Detailed information for compound 21388

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 347.823 | Formula: C15H14ClN5OS
  • H donors: 1 H acceptors: 2 LogP: 2.27 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1nc2c([nH]1)n(Cc1ccc(cc1)Cl)c1=NCCn1c2=O
  • InChi: 1S/C15H14ClN5OS/c1-23-14-18-11-12(19-14)21(8-9-2-4-10(16)5-3-9)15-17-6-7-20(15)13(11)22/h2-5H,6-8H2,1H3,(H,18,19)
  • InChiKey: YHVQYHRKVALFEL-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Peroxidasin 0.043 0.0757 0.0757
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0005 0.001
Entamoeba histolytica prolyl oligopeptidase family protein 0.0246 0.0406 0.1318
Loa Loa (eye worm) hypothetical protein 0.3423 0.6443 0.6443
Schistosoma mansoni cpg binding protein 0.0094 0.0117 0.0116
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0421 0.0739 0.1891
Mycobacterium tuberculosis Conserved protein 0.0073 0.0078 0.0225
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0233 0.0383 0.0382
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0215 0.0215
Leishmania major cathepsin L-like protease 0.1763 0.3288 0.8428
Schistosoma mansoni microtubule-associated protein tau 0.161 0.2998 0.2997
Echinococcus multilocularis tissue type plasminogen activator 0.0071 0.0073 0.0072
Brugia malayi Animal haem peroxidase family protein 0.043 0.0757 0.0757
Onchocerca volvulus 0.0046 0.0026 0.0045
Giardia lamblia Cathepsin B precursor 0.1933 0.3612 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Brugia malayi histone deacetylase 1 (HD1) 0.009 0.0109 0.0109
Echinococcus granulosus cathepsin b 0.5295 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Schistosoma mansoni ef hand domain family member A2 0.0233 0.0383 0.0382
Toxoplasma gondii histone deacetylase HDAC2 0.009 0.0109 0.0278
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.0069 0.0173
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0428 0.0751 0.075
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0045 0.0024 0.0024
Brugia malayi Blistered cuticle protein 3 0.043 0.0757 0.0757
Giardia lamblia Cathepsin B precursor 0.0428 0.0751 0.2078
Schistosoma mansoni hypothetical protein 0.0182 0.0285 0.0284
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0464 0.0821 0.0821
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0005 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0496 0.0882 0.0882
Brugia malayi mbt repeat family protein 0.0046 0.0027 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0078 0.0077
Loa Loa (eye worm) programmed cell death protein 6 0.0238 0.0391 0.0391
Toxoplasma gondii microneme protein MIC17B 0.0046 0.0026 0.0064
Brugia malayi Trypsin family protein 0.0189 0.0297 0.0297
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Toxoplasma gondii calmodulin CAM1 0.0238 0.0391 0.0999
Schistosoma mansoni hypothetical protein 0.0294 0.0498 0.0497
Mycobacterium tuberculosis Conserved hypothetical protein 0.0294 0.0498 0.1448
Echinococcus multilocularis neurogenic locus notch protein 0.0037 0.0008 0.0008
Trichomonas vaginalis calcium binding proteins, putative 0.0233 0.0383 0.1057
Leishmania major oligopeptidase b 0.0848 0.155 0.397
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0246 0.0406 0.1039
Brugia malayi MH2 domain containing protein 0.0131 0.0188 0.0188
Schistosoma mansoni hypothetical protein 0.0339 0.0582 0.0581
Schistosoma mansoni chromatin regulatory protein sir2 0.014 0.0206 0.0205
Trichomonas vaginalis calpain, putative 0.0421 0.0739 0.2043
Onchocerca volvulus 0.0189 0.0297 0.0648
Echinococcus granulosus protein jagged 1 0.0035 0.0006 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Loa Loa (eye worm) hypothetical protein 0.0428 0.0751 0.0751
Giardia lamblia Cathepsin L precursor 0.0428 0.0751 0.2078
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0078 0.0225
Echinococcus multilocularis calpain 7 (C02 family) 0.1439 0.2674 0.2673
Onchocerca volvulus 0.0189 0.0297 0.0648
Giardia lamblia High cysteine protein 0.0035 0.0006 0.0013
Schistosoma mansoni hypothetical protein 0.0189 0.0297 0.0297
Brugia malayi aspartic protease BmAsp-1, identical 0.0044 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0739 0.2043
Plasmodium falciparum metacaspase-like protein 0.0114 0.0155 0.05
Plasmodium falciparum plasmepsin X 0.0208 0.0334 0.1084
Echinococcus granulosus EF HAND 1 calcium binding site 0.0233 0.0383 0.0382
Brugia malayi Papain family cysteine protease containing protein 0.0428 0.0751 0.0751
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0233 0.0383 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.0428 0.0751 0.2078
Echinococcus multilocularis histone deacetylase 8 0.0043 0.0021 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0155 0.0426
Trypanosoma cruzi oligopeptidase b 0.0848 0.155 0.1549
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0044 0.0022 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0073 0.0073
Schistosoma mansoni cpg binding protein 0.0094 0.0117 0.0116
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0344 0.0593 0.1519
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0109 0.03
Schistosoma mansoni calpain-7 (C02 family) 0.1442 0.268 0.2679
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0365 0.0632 0.0631
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0428 0.0751 0.2078
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.4077 0.7686 0.7686
Trypanosoma cruzi calmodulin, putative 0.0233 0.0383 0.0382
Onchocerca volvulus 0.043 0.0757 0.1668
Schistosoma mansoni hypothetical protein 0.0114 0.0156 0.0155
Brugia malayi Cathepsin L-like precursor 0.1652 0.3077 0.3077
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0025 0.0025
Loa Loa (eye worm) peptidase C13 family protein 0.0149 0.0222 0.0222
Schistosoma mansoni neuronal calcium sensor 0.0233 0.0383 0.0382
Toxoplasma gondii microneme protein MIC17A 0.0046 0.0026 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0233 0.0383 0.1057
Plasmodium vivax hypothetical protein, conserved 0.0246 0.0406 0.1318
Trypanosoma cruzi metacaspase 5, putative 0.0114 0.0155 0.0154
Echinococcus granulosus Transglutaminase 0.0294 0.0498 0.0497
Loa Loa (eye worm) histone deacetylase 0.0101 0.013 0.013
Echinococcus multilocularis enteropeptidase 0.0189 0.0297 0.0297
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.013 0.013
Loa Loa (eye worm) proteasome subunit beta type 2 0.0045 0.0025 0.0025
Toxoplasma gondii prolyl endopeptidase 0.2085 0.3901 1
Plasmodium falciparum histone deacetylase, putative 0.0101 0.013 0.0421
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0924 0.1694 0.1694
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0039 0.0038
Trypanosoma brucei calpain, putative 0.0421 0.0739 0.1891
Trypanosoma brucei metacaspase MCA2 0.0114 0.0155 0.0394
Entamoeba histolytica cysteine proteinase, putative 0.0924 0.1694 0.5504
Brugia malayi Fli-1 protein 0.0213 0.0345 0.0345
Schistosoma mansoni notch 0.0035 0.0006 0.0005
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0109 0.03
Brugia malayi hypothetical protein 0.043 0.0757 0.0757
Echinococcus granulosus delta-like protein 1 0.0035 0.0006 0.0005
Toxoplasma gondii preprocathepsin c precursor, putative 0.0428 0.0751 0.1924
Trichomonas vaginalis calpain, putative 0.0421 0.0739 0.2043
Echinococcus multilocularis regulator of G protein signaling 0.0045 0.0025 0.0024
Onchocerca volvulus 0.1652 0.3077 0.6823
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.2673
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0246 0.0406 0.1039
Trypanosoma brucei cysteine peptidase, putative 0.0421 0.0739 0.1891
Loa Loa (eye worm) hypothetical protein 0.018 0.0282 0.0282
Plasmodium vivax proteasome subunit beta type-2, putative 0.0045 0.0025 0.0079
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Trypanosoma brucei prolyl oligopeptidase, putative 0.0848 0.155 0.397
Giardia lamblia Cysteine protease 0.0428 0.0751 0.2078
Onchocerca volvulus 0.0046 0.0026 0.0045
Mycobacterium ulcerans hypothetical protein 0.0294 0.0498 0.321
Echinococcus granulosus inhibitor of apoptosis protein 0.0189 0.0298 0.0297
Loa Loa (eye worm) hypothetical protein 0.0044 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) calpain D 0.0421 0.0739 0.0739
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0102 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Loa Loa (eye worm) hypothetical protein 0.0033 0.0002 0.0002
Leishmania major hypothetical protein, unknown function 0.0421 0.0739 0.1891
Brugia malayi Ets-domain containing protein 0.007 0.0073 0.0073
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1439 0.2674 0.6853
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0025 0.0024
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0005 0.0004
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0428 0.0751 0.2078
Echinococcus multilocularis cathepsin L 0.0924 0.1694 0.1694
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0039 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0078 0.0251
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0005 0.0009
Giardia lamblia Cathepsin L precursor 0.0428 0.0751 0.2078
Echinococcus multilocularis calpain 5 0.1439 0.2674 0.2673
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0071 0.0074 0.0073
Plasmodium falciparum serine repeat antigen 6 0.0428 0.0751 0.2439
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0428 0.0751 0.2439
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Brugia malayi notch-like transmembrane receptor 0.0035 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0233 0.0383 0.0382
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0206 0.0567
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0848 0.155 0.397
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0114 0.0155 0.0154
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.0751 0.075
Trichomonas vaginalis set domain proteins, putative 0.0528 0.0942 0.2606
Echinococcus multilocularis cpg binding protein 0.0094 0.0117 0.0116
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.014 0.0206 0.0567
Brugia malayi Papain family cysteine protease containing protein 0.0428 0.0751 0.0751
Trypanosoma brucei calpain-like protein, putative 0.1439 0.2674 0.6853
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0044 0.0022 0.0021
Trypanosoma cruzi cysteine peptidase, putative 0.1763 0.3288 0.3288
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0005
Entamoeba histolytica glycogen phosphorylase, putative 0.0121 0.0169 0.0548
Trypanosoma cruzi cysteine proteinase, putative 0.0924 0.1694 0.1694
Trichomonas vaginalis calmodulin, putative 0.0238 0.0391 0.1079
Schistosoma mansoni histone deacetylase hda2 0.0107 0.0142 0.0141
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Trypanosoma brucei histone deacetylase, putative 0.0101 0.013 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0025 0.0066
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0233 0.0383 0.0978
Echinococcus granulosus geminin 0.0339 0.0582 0.0581
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0739 0.0738
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0428 0.0751 0.2439
Loa Loa (eye worm) hypothetical protein 0.0246 0.0406 0.0406
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0188 0.0188
Trichomonas vaginalis centrin, putative 0.0233 0.0383 0.1057
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1652 0.3077 0.3077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Brugia malayi Cathepsin L-like precursor 0.1652 0.3077 0.3077
Schistosoma mansoni hypothetical protein 0.0071 0.0073 0.0072
Loa Loa (eye worm) calpain family protein 1 0.3843 0.7243 0.7243
Echinococcus multilocularis calmodulin 0.0233 0.0383 0.0382
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.2673
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0078 0.0214
Echinococcus multilocularis neuronal calcium sensor 0.0233 0.0383 0.0382
Schistosoma mansoni calmodulin related calcium binding protein 0.0233 0.0383 0.0382
Giardia lamblia Transglutaminase/protease, putative 0.0294 0.0498 0.1377
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0027 0.0026
Brugia malayi Cathepsin L-like precursor 0.0496 0.0882 0.0882
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0025 0.0024
Toxoplasma gondii centrin, putative 0.0233 0.0383 0.0978
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0068 0.0069 0.0068
Loa Loa (eye worm) hypothetical protein 0.0428 0.0751 0.0751
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.006 0.0059
Toxoplasma gondii hypothetical protein 0.0046 0.0026 0.0064
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0027 0.0026
Giardia lamblia Cathepsin L-like protease 0.0428 0.0751 0.2078
Entamoeba histolytica hypothetical protein 0.0045 0.0025 0.0078
Trypanosoma cruzi calmodulin, putative 0.0233 0.0383 0.0382
Plasmodium vivax vivapain-2 0.1652 0.3077 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0428 0.0751 0.2078
Onchocerca volvulus 0.0233 0.0383 0.0837
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.0069 0.0068
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0246 0.0406 0.1122
Schistosoma mansoni inhibitor of apoptosis protein 0.0189 0.0298 0.0297
Plasmodium falciparum cysteine repeat modular protein 1 0.0071 0.0073 0.0235
Onchocerca volvulus Cell death protein 3 homolog 0.0295 0.05 0.1099
Trypanosoma cruzi major cysteine proteinase, putative 0.0539 0.0962 0.0962
Echinococcus multilocularis tumor protein p63 0.0731 0.1327 0.1326
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.001 0.0009
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0157 0.0237 0.0236
Brugia malayi Trypsin family protein 0.0189 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0005
Onchocerca volvulus 0.0046 0.0026 0.0045
Toxoplasma gondii troponin c, isotype gamma, putative 0.0233 0.0383 0.0978
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0051 0.0051
Plasmodium falciparum serine repeat antigen 8 0.0428 0.0751 0.2439
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.001 0.001
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0233 0.0383 0.1057
Plasmodium vivax unspecified product 0.0428 0.0751 0.2439
Loa Loa (eye worm) trypsin family protein 0.0189 0.0297 0.0297
Onchocerca volvulus 0.0046 0.0026 0.0045
Brugia malayi Cytochrome P450 family protein 0.0037 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0073 0.0078 0.0078
Echinococcus granulosus Glycosyl transferase family 35 0.0121 0.0169 0.0169
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0071 0.0073 0.0235
Loa Loa (eye worm) prolyl oligopeptidase 0.0246 0.0406 0.0406
Echinococcus multilocularis Mastin 0.0189 0.0297 0.0297
Trypanosoma cruzi metacaspase, putative 0.0114 0.0155 0.0154
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0428 0.0751 0.2078
Plasmodium vivax histone deacetylase 2, putative 0.0101 0.013 0.0421
Onchocerca volvulus Cathepsin F homolog 0.1652 0.3077 0.6823
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0189 0.0297 0.0297
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.2673
Echinococcus multilocularis histone deacetylase 1 0.009 0.0109 0.0108
Mycobacterium leprae Conserved hypothetical protein 0.0294 0.0498 0.2853
Echinococcus multilocularis cysteine protease 0.1652 0.3077 0.3077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0008
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0157 0.0237 0.0767
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.2673
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0039 0.0038
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0046 0.0026 0.0026
Echinococcus granulosus histone deacetylase 6 0.0101 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0008
Echinococcus multilocularis geminin 0.0339 0.0582 0.0581
Echinococcus granulosus proteasome prosome macropain 0.0157 0.0237 0.0236
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0157 0.0237 0.0237
Trypanosoma brucei metacaspase 0.0114 0.0155 0.0394
Plasmodium falciparum plasmepsin IV 0.0044 0.0022 0.007
Trichomonas vaginalis calmodulin, putative 0.0233 0.0383 0.1057
Brugia malayi Cathepsin L-like precursor 0.1652 0.3077 0.3077
Echinococcus granulosus caspase 0.0327 0.0561 0.056
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0233 0.0383 0.1241
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1439 0.2674 0.2673
Echinococcus multilocularis neural cadherin 0.0035 0.0006 0.0005
Giardia lamblia Proteasome subunit beta type 2 0.0045 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Trichomonas vaginalis calmodulin, putative 0.0233 0.0383 0.1057
Echinococcus granulosus glycogen phosphorylase 0.0121 0.0169 0.0169
Giardia lamblia Cathepsin L precursor 0.0428 0.0751 0.2078
Onchocerca volvulus Peroxidase homolog 0.043 0.0757 0.1668
Loa Loa (eye worm) animal heme peroxidase 0.043 0.0757 0.0757
Loa Loa (eye worm) hypothetical protein 0.0099 0.0126 0.0126
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0428 0.0751 0.2439
Brugia malayi EGF-like domain containing protein 0.0035 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Brugia malayi calpain 5 0.0421 0.0739 0.0739
Loa Loa (eye worm) glycogen phosphorylase 0.0121 0.0169 0.0169
Loa Loa (eye worm) CYP4Cod1 0.0037 0.001 0.001
Entamoeba histolytica prolyl oligopeptidase family protein 0.0246 0.0406 0.1318
Brugia malayi hypothetical protein 0.0182 0.0285 0.0285
Schistosoma mansoni hypothetical protein 0.0189 0.0298 0.0297
Onchocerca volvulus 0.0044 0.0022 0.0037
Brugia malayi Histone deacetylase family protein 0.0101 0.013 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1155 0.2134 0.5908
Plasmodium falciparum plasmepsin VII 0.0044 0.0022 0.007
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0078 0.0078
Leishmania major hypothetical protein, conserved 0.0238 0.0391 0.0999
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5295 1 1
Trichomonas vaginalis calmodulin, putative 0.0241 0.0397 0.1096
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0206 0.0567
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0078 0.0225
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.007 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0008
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0428 0.0751 0.2439
Brugia malayi transcriptional regulator, Sir2 family protein 0.0033 0.0001 0.0001
Plasmodium vivax proteasome subunit beta type-1, putative 0.007 0.0072 0.023
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) hypothetical protein 0.0189 0.0297 0.0297
Schistosoma mansoni z-protein (S1r protein) 0.0045 0.0025 0.0024
Trichomonas vaginalis calcineurin B subunit, putative 0.0233 0.0383 0.1057
Plasmodium falciparum serine repeat antigen 4 0.0428 0.0751 0.2439
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Brugia malayi Kringle domain containing protein 0.0071 0.0073 0.0073
Brugia malayi EF hand family protein 0.0233 0.0383 0.0383
Trypanosoma cruzi I/6 autoantigen, putative 0.0233 0.0383 0.0382
Onchocerca volvulus 0.0189 0.0297 0.0648
Trypanosoma cruzi kinesin, putative 0.1018 0.1874 0.1874
Trichomonas vaginalis calcium binding protein, putative 0.0241 0.0397 0.1096
Loa Loa (eye worm) hypothetical protein 0.0073 0.0078 0.0078
Onchocerca volvulus Dual oxidase homolog 0.043 0.0757 0.1668
Schistosoma mansoni chromatin regulatory protein sir2 0.0127 0.018 0.0179
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0189 0.0297 0.0297
Toxoplasma gondii hypothetical protein 0.0421 0.0739 0.1891
Loa Loa (eye worm) MBCTL1 0.0053 0.0039 0.0039
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0114 0.0155 0.0155
Trypanosoma cruzi kinesin, putative 0.1018 0.1874 0.1874
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0027 0.0027
Onchocerca volvulus 0.1652 0.3077 0.6823
Leishmania major proteasome beta 2 subunit, putative 0.0045 0.0025 0.0062
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0025 0.0025
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0008 0.0008
Echinococcus granulosus neuronal calcium sensor 0.0233 0.0383 0.0382
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0246 0.0406 0.1122
Loa Loa (eye worm) prolyl oligopeptidase 0.0599 0.1077 0.1077
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0051 0.005
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1839 0.3434 1
Onchocerca volvulus Deterin homolog 0.0189 0.0298 0.0649
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0739 0.2043
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0025 0.0024
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1652 0.3077 0.3077
Leishmania major cathepsin L-like protease 0.1652 0.3077 0.7887
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Onchocerca volvulus 0.0046 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0428 0.0751 0.0751
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0222 0.0221
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1155 0.2134 0.5908
Trichomonas vaginalis calmodulin, putative 0.0233 0.0383 0.1057
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1652 0.3077 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0078 0.0499
Entamoeba histolytica cysteine proteinase, putative 0.1652 0.3077 1
Plasmodium falciparum calpain 0.0421 0.0739 0.2398
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0039 0.0122
Brugia malayi Animal haem peroxidase family protein 0.043 0.0757 0.0757
Giardia lamblia Alanyl dipeptidyl peptidase 0.0246 0.0406 0.1122
Echinococcus granulosus fibropellin Ia 0.0035 0.0006 0.0005
Brugia malayi PXA domain containing protein 0.0045 0.0025 0.0025
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0021 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) histone deacetylase 3 0.009 0.0109 0.0109
Trypanosoma cruzi metacaspase, putative 0.0114 0.0155 0.0154
Trypanosoma brucei antigen, putative 0.1439 0.2674 0.6853
Echinococcus granulosus cathepsin L 0.0428 0.0751 0.075
Brugia malayi Delta serrate ligand family protein 0.0035 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0293 0.0495 0.0494
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0044 0.0022 0.006
Echinococcus granulosus Tolloid protein 1 0.0045 0.0024 0.0023
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1439 0.2674 0.2673
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0127 0.018 0.0179
Toxoplasma gondii PAN/Apple domain-containing protein 0.0046 0.0026 0.0064
Trichomonas vaginalis calmodulin, putative 0.0233 0.0383 0.1057
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0039 0.0039
Loa Loa (eye worm) PXA domain-containing protein 0.0045 0.0025 0.0025
Brugia malayi GPI-anchor transamidase 0.0035 0.0005 0.0005
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0078 0.0225
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0233 0.0383 0.0382
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0194 0.0308 0.0307
Plasmodium vivax proteasome subunit beta type-5, putative 0.0157 0.0237 0.0767
Trypanosoma cruzi 20S proteasome subunit 0.0045 0.0025 0.0024
Mycobacterium ulcerans hypothetical protein 0.0189 0.0297 0.1915
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0428 0.0751 0.075
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.1652 0.3077 0.3077
Giardia lamblia Encystation-specific protease 0.0428 0.0751 0.2078
Schistosoma mansoni caspase-7 (C14 family) 0.0327 0.0561 0.056
Brugia malayi Calcium binding EGF domain containing protein 0.004 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0045 0.0025 0.0066
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Loa Loa (eye worm) hypothetical protein 0.0496 0.0882 0.0882
Onchocerca volvulus 0.0073 0.0078 0.0161
Onchocerca volvulus 0.0528 0.0942 0.2079
Loa Loa (eye worm) hypothetical protein 0.014 0.0206 0.0206
Entamoeba histolytica grainin, putative 0.0238 0.0391 0.1266
Toxoplasma gondii cathepsin CPC1 0.0428 0.0751 0.1924
Brugia malayi Papain family cysteine protease containing protein 0.0428 0.0751 0.0751
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0421 0.0739 0.2043
Echinococcus multilocularis proteasome (prosome, macropain) 0.0157 0.0237 0.0236
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0005 0.0012
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0005 0.0009
Echinococcus multilocularis centrin 2 0.0233 0.0383 0.0382
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0189 0.0297 0.0297
Echinococcus multilocularis calpain family protein 1, d 0.2825 0.5307 0.5307
Schistosoma mansoni histone deacetylase 4 5 0.0101 0.013 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0428 0.0751 0.2078
Trypanosoma cruzi centrin-3 0.0241 0.0397 0.0396
Brugia malayi Trypsin family protein 0.0189 0.0297 0.0297
Trypanosoma cruzi cruzipain precursor, putative 0.1763 0.3288 0.3288
Mycobacterium tuberculosis Probable peptidase 0.0848 0.155 0.4511
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0428 0.0751 0.2078
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5295 1 1
Echinococcus granulosus cysteine protease 0.0924 0.1694 0.1694
Loa Loa (eye worm) hypothetical protein 0.0189 0.0298 0.0298
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0026 0.0064
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Echinococcus multilocularis calmodulin 0.0233 0.0383 0.0382
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0039 0.0122
Loa Loa (eye worm) hypothetical protein 0.0053 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1933 0.3612 1
Loa Loa (eye worm) hypothetical protein 0.0189 0.0297 0.0297
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0194 0.0308 0.0307
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0127 0.018 0.0179
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0082 0.0082
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.0037 0.0036
Schistosoma mansoni ap endonuclease 0.0059 0.0051 0.005
Schistosoma mansoni notch 0.0035 0.0006 0.0005
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0072 0.0196
Brugia malayi prolyl oligopeptidase family protein 0.0246 0.0406 0.0406
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0739 0.1891
Schistosoma mansoni cathepsin C 0.0428 0.0751 0.075
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0739 0.0738
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Leishmania major histone deacetylase, putative 0.0101 0.013 0.0332
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1439 0.2674 0.2673
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0102 0.0133 0.0385
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0073 0.0072
Brugia malayi mbt repeat family protein 0.0046 0.0027 0.0027
Echinococcus multilocularis neurogenic locus protein delta 0.0035 0.0006 0.0005
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0027 0.0047
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0026 0.0064
Schistosoma mansoni calmodulin 0.0233 0.0383 0.0382
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0428 0.0751 0.2439
Loa Loa (eye worm) hypothetical protein 0.2085 0.3901 0.3901
Leishmania major silent information regulator 2, putative 0.0127 0.018 0.0459
Loa Loa (eye worm) hypothetical protein 0.0044 0.0022 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Brugia malayi cathepsin L-like cysteine proteinase 0.0428 0.0751 0.0751
Echinococcus granulosus calpain A 0.4081 0.7694 0.7694
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0021 0.002
Brugia malayi Muscle positioning protein 4 0.0037 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Toxoplasma gondii exonuclease III APE 0.0059 0.0051 0.0129
Brugia malayi cathepsin L precursor 0.0428 0.0751 0.0751
Loa Loa (eye worm) hypothetical protein 0.1155 0.2134 0.2134
Brugia malayi prolyl oligopeptidase family protein 0.0344 0.0593 0.0593
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0421 0.0739 0.0738
Plasmodium falciparum histone deacetylase 1 0.009 0.0109 0.0353
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0051 0.0164
Plasmodium vivax histone deacetylase, putative 0.0101 0.013 0.0421
Onchocerca volvulus 0.0182 0.0285 0.062
Trypanosoma cruzi prolyl endopeptidase 0.2085 0.3901 0.3901
Giardia lamblia Cathepsin B precursor 0.0428 0.0751 0.2078
Echinococcus multilocularis cathepsin b 0.5295 1 1
Schistosoma mansoni histone deacetylase 0.009 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Leishmania major metacaspase, putative 0.0114 0.0155 0.0394
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0025 0.0024
Echinococcus granulosus histone lysine methyltransferase setb 0.0068 0.0069 0.0068
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0005 0.0004
Echinococcus multilocularis acylamino acid releasing enzyme 0.0246 0.0406 0.0405
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0215 0.0215
Brugia malayi Pre-SET motif family protein 0.0068 0.0069 0.0069
Leishmania major calmodulin-like protein 0.0233 0.0383 0.0978
Echinococcus granulosus calpain 5 0.1439 0.2674 0.2673
Trypanosoma brucei Metacaspase-4 0.0114 0.0155 0.0394
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0064 0.006 0.006
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1652 0.3077 0.3077
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0428 0.0751 0.2078
Trypanosoma cruzi I/6 autoantigen, putative 0.0233 0.0383 0.0382
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0051 0.0129
Onchocerca volvulus 0.0238 0.0391 0.0855
Loa Loa (eye worm) hypothetical protein 0.0102 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0365 0.0632 0.0632
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0026 0.0064
Toxoplasma gondii calcium-dependent protein kinase 0.0238 0.0391 0.0999
Leishmania major phospholipase c-like protein 0.0233 0.0383 0.0978
Schistosoma mansoni cathepsin s 0.0496 0.0882 0.0881
Brugia malayi EGF-like domain containing protein 0.0035 0.0006 0.0006
Brugia malayi EGF-like domain containing protein 0.0035 0.0006 0.0006
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0026 0.0064
Loa Loa (eye worm) hypothetical protein 0.0295 0.05 0.05
Trypanosoma cruzi cysteine proteinase, putative 0.0924 0.1694 0.1694
Brugia malayi Cathepsin L-like precursor 0.1155 0.2134 0.2134
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0848 0.155 0.1549
Trypanosoma cruzi Aph-1 protein, putative 0.0109 0.0146 0.0145
Echinococcus granulosus cathepsin l1 0.1155 0.2134 0.2134
Echinococcus multilocularis transmembrane protease serine 3 0.0189 0.0297 0.0297
Brugia malayi histone deacetylase 11 0.0043 0.0021 0.0021
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0428 0.0751 0.075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0294 0.0498 0.1448
Trypanosoma cruzi centrin, putative 0.0241 0.0397 0.0396
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0157 0.0237 0.0605
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0157 0.0237 0.0654
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0305 0.0304
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0924 0.1694 0.4341
Loa Loa (eye worm) histone deacetylase 7A 0.0101 0.013 0.013
Trichomonas vaginalis calcium binding protein, putative 0.0233 0.0383 0.1057
Entamoeba histolytica calpain large subunit domain III containing protein 0.1018 0.1874 0.609
Onchocerca volvulus 0.1652 0.3077 0.6823
Loa Loa (eye worm) hypothetical protein 0.0182 0.0285 0.0285
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0045 0.0025 0.0024
Loa Loa (eye worm) transcriptional regulator 0.0033 0.0001 0.0001
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0021 0.002
Trypanosoma brucei calpain-like protein, putative 0.1439 0.2674 0.6853
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Schistosoma mansoni glycogen phosphorylase 0.0121 0.0169 0.0169
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0233 0.0383 0.0978
Trichomonas vaginalis calmodulin-2, putative 0.0233 0.0383 0.1057
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0045 0.0025 0.0024
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0344 0.0593 0.1519
Loa Loa (eye worm) hypothetical protein 0.0189 0.0297 0.0297
Loa Loa (eye worm) blistered cuticle protein 3 0.043 0.0757 0.0757
Trypanosoma cruzi calmodulin, putative 0.0233 0.0383 0.0382
Entamoeba histolytica glycogenphosphorylase, putative 0.0052 0.0039 0.0122
Trypanosoma cruzi centrin, putative 0.0241 0.0397 0.0396
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0051 0.005
Schistosoma mansoni slit 0.0035 0.0006 0.0005
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Echinococcus granulosus cathepsin l cysteine peptidase 0.1652 0.3077 0.3077
Schistosoma mansoni notch 0.0035 0.0006 0.0005
Brugia malayi cathepsin F-like cysteine proteinase 0.0428 0.0751 0.0751
Echinococcus granulosus prolyl endopeptidase 0.2085 0.3901 0.3901
Echinococcus granulosus caspase 8 0.0114 0.0155 0.0154
Brugia malayi carbohydrate phosphorylase 0.0121 0.0169 0.0169
Echinococcus multilocularis glycoprotein Antigen 5 0.0189 0.0297 0.0297
Giardia lamblia Cathepsin L precursor 0.0428 0.0751 0.2078
Loa Loa (eye worm) hypothetical protein 0.0077 0.0086 0.0086
Brugia malayi Thioredoxin family protein 0.0294 0.0498 0.0498
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0078 0.0077
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0157 0.0237 0.0236
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0025 0.0024
Brugia malayi Cathepsin L-like precursor 0.1652 0.3077 0.3077
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0186 0.0293 0.0293
Trypanosoma brucei prolyl endopeptidase 0.2085 0.3901 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0428 0.0751 0.2078
Brugia malayi Proteasome A-type and B-type family protein 0.0157 0.0237 0.0237
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0051 0.014
Plasmodium falciparum plasmepsin I 0.0044 0.0022 0.007
Echinococcus multilocularis cathepsin b 0.5295 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0016
Entamoeba histolytica calpain family cysteine protease, putative 0.0421 0.0739 0.2398
Loa Loa (eye worm) cysteine protease 0.1652 0.3077 0.3077
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1439 0.2674 0.2673
Toxoplasma gondii centrin 0.0233 0.0383 0.0978
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Trypanosoma cruzi cysteine peptidase, putative 0.0924 0.1694 0.1694
Onchocerca volvulus 0.1652 0.3077 0.6823
Trypanosoma brucei caltractin, putative 0.0241 0.0397 0.1014
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0078 0.0214
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Trichomonas vaginalis calcium binding protein, putative 0.0233 0.0383 0.1057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0428 0.0751 0.2078
Echinococcus granulosus microtubule associated protein 2 0.161 0.2998 0.2997
Echinococcus granulosus neurogenic locus notch protein 4 0.0035 0.0006 0.0005
Schistosoma mansoni neuronal calcium sensor 0.0233 0.0383 0.0382
Leishmania major calmodulin-like protein 0.0233 0.0383 0.0978
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0406 0.1122
Schistosoma mansoni notch 0.0035 0.0006 0.0005
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0246 0.0406 0.0405
Onchocerca volvulus 0.1652 0.3077 0.6823
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2085 0.3901 0.3901
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Plasmodium vivax metacaspase 1, putative 0.0114 0.0155 0.05
Echinococcus multilocularis histone deacetylase 6 0.0107 0.0142 0.0141
Trypanosoma cruzi metacaspase, putative 0.0114 0.0155 0.0154
Leishmania major hypothetical protein, conserved 0.0233 0.0383 0.0978
Schistosoma mansoni centrin 0.0233 0.0383 0.0382
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0046 0.0026 0.0064
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0082
Schistosoma mansoni Mername-AA248 (C02 family) 0.1439 0.2674 0.2673
Echinococcus multilocularis Transglutaminase 0.0294 0.0498 0.0497
Entamoeba histolytica grainin 2 0.0241 0.0397 0.1286
Trypanosoma brucei centrin-3 0.0241 0.0397 0.1014
Brugia malayi PXA domain containing protein 0.0045 0.0025 0.0025
Leishmania major calmodulin, putative 0.0233 0.0383 0.0978
Entamoeba histolytica calcium binding family protein 0.0233 0.0383 0.1241
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0428 0.0751 0.2078
Echinococcus multilocularis calcium uptake protein 1 0.0238 0.0391 0.039
Entamoeba histolytica glycogen phosphorylase, putative 0.0121 0.0169 0.0548
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0025 0.0024
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0005 0.0009
Brugia malayi Papain family cysteine protease containing protein 0.0924 0.1694 0.1694
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0157 0.0237 0.1078
Echinococcus multilocularis calpain A 0.4081 0.7694 0.7694
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Trypanosoma cruzi histone deacetylase 1, putative 0.009 0.0109 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0025 0.0066
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0025 0.0024
Echinococcus granulosus centrin 2 0.0233 0.0383 0.0382
Chlamydia trachomatis glycogen phosphorylase 0.0121 0.0169 0.5
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0233 0.0383 0.0382
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0025
Echinococcus granulosus proteasome prosome macropain subunit beta 0.007 0.0072 0.0071
Onchocerca volvulus Cathepsin L homolog 0.1652 0.3077 0.6823
Brugia malayi calpain family protein 1 0.3843 0.7243 0.7243
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0026 0.0026
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0039 0.0038
Schistosoma mansoni hypothetical protein 0.0233 0.0383 0.0382
Loa Loa (eye worm) hypothetical protein 0.1155 0.2134 0.2134
Echinococcus granulosus cathepsin L cysteine proteinase 0.1652 0.3077 0.3077
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0025
Brugia malayi cathepsin L-like precursor 0.1155 0.2134 0.2134
Mycobacterium tuberculosis Conserved protein 0.0073 0.0078 0.0225
Brugia malayi transcriptional regulator, Sir2 family protein 0.0033 0.0001 0.0001
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0428 0.0751 0.2439
Echinococcus granulosus protein jagged 1 0.0035 0.0006 0.0005
Leishmania major calpain family cysteine protease-like protein 0.0421 0.0739 0.1891
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0025 0.0024
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0421 0.0738 0.0737
Plasmodium vivax SET domain protein, putative 0.0068 0.0069 0.022
Leishmania major protein kinase, putative 0.0233 0.0383 0.0978
Echinococcus granulosus calpain A 0.1439 0.2674 0.2673
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0071 0.0074 0.0186
Loa Loa (eye worm) hypothetical protein 0.0102 0.0133 0.0133
Brugia malayi Cathepsin L-like cysteine proteinase 0.1155 0.2134 0.2134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0082 0.0082
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0246 0.0406 0.0405
Onchocerca volvulus 0.0046 0.0026 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Onchocerca volvulus 0.043 0.0757 0.1668
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Toxoplasma gondii microneme protein MIC17C 0.0046 0.0026 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0025 0.0066
Mycobacterium ulcerans hypothetical protein 0.0073 0.0078 0.0499
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0005 0.001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0051 0.0164
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0008 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0496 0.0882 0.0881
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0344 0.0593 0.1519
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0127 0.018 0.0496
Loa Loa (eye worm) histone deacetylase 11 0.0043 0.0021 0.0021
Brugia malayi proteasome subunit beta type 2 0.0045 0.0025 0.0025
Giardia lamblia Cathepsin B precursor 0.0428 0.0751 0.2078
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0114 0.0155 0.0394
Schistosoma mansoni hypothetical protein 0.0033 0.0002 0.0001
Echinococcus granulosus enteropeptidase 0.0189 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0102 0.0133 0.0133
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0468 0.0829 0.2412
Loa Loa (eye worm) cathepsin B 0.1933 0.3612 0.3612
Echinococcus granulosus neurogenic locus protein delta 0.0035 0.0006 0.0005
Brugia malayi EGF-like domain containing protein 0.0035 0.0006 0.0006
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0027 0.0026
Loa Loa (eye worm) aspartyl protease 6 0.0044 0.0022 0.0022
Trypanosoma brucei Calpain-like protein CALP1.3 0.0421 0.0739 0.1891
Toxoplasma gondii aspartyl protease 0.0044 0.0022 0.0055
Echinococcus multilocularis caspase 3 0.0214 0.0345 0.0344
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Mycobacterium tuberculosis Conserved protein 0.0294 0.0498 0.1448
Mycobacterium ulcerans zinc metalloprotease 0.0102 0.0133 0.0853
Trypanosoma brucei metacaspase MCA3 0.0114 0.0155 0.0394
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0127 0.018 0.0179
Echinococcus multilocularis histone deacetylase 6 0.0101 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0051 0.0035 0.0035
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0421 0.0739 0.1891
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.001 0.0009
Plasmodium vivax aspartyl protease, putative 0.0208 0.0334 0.1084
Schistosoma mansoni neuronal calcium sensor 0.0233 0.0383 0.0382
Schistosoma mansoni gabp alpha 0.007 0.0073 0.0072
Plasmodium vivax calpain, putative 0.1439 0.2674 0.8689
Brugia malayi Trypsin-like protease protein 5 0.0189 0.0297 0.0297
Loa Loa (eye worm) ctsf protein 0.1652 0.3077 0.3077
Giardia lamblia Hypothetical protein 0.0428 0.0751 0.2078
Trypanosoma brucei cysteine peptidase C (CPC) 0.1933 0.3612 0.9257
Entamoeba histolytica calmodulin, putative 0.0233 0.0383 0.1241
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0739 0.0738
Onchocerca volvulus 0.0088 0.0107 0.0225
Giardia lamblia Hypothetical protein 0.0238 0.0391 0.1079
Schistosoma mansoni chromatin regulatory protein sir2 0.0127 0.018 0.0179
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0078 0.0225
Loa Loa (eye worm) sirtuin 4 0.0033 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0086 0.0086
Schistosoma mansoni cathepsin F (C01 family) 0.1652 0.3077 0.3077
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0071 0.0074 0.0211
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.0109 0.03
Plasmodium vivax plasmepsin IV, putative 0.0044 0.0022 0.007
Echinococcus granulosus calpain 7 C02 family 0.1439 0.2674 0.2673
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0078 0.0225
Brugia malayi Eukaryotic aspartyl protease family protein 0.0044 0.0022 0.0022
Schistosoma mansoni ap endonuclease 0.0059 0.0051 0.005
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0344 0.0593 0.0593
Entamoeba histolytica cysteine protease, putative 0.0428 0.0751 0.2439
Toxoplasma gondii aspartyl protease ASP3 0.0208 0.0334 0.0855
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0078 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0155 0.0426
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.0751 0.075
Trypanosoma brucei cytochrome P450, putative 0.0037 0.001 0.0023
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0025 0.0067
Plasmodium falciparum metacaspase 1 0.0114 0.0155 0.05
Echinococcus granulosus cathepsin l1 0.1652 0.3077 0.3077
Mycobacterium leprae probable zinc metalloprotease 0.0102 0.0133 0.0373
Echinococcus multilocularis gamma secretase subunit aph 1 0.028 0.047 0.0469
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1652 0.3077 1
Trypanosoma brucei calpain, putative 0.0421 0.0739 0.1891
Echinococcus granulosus calmodulin 0.0233 0.0383 0.0382
Loa Loa (eye worm) hypothetical protein 0.0108 0.0144 0.0144
Echinococcus multilocularis Regulator of G protein signaling 20 0.0045 0.0025 0.0024
Schistosoma mansoni hypothetical protein 0.0339 0.0582 0.0581
Echinococcus granulosus cpg binding protein 0.0094 0.0117 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0428 0.0751 0.2078
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0739 0.2043
Plasmodium falciparum plasmepsin III 0.0044 0.0022 0.007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.0751 0.075
Onchocerca volvulus 0.1652 0.3077 0.6823
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0206 0.0567
Echinococcus granulosus neurogenic locus notch protein 0.0035 0.0006 0.0005
Brugia malayi transcriptional regulator, Sir2 family protein 0.0127 0.018 0.018
Schistosoma mansoni calpain C (C02 family) 0.1439 0.2674 0.2673
Echinococcus granulosus acylamino acid releasing enzyme 0.0246 0.0406 0.0405
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0078 0.0077
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0189 0.0298 0.0297
Echinococcus granulosus endothelin converting enzyme 1 0.0102 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0046 0.0026 0.0026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Loa Loa (eye worm) hypothetical protein 0.0046 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0005
Plasmodium vivax serine-repeat antigen (SERA) 0.0428 0.0751 0.2439
Entamoeba histolytica hypothetical protein 0.0045 0.0025 0.0078
Entamoeba histolytica hypothetical protein, conserved 0.0246 0.0406 0.1318
Echinococcus multilocularis EF hand domain containing family member A2 0.0238 0.0391 0.039
Brugia malayi Cathepsin L-like precursor 0.1652 0.3077 0.3077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0069 0.0068
Echinococcus multilocularis programmed cell death protein 0.0241 0.0397 0.0396
Loa Loa (eye worm) hypothetical protein 0.0233 0.0383 0.0383
Entamoeba histolytica proteasome subunit beta type 1, putative 0.007 0.0072 0.023
Trypanosoma brucei metacaspase 5, putative 0.0114 0.0155 0.0394
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0025
Echinococcus multilocularis protein jagged 1 0.0035 0.0006 0.0005
Entamoeba histolytica cysteine protease, putative 0.1652 0.3077 1
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2085 0.3901 1
Entamoeba histolytica cysteine protease, putative 0.0428 0.0751 0.2439
Echinococcus granulosus histone deacetylase 7 0.0101 0.013 0.013
Leishmania major cathepsin L-like protease 0.1763 0.3288 0.8428
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0025 0.0024
Schistosoma mansoni mitochondrial solute carrier 0.0233 0.0383 0.0382
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0025 0.0024
Leishmania major centrin, putative,caltractin, putative 0.0233 0.0383 0.0978
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.5295 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Onchocerca volvulus 0.0068 0.0069 0.014
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0073 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0025 0.0066
Echinococcus granulosus calpain 0.1439 0.2674 0.2673
Plasmodium falciparum proteasome subunit beta type-5 0.0157 0.0237 0.0767
Toxoplasma gondii aldehyde dehydrogenase 0.0071 0.0074 0.0186
Echinococcus granulosus Dipeptidyl peptidase 9 0.0344 0.0593 0.0593
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0428 0.0751 0.2439
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0206 0.0567
Trypanosoma cruzi major cysteine proteinase, putative 0.0428 0.0751 0.075
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1652 0.3077 0.3077
Echinococcus multilocularis cathepsin L cysteine protease 0.1652 0.3077 0.3077
Schistosoma mansoni glycogen phosphorylase 0.0121 0.0169 0.0169
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0051 0.0164
Echinococcus granulosus expressed protein 0.0881 0.1613 0.1612
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Echinococcus granulosus glycoprotein Antigen 5 0.0189 0.0297 0.0297
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0739 0.0738
Trypanosoma cruzi Aph-1 protein, putative 0.0109 0.0146 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0428 0.0751 0.2078
Echinococcus granulosus calbindin 32 0.0238 0.0391 0.039
Loa Loa (eye worm) hypothetical protein 0.0046 0.0026 0.0026
Giardia lamblia Cathepsin L precursor 0.0428 0.0751 0.2078
Schistosoma mansoni caspase-7 (C14 family) 0.0295 0.05 0.05
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0428 0.0751 0.2078
Toxoplasma gondii EF hand domain-containing protein 0.0233 0.0383 0.0978
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0189 0.0298 0.0298
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0045 0.0024 0.0023
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1266 0.2345 0.2345
Echinococcus multilocularis calbindin 32 0.0238 0.0391 0.039
Echinococcus granulosus transmembrane protease serine 3 0.0189 0.0297 0.0297
Onchocerca volvulus Neurogenic locus notch homolog 0.0037 0.0008 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.1155 0.2134 0.6935
Plasmodium falciparum centrin-1 0.0233 0.0383 0.1241
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0005
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0327 0.0561 0.056
Loa Loa (eye worm) hypothetical protein 0.0046 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.2404 0.4508 0.4508
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0025 0.0024
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0222 0.0612
Loa Loa (eye worm) hypothetical protein 0.0114 0.0155 0.0155
Brugia malayi Animal haem peroxidase family protein 0.043 0.0757 0.0757
Toxoplasma gondii hypothetical protein 0.0246 0.0406 0.1039
Loa Loa (eye worm) hypothetical protein 0.0189 0.0297 0.0297
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0127 0.018 0.0496
Mycobacterium ulcerans hypothetical protein 0.0294 0.0498 0.321
Plasmodium falciparum serine repeat antigen 9 0.0428 0.0751 0.2439
Loa Loa (eye worm) animal heme peroxidase 0.043 0.0757 0.0757
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Loa Loa (eye worm) hypothetical protein 0.0077 0.0086 0.0086
Onchocerca volvulus Prolyl endopeptidase homolog 0.2085 0.3901 0.8653
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0848 0.155 0.4511
Mycobacterium tuberculosis Hypothetical protein 0.0294 0.0498 0.1448
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0189 0.0297 0.0297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Onchocerca volvulus Putative cubilin 0.004 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0496 0.0882 0.0882
Brugia malayi hypothetical protein 0.0045 0.0025 0.0025
Mycobacterium ulcerans proteasome PrcB 0.0157 0.0237 0.1524
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0133 0.0192 0.0621
Plasmodium vivax unspecified product 0.0496 0.0882 0.2864
Leishmania major calcineurin B subunit, putative 0.0233 0.0383 0.0978
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Leishmania major i/6 autoantigen-like protein 0.0233 0.0383 0.0978
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0026 0.0026
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0924 0.1694 0.1694
Echinococcus granulosus neurogenic locus notch protein 0.0037 0.0008 0.0008
Leishmania major programmed cell death 6 protein-like protein 0.0233 0.0383 0.0978
Loa Loa (eye worm) animal heme peroxidase 0.043 0.0757 0.0757
Brugia malayi programmed cell death protein 6 0.0233 0.0383 0.0383
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0109 0.03
Giardia lamblia Histone deacetylase 0.009 0.0109 0.03
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0238 0.0391 0.039
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0005 0.001
Giardia lamblia Proteasome subunit beta type 1 0.007 0.0072 0.0196
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0044 0.0022 0.0022
Schistosoma mansoni cathepsin D (A01 family) 0.0235 0.0386 0.0386
Onchocerca volvulus 0.0233 0.0383 0.0837
Loa Loa (eye worm) hypothetical protein 0.0048 0.0031 0.0031
Trichomonas vaginalis myosin light chain 1, putative 0.0233 0.0383 0.1057
Loa Loa (eye worm) proteasome subunit beta type 1 0.007 0.0072 0.0072
Toxoplasma gondii aspartyl protease ASP1 0.0044 0.0022 0.0055
Trypanosoma brucei protein I/6 0.0233 0.0383 0.0978
Echinococcus granulosus dnaJ subfamily B 0.0864 0.1581 0.158
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.0751 0.075
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0238 0.0391 0.039
Echinococcus granulosus protein jagged 2 0.0035 0.0006 0.0005
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.028 0.047 0.047
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0051 0.005
Brugia malayi prolyl oligopeptidase family protein 0.0246 0.0406 0.0406
Loa Loa (eye worm) hypothetical protein 0.0046 0.0026 0.0026
Echinococcus granulosus histone deacetylase 8 0.0043 0.0021 0.002
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0246 0.0406 0.1318
Trypanosoma brucei calpain-like protein, putative 0.1439 0.2674 0.6853
Plasmodium vivax vivapain-2 0.1652 0.3077 1
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0848 0.155 0.1549
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0233 0.0383 0.0382
Onchocerca volvulus 0.0051 0.0035 0.0065
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0344 0.0593 0.0593
Plasmodium falciparum proteasome subunit beta type-1, putative 0.007 0.0072 0.023
Loa Loa (eye worm) notch protein 0.0037 0.0008 0.0008
Trypanosoma cruzi cysteine protease, putative 0.0924 0.1694 0.1694
Onchocerca volvulus 0.0189 0.0297 0.0648
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Toxoplasma gondii cathepsin CPC2 0.0428 0.0751 0.1924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0155 0.0426
Echinococcus multilocularis inhibitor of apoptosis protein 0.0189 0.0298 0.0297
Brugia malayi EF hand family protein 0.0238 0.0391 0.0391
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0233 0.0383 0.1241
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0008
Echinococcus granulosus histone deacetylase 3 0.009 0.0109 0.0108
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Echinococcus multilocularis neurocalcin 0.0233 0.0383 0.0382
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0739 0.2043
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Brugia malayi Pepsin A precursor 0.0044 0.0022 0.0022
Echinococcus multilocularis peroxidasin 0.043 0.0757 0.0756
Giardia lamblia Alanyl dipeptidyl peptidase 0.0246 0.0406 0.1122
Schistosoma mansoni cathepsin D (A01 family) 0.0235 0.0386 0.0386
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0344 0.0593 0.1519
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Toxoplasma gondii microneme protein MIC4 0.0046 0.0026 0.0064
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0924 0.1694 0.1694
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0157 0.0237 0.0236
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0078 0.0225
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Loa Loa (eye worm) fli-1 protein 0.0213 0.0345 0.0345
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0052 0.0037 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Loa Loa (eye worm) calpain 0.1439 0.2674 0.2674
Trypanosoma brucei Component of motile flagella 41 0.0233 0.0383 0.0978
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0074 0.0469
Schistosoma mansoni neprilysin-2 (M13 family) 0.0052 0.0037 0.0036
Onchocerca volvulus 0.0189 0.0298 0.0649
Echinococcus granulosus Regulator of G protein signaling 20 0.0045 0.0025 0.0024
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0222 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0924 0.1694 0.469
Schistosoma mansoni hypothetical protein 0.0421 0.0739 0.0738
Brugia malayi beta-lactamase 0.0073 0.0078 0.0078
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0074 0.0073
Schistosoma mansoni chromatin regulatory protein sir2 0.0127 0.018 0.0179
Echinococcus granulosus chromatin regulatory protein sir2 0.0127 0.018 0.0179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0428 0.0751 0.2078
Giardia lamblia Hypothetical protein 0.0428 0.0751 0.2078
Schistosoma mansoni notch 0.0035 0.0006 0.0005
Plasmodium vivax aspartyl protease, putative 0.0044 0.0022 0.007
Plasmodium falciparum plasmepsin IX 0.0208 0.0334 0.1084
Entamoeba histolytica cysteine protease, putative 0.0428 0.0751 0.2439
Trypanosoma brucei centrin, putative 0.0233 0.0383 0.0978
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0045 0.0025 0.0079
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0421 0.0738 0.0737
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0428 0.0751 0.2439
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Loa Loa (eye worm) hypothetical protein 0.0107 0.0142 0.0142
Leishmania major cysteine peptidase A (CPA) 0.1652 0.3077 0.7887
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0924 0.1694 0.469
Plasmodium falciparum plasmepsin VIII, putative 0.0044 0.0022 0.007
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.014 0.0206 0.0205
Toxoplasma gondii hypothetical protein 0.0046 0.0026 0.0064
Leishmania major kinesin, putative 0.1018 0.1874 0.4803
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0078 0.0077
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0189 0.0298 0.0297
Echinococcus granulosus gamma secretase subunit aph 1 0.028 0.047 0.0469
Trichomonas vaginalis conserved hypothetical protein 0.0233 0.0383 0.1057
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.6853
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0025 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1763 0.3288 0.8428
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0027 0.0026
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0233 0.0383 0.0382
Brugia malayi Peptidase C13 family protein 0.0149 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0189 0.0297 0.0297
Trichomonas vaginalis centrin, putative 0.0233 0.0383 0.1057
Brugia malayi EGF-like domain containing protein 0.0035 0.0006 0.0006
Mycobacterium ulcerans transglutaminase family protein 0.0294 0.0498 0.321
Entamoeba histolytica histone deacetylase, putative 0.009 0.0109 0.0353
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0026 0.0064
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0078 0.0499
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Echinococcus granulosus Mastin 0.0189 0.0297 0.0297
Schistosoma mansoni histone deacetylase 4 5 0.0101 0.013 0.013
Echinococcus granulosus caspase 2 0.0295 0.05 0.05
Trypanosoma brucei calpain-like protein, putative 0.1439 0.2674 0.6853
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0739 0.0738
Brugia malayi Cathepsin L-like precursor 0.1155 0.2134 0.2134
Loa Loa (eye worm) hypothetical protein 0.0189 0.0297 0.0297
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4077 0.7686 0.7686
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0058 0.0048 0.0048
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0233 0.0383 0.0382
Schistosoma mansoni hypothetical protein 0.0189 0.0297 0.0297
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0056 0.0056
Brugia malayi Ets-domain containing protein 0.007 0.0073 0.0073
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.0109 0.03
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0428 0.0751 0.2439
Loa Loa (eye worm) hypothetical protein 0.0043 0.0021 0.0021
Onchocerca volvulus Chorion peroxidase homolog 0.043 0.0757 0.1668
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Plasmodium vivax hypothetical protein, conserved 0.0114 0.0155 0.05
Trypanosoma brucei C-8 sterol isomerase, putative 0.0365 0.0632 0.1618
Brugia malayi beta-lactamase family protein 0.0073 0.0078 0.0078
Toxoplasma gondii histone deacetylase HDAC3 0.009 0.0109 0.0278
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0189 0.0297 0.0297
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Loa Loa (eye worm) hypothetical protein 0.0035 0.0005 0.0005
Leishmania major hypothetical protein, conserved 0.0421 0.0739 0.1891
Echinococcus multilocularis calumenin 0.0238 0.0391 0.039
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Giardia lamblia Cathepsin B precursor 0.1933 0.3612 1
Toxoplasma gondii subtilisin SUB12 0.0046 0.0026 0.0064
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0026 0.0026
Schistosoma mansoni cell polarity protein 0.0035 0.0006 0.0005
Echinococcus granulosus calcium uptake protein 1 0.0238 0.0391 0.039
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.007 0.0072 0.0182
Loa Loa (eye worm) hypothetical protein 0.006 0.0053 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5295 1 1
Brugia malayi hypothetical protein 0.0045 0.0025 0.0025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0215 0.0215
Plasmodium vivax unspecified product 0.0924 0.1694 0.5504
Loa Loa (eye worm) hypothetical protein 0.1652 0.3077 0.3077
Trichomonas vaginalis calpain, putative 0.0421 0.0739 0.2043
Trichomonas vaginalis peptide N-glycanase, putative 0.0294 0.0498 0.1377
Schistosoma mansoni neuronal calcium sensor 0.0233 0.0383 0.0382
Schistosoma mansoni calmodulin 0.0233 0.0383 0.0382
Trypanosoma brucei hypothetical protein 0.0421 0.0739 0.1891
Trichomonas vaginalis hypothetical protein 0.0421 0.0739 0.2043
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1933 0.3612 0.3611
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0428 0.0751 0.2078
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.001 0.001
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0025 0.0024
Onchocerca volvulus 0.018 0.0282 0.0613
Brugia malayi Animal haem peroxidase family protein 0.043 0.0757 0.0757
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0045 0.0025 0.0024
Echinococcus granulosus cathepsin L cysteine protease 0.0924 0.1694 0.1694
Echinococcus multilocularis glycogen phosphorylase 0.0121 0.0169 0.0169
Echinococcus multilocularis calpain 0.1439 0.2674 0.2673
Onchocerca volvulus 0.0037 0.0008 0.0006
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1933 0.3612 0.3611
Loa Loa (eye worm) hypothetical protein 0.009 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0189 0.0297 0.0297
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0344 0.0593 0.0593
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1933 0.3612 0.9257
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0102 0.0133 0.0133
Entamoeba histolytica cysteine protease, putative 0.0428 0.0751 0.2439
Entamoeba histolytica calcium-binding protein, putative 0.0233 0.0383 0.1241
Onchocerca volvulus Peroxidasin homolog 0.043 0.0757 0.1668
Loa Loa (eye worm) hypothetical protein 0.1155 0.2134 0.2134
Echinococcus granulosus caspase 3 0.0214 0.0345 0.0344
Trypanosoma brucei histone deacetylase 2 0.0043 0.0021 0.0052
Plasmodium vivax aspartyl proteinase, putative 0.0044 0.0022 0.007
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0078 0.0225
Onchocerca volvulus 0.1652 0.3077 0.6823
Giardia lamblia Cysteine protease 0.0428 0.0751 0.2078
Onchocerca volvulus 0.0071 0.0073 0.015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0428 0.0751 0.2078
Onchocerca volvulus Legumain homolog 0.0149 0.0222 0.048
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0238 0.0391 0.1266
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0215 0.0215
Plasmodium falciparum cysteine proteinase falcipain 1 0.0924 0.1694 0.5504
Loa Loa (eye worm) fibroinase 0.1652 0.3077 0.3077
Echinococcus multilocularis chromatin regulatory protein sir2 0.0127 0.018 0.0179
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0428 0.0751 0.0751
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Onchocerca volvulus 0.043 0.0757 0.1668
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0327 0.0561 0.056
Schistosoma mansoni laminin gamma-3 chain 0.0035 0.0006 0.0005
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.013 0.013
Brugia malayi cathepsin F-like cysteine proteinase 0.0496 0.0882 0.0882
Onchocerca volvulus Cathepsin L homolog 0.0428 0.0751 0.1656
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0739 0.0738
Echinococcus multilocularis prolyl endopeptidase 0.2085 0.3901 0.3901
Trypanosoma cruzi cysteine peptidase, putative 0.1763 0.3288 0.3288
Echinococcus multilocularis caspase 0.0327 0.0561 0.056
Onchocerca volvulus 0.0044 0.0022 0.0037
Brugia malayi Peptidase family M13 containing protein 0.0102 0.0133 0.0133
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0114 0.0155 0.0394
Entamoeba histolytica calmodulin, putative 0.0233 0.0383 0.1241
Trypanosoma brucei I/6 autoantigen 0.0233 0.0383 0.0978
Schistosoma mansoni cathepsin F (C01 family) 0.1652 0.3077 0.3077
Giardia lamblia Cathepsin L precursor 0.0428 0.0751 0.2078
Leishmania major centrin, putative 0.0233 0.0383 0.0978
Plasmodium falciparum serine repeat antigen 7 0.0428 0.0751 0.2439
Giardia lamblia Cysteine protease 0.0428 0.0751 0.2078
Echinococcus multilocularis cathepsin L 0.0428 0.0751 0.075
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0739 0.0738
Loa Loa (eye worm) hypothetical protein 0.0075 0.0082 0.0082
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0052 0.0039 0.011
Brugia malayi regulator of G-protein signaling egl-10 0.0045 0.0025 0.0025
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0428 0.0751 0.2439
Plasmodium falciparum serine repeat antigen 1 0.0428 0.0751 0.2439
Loa Loa (eye worm) hypothetical protein 0.0077 0.0086 0.0086
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1439 0.2674 0.2673
Echinococcus multilocularis neurogenic locus notch protein 0.0035 0.0006 0.0005
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0026 0.0064
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0037 0.001 0.0059
Loa Loa (eye worm) hypothetical protein 0.2825 0.5307 0.5307
Entamoeba histolytica protein kinase, putative 0.1018 0.1874 0.609
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0025 0.0024
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.007 0.0072 0.0071
Brugia malayi Cytochrome P450 family protein 0.0037 0.001 0.001
Echinococcus multilocularis Tolloid protein 1 0.0045 0.0024 0.0023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0215 0.0215
Entamoeba histolytica hypothetical protein, conserved 0.0238 0.0391 0.1266
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0026 0.0026
Echinococcus granulosus notch 0.0035 0.0006 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0215 0.0215
Echinococcus granulosus histone deacetylase 0.0101 0.013 0.013
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0189 0.0297 0.0297
Echinococcus multilocularis neurogenic locus protein delta 0.0035 0.0006 0.0005
Leishmania major centrin, putative 0.0233 0.0383 0.0978
Schistosoma mansoni cathepsin F (C01 family) 0.1155 0.2134 0.2134
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0025
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0924 0.1694 0.1694
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.4077 0.7686 0.7686
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Echinococcus granulosus calumenin 0.0238 0.0391 0.039
Toxoplasma gondii histone lysine methyltransferase SET1 0.017 0.0262 0.067
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0005 0.0012
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0157 0.0237 0.0687
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0365 0.0632 0.0632
Toxoplasma gondii proteasome subunit beta type 1, putative 0.007 0.0072 0.0182
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0051 0.0326
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Echinococcus multilocularis Glycosyl transferase, family 35 0.0121 0.0169 0.0169
Schistosoma mansoni gamma-secretase subunit aph-1 0.028 0.047 0.0469
Brugia malayi Histone deacetylase family protein 0.0101 0.013 0.013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0739 0.0738
Echinococcus multilocularis fibropellin Ia 0.0035 0.0006 0.0005
Brugia malayi calpain 7 0.1439 0.2674 0.2674
Brugia malayi CXXC zinc finger family protein 0.0088 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Leishmania major histone deacetylase, putative 0.009 0.0109 0.0278
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0109 0.03
Echinococcus multilocularis apoptotic protease activating factor 1 0.0182 0.0285 0.0284
Trypanosoma cruzi metacaspase 5, putative 0.0114 0.0155 0.0154
Trichomonas vaginalis calmodulin, putative 0.0233 0.0383 0.1057
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3843 0.7243 0.7242
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0078 0.0077
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0073 0.0078 0.0078
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0222 0.0612
Schistosoma mansoni cellular tumor antigen P53 0.0107 0.0142 0.0141
Loa Loa (eye worm) hypothetical protein 0.0428 0.0751 0.0751
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0046 0.0026 0.0026
Schistosoma mansoni calpain-7 (C02 family) 0.1442 0.268 0.2679
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0051 0.014
Echinococcus multilocularis protein jagged 1 0.0035 0.0006 0.0005
Onchocerca volvulus 0.0294 0.0498 0.1094
Echinococcus multilocularis histone deacetylase 3 0.009 0.0109 0.0108
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0189 0.0297 0.0297
Brugia malayi Trypsin family protein 0.0189 0.0297 0.0297
Echinococcus multilocularis histone deacetylase 6 0.0101 0.013 0.013
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0189 0.0297 0.0297
Onchocerca volvulus 0.0046 0.0026 0.0045
Onchocerca volvulus Peroxidase homolog 0.043 0.0757 0.1668
Schistosoma mansoni notch 0.0037 0.0008 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Loa Loa (eye worm) TK/ROR protein kinase 0.0071 0.0073 0.0073
Onchocerca volvulus 0.0073 0.0078 0.0161
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0005 0.0012
Entamoeba histolytica cysteine proteinase 1, putative 0.0924 0.1694 0.5504
Schistosoma mansoni peroxidasin 0.043 0.0757 0.0756
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0045 0.0025 0.0024
Loa Loa (eye worm) animal heme peroxidase 0.043 0.0757 0.0757
Trypanosoma brucei proteasome beta 6 subunit 0.007 0.0072 0.0182
Leishmania major hypothetical protein, conserved 0.0073 0.0078 0.0198
Schistosoma mansoni peroxidasin 0.043 0.0757 0.0756
Brugia malayi regulator of G-protein signaling rgs-7 0.0045 0.0025 0.0025
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0222 0.0612
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0051 0.0051
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.6853
Brugia malayi EGF-like domain containing protein 0.0035 0.0006 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0233 0.0383 0.0978
Onchocerca volvulus Histone deacetylase 10 homolog 0.0043 0.0021 0.0034
Brugia malayi Cathepsin L-like precursor 0.1652 0.3077 0.3077
Plasmodium falciparum serine repeat antigen 2 0.0428 0.0751 0.2439
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0035 0.0006 0.0005
Loa Loa (eye worm) calpain family protein 1 0.2825 0.5307 0.5307
Toxoplasma gondii cathepsin B 0.1933 0.3612 0.9257
Onchocerca volvulus Glycogen phosphorylase homolog 0.0121 0.0169 0.0364
Echinococcus multilocularis slit 2 protein 0.0035 0.0006 0.0005
Echinococcus granulosus EF hand domain containing family member A2 0.0238 0.0391 0.039
Brugia malayi aspartic protease BmAsp-2, identical 0.0044 0.0022 0.0022
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.009 0.0109 0.03
Trypanosoma cruzi hypothetical protein, conserved 0.0246 0.0406 0.0405
Brugia malayi Angiotensin-converting enzyme family protein 0.1212 0.2243 0.2243
Echinococcus granulosus slit 2 protein 0.0035 0.0006 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0069 0.0068
Echinococcus granulosus protein jagged 2 0.0035 0.0006 0.0005
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0599 0.1077 0.1076
Loa Loa (eye worm) hypothetical protein 0.0043 0.0021 0.0021
Leishmania major calmodulin, putative 0.0233 0.0383 0.0978
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.014 0.0206 0.0205
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0045 0.0025 0.0062
Entamoeba histolytica cysteine proteinase, putative 0.0924 0.1694 0.5504
Plasmodium falciparum plasmepsin VI 0.0044 0.0022 0.007
Leishmania major proteasome beta 5 subunit, putative 0.0157 0.0237 0.0605
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0189 0.0297 0.0297
Giardia lamblia Hypothetical protein 0.0127 0.018 0.0496
Loa Loa (eye worm) hypothetical protein 0.0077 0.0086 0.0086
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0045 0.0025 0.0079
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0051 0.0129
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0078 0.0214
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Schistosoma mansoni reticulocalbin 0.0233 0.0383 0.0382
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Plasmodium vivax centrin-1, putative 0.0233 0.0383 0.1241
Onchocerca volvulus 0.0046 0.0026 0.0045
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0005 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) beta-lactamase 0.0073 0.0078 0.0078
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.3843 0.7243 0.7243
Echinococcus multilocularis programmed cell death protein 0.0241 0.0397 0.0396
Brugia malayi Cytochrome P450 family protein 0.0062 0.0056 0.0056
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0428 0.0751 0.0751
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0599 0.1077 0.238
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0739 0.2043
Giardia lamblia Cathepsin B precursor 0.0428 0.0751 0.2078
Giardia lamblia Cathepsin B precursor 0.0428 0.0751 0.2078
Plasmodium vivax histone deacetylase, putative 0.0043 0.0021 0.0066
Brugia malayi Cell death protein 3 precursor 0.0295 0.05 0.05
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0045 0.0025 0.0024
Brugia malayi PAN domain containing protein 0.0046 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0739 0.2043
Echinococcus granulosus cathepsin b 0.5295 1 1
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0005
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0599 0.1077 0.1076
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0127 0.018 0.0459
Mycobacterium tuberculosis Conserved protein 0.0073 0.0078 0.0225
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0074 0.0469
Toxoplasma gondii histone deacetylase HDAC4 0.0043 0.0021 0.0052
Plasmodium falciparum serine repeat antigen 3 0.0428 0.0751 0.2439
Brugia malayi cathepsin Z-like cysteine proteinase 0.0428 0.0751 0.0751
Trypanosoma cruzi oligopeptidase b 0.0848 0.155 0.1549
Loa Loa (eye worm) calpain 5 0.1018 0.1874 0.1874
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0848 0.155 1
Schistosoma mansoni cathepsin S (C01 family) 0.0428 0.0751 0.075
Schistosoma mansoni memapsin-2 (A01 family) 0.0538 0.0962 0.0961
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0344 0.0593 0.0593
Echinococcus multilocularis EF hand domain containing family member A2 0.0233 0.0383 0.0382
Trypanosoma cruzi metacaspase, putative 0.0114 0.0155 0.0154
Echinococcus multilocularis histone deacetylase 0.0101 0.013 0.013
Plasmodium vivax vivapain-1 0.0924 0.1694 0.5504
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0044 0.0022 0.0055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Brugia malayi Histone deacetylase 1 0.009 0.0109 0.0109
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0157 0.0237 0.0654
Toxoplasma gondii EGF family domain-containing protein 0.0035 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0246 0.0406 0.0406
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0428 0.0751 0.2439
Echinococcus granulosus histone deacetylase 6 0.0101 0.013 0.013
Brugia malayi Calmodulin-like protein 0.0233 0.0383 0.0383
Trypanosoma brucei Calpain-like protein 1.1 0.0421 0.0739 0.1891
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0045 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0428 0.0751 0.2078
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0848 0.155 1
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0072 0.0071
Entamoeba histolytica cysteine proteinase, putative 0.0924 0.1694 0.5504
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0222 0.0612
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Onchocerca volvulus 0.0046 0.0026 0.0045
Trypanosoma cruzi cysteine peptidase, putative 0.1652 0.3077 0.3077
Loa Loa (eye worm) hypothetical protein 0.0421 0.0739 0.0739
Trichomonas vaginalis calmodulin, putative 0.0233 0.0383 0.1057
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0107 0.0107
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.5295 1 1
Onchocerca volvulus Cathepsin L homolog 0.1652 0.3077 0.6823
Echinococcus multilocularis hypothetical protein 0.1439 0.2674 0.2673
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0233 0.0383 0.0382
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0072 0.0071
Brugia malayi NAD-dependent deacetylase SIRT1 0.014 0.0206 0.0206
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0078 0.0214
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0189 0.0298 0.0297
Schistosoma mansoni caspase-3 (C14 family) 0.0327 0.0561 0.056
Leishmania major cathepsin L-like protease 0.1652 0.3077 0.7887
Brugia malayi cathepsin Z-like cysteine proteinase 0.0428 0.0751 0.0751
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0428 0.0751 0.2439
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0222 0.0612
Plasmodium falciparum peptidase, putative 0.0246 0.0406 0.1318
Echinococcus granulosus histone deacetylase 6 0.0107 0.0142 0.0141
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0305 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0428 0.0751 0.2078
Giardia lamblia Glycogen phosphorylase 0.0121 0.0169 0.0467
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0222 0.0612
Giardia lamblia Cysteine protease 0.0428 0.0751 0.2078
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0222 0.0612
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0025 0.0067
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0051 0.014
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0428 0.0751 0.075
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0155 0.0426
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0428 0.0751 0.2078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0496 0.0882 0.0882
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Echinococcus granulosus neurocalcin 0.0233 0.0383 0.0382
Schistosoma mansoni histone deacetylase 1 2 3 0.0043 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0073 0.0078 0.0078
Entamoeba histolytica cysteine protease, putative 0.0428 0.0751 0.2439
Echinococcus granulosus tissue type plasminogen activator 0.0071 0.0073 0.0072
Trypanosoma cruzi caltractin, putative 0.0233 0.0383 0.0382
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0599 0.1077 0.1076
Loa Loa (eye worm) calmodulin-like protein 0.0233 0.0383 0.0383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0428 0.0751 0.2078
Echinococcus multilocularis cathepsin L cysteine protease 0.1652 0.3077 0.3077
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Echinococcus multilocularis endothelin converting enzyme 1 0.0102 0.0133 0.0132
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Trichomonas vaginalis calcium binding protein, putative 0.0233 0.0383 0.1057
Trypanosoma cruzi histone deacetylase 1, putative 0.009 0.0109 0.0108
Onchocerca volvulus 0.0428 0.0751 0.1656
Loa Loa (eye worm) hypothetical protein 0.0046 0.0027 0.0027
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0026 0.0026
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0189 0.0298 0.0298
Onchocerca volvulus 0.0189 0.0297 0.0648
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0022 0.0022
Brugia malayi proteasome subunit beta type 1 0.007 0.0072 0.0072
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0027 0.0026
Loa Loa (eye worm) transcriptional regulator 0.0033 0.0001 0.0001
Mycobacterium ulcerans putative transglutaminase-like protein 0.0294 0.0498 0.321
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0045 0.0025 0.0024
Brugia malayi calpain D 0.0421 0.0739 0.0739
Leishmania major calpain protease-like protein 0.0421 0.0739 0.1891
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0031 0.0031
Brugia malayi Papain family cysteine protease containing protein 0.0924 0.1694 0.1694
Echinococcus multilocularis caspase 2 0.0295 0.05 0.05
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.0751 0.075
Echinococcus multilocularis glycogen phosphorylase 0.0121 0.0169 0.0169
Leishmania major cathepsin L-like protease 0.1652 0.3077 0.7887
Brugia malayi prolyl oligopeptidase family protein 0.0599 0.1077 0.1077
Entamoeba histolytica cysteine proteinase 2 0.0924 0.1694 0.5504
Leishmania major hypothetical protein, conserved 0.0071 0.0073 0.0185
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0005
Trypanosoma brucei histone deacetylase 4 0.0101 0.013 0.0332
Trypanosoma brucei kinesin, putative 0.1018 0.1874 0.4803
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0039 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0078 0.0214
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0068 0.0069 0.0068
Loa Loa (eye worm) hypothetical protein 0.5295 1 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0189 0.0297 0.0297
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0025 0.0024
Toxoplasma gondii EFHC1, putative 0.0233 0.0383 0.0978
Toxoplasma gondii kringle domain-containing protein 0.0071 0.0073 0.0185
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0896 0.1641 0.1641
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0044 0.0022 0.0022
Trypanosoma brucei oligopeptidase b 0.0848 0.155 0.397
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0025 0.0025
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0051 0.0147
Trypanosoma brucei histone deacetylase 3 0.0101 0.013 0.0332
Trichomonas vaginalis calcineurin B subunit, putative 0.0238 0.0391 0.1079
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Trichomonas vaginalis esterase, putative 0.0073 0.0078 0.0214
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2085 0.3901 0.3901
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0215 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0025 0.0024
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0025 0.0025
Schistosoma mansoni calpain-2 (C02 family) 0.0421 0.0739 0.0738
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0188 0.0188
Loa Loa (eye worm) histone deacetylase 1 0.009 0.0109 0.0109
Toxoplasma gondii histone deacetylase HDAC1 0.0101 0.013 0.0332
Echinococcus multilocularis caspase 8 0.0114 0.0155 0.0154
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0025 0.0024
Entamoeba histolytica hypothetical protein 0.0428 0.0751 0.2439
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1439 0.2674 0.2673
Trypanosoma brucei histone deacetylase 1 0.009 0.0109 0.0278
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0025 0.0066
Brugia malayi Cadherin domain containing protein 0.0035 0.0006 0.0006
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0428 0.0751 0.2078
Trypanosoma cruzi cysteine peptidase, putative 0.1763 0.3288 0.3288
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0071 0.0074 0.0073
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0044 0.0022 0.0021
Plasmodium falciparum plasmepsin V 0.0044 0.0022 0.007
Leishmania major C-8 sterol isomerase-like protein 0.0365 0.0632 0.1618
Trypanosoma brucei Calpain-like protein 2 0.0421 0.0739 0.1891
Brugia malayi GCC2 and GCC3 family protein 0.0037 0.0008 0.0008
Loa Loa (eye worm) transcriptional regulator 0.0127 0.018 0.018
Echinococcus granulosus apoptotic protease activating factor 1 0.0182 0.0285 0.0284
Trypanosoma brucei calmodulin, putative 0.0233 0.0383 0.0978
Schistosoma mansoni reticulocalbin 0.0238 0.0391 0.039
Trichomonas vaginalis glycogen phosphorylase, putative 0.0121 0.0169 0.0467
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0025 0.0024
Brugia malayi histone deacetylase 3 (HD3) 0.009 0.0109 0.0109
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.0037 0.0036
Echinococcus multilocularis notch 0.0035 0.0006 0.0005
Toxoplasma gondii ABC1 family protein 0.0073 0.0078 0.0198
Entamoeba histolytica prolyl oligopeptidase family protein 0.0246 0.0406 0.1318
Toxoplasma gondii peptidase family M13 protein 0.0102 0.0133 0.0339
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0428 0.0751 0.2439
Plasmodium vivax serine-repeat antigen (SERA) 0.0428 0.0751 0.2439
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Brugia malayi calpain family protein 1 0.3843 0.7243 0.7243
Loa Loa (eye worm) hypothetical protein 0.0189 0.0298 0.0298
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0069 0.0068
Echinococcus multilocularis dnaJ subfamily B 0.0864 0.1581 0.158
Echinococcus multilocularis microtubule associated protein 2 0.161 0.2998 0.2997
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0428 0.0751 0.0751
Brugia malayi hypothetical protein 0.018 0.0282 0.0282
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0052 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0073 0.0078 0.0078
Trypanosoma cruzi cruzipain precursor, putative 0.0496 0.0882 0.0881
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0044 0.0022 0.0055
Loa Loa (eye worm) hypothetical protein 0.0428 0.0751 0.0751
Onchocerca volvulus 0.0073 0.0078 0.0161
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0051 0.5
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0005
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0233 0.0383 0.0382
Toxoplasma gondii proteasome subunit beta type, putative 0.0157 0.0237 0.0605
Toxoplasma gondii cathepsin CPL 0.1652 0.3077 0.7887
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Echinococcus granulosus tumor protein p63 0.0731 0.1327 0.1326
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0127 0.018 0.0582
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0025 0.0024
Echinococcus multilocularis fat cadherin tumor suppressor 0.0035 0.0006 0.0005
Trypanosoma brucei Aph-1 protein, putative 0.0109 0.0146 0.0372
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0000000000040726 0.0000000000040726
Echinococcus granulosus neural cadherin 0.0035 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0428 0.0751 0.2439
Brugia malayi Pre-SET motif family protein 0.0464 0.0821 0.0821
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0739 0.0738
Loa Loa (eye worm) hypothetical protein 0.0073 0.0078 0.0078
Onchocerca volvulus Peroxidasin homolog 0.043 0.0757 0.1668
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.6853
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0008
Schistosoma mansoni cpg binding protein 0.0088 0.0107 0.0106
Echinococcus multilocularis cysteine protease 0.1652 0.3077 0.3077
Brugia malayi hypothetical protein 0.0044 0.0022 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0078 0.0198
Leishmania major histone deacetylase, putative 0.009 0.0109 0.0278
Brugia malayi prolyl oligopeptidase family protein 0.2085 0.3901 0.3901
Entamoeba histolytica hypothetical protein 0.0045 0.0025 0.0078
Loa Loa (eye worm) hypothetical protein 0.0233 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0025
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0025 0.0025
Schistosoma mansoni histone deacetylase 0.009 0.0109 0.0108
Echinococcus granulosus EF hand domain containing family member A2 0.0233 0.0383 0.0382
Leishmania major histone deacetylase, putative 0.0101 0.013 0.0332
Schistosoma mansoni centrin-related 0.0233 0.0383 0.0382
Trichomonas vaginalis glycogen phosphorylase, putative 0.0121 0.0169 0.0467
Onchocerca volvulus 0.2404 0.4508 1
Schistosoma mansoni rab 0.0233 0.0383 0.0382
Echinococcus multilocularis protein jagged 2 0.0035 0.0006 0.0005
Brugia malayi EGF-like domain containing protein 0.0035 0.0006 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0031 0.0031
Schistosoma mansoni ets-related 0.0213 0.0345 0.0344
Toxoplasma gondii microneme protein, putative 0.0046 0.0026 0.0064
Trypanosoma brucei mitochondrial calcium uptake 1 0.0233 0.0383 0.0978
Schistosoma mansoni hypothetical protein 0.0864 0.1581 0.158
Mycobacterium ulcerans lipase LipD 0.0073 0.0078 0.0499
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0025 0.0024
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.0738
Mycobacterium tuberculosis Long conserved protein 0.0294 0.0498 0.1448
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4077 0.7686 0.7686
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0005 0.001
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Loa Loa (eye worm) hypothetical protein 0.0077 0.0086 0.0086
Echinococcus multilocularis histone deacetylase 7 0.0101 0.013 0.013
Onchocerca volvulus 0.0046 0.0027 0.0047
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0025 0.0024
Loa Loa (eye worm) EF hand family protein 0.0233 0.0383 0.0383
Onchocerca volvulus 0.1155 0.2134 0.4728
Plasmodium vivax histone deacetylase 1, putative 0.009 0.0109 0.0353
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Plasmodium vivax plasmepsin V, putative 0.0044 0.0022 0.007
Leishmania major cathepsin L-like protease 0.1652 0.3077 0.7887
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Brugia malayi hypothetical protein 0.0044 0.0022 0.0022
Brugia malayi calpain 5 0.1018 0.1874 0.1874
Trypanosoma brucei Calpain-like protein 1.2 0.0421 0.0739 0.1891
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0025 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0246 0.0406 0.0405
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1212 0.2243 0.2243
Echinococcus granulosus programmed cell death protein 0.0241 0.0397 0.0396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Leishmania major cytochrome p450-like protein 0.0037 0.001 0.0023
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0052 0.0039 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1652 0.3077 0.852
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0037 0.0008 0.0008
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0848 0.155 0.397
Brugia malayi beta-lactamase family protein 0.0073 0.0078 0.0078
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0428 0.0751 0.0751
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0155 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0155 0.0426
Plasmodium falciparum serine repeat antigen 5 0.0428 0.0751 0.2439
Entamoeba histolytica cysteine proteinase, putative 0.0924 0.1694 0.5504
Leishmania major cathepsin L-like protease 0.1763 0.3288 0.8428
Brugia malayi calcium-binding protein 0.0233 0.0383 0.0383
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0127 0.018 0.0179
Mycobacterium leprae Conserved hypothetical protein 0.0294 0.0498 0.2853
Plasmodium falciparum histone deacetylase 2 0.0101 0.013 0.0421
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0074 0.0073
Brugia malayi A-kinase anchor protein 10, precursor 0.0045 0.0025 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0074 0.0469
Plasmodium vivax vivapain-3 0.0924 0.1694 0.5504
Brugia malayi fibroinase precursor 0.0428 0.0751 0.0751
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Schistosoma mansoni glycogen phosphorylase 0.0052 0.0039 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Echinococcus granulosus glycogen phosphorylase 0.0121 0.0169 0.0169
Plasmodium falciparum cysteine proteinase falcipain 3 0.1652 0.3077 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) hypothetical protein 0.043 0.0757 0.0757
Onchocerca volvulus 0.0046 0.0026 0.0045
Brugia malayi hypothetical protein 0.0189 0.0297 0.0297
Giardia lamblia Cathepsin B precursor 0.1933 0.3612 1
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0027 0.0026
Brugia malayi gamma-secretase subunit aph-1 0.028 0.047 0.047
Schistosoma mansoni cercarial elastase (S01 family) 0.0189 0.0297 0.0297
Echinococcus multilocularis expressed protein 0.0881 0.1613 0.1612
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1652 0.3077 0.852
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0027 0.0026
Onchocerca volvulus 0.0189 0.0297 0.0648
Trypanosoma brucei centrin, putative 0.0233 0.0383 0.0978
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0025 0.0066
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0233 0.0383 0.1241
Schistosoma mansoni septate junction protein 0.0035 0.0006 0.0005
Trichomonas vaginalis calmodulin, putative 0.0233 0.0383 0.1057
Loa Loa (eye worm) Notch2 0.0037 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1652 0.3077 0.852
Loa Loa (eye worm) hypothetical protein 0.0496 0.0882 0.0882
Schistosoma mansoni mixed-lineage leukemia protein mll 0.019 0.03 0.0299
Brugia malayi hypothetical protein 0.0099 0.0126 0.0126
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0109 0.03
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1439 0.2674 0.6853
Loa Loa (eye worm) hypothetical protein 0.0428 0.0751 0.0751
Brugia malayi Cadherin domain containing protein 0.0035 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0924 0.1694 0.5504
Plasmodium vivax aspartyl protease, putative 0.0208 0.0334 0.1084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0924 0.1694 0.4341
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0421 0.0739 0.1891
Entamoeba histolytica cysteine protease, putative 0.0428 0.0751 0.2439
Loa Loa (eye worm) RGS-3 protein 0.0045 0.0025 0.0025
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Trypanosoma cruzi conserved protein 0.0421 0.0739 0.0738
Schistosoma mansoni cathepsin B (C01 family) 0.0428 0.0751 0.075
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0233 0.0383 0.1057
Echinococcus granulosus cathepsin L 0.0924 0.1694 0.1694
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0114 0.0155 0.0426
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0428 0.0751 0.2439
Entamoeba histolytica cysteine proteinase, putative 0.1652 0.3077 1
Echinococcus granulosus histone deacetylase 1 0.009 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0068 0.0069 0.0069
Giardia lamblia Hypothetical protein 0.0294 0.0498 0.1377
Brugia malayi Animal haem peroxidase family protein 0.043 0.0757 0.0757
Leishmania major cathepsin L-like protease 0.1652 0.3077 0.7887
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0045 0.0025 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0025 0.0024
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0421 0.0738 0.0737
Brugia malayi Protein kinase domain containing protein 0.0071 0.0073 0.0073
Onchocerca volvulus 0.0046 0.0026 0.0045
Trypanosoma cruzi histone deacetylase, putative 0.0101 0.013 0.013
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0114 0.0155 0.0394
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0051 0.5
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0021 0.0052
Onchocerca volvulus 0.0107 0.0142 0.0303
Loa Loa (eye worm) hypothetical protein 0.0071 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0428 0.0751 0.2078
Loa Loa (eye worm) hypothetical protein 0.0035 0.0006 0.0006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0189 0.0297 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1652 0.3077 0.852
Giardia lamblia Cathepsin L-like protease 0.0428 0.0751 0.2078
Trichomonas vaginalis histone deacetylase, putative 0.009 0.0109 0.03
Trypanosoma brucei calmodulin, putative 0.0238 0.0391 0.0999
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0739 0.1891
Plasmodium falciparum plasmepsin II 0.0044 0.0022 0.007
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0246 0.0406 0.1318
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0149 0.0222 0.0221
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0037 0.0008 0.0006
Echinococcus granulosus peroxidasin 0.043 0.0757 0.0756
Schistosoma mansoni calpain (C02 family) 0.1439 0.2674 0.2673
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0215 0.0215
Plasmodium vivax aspartyl proteinase, putative 0.0044 0.0022 0.007
Mycobacterium ulcerans beta-lactamase 0.0073 0.0078 0.0499
Echinococcus multilocularis neurogenic locus notch protein 4 0.0035 0.0006 0.0005

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 13.7 mg kg-1 Evaluation of in vitro bronchodilator activity in isolated guinea pig tracheal spiral preparation ChEMBL. 6161252
ED50 (functional) > 30 mg kg-1 In vivo bronchodilator activity in methacholine (intravenous) induced bronchospasm in male Harlan-Sprague-Dawley rats when administered intraduodenally ChEMBL. 6161252

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.