Detailed information for compound 1529338

Basic information

Technical information
  • TDR Targets ID: 1529338
  • Name: diethyl 1-[2-oxo-2-(phenylamino)ethyl]triazol e-4,5-dicarboxylate
  • MW: 346.338 | Formula: C16H18N4O5
  • H donors: 1 H acceptors: 5 LogP: 1.8 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1n(nnc1C(=O)OCC)CC(=O)Nc1ccccc1
  • InChi: 1S/C16H18N4O5/c1-3-24-15(22)13-14(16(23)25-4-2)20(19-18-13)10-12(21)17-11-8-6-5-7-9-11/h5-9H,3-4,10H2,1-2H3,(H,17,21)
  • InChiKey: WOJQYVDJMNZBSC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-[2-oxo-2-(phenylamino)ethyl]triazole-4,5-dicarboxylic acid diethyl ester
  • 1-[2-keto-2-(phenylamino)ethyl]triazole-4,5-dicarboxylic acid diethyl ester
  • diethyl 1-[2-oxo-2-(phenylamino)ethyl]-1,2,3-triazole-4,5-dicarboxylate
  • STK305779
  • SMR000309076
  • diethyl 1-(2-anilino-2-oxoethyl)-1H-1,2,3-triazole-4,5-dicarboxylate
  • MLS000730701

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.036 0.1058 0.1944
Leishmania major histone deacetylase, putative 0.0102 0.0249 0.0442
Echinococcus granulosus endothelin converting enzyme 1 0.0095 0.0226 0.0226
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0044 0.0066 0.0066
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0228 0.0228
Schistosoma mansoni hypothetical protein 0.0141 0.037 0.037
Entamoeba histolytica calpain family cysteine protease, putative 0.0286 0.0826 0.2198
Onchocerca volvulus Cathepsin F homolog 0.1209 0.3719 0.6889
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0042 0.006 0.006
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0786 0.2392 0.2392
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0062 0.0138
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0297 0.0859 0.2288
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0066 0.0066
Entamoeba histolytica hypothetical protein 0.0044 0.0066 0.015
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.0002 0.0002
Trypanosoma brucei C-8 sterol isomerase, putative 0.0361 0.1059 0.1947
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0047 0.0076 0.0176
Schistosoma mansoni chromatin regulatory protein sir2 0.0131 0.034 0.034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Echinococcus granulosus caspase 8 0.0044 0.0066 0.0066
Trypanosoma cruzi cysteine peptidase, putative 0.1317 0.4055 0.4048
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0152 0.0407 0.1068
Plasmodium falciparum serine repeat antigen 9 0.0297 0.0859 0.2288
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0043 0.0088
Schistosoma mansoni caspase-7 (C14 family) 0.0184 0.0506 0.0506
Trypanosoma cruzi 20S proteasome subunit 0.0044 0.0067 0.0057
Leishmania major calmodulin, putative 0.0152 0.0407 0.0735
Plasmodium vivax metacaspase 1, putative 0.0044 0.0066 0.0149
Trypanosoma brucei protein I/6 0.0152 0.0407 0.0735
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0786 0.2392 0.2392
Entamoeba histolytica cysteine proteinase, putative 0.0839 0.2559 0.6874
Giardia lamblia Sirtuin type 2 0.0034 0.0035 0.0066
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0214 0.0548
Loa Loa (eye worm) hypothetical protein 0.0139 0.0364 0.0364
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Schistosoma mansoni cpg binding protein 0.003 0.0024 0.0024
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0066 0.0103
Brugia malayi Cell death protein 3 precursor 0.0184 0.0506 0.0506
Trichomonas vaginalis glycogen phosphorylase, putative 0.0114 0.0287 0.0746
Brugia malayi hypothetical protein 0.0042 0.006 0.006
Echinococcus multilocularis caspase 2 0.0184 0.0506 0.0506
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3214 1 1
Giardia lamblia Cathepsin B precursor 0.0297 0.0859 0.2309
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0071 0.0152 0.0381
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0297 0.0859 0.0859
Plasmodium falciparum serine repeat antigen 6 0.0297 0.0859 0.2288
Leishmania major C-8 sterol isomerase-like protein 0.0361 0.1059 0.1947
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0286 0.0826 0.1513
Trypanosoma cruzi kinesin, putative 0.0685 0.2076 0.2068
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0095 0.0226 0.0409
Onchocerca volvulus Peroxidasin homolog 0.0212 0.0592 0.1097
Echinococcus multilocularis histone deacetylase 7 0.0102 0.0249 0.0249
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.0002 0.0002
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0035 0.0066
Loa Loa (eye worm) hypothetical protein 0.0119 0.0302 0.0302
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0232 0.0232
Entamoeba histolytica calmodulin, putative 0.0152 0.0407 0.1068
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0971 0.2972 0.2965
Toxoplasma gondii cathepsin CPL 0.1209 0.3719 0.6883
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0221 0.0623 0.1651
Schistosoma mansoni reticulocalbin 0.0152 0.0407 0.0407
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.036 0.1058 0.1944
Schistosoma mansoni neuronal calcium sensor 0.0152 0.0407 0.0407
Echinococcus granulosus histone deacetylase 6 0.0102 0.0249 0.0249
Mycobacterium ulcerans lipase LipD 0.0036 0.0043 0.0039
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.5498
Onchocerca volvulus 0.0054 0.0098 0.0181
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0971 0.2972 0.2965
Echinococcus multilocularis caspase 8 0.0044 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0119 0.0302 0.0302
Echinococcus granulosus beta-adrenergic receptor kinase 0.0044 0.0066 0.0066
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0592 0.0592
Brugia malayi peptidase family M13 containing protein 0.0023 0.0002 0.0002
Onchocerca volvulus 0.1209 0.3719 0.6889
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Echinococcus multilocularis proteasome (prosome, macropain) 0.0091 0.0216 0.0216
Echinococcus granulosus enteropeptidase 0.0119 0.0302 0.0302
Entamoeba histolytica prolyl oligopeptidase family protein 0.0221 0.0623 0.1651
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Schistosoma mansoni inhibitor of apoptosis protein 0.0189 0.0521 0.0521
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0097 0.0232 0.0232
Schistosoma mansoni chromatin regulatory protein sir2 0.0034 0.0035 0.0035
Brugia malayi Trypsin family protein 0.0119 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0297 0.0859 0.0859
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0214 0.0548
Brugia malayi Trypsin family protein 0.0119 0.0302 0.0302
Giardia lamblia Cathepsin B precursor 0.1199 0.3686 1
Schistosoma mansoni neprilysin 0.0025 0.0007 0.0007
Entamoeba histolytica calcium-binding protein, putative 0.0152 0.0407 0.1068
Loa Loa (eye worm) proteasome subunit beta type 2 0.0044 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.0859 0.2288
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0131 0.034 0.0889
Entamoeba histolytica cysteine protease, putative 0.0297 0.0859 0.2288
Echinococcus granulosus flap endonuclease 1 0.0026 0.0011 0.0011
Loa Loa (eye worm) aspartyl protease 6 0.0042 0.006 0.006
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0066 0.0066
Echinococcus granulosus histone deacetylase 6 0.0102 0.0249 0.0249
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0066 0.0055
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Brugia malayi hypothetical protein 0.0139 0.0364 0.0364
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.0859 0.2288
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3214 1 1
Leishmania major cysteine peptidase A (CPA) 0.1209 0.3719 0.6883
Giardia lamblia Hypothetical protein 0.0131 0.034 0.0897
Loa Loa (eye worm) prolyl oligopeptidase 0.0719 0.2182 0.2182
Plasmodium falciparum plasmepsin VII 0.0042 0.006 0.0134
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0042 0.006 0.006
Echinococcus multilocularis Transglutaminase 0.0364 0.1069 0.1069
Trichomonas vaginalis calmodulin, putative 0.0152 0.0407 0.1068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0066 0.0066
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0152 0.0407 0.1068
Loa Loa (eye worm) histone deacetylase 1 0.0091 0.0214 0.0214
Echinococcus multilocularis calpain family protein 1, d 0.1903 0.5893 0.5893
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0297 0.0859 0.0859
Toxoplasma gondii aldehyde dehydrogenase 0.0135 0.0351 0.0631
Echinococcus multilocularis neuronal calcium sensor 0.0152 0.0407 0.0407
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0189 0.0521 0.0521
Brugia malayi Pre-SET motif family protein 0.0669 0.2025 0.2025
Brugia malayi Cathepsin L-like precursor 0.037 0.1089 0.1089
Schistosoma mansoni hypothetical protein 0.043 0.1275 0.1275
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0066 0.0103
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0297 0.0859 0.0859
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0297 0.0859 0.2288
Trypanosoma cruzi centrin-3 0.0156 0.0418 0.0408
Chlamydia trachomatis glycogen phosphorylase 0.0114 0.0287 0.5
Loa Loa (eye worm) hypothetical protein 0.0119 0.0302 0.0302
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0042 0.006 0.0092
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Trichomonas vaginalis calpain, putative 0.0286 0.0826 0.2198
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0119 0.0302 0.0302
Echinococcus multilocularis neurocalcin 0.0152 0.0407 0.0407
Trypanosoma cruzi caltractin, putative 0.0152 0.0407 0.0396
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0297 0.0859 0.0859
Echinococcus multilocularis chromatin regulatory protein sir2 0.0131 0.034 0.034
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Onchocerca volvulus 0.0042 0.0062 0.0114
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0221 0.0623 0.1651
Onchocerca volvulus 0.003 0.0024 0.0045
Giardia lamblia Cathepsin L-like protease 0.0297 0.0859 0.2309
Echinococcus granulosus cathepsin l1 0.1209 0.3719 0.3719
Mycobacterium tuberculosis Conserved protein 0.0036 0.0043 0.0018
Entamoeba histolytica hypothetical protein 0.0297 0.0859 0.2288
Toxoplasma gondii aspartyl protease ASP1 0.0042 0.006 0.0092
Plasmodium vivax histone deacetylase 2, putative 0.0102 0.0249 0.0643
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Trichomonas vaginalis esterase, putative 0.0036 0.0043 0.0088
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0971 0.2972 0.2965
Toxoplasma gondii subtilisin SUB12 0.003 0.0024 0.0025
Schistosoma mansoni ef hand domain family member A2 0.0152 0.0407 0.0407
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0044 0.0067 0.0067
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0034 0.0035 0.0045
Loa Loa (eye worm) TK/ROR protein kinase 0.0047 0.0076 0.0076
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0044 0.0066 0.0066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0286 0.0826 0.1513
Leishmania major cathepsin L-like protease 0.1209 0.3719 0.6883
Mycobacterium tuberculosis Conserved protein 0.0036 0.0043 0.0018
Mycobacterium leprae Conserved hypothetical protein 0.0364 0.1069 0.4788
Plasmodium falciparum plasmepsin V 0.0042 0.006 0.0134
Toxoplasma gondii aspartyl protease ASP3 0.0203 0.0564 0.1027
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0024 0.0024
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Trypanosoma brucei calpain-like protein, putative 0.0971 0.2972 0.5498
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0097 0.0232 0.0232
Onchocerca volvulus 0.1209 0.3719 0.6889
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0043 0.0043
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0669 0.2025 0.2025
Onchocerca volvulus Cathepsin L homolog 0.0297 0.0859 0.1592
Brugia malayi Papain family cysteine protease containing protein 0.1209 0.3719 0.3719
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0043 0.0088
Echinococcus multilocularis transmembrane protease serine 3 0.0119 0.0302 0.0302
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0152 0.0407 0.1068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0839 0.2559 0.6874
Schistosoma mansoni centrin-related 0.0152 0.0407 0.0407
Plasmodium vivax aspartyl protease, putative 0.0203 0.0564 0.1492
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0667 0.2018 0.3727
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0043 0.0059
Onchocerca volvulus 0.003 0.0024 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0066
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0286 0.0826 0.0826
Brugia malayi calcium-binding protein 0.0152 0.0407 0.0407
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0592 0.0592
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0091 0.0216 0.0387
Onchocerca volvulus Dual oxidase homolog 0.0212 0.0592 0.1097
Echinococcus granulosus neuronal calcium sensor 0.0152 0.0407 0.0407
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Onchocerca volvulus 0.0097 0.0232 0.0429
Echinococcus multilocularis histone deacetylase 3 0.0091 0.0214 0.0214
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0119 0.0302 0.0302
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1745 0.5398 0.5398
Onchocerca volvulus 0.0036 0.0043 0.008
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0091 0.0216 0.0553
Brugia malayi prolyl oligopeptidase family protein 0.0719 0.2182 0.2182
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.0658 0.1333
Plasmodium falciparum peptidase, putative 0.0221 0.0623 0.1651
Schistosoma mansoni calpain-7 (C02 family) 0.0974 0.2983 0.2983
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0116 0.0116
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2741 0.8517 0.8517
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0297 0.0859 0.2288
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0152 0.0407 0.0735
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0228 0.0228
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.036 0.1058 0.1058
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0043 0.0018
Onchocerca volvulus 0.0119 0.0302 0.0559
Plasmodium vivax vivapain-2 0.1209 0.3719 1
Loa Loa (eye worm) calmodulin-like protein 0.0152 0.0407 0.0407
Plasmodium vivax centrin-1, putative 0.0152 0.0407 0.1068
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0097 0.0232 0.041
Trypanosoma brucei calpain, putative 0.0286 0.0826 0.1513
Brugia malayi cathepsin L precursor 0.0297 0.0859 0.0859
Trichomonas vaginalis calcium binding protein, putative 0.0152 0.0407 0.1068
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0297 0.0859 0.2288
Mycobacterium ulcerans zinc metalloprotease 0.0095 0.0226 0.0888
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0024 0.0024
Entamoeba histolytica hypothetical protein 0.0044 0.0066 0.015
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0071 0.0152 0.0262
Toxoplasma gondii PAN domain-containing protein 0.003 0.0024 0.0025
Loa Loa (eye worm) ctsf protein 0.1209 0.3719 0.3719
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0286 0.0826 0.2198
Schistosoma mansoni hypothetical protein 0.0119 0.0302 0.0302
Echinococcus granulosus glycogen phosphorylase 0.0114 0.0287 0.0287
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0297 0.0859 0.2309
Echinococcus granulosus tissue type plasminogen activator 0.0047 0.0076 0.0076
Echinococcus multilocularis calpain 0.0971 0.2972 0.2972
Loa Loa (eye worm) hypothetical protein 0.0297 0.0859 0.0859
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0145 0.0384 0.1007
Loa Loa (eye worm) transcriptional regulator 0.0034 0.0035 0.0035
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0592 0.0592
Brugia malayi hypothetical protein 0.0212 0.0592 0.0592
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.0002 0.0002
Echinococcus granulosus geminin 0.0177 0.0483 0.0483
Schistosoma mansoni neuronal calcium sensor 0.0152 0.0407 0.0407
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Echinococcus multilocularis Glycosyl transferase, family 35 0.0114 0.0287 0.0287
Echinococcus granulosus acylamino acid releasing enzyme 0.0221 0.0623 0.0623
Schistosoma mansoni cathepsin s 0.037 0.1089 0.1089
Loa Loa (eye worm) hypothetical protein 0.037 0.1089 0.1089
Trichomonas vaginalis calcium binding protein, putative 0.0156 0.0418 0.1099
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0044 0.0067 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0062 0.0062
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.0351 0.0351
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0667 0.2018 0.201
Onchocerca volvulus 0.0152 0.0407 0.0753
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.0826 0.0816
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Echinococcus granulosus cathepsin b 0.3214 1 1
Loa Loa (eye worm) proteasome subunit beta type 1 0.0071 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0149
Brugia malayi programmed cell death protein 6 0.0152 0.0407 0.0407
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0071 0.0152 0.0381
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0034 0.0035 0.0066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0135 0.0351 0.0631
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0297 0.0859 0.0859
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Giardia lamblia Cysteine protease 0.0297 0.0859 0.2309
Mycobacterium tuberculosis Hypothetical protein 0.0364 0.1069 0.2214
Mycobacterium leprae Conserved hypothetical protein 0.0364 0.1069 0.4788
Plasmodium falciparum plasmepsin X 0.0203 0.0564 0.1492
Loa Loa (eye worm) hypothetical protein 0.2303 0.7143 0.7143
Trypanosoma cruzi cysteine proteinase, putative 0.0667 0.2018 0.201
Trypanosoma brucei proteasome beta 6 subunit 0.0071 0.0152 0.0262
Trichomonas vaginalis hypothetical protein 0.0286 0.0826 0.2198
Loa Loa (eye worm) hypothetical protein 0.0047 0.0076 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0152 0.0407 0.1068
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0115 0.029 0.029
Plasmodium falciparum cysteine proteinase falcipain 3 0.1209 0.3719 1
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0042 0.006 0.006
Brugia malayi Thioredoxin family protein 0.0364 0.1069 0.1069
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0044 0.0066 0.0066
Giardia lamblia Cathepsin B precursor 0.1199 0.3686 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0297 0.0859 0.2288
Trichomonas vaginalis calmodulin, putative 0.0152 0.0407 0.1068
Leishmania major phospholipase c-like protein 0.0152 0.0407 0.0735
Entamoeba histolytica cysteine protease, putative 0.1209 0.3719 1
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0149
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0135 0.0351 0.0676
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0189 0.0521 0.0521
Brugia malayi Angiotensin-converting enzyme family protein 0.0603 0.1819 0.1819
Loa Loa (eye worm) prolyl oligopeptidase 0.0221 0.0623 0.0623
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0152 0.0407 0.0407
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0062
Echinococcus granulosus glycoprotein Antigen 5 0.0119 0.0302 0.0302
Leishmania major calmodulin-like protein 0.0152 0.0407 0.0735
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Onchocerca volvulus 0.003 0.0024 0.0045
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0043 0.0032
Echinococcus granulosus tumor protein p63 0.0381 0.1123 0.1123
Onchocerca volvulus 0.0297 0.0859 0.1592
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0152 0.0407 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.015
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0062 0.0138
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.0859 0.2288
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0043 0.0043
Toxoplasma gondii hypothetical protein 0.0286 0.0826 0.1513
Entamoeba histolytica hypothetical protein, conserved 0.0221 0.0623 0.1651
Schistosoma mansoni hypothetical protein 0.0189 0.0521 0.0521
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0297 0.0859 0.0859
Echinococcus granulosus neurocalcin 0.0152 0.0407 0.0407
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1209 0.3719 0.3719
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Onchocerca volvulus Glycogen phosphorylase homolog 0.0114 0.0287 0.0533
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.2965
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0066 0.0066
Plasmodium vivax vivapain-2 0.1209 0.3719 1
Trichomonas vaginalis calcium binding protein, putative 0.0152 0.0407 0.1068
Loa Loa (eye worm) calpain family protein 1 0.2589 0.804 0.804
Toxoplasma gondii troponin c, isotype gamma, putative 0.0152 0.0407 0.0735
Brugia malayi Peroxidasin 0.0212 0.0592 0.0592
Trypanosoma cruzi histone deacetylase, putative 0.0044 0.0067 0.0056
Trichomonas vaginalis calmodulin, putative 0.0152 0.0407 0.1068
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0971 0.2972 0.5498
Leishmania major cathepsin L-like protease 0.1209 0.3719 0.6883
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Toxoplasma gondii microneme protein MIC17A 0.003 0.0024 0.0025
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.072 0.2185 0.4036
Brugia malayi Proteasome A-type and B-type family protein 0.0091 0.0216 0.0216
Entamoeba histolytica grainin 2 0.0156 0.0418 0.1099
Plasmodium falciparum histone deacetylase, putative 0.0102 0.0249 0.0643
Echinococcus granulosus calcium uptake protein 1 0.0155 0.0414 0.0414
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0043 0.0018
Toxoplasma gondii PAN domain-containing protein 0.003 0.0024 0.0025
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0091 0.0216 0.0805
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0066 0.0066
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0297 0.0859 0.2288
Plasmodium falciparum serine repeat antigen 2 0.0297 0.0859 0.2288
Entamoeba histolytica cysteine proteinase, putative 0.0667 0.2018 0.5415
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0228 0.0228
Toxoplasma gondii EFHC1, putative 0.0152 0.0407 0.0735
Entamoeba histolytica glycogen phosphorylase, putative 0.0114 0.0287 0.0746
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0071 0.0152 0.0141
Schistosoma mansoni memapsin-2 (A01 family) 0.0497 0.1488 0.1488
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0297 0.0859 0.0859
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0297 0.0859 0.2288
Entamoeba histolytica glycogen phosphorylase, putative 0.0114 0.0287 0.0746
Trypanosoma brucei calpain-like protein, putative 0.0971 0.2972 0.5498
Brugia malayi Cytochrome P450 family protein 0.0036 0.0043 0.0043
Onchocerca volvulus 0.0364 0.1069 0.198
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0066 0.0066
Giardia lamblia Cathepsin L precursor 0.0297 0.0859 0.2309
Trypanosoma brucei histone deacetylase 2 0.0044 0.0067 0.0104
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0066 0.0066
Plasmodium vivax unspecified product 0.0667 0.2018 0.5415
Giardia lamblia Cathepsin L precursor 0.0297 0.0859 0.2309
Loa Loa (eye worm) calpain 0.0971 0.2972 0.2972
Echinococcus multilocularis peroxidasin 0.0212 0.0592 0.0592
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0971 0.2972 0.2965
Brugia malayi hypothetical protein 0.0141 0.037 0.037
Loa Loa (eye worm) calpain D 0.0286 0.0826 0.0826
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0034 0.0035 0.0035
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1199 0.3686 0.368
Brugia malayi aspartic protease BmAsp-2, identical 0.0042 0.006 0.006
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0043 0.0033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1209 0.3719 0.3719
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0024 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0062
Giardia lamblia Cathepsin L precursor 0.0297 0.0859 0.2309
Schistosoma mansoni chromatin regulatory protein sir2 0.0131 0.034 0.034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0361 0.1059 0.1059
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0091 0.0216 0.0216
Brugia malayi gamma-secretase subunit aph-1 0.0258 0.0739 0.0739
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0232 0.0232
Echinococcus multilocularis histone deacetylase 8 0.0044 0.0067 0.0067
Echinococcus granulosus gamma secretase subunit aph 1 0.0258 0.0739 0.0739
Trichomonas vaginalis myosin light chain 1, putative 0.0152 0.0407 0.1068
Entamoeba histolytica calpain large subunit domain III containing protein 0.0685 0.2076 0.557
Loa Loa (eye worm) hypothetical protein 0.037 0.1089 0.1089
Loa Loa (eye worm) hypothetical protein 0.0065 0.0132 0.0132
Entamoeba histolytica cysteine protease, putative 0.0297 0.0859 0.2288
Onchocerca volvulus 0.0056 0.0104 0.0193
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Toxoplasma gondii histone deacetylase HDAC5 0.0044 0.0067 0.0105
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0066
Schistosoma mansoni cpg binding protein 0.0032 0.0029 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0623 0.0613
Giardia lamblia Cysteine protease 0.0297 0.0859 0.2309
Loa Loa (eye worm) hypothetical protein 0.0152 0.0407 0.0407
Echinococcus granulosus calpain 0.0971 0.2972 0.2972
Plasmodium falciparum cysteine repeat modular protein 1 0.0047 0.0076 0.0176
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0228 0.0228
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0297 0.0859 0.0859
Trypanosoma brucei metacaspase MCA3 0.0044 0.0066 0.0103
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0044 0.0067 0.0067
Onchocerca volvulus 0.1209 0.3719 0.6889
Giardia lamblia Hypothetical protein 0.0297 0.0859 0.2309
Schistosoma mansoni hypothetical protein 0.0152 0.0407 0.0407
Schistosoma mansoni microtubule-associated protein tau 0.1556 0.4804 0.4804
Brugia malayi calpain 7 0.0971 0.2972 0.2972
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0145 0.0384 0.0384
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0049 0.0084 0.0228
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.0826 0.0816
Trypanosoma brucei histone deacetylase 4 0.0102 0.0249 0.0442
Brugia malayi PXA domain containing protein 0.0044 0.0066 0.0066
Entamoeba histolytica cysteine proteinase, putative 0.1209 0.3719 1
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0048 0.0079 0.0079
Echinococcus granulosus programmed cell death protein 0.0156 0.0418 0.0418
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0592 0.0592
Echinococcus granulosus proteasome prosome macropain 0.0091 0.0216 0.0216
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Echinococcus granulosus cpg binding protein 0.0032 0.0029 0.0029
Trichomonas vaginalis calcium binding protein, putative 0.0152 0.0407 0.1068
Trypanosoma brucei histone deacetylase 1 0.0091 0.0214 0.0377
Echinococcus multilocularis histone deacetylase 6 0.0108 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Plasmodium falciparum plasmepsin III 0.0042 0.006 0.0134
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0263 0.0755 0.0755
Brugia malayi Calmodulin-like protein 0.0152 0.0407 0.0407
Onchocerca volvulus 0.003 0.0024 0.0045
Loa Loa (eye worm) EF hand family protein 0.0152 0.0407 0.0407
Brugia malayi transcriptional regulator, Sir2 family protein 0.0131 0.034 0.034
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0043 0.0018
Mycobacterium leprae probable zinc metalloprotease 0.0095 0.0226 0.0853
Giardia lamblia Cathepsin B precursor 0.0297 0.0859 0.2309
Plasmodium vivax unspecified product 0.037 0.1089 0.2907
Schistosoma mansoni histone deacetylase 0.0091 0.0214 0.0214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Toxoplasma gondii PAN domain-containing protein 0.003 0.0024 0.0025
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0062 0.0062
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0297 0.0859 0.2288
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0043 0.0018
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0221 0.0623 0.1137
Brugia malayi Flap endonuclease-1 0.0026 0.0011 0.0011
Echinococcus multilocularis dnaJ subfamily B 0.043 0.1275 0.1275
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0066
Brugia malayi hypothetical protein 0.0044 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Brugia malayi Histone deacetylase family protein 0.0102 0.0249 0.0249
Brugia malayi cathepsin L-like precursor 0.0839 0.2559 0.2559
Trypanosoma cruzi cruzipain precursor, putative 0.1317 0.4055 0.4048
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0066 0.0103
Echinococcus granulosus histone deacetylase 1 0.0091 0.0214 0.0214
Toxoplasma gondii kringle domain-containing protein 0.0047 0.0076 0.0121
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0062
Onchocerca volvulus 0.0212 0.0592 0.1097
Brugia malayi Cathepsin L-like precursor 0.0839 0.2559 0.2559
Plasmodium vivax serine-repeat antigen (SERA) 0.0297 0.0859 0.2288
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Brugia malayi regulator of G-protein signaling egl-10 0.0044 0.0066 0.0066
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0067 0.0153
Toxoplasma gondii histone deacetylase SIR2 0.0034 0.0035 0.0045
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0286 0.0826 0.2198
Trypanosoma cruzi cysteine peptidase, putative 0.1317 0.4055 0.4048
Echinococcus multilocularis calcium uptake protein 1 0.0155 0.0414 0.0414
Schistosoma mansoni calpain C (C02 family) 0.0971 0.2972 0.2972
Echinococcus multilocularis histone deacetylase 6 0.0102 0.0249 0.0249
Echinococcus granulosus caspase 3 0.0071 0.0153 0.0153
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0043 0.0033
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0152 0.0407 0.1068
Mycobacterium ulcerans beta-lactamase 0.0036 0.0043 0.0039
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0066 0.0066
Onchocerca volvulus 0.0036 0.0043 0.008
Trypanosoma brucei hypothetical protein, conserved 0.0152 0.0407 0.0735
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0066 0.0066
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0062 0.0138
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1199 0.3686 0.6823
Brugia malayi calpain family protein 1 0.2589 0.804 0.804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0839 0.2559 0.6874
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0034 0.0035 0.0066
Brugia malayi EF hand family protein 0.0152 0.0407 0.0407
Leishmania major calmodulin-like protein 0.0152 0.0407 0.0735
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0043 0.0043
Loa Loa (eye worm) calpain 5 0.0685 0.2076 0.2076
Trypanosoma brucei calpain-like protein, putative 0.0971 0.2972 0.5498
Trypanosoma brucei calmodulin, putative 0.0155 0.0414 0.0749
Schistosoma mansoni flap endonuclease-1 0.0023 0.0003 0.0003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0135 0.0351 0.0351
Brugia malayi NAD-dependent deacetylase SIRT1 0.0145 0.0384 0.0384
Echinococcus granulosus cathepsin l1 0.0839 0.2559 0.2559
Toxoplasma gondii calmodulin CAM1 0.0155 0.0414 0.0749
Giardia lamblia Cathepsin B precursor 0.0297 0.0859 0.2309
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0221 0.0623 0.1651
Trichomonas vaginalis conserved hypothetical protein 0.0297 0.0859 0.2288
Plasmodium falciparum proteasome subunit beta type-5 0.0091 0.0216 0.0553
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0131 0.034 0.033
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0066
Echinococcus granulosus cathepsin L 0.0667 0.2018 0.2018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.0826 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.0859 0.2288
Trypanosoma cruzi histone deacetylase 1, putative 0.0091 0.0214 0.0203
Onchocerca volvulus 0.017 0.0463 0.0858
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Plasmodium vivax NAD-dependent deacetylase, putative 0.0034 0.0035 0.0066
Trichomonas vaginalis calmodulin, putative 0.0155 0.0414 0.1089
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0043 0.0039
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0044 0.0067 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0149
Echinococcus granulosus calpain A 0.0971 0.2972 0.2972
Trypanosoma brucei Calpain-like protein 2 0.0286 0.0826 0.1513
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3214 1 1
Giardia lamblia Glycogen phosphorylase 0.0114 0.0287 0.0753
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0297 0.0859 0.2288
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0221 0.0623 0.0623
Brugia malayi Papain family cysteine protease containing protein 0.0297 0.0859 0.0859
Echinococcus multilocularis cysteine protease 0.1209 0.3719 0.3719
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0066 0.0149
Schistosoma mansoni histone deacetylase 4 5 0.0102 0.0249 0.0249
Onchocerca volvulus Cathepsin L homolog 0.1209 0.3719 0.6889
Loa Loa (eye worm) hypothetical protein 0.0184 0.0507 0.0507
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0149
Plasmodium vivax SET domain protein, putative 0.0097 0.0232 0.0596
Trypanosoma brucei SIR2-like protein 4, putative 0.0034 0.0035 0.0045
Trichomonas vaginalis calmodulin, putative 0.0152 0.0407 0.1068
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0066 0.0066
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0297 0.0859 0.2309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Brugia malayi prolyl oligopeptidase family protein 0.1745 0.5398 0.5398
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0035 0.0066
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0152 0.0407 0.0396
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1209 0.3719 1
Echinococcus multilocularis histone deacetylase 1 0.0091 0.0214 0.0214
Leishmania major hypothetical protein, conserved 0.0047 0.0076 0.0121
Schistosoma mansoni histone deacetylase 0.0091 0.0214 0.0214
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0145 0.0384 0.0384
Brugia malayi calpain D 0.0286 0.0826 0.0826
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Onchocerca volvulus 0.0212 0.0592 0.1097
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0043 0.0043
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0297 0.0859 0.2288
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0062 0.0138
Schistosoma mansoni cathepsin F (C01 family) 0.1209 0.3719 0.3719
Echinococcus multilocularis programmed cell death protein 0.0156 0.0418 0.0418
Echinococcus granulosus survival motor neuron protein 1 0.0263 0.0755 0.0755
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0091 0.0216 0.0205
Trypanosoma cruzi cysteine peptidase, putative 0.1209 0.3719 0.3712
Schistosoma mansoni centrin 0.0152 0.0407 0.0407
Toxoplasma gondii hypothetical protein 0.0221 0.0623 0.1137
Entamoeba histolytica hypothetical protein, conserved 0.0034 0.0035 0.0066
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.036 0.1058 0.1944
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0286 0.0826 0.1513
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0297 0.0859 0.2288
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0071 0.0152 0.0141
Trypanosoma brucei cysteine peptidase C (CPC) 0.1199 0.3686 0.6823
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0035 0.0066
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0297 0.0859 0.2288
Onchocerca volvulus Peroxidasin homolog 0.0212 0.0592 0.1097
Schistosoma mansoni calpain (C02 family) 0.0971 0.2972 0.2972
Plasmodium falciparum metacaspase 1 0.0044 0.0066 0.0149
Plasmodium falciparum histone deacetylase 2 0.0102 0.0249 0.0643
Trichomonas vaginalis glycogen phosphorylase, putative 0.0114 0.0287 0.0746
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0036 0.0043 0.0035
Onchocerca volvulus 0.003 0.0024 0.0045
Plasmodium vivax proteasome subunit beta type-5, putative 0.0091 0.0216 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Brugia malayi Pre-SET motif family protein 0.0097 0.0232 0.0232
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0592 0.0592
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0024 0.0024
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0297 0.0859 0.0859
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Echinococcus multilocularis inhibitor of apoptosis protein 0.0189 0.0521 0.0521
Schistosoma mansoni hypothetical protein 0.0119 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0119 0.0302 0.0302
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0667 0.2018 0.2018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Echinococcus granulosus centrin 2 0.0152 0.0407 0.0407
Echinococcus multilocularis calmodulin 0.0152 0.0407 0.0407
Mycobacterium tuberculosis Probable peptidase 0.072 0.2185 0.4604
Trypanosoma cruzi cruzipain precursor, putative 0.037 0.1089 0.1079
Schistosoma mansoni cathepsin F (C01 family) 0.0839 0.2559 0.2559
Loa Loa (eye worm) hypothetical protein 0.0221 0.0623 0.0623
Entamoeba histolytica cysteine proteinase, putative 0.0667 0.2018 0.5415
Echinococcus multilocularis expressed protein 0.0851 0.2596 0.2596
Trypanosoma brucei oligopeptidase b 0.072 0.2185 0.4036
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0091 0.0216 0.0205
Brugia malayi MH2 domain containing protein 0.013 0.0335 0.0335
Trypanosoma brucei centrin, putative 0.0152 0.0407 0.0735
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0297 0.0859 0.2309
Mycobacterium ulcerans putative transglutaminase-like protein 0.0364 0.1069 0.4808
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0177 0.0483 0.0483
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0155 0.0414 0.0404
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Echinococcus granulosus histone deacetylase 3 0.0091 0.0214 0.0214
Schistosoma mansoni cathepsin D (A01 family) 0.0229 0.0648 0.0648
Giardia lamblia Hypothetical protein 0.0155 0.0414 0.1098
Toxoplasma gondii ABC1 family protein 0.0036 0.0043 0.0061
Echinococcus granulosus histone lysine methyltransferase setb 0.0097 0.0232 0.0232
Plasmodium falciparum plasmepsin VI 0.0042 0.006 0.0134
Schistosoma mansoni caspase-7 (C14 family) 0.0115 0.029 0.029
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0189 0.0521 0.0521
Echinococcus granulosus calpain 7 C02 family 0.0971 0.2972 0.2972
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0097 0.0232 0.0232
Trypanosoma brucei calmodulin, putative 0.0152 0.0407 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.015
Onchocerca volvulus 0.1209 0.3719 0.6889
Trypanosoma brucei kinesin, putative 0.0685 0.2076 0.3834
Echinococcus granulosus caspase 0.0115 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0839 0.2559 0.2559
Toxoplasma gondii cathepsin CPC2 0.0297 0.0859 0.1575
Brugia malayi proteasome subunit beta type 1 0.0071 0.0152 0.0152
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0286 0.0826 0.0816
Loa Loa (eye worm) histone deacetylase 3 0.0091 0.0214 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.015
Brugia malayi prolyl oligopeptidase family protein 0.0221 0.0623 0.0623
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Toxoplasma gondii prolyl endopeptidase 0.1745 0.5398 1
Giardia lamblia Cathepsin L precursor 0.0297 0.0859 0.2309
Loa Loa (eye worm) hypothetical protein 0.007 0.0149 0.0149
Echinococcus multilocularis cathepsin b 0.3214 1 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.2965
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0091 0.0216 0.0553
Giardia lamblia Proteasome subunit beta type 2 0.0044 0.0067 0.0154
Brugia malayi Pepsin A precursor 0.0042 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0042 0.006 0.006
Plasmodium vivax plasmepsin IV, putative 0.0042 0.006 0.0134
Trypanosoma cruzi calmodulin, putative 0.0152 0.0407 0.0396
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Schistosoma mansoni histone deacetylase hda2 0.0108 0.0269 0.0269
Onchocerca volvulus Prolyl endopeptidase homolog 0.1745 0.5398 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0297 0.0859 0.0859
Toxoplasma gondii microneme protein MIC17C 0.003 0.0024 0.0025
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0024 0.0024
Onchocerca volvulus 0.003 0.0024 0.0044
Brugia malayi cathepsin Z-like cysteine proteinase 0.0297 0.0859 0.0859
Schistosoma mansoni hypothetical protein 0.0286 0.0826 0.0826
Echinococcus granulosus calpain A 0.2743 0.8525 0.8525
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0062 0.0062
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0044 0.0067 0.0153
Trypanosoma brucei cysteine peptidase, putative 0.0286 0.0826 0.1513
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Schistosoma mansoni cathepsin S (C01 family) 0.0297 0.0859 0.0859
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0145 0.0384 0.1007
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0214 0.0548
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0131 0.034 0.034
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0076 0.0065
Echinococcus multilocularis centrin 2 0.0152 0.0407 0.0407
Trypanosoma cruzi histone deacetylase, putative 0.0102 0.0249 0.0239
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0066
Echinococcus multilocularis beta adrenergic receptor kinase 0.0044 0.0066 0.0066
Leishmania major hypothetical protein, conserved 0.0155 0.0414 0.0749
Echinococcus multilocularis calbindin 32 0.0155 0.0414 0.0414
Schistosoma mansoni neuronal calcium sensor 0.0152 0.0407 0.0407
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0297 0.0859 0.2288
Loa Loa (eye worm) hypothetical protein 0.0095 0.0226 0.0226
Trypanosoma brucei histone deacetylase, putative 0.0102 0.0249 0.0442
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0034 0.0035 0.0066
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0286 0.0826 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1209 0.3719 1
Loa Loa (eye worm) trypsin family protein 0.0119 0.0302 0.0302
Trypanosoma cruzi oligopeptidase b 0.072 0.2185 0.2176
Echinococcus multilocularis calpain A 0.2743 0.8525 0.8525
Loa Loa (eye worm) hypothetical protein 0.1745 0.5398 0.5398
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0228 0.0228
Leishmania major cathepsin L-like protease 0.1317 0.4055 0.7507
Onchocerca volvulus 0.1209 0.3719 0.6889
Onchocerca volvulus Chorion peroxidase homolog 0.0212 0.0592 0.1097
Plasmodium falciparum centrin-1 0.0152 0.0407 0.1068
Trypanosoma cruzi I/6 autoantigen, putative 0.0152 0.0407 0.0396
Brugia malayi histone deacetylase 1 (HD1) 0.0091 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0097 0.0232 0.0232
Plasmodium vivax calpain, putative 0.0971 0.2972 0.7987
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Brugia malayi Kringle domain containing protein 0.0047 0.0076 0.0076
Onchocerca volvulus Deterin homolog 0.0189 0.0521 0.0966
Echinococcus granulosus inhibitor of apoptosis protein 0.0189 0.0521 0.0521
Onchocerca volvulus 0.0042 0.006 0.0112
Echinococcus granulosus calmodulin 0.0152 0.0407 0.0407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.0859 0.2288
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0152 0.0407 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1199 0.3686 0.9913
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0189 0.0521 0.0521
Trypanosoma brucei I/6 autoantigen 0.0152 0.0407 0.0735
Loa Loa (eye worm) hypothetical protein 0.0189 0.0521 0.0521
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1199 0.3686 0.3686
Leishmania major cathepsin L-like protease 0.1317 0.4055 0.7507
Trypanosoma cruzi prolyl endopeptidase 0.1745 0.5398 0.5393
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0119 0.0302 0.0302
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.0859 0.2288
Echinococcus multilocularis cathepsin b 0.3214 1 1
Loa Loa (eye worm) histone deacetylase 11 0.0044 0.0067 0.0067
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0035 0.0066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.2965
Trypanosoma cruzi I/6 autoantigen, putative 0.0152 0.0407 0.0396
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.072 0.2185 0.2176
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0286 0.0826 0.2198
Onchocerca volvulus 0.003 0.0024 0.0045
Echinococcus multilocularis cysteine protease 0.1209 0.3719 0.3719
Brugia malayi cathepsin Z-like cysteine proteinase 0.0297 0.0859 0.0859
Echinococcus multilocularis prolyl endopeptidase 0.1745 0.5398 0.5398
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0228 0.0228
Schistosoma mansoni histone deacetylase 4 5 0.0102 0.0249 0.0249
Brugia malayi Trypsin family protein 0.0119 0.0302 0.0302
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0079 0.0079
Brugia malayi Blistered cuticle protein 3 0.0212 0.0592 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0297 0.0859 0.2288
Echinococcus granulosus cathepsin l cysteine peptidase 0.1209 0.3719 0.3719
Brugia malayi beta-lactamase 0.0036 0.0043 0.0043
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Brugia malayi PXA domain containing protein 0.0044 0.0066 0.0066
Trypanosoma brucei metacaspase MCA2 0.0044 0.0066 0.0103
Echinococcus granulosus transmembrane protease serine 3 0.0119 0.0302 0.0302
Schistosoma mansoni rab 0.0152 0.0407 0.0407
Mycobacterium tuberculosis Conserved hypothetical protein 0.0364 0.1069 0.2214
Leishmania major calcineurin B subunit, putative 0.0152 0.0407 0.0735
Plasmodium falciparum plasmepsin IV 0.0042 0.006 0.0134
Loa Loa (eye worm) hypothetical protein 0.0189 0.0521 0.0521
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0043 0.0043
Plasmodium vivax hypothetical protein, conserved 0.0221 0.0623 0.1651
Echinococcus granulosus chromatin regulatory protein sir2 0.0131 0.034 0.034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Schistosoma mansoni chromatin regulatory protein sir2 0.0034 0.0035 0.0035
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Giardia lamblia Cathepsin B precursor 0.1199 0.3686 1
Echinococcus multilocularis calpain 7 (C02 family) 0.0971 0.2972 0.2972
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0024 0.0024
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.0219 0.0219
Echinococcus granulosus histone deacetylase 0.0102 0.0249 0.0249
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0145 0.0384 0.1007
Leishmania major i/6 autoantigen-like protein 0.0152 0.0407 0.0735
Giardia lamblia Serine peptidase, putative 0.0042 0.0062 0.0139
Schistosoma mansoni caspase-3 (C14 family) 0.0115 0.029 0.029
Schistosoma mansoni glycogen phosphorylase 0.0114 0.0287 0.0287
Trypanosoma cruzi centrin, putative 0.0156 0.0418 0.0408
Onchocerca volvulus 0.0155 0.0414 0.0768
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0091 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0141 0.037 0.037
Onchocerca volvulus 0.0036 0.0043 0.008
Brugia malayi Cathepsin L-like precursor 0.0839 0.2559 0.2559
Leishmania major oligopeptidase b 0.072 0.2185 0.4036
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2741 0.8517 0.8517
Trichomonas vaginalis set domain proteins, putative 0.0761 0.2315 0.6213
Loa Loa (eye worm) hypothetical protein 0.1903 0.5893 0.5893
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0034 0.0035 0.0035
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0044 0.0066 0.0066
Onchocerca volvulus 0.003 0.0024 0.0045
Schistosoma mansoni chromatin regulatory protein sir2 0.0034 0.0035 0.0035
Trypanosoma brucei hypothetical protein 0.0286 0.0826 0.1513
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0043 0.0061
Plasmodium vivax serine-repeat antigen (SERA) 0.0297 0.0859 0.2288
Brugia malayi Protein kinase domain containing protein 0.0047 0.0076 0.0076
Plasmodium falciparum plasmepsin II 0.0042 0.006 0.0134
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0002 0.0002
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0042 0.006 0.0092
Brugia malayi Papain family cysteine protease containing protein 0.0297 0.0859 0.0859
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0971 0.2972 0.2965
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0049 0.0084 0.0105
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.0826 0.0816
Loa Loa (eye worm) hypothetical protein 0.1617 0.4997 0.4997
Leishmania major cathepsin L-like protease 0.1209 0.3719 0.6883
Loa Loa (eye worm) cysteine protease 0.1209 0.3719 0.3719
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0228 0.0228
Giardia lamblia Alanyl dipeptidyl peptidase 0.0221 0.0623 0.1666
Toxoplasma gondii PAN domain-containing protein 0.003 0.0024 0.0025
Toxoplasma gondii histone deacetylase HDAC2 0.0091 0.0214 0.0377
Plasmodium vivax hypothetical protein, conserved 0.0155 0.0414 0.1089
Schistosoma mansoni calmodulin 0.0152 0.0407 0.0407
Trypanosoma brucei centrin, putative 0.0152 0.0407 0.0735
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0297 0.0859 0.2288
Plasmodium falciparum serine repeat antigen 3 0.0297 0.0859 0.2288
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0297 0.0859 0.2309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Plasmodium falciparum calpain 0.0286 0.0826 0.2198
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.0826 0.0816
Plasmodium falciparum serine repeat antigen 7 0.0297 0.0859 0.2288
Giardia lamblia Alanyl dipeptidyl peptidase 0.0221 0.0623 0.1666
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0214 0.0548
Echinococcus multilocularis tumor protein p63 0.0381 0.1123 0.1123
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Brugia malayi Eukaryotic aspartyl protease family protein 0.0042 0.006 0.006
Toxoplasma gondii hypothetical protein 0.003 0.0024 0.0025
Brugia malayi CXXC zinc finger family protein 0.003 0.0024 0.0024
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0152 0.0407 0.1068
Loa Loa (eye worm) hypothetical protein 0.0839 0.2559 0.2559
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0066 0.0066
Plasmodium falciparum serine repeat antigen 5 0.0297 0.0859 0.2288
Trichomonas vaginalis conserved hypothetical protein 0.0297 0.0859 0.2288
Leishmania major hypothetical protein, unknown function 0.0286 0.0826 0.1513
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0066 0.0066
Giardia lamblia Cysteine protease 0.0297 0.0859 0.2309
Onchocerca volvulus 0.1209 0.3719 0.6889
Onchocerca volvulus 0.0119 0.0302 0.0559
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Trypanosoma brucei prolyl oligopeptidase, putative 0.072 0.2185 0.4036
Echinococcus multilocularis cathepsin L cysteine protease 0.1209 0.3719 0.3719
Plasmodium vivax histone deacetylase, putative 0.0102 0.0249 0.0643
Echinococcus multilocularis geminin 0.0177 0.0483 0.0483
Schistosoma mansoni glycogen phosphorylase 0.0114 0.0287 0.0287
Schistosoma mansoni hypothetical protein 0.0054 0.0098 0.0098
Echinococcus multilocularis microtubule associated protein 2 0.1556 0.4804 0.4804
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0131 0.034 0.0889
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0221 0.0623 0.1137
Echinococcus granulosus microtubule associated protein 2 0.1556 0.4804 0.4804
Toxoplasma gondii histone deacetylase HDAC3 0.0091 0.0214 0.0377
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0152 0.0407 0.0407
Entamoeba histolytica cysteine protease, putative 0.0297 0.0859 0.2288
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0043 0.0088
Giardia lamblia Cathepsin B precursor 0.0297 0.0859 0.2309
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.0002 0.0002
Echinococcus multilocularis hypothetical protein 0.0971 0.2972 0.2972
Mycobacterium tuberculosis Conserved hypothetical protein 0.0364 0.1069 0.2214
Toxoplasma gondii histone deacetylase SIR2-like 0.0034 0.0035 0.0045
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0719 0.2182 0.4042
Trypanosoma cruzi Aph-1 protein, putative 0.0101 0.0245 0.0234
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0667 0.2018 0.5415
Loa Loa (eye worm) programmed cell death protein 6 0.0155 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0062
Echinococcus granulosus Glycosyl transferase family 35 0.0114 0.0287 0.0287
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Onchocerca volvulus 0.0152 0.0407 0.0753
Brugia malayi calpain 5 0.0685 0.2076 0.2076
Loa Loa (eye worm) transcriptional regulator 0.0034 0.0035 0.0035
Loa Loa (eye worm) calpain family protein 1 0.1903 0.5893 0.5893
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1524 0.4704 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0297 0.0859 0.0849
Trypanosoma cruzi Aph-1 protein, putative 0.0101 0.0245 0.0234
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0947 0.2896 0.2888
Loa Loa (eye worm) sirtuin 4 0.0034 0.0035 0.0035
Trypanosoma brucei centrin-3 0.0156 0.0418 0.0756
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0141 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.015
Schistosoma mansoni hypothetical protein 0.0364 0.1069 0.1069
Leishmania major hypothetical protein, conserved 0.0036 0.0043 0.0061
Onchocerca volvulus 0.0047 0.0076 0.0141
Onchocerca volvulus 0.0119 0.0302 0.0559
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.5498
Loa Loa (eye worm) hypothetical protein 0.0044 0.0067 0.0067
Schistosoma mansoni cathepsin F (C01 family) 0.1209 0.3719 0.3719
Onchocerca volvulus 0.003 0.0024 0.0045
Echinococcus granulosus calumenin 0.0155 0.0414 0.0414
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Echinococcus granulosus Dipeptidyl peptidase 9 0.036 0.1058 0.1058
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0011 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Brugia malayi Papain family cysteine protease containing protein 0.0667 0.2018 0.2018
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0066 0.0066
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0066 0.0103
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0062 0.0062
Mycobacterium ulcerans transglutaminase family protein 0.0364 0.1069 0.4808
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0066 0.0066
Trypanosoma cruzi cysteine peptidase, putative 0.0667 0.2018 0.201
Echinococcus granulosus Transglutaminase 0.0364 0.1069 0.1069
Schistosoma mansoni glycogen phosphorylase 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Schistosoma mansoni chromatin regulatory protein sir2 0.0145 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0131 0.034 0.033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0351 0.1469
Trypanosoma cruzi histone deacetylase 1, putative 0.0091 0.0214 0.0203
Loa Loa (eye worm) hypothetical protein 0.0297 0.0859 0.0859
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0034 0.0035 0.0066
Onchocerca volvulus 0.0119 0.0302 0.0559
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.2997 0.2997
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0044 0.0066 0.0066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0214 0.0548
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0084 0.0198
Plasmodium vivax proteasome subunit beta type-1, putative 0.0071 0.0152 0.0381
Mycobacterium tuberculosis Long conserved protein 0.0364 0.1069 0.2214
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0971 0.2972 0.2965
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0095 0.0226 0.0226
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0056 0.0104 0.0104
Onchocerca volvulus 0.0047 0.0076 0.0141
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2589 0.804 0.804
Brugia malayi A-kinase anchor protein 10, precursor 0.0044 0.0066 0.0066
Echinococcus granulosus EF hand domain containing family member A2 0.0152 0.0407 0.0407
Loa Loa (eye worm) hypothetical protein 0.0145 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0119 0.0302 0.0302
Trypanosoma cruzi centrin, putative 0.0156 0.0418 0.0408
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Loa Loa (eye worm) RGS-3 protein 0.0044 0.0066 0.0066
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0066 0.0066
Schistosoma mansoni cathepsin D (A01 family) 0.0229 0.0648 0.0648
Brugia malayi hypothetical protein 0.0042 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Trypanosoma brucei Aph-1 protein, putative 0.0101 0.0245 0.0435
Loa Loa (eye worm) hypothetical protein 0.007 0.0149 0.0149
Trypanosoma brucei calpain, putative 0.0286 0.0826 0.1513
Entamoeba histolytica protein kinase, putative 0.0685 0.2076 0.557
Onchocerca volvulus 0.0141 0.037 0.0685
Trichomonas vaginalis centrin, putative 0.0152 0.0407 0.1068
Brugia malayi EF hand family protein 0.0155 0.0414 0.0414
Brugia malayi prolyl oligopeptidase family protein 0.0221 0.0623 0.0623
Schistosoma mansoni cpg binding protein 0.0032 0.0029 0.0029
Brugia malayi prolyl oligopeptidase family protein 0.036 0.1058 0.1058
Plasmodium vivax aspartyl protease, putative 0.0203 0.0564 0.1492
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.0351 0.0351
Leishmania major calpain protease-like protein 0.0286 0.0826 0.1513
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.006 0.006
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.072 0.2185 0.4604
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0119 0.0302 0.0302
Schistosoma mansoni hypothetical protein 0.0047 0.0076 0.0076
Loa Loa (eye worm) fibroinase 0.1209 0.3719 0.3719
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0297 0.0859 0.2288
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0361 0.1059 0.1059
Loa Loa (eye worm) hypothetical protein 0.0095 0.0226 0.0226
Brugia malayi Trypsin family protein 0.0119 0.0302 0.0302
Schistosoma mansoni hypothetical protein 0.0177 0.0483 0.0483
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0152 0.0407 0.0396
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0066
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Echinococcus granulosus calpain 5 0.0971 0.2972 0.2972
Entamoeba histolytica cysteine proteinase, putative 0.1209 0.3719 1
Leishmania major centrin, putative,caltractin, putative 0.0152 0.0407 0.0735
Plasmodium falciparum plasmepsin VIII, putative 0.0042 0.006 0.0134
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Onchocerca volvulus Peroxidase homolog 0.0212 0.0592 0.1097
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0007 0.0007
Trypanosoma cruzi oligopeptidase b 0.072 0.2185 0.2176
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0221 0.0623 0.0623
Schistosoma mansoni z-protein (S1r protein) 0.0044 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.017 0.0463 0.0463
Toxoplasma gondii microneme protein MIC4 0.003 0.0024 0.0025
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0066 0.0066
Echinococcus granulosus apoptotic protease activating factor 1 0.0141 0.037 0.037
Toxoplasma gondii calcium-dependent protein kinase 0.0155 0.0414 0.0749
Trichomonas vaginalis calcineurin B subunit, putative 0.0152 0.0407 0.1068
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0062 0.0051
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Echinococcus granulosus calbindin 32 0.0155 0.0414 0.0414
Onchocerca volvulus Cell death protein 3 homolog 0.0184 0.0506 0.0938
Schistosoma mansoni cathepsin C 0.0297 0.0859 0.0859
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Entamoeba histolytica hypothetical protein 0.0044 0.0066 0.015
Entamoeba histolytica calmodulin, putative 0.0152 0.0407 0.1068
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Echinococcus multilocularis calumenin 0.0155 0.0414 0.0414
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0719 0.2182 0.2182
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0062 0.0139
Trichomonas vaginalis peptide N-glycanase, putative 0.0364 0.1069 0.2853
Leishmania major hypothetical protein, conserved 0.0152 0.0407 0.0735
Brugia malayi Cytochrome P450 family protein 0.006 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.007 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0119 0.0302 0.0302
Leishmania major cathepsin L-like protease 0.1317 0.4055 0.7507
Onchocerca volvulus 0.003 0.0024 0.0045
Mycobacterium tuberculosis Conserved protein 0.0036 0.0043 0.0018
Brugia malayi cathepsin F-like cysteine proteinase 0.037 0.1089 0.1089
Echinococcus multilocularis glycogen phosphorylase 0.0114 0.0287 0.0287
Trichomonas vaginalis calcineurin B subunit, putative 0.0155 0.0414 0.1089
Trypanosoma cruzi cysteine peptidase, putative 0.037 0.1089 0.1079
Echinococcus multilocularis EF hand domain containing family member A2 0.0155 0.0414 0.0414
Trypanosoma cruzi cysteine peptidase, putative 0.1317 0.4055 0.4048
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0131 0.034 0.0889
Brugia malayi Histone deacetylase family protein 0.0102 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Brugia malayi fibroinase precursor 0.0297 0.0859 0.0859
Mycobacterium tuberculosis Conserved protein 0.0364 0.1069 0.2214
Onchocerca volvulus Peroxidase homolog 0.0212 0.0592 0.1097
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0361 0.1059 0.105
Echinococcus multilocularis acylamino acid releasing enzyme 0.0221 0.0623 0.0623
Onchocerca volvulus 0.1617 0.4997 0.9257
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0335 0.0335
Entamoeba histolytica prolyl oligopeptidase family protein 0.0221 0.0623 0.1651
Trypanosoma brucei prolyl endopeptidase 0.1745 0.5398 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0043 0.0043
Leishmania major proteasome beta 5 subunit, putative 0.0091 0.0216 0.0381
Onchocerca volvulus 0.0119 0.0302 0.0559
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3214 1 1
Mycobacterium ulcerans hypothetical protein 0.0364 0.1069 0.4808
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0066 0.0066
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0115 0.029 0.029
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0719 0.2182 0.2182
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0043 0.0018
Schistosoma mansoni peroxidasin 0.0212 0.0592 0.0592
Toxoplasma gondii EF hand domain-containing protein 0.0152 0.0407 0.0735
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0152 0.0407 0.0396
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1209 0.3719 0.3719
Brugia malayi hypothetical protein 0.0263 0.0755 0.0755
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0286 0.0826 0.2198
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0286 0.0826 0.1513
Echinococcus multilocularis programmed cell death protein 0.0156 0.0418 0.0418
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Plasmodium falciparum cysteine proteinase falcipain 1 0.0667 0.2018 0.5415
Plasmodium vivax aspartyl protease, putative 0.0042 0.006 0.0134
Trypanosoma brucei caltractin, putative 0.0156 0.0418 0.0756
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0062 0.0138
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0297 0.0859 0.0859
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0119 0.0202
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.036 0.1058 0.1944
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0044 0.0067 0.0153
Echinococcus multilocularis apoptotic protease activating factor 1 0.0141 0.037 0.037
Echinococcus multilocularis caspase 3 0.0071 0.0153 0.0153
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0258 0.0739 0.0739
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0095 0.0226 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Schistosoma mansoni calpain-7 (C02 family) 0.0974 0.2983 0.2983
Loa Loa (eye worm) hypothetical protein 0.0091 0.0214 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0221 0.0623 0.1651
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Schistosoma mansoni chromatin regulatory protein sir2 0.0131 0.034 0.034
Brugia malayi Cathepsin L-like cysteine proteinase 0.0839 0.2559 0.2559
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0043 0.0088
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0044 0.0066 0.0066
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2741 0.8517 0.8517
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.015
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0135 0.0351 0.0351
Echinococcus granulosus histone deacetylase 8 0.0044 0.0067 0.0067
Schistosoma mansoni mitochondrial solute carrier 0.0152 0.0407 0.0407
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0786 0.2392 0.2392
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0066 0.0066
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.036 0.1058 0.1048
Trichomonas vaginalis calcium binding proteins, putative 0.0152 0.0407 0.1068
Trypanosoma brucei calpain-like protein, putative 0.0971 0.2972 0.5498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Brugia malayi beta-lactamase family protein 0.0036 0.0043 0.0043
Loa Loa (eye worm) transcriptional regulator 0.0131 0.034 0.034
Schistosoma mansoni calmodulin related calcium binding protein 0.0152 0.0407 0.0407
Echinococcus granulosus peroxidasin 0.0212 0.0592 0.0592
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0149 0.0149
Trypanosoma brucei Component of motile flagella 41 0.0152 0.0407 0.0735
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0042 0.006 0.0134
Mycobacterium ulcerans hypothetical protein 0.0119 0.0302 0.1239
Leishmania major silent information regulator 2, putative 0.0131 0.034 0.0612
Plasmodium falciparum histone deacetylase 1 0.0091 0.0214 0.0548
Plasmodium vivax plasmepsin V, putative 0.0042 0.006 0.0134
Brugia malayi proteasome subunit beta type 2 0.0044 0.0067 0.0067
Giardia lamblia Cathepsin L precursor 0.0297 0.0859 0.2309
Loa Loa (eye worm) hypothetical protein 0.0152 0.0407 0.0407
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Entamoeba histolytica grainin, putative 0.0155 0.0414 0.1089
Trypanosoma cruzi conserved protein 0.0286 0.0826 0.0816
Schistosoma mansoni gamma-secretase subunit aph-1 0.0258 0.0739 0.0739
Loa Loa (eye worm) hypothetical protein 0.0036 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.0859 0.2288
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0667 0.2018 0.2018
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0035 0.0066
Brugia malayi Histone deacetylase 1 0.0091 0.0214 0.0214
Trypanosoma brucei Calpain-like protein 1.2 0.0286 0.0826 0.1513
Brugia malayi Cathepsin L-like precursor 0.1209 0.3719 0.3719
Loa Loa (eye worm) glycogen phosphorylase 0.0114 0.0287 0.0287
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.006 0.0134
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0062 0.0062
Trichomonas vaginalis calpain, putative 0.0286 0.0826 0.2198
Plasmodium falciparum metacaspase-like protein 0.0044 0.0066 0.0149
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0119 0.0302 0.0302
Plasmodium vivax vivapain-3 0.0667 0.2018 0.5415
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0066 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.0859 0.2288
Giardia lamblia Cathepsin B precursor 0.0297 0.0859 0.2309
Trypanosoma cruzi histone deacetylase, putative 0.0102 0.0249 0.0239
Leishmania major histone deacetylase, putative 0.0102 0.0249 0.0442
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0152 0.0407 0.1068
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Echinococcus granulosus EF hand domain containing family member A2 0.0155 0.0414 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Trypanosoma brucei antigen, putative 0.0971 0.2972 0.5498
Loa Loa (eye worm) hypothetical protein 0.1209 0.3719 0.3719
Onchocerca volvulus Histone deacetylase 10 homolog 0.0044 0.0067 0.0123
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0043 0.0088
Brugia malayi Trypsin-like protease protein 5 0.0119 0.0302 0.0302
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0067 0.0067
Loa Loa (eye worm) beta-lactamase 0.0036 0.0043 0.0043
Trichomonas vaginalis calmodulin, putative 0.0152 0.0407 0.1068
Loa Loa (eye worm) hypothetical protein 0.0839 0.2559 0.2559
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0071 0.0152 0.0152
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0034 0.0035 0.0035
Brugia malayi Cathepsin L-like precursor 0.1209 0.3719 0.3719
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Onchocerca volvulus 0.0762 0.2315 0.429
Trypanosoma brucei Calpain-like protein CALP1.3 0.0286 0.0826 0.1513
Loa Loa (eye worm) hypothetical protein 0.0036 0.0043 0.0043
Brugia malayi histone deacetylase 11 0.0044 0.0067 0.0067
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2741 0.8517 0.8517
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0286 0.0826 0.0816
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0048 0.0079 0.0079
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0149 0.0149
Schistosoma mansoni calmodulin 0.0152 0.0407 0.0407
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0214 0.0548
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0043 0.0018
Echinococcus multilocularis histone deacetylase 6 0.0102 0.0249 0.0249
Trypanosoma cruzi calmodulin, putative 0.0152 0.0407 0.0396
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1745 0.5398 1
Entamoeba histolytica hypothetical protein, conserved 0.0155 0.0414 0.1089
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.006 0.0134
Trichomonas vaginalis calmodulin, putative 0.0152 0.0407 0.1068
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Toxoplasma gondii centrin 0.0152 0.0407 0.0735
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0062 0.0051
Brugia malayi calpain 5 0.0286 0.0826 0.0826
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0066 0.0055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.5498
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0084 0.0198
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Echinococcus multilocularis Dipeptidyl peptidase 9 0.036 0.1058 0.1058
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0002 0.0002
Onchocerca volvulus Cathepsin L homolog 0.1209 0.3719 0.6889
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0034 0.0035 0.0035
Trichomonas vaginalis centrin, putative 0.0152 0.0407 0.1068
Brugia malayi transcriptional regulator, Sir2 family protein 0.0034 0.0035 0.0035
Echinococcus multilocularis tissue type plasminogen activator 0.0047 0.0076 0.0076
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0043 0.0039
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1745 0.5398 0.5398
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0071 0.0152 0.0152
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Brugia malayi beta-lactamase family protein 0.0036 0.0043 0.0043
Trypanosoma cruzi histone deacetylase, putative 0.0102 0.0249 0.0239
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.036 0.1058 0.1048
Leishmania major histone deacetylase, putative 0.0091 0.0214 0.0377
Entamoeba histolytica cysteine protease, putative 0.0297 0.0859 0.2288
Loa Loa (eye worm) hypothetical protein 0.037 0.1089 0.1089
Echinococcus multilocularis cpg binding protein 0.0032 0.0029 0.0029
Brugia malayi regulator of G-protein signaling rgs-7 0.0044 0.0066 0.0066
Echinococcus multilocularis cathepsin L 0.0297 0.0859 0.0859
Leishmania major calmodulin, putative 0.0152 0.0407 0.0735
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0044 0.0066 0.0066
Leishmania major calpain family cysteine protease-like protein 0.0286 0.0826 0.1513
Echinococcus granulosus Mastin 0.0119 0.0302 0.0302
Echinococcus granulosus cathepsin L cysteine proteinase 0.1209 0.3719 0.3719
Entamoeba histolytica cysteine proteinase 2 0.0667 0.2018 0.5415
Loa Loa (eye worm) cathepsin B 0.1199 0.3686 0.3686
Brugia malayi Papain family cysteine protease containing protein 0.0297 0.0859 0.0859
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0066 0.0066
Echinococcus granulosus dnaJ subfamily B 0.043 0.1275 0.1275
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0055
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Trypanosoma brucei metacaspase 0.0044 0.0066 0.0103
Plasmodium vivax histone deacetylase 1, putative 0.0091 0.0214 0.0548
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0297 0.0859 0.2288
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0297 0.0859 0.0859
Onchocerca volvulus 0.0212 0.0592 0.1097
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0131 0.034 0.034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Brugia malayi calpain family protein 1 0.2589 0.804 0.804
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Loa Loa (eye worm) hypothetical protein 0.0184 0.0506 0.0506
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.0816
Loa Loa (eye worm) hypothetical protein 0.0058 0.0112 0.0112
Plasmodium falciparum serine repeat antigen 8 0.0297 0.0859 0.2288
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0034 0.0035 0.0066
Plasmodium falciparum plasmepsin IX 0.0203 0.0564 0.1492
Echinococcus multilocularis Mastin 0.0119 0.0302 0.0302
Giardia lamblia Transglutaminase/protease, putative 0.0364 0.1069 0.2879
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0002 0.0002
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Brugia malayi hypothetical protein 0.0044 0.0066 0.0066
Brugia malayi carbohydrate phosphorylase 0.0114 0.0287 0.0287
Schistosoma mansoni Mername-AA248 (C02 family) 0.0971 0.2972 0.2972
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0066 0.0066
Toxoplasma gondii proteasome subunit beta type, putative 0.0091 0.0216 0.0381
Leishmania major sir2-family protein-like protein 0.0034 0.0035 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.0859 0.2288
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0138 0.036 0.0943
Schistosoma mansoni peroxidasin 0.0212 0.0592 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0149
Loa Loa (eye worm) papain family cysteine protease containing protein 0.037 0.1089 0.1089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0149 0.0149
Leishmania major cytochrome p450-like protein 0.0036 0.0043 0.0059
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0043 0.0043
Plasmodium vivax proteasome subunit beta type-2, putative 0.0044 0.0067 0.0153
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0286 0.0826 0.2198
Brugia malayi Cathepsin L-like precursor 0.1209 0.3719 0.3719
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0214 0.0548
Toxoplasma gondii peptidase family M13 protein 0.0095 0.0226 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0062 0.0138
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Echinococcus multilocularis EF hand domain containing family member A2 0.0152 0.0407 0.0407
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0667 0.2018 0.2018
Brugia malayi Papain family cysteine protease containing protein 0.0667 0.2018 0.2018
Entamoeba histolytica cysteine protease, putative 0.0297 0.0859 0.2288
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0034 0.0035 0.0024
Echinococcus granulosus EF HAND 1 calcium binding site 0.0152 0.0407 0.0407
Toxoplasma gondii preprocathepsin c precursor, putative 0.0297 0.0859 0.1575
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0719 0.2182 0.2182
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0286 0.0826 0.0816
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0297 0.0859 0.2288
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0091 0.0216 0.0381
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.037 0.1089 0.1089
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Echinococcus multilocularis calmodulin 0.0152 0.0407 0.0407
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.5498
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0104 0.0104
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0297 0.0859 0.0859
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Mycobacterium ulcerans hypothetical protein 0.0364 0.1069 0.4808
Loa Loa (eye worm) hypothetical protein 0.0042 0.006 0.006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0145 0.0384 0.1007
Echinococcus granulosus cathepsin L cysteine protease 0.0667 0.2018 0.2018
Loa Loa (eye worm) blistered cuticle protein 3 0.0212 0.0592 0.0592
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0351 0.1469
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1209 0.3719 0.3719
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1317 0.4055 0.7507
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0062 0.0062
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0155 0.0414 0.0414
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Schistosoma mansoni hypothetical protein 0.0152 0.0407 0.0407
Schistosoma mansoni neuronal calcium sensor 0.0152 0.0407 0.0407
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0043 0.0043
Giardia lamblia Histone deacetylase 0.0091 0.0214 0.0553
Echinococcus granulosus histone deacetylase 6 0.0108 0.0269 0.0269
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0592 0.0592
Onchocerca volvulus 0.0042 0.006 0.0112
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0066 0.0066
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0067 0.0067
Brugia malayi cathepsin L-like cysteine proteinase 0.0297 0.0859 0.0859
Echinococcus multilocularis regulator of G protein signaling 0.0044 0.0066 0.0066
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.072 0.2185 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Echinococcus granulosus histone deacetylase 7 0.0102 0.0249 0.0249
Leishmania major cathepsin L-like protease 0.1209 0.3719 0.6883
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0043 0.0088
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Plasmodium falciparum plasmepsin I 0.0042 0.006 0.0134
Onchocerca volvulus 0.003 0.0024 0.0045
Echinococcus granulosus expressed protein 0.0851 0.2596 0.2596
Echinococcus multilocularis cathepsin L cysteine protease 0.1209 0.3719 0.3719
Onchocerca volvulus 0.0189 0.0521 0.0966
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Loa Loa (eye worm) hypothetical protein 0.0297 0.0859 0.0859
Trypanosoma brucei Metacaspase-4 0.0044 0.0066 0.0103
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1209 0.3719 1
Plasmodium vivax vivapain-1 0.0667 0.2018 0.5415
Plasmodium falciparum serine repeat antigen 1 0.0297 0.0859 0.2288
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0228 0.0228
Leishmania major protein kinase, putative 0.0152 0.0407 0.0735
Echinococcus multilocularis endothelin converting enzyme 1 0.0095 0.0226 0.0226
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0297 0.0859 0.2288
Toxoplasma gondii cathepsin CPC1 0.0297 0.0859 0.1575
Onchocerca volvulus 0.0119 0.0302 0.0559
Brugia malayi histone deacetylase 3 (HD3) 0.0091 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0212 0.0592 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0297 0.0859 0.2288
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0152 0.0407 0.0407
Trypanosoma brucei mitochondrial calcium uptake 1 0.0152 0.0407 0.0735
Echinococcus multilocularis calpain 5 0.0971 0.2972 0.2972
Toxoplasma gondii cathepsin B 0.1199 0.3686 0.6823
Echinococcus granulosus glycogen phosphorylase 0.0114 0.0287 0.0287
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0066 0.0066
Entamoeba histolytica prolyl oligopeptidase family protein 0.0221 0.0623 0.1651
Brugia malayi Cathepsin L-like precursor 0.1209 0.3719 0.3719
Leishmania major proteasome beta 2 subunit, putative 0.0044 0.0067 0.0105
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0351 0.1469
Plasmodium falciparum serine repeat antigen 4 0.0297 0.0859 0.2288
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0189 0.0521 0.0521
Mycobacterium ulcerans proteasome PrcB 0.0091 0.0216 0.084
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0034 0.0035 0.0045
Leishmania major centrin, putative 0.0152 0.0407 0.0735
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Trypanosoma cruzi cysteine proteinase, putative 0.0667 0.2018 0.201
Toxoplasma gondii hypothetical protein 0.003 0.0024 0.0025
Echinococcus multilocularis enteropeptidase 0.0119 0.0302 0.0302
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Schistosoma mansoni histone deacetylase 1 2 3 0.0044 0.0067 0.0067
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0297 0.0859 0.0859
Brugia malayi Cathepsin L-like precursor 0.1209 0.3719 0.3719
Echinococcus multilocularis survival motor neuron protein 1 0.0263 0.0755 0.0755
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0152 0.0407 0.0407
Entamoeba histolytica glycogenphosphorylase, putative 0.0049 0.0084 0.0198
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3214 1 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0603 0.1819 0.1819
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0623 0.0613
Entamoeba histolytica cysteine proteinase 1, putative 0.0667 0.2018 0.5415
Plasmodium vivax unspecified product 0.0297 0.0859 0.2288
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.072 0.2185 1
Trichomonas vaginalis calmodulin-2, putative 0.0152 0.0407 0.1068
Brugia malayi Peptidase family M13 containing protein 0.0095 0.0226 0.0226
Brugia malayi PAN domain containing protein 0.003 0.0024 0.0024
Giardia lamblia Proteasome subunit beta type 1 0.0071 0.0152 0.0384
Loa Loa (eye worm) hypothetical protein 0.0119 0.0302 0.0302
Trichomonas vaginalis calpain, putative 0.0286 0.0826 0.2198
Echinococcus granulosus cathepsin b 0.3214 1 1
Schistosoma mansoni histone deacetylase hda2 0.0044 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0667 0.2018 0.3727
Loa Loa (eye worm) hypothetical protein 0.0111 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0047 0.0076 0.0076
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0297 0.0859 0.2288
Entamoeba histolytica cysteine protease, putative 0.0667 0.2018 0.5415
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0297 0.0859 0.2288
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.072 0.2185 0.4036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Echinococcus multilocularis cathepsin L 0.0667 0.2018 0.2018
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0286 0.0826 0.2198
Giardia lamblia Cathepsin L precursor 0.0297 0.0859 0.2309
Giardia lamblia Cysteine protease 0.0297 0.0859 0.2309
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0043 0.0043
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0221 0.0623 0.1651
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0062 0.0095
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0042 0.006 0.006
Trypanosoma cruzi calmodulin, putative 0.0152 0.0407 0.0396
Brugia malayi aspartic protease BmAsp-1, identical 0.0042 0.006 0.006
Trypanosoma cruzi histone deacetylase, putative 0.0044 0.0067 0.0056
Toxoplasma gondii PAN domain-containing protein 0.003 0.0024 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1209 0.3719 1
Loa Loa (eye worm) hypothetical protein 0.2589 0.804 0.804
Echinococcus granulosus caspase 2 0.0184 0.0506 0.0506
Trypanosoma cruzi cysteine protease, putative 0.0667 0.2018 0.201
Loa Loa (eye worm) hypothetical protein 0.0036 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0297 0.0859 0.0859
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0149
Trypanosoma brucei histone deacetylase 3 0.0102 0.0249 0.0442
Schistosoma mansoni neprilysin-2 (M13 family) 0.0048 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.006 0.006
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0067 0.0153
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0024 0.0025
Leishmania major metacaspase, putative 0.0044 0.0066 0.0103
Toxoplasma gondii aspartyl protease 0.0042 0.006 0.0092
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0152 0.0407 0.0396
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0066 0.0066
Toxoplasma gondii microneme protein, putative 0.003 0.0024 0.0025
Toxoplasma gondii histone deacetylase HDAC1 0.0102 0.0249 0.0442
Schistosoma mansoni cercarial elastase (S01 family) 0.0119 0.0302 0.0302
Leishmania major hypothetical protein, conserved 0.0286 0.0826 0.1513
Onchocerca volvulus 0.003 0.0024 0.0045
Echinococcus multilocularis gamma secretase subunit aph 1 0.0258 0.0739 0.0739
Giardia lamblia Transcriptional regulator, Sir2 family 0.0034 0.0035 0.0066
Brugia malayi hypothetical protein 0.017 0.0463 0.0463
Loa Loa (eye worm) histone deacetylase 7A 0.0102 0.0249 0.0249
Schistosoma mansoni reticulocalbin 0.0155 0.0414 0.0414
Echinococcus multilocularis Regulator of G protein signaling 20 0.0044 0.0066 0.0066
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0071 0.0152 0.0381
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0043 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0043 0.0043
Entamoeba histolytica cysteine protease, putative 0.0297 0.0859 0.2288
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0971 0.2972 0.2965
Leishmania major histone deacetylase, putative 0.0091 0.0214 0.0377
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0071 0.0152 0.0262
Mycobacterium ulcerans hypothetical protein 0.0036 0.0043 0.0039
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0228 0.0228
Giardia lamblia Encystation-specific protease 0.0297 0.0859 0.2309
Leishmania major cathepsin L-like protease 0.1209 0.3719 0.6883
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0044 0.0066 0.015
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0214 0.0548
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0034 0.0035 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0667 0.2018 0.5415
Toxoplasma gondii PAN domain-containing protein 0.003 0.0024 0.0025
Echinococcus granulosus cysteine protease 0.0667 0.2018 0.2018
Leishmania major kinesin, putative 0.0685 0.2076 0.3834
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0044 0.0067 0.0057
Echinococcus granulosus prolyl endopeptidase 0.1745 0.5398 0.5398
Trichomonas vaginalis calmodulin, putative 0.0156 0.0418 0.1099
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0043 0.0043
Brugia malayi transcriptional regulator, Sir2 family protein 0.0034 0.0035 0.0035
Echinococcus multilocularis glycogen phosphorylase 0.0114 0.0287 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.0826 0.2198
Echinococcus multilocularis caspase 0.0115 0.029 0.029
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0214 0.0548
Schistosoma mansoni survival motor neuron protein 0.0054 0.0098 0.0098
Trypanosoma cruzi kinesin, putative 0.0685 0.2076 0.2068
Entamoeba histolytica cysteine proteinase, putative 0.0667 0.2018 0.5415
Brugia malayi Cathepsin L-like precursor 0.1209 0.3719 0.3719
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0091 0.0216 0.0558
Onchocerca volvulus 0.0839 0.2559 0.4742
Toxoplasma gondii histone deacetylase HDAC4 0.0044 0.0067 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0149
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0066 0.0066
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0055
Brugia malayi Cytochrome P450 family protein 0.0036 0.0043 0.0043
Leishmania major centrin, putative 0.0152 0.0407 0.0735
Plasmodium vivax histone deacetylase, putative 0.0044 0.0067 0.0151
Loa Loa (eye worm) hypothetical protein 0.3214 1 1
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0131 0.034 0.0612
Schistosoma mansoni calpain-2 (C02 family) 0.0286 0.0826 0.0826
Loa Loa (eye worm) hypothetical protein 0.0036 0.0043 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0286 0.0826 0.1513
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0062 0.0138
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0592 0.0592
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.072 0.2185 0.2176
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0062 0.0051
Echinococcus multilocularis histone deacetylase 0.0102 0.0249 0.0249
Schistosoma mansoni cathepsin B (C01 family) 0.0297 0.0859 0.0859
Loa Loa (eye worm) hypothetical protein 0.0221 0.0623 0.0623
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0062 0.0138
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0286 0.0826 0.0816
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0071 0.0152 0.0152
Trypanosoma brucei Calpain-like protein 1.1 0.0286 0.0826 0.1513
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0062 0.0138
Entamoeba histolytica calcium binding family protein 0.0152 0.0407 0.1068
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0145 0.0384 0.1016
Brugia malayi hypothetical protein 0.0119 0.0302 0.0302
Echinococcus granulosus Regulator of G protein signaling 20 0.0044 0.0066 0.0066
Toxoplasma gondii microneme protein MIC17B 0.003 0.0024 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1209 0.3719 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0404 0.1195 0.1186
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Toxoplasma gondii centrin, putative 0.0152 0.0407 0.0735
Leishmania major programmed cell death 6 protein-like protein 0.0152 0.0407 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0667 0.2018 0.5415
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0066 0.0066
Giardia lamblia Hypothetical protein 0.0297 0.0859 0.2309
Entamoeba histolytica histone deacetylase, putative 0.0091 0.0214 0.0548
Onchocerca volvulus 0.1209 0.3719 0.6889
Trichomonas vaginalis calmodulin, putative 0.0152 0.0407 0.1068
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0297 0.0859 0.2288
Giardia lamblia Hypothetical protein 0.0364 0.1069 0.2879
Loa Loa (eye worm) histone deacetylase 0.0102 0.0249 0.0249
Echinococcus multilocularis glycoprotein Antigen 5 0.0119 0.0302 0.0302
Giardia lamblia Cathepsin L-like protease 0.0297 0.0859 0.2309
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0119 0.0302 0.0302
Echinococcus granulosus cathepsin L 0.0297 0.0859 0.0859
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1209 0.3719 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.0297 0.0859 0.0859
Loa Loa (eye worm) PXA domain-containing protein 0.0044 0.0066 0.0066
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0043 0.0018

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0586 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.2908 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 0.651 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.