Detailed information for compound 160028

Basic information

Technical information
  • TDR Targets ID: 160028
  • Name: 2-acetamido-N-benzyl-2-pyridin-2-ylacetamide
  • MW: 283.325 | Formula: C16H17N3O2
  • H donors: 2 H acceptors: 3 LogP: 1.04 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)NC(c1ccccn1)C(=O)NCc1ccccc1
  • InChi: 1S/C16H17N3O2/c1-12(20)19-15(14-9-5-6-10-17-14)16(21)18-11-13-7-3-2-4-8-13/h2-10,15H,11H2,1H3,(H,18,21)(H,19,20)
  • InChiKey: UCPDMCGOMZCDGT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-acetamido-N-benzyl-2-(2-pyridyl)acetamide
  • 2-acetamido-N-(phenylmethyl)-2-pyridin-2-yl-ethanamide
  • 2-acetamido-N-(phenylmethyl)-2-pyridin-2-ylacetamide
  • 2-acetamido-N-(phenylmethyl)-2-(2-pyridyl)acetamide
  • 2-acetamido-N-(benzyl)-2-(2-pyridyl)acetamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major hypothetical protein, conserved 0.0234 0.0767 0.1419
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1089 0.3809 1
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0629 0.2173 0.2173
Onchocerca volvulus 0.0095 0.0273 0.0506
Echinococcus multilocularis calpain A 0.2255 0.7951 0.7951
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0021 0.0014 0.0036
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Brugia malayi Histone deacetylase 1 0.0087 0.0248 0.0248
Trypanosoma cruzi centrin, putative 0.0133 0.0411 0.0411
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0266 0.0882 0.2315
Toxoplasma gondii centrin 0.013 0.0398 0.0737
Entamoeba histolytica grainin, putative 0.0132 0.0407 0.1068
Toxoplasma gondii microneme protein MIC17C 0.003 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0187 0.0601 0.1577
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0796 0.2765 0.2765
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0132 0.0132
Mycobacterium tuberculosis Conserved protein 0.0035 0.0062 0.0131
Leishmania major protein kinase, putative 0.013 0.0398 0.0737
Trichomonas vaginalis calmodulin, putative 0.0132 0.0407 0.1068
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0248 0.0651
Echinococcus granulosus enteropeptidase 0.0081 0.0225 0.0225
Leishmania major cathepsin L-like protease 0.1193 0.4179 0.7729
Brugia malayi Trypsin family protein 0.0081 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.1539 0.5406 0.5406
Brugia malayi hypothetical protein 0.0169 0.054 0.054
Onchocerca volvulus 0.1089 0.3809 0.7046
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0014
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.054 0.054
Trichomonas vaginalis calcineurin B subunit, putative 0.0132 0.0407 0.1068
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.013 0.0398 0.0398
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0006 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1059 0.3702 0.9718
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0266 0.0882 0.2315
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.013 0.0398 0.0398
Schistosoma mansoni hypothetical protein 0.0046 0.0101 0.0101
Loa Loa (eye worm) blistered cuticle protein 3 0.0169 0.054 0.054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1059 0.3702 0.3702
Leishmania major programmed cell death 6 protein-like protein 0.013 0.0398 0.0737
Trypanosoma cruzi oligopeptidase b 0.0629 0.2173 0.2173
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.5115
Echinococcus multilocularis cysteine protease 0.1089 0.3809 0.3809
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Echinococcus multilocularis cathepsin b 0.2831 1 1
Brugia malayi peptidase family M13 containing protein 0.0023 0.0018 0.0018
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0087 0.0161
Brugia malayi Cell death protein 3 precursor 0.0095 0.0273 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0882 0.2315
Leishmania major cathepsin L-like protease 0.1193 0.4179 0.7729
Trypanosoma cruzi prolyl endopeptidase 0.1539 0.5406 0.5406
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0091 0.0168
Plasmodium vivax histone deacetylase 2, putative 0.0098 0.0286 0.0752
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Echinococcus granulosus cathepsin l cysteine peptidase 0.1089 0.3809 0.3809
Echinococcus multilocularis histone deacetylase 0.0098 0.0286 0.0286
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0101 0.0101
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0187 0.0601 0.0601
Loa Loa (eye worm) hypothetical protein 0.0069 0.0182 0.0182
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0266 0.0882 0.2315
Leishmania major histone deacetylase, putative 0.0098 0.0286 0.053
Plasmodium falciparum histone deacetylase 1 0.0087 0.0248 0.0651
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0266 0.0882 0.0882
Echinococcus multilocularis prolyl endopeptidase 0.1539 0.5406 0.5406
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Trypanosoma brucei hypothetical protein 0.0234 0.0767 0.1419
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0062 0.0285
Trypanosoma brucei centrin, putative 0.013 0.0398 0.0737
Echinococcus granulosus Dipeptidyl peptidase 9 0.0278 0.0926 0.0926
Echinococcus multilocularis Glycosyl transferase, family 35 0.0112 0.0336 0.0336
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0234 0.0767 0.2015
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.003 0.0044 0.0044
Schistosoma mansoni centrin-related 0.013 0.0398 0.0398
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.013 0.0398 0.0737
Leishmania major histone deacetylase, putative 0.0087 0.0248 0.0459
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0401 0.1846
Echinococcus multilocularis calpain 5 0.0796 0.2765 0.2765
Schistosoma mansoni coup transcription factor 0.0022 0.0015 0.0015
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0028 0.0074
Giardia lamblia Cathepsin B precursor 0.1059 0.3702 1
Echinococcus granulosus histone deacetylase 0.0098 0.0286 0.0286
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0629 0.2173 0.4019
Schistosoma mansoni reticulocalbin 0.013 0.0398 0.0398
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Leishmania major sir2-family protein-like protein 0.007 0.0187 0.0346
Trichomonas vaginalis calcineurin B subunit, putative 0.013 0.0398 0.1046
Loa Loa (eye worm) hypothetical protein 0.0095 0.0273 0.0273
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0286 0.0286
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.054 0.054
Loa Loa (eye worm) hypothetical protein 0.0187 0.0601 0.0601
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0015 0.0015
Schistosoma mansoni cathepsin C 0.0266 0.0882 0.0882
Echinococcus granulosus histone deacetylase 6 0.0104 0.0308 0.0308
Schistosoma mansoni cathepsin F (C01 family) 0.0756 0.2623 0.2623
Trypanosoma brucei calpain-like protein, putative 0.0796 0.2765 0.5115
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0629 0.2173 0.4019
Entamoeba histolytica protein kinase, putative 0.0562 0.1935 0.5081
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0081 0.0225 0.0225
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.0601 0.0601
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0062 0.0131
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0334 0.1124 0.1124
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Schistosoma mansoni reticulocalbin 0.0132 0.0407 0.0407
Mycobacterium ulcerans beta-lactamase 0.0035 0.0062 0.0285
Onchocerca volvulus Chorion peroxidase homolog 0.0169 0.054 0.0998
Echinococcus multilocularis transmembrane protease serine 3 0.0081 0.0225 0.0225
Schistosoma mansoni calpain-2 (C02 family) 0.0234 0.0767 0.0767
Echinococcus granulosus programmed cell death protein 0.0133 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0042 0.0087 0.0087
Brugia malayi prolyl oligopeptidase family protein 0.0278 0.0926 0.0926
Plasmodium falciparum centrin-1 0.013 0.0398 0.1046
Giardia lamblia Cysteine protease 0.0266 0.0882 0.2382
Brugia malayi Papain family cysteine protease containing protein 0.06 0.2069 0.2069
Loa Loa (eye worm) hypothetical protein 0.0042 0.0088 0.0088
Onchocerca volvulus 0.1089 0.3809 0.7046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0267 0.0267
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0248 0.0651
Schistosoma mansoni calpain C (C02 family) 0.0796 0.2765 0.2765
Loa Loa (eye worm) programmed cell death protein 6 0.0132 0.0407 0.0407
Entamoeba histolytica hypothetical protein 0.0042 0.0088 0.0231
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0088 0.0231
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0248 0.0651
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0062 0.0062
Echinococcus multilocularis cathepsin b 0.2831 1 1
Giardia lamblia Cathepsin L precursor 0.0266 0.0882 0.2382
Entamoeba histolytica hypothetical protein, conserved 0.007 0.0187 0.0491
Toxoplasma gondii prolyl endopeptidase 0.1539 0.5406 1
Echinococcus granulosus histone deacetylase 7 0.0098 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0188
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0088 0.0088
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Toxoplasma gondii histone deacetylase SIR2 0.007 0.0187 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0234 0.0767 0.2015
Loa Loa (eye worm) hypothetical protein 0.0756 0.2623 0.2623
Brugia malayi cathepsin Z-like cysteine proteinase 0.0266 0.0882 0.0882
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0015 0.0015
Leishmania major hypothetical protein, unknown function 0.0234 0.0767 0.1419
Echinococcus granulosus calpain A 0.2255 0.7951 0.7951
Brugia malayi cathepsin L precursor 0.0266 0.0882 0.0882
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0015 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.0266 0.0882 0.0882
Onchocerca volvulus Prolyl endopeptidase homolog 0.1539 0.5406 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.0256 0.0256
Leishmania major calmodulin-like protein 0.013 0.0398 0.0737
Mycobacterium ulcerans lipase LipD 0.0035 0.0062 0.0285
Brugia malayi Pepsin A precursor 0.003 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0062 0.0062
Echinococcus multilocularis enteropeptidase 0.0081 0.0225 0.0225
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0088 0.0088
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0796 0.2765 0.2765
Onchocerca volvulus 0.0081 0.0225 0.0416
Echinococcus multilocularis EF hand domain containing family member A2 0.013 0.0398 0.0398
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0266 0.0882 0.0882
Trypanosoma brucei Calpain-like protein CALP1.3 0.0234 0.0767 0.1419
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0254 0.084 0.084
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.018 0.0576 0.0576
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0088 0.0088
Onchocerca volvulus 0.0021 0.0014 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0062 0.0163
Brugia malayi Cytochrome P450 family protein 0.0035 0.0062 0.0062
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0088 0.0088
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0143 0.0143
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.009 0.0256 0.0672
Trichomonas vaginalis calmodulin, putative 0.013 0.0398 0.1046
Echinococcus multilocularis glycogen phosphorylase 0.0112 0.0336 0.0336
Trichomonas vaginalis calcium binding protein, putative 0.0133 0.0411 0.1079
Echinococcus granulosus cathepsin l1 0.0756 0.2623 0.2623
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0014 0.0014
Trypanosoma cruzi centrin-3 0.0133 0.0411 0.0411
Echinococcus granulosus Glycosyl transferase family 35 0.0112 0.0336 0.0336
Echinococcus granulosus cysteine protease 0.06 0.2069 0.2069
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Echinococcus multilocularis hypothetical protein 0.0796 0.2765 0.2765
Loa Loa (eye worm) calmodulin-like protein 0.013 0.0398 0.0398
Leishmania major centrin, putative,caltractin, putative 0.013 0.0398 0.0737
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0266 0.0882 0.2315
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0187 0.0601 0.1111
Giardia lamblia Cathepsin B precursor 0.0266 0.0882 0.2382
Onchocerca volvulus Peroxidase homolog 0.0169 0.054 0.0998
Plasmodium falciparum plasmepsin I 0.003 0.0044 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0266 0.0882 0.2315
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Trichomonas vaginalis glycogen phosphorylase, putative 0.0112 0.0336 0.0882
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0088 0.0088
Trypanosoma brucei histone deacetylase 1 0.0087 0.0248 0.0459
Onchocerca volvulus Cathepsin L homolog 0.1089 0.3809 0.7046
Brugia malayi fibroinase precursor 0.0266 0.0882 0.0882
Echinococcus multilocularis cysteine protease 0.1089 0.3809 0.3809
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0234 0.0767 0.2015
Mycobacterium ulcerans zinc metalloprotease 0.0093 0.0269 0.1237
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0266 0.0882 0.2315
Loa Loa (eye worm) histone deacetylase 7A 0.0098 0.0286 0.0286
Brugia malayi histone deacetylase 11 0.0042 0.0087 0.0087
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0042 0.0088 0.0088
Schistosoma mansoni Mername-AA248 (C02 family) 0.0796 0.2765 0.2765
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.003 0.0044 0.0044
Echinococcus multilocularis gamma secretase subunit aph 1 0.0254 0.084 0.084
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2831 1 1
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0132 0.0407 0.0407
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0028 0.0074
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0028 0.0076
Leishmania major calmodulin-like protein 0.013 0.0398 0.0737
Brugia malayi Cytochrome P450 family protein 0.0058 0.0143 0.0143
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1089 0.3809 1
Mycobacterium tuberculosis Transcriptional regulatory protein 0.007 0.0187 0.0394
Entamoeba histolytica cysteine protease, putative 0.0266 0.0882 0.2315
Brugia malayi prolyl oligopeptidase family protein 0.1539 0.5406 0.5406
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Onchocerca volvulus 0.003 0.0044 0.008
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0248 0.0651
Echinococcus granulosus centrin 2 0.013 0.0398 0.0398
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0088 0.0231
Schistosoma mansoni cathepsin F (C01 family) 0.1089 0.3809 0.3809
Trypanosoma cruzi centrin, putative 0.0133 0.0411 0.0411
Brugia malayi Animal haem peroxidase family protein 0.0169 0.054 0.054
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0266 0.0882 0.2315
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Plasmodium falciparum plasmepsin II 0.003 0.0044 0.0114
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Loa Loa (eye worm) trypsin family protein 0.0081 0.0225 0.0225
Echinococcus multilocularis centrin 2 0.013 0.0398 0.0398
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0048 0.011 0.0231
Brugia malayi calpain 7 0.0796 0.2765 0.2765
Brugia malayi Blistered cuticle protein 3 0.0169 0.054 0.054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0267 0.0267
Toxoplasma gondii proteasome subunit beta type, putative 0.009 0.0256 0.0473
Schistosoma mansoni ap endonuclease 0.0019 0.0006 0.0006
Trypanosoma brucei cysteine peptidase C (CPC) 0.1059 0.3702 0.6847
Toxoplasma gondii preprocathepsin c precursor, putative 0.0266 0.0882 0.1631
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.0018 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0266 0.0882 0.2315
Toxoplasma gondii proteasome subunit beta type 1, putative 0.007 0.0185 0.0342
Schistosoma mansoni neprilysin 0.0024 0.0024 0.0024
Trichomonas vaginalis calpain, putative 0.0234 0.0767 0.2015
Trypanosoma cruzi cysteine peptidase, putative 0.1089 0.3809 0.3809
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0234 0.0767 0.0767
Echinococcus granulosus transmembrane protease serine 3 0.0081 0.0225 0.0225
Brugia malayi calcium-binding protein 0.013 0.0398 0.0398
Schistosoma mansoni chromatin regulatory protein sir2 0.0273 0.0908 0.0908
Schistosoma mansoni hypothetical protein 0.018 0.0576 0.0576
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0225
Giardia lamblia Histone deacetylase 0.0087 0.0248 0.067
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0015 0.0015
Schistosoma mansoni cathepsin B (C01 family) 0.0266 0.0882 0.0882
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Brugia malayi Kringle domain containing protein 0.0046 0.0101 0.0101
Giardia lamblia Hypothetical protein 0.0266 0.0882 0.2382
Trichomonas vaginalis calpain, putative 0.0234 0.0767 0.2015
Trichomonas vaginalis calcium binding protein, putative 0.013 0.0398 0.1046
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0088 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0015 0.0015
Schistosoma mansoni survival motor neuron protein 0.0053 0.0125 0.0125
Schistosoma mansoni calpain (C02 family) 0.0796 0.2765 0.2765
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0015 0.0015
Loa Loa (eye worm) sirtuin 4 0.007 0.0187 0.0187
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0091 0.0091
Entamoeba histolytica cysteine proteinase, putative 0.1089 0.3809 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0173 0.0173
Plasmodium vivax proteasome subunit beta type-5, putative 0.009 0.0256 0.0672
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0165 0.0525 0.0525
Loa Loa (eye worm) hypothetical protein 0.0069 0.0182 0.0182
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Echinococcus multilocularis microtubule associated protein 2 0.1492 0.5238 0.5238
Giardia lamblia Cysteine protease 0.0266 0.0882 0.2382
Toxoplasma gondii centrin, putative 0.013 0.0398 0.0737
Onchocerca volvulus 0.1089 0.3809 0.7046
Loa Loa (eye worm) hypothetical protein 0.013 0.0398 0.0398
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.2765
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0088 0.0088
Trypanosoma cruzi I/6 autoantigen, putative 0.013 0.0398 0.0398
Trichomonas vaginalis calcium binding protein, putative 0.013 0.0398 0.1046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0015 0.0015
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0234 0.0767 0.0767
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.007 0.0187 0.0346
Brugia malayi Proteasome A-type and B-type family protein 0.009 0.0256 0.0256
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0062 0.0163
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0248 0.0651
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0081 0.0225 0.0225
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0187 0.0601 0.0601
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Trichomonas vaginalis calmodulin, putative 0.013 0.0398 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0015 0.0015
Mycobacterium leprae Conserved hypothetical protein 0.0248 0.082 0.3776
Onchocerca volvulus 0.0035 0.0062 0.0115
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0015 0.0015
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0006 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Loa Loa (eye worm) hypothetical protein 0.0334 0.1124 0.1124
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0225
Trichomonas vaginalis glycogen phosphorylase, putative 0.0112 0.0336 0.0882
Giardia lamblia Cathepsin L precursor 0.0266 0.0882 0.2382
Brugia malayi Trypsin family protein 0.0081 0.0225 0.0225
Toxoplasma gondii microneme protein MIC4 0.003 0.0043 0.008
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0015 0.0015
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.009 0.0256 0.0256
Echinococcus multilocularis tumor protein p63 0.0373 0.1264 0.1264
Entamoeba histolytica calpain family cysteine protease, putative 0.0234 0.0767 0.2015
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0091 0.0238
Onchocerca volvulus 0.003 0.0043 0.008
Mycobacterium ulcerans hypothetical protein 0.0035 0.0062 0.0285
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0015 0.0015
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0273 0.0908 0.0908
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Toxoplasma gondii PAN domain-containing protein 0.003 0.0043 0.008
Onchocerca volvulus Deterin homolog 0.018 0.0576 0.1066
Loa Loa (eye worm) hypothetical protein 0.0055 0.0132 0.0132
Trypanosoma cruzi cruzipain precursor, putative 0.1193 0.4179 0.4179
Brugia malayi cathepsin L-like precursor 0.0756 0.2623 0.2623
Mycobacterium ulcerans hypothetical protein 0.0081 0.0225 0.1036
Trypanosoma brucei histone deacetylase 2 0.0042 0.0087 0.0161
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.4179 0.4179
Plasmodium vivax calpain, putative 0.0796 0.2765 0.726
Entamoeba histolytica hypothetical protein, conserved 0.0132 0.0407 0.1068
Entamoeba histolytica hypothetical protein 0.0042 0.0088 0.0231
Trypanosoma cruzi conserved protein 0.0234 0.0767 0.0767
Echinococcus granulosus flap endonuclease 1 0.0026 0.0028 0.0028
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0006 0.0017
Mycobacterium tuberculosis Long conserved protein 0.0248 0.082 0.1729
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0266 0.0882 0.2315
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0091 0.0238
Brugia malayi Cathepsin L-like precursor 0.0756 0.2623 0.2623
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Onchocerca volvulus 0.003 0.0043 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0756 0.2623 0.6885
Trypanosoma cruzi calmodulin, putative 0.013 0.0398 0.0398
Mycobacterium tuberculosis Conserved protein 0.0035 0.0062 0.0131
Plasmodium falciparum plasmepsin VIII, putative 0.003 0.0044 0.0114
Brugia malayi calpain family protein 1 0.2123 0.7482 0.7482
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1059 0.3702 0.6847
Onchocerca volvulus 0.0132 0.0407 0.0752
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0088 0.0088
Onchocerca volvulus 0.003 0.0044 0.008
Plasmodium vivax histone deacetylase 1, putative 0.0087 0.0248 0.0651
Onchocerca volvulus 0.003 0.0043 0.008
Brugia malayi EF hand family protein 0.013 0.0398 0.0398
Plasmodium vivax aspartyl protease, putative 0.003 0.0044 0.0114
Schistosoma mansoni chromatin regulatory protein sir2 0.007 0.0187 0.0187
Leishmania major calcineurin B subunit, putative 0.013 0.0398 0.0737
Trichomonas vaginalis calcium binding protein, putative 0.013 0.0398 0.1046
Schistosoma mansoni hypothetical protein 0.0095 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.003 0.0043 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0015 0.0015
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0514 0.1765 0.1765
Echinococcus multilocularis dnaJ subfamily B 0.0422 0.1437 0.1437
Brugia malayi prolyl oligopeptidase family protein 0.0187 0.0601 0.0601
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0088 0.0088
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.054 0.054
Schistosoma mansoni cathepsin D (A01 family) 0.0122 0.037 0.037
Loa Loa (eye worm) hypothetical protein 0.0042 0.0088 0.0088
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.013 0.0398 0.1046
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0266 0.0882 0.2315
Entamoeba histolytica cysteine protease, putative 0.1089 0.3809 1
Trypanosoma brucei I/6 autoantigen 0.013 0.0398 0.0737
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Plasmodium falciparum serine repeat antigen 8 0.0266 0.0882 0.2315
Onchocerca volvulus 0.0035 0.0062 0.0115
Echinococcus multilocularis cpg binding protein 0.0031 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0042 0.0088 0.0088
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0266 0.0882 0.0882
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0088 0.0231
Leishmania major i/6 autoantigen-like protein 0.013 0.0398 0.0737
Trypanosoma cruzi cruzipain precursor, putative 0.0334 0.1124 0.1124
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Onchocerca volvulus 0.0035 0.0062 0.0115
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0187 0.0601 0.1577
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.013 0.0398 0.0398
Entamoeba histolytica calmodulin, putative 0.013 0.0398 0.1046
Echinococcus granulosus tissue type plasminogen activator 0.0046 0.0101 0.0101
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.2765
Loa Loa (eye worm) calpain family protein 1 0.2123 0.7482 0.7482
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.013 0.0398 0.1046
Brugia malayi PXA domain containing protein 0.0042 0.0088 0.0088
Plasmodium vivax vivapain-2 0.1089 0.3809 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Schistosoma mansoni mitochondrial solute carrier 0.013 0.0398 0.0398
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1089 0.3809 0.3809
Trypanosoma brucei proteasome subunit beta type-5, putative 0.009 0.0256 0.0473
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0266 0.0882 0.2315
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Trichomonas vaginalis calpain, putative 0.0234 0.0767 0.2015
Leishmania major calpain family cysteine protease-like protein 0.0234 0.0767 0.1419
Brugia malayi EF hand family protein 0.0132 0.0407 0.0407
Onchocerca volvulus 0.003 0.0043 0.008
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0015 0.0015
Trypanosoma brucei Silent information regulator 2 related protein 3 0.007 0.0187 0.0346
Leishmania major oligopeptidase b 0.0629 0.2173 0.4019
Echinococcus granulosus Mastin 0.0081 0.0225 0.0225
Echinococcus granulosus geminin 0.0165 0.0525 0.0525
Brugia malayi histone deacetylase 3 (HD3) 0.0087 0.0248 0.0248
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0006 0.0013
Leishmania major cathepsin L-like protease 0.1089 0.3809 0.7046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0015 0.0015
Schistosoma mansoni calpain-7 (C02 family) 0.0799 0.2776 0.2776
Toxoplasma gondii cathepsin CPC1 0.0266 0.0882 0.1631
Loa Loa (eye worm) hypothetical protein 0.0093 0.0269 0.0269
Toxoplasma gondii histone deacetylase SIR2-like 0.007 0.0187 0.0346
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0399 0.1355 0.1355
Schistosoma mansoni cathepsin S (C01 family) 0.0266 0.0882 0.0882
Brugia malayi Trypsin-like protease protein 5 0.0081 0.0225 0.0225
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.06 0.2069 0.3826
Trypanosoma cruzi calmodulin, putative 0.013 0.0398 0.0398
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0267 0.0267
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0014 0.0036
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0266 0.0882 0.2315
Plasmodium falciparum serine repeat antigen 4 0.0266 0.0882 0.2315
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0088 0.0088
Echinococcus granulosus calpain 5 0.0796 0.2765 0.2765
Giardia lamblia Cathepsin B precursor 0.0266 0.0882 0.2382
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0021 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0046 0.0101 0.0186
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0062 0.0062
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Giardia lamblia Cysteine protease 0.0266 0.0882 0.2382
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0278 0.0926 0.0926
Schistosoma mansoni cpg binding protein 0.003 0.0043 0.0043
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0014 0.0036
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.2838 0.2838
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0088 0.0088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0248 0.082 0.1729
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0225
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0273 0.0908 0.0908
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0234 0.0767 0.0767
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0015 0.0015
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1089 0.3809 0.3809
Chlamydia trachomatis glycogen phosphorylase 0.0112 0.0336 0.5
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0187 0.0601 0.1577
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Giardia lamblia Hypothetical protein 0.0266 0.0882 0.2382
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.06 0.2069 0.3826
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0062 0.0163
Plasmodium vivax plasmepsin V, putative 0.003 0.0044 0.0114
Plasmodium falciparum histone deacetylase, putative 0.0098 0.0286 0.0752
Mycobacterium tuberculosis Conserved protein 0.0248 0.082 0.1729
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.013 0.0398 0.0398
Echinococcus multilocularis inhibitor of apoptosis protein 0.018 0.0576 0.0576
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.2765
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1059 0.3702 0.3702
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0234 0.0767 0.0767
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0266 0.0882 0.2315
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.007 0.0187 0.0491
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0006 0.0006
Brugia malayi NAD-dependent deacetylase SIRT1 0.0302 0.1012 0.1012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Plasmodium vivax unspecified product 0.06 0.2069 0.5431
Trichomonas vaginalis centrin, putative 0.013 0.0398 0.1046
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0248 0.0651
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0062 0.0115
Trypanosoma cruzi cysteine proteinase, putative 0.06 0.2069 0.2069
Trypanosoma brucei proteasome beta 6 subunit 0.007 0.0185 0.0342
Onchocerca volvulus 0.0081 0.0225 0.0416
Onchocerca volvulus 0.003 0.0043 0.008
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1539 0.5406 0.5406
Plasmodium falciparum histone deacetylase 2 0.0098 0.0286 0.0752
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.007 0.0185 0.0342
Entamoeba histolytica prolyl oligopeptidase family protein 0.0187 0.0601 0.1577
Loa Loa (eye worm) hypothetical protein 0.0087 0.0248 0.0248
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0062 0.0131
Schistosoma mansoni hypothetical protein 0.013 0.0398 0.0398
Onchocerca volvulus 0.018 0.0576 0.1066
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.013 0.0398 0.0398
Brugia malayi Peptidase family M13 containing protein 0.0093 0.0269 0.0269
Toxoplasma gondii aspartyl protease ASP1 0.003 0.0044 0.008
Plasmodium vivax vivapain-2 0.1089 0.3809 1
Brugia malayi hypothetical protein 0.0081 0.0225 0.0225
Giardia lamblia Hypothetical protein 0.0273 0.0908 0.2453
Echinococcus multilocularis calcium uptake protein 1 0.0132 0.0407 0.0407
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2253 0.7943 0.7943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0266 0.0882 0.2315
Toxoplasma gondii hypothetical protein 0.0234 0.0767 0.1419
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.007 0.0187 0.0491
Echinococcus granulosus expressed protein 0.0825 0.2869 0.2869
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0234 0.0767 0.1419
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0088 0.0088
Brugia malayi transcriptional regulator, Sir2 family protein 0.007 0.0187 0.0187
Loa Loa (eye worm) ctsf protein 0.1089 0.3809 0.3809
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0015 0.0015
Brugia malayi calpain 5 0.0562 0.1935 0.1935
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0015 0.0015
Entamoeba histolytica calmodulin, putative 0.013 0.0398 0.1046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0266 0.0882 0.2315
Brugia malayi cathepsin L-like cysteine proteinase 0.0266 0.0882 0.0882
Trichomonas vaginalis centrin, putative 0.013 0.0398 0.1046
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.013 0.0398 0.0737
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0234 0.0767 0.0767
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0248 0.0651
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0018 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0401 0.1846
Brugia malayi Histone deacetylase family protein 0.0098 0.0286 0.0286
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0006 0.0006
Loa Loa (eye worm) calpain 0.0796 0.2765 0.2765
Schistosoma mansoni hypothetical protein 0.0053 0.0125 0.0125
Giardia lamblia Cathepsin B precursor 0.0266 0.0882 0.2382
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0266 0.0882 0.0882
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0006 0.0017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0248 0.082 0.1729
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Loa Loa (eye worm) hypothetical protein 0.0093 0.0269 0.0269
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0286 0.0286
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0234 0.0767 0.2015
Loa Loa (eye worm) hypothetical protein 0.0091 0.0262 0.0262
Echinococcus granulosus baculoviral IAP repeat containing protein 0.018 0.0576 0.0576
Leishmania major kinesin, putative 0.0562 0.1935 0.358
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.013 0.0398 0.1046
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0014 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0187 0.0601 0.1577
Entamoeba histolytica hypothetical protein, conserved 0.0187 0.0601 0.1577
Onchocerca volvulus Peroxidase homolog 0.0169 0.054 0.0998
Brugia malayi carbohydrate phosphorylase 0.0112 0.0336 0.0336
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0398 0.1046
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0062 0.0131
Brugia malayi Protein kinase domain containing protein 0.0046 0.0101 0.0101
Trypanosoma brucei centrin-3 0.0133 0.0411 0.076
Loa Loa (eye worm) beta-lactamase 0.0035 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0334 0.1124 0.1124
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0334 0.1124 0.1124
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0286 0.0286
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0266 0.0882 0.2382
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0302 0.1012 0.1012
Onchocerca volvulus 0.003 0.0043 0.008
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0266 0.0882 0.0882
Brugia malayi MH2 domain containing protein 0.0121 0.0369 0.0369
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.013 0.0398 0.0398
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.007 0.0187 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Entamoeba histolytica hypothetical protein 0.0042 0.0088 0.0231
Echinococcus granulosus cathepsin b 0.2831 1 1
Echinococcus granulosus proteasome prosome macropain subunit beta 0.007 0.0185 0.0185
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Giardia lamblia Cathepsin B precursor 0.1059 0.3702 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0302 0.1012 0.2656
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0088 0.0088
Plasmodium falciparum cysteine proteinase falcipain 3 0.1089 0.3809 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0267 0.0267
Entamoeba histolytica calcium binding family protein 0.013 0.0398 0.1046
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.011 0.0288
Brugia malayi transcriptional regulator, Sir2 family protein 0.007 0.0187 0.0187
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Loa Loa (eye worm) hypothetical protein 0.1889 0.6652 0.6652
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0302 0.1012 0.2656
Brugia malayi Peroxidasin 0.0169 0.054 0.054
Leishmania major hypothetical protein, conserved 0.0035 0.0062 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0062 0.0062
Entamoeba histolytica calcium-binding protein, putative 0.013 0.0398 0.1046
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0278 0.0926 0.0926
Schistosoma mansoni cpg binding protein 0.0031 0.0049 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.06 0.2069 0.2069
Plasmodium falciparum plasmepsin X 0.0109 0.0324 0.0849
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0266 0.0882 0.2315
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2831 1 1
Onchocerca volvulus 0.013 0.0398 0.0737
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.06 0.2069 0.5431
Leishmania major cysteine peptidase A (CPA) 0.1089 0.3809 0.7046
Trichomonas vaginalis myosin light chain 1, putative 0.013 0.0398 0.1046
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Plasmodium falciparum transcriptional regulatory protein sir2a 0.007 0.0187 0.0491
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0266 0.0882 0.2315
Echinococcus multilocularis calpain family protein 1, d 0.1561 0.5484 0.5484
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0369 0.0369
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.013 0.0401 0.0401
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0014 0.0036
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0062 0.0062
Onchocerca volvulus Cell death protein 3 homolog 0.0095 0.0273 0.0506
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0015 0.0015
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0234 0.0767 0.0767
Brugia malayi cathepsin F-like cysteine proteinase 0.0266 0.0882 0.0882
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0266 0.0882 0.2315
Onchocerca volvulus 0.0167 0.0531 0.0982
Echinococcus multilocularis endothelin converting enzyme 1 0.0093 0.0269 0.0269
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0091 0.0238
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0399 0.1355 0.1355
Schistosoma mansoni cathepsin s 0.0334 0.1124 0.1124
Echinococcus granulosus cathepsin L 0.06 0.2069 0.2069
Onchocerca volvulus 0.003 0.0043 0.008
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0234 0.0767 0.1419
Giardia lamblia Cathepsin L-like protease 0.0266 0.0882 0.2382
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Echinococcus granulosus cathepsin l1 0.1089 0.3809 0.3809
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0015 0.0015
Schistosoma mansoni histone deacetylase hda2 0.0104 0.0308 0.0308
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0266 0.0882 0.0882
Toxoplasma gondii subtilisin SUB12 0.003 0.0043 0.008
Schistosoma mansoni caspase-7 (C14 family) 0.0095 0.0273 0.0273
Trypanosoma cruzi I/6 autoantigen, putative 0.013 0.0398 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0398 0.1046
Schistosoma mansoni glycogen phosphorylase 0.0048 0.011 0.011
Giardia lamblia Serine peptidase, putative 0.0021 0.0014 0.0037
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0028 0.0052
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0062 0.0131
Schistosoma mansoni centrin 0.013 0.0398 0.0398
Mycobacterium leprae proteasome (beta subunit) PrcB 0.009 0.0256 0.1178
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0062 0.0062
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0043 0.0043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0796 0.2765 0.2765
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0015 0.0015
Loa Loa (eye worm) prolyl oligopeptidase 0.0187 0.0601 0.0601
Giardia lamblia Thymus-specific serine protease precursor 0.0021 0.0014 0.0037
Entamoeba histolytica cysteine protease, putative 0.0266 0.0882 0.2315
Echinococcus granulosus calpain 0.0796 0.2765 0.2765
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0248 0.0651
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Loa Loa (eye worm) transcriptional regulator 0.007 0.0187 0.0187
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0015 0.0015
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0043 0.008
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0006 0.0017
Schistosoma mansoni peroxidasin 0.0169 0.054 0.054
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0302 0.1012 0.2656
Brugia malayi beta-lactamase family protein 0.0035 0.0062 0.0062
Brugia malayi proteasome subunit beta type 2 0.0043 0.0091 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Loa Loa (eye worm) hypothetical protein 0.0258 0.0855 0.0855
Leishmania major cathepsin L-like protease 0.1089 0.3809 0.7046
Schistosoma mansoni rab 0.013 0.0398 0.0398
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0756 0.2623 0.6885
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Plasmodium vivax SET domain protein, putative 0.0094 0.0272 0.0713
Echinococcus multilocularis cathepsin L 0.0266 0.0882 0.0882
Brugia malayi hypothetical protein 0.003 0.0044 0.0044
Echinococcus granulosus cathepsin L cysteine protease 0.06 0.2069 0.2069
Brugia malayi Papain family cysteine protease containing protein 0.1089 0.3809 0.3809
Onchocerca volvulus 0.1089 0.3809 0.7046
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Trypanosoma brucei histone deacetylase 3 0.0098 0.0286 0.053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0062 0.0131
Schistosoma mansoni memapsin-2 (A01 family) 0.0477 0.1631 0.1631
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Brugia malayi programmed cell death protein 6 0.013 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0044 0.0114
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.003 0.0044 0.008
Onchocerca volvulus Cathepsin F homolog 0.1089 0.3809 0.7046
Onchocerca volvulus 0.0742 0.2575 0.4763
Brugia malayi CXXC zinc finger family protein 0.003 0.0043 0.0043
Echinococcus multilocularis histone deacetylase 3 0.0087 0.0248 0.0248
Schistosoma mansoni hypothetical protein 0.0081 0.0225 0.0225
Leishmania major cytochrome p450-like protein 0.0035 0.0062 0.0114
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Echinococcus multilocularis calmodulin 0.013 0.0398 0.0398
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.009 0.0256 0.0256
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0273 0.0908 0.2384
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Onchocerca volvulus 0.0046 0.0102 0.0188
Echinococcus multilocularis EF hand domain containing family member A2 0.0132 0.0407 0.0407
Brugia malayi Pre-SET motif family protein 0.0652 0.2254 0.2254
Brugia malayi Histone deacetylase family protein 0.0098 0.0286 0.0286
Brugia malayi PXA domain containing protein 0.0042 0.0088 0.0088
Trypanosoma brucei hypothetical protein, conserved 0.013 0.0398 0.0737
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.4179 0.4179
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.003 0.0044 0.0114
Schistosoma mansoni ef hand domain family member A2 0.013 0.0398 0.0398
Plasmodium falciparum serine repeat antigen 2 0.0266 0.0882 0.2315
Echinococcus multilocularis glycogen phosphorylase 0.0112 0.0336 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Onchocerca volvulus 0.0055 0.0132 0.0243
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0088 0.0088
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0091 0.0245
Entamoeba histolytica cysteine protease, putative 0.0266 0.0882 0.2315
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0088 0.0088
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0021 0.0014 0.0014
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0273 0.0908 0.168
Loa Loa (eye worm) hypothetical protein 0.0035 0.0062 0.0062
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Echinococcus multilocularis peroxidasin 0.0169 0.054 0.054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2831 1 1
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0105 0.0105
Entamoeba histolytica cysteine proteinase, putative 0.0756 0.2623 0.6885
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0188
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Onchocerca volvulus 0.013 0.0398 0.0737
Plasmodium vivax histone deacetylase, putative 0.0098 0.0286 0.0752
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0015 0.0015
Brugia malayi Animal haem peroxidase family protein 0.0169 0.054 0.054
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0014 0.0014
Schistosoma mansoni histone deacetylase 0.0087 0.0248 0.0248
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.06 0.2069 0.2069
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Leishmania major silent information regulator 2, putative 0.0273 0.0908 0.168
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0266 0.0882 0.0882
Brugia malayi proteasome subunit beta type 1 0.007 0.0185 0.0185
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0266 0.0882 0.2315
Giardia lamblia Cathepsin L precursor 0.0266 0.0882 0.2382
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0401 0.0401
Leishmania major histone deacetylase, putative 0.0087 0.0248 0.0459
Schistosoma mansoni chromatin regulatory protein sir2 0.0273 0.0908 0.0908
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0043 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.5115
Trypanosoma brucei calpain, putative 0.0234 0.0767 0.1419
Toxoplasma gondii troponin c, isotype gamma, putative 0.013 0.0398 0.0737
Toxoplasma gondii cathepsin CPL 0.1089 0.3809 0.7046
Schistosoma mansoni neuronal calcium sensor 0.013 0.0398 0.0398
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0024 0.0024
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0248 0.0651
Echinococcus multilocularis caspase 2 0.0095 0.0273 0.0273
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Trypanosoma brucei calpain, putative 0.0234 0.0767 0.1419
Echinococcus granulosus apoptotic protease activating factor 1 0.0095 0.0273 0.0273
Trypanosoma brucei SIR2-like protein 4, putative 0.007 0.0187 0.0346
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0015 0.0015
Plasmodium falciparum plasmepsin III 0.003 0.0044 0.0114
Echinococcus granulosus histone deacetylase 8 0.0042 0.0087 0.0087
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.5115
Echinococcus granulosus caspase 2 0.0095 0.0273 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0062 0.0062
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0015 0.0028
Onchocerca volvulus 0.1089 0.3809 0.7046
Toxoplasma gondii hypothetical protein 0.0187 0.0601 0.1111
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.007 0.0187 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.5115
Trypanosoma brucei histone deacetylase 4 0.0098 0.0286 0.053
Giardia lamblia Cathepsin B precursor 0.1059 0.3702 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0266 0.0882 0.2315
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0028 0.0028
Loa Loa (eye worm) histone deacetylase 3 0.0087 0.0248 0.0248
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Brugia malayi hypothetical protein 0.0042 0.0088 0.0088
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0248 0.0248
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0091 0.0238
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0015 0.0015
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0043 0.008
Toxoplasma gondii aspartyl protease ASP3 0.0109 0.0324 0.0598
Echinococcus granulosus cathepsin L 0.0266 0.0882 0.0882
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0015 0.0015
Schistosoma mansoni neuronal calcium sensor 0.013 0.0398 0.0398
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0266 0.0882 0.2315
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0087 0.0087
Brugia malayi beta-lactamase 0.0035 0.0062 0.0062
Schistosoma mansoni chromatin regulatory protein sir2 0.007 0.0187 0.0187
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Toxoplasma gondii histone deacetylase HDAC2 0.0087 0.0248 0.0459
Onchocerca volvulus 0.0169 0.054 0.0998
Echinococcus multilocularis programmed cell death protein 0.0133 0.0411 0.0411
Echinococcus multilocularis proteasome (prosome, macropain) 0.009 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0286 0.0286
Brugia malayi Thioredoxin family protein 0.0248 0.082 0.082
Brugia malayi calpain 5 0.0234 0.0767 0.0767
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0015 0.0015
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0088 0.0088
Leishmania major cathepsin L-like protease 0.1089 0.3809 0.7046
Giardia lamblia Cysteine protease 0.0266 0.0882 0.2382
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Onchocerca volvulus 0.003 0.0043 0.008
Plasmodium vivax NAD-dependent deacetylase, putative 0.007 0.0187 0.0491
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0796 0.2765 0.2765
Entamoeba histolytica cysteine protease, putative 0.0266 0.0882 0.2315
Loa Loa (eye worm) aspartyl protease 6 0.003 0.0044 0.0044
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0188
Mycobacterium ulcerans NAD-dependent deacetylase 0.007 0.0187 0.0861
Plasmodium falciparum proteasome subunit beta type-5 0.009 0.0256 0.0672
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Toxoplasma gondii PAN domain-containing protein 0.003 0.0043 0.008
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0028 0.0052
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0093 0.0269 0.0269
Echinococcus granulosus prolyl endopeptidase 0.1539 0.5406 0.5406
Loa Loa (eye worm) hypothetical protein 0.0046 0.0101 0.0101
Plasmodium vivax vivapain-1 0.06 0.2069 0.5431
Echinococcus multilocularis geminin 0.0165 0.0525 0.0525
Onchocerca volvulus 0.0081 0.0225 0.0416
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0087 0.0087
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0028 0.0052
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0015 0.0015
Entamoeba histolytica cysteine proteinase 1, putative 0.06 0.2069 0.5431
Echinococcus multilocularis cathepsin L 0.06 0.2069 0.2069
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0088 0.0088
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Leishmania major calmodulin, putative 0.013 0.0398 0.0737
Entamoeba histolytica glycogen phosphorylase, putative 0.0112 0.0336 0.0882
Loa Loa (eye worm) hypothetical protein 0.2831 1 1
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0088 0.0231
Plasmodium falciparum cysteine repeat modular protein 1 0.0046 0.0101 0.0264
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0062 0.0114
Onchocerca volvulus 0.0756 0.2623 0.4851
Echinococcus multilocularis glycoprotein Antigen 5 0.0081 0.0225 0.0225
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0006 0.0006
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0087 0.0087
Plasmodium vivax vivapain-3 0.06 0.2069 0.5431
Loa Loa (eye worm) prolyl oligopeptidase 0.0514 0.1765 0.1765
Brugia malayi Cathepsin L-like precursor 0.1089 0.3809 0.3809
Schistosoma mansoni histone deacetylase 0.0087 0.0248 0.0248
Brugia malayi prolyl oligopeptidase family protein 0.0187 0.0601 0.0601
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0266 0.0882 0.0882
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0629 0.2173 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Giardia lamblia Hypothetical protein 0.0248 0.082 0.2216
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Giardia lamblia Alanyl dipeptidyl peptidase 0.0187 0.0601 0.1623
Echinococcus granulosus cpg binding protein 0.0031 0.0049 0.0049
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0088 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0015 0.0015
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0286 0.0286
Loa Loa (eye worm) EF hand family protein 0.013 0.0398 0.0398
Plasmodium falciparum plasmepsin VII 0.003 0.0044 0.0114
Schistosoma mansoni calmodulin related calcium binding protein 0.013 0.0398 0.0398
Plasmodium falciparum plasmepsin VI 0.003 0.0044 0.0114
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.007 0.0185 0.0185
Brugia malayi hypothetical protein 0.0258 0.0855 0.0855
Trypanosoma brucei cysteine peptidase, putative 0.0234 0.0767 0.1419
Echinococcus multilocularis Mastin 0.0081 0.0225 0.0225
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0278 0.0926 0.1712
Onchocerca volvulus 0.1089 0.3809 0.7046
Echinococcus granulosus EF HAND 1 calcium binding site 0.013 0.0398 0.0398
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0266 0.0882 0.2315
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0514 0.1765 0.1765
Trypanosoma brucei Component of motile flagella 41 0.013 0.0398 0.0737
Entamoeba histolytica cysteine protease, putative 0.0266 0.0882 0.2315
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0088 0.0088
Onchocerca volvulus 0.0046 0.0101 0.0186
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0015 0.0015
Trypanosoma cruzi caltractin, putative 0.013 0.0398 0.0398
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Trypanosoma cruzi major cysteine proteinase, putative 0.037 0.1251 0.1251
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0266 0.0882 0.0882
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Plasmodium vivax unspecified product 0.0266 0.0882 0.2315
Onchocerca volvulus 0.003 0.0043 0.008
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0088 0.0088
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0272 0.0272
Giardia lamblia Encystation-specific protease 0.0266 0.0882 0.2382
Brugia malayi histone deacetylase 1 (HD1) 0.0087 0.0248 0.0248
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0272 0.0272
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0266 0.0882 0.2315
Trichomonas vaginalis calmodulin, putative 0.013 0.0398 0.1046
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0081 0.0225 0.0225
Schistosoma mansoni inhibitor of apoptosis protein 0.018 0.0576 0.0576
Loa Loa (eye worm) hypothetical protein 0.0094 0.0272 0.0272
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0266 0.0882 0.2315
Brugia malayi Papain family cysteine protease containing protein 0.0266 0.0882 0.0882
Brugia malayi Cathepsin L-like precursor 0.1089 0.3809 0.3809
Loa Loa (eye worm) hypothetical protein 0.0234 0.0767 0.0767
Echinococcus granulosus glycogen phosphorylase 0.0112 0.0336 0.0336
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0046 0.0101 0.0264
Echinococcus granulosus endothelin converting enzyme 1 0.0093 0.0269 0.0269
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0088 0.0088
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.013 0.0401 0.0846
Trypanosoma brucei calpain-like protein, putative 0.0796 0.2765 0.5115
Toxoplasma gondii cathepsin B 0.1059 0.3702 0.6847
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2831 1 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Schistosoma mansoni neuronal calcium sensor 0.013 0.0398 0.0398
Brugia malayi Cathepsin L-like precursor 0.1089 0.3809 0.3809
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0182 0.0182
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Entamoeba histolytica cysteine proteinase 2 0.06 0.2069 0.5431
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0015 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0272 0.0272
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0266 0.0882 0.0882
Entamoeba histolytica calpain large subunit domain III containing protein 0.0562 0.1935 0.5081
Onchocerca volvulus 0.003 0.0043 0.008
Plasmodium falciparum proteasome subunit beta type-1, putative 0.007 0.0185 0.0485
Trypanosoma brucei mitochondrial calcium uptake 1 0.013 0.0398 0.0737
Brugia malayi gamma-secretase subunit aph-1 0.0254 0.084 0.084
Plasmodium falciparum serine repeat antigen 6 0.0266 0.0882 0.2315
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0036
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Loa Loa (eye worm) hypothetical protein 0.0095 0.0273 0.0273
Schistosoma mansoni chromatin regulatory protein sir2 0.007 0.0187 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0015 0.0015
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.007 0.0187 0.0187
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0629 0.2173 1
Loa Loa (eye worm) histone deacetylase 1 0.0087 0.0248 0.0248
Echinococcus granulosus neuronal calcium sensor 0.013 0.0398 0.0398
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0234 0.0767 0.2015
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0399 0.1355 0.1355
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0266 0.0882 0.0882
Loa Loa (eye worm) calpain 5 0.0562 0.1935 0.1935
Trypanosoma brucei prolyl oligopeptidase, putative 0.0629 0.2173 0.4019
Schistosoma mansoni hypothetical protein 0.0248 0.082 0.082
Trypanosoma cruzi kinesin, putative 0.0562 0.1935 0.1935
Toxoplasma gondii cathepsin CPC2 0.0266 0.0882 0.1631
Plasmodium falciparum serine repeat antigen 1 0.0266 0.0882 0.2315
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0015 0.0015
Plasmodium vivax histone deacetylase, putative 0.0042 0.0087 0.0229
Onchocerca volvulus 0.0053 0.0125 0.023
Leishmania major proteasome beta 5 subunit, putative 0.009 0.0256 0.0473
Schistosoma mansoni hypothetical protein 0.0422 0.1437 0.1437
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0006 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Echinococcus granulosus cathepsin b 0.2831 1 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Plasmodium falciparum peptidase, putative 0.0187 0.0601 0.1577
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0015 0.0015
Giardia lamblia Cathepsin B precursor 0.0266 0.0882 0.2382
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0266 0.0882 0.2382
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.0767
Echinococcus granulosus dnaJ subfamily B 0.0422 0.1437 0.1437
Loa Loa (eye worm) hypothetical protein 0.0266 0.0882 0.0882
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Loa Loa (eye worm) hypothetical protein 0.2123 0.7482 0.7482
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0101 0.0101
Trichomonas vaginalis esterase, putative 0.0035 0.0062 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1089 0.3809 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0015 0.0015
Brugia malayi Eukaryotic aspartyl protease family protein 0.003 0.0044 0.0044
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.013 0.0401 0.0742
Loa Loa (eye worm) hypothetical protein 0.0035 0.0062 0.0062
Leishmania major centrin, putative 0.013 0.0398 0.0737
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0015 0.0015
Toxoplasma gondii kringle domain-containing protein 0.0046 0.0101 0.0186
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0088 0.0088
Toxoplasma gondii aspartyl protease 0.003 0.0044 0.008
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0149 0.0276
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0256 0.0672
Brugia malayi nuclear hormone receptor 0.0022 0.0015 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0267 0.0267
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0091 0.0168
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0796 0.2765 0.2765
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0279 0.093 0.2442
Brugia malayi Serine carboxypeptidase S28 family protein 0.0021 0.0014 0.0014
Schistosoma mansoni peroxidasin 0.0169 0.054 0.054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0272 0.0272
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0018 0.0018
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0234 0.0767 0.1419
Loa Loa (eye worm) hypothetical protein 0.0169 0.054 0.054
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.007 0.0187 0.0491
Giardia lamblia Cathepsin L-like protease 0.0266 0.0882 0.2382
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Schistosoma mansoni cathepsin D (A01 family) 0.0122 0.037 0.037
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0266 0.0882 0.2315
Plasmodium falciparum flap endonuclease 1 0.0026 0.0028 0.0074
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.0088 0.0163
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0225
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0088 0.0088
Brugia malayi Trypsin family protein 0.0081 0.0225 0.0225
Onchocerca volvulus 0.0081 0.0225 0.0416
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0088 0.0088
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Plasmodium vivax plasmepsin IV, putative 0.003 0.0044 0.0114
Toxoplasma gondii hypothetical protein 0.003 0.0043 0.008
Brugia malayi Cathepsin L-like precursor 0.1089 0.3809 0.3809
Schistosoma mansoni chromatin regulatory protein sir2 0.0302 0.1012 0.1012
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0088 0.0231
Entamoeba histolytica prolyl oligopeptidase family protein 0.0187 0.0601 0.1577
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.007 0.0187 0.0491
Plasmodium vivax serine-repeat antigen (SERA) 0.0266 0.0882 0.2315
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Trypanosoma cruzi cysteine protease, putative 0.06 0.2069 0.2069
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0266 0.0882 0.0882
Schistosoma mansoni calmodulin 0.013 0.0398 0.0398
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Giardia lamblia Transglutaminase/protease, putative 0.0248 0.082 0.2216
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0266 0.0882 0.2315
Echinococcus granulosus gamma secretase subunit aph 1 0.0254 0.084 0.084
Entamoeba histolytica cysteine proteinase, putative 0.06 0.2069 0.5431
Trichomonas vaginalis calmodulin, putative 0.013 0.0398 0.1046
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Loa Loa (eye worm) hypothetical protein 0.0266 0.0882 0.0882
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0796 0.2765 0.5115
Loa Loa (eye worm) transcriptional regulator 0.007 0.0187 0.0187
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0185 0.0185
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.013 0.0398 0.1046
Brugia malayi cathepsin F-like cysteine proteinase 0.0334 0.1124 0.1124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0015 0.0015
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0401 0.0401
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0036
Onchocerca volvulus 0.003 0.0043 0.008
Plasmodium vivax centrin-1, putative 0.013 0.0398 0.1046
Trypanosoma brucei calmodulin, putative 0.0132 0.0407 0.0752
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0286 0.0286
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1089 0.3809 0.3809
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Echinococcus multilocularis acylamino acid releasing enzyme 0.0187 0.0601 0.0601
Schistosoma mansoni glycogen phosphorylase 0.0112 0.0336 0.0336
Schistosoma mansoni cpg binding protein 0.0031 0.0049 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Toxoplasma gondii microneme protein, putative 0.003 0.0043 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0401 0.1846
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0278 0.0926 0.1712
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Leishmania major cathepsin L-like protease 0.1089 0.3809 0.7046
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0248 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0062 0.0062
Brugia malayi Papain family cysteine protease containing protein 0.0266 0.0882 0.0882
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0629 0.2173 0.4581
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0088 0.0088
Toxoplasma gondii PAN domain-containing protein 0.003 0.0043 0.008
Brugia malayi hypothetical protein 0.0042 0.0088 0.0088
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Echinococcus granulosus acylamino acid releasing enzyme 0.0187 0.0601 0.0601
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.0256 0.0256
Trypanosoma brucei centrin, putative 0.013 0.0398 0.0737
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.0225 0.0225
Plasmodium falciparum serine repeat antigen 3 0.0266 0.0882 0.2315
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1089 0.3809 1
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0266 0.0882 0.0882
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0105 0.0105
Trypanosoma brucei kinesin, putative 0.0562 0.1935 0.358
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Mycobacterium leprae Probable lipase LipE 0.0035 0.0062 0.0285
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0015 0.0015
Echinococcus multilocularis cathepsin L cysteine protease 0.1089 0.3809 0.3809
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.054 0.054
Echinococcus multilocularis calpain 7 (C02 family) 0.0796 0.2765 0.2765
Echinococcus granulosus inhibitor of apoptosis protein 0.018 0.0576 0.0576
Loa Loa (eye worm) aspartic protease BmAsp-2 0.003 0.0044 0.0044
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0652 0.2254 0.2254
Mycobacterium tuberculosis Hypothetical protein 0.0248 0.082 0.1729
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.0018 0.0018
Mycobacterium ulcerans hypothetical protein 0.0248 0.082 0.3776
Brugia malayi Cathepsin L-like precursor 0.1089 0.3809 0.3809
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0015 0.0015
Entamoeba histolytica proteasome subunit beta type 1, putative 0.007 0.0185 0.0485
Loa Loa (eye worm) hypothetical protein 0.0756 0.2623 0.2623
Echinococcus granulosus EF hand domain containing family member A2 0.013 0.0398 0.0398
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0043 0.0043
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0185 0.0185
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0182 0.0182
Mycobacterium ulcerans transglutaminase family protein 0.0248 0.082 0.3776
Trichomonas vaginalis conserved hypothetical protein 0.0187 0.0601 0.1577
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2253 0.7943 0.7943
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0043
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0062 0.0285
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Trichomonas vaginalis calmodulin, putative 0.013 0.0398 0.1046
Plasmodium vivax hypothetical protein, conserved 0.0132 0.0407 0.1068
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0062 0.0163
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0014 0.0036
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.013 0.0398 0.0398
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1539 0.5406 1
Toxoplasma gondii histone deacetylase HDAC3 0.0087 0.0248 0.0459
Leishmania major hypothetical protein, conserved 0.013 0.0398 0.0737
Onchocerca volvulus 0.0081 0.0225 0.0416
Brugia malayi Calmodulin-like protein 0.013 0.0398 0.0398
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.007 0.0187 0.0491
Toxoplasma gondii PAN domain-containing protein 0.003 0.0043 0.008
Brugia malayi Flap endonuclease-1 0.0026 0.0028 0.0028
Echinococcus granulosus calmodulin 0.013 0.0398 0.0398
Plasmodium vivax proteasome subunit beta type-1, putative 0.007 0.0185 0.0485
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.011 0.0288
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1539 0.5406 0.5406
Loa Loa (eye worm) hypothetical protein 0.003 0.0044 0.0044
Schistosoma mansoni flap endonuclease-1 0.0023 0.0019 0.0019
Onchocerca volvulus Cathepsin L homolog 0.1089 0.3809 0.7046
Trypanosoma brucei calpain-like protein, putative 0.0796 0.2765 0.5115
Loa Loa (eye worm) hypothetical protein 0.0069 0.0182 0.0182
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0015 0.0015
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0015 0.0028
Loa Loa (eye worm) transcriptional regulator 0.0273 0.0908 0.0908
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Echinococcus multilocularis tissue type plasminogen activator 0.0046 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0334 0.1124 0.1124
Entamoeba histolytica cysteine protease, putative 0.0266 0.0882 0.2315
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0006 0.0006
Echinococcus granulosus chromatin regulatory protein sir2 0.0273 0.0908 0.0908
Schistosoma mansoni hypothetical protein 0.0081 0.0225 0.0225
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Giardia lamblia Proteasome subunit beta type 5 precursor 0.009 0.0256 0.0691
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1089 0.3809 1
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0514 0.1765 0.1765
Mycobacterium ulcerans hypothetical protein 0.0248 0.082 0.3776
Echinococcus granulosus cathepsin L cysteine proteinase 0.1089 0.3809 0.3809
Brugia malayi hypothetical protein 0.0095 0.0273 0.0273
Trypanosoma brucei protein I/6 0.013 0.0398 0.0737
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0006 0.0012
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0088 0.0088
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0091 0.0238
Loa Loa (eye worm) hypothetical protein 0.0266 0.0882 0.0882
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0015 0.0015
Echinococcus granulosus tumor protein p63 0.0373 0.1264 0.1264
Loa Loa (eye worm) hypothetical protein 0.0046 0.0102 0.0102
Brugia malayi beta-lactamase family protein 0.0035 0.0062 0.0062
Echinococcus granulosus histone deacetylase 6 0.0098 0.0286 0.0286
Brugia malayi cathepsin Z-like cysteine proteinase 0.0266 0.0882 0.0882
Loa Loa (eye worm) cathepsin B 0.1059 0.3702 0.3702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.06 0.2069 0.5431
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0088 0.0231
Plasmodium vivax aspartyl protease, putative 0.0109 0.0324 0.0849
Brugia malayi calpain family protein 1 0.2123 0.7482 0.7482
Onchocerca volvulus 0.0248 0.082 0.1517
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0266 0.0882 0.2315
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0266 0.0882 0.0882
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0225
Brugia malayi Animal haem peroxidase family protein 0.0169 0.054 0.054
Schistosoma mansoni neprilysin-2 (M13 family) 0.0047 0.0105 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0234 0.0767 0.0767
Echinococcus multilocularis survival motor neuron protein 1 0.0258 0.0855 0.0855
Leishmania major centrin, putative 0.013 0.0398 0.0737
Entamoeba histolytica prolyl oligopeptidase family protein 0.0187 0.0601 0.1577
Trypanosoma cruzi calmodulin, putative 0.013 0.0398 0.0398
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0234 0.0767 0.0767
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1089 0.3809 0.3809
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.06 0.2069 0.2069
Toxoplasma gondii peptidase family M13 protein 0.0093 0.0269 0.0497
Toxoplasma gondii microneme protein MIC17B 0.003 0.0043 0.008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2831 1 1
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0088 0.0088
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0087 0.0087
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0278 0.0926 0.0926
Brugia malayi hypothetical protein 0.0167 0.0531 0.0531
Brugia malayi aspartic protease BmAsp-1, identical 0.003 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0014
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0062 0.0285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Trypanosoma brucei caltractin, putative 0.0133 0.0411 0.076
Echinococcus granulosus Transglutaminase 0.0248 0.082 0.082
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0234 0.0767 0.1419
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.013 0.0401 0.0401
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.007 0.0187 0.0187
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0105 0.0105
Brugia malayi calpain D 0.0234 0.0767 0.0767
Brugia malayi Trypsin family protein 0.0081 0.0225 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0273 0.0908 0.2384
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Plasmodium vivax serine-repeat antigen (SERA) 0.0266 0.0882 0.2315
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.007 0.0187 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0042 0.0088 0.0088
Schistosoma mansoni glycogen phosphorylase 0.0112 0.0336 0.0336
Toxoplasma gondii aldehyde dehydrogenase 0.013 0.0401 0.0742
Mycobacterium tuberculosis Conserved protein 0.0035 0.0062 0.0131
Loa Loa (eye worm) hypothetical protein 0.003 0.0044 0.0044
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2253 0.7943 0.7943
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Loa Loa (eye worm) glycogen phosphorylase 0.0112 0.0336 0.0336
Brugia malayi Cathepsin L-like cysteine proteinase 0.0756 0.2623 0.2623
Echinococcus multilocularis expressed protein 0.0825 0.2869 0.2869
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.0601 0.0601
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0188
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Entamoeba histolytica glycogen phosphorylase, putative 0.0112 0.0336 0.0882
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0091 0.0091
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0062 0.0284
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0187 0.0601 0.1577
Schistosoma mansoni calmodulin 0.013 0.0398 0.0398
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0014 0.0036
Giardia lamblia Transcriptional regulator, Sir2 family 0.007 0.0187 0.0505
Plasmodium vivax aspartyl protease, putative 0.0109 0.0324 0.0849
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0272 0.0503
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Echinococcus multilocularis calbindin 32 0.0132 0.0407 0.0407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.4179 0.7729
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0044 0.0044
Echinococcus granulosus neurocalcin 0.013 0.0398 0.0398
Schistosoma mansoni calpain-7 (C02 family) 0.0799 0.2776 0.2776
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.018 0.0576 0.0576
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0308 0.0308
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0091 0.0091
Schistosoma mansoni chromatin regulatory protein sir2 0.0273 0.0908 0.0908
Trichomonas vaginalis set domain proteins, putative 0.0742 0.2574 0.6757
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0062 0.0062
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0093 0.0269 0.0566
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0062 0.0163
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.0018 0.0018
Brugia malayi Cathepsin L-like precursor 0.1089 0.3809 0.3809
Echinococcus granulosus glycoprotein Antigen 5 0.0081 0.0225 0.0225
Schistosoma mansoni gamma-secretase subunit aph-1 0.0254 0.084 0.084
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0266 0.0882 0.2315
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0234 0.0767 0.0767
Loa Loa (eye worm) hypothetical protein 0.003 0.0044 0.0044
Toxoplasma gondii calmodulin CAM1 0.0132 0.0407 0.0752
Trypanosoma brucei Calpain-like protein 1.1 0.0234 0.0767 0.1419
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.013 0.0398 0.1046
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0266 0.0882 0.2382
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0015 0.0015
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0006 0.0012
Giardia lamblia Cathepsin L precursor 0.0266 0.0882 0.2382
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0882 0.2315
Echinococcus granulosus proteasome prosome macropain 0.009 0.0256 0.0256
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0257 0.0257
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0088 0.0088
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0047 0.0105 0.0105
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Entamoeba histolytica cysteine protease, putative 0.06 0.2069 0.5431
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.0272 0.0272
Loa Loa (eye worm) aspartic protease BmAsp-1 0.003 0.0044 0.0044
Leishmania major histone deacetylase, putative 0.0098 0.0286 0.053
Brugia malayi Cytochrome P450 family protein 0.0035 0.0062 0.0062
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.1089 0.3809 0.3809
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0132 0.0407 0.0407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Echinococcus granulosus calpain 7 C02 family 0.0796 0.2765 0.2765
Echinococcus multilocularis Transglutaminase 0.0248 0.082 0.082
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0062 0.0062
Trichomonas vaginalis calmodulin-2, putative 0.013 0.0398 0.1046
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0369 0.0369
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0125 0.0125
Echinococcus multilocularis histone deacetylase 7 0.0098 0.0286 0.0286
Mycobacterium leprae Conserved hypothetical protein 0.0248 0.082 0.3776
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0062 0.0062
Plasmodium falciparum cysteine proteinase falcipain 1 0.06 0.2069 0.5431
Trichomonas vaginalis hypothetical protein 0.0234 0.0767 0.2015
Entamoeba histolytica grainin 2 0.0133 0.0411 0.1079
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0273 0.0908 0.0908
Echinococcus granulosus peroxidasin 0.0169 0.054 0.054
Brugia malayi ecdysteroid receptor 0.0022 0.0015 0.0015
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0234 0.0767 0.0767
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.06 0.2069 0.2069
Echinococcus granulosus sarcoplasmic calcium binding protein 0.013 0.0398 0.0398
Echinococcus multilocularis neuronal calcium sensor 0.013 0.0398 0.0398
Giardia lamblia Sirtuin type 2 0.007 0.0187 0.0505
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Leishmania major calmodulin, putative 0.013 0.0398 0.0737
Onchocerca volvulus 0.0169 0.054 0.0998
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0289 0.0289
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Loa Loa (eye worm) fibroinase 0.1089 0.3809 0.3809
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0266 0.0882 0.2315
Brugia malayi transcriptional regulator, Sir2 family protein 0.0273 0.0908 0.0908
Toxoplasma gondii histone deacetylase HDAC1 0.0098 0.0286 0.053
Trypanosoma cruzi oligopeptidase b 0.0629 0.2173 0.2173
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0015 0.0028
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0088 0.0088
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0234 0.0767 0.2015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0062 0.0062
Trypanosoma brucei calmodulin, putative 0.013 0.0398 0.0737
Echinococcus granulosus calpain A 0.0796 0.2765 0.2765
Entamoeba histolytica cysteine proteinase, putative 0.1089 0.3809 1
Trypanosoma cruzi kinesin, putative 0.0562 0.1935 0.1935
Brugia malayi Animal haem peroxidase family protein 0.0169 0.054 0.054
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.018 0.0576 0.0576
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0088 0.0088
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.018 0.0576 0.0576
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0006 0.0006
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0088 0.0088
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0015 0.0015
Onchocerca volvulus Dual oxidase homolog 0.0169 0.054 0.0998
Leishmania major hypothetical protein, conserved 0.0132 0.0407 0.0752
Entamoeba histolytica cysteine proteinase, putative 0.06 0.2069 0.5431
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0266 0.0882 0.0882
Schistosoma mansoni hypothetical protein 0.013 0.0398 0.0398
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0062 0.0163
Trichomonas vaginalis calmodulin, putative 0.0133 0.0411 0.1079
Trichomonas vaginalis calcium binding proteins, putative 0.013 0.0398 0.1046
Echinococcus multilocularis calmodulin 0.013 0.0398 0.0398
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0015 0.0015
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0088 0.0088
Onchocerca volvulus 0.0169 0.054 0.0998
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.007 0.0187 0.0491
Giardia lamblia Proteasome subunit beta type 1 0.007 0.0185 0.0499
Leishmania major phospholipase c-like protein 0.013 0.0398 0.0737
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0278 0.0926 0.1712
Echinococcus granulosus calcium uptake protein 1 0.0132 0.0407 0.0407
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0015 0.0015
Plasmodium falciparum plasmepsin IV 0.003 0.0044 0.0114
Trypanosoma cruzi cysteine proteinase, putative 0.06 0.2069 0.2069
Echinococcus granulosus calumenin 0.0132 0.0407 0.0407
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.4179 0.4179
Echinococcus granulosus calbindin 32 0.0132 0.0407 0.0407
Brugia malayi Cathepsin L-like precursor 0.0334 0.1124 0.1124
Brugia malayi hypothetical protein 0.0091 0.0262 0.0262
Echinococcus multilocularis apoptotic protease activating factor 1 0.0095 0.0273 0.0273
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.003 0.0044 0.008
Plasmodium vivax unspecified product 0.0334 0.1124 0.2951
Leishmania major cathepsin L-like protease 0.1193 0.4179 0.7729
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0015 0.0015
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0289 0.0535
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0187 0.0601 0.1111
Brugia malayi prolyl oligopeptidase family protein 0.0514 0.1765 0.1765
Loa Loa (eye worm) hypothetical protein 0.0062 0.0158 0.0158
Echinococcus granulosus microtubule associated protein 2 0.1492 0.5238 0.5238
Trichomonas vaginalis peptide N-glycanase, putative 0.0248 0.082 0.2153
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0273 0.0908 0.0908
Mycobacterium ulcerans proteasome PrcB 0.009 0.0256 0.1178
Giardia lamblia Alanyl dipeptidyl peptidase 0.0187 0.0601 0.1623
Trypanosoma cruzi major cysteine proteinase, putative 0.0266 0.0882 0.0882
Onchocerca volvulus Glycogen phosphorylase homolog 0.0112 0.0336 0.0622
Brugia malayi Animal haem peroxidase family protein 0.0169 0.054 0.054
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0302 0.1012 0.2656
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.0225 0.0225
Onchocerca volvulus 0.0094 0.0272 0.0503
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0043 0.0043
Trypanosoma brucei prolyl endopeptidase 0.1539 0.5406 1
Brugia malayi aspartic protease BmAsp-2, identical 0.003 0.0044 0.0044
Loa Loa (eye worm) calpain D 0.0234 0.0767 0.0767
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0006 0.0006
Trichomonas vaginalis calmodulin, putative 0.013 0.0398 0.1046
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0286 0.0286
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0018 0.0018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.06 0.2069 0.2069
Toxoplasma gondii PAN domain-containing protein 0.003 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.0093 0.0269 0.0269
Echinococcus granulosus EF hand domain containing family member A2 0.0132 0.0407 0.0407
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0514 0.1765 0.3264
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0088 0.0231
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0006 0.0017
Toxoplasma gondii exonuclease III APE 0.0019 0.0006 0.0012
Echinococcus multilocularis calpain 0.0796 0.2765 0.2765
Loa Loa (eye worm) hypothetical protein 0.018 0.0576 0.0576
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.0018 0.0018
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0185 0.0485
Onchocerca volvulus Peroxidasin homolog 0.0169 0.054 0.0998
Entamoeba histolytica histone deacetylase, putative 0.0087 0.0248 0.0651
Onchocerca volvulus 0.1327 0.4654 0.8608
Loa Loa (eye worm) calpain family protein 1 0.1561 0.5484 0.5484
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Plasmodium falciparum serine repeat antigen 9 0.0266 0.0882 0.2315
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Schistosoma mansoni cathepsin F (C01 family) 0.1089 0.3809 0.3809
Toxoplasma gondii calcium-dependent protein kinase 0.0132 0.0407 0.0752
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Trypanosoma brucei calpain-like protein, putative 0.0796 0.2765 0.5115
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0062 0.0131
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0272 0.0272
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0044 0.0114
Loa Loa (eye worm) hypothetical protein 0.0302 0.1012 0.1012
Entamoeba histolytica glycogenphosphorylase, putative 0.0048 0.011 0.0288
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0278 0.0926 0.0926
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0088 0.0088
Toxoplasma gondii PAN domain-containing protein 0.003 0.0043 0.008
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0302 0.1012 0.1012
Entamoeba histolytica cysteine proteinase, putative 0.06 0.2069 0.5431
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0014 0.0036
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0091 0.0091
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0087 0.0161
Plasmodium falciparum calpain 0.0234 0.0767 0.2015
Entamoeba histolytica cysteine proteinase, putative 0.06 0.2069 0.5431
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Brugia malayi hypothetical protein 0.003 0.0044 0.0044
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0273 0.0908 0.2384
Echinococcus granulosus glycogen phosphorylase 0.0112 0.0336 0.0336
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.007 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.013 0.0398 0.0398
Giardia lamblia Glycogen phosphorylase 0.0112 0.0336 0.0908
Loa Loa (eye worm) hypothetical protein 0.0187 0.0601 0.0601
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.007 0.0185 0.0185
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0088 0.0088
Brugia malayi PAN domain containing protein 0.003 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0859 0.2992 0.2992
Loa Loa (eye worm) hypothetical protein 0.0266 0.0882 0.0882
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0081 0.0225 0.0225
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0272 0.0272
Echinococcus multilocularis neurocalcin 0.013 0.0398 0.0398
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0091 0.0168
Schistosoma mansoni neuronal calcium sensor 0.013 0.0398 0.0398
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2123 0.7482 0.7482
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0048 0.011 0.0505
Echinococcus multilocularis histone deacetylase 1 0.0087 0.0248 0.0248
Loa Loa (eye worm) proteasome subunit beta type 1 0.007 0.0185 0.0185
Echinococcus granulosus histone deacetylase 6 0.0098 0.0286 0.0286
Plasmodium vivax hypothetical protein, conserved 0.007 0.0187 0.0491
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0278 0.0926 0.1712
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.007 0.0187 0.0187
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0796 0.2765 0.2765
Trypanosoma brucei Calpain-like protein 2 0.0234 0.0767 0.1419
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0188
Echinococcus granulosus histone deacetylase 1 0.0087 0.0248 0.0248
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.018 0.0576 0.0576
Loa Loa (eye worm) hypothetical protein 0.0035 0.0062 0.0062
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0062 0.0131
Schistosoma mansoni hypothetical protein 0.0234 0.0767 0.0767
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0088 0.0088
Brugia malayi Pre-SET motif family protein 0.0094 0.0272 0.0272
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0021 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0167 0.0531 0.0531
Loa Loa (eye worm) histone deacetylase 0.0098 0.0286 0.0286
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2253 0.7943 0.7943
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0629 0.2173 0.2173
Onchocerca volvulus 0.003 0.0043 0.0079
Brugia malayi Cathepsin L-like precursor 0.0756 0.2623 0.2623
Giardia lamblia Hypothetical protein 0.0132 0.0407 0.1099
Echinococcus multilocularis EF HAND 1, calcium binding site 0.013 0.0398 0.0398
Plasmodium falciparum transcriptional regulatory protein sir2b 0.007 0.0187 0.0491
Mycobacterium leprae probable zinc metalloprotease 0.0093 0.0269 0.1237
Plasmodium falciparum plasmepsin V 0.003 0.0044 0.0114
Schistosoma mansoni ap endonuclease 0.0019 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0165 0.0525 0.0525
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0267 0.0267
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0028 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0015 0.0015
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Mycobacterium tuberculosis Probable peptidase 0.0629 0.2173 0.4581
Loa Loa (eye worm) hypothetical protein 0.1561 0.5484 0.5484
Loa Loa (eye worm) hypothetical protein 0.0035 0.0062 0.0062
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0014 0.0014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0796 0.2765 0.2765
Loa Loa (eye worm) hypothetical protein 0.0069 0.0182 0.0182
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0266 0.0882 0.2315
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0266 0.0882 0.2315
Toxoplasma gondii microneme protein MIC17A 0.003 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.0056 0.0137 0.0137
Toxoplasma gondii ABC1 family protein 0.0035 0.0062 0.0115
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0234 0.0767 0.1419
Onchocerca volvulus Cathepsin L homolog 0.0266 0.0882 0.1631
Plasmodium falciparum serine repeat antigen 5 0.0266 0.0882 0.2315
Giardia lamblia Cathepsin L precursor 0.0266 0.0882 0.2382
Echinococcus multilocularis calumenin 0.0132 0.0407 0.0407
Giardia lamblia Cathepsin B precursor 0.0266 0.0882 0.2382
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1089 0.3809 1
Toxoplasma gondii EF hand domain-containing protein 0.013 0.0398 0.0737
Echinococcus multilocularis programmed cell death protein 0.0133 0.0411 0.0411
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0081 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0225
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0015 0.0015
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0733 0.1545
Leishmania major cathepsin L-like protease 0.1089 0.3809 0.7046
Schistosoma mansoni microtubule-associated protein tau 0.1492 0.5238 0.5238
Leishmania major calpain protease-like protein 0.0234 0.0767 0.1419
Loa Loa (eye worm) cysteine protease 0.1089 0.3809 0.3809
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0062 0.0062
Echinococcus granulosus survival motor neuron protein 1 0.0258 0.0855 0.0855
Trypanosoma cruzi cysteine peptidase, putative 0.0334 0.1124 0.1124
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0021 0.0014 0.0014
Onchocerca volvulus 0.0081 0.0225 0.0416
Loa Loa (eye worm) hypothetical protein 0.0232 0.0762 0.0762
Echinococcus multilocularis chromatin regulatory protein sir2 0.0273 0.0908 0.0908
Trypanosoma brucei Calpain-like protein 1.2 0.0234 0.0767 0.1419
Onchocerca volvulus 0.0266 0.0882 0.1631
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.009 0.0256 0.054
Echinococcus multilocularis cathepsin L cysteine protease 0.1089 0.3809 0.3809
Trypanosoma brucei oligopeptidase b 0.0629 0.2173 0.4019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0267 0.0267
Onchocerca volvulus Peroxidasin homolog 0.0169 0.054 0.0998
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0093 0.0269 0.0269
Brugia malayi steroid hormone receptor 0.0022 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0266 0.0882 0.2315
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0266 0.0882 0.2382
Mycobacterium ulcerans putative transglutaminase-like protein 0.0248 0.082 0.3776
Onchocerca volvulus 0.1089 0.3809 0.7046
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0088 0.0088
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0091 0.0091
Trichomonas vaginalis calmodulin, putative 0.013 0.0398 0.1046
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0015 0.0015
Brugia malayi nuclear receptor NHR-88 0.0022 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0756 0.2623 0.2623
Plasmodium falciparum serine repeat antigen 7 0.0266 0.0882 0.2315
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0266 0.0882 0.2315
Toxoplasma gondii EFHC1, putative 0.013 0.0398 0.0737
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1352 0.4743 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0225
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0234 0.0767 0.2015
Plasmodium falciparum plasmepsin IX 0.0109 0.0324 0.0849
Mycobacterium ulcerans Sir2-like regulatory protein 0.007 0.0187 0.0861
Loa Loa (eye worm) hypothetical protein 0.1327 0.4654 0.4654
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0021 0.0014 0.0025
Trypanosoma brucei antigen, putative 0.0796 0.2765 0.5115
Echinococcus granulosus histone deacetylase 3 0.0087 0.0248 0.0248
Brugia malayi Papain family cysteine protease containing protein 0.06 0.2069 0.2069
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0302 0.1012 0.2733
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0028 0.0074
Trypanosoma brucei histone deacetylase, putative 0.0098 0.0286 0.053
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0043 0.0043
Onchocerca volvulus 0.0022 0.0015 0.0028
Giardia lamblia Cathepsin L precursor 0.0266 0.0882 0.2382

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 10.8 mg kg-1 In vivo anticonvulsant activity in male albino mice using the maximal electroshock (MES) test after intraperitoneal administration; value ranges from 9.1-12.1 ChEMBL. 12061883
ED50 (functional) = 10.8 mg kg-1 Effective dose required to prevent tonic extension of the hind limbs in mice in the maximal electroshock seizures (MES) test when administered intraperitoneally ChEMBL. 7799408
ED50 (functional) = 10.8 mg kg-1 In vivo anticonvulsant activity in male albino mice using the maximal electroshock (MES) test after intraperitoneal administration; value ranges from 9.1-12.1 ChEMBL. 12061883
ED50 (functional) = 10.8 mg kg-1 Effective dose required to prevent tonic extension of the hind limbs in mice in the maximal electroshock seizures (MES) test when administered intraperitoneally ChEMBL. 7799408
ED50 (functional) = 11 mg kg-1 Anticonvulsant activity in ip dosed albino CF-1 mouse assessed as protection against maximal electroshock-induced seizure after 0.5 hrs ChEMBL. 22546207
ED50 (functional) = 11 mg kg-1 Anticonvulsant activity in ip dosed CF1 mouse assessed as protection against maximal electroshock-induced seizure after 30 mins ChEMBL. 21639114
Log ED50 (functional) = 1.58 uM kg-1 In vivo anticonvulsant activity in male albino mice using the maximal electroshock seizure(MES) test upon intraperitoneal administration, expressed as logarithm of effective dose ChEMBL. 12061883
Log ED50 (functional) = 1.58 uM kg-1 In vivo anticonvulsant activity in male albino mice using the maximal electroshock seizure(MES) test upon intraperitoneal administration, expressed as logarithm of effective dose ChEMBL. 12061883
TD50 (functional) < 100 mg kg-1 Median neurologically impairing dose was determined in mice using the rotorod test ChEMBL. 7799408
TD50 (functional) < 100 mg kg-1 Median neurologically impairing dose was determined in mice using the rotorod test ChEMBL. 7799408

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.