loa (eye worm) hypothetical protein 0.1574 0.8527 0.8527
Leishmania major centrin, putative 0.0087 0.0324 0.0298
Echinococcus granulosus EF hand domain containing family member A2 0.0087 0.0324 0.0315
Trypanosoma brucei proteasome subunit beta type-2, putative 0.004 0.0066 0.004
Loa Loa (eye worm) trypsin family protein 0.0034 0.0033 0.0033
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0083 0.0303 0.0495
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0025
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Trypanosoma cruzi cruzipain precursor, putative 0.0288 0.1435 0.1412
Brugia malayi prolyl oligopeptidase family protein 0.0663 0.3499 0.3499
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0203 0.0966 0.0966
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0064 0.0055
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0784 0.4168 0.4152
Echinococcus granulosus axis inhibition protein axin 0.004 0.0064 0.0055
Giardia lamblia Cathepsin B precursor 0.0203 0.0966 0.2781
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0191 0.0263
Trichomonas vaginalis calmodulin-2, putative 0.0087 0.0324 0.0538
Schistosoma mansoni calmodulin related calcium binding protein 0.0087 0.0324 0.0324
Brugia malayi hypothetical protein 0.0034 0.0033 0.0033
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Echinococcus multilocularis enteropeptidase 0.0034 0.0033 0.0025
Trichomonas vaginalis calpain, putative 0.016 0.0731 0.1382
Loa Loa (eye worm) hypothetical protein 0.036 0.1828 0.1828
Brugia malayi Papain family cysteine protease containing protein 0.0491 0.2556 0.2556
Trypanosoma brucei C-8 sterol isomerase, putative 0.036 0.1828 0.1807
Plasmodium vivax vivapain-3 0.0491 0.2556 0.5165
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0203 0.0966 0.1871
Mycobacterium leprae Conserved hypothetical protein 0.0284 0.1409 0.2863
Brugia malayi Cathepsin L-like precursor 0.0914 0.4886 0.4886
Onchocerca volvulus Cell death protein 3 homolog 0.0092 0.0354 0.0354
Trypanosoma cruzi oligopeptidase b 0.0784 0.4168 0.4152
Giardia lamblia Serine peptidase, putative 0.0063 0.0191 0.0387
Loa Loa (eye worm) calpain 5 0.0373 0.1905 0.1905
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.0539 0.0539
Brugia malayi Cathepsin L-like precursor 0.0626 0.3297 0.3297
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0393 0.0393
Echinococcus granulosus enteropeptidase 0.0034 0.0033 0.0025
Trypanosoma brucei histone deacetylase 2 0.0043 0.0081 0.0055
Echinococcus granulosus calpain A 0.1504 0.8138 0.8137
Loa Loa (eye worm) hypothetical protein 0.1042 0.5592 0.5592
Mycobacterium tuberculosis Conserved hypothetical protein 0.0284 0.1409 0.1348
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0064 0.0201 0.0175
Schistosoma mansoni neuronal calcium sensor 0.0087 0.0324 0.0324
Echinococcus multilocularis calpain 0.0534 0.279 0.2784
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Leishmania major histone deacetylase, putative 0.0088 0.0333 0.0308
Echinococcus multilocularis cathepsin L 0.0491 0.2556 0.2549
Loa Loa (eye worm) cathepsin B 0.0627 0.3305 0.3305
Trypanosoma cruzi kinesin, putative 0.0373 0.1905 0.1883
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0097 0.0089
Trypanosoma brucei calpain-like protein, putative 0.0534 0.279 0.2771
Mycobacterium ulcerans proteasome PrcB 0.0083 0.0303 0.0668
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.0966 0.0966
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0064 0.0055
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.1166 0.6276 0.6272
Brugia malayi fibroinase precursor 0.0203 0.0966 0.0966
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0087 0.0324 0.0298
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Loa Loa (eye worm) calmodulin-like protein 0.0087 0.0324 0.0324
Echinococcus multilocularis transmembrane protease serine 3 0.0034 0.0033 0.0025
Loa Loa (eye worm) calpain family protein 1 0.1042 0.5592 0.5592
Loa Loa (eye worm) fibroinase 0.0914 0.4886 0.4886
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0144 0.0144
Toxoplasma gondii histone deacetylase HDAC1 0.0099 0.0393 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0191 0.0263
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0063 0.0191 0.0263
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0203 0.0966 0.0966
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0203 0.0966 0.1869
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0966 0.1871
Onchocerca volvulus 0.0914 0.4886 0.4886
Toxoplasma gondii EF hand domain-containing protein 0.0087 0.0324 0.026
Schistosoma mansoni calpain-7 (C02 family) 0.0537 0.2806 0.2806
Trichomonas vaginalis peptide N-glycanase, putative 0.0284 0.1409 0.279
Giardia lamblia Cathepsin B precursor 0.0203 0.0966 0.2781
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0064 0.0064
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.016 0.0731 0.0706
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.045 0.2326 0.469
Giardia lamblia Transglutaminase/protease, putative 0.0284 0.1409 0.4148
Giardia lamblia Cysteine protease 0.0203 0.0966 0.2781
Loa Loa (eye worm) hypothetical protein 0.0203 0.0966 0.0966
Toxoplasma gondii calcium-dependent protein kinase 0.0088 0.0333 0.0269
Mycobacterium ulcerans hypothetical protein 0.0284 0.1409 0.334
Schistosoma mansoni cathepsin C 0.0203 0.0966 0.0966
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0203 0.0966 0.1869
Schistosoma mansoni cathepsin F (C01 family) 0.0914 0.4886 0.4886
Trypanosoma brucei protein I/6 0.0087 0.0324 0.0298
Echinococcus granulosus apoptotic protease activating factor 1 0.0092 0.0354 0.0346
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0064 0.0064
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.016 0.0731 0.0706
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0064 0.0055
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0175 0.0811 0.0811
Trypanosoma cruzi cysteine peptidase, putative 0.1011 0.5423 0.5411
Loa Loa (eye worm) hypothetical protein 0.1255 0.6766 0.6766
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Onchocerca volvulus 0.0034 0.0033 0.0033
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0663 0.3499 0.3482
Onchocerca volvulus 0.0284 0.1409 0.1409
Giardia lamblia Alanyl dipeptidyl peptidase 0.027 0.1332 0.3911
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0026 0.0026
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0175 0.0811 0.0803
Giardia lamblia Cathepsin L precursor 0.0203 0.0966 0.2781
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Echinococcus multilocularis calpain A 0.1504 0.8138 0.8137
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0534 0.279 0.2771
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1574 0.8527 0.8527
Loa Loa (eye worm) hypothetical protein 0.0626 0.3297 0.3297
Brugia malayi histone deacetylase 3 (HD3) 0.0088 0.0333 0.0333
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0064 0.0055
Entamoeba histolytica grainin 2 0.0087 0.0324 0.0538
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0063 0.0191 0.0263
Echinococcus granulosus histone deacetylase 6 0.0099 0.0393 0.0385
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0063 0.0191 0.0263
Echinococcus multilocularis programmed cell death protein 0.0087 0.0324 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Trichomonas vaginalis conserved hypothetical protein 0.0203 0.0966 0.1871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Giardia lamblia Cathepsin B precursor 0.0627 0.3305 1
Echinococcus multilocularis caspase 2 0.0092 0.0354 0.0346
Toxoplasma gondii centrin, putative 0.0087 0.0324 0.026
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0203 0.0966 0.1869
Plasmodium vivax unspecified product 0.0203 0.0966 0.1869
Loa Loa (eye worm) hypothetical protein 0.0061 0.0184 0.0184
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0184 0.0175
Schistosoma mansoni hypothetical protein 0.0168 0.077 0.077
Brugia malayi Serine protease Z688.6 precursor 0.0063 0.0191 0.0191
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0491 0.2556 0.2556
Loa Loa (eye worm) hypothetical protein 0.0063 0.0191 0.0191
Plasmodium vivax unspecified product 0.0491 0.2556 0.5165
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0064 0.0055
Giardia lamblia Cysteine protease 0.0203 0.0966 0.2781
Leishmania major cysteine peptidase A (CPA) 0.0914 0.4886 0.4873
Schistosoma mansoni cathepsin S (C01 family) 0.0203 0.0966 0.0966
Brugia malayi cathepsin Z-like cysteine proteinase 0.0203 0.0966 0.0966
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0087 0.0324 0.0535
Loa Loa (eye worm) hypothetical protein 0.0203 0.0966 0.0966
Onchocerca volvulus 0.0092 0.0354 0.0354
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis calcium binding protein, putative 0.0087 0.0324 0.0538
Schistosoma mansoni axis inhibition protein axin 0.004 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0087 0.0324 0.0324
Leishmania major centrin, putative,caltractin, putative 0.0087 0.0324 0.0298
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0034 0.0033 0.0025
Trichomonas vaginalis hypothetical protein 0.016 0.0731 0.1382
Toxoplasma gondii histone deacetylase HDAC3 0.0088 0.0333 0.0269
Brugia malayi Serine protease Z688.6 precursor 0.0063 0.0191 0.0191
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0784 0.4168 0.4152
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0087 0.0324 0.0298
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Echinococcus multilocularis centrin 2 0.0087 0.0324 0.0315
Loa Loa (eye worm) calpain D 0.016 0.0731 0.0731
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0288 0.1435 0.1435
Trichomonas vaginalis centrin, putative 0.0087 0.0324 0.0538
Trypanosoma brucei centrin, putative 0.0087 0.0324 0.0298
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1574 0.8527 0.8527
Trichomonas vaginalis calcineurin B subunit, putative 0.0087 0.0324 0.0538
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0175 0.0811 0.0811
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.3297 0.6704
Trypanosoma brucei oligopeptidase b 0.0784 0.4168 0.4152
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0064 0.0055
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.016 0.0731 0.0706
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0966 0.1871
Loa Loa (eye worm) hypothetical protein 0.0203 0.0966 0.0966
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0087 0.0324 0.0538
Schistosoma mansoni hypothetical protein 0.0034 0.0033 0.0033
Brugia malayi proteasome subunit beta type 2 0.004 0.0066 0.0066
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Mycobacterium leprae Conserved hypothetical protein 0.0284 0.1409 0.2863
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.027 0.1332 0.263
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Echinococcus granulosus histone deacetylase 0.0099 0.0393 0.0385
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1023 0.5488 0.5484
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0491 0.2556 0.2536
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0393 0.0385
Echinococcus multilocularis calpain family protein 1, d 0.1042 0.5592 0.5588
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.016 0.0731 0.0706
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0203 0.0966 0.2781
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0333 0.0558
Trichomonas vaginalis conserved hypothetical protein 0.016 0.0731 0.1382
Echinococcus multilocularis calumenin 0.0088 0.0333 0.0324
Loa Loa (eye worm) hypothetical protein 0.0914 0.4886 0.4886
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Echinococcus granulosus calpain 0.0534 0.279 0.2784
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1841 1 1
Echinococcus granulosus tumor protein p63 0.0346 0.1751 0.1744
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0064 0.0064
Giardia lamblia Thymus-specific serine protease precursor 0.0063 0.0191 0.0387
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1502 0.8129 0.8129
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0087 0.0324 0.0315
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.1166 0.6276 0.6276
Brugia malayi Cytochrome P450 family protein 0.0033 0.0026 0.0026
Entamoeba histolytica cysteine proteinase, putative 0.0491 0.2556 0.5167
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.0966 0.1871
Schistosoma mansoni cathepsin s 0.0288 0.1435 0.1435
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.016 0.0731 0.1382
Loa Loa (eye worm) hypothetical protein 0.0057 0.0158 0.0158
Brugia malayi hypothetical protein 0.0277 0.1374 0.1374
Trypanosoma cruzi kinesin, putative 0.0373 0.1905 0.1883
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0526 0.0518
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0333 0.0308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Leishmania major histone deacetylase, putative 0.0088 0.0333 0.0308
Loa Loa (eye worm) peptidase C13 family protein 0.045 0.2326 0.2326
Loa Loa (eye worm) hypothetical protein 0.0063 0.0192 0.0192
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0064 0.0201 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Brugia malayi Pre-SET motif family protein 0.0424 0.2183 0.2183
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Echinococcus granulosus glycoprotein Antigen 5 0.0034 0.0033 0.0025
Brugia malayi ERG2 and Sigma1 receptor like protein 0.036 0.1828 0.1828
Entamoeba histolytica histone deacetylase, putative 0.0088 0.0333 0.0558
Leishmania major hypothetical protein, conserved 0.0088 0.0333 0.0307
Echinococcus granulosus calpain A 0.0534 0.279 0.2784
Loa Loa (eye worm) hypothetical protein 0.0092 0.0354 0.0354
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0393 0.0368
Entamoeba histolytica cysteine proteinase, putative 0.0491 0.2556 0.5167
Echinococcus multilocularis acylamino acid releasing enzyme 0.027 0.1332 0.1325
Trypanosoma cruzi calmodulin, putative 0.0087 0.0324 0.0298
Schistosoma mansoni caspase-7 (C14 family) 0.0092 0.0354 0.0354
Brugia malayi programmed cell death protein 6 0.0087 0.0324 0.0324
Plasmodium vivax histone deacetylase, putative 0.0099 0.0393 0.068
Entamoeba histolytica calmodulin, putative 0.0087 0.0324 0.0538
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0534 0.279 0.2771
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0627 0.3305 0.3305
Plasmodium vivax vivapain-2 0.0914 0.4886 1
Entamoeba histolytica cysteine proteinase, putative 0.0491 0.2556 0.5167
Schistosoma mansoni histone deacetylase 0.0088 0.0333 0.0333
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.0539 0.0539
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0526 0.0518
Trypanosoma brucei calpain, putative 0.016 0.0731 0.0706
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0333 0.0558
Trypanosoma brucei histone deacetylase 3 0.0099 0.0393 0.0368
Brugia malayi PXA domain containing protein 0.004 0.0064 0.0064
Echinococcus multilocularis calmodulin 0.0087 0.0324 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Entamoeba histolytica hypothetical protein, conserved 0.027 0.1332 0.263
Loa Loa (eye worm) hypothetical protein 0.0288 0.1435 0.1435
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0303 0.0277
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Schistosoma mansoni calpain (C02 family) 0.0534 0.279 0.279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0203 0.0966 0.1871
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0201 0.0175
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Brugia malayi hypothetical protein 0.0092 0.0354 0.0354
Mycobacterium tuberculosis Conserved hypothetical protein 0.0284 0.1409 0.1348
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0104 0.0421 0.0396
Trypanosoma brucei Calpain-like protein 1.2 0.016 0.0731 0.0706
Echinococcus multilocularis calpain 7 (C02 family) 0.0534 0.279 0.2784
Entamoeba histolytica calcium-binding protein, putative 0.0087 0.0324 0.0538
Trypanosoma cruzi calmodulin, putative 0.0087 0.0324 0.0298
Echinococcus granulosus Mastin 0.0034 0.0033 0.0025
Brugia malayi hypothetical protein 0.0155 0.0698 0.0698
Echinococcus granulosus cathepsin l1 0.0914 0.4886 0.4882
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0064 0.0055
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0081 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0526 0.1208
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0663 0.3499 0.3494
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0063 0.0191 0.0191
Onchocerca volvulus 0.0914 0.4886 0.4886
Plasmodium falciparum serine repeat antigen 2 0.0203 0.0966 0.1869
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Entamoeba histolytica hypothetical protein 0.0203 0.0966 0.1871
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Schistosoma mansoni regulator of G protein signaling 0.004 0.0064 0.0064
Plasmodium falciparum centrin-1 0.0087 0.0324 0.0535
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0914 0.4886 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Loa Loa (eye worm) hypothetical protein 0.0288 0.1435 0.1435
Brugia malayi Cathepsin L-like precursor 0.0914 0.4886 0.4886
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0393 0.0385
Entamoeba histolytica dipeptidyl-peptidase, putative 0.027 0.1332 0.263
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0526 0.1208
Echinococcus granulosus inhibitor of apoptosis protein 0.0175 0.0811 0.0803
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0066 0.0003
Echinococcus granulosus neuronal calcium sensor 0.0087 0.0324 0.0315
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0333 0.0558
Leishmania major cathepsin L-like protease 0.1011 0.5423 0.5411
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0064 0.0055
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0026 0.0026
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0203 0.0966 0.0966
Entamoeba histolytica cysteine protease, putative 0.0914 0.4886 1
Schistosoma mansoni microtubule-associated protein tau 0.1427 0.7718 0.7718
Brugia malayi histone deacetylase 11 0.0043 0.0081 0.0081
Trypanosoma cruzi I/6 autoantigen, putative 0.0087 0.0324 0.0298
Leishmania major histone deacetylase, putative 0.0099 0.0393 0.0368
Loa Loa (eye worm) hypothetical protein 0.0051 0.0124 0.0124
Echinococcus multilocularis cathepsin L cysteine protease 0.0914 0.4886 0.4882
Entamoeba histolytica dipeptidyl-peptidase, putative 0.027 0.1332 0.263
Trypanosoma cruzi conserved protein 0.016 0.0731 0.0706
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0914 0.4886 0.4886
Plasmodium falciparum peptidase, putative 0.027 0.1332 0.2628
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0064 0.0201 0.028
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0627 0.3305 0.3287
Toxoplasma gondii prolyl endopeptidase 0.1841 1 1
Giardia lamblia Cathepsin L-like protease 0.0203 0.0966 0.2781
Trypanosoma brucei histone deacetylase 1 0.0088 0.0333 0.0308
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0064 0.0064
Entamoeba histolytica cysteine protease, putative 0.0203 0.0966 0.1871
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0393 0.0393
Schistosoma mansoni inhibitor of apoptosis protein 0.0175 0.0811 0.0811
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0324 0.0538
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0203 0.0966 0.1871
Schistosoma mansoni regulator of G protein signaling 0.004 0.0064 0.0064
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0203 0.0966 0.1869
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.016 0.0731 0.0706
Schistosoma mansoni hypothetical protein 0.0092 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0626 0.3297 0.3297
Plasmodium falciparum cysteine proteinase falcipain 1 0.0491 0.2556 0.5165
Brugia malayi Cathepsin L-like cysteine proteinase 0.0626 0.3297 0.3297
Echinococcus multilocularis histone deacetylase 7 0.0099 0.0393 0.0385
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0087 0.0324 0.0538
Schistosoma mansoni neuronal calcium sensor 0.0087 0.0324 0.0324
Entamoeba histolytica grainin, putative 0.0088 0.0333 0.0557
Schistosoma mansoni calpain-7 (C02 family) 0.0537 0.2806 0.2806
Echinococcus granulosus cathepsin L cysteine proteinase 0.0914 0.4886 0.4882
Loa Loa (eye worm) programmed cell death protein 6 0.0088 0.0333 0.0333
Onchocerca volvulus Cathepsin L homolog 0.0914 0.4886 0.4886
Echinococcus granulosus cathepsin b 0.1574 0.8527 0.8526
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0333 0.0554
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0097 0.0089
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Onchocerca volvulus 0.0088 0.0333 0.0333
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0333 0.0308
Trypanosoma brucei cysteine peptidase C (CPC) 0.0627 0.3305 0.3287
Plasmodium falciparum calpain 0.016 0.0731 0.1379
Entamoeba histolytica prolyl oligopeptidase family protein 0.027 0.1332 0.263
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.0966 0.1871
Entamoeba histolytica cysteine proteinase, putative 0.0626 0.3297 0.6704
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0526 0.0526
Schistosoma mansoni cpg binding protein 0.003 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.3297 0.6704
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Loa Loa (eye worm) proteasome subunit beta type 2 0.004 0.0066 0.0066
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0168 0.0159
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.045 0.2326 0.469
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Echinococcus granulosus Transglutaminase 0.0284 0.1409 0.1402
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1023 0.5488 0.5484
Schistosoma mansoni hypothetical protein 0.0399 0.2047 0.2047
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0066 0.0003
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.004 0.0066 0.004
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0203 0.0966 0.1869
Loa Loa (eye worm) hypothetical protein 0.0088 0.0333 0.0333
Schistosoma mansoni calmodulin 0.0087 0.0324 0.0324
Leishmania major hypothetical protein, conserved 0.016 0.0731 0.0706
Brugia malayi Trypsin-like protease protein 5 0.0034 0.0033 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0184 0.0184
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0081 0.0081
Brugia malayi calpain 5 0.016 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0203 0.0966 0.1871
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0066 0.0066
Toxoplasma gondii troponin c, isotype gamma, putative 0.0087 0.0324 0.026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0184 0.0184
Onchocerca volvulus 0.0034 0.0033 0.0033
Schistosoma mansoni cathepsin F (C01 family) 0.0914 0.4886 0.4886
Plasmodium falciparum histone deacetylase, putative 0.0099 0.0393 0.068
Onchocerca volvulus 0.0034 0.0033 0.0033
Onchocerca volvulus Cathepsin L homolog 0.0203 0.0966 0.0966
Loa Loa (eye worm) ctsf protein 0.0914 0.4886 0.4886
Trypanosoma brucei centrin, putative 0.0087 0.0324 0.0298
Brugia malayi cathepsin Z-like cysteine proteinase 0.0203 0.0966 0.0966
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.1166 0.6276 0.6272
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0663 0.3499 0.3499
Schistosoma mansoni hypothetical protein 0.0087 0.0324 0.0324
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0066 0.0066
Plasmodium falciparum serine repeat antigen 6 0.0203 0.0966 0.1869
Brugia malayi cathepsin L precursor 0.0203 0.0966 0.0966
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Schistosoma mansoni centrin 0.0087 0.0324 0.0324
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0627 0.3305 0.3287
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Echinococcus granulosus histone deacetylase 1 0.0088 0.0333 0.0325
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0064 0.0064
Onchocerca volvulus 0.0051 0.0124 0.0124
Echinococcus granulosus EF HAND 1 calcium binding site 0.0087 0.0324 0.0315
Brugia malayi cathepsin L-like precursor 0.0626 0.3297 0.3297
Onchocerca volvulus 0.0914 0.4886 0.4886
Echinococcus granulosus proteasome prosome macropain 0.0083 0.0303 0.0294
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0203 0.0966 0.1871
Echinococcus granulosus cathepsin l cysteine peptidase 0.0914 0.4886 0.4882
Trypanosoma cruzi cysteine peptidase, putative 0.0288 0.1435 0.1412
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0088 0.0333 0.0333
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0104 0.0421 0.074
Trichomonas vaginalis calcium binding protein, putative 0.0087 0.0324 0.0538
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Leishmania major calmodulin, putative 0.0087 0.0324 0.0298
Brugia malayi Cathepsin L-like precursor 0.0914 0.4886 0.4886
Brugia malayi Proteasome A-type and B-type family protein 0.0083 0.0303 0.0303
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0201 0.0175
Onchocerca volvulus 0.0034 0.0033 0.0033
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.0966 0.0966
Toxoplasma gondii hypothetical protein 0.016 0.0731 0.0669
Echinococcus multilocularis programmed cell death protein 0.0087 0.0324 0.0315
Trypanosoma cruzi hypothetical protein, conserved 0.027 0.1332 0.131
Loa Loa (eye worm) calpain family protein 1 0.1415 0.7651 0.7651
Brugia malayi hypothetical protein 0.004 0.0064 0.0064
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0124 0.0124
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0784 0.4168 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Giardia lamblia Histone deacetylase 0.0088 0.0333 0.0826
Loa Loa (eye worm) hypothetical protein 0.0203 0.0966 0.0966
Trypanosoma brucei hypothetical protein 0.016 0.0731 0.0706
Loa Loa (eye worm) cysteine protease 0.0914 0.4886 0.4886
Onchocerca volvulus Prolyl endopeptidase homolog 0.1841 1 1
Brugia malayi proteasome subunit beta type 1 0.0064 0.0201 0.0201
Entamoeba histolytica cysteine protease, putative 0.0203 0.0966 0.1871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1502 0.8129 0.8128
Giardia lamblia GPI-anchor transamidase, putative 0.0104 0.0421 0.1097
Onchocerca volvulus 0.0914 0.4886 0.4886
Brugia malayi GPI-anchor transamidase 0.0104 0.0421 0.0421
Brugia malayi EF hand family protein 0.0088 0.0333 0.0333
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0333 0.0558
Onchocerca volvulus 0.0881 0.4707 0.4707
Leishmania major protein kinase, putative 0.0087 0.0324 0.0298
Toxoplasma gondii preprocathepsin c precursor, putative 0.0203 0.0966 0.0907
Entamoeba histolytica GPI-anchor transamidase, putative 0.0104 0.0421 0.074
Echinococcus multilocularis GPI anchor transamidase 0.0104 0.0421 0.0413
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0663 0.3499 0.3482
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.016 0.0731 0.1382
Schistosoma mansoni cpg binding protein 0.003 0.0009 0.0009
Brugia malayi Histone deacetylase 1 0.0088 0.0333 0.0333
Trichomonas vaginalis calcineurin B subunit, putative 0.0088 0.0333 0.0557
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0064 0.0055
Echinococcus granulosus histone deacetylase 8 0.0043 0.0081 0.0072
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1415 0.7651 0.7651
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Brugia malayi PXA domain containing protein 0.004 0.0064 0.0064
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0526 0.0526
Onchocerca volvulus 0.0914 0.4886 0.4886
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Loa Loa (eye worm) hypothetical protein 0.0184 0.0859 0.0859
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0063 0.0191 0.0165
Brugia malayi cathepsin B-like cysteine proteinase 0.1574 0.8527 0.8527
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0534 0.279 0.2771
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0097 0.0097
Echinococcus multilocularis histone deacetylase 0.0099 0.0393 0.0385
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0088 0.0333 0.0307
Entamoeba histolytica cysteine protease, putative 0.0203 0.0966 0.1871
Trypanosoma brucei hypothetical protein, conserved 0.0087 0.0324 0.0298
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0064 0.0064
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0026 0.0026
Schistosoma mansoni calmodulin 0.0087 0.0324 0.0324
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0184 0.0175
Trichomonas vaginalis myosin light chain 1, putative 0.0087 0.0324 0.0538
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0064 0.0064
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.1163 0.1155
Echinococcus multilocularis cathepsin L 0.0203 0.0966 0.0958
Echinococcus granulosus calmodulin 0.0087 0.0324 0.0315
Giardia lamblia Cathepsin L precursor 0.0203 0.0966 0.2781
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0526 0.0272
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0175 0.0811 0.0803
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1574 0.8527 0.8523
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.027 0.1332 0.1275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Loa Loa (eye worm) hypothetical protein 0.0277 0.1374 0.1374
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0184 0.0119
Loa Loa (eye worm) hypothetical protein 0.1415 0.7651 0.7651
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0333 0.0558
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0723 0.3834 0.3818
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0064
Echinococcus multilocularis prolyl endopeptidase 0.1841 1 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0034 0.0033 0.0033
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0203 0.0966 0.1869
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0083 0.0303 0.0732
Echinococcus granulosus microtubule associated protein 2 0.1427 0.7718 0.7716
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0175 0.0811 0.0811
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0064 0.0055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.027 0.1332 0.1332
Trypanosoma brucei calpain-like protein, putative 0.0534 0.279 0.2771
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0914 0.4886 0.4882
Trypanosoma brucei antigen, putative 0.0534 0.279 0.2771
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Toxoplasma gondii cathepsin B 0.0627 0.3305 0.3261
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0082 0.0016
Brugia malayi histone deacetylase 1 (HD1) 0.0088 0.0333 0.0333
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Echinococcus granulosus GPI anchor transamidase 0.0104 0.0421 0.0413
Schistosoma mansoni histone deacetylase 1 2 3 0.0043 0.0081 0.0081
Trypanosoma brucei calmodulin, putative 0.0088 0.0333 0.0307
Brugia malayi Histone deacetylase family protein 0.0099 0.0393 0.0393
Brugia malayi Cell death protein 3 precursor 0.0092 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0064
Leishmania major calpain family cysteine protease-like protein 0.016 0.0731 0.0706
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0203 0.0966 0.1869
Plasmodium vivax histone deacetylase 1, putative 0.0088 0.0333 0.0555
Echinococcus multilocularis tumor protein p63 0.0346 0.1751 0.1744
Echinococcus multilocularis neurocalcin 0.0087 0.0324 0.0315
Loa Loa (eye worm) hypothetical protein 0.0626 0.3297 0.3297
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Schistosoma mansoni regulator of G protein signaling 0.004 0.0064 0.0064
Echinococcus granulosus cathepsin l1 0.0626 0.3297 0.3291
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.045 0.2326 0.469
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0534 0.279 0.2771
Leishmania major calmodulin, putative 0.0087 0.0324 0.0298
Echinococcus granulosus cysteine protease 0.0491 0.2556 0.2549
Brugia malayi Trypsin family protein 0.0034 0.0033 0.0033
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0087 0.0324 0.0324
Trypanosoma brucei proteasome beta 6 subunit 0.0064 0.0201 0.0175
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0104 0.0421 0.074
Giardia lamblia Proteasome subunit beta type 1 0.0064 0.0201 0.0417
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.1163 0.1155
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.016 0.0731 0.1382
Trypanosoma brucei cysteine peptidase, putative 0.016 0.0731 0.0706
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0083 0.0303 0.0277
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1023 0.5488 0.5488
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0104 0.0421 0.0396
Trypanosoma brucei calmodulin, putative 0.0087 0.0324 0.0298
Trichomonas vaginalis set domain proteins, putative 0.0482 0.2505 0.5062
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0547 0.286 0.2813
Trypanosoma cruzi centrin, putative 0.0087 0.0324 0.0298
Brugia malayi Serine carboxypeptidase S28 family protein 0.0063 0.0191 0.0191
Trypanosoma cruzi cysteine proteinase, putative 0.0491 0.2556 0.2536
Giardia lamblia Cathepsin L precursor 0.0203 0.0966 0.2781
Leishmania major cathepsin L-like protease 0.0914 0.4886 0.4873
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0914 0.4886 0.4882
Giardia lamblia Cathepsin B precursor 0.0627 0.3305 1
Loa Loa (eye worm) histone deacetylase 11 0.0043 0.0081 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Mycobacterium ulcerans hypothetical protein 0.0034 0.0033 0.0018
Entamoeba histolytica protein kinase, putative 0.0373 0.1905 0.3817
Plasmodium falciparum GPI-anchor transamidase, putative 0.0104 0.0421 0.0737
Giardia lamblia Cysteine protease 0.0203 0.0966 0.2781
Entamoeba histolytica cysteine proteinase, putative 0.0914 0.4886 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0914 0.4886 1
Trypanosoma brucei mitochondrial calcium uptake 1 0.0087 0.0324 0.0298
Brugia malayi Cytochrome P450 family protein 0.0054 0.0144 0.0144
Trypanosoma brucei calpain, putative 0.016 0.0731 0.0706
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0663 0.3499 0.3482
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0203 0.0966 0.1869
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0203 0.0966 0.0966
Brugia malayi Papain family cysteine protease containing protein 0.0914 0.4886 0.4886
Loa Loa (eye worm) hypothetical protein 0.0239 0.1163 0.1163
Echinococcus multilocularis EF hand domain containing family member A2 0.0087 0.0324 0.0315
Plasmodium vivax proteasome subunit beta type-1, putative 0.0064 0.0201 0.028
Schistosoma mansoni mitochondrial solute carrier 0.0087 0.0324 0.0324
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0333 0.0558
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0063 0.0191 0.0165
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.016 0.0731 0.0706
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.027 0.1332 0.131
Echinococcus granulosus acylamino acid releasing enzyme 0.027 0.1332 0.1325
Loa Loa (eye worm) hypothetical protein 0.0063 0.0191 0.0191
Echinococcus granulosus histone deacetylase 7 0.0099 0.0393 0.0385
Schistosoma mansoni memapsin-2 (A01 family) 0.0431 0.222 0.222
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.045 0.2326 0.469
Trypanosoma cruzi cysteine proteinase, putative 0.0491 0.2556 0.2536
Schistosoma mansoni neuronal calcium sensor 0.0087 0.0324 0.0324
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0104 0.0421 0.074
Giardia lamblia Cathepsin L precursor 0.0203 0.0966 0.2781
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1502 0.8129 0.8129
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0064 0.0055
Trichomonas vaginalis calcium binding proteins, putative 0.0087 0.0324 0.0538
Trypanosoma cruzi centrin, putative 0.0087 0.0324 0.0298
Loa Loa (eye worm) prolyl oligopeptidase 0.1023 0.5488 0.5488
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0087 0.0324 0.0298
Trypanosoma cruzi major cysteine proteinase, putative 0.0301 0.1503 0.1481
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0324 0.0538
Echinococcus granulosus calpain 7 C02 family 0.0534 0.279 0.2784
Entamoeba histolytica calcium binding family protein 0.0087 0.0324 0.0538
Entamoeba histolytica cysteine proteinase, putative 0.0491 0.2556 0.5167
Trypanosoma cruzi prolyl endopeptidase 0.1841 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.0966 0.0966
Trypanosoma cruzi cruzipain precursor, putative 0.1011 0.5423 0.5411
Schistosoma mansoni survival motor neuron protein 0.0049 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0087 0.0324 0.0324
Plasmodium falciparum serine repeat antigen 1 0.0203 0.0966 0.1869
Trypanosoma cruzi I/6 autoantigen, putative 0.0087 0.0324 0.0298
Schistosoma mansoni cathepsin B (C01 family) 0.0203 0.0966 0.0966
Echinococcus multilocularis neuronal calcium sensor 0.0087 0.0324 0.0315
Onchocerca volvulus Cathepsin F homolog 0.0914 0.4886 0.4886
Giardia lamblia Hypothetical protein 0.0203 0.0966 0.2781
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0064 0.0055
Loa Loa (eye worm) hypothetical protein 0.0043 0.0081 0.0081
Echinococcus multilocularis calmodulin 0.0087 0.0324 0.0315
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0104 0.0421 0.0421
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Brugia malayi Trypsin family protein 0.0034 0.0033 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.016 0.0731 0.0706
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0064 0.0201 0.0192
Echinococcus granulosus expressed protein 0.0772 0.4104 0.4099
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0064 0.0201 0.0283
Schistosoma mansoni hypothetical protein 0.016 0.0731 0.0731
Echinococcus multilocularis cysteine protease 0.0914 0.4886 0.4882
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0784 0.4168 1
Echinococcus multilocularis Mastin 0.0034 0.0033 0.0025
Loa Loa (eye worm) hypothetical protein 0.0288 0.1435 0.1435
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0114 0.0114
Leishmania major phospholipase c-like protein 0.0087 0.0324 0.0298
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0784 0.4168 0.4707
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trypanosoma brucei Component of motile flagella 41 0.0087 0.0324 0.0298
Brugia malayi Cathepsin L-like precursor 0.0914 0.4886 0.4886
Toxoplasma gondii histone deacetylase HDAC4 0.0043 0.0081 0.0015
Loa Loa (eye worm) proteasome subunit beta type 1 0.0064 0.0201 0.0201
Leishmania major calmodulin-like protein 0.0087 0.0324 0.0298
Schistosoma mansoni histone deacetylase hda2 0.0106 0.0428 0.0428
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0097 0.0089
Onchocerca volvulus 0.0175 0.0811 0.0811
Echinococcus multilocularis hypothetical protein 0.0534 0.279 0.2784
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0064 0.0064
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0203 0.0966 0.1869
Brugia malayi cathepsin F-like cysteine proteinase 0.0288 0.1435 0.1435
Giardia lamblia Hypothetical protein 0.0284 0.1409 0.4148
Loa Loa (eye worm) prolyl oligopeptidase 0.027 0.1332 0.1332
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Plasmodium falciparum histone deacetylase 2 0.0099 0.0393 0.068
Loa Loa (eye worm) hypothetical protein 0.0063 0.0191 0.0191
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1841 1 1
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0393 0.0368
Onchocerca volvulus 0.0626 0.3297 0.3297
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0064 0.0055
Toxoplasma gondii proteasome subunit beta type, putative 0.0083 0.0303 0.0239
Entamoeba histolytica calmodulin, putative 0.0087 0.0324 0.0538
Trypanosoma brucei histone deacetylase 4 0.0099 0.0393 0.0368
Echinococcus granulosus calcium uptake protein 1 0.0088 0.0333 0.0324
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0303 0.0277
Toxoplasma gondii histone deacetylase HDAC2 0.0088 0.0333 0.0269
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1011 0.5423 0.5411
Echinococcus multilocularis Transglutaminase 0.0284 0.1409 0.1402
Leishmania major centrin, putative 0.0087 0.0324 0.0298
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0087 0.0324 0.0538
Trypanosoma cruzi major cysteine proteinase, putative 0.0203 0.0966 0.0943
Brugia malayi Cathepsin L-like precursor 0.0288 0.1435 0.1435
Onchocerca volvulus 0.0914 0.4886 0.4886
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0534 0.279 0.2771
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0064 0.0064
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0066 0.004
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0087 0.0324 0.0315
Onchocerca volvulus Deterin homolog 0.0175 0.0811 0.0811
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0184 0.0184
Mycobacterium tuberculosis Conserved protein 0.0284 0.1409 0.1348
Loa Loa (eye worm) hypothetical protein 0.0385 0.1971 0.1971
Plasmodium falciparum serine repeat antigen 9 0.0203 0.0966 0.1869
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Trypanosoma brucei calpain-like protein, putative 0.0534 0.279 0.2771
Toxoplasma gondii EFHC1, putative 0.0087 0.0324 0.026
Plasmodium vivax histone deacetylase, putative 0.0043 0.0081 0.0031
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0203 0.0966 0.1871
Leishmania major calpain protease-like protein 0.016 0.0731 0.0706
Plasmodium vivax unspecified product 0.0288 0.1435 0.284
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.004 0.0066 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.016 0.0731 0.1382
Toxoplasma gondii cathepsin CPC2 0.0203 0.0966 0.0907
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0203 0.0966 0.1871
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0083 0.0303 0.0303
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0663 0.3499 0.3482
Echinococcus granulosus programmed cell death protein 0.0087 0.0324 0.0315
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0526 0.0501
Trypanosoma brucei Calpain-like protein 2 0.016 0.0731 0.0706
Onchocerca volvulus 0.0914 0.4886 0.4886
Giardia lamblia Cathepsin B precursor 0.0627 0.3305 1
Toxoplasma gondii cathepsin CPC1 0.0203 0.0966 0.0907
Echinococcus granulosus cathepsin L cysteine protease 0.0491 0.2556 0.2549
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0203 0.0966 0.0966
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0784 0.4168 0.4152
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0288 0.1435 0.1435
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.027 0.1332 0.1332
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.045 0.2326 0.2326
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0033
Plasmodium falciparum serine repeat antigen 7 0.0203 0.0966 0.1869
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0064 0.0064
Echinococcus multilocularis EF hand domain containing family member A2 0.0088 0.0333 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0191 0.0263
Mycobacterium ulcerans putative transglutaminase-like protein 0.0284 0.1409 0.334
Giardia lamblia Alanyl dipeptidyl peptidase 0.027 0.1332 0.3911
Echinococcus multilocularis apoptotic protease activating factor 1 0.0092 0.0354 0.0346
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0034 0.0033 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0534 0.279 0.2771
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0064 0.0055
Trypanosoma brucei histone deacetylase, putative 0.0099 0.0393 0.0368
Onchocerca volvulus 0.0049 0.0114 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.1011 0.5423 0.5411
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0914 0.4886 1
Leishmania major oligopeptidase b 0.0784 0.4168 0.4152
Echinococcus multilocularis histone deacetylase 1 0.0088 0.0333 0.0325
Trichomonas vaginalis calpain, putative 0.016 0.0731 0.1382
Brugia malayi calcium-binding protein 0.0087 0.0324 0.0324
Echinococcus multilocularis expressed protein 0.0772 0.4104 0.4099
Brugia malayi Cathepsin L-like precursor 0.0914 0.4886 0.4886
Echinococcus multilocularis cathepsin b 0.1574 0.8527 0.8526
Trypanosoma cruzi caltractin, putative 0.0087 0.0324 0.0298
Leishmania major programmed cell death 6 protein-like protein 0.0087 0.0324 0.0298
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0914 0.4886 0.4886
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0175 0.0811 0.0811
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.016 0.0731 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.027 0.1332 0.263
Plasmodium vivax GPI-anchor transamidase, putative 0.0104 0.0421 0.0737
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.0966 0.0966
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0203 0.0966 0.2781
Trichomonas vaginalis calmodulin, putative 0.0088 0.0333 0.0557
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.045 0.2326 0.469
Schistosoma mansoni hypothetical protein 0.0087 0.0324 0.0324
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0064 0.0201 0.0201
Entamoeba histolytica hypothetical protein, conserved 0.0088 0.0333 0.0557
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0491 0.2556 0.5167
Schistosoma mansoni hemoglobinase (C13 family) 0.045 0.2326 0.2326
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.016 0.0731 0.0706
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0104 0.0421 0.0396
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0203 0.0966 0.2781
Brugia malayi Calmodulin-like protein 0.0087 0.0324 0.0324
Schistosoma mansoni histone deacetylase 0.0088 0.0333 0.0333
Plasmodium vivax vivapain-2 0.0914 0.4886 1
Brugia malayi calpain 5 0.0373 0.1905 0.1905
Loa Loa (eye worm) hypothetical protein 0.0881 0.4707 0.4707
Brugia malayi EF hand family protein 0.0087 0.0324 0.0324
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Leishmania major cathepsin L-like protease 0.1011 0.5423 0.5411
Trypanosoma cruzi cysteine peptidase, putative 0.0491 0.2556 0.2536
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Echinococcus multilocularis geminin 0.0168 0.077 0.0762
Entamoeba histolytica calpain large subunit domain III containing protein 0.0373 0.1905 0.3817
Echinococcus granulosus histone deacetylase 6 0.0106 0.0428 0.0419
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1572 0.8513 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.0966 0.0966
Plasmodium vivax proteasome subunit beta type-5, putative 0.0083 0.0303 0.0492
Leishmania major kinesin, putative 0.0373 0.1905 0.1883
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0203 0.0966 0.0966
Trichomonas vaginalis calcium binding protein, putative 0.0087 0.0324 0.0538
Brugia malayi hypothetical protein 0.0239 0.1163 0.1163
Echinococcus granulosus prolyl endopeptidase 0.1841 1 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0033
Loa Loa (eye worm) histone deacetylase 1 0.0088 0.0333 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0033 0.0033
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0175 0.0811 0.0811
Brugia malayi prolyl oligopeptidase family protein 0.1023 0.5488 0.5488
Trichomonas vaginalis calmodulin, putative 0.0087 0.0324 0.0538
Brugia malayi Papain family cysteine protease containing protein 0.0491 0.2556 0.2556
Schistosoma mansoni ef hand domain family member A2 0.0087 0.0324 0.0324
Loa Loa (eye worm) histone deacetylase 7A 0.0099 0.0393 0.0393
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.2183 0.2183
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.2047 0.204
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0063 0.0191 0.0182
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Entamoeba histolytica cysteine protease, putative 0.0491 0.2556 0.5167
Onchocerca volvulus 0.0155 0.0698 0.0698
Trypanosoma brucei caltractin, putative 0.0087 0.0324 0.0298
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.016 0.0731 0.0669
Brugia malayi calpain D 0.016 0.0731 0.0731
Brugia malayi Histone deacetylase family protein 0.0099 0.0393 0.0393
Leishmania major proteasome beta 5 subunit, putative 0.0083 0.0303 0.0277
Echinococcus granulosus centrin 2 0.0087 0.0324 0.0315
Plasmodium vivax serine-repeat antigen (SERA) 0.0203 0.0966 0.1869
Brugia malayi Cathepsin L-like precursor 0.0626 0.3297 0.3297
Giardia lamblia Hypothetical protein 0.0203 0.0966 0.2781
Plasmodium falciparum serine repeat antigen 8 0.0203 0.0966 0.1869
Trypanosoma brucei Calpain-like protein 1.1 0.016 0.0731 0.0706
Plasmodium falciparum proteasome subunit beta type-5 0.0083 0.0303 0.0492
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0914 0.4886 1
Schistosoma mansoni axis inhibition protein axin 0.004 0.0064 0.0064
Entamoeba histolytica cysteine proteinase 1, putative 0.0491 0.2556 0.5167
Brugia malayi prolyl oligopeptidase family protein 0.027 0.1332 0.1332
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0087 0.0324 0.0298
Echinococcus granulosus cathepsin L 0.0203 0.0966 0.0958
Echinococcus multilocularis histone deacetylase 3 0.0088 0.0333 0.0325
Plasmodium vivax centrin-1, putative 0.0087 0.0324 0.0535
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0081 0.0055
Trypanosoma brucei Calpain-like protein CALP1.3 0.016 0.0731 0.0706
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0191 0.0263
Brugia malayi Cathepsin L-like precursor 0.0914 0.4886 0.4886
Toxoplasma gondii calmodulin CAM1 0.0088 0.0333 0.0269
Brugia malayi Thioredoxin family protein 0.0284 0.1409 0.1409
Brugia malayi hypothetical protein 0.004 0.0064 0.0064
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1574 0.8527 0.8527
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0203 0.0966 0.1871
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.016 0.0731 0.0706
Leishmania major hypothetical protein, unknown function 0.016 0.0731 0.0706
Trypanosoma brucei prolyl oligopeptidase, putative 0.0784 0.4168 0.4152
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Schistosoma mansoni calpain C (C02 family) 0.0534 0.279 0.279
Brugia malayi Trypsin family protein 0.0034 0.0033 0.0033
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0087 0.0324 0.0315
Brugia malayi calpain family protein 1 0.1415 0.7651 0.7651
Loa Loa (eye worm) RGS-3 protein 0.004 0.0064 0.0064
Entamoeba histolytica calpain family cysteine protease, putative 0.016 0.0731 0.1382
Brugia malayi Trypsin family protein 0.0034 0.0033 0.0033
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0526 0.0464
Leishmania major hypothetical protein, conserved 0.0087 0.0324 0.0298
Echinococcus multilocularis histone deacetylase 8 0.0043 0.0081 0.0072
Loa Loa (eye worm) histone deacetylase 3 0.0088 0.0333 0.0333

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 70.7946 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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