Detailed information for compound 22274

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 432.553 | Formula: C24H36N2O5
  • H donors: 4 H acceptors: 5 LogP: 4.31 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C[C@@H](C(=O)N[C@H]([C@H](C(=O)O)O)CC1CCCCC1)NC(=O)Cc1ccccc1)C
  • InChi: 1S/C24H36N2O5/c1-16(2)13-20(25-21(27)15-18-11-7-4-8-12-18)23(29)26-19(22(28)24(30)31)14-17-9-5-3-6-10-17/h4,7-8,11-12,16-17,19-20,22,28H,3,5-6,9-10,13-15H2,1-2H3,(H,25,27)(H,26,29)(H,30,31)/t19-,20-,22+/m0/s1
  • InChiKey: REHCAGGNZNJENJ-JAXLGGSGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens APH1B gamma secretase subunit Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi gamma-secretase subunit aph-1 Get druggable targets OG5_130831 All targets in OG5_130831
Loa Loa (eye worm) gamma-secretase subunit aph-1 Get druggable targets OG5_130831 All targets in OG5_130831
Schistosoma mansoni gamma-secretase subunit aph-1 Get druggable targets OG5_130831 All targets in OG5_130831
Echinococcus multilocularis gamma secretase subunit aph 1 Get druggable targets OG5_130831 All targets in OG5_130831
Echinococcus granulosus gamma secretase subunit aph 1 Get druggable targets OG5_130831 All targets in OG5_130831
Schistosoma japonicum ko:K06172 anterior pharynx defective 1, putative Get druggable targets OG5_130831 All targets in OG5_130831
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0202 0.1213 0.1213
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0138 0.0781 0.0781
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Trypanosoma brucei Component of motile flagella 41 0.0054 0.0228 0.0201
Leishmania major calmodulin, putative 0.0054 0.0228 0.0201
Echinococcus multilocularis tumor protein p63 0.0354 0.2223 0.2223
Brugia malayi hypothetical protein 0.004 0.0132 0.0132
Plasmodium falciparum proteasome subunit beta type-5 0.0085 0.0433 0.0977
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0066 0.0307 0.0307
Trypanosoma brucei calpain-like protein, putative 0.0395 0.2493 0.2472
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0352 0.2207 0.2186
Schistosoma mansoni cathepsin F (C01 family) 0.0447 0.2835 0.2835
Loa Loa (eye worm) hypothetical protein 0.0139 0.079 0.079
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2472
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.0018 0.0018
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0173 0.0173
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Schistosoma mansoni memapsin-2 (A01 family) 0.0452 0.2869 0.2869
Leishmania major hypothetical protein, conserved 0.0055 0.0231 0.0205
Trypanosoma brucei Aph-1 protein, putative 0.0115 0.0633 0.0608
Plasmodium falciparum serine repeat antigen 7 0.015 0.0863 0.2012
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0284 0.1753 0.1753
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.0018 0.0018
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0059 0.0059
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Plasmodium falciparum cysteine repeat modular protein 1 0.0045 0.0164 0.0329
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Trichomonas vaginalis conserved hypothetical protein 0.0119 0.0657 0.1401
Trichomonas vaginalis calcineurin B subunit, putative 0.0054 0.0228 0.0486
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0009 0.0009
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0027 0.0027
Trypanosoma cruzi calmodulin, putative 0.0054 0.0228 0.0228
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0059 0.0059
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Brugia malayi prolyl oligopeptidase family protein 0.051 0.3258 0.3258
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Loa Loa (eye worm) hypothetical protein 0.0119 0.0657 0.0657
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0059 0.0059
Echinococcus multilocularis cysteine protease 0.0649 0.418 0.418
Schistosoma mansoni calpain (C02 family) 0.0395 0.2493 0.2493
Trypanosoma cruzi caltractin, putative 0.0054 0.0228 0.0228
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0059 0.0059
Echinococcus granulosus survival motor neuron protein 1 0.0245 0.1497 0.1497
Loa Loa (eye worm) hypothetical protein 0.0447 0.2835 0.2835
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.015 0.0863 0.1839
Schistosoma mansoni regulator of G protein signaling 0.004 0.0132 0.0132
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0041 0.014 0.0335
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0059 0.0059
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Onchocerca volvulus 0.0055 0.0231 0.0231
Echinococcus multilocularis calpain A 0.1102 0.7191 0.7191
Echinococcus multilocularis prolyl endopeptidase 0.1525 1 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.015 0.0863 0.2012
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0132 0.0132
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0623 0.4009 1
Treponema pallidum ATP-dependent RNA helicase 0.0024 0.0027 0.5
Echinococcus multilocularis tissue type plasminogen activator 0.0045 0.0164 0.0164
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0009 0.0009
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0027 0.0027
Toxoplasma gondii peptidase family M13 protein 0.0093 0.0484 0.0484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Schistosoma mansoni neuronal calcium sensor 0.0054 0.0228 0.0228
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0276 0.17 0.17
Loa Loa (eye worm) hypothetical protein 0.1048 0.6827 0.6827
Schistosoma mansoni microtubule-associated protein tau 0.1432 0.9383 0.9383
Trypanosoma cruzi major cysteine proteinase, putative 0.0247 0.1511 0.1511
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.015 0.0863 0.1839
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0127 0.0709 0.0684
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Entamoeba histolytica cysteine protease, putative 0.015 0.0863 0.2064
Plasmodium falciparum peptidase, putative 0.0185 0.1097 0.2576
Plasmodium falciparum serine repeat antigen 8 0.015 0.0863 0.2012
Brugia malayi Animal haem peroxidase family protein 0.0063 0.029 0.029
Leishmania major proteasome beta 2 subunit, putative 0.0041 0.014 0.0113
Onchocerca volvulus Peroxidase homolog 0.0063 0.029 0.029
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0132 0.0132
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0066 0.0307 0.0307
Schistosoma mansoni rab 0.0054 0.0228 0.0228
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0036 0.011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0657 0.0657
Trichomonas vaginalis calpain, putative 0.0119 0.0657 0.1401
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.015 0.0863 0.2012
Echinococcus multilocularis neuronal calcium sensor 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0091 0.0471 0.0471
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0054 0.0228 0.0546
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.015 0.0863 0.1839
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2493
Echinococcus granulosus microtubule associated protein 2 0.1432 0.9383 0.9383
Leishmania major centrin, putative 0.0054 0.0228 0.0201
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1048 0.6827 0.6827
Echinococcus multilocularis EF hand domain containing family member A2 0.0054 0.0228 0.0228
Leishmania major cathepsin L-like protease 0.0747 0.4829 0.4815
Onchocerca volvulus Cathepsin L homolog 0.0649 0.418 0.418
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0127 0.0709 0.0709
Trypanosoma brucei calpain, putative 0.0119 0.0657 0.0631
Onchocerca volvulus Glycogen phosphorylase homolog 0.0106 0.0575 0.0575
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0173 0.0167
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0054 0.0228 0.0486
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0517 0.3305 0.3305
Onchocerca volvulus 0.0139 0.079 0.079
Schistosoma mansoni flap endonuclease-1 0.0023 0.002 0.002
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0132 0.0132
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0009 0.0009
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0085 0.0433 0.0407
Brugia malayi Papain family cysteine protease containing protein 0.015 0.0863 0.0863
Loa Loa (eye worm) hypothetical protein 0.0093 0.0484 0.0484
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0638 0.4106 0.4106
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0119 0.0657 0.0631
Leishmania major hypothetical protein, conserved 0.0119 0.0657 0.0631
Toxoplasma gondii ABC1 family protein 0.0035 0.0099 0.0099
Onchocerca volvulus 0.0649 0.418 0.418
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Echinococcus granulosus calpain A 0.1102 0.7191 0.7191
Trypanosoma brucei centrin-3 0.0054 0.0228 0.0201
Plasmodium vivax serine-repeat antigen (SERA) 0.015 0.0863 0.2012
Onchocerca volvulus Prolyl endopeptidase homolog 0.1525 1 1
Onchocerca volvulus 0.0029 0.0059 0.0059
Trypanosoma cruzi oligopeptidase b 0.0623 0.4009 0.4009
Giardia lamblia Cathepsin L precursor 0.015 0.0863 0.261
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0395 0.2493 0.2493
Loa Loa (eye worm) glycogen phosphorylase 0.0106 0.0575 0.0575
Loa Loa (eye worm) papain family cysteine protease containing protein 0.015 0.0863 0.0863
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0649 0.418 0.418
Entamoeba histolytica calpain large subunit domain III containing protein 0.0276 0.1704 0.4076
Loa Loa (eye worm) calpain family protein 1 0.1048 0.6827 0.6827
Echinococcus multilocularis calmodulin 0.0054 0.0228 0.0228
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0054 0.0228 0.0228
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0055 0.0231 0.0231
Brugia malayi fibroinase precursor 0.015 0.0863 0.0863
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0132 0.0132
Mycobacterium ulcerans hypothetical protein 0.0139 0.079 0.1793
Plasmodium vivax vivapain-2 0.0649 0.418 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0099 0.0212
Trichomonas vaginalis calcineurin B subunit, putative 0.0055 0.0231 0.0493
Brugia malayi beta-lactamase family protein 0.0035 0.0099 0.0099
Trypanosoma brucei centrin, putative 0.0054 0.0228 0.0201
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0467 0.0467
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0575 0.0575
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0284 0.1753 0.1753
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0027 0.0027
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0009 0.0009
Onchocerca volvulus Chorion peroxidase homolog 0.0063 0.029 0.029
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0059 0.0059
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.015 0.0863 0.261
Entamoeba histolytica cysteine proteinase, putative 0.0649 0.418 1
Echinococcus multilocularis calbindin 32 0.0055 0.0231 0.0231
Schistosoma mansoni caspase-7 (C14 family) 0.0638 0.4106 0.4106
Echinococcus granulosus caspase 2 0.0506 0.3232 0.3232
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.02 0.02
Entamoeba histolytica grainin 2 0.0054 0.0228 0.0546
Brugia malayi Animal haem peroxidase family protein 0.0063 0.029 0.029
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0575 0.0575
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0132 0.0282
Mycobacterium ulcerans transglutaminase family protein 0.0035 0.0098 0.003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0066 0.0307 0.0281
Giardia lamblia Alanyl dipeptidyl peptidase 0.0185 0.1097 0.3319
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Loa Loa (eye worm) cathepsin B 0.0517 0.3305 0.3305
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0099 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0185 0.1097 0.1097
Onchocerca volvulus 0.0054 0.0228 0.0228
Brugia malayi beta-lactamase family protein 0.0035 0.0099 0.0099
Schistosoma mansoni cpg binding protein 0.003 0.0068 0.0068
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0649 0.418 0.418
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0185 0.1097 0.2339
Echinococcus granulosus expressed protein 0.0775 0.5015 0.5015
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0467 0.0467
Toxoplasma gondii cathepsin B 0.0517 0.3305 0.3305
Brugia malayi Animal haem peroxidase family protein 0.0063 0.029 0.029
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.015 0.0863 0.1839
Schistosoma mansoni ef hand domain family member A2 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0035 0.0099 0.0099
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0132 0.0132
Echinococcus granulosus cathepsin l1 0.0649 0.418 0.418
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0119 0.0657 0.0657
Loa Loa (eye worm) hypothetical protein 0.0139 0.079 0.079
Loa Loa (eye worm) hypothetical protein 0.0045 0.0164 0.0164
Entamoeba histolytica cysteine protease, putative 0.015 0.0863 0.2064
Loa Loa (eye worm) hypothetical protein 0.0069 0.0323 0.0323
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0047 0.0179 0.0179
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0132 0.0132
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0027 0.0027
Schistosoma mansoni neuronal calcium sensor 0.0054 0.0228 0.0228
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Brugia malayi Trypsin family protein 0.0139 0.079 0.079
Mycobacterium ulcerans zinc metalloprotease 0.0093 0.0484 0.1014
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0185 0.1097 0.1097
Loa Loa (eye worm) hypothetical protein 0.0054 0.0228 0.0228
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0296 0.1833 0.1833
Schistosoma mansoni hypothetical protein 0.0045 0.0164 0.0164
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Loa Loa (eye worm) hypothetical protein 0.0284 0.1753 0.1753
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.0018 0.0018
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Onchocerca volvulus 0.0029 0.0059 0.0059
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Loa Loa (eye worm) beta-lactamase 0.0035 0.0099 0.0099
Echinococcus granulosus centrin 2 0.0054 0.0228 0.0228
Brugia malayi cathepsin L-like precursor 0.0447 0.2835 0.2835
Trypanosoma cruzi cysteine peptidase, putative 0.0747 0.4829 0.4829
Mycobacterium ulcerans lipase LipD 0.0035 0.0099 0.0034
Echinococcus granulosus tissue type plasminogen activator 0.0045 0.0164 0.0164
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0132 0.0132
Schistosoma mansoni coup transcription factor 0.0021 0.0009 0.0009
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0709 0.0709
Brugia malayi Cathepsin L-like precursor 0.0447 0.2835 0.2835
Echinococcus granulosus apoptotic protease activating factor 1 0.0223 0.1346 0.1346
Giardia lamblia Dipeptidyl-peptidase I precursor 0.015 0.0863 0.261
Loa Loa (eye worm) hypothetical protein 0.0035 0.0099 0.0099
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.015 0.0863 0.0863
Trypanosoma cruzi cysteine peptidase, putative 0.0747 0.4829 0.4829
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0119 0.0657 0.1401
Giardia lamblia Cathepsin B precursor 0.0517 0.3305 1
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0479 0.0479
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0068 0.0068
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0651 0.0651
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0009 0.0009
Onchocerca volvulus 0.0029 0.0059 0.0059
Onchocerca volvulus Cathepsin L homolog 0.0649 0.418 0.418
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1338 0.8759 0.8759
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0447 0.2835 0.6046
Entamoeba histolytica cysteine protease, putative 0.0649 0.418 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.0484 0.0484
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0575 0.1226
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0009 0.0009
Trypanosoma brucei calpain-like protein, putative 0.0395 0.2493 0.2472
Loa Loa (eye worm) hypothetical protein 0.0506 0.3232 0.3232
Loa Loa (eye worm) DEAH box polypeptide 35 0.0063 0.0288 0.0288
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0657 0.0657
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0066 0.0307 0.0307
Echinococcus granulosus cathepsin l1 0.0447 0.2835 0.2835
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Echinococcus multilocularis acylamino acid releasing enzyme 0.0185 0.1097 0.1097
Loa Loa (eye worm) hypothetical protein 0.0139 0.079 0.079
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.015 0.0863 0.2012
Schistosoma mansoni hypothetical protein 0.005 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0352 0.2207 0.2207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.015 0.0863 0.1839
Schistosoma mansoni neprilysin-2 (M13 family) 0.0047 0.0179 0.0179
Toxoplasma gondii cathepsin CPC2 0.015 0.0863 0.0863
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0009 0.0009
Trichomonas vaginalis hypothetical protein 0.0119 0.0657 0.1401
Mycobacterium ulcerans putative transglutaminase-like protein 0.0035 0.0098 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0517 0.3305 0.7047
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0059 0.0059
Entamoeba histolytica hypothetical protein 0.015 0.0863 0.2064
Toxoplasma gondii prolyl endopeptidase 0.1525 1 1
Loa Loa (eye worm) hypothetical protein 0.0223 0.1346 0.1346
Toxoplasma gondii centrin, putative 0.0054 0.0228 0.0228
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0276 0.17 0.1677
Loa Loa (eye worm) fibroinase 0.0649 0.418 0.418
Trypanosoma brucei protein I/6 0.0054 0.0228 0.0201
Mycobacterium ulcerans hypothetical protein 0.0035 0.0099 0.0034
Entamoeba histolytica calmodulin, putative 0.0054 0.0228 0.0546
Onchocerca volvulus 0.0649 0.418 0.418
Leishmania major calpain family cysteine protease-like protein 0.0119 0.0657 0.0631
Toxoplasma gondii microneme protein, putative 0.0029 0.0059 0.0059
Trichomonas vaginalis calcium binding protein, putative 0.0054 0.0228 0.0486
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0085 0.0433 0.0433
Entamoeba histolytica prolyl oligopeptidase family protein 0.0185 0.1097 0.2624
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1102 0.7187 0.7187
Mycobacterium leprae probable zinc metalloprotease 0.0093 0.0484 0.0986
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0041 0.014 0.014
Onchocerca volvulus 0.0726 0.4691 0.4691
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0132 0.0132
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0045 0.0164 0.0329
Brugia malayi Probable ATP-dependent helicase DHX35 0.0063 0.0288 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.015 0.0863 0.1839
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0009 0.0009
Onchocerca volvulus 0.0223 0.1346 0.1346
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0709 0.1588
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.0649 0.418 0.418
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0119 0.0657 0.0657
Leishmania major cathepsin L-like protease 0.0649 0.418 0.4164
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0139 0.079 0.079
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0479 0.0479
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0173 0.0415
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.1753 0.3739
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.015 0.0863 0.2012
Echinococcus multilocularis cathepsin L 0.015 0.0863 0.0863
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0132
Onchocerca volvulus 0.0649 0.418 0.418
Plasmodium vivax hypothetical protein, conserved 0.0185 0.1097 0.2576
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0709 0.1588
Giardia lamblia Cathepsin B precursor 0.0517 0.3305 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0098 0.0081
Plasmodium vivax centrin-1, putative 0.0054 0.0228 0.0484
Schistosoma mansoni neuronal calcium sensor 0.0054 0.0228 0.0228
Echinococcus granulosus cathepsin L cysteine proteinase 0.0649 0.418 0.418
Brugia malayi Protein kinase domain containing protein 0.0045 0.0164 0.0164
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0054 0.0228 0.0486
Loa Loa (eye worm) hypothetical protein 0.0138 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0093 0.0484 0.0484
Echinococcus multilocularis enteropeptidase 0.0139 0.079 0.079
Brugia malayi hypothetical protein 0.004 0.0132 0.0132
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0085 0.0433 0.0433
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.0018 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0709 0.0709
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Brugia malayi PXA domain containing protein 0.004 0.0132 0.0132
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0231 0.0492
Brugia malayi calpain family protein 1 0.1048 0.6827 0.6827
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0041 0.014 0.014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0395 0.2493 0.2493
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0638 0.4106 0.4106
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0132 0.0282
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1338 0.8759 0.8759
Toxoplasma gondii cathepsin CPC1 0.015 0.0863 0.0863
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0651 0.0651
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Trypanosoma cruzi calmodulin, putative 0.0054 0.0228 0.0228
Brugia malayi Cathepsin L-like precursor 0.0649 0.418 0.418
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0066 0.0307 0.0674
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0479 0.0479
Brugia malayi Trypsin family protein 0.0139 0.079 0.079
Trichomonas vaginalis calcium binding protein, putative 0.0054 0.0228 0.0486
Loa Loa (eye worm) calpain 5 0.0276 0.1704 0.1704
Brugia malayi cathepsin Z-like cysteine proteinase 0.015 0.0863 0.0863
Loa Loa (eye worm) hypothetical protein 0.007 0.0334 0.0334
Onchocerca volvulus 0.0054 0.0228 0.0228
Echinococcus granulosus cathepsin L cysteine protease 0.0352 0.2207 0.2207
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Schistosoma mansoni regulator of G protein signaling 0.004 0.0132 0.0132
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0649 0.418 0.418
Entamoeba histolytica cysteine protease, putative 0.015 0.0863 0.2064
Echinococcus granulosus calumenin 0.0055 0.0231 0.0231
Toxoplasma gondii EF hand domain-containing protein 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.015 0.0863 0.0863
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0099 0.0083
Plasmodium falciparum serine repeat antigen 4 0.015 0.0863 0.2012
Schistosoma mansoni caspase-7 (C14 family) 0.0506 0.3232 0.3232
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.015 0.0863 0.0863
Entamoeba histolytica hypothetical protein, conserved 0.0055 0.0231 0.0553
Brugia malayi Animal haem peroxidase family protein 0.0063 0.029 0.029
Echinococcus multilocularis Mastin 0.0139 0.079 0.079
Loa Loa (eye worm) trypsin family protein 0.0139 0.079 0.079
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0467 0.0467
Plasmodium vivax unspecified product 0.0352 0.2207 0.525
Echinococcus multilocularis inhibitor of apoptosis protein 0.0138 0.0781 0.0781
Schistosoma mansoni mitochondrial solute carrier 0.0054 0.0228 0.0228
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Echinococcus granulosus gamma secretase subunit aph 1 0.0296 0.1833 0.1833
Plasmodium falciparum metacaspase 1 0.0284 0.1753 0.4157
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0119 0.0657 0.0657
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0099 0.0099
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0018 0.0018
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0027 0.0027
Echinococcus multilocularis calpain 7 (C02 family) 0.0395 0.2493 0.2493
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Loa Loa (eye worm) proteasome subunit beta type 1 0.0066 0.0307 0.0307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.015 0.0863 0.1839
Echinococcus granulosus prolyl endopeptidase 0.1525 1 1
Echinococcus granulosus axis inhibition protein axin 0.004 0.0132 0.0132
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Echinococcus multilocularis endothelin converting enzyme 1 0.0093 0.0484 0.0484
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Schistosoma mansoni regulator of G protein signaling 0.004 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0202 0.1213 0.1213
Giardia lamblia Cysteine protease 0.015 0.0863 0.261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Echinococcus multilocularis calumenin 0.0055 0.0231 0.0231
Plasmodium falciparum serine repeat antigen 2 0.015 0.0863 0.2012
Trypanosoma brucei Metacaspase-4 0.0284 0.1753 0.1731
Trypanosoma brucei Calpain-like protein 1.1 0.0119 0.0657 0.0631
Trypanosoma cruzi metacaspase, putative 0.0284 0.1753 0.1753
Echinococcus granulosus cathepsin b 0.1338 0.8759 0.8759
Loa Loa (eye worm) hypothetical protein 0.015 0.0863 0.0863
Echinococcus multilocularis hypothetical protein 0.0395 0.2493 0.2493
Schistosoma mansoni regulator of G protein signaling 0.004 0.0132 0.0132
Mycobacterium tuberculosis Conserved protein 0.0035 0.0099 0.0083
Loa Loa (eye worm) hypothetical protein 0.007 0.0334 0.0334
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0054 0.0228 0.0201
Trichomonas vaginalis set domain proteins, putative 0.0726 0.469 1
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0009 0.0009
Schistosoma mansoni caspase-3 (C14 family) 0.0638 0.4106 0.4106
Trypanosoma brucei metacaspase MCA3 0.0284 0.1753 0.1731
Leishmania major cytochrome p450-like protein 0.0033 0.0086 0.0059
Plasmodium vivax serine-repeat antigen (SERA), putative 0.015 0.0863 0.2012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0323 0.0323
Trypanosoma cruzi Aph-1 protein, putative 0.0115 0.0633 0.0633
Schistosoma mansoni cathepsin F (C01 family) 0.0649 0.418 0.418
Mycobacterium tuberculosis Long conserved protein 0.0035 0.0098 0.0081
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0059 0.0059
Trypanosoma brucei Calpain-like protein 1.2 0.0119 0.0657 0.0631
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Entamoeba histolytica cysteine proteinase, putative 0.0352 0.2207 0.5281
Loa Loa (eye worm) hypothetical protein 0.0139 0.079 0.079
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0066 0.0307 0.0734
Leishmania major phospholipase c-like protein 0.0054 0.0228 0.0201
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0009 0.0009
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0575 0.1226
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0352 0.2207 0.4707
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.015 0.0863 0.0863
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0575 0.0575
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0059 0.0059
Brugia malayi nuclear hormone receptor 0.0021 0.0009 0.0009
Brugia malayi cathepsin F-like cysteine proteinase 0.015 0.0863 0.0863
Brugia malayi ecdysteroid receptor 0.0021 0.0009 0.0009
Toxoplasma gondii microneme protein MIC4 0.0029 0.0059 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.015 0.0863 0.1839
Schistosoma mansoni hypothetical protein 0.0139 0.079 0.079
Trypanosoma brucei Calpain-like protein 2 0.0119 0.0657 0.0631
Brugia malayi cathepsin F-like cysteine proteinase 0.0202 0.1213 0.1213
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0467 0.0467
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0649 0.418 0.418
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0649 0.418 0.8913
Schistosoma mansoni reticulocalbin 0.0054 0.0228 0.0228
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0623 0.4009 1
Brugia malayi Cathepsin L-like precursor 0.0649 0.418 0.418
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0099 0.0083
Loa Loa (eye worm) hypothetical protein 0.007 0.0334 0.0334
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1338 0.8759 0.8759
Brugia malayi Pre-SET motif family protein 0.0092 0.0479 0.0479
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0099 0.0174
Loa Loa (eye worm) hypothetical protein 0.007 0.0334 0.0334
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0623 0.4009 0.3993
Onchocerca volvulus 0.0652 0.4202 0.4202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2472
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0173 0.0415
Entamoeba histolytica calmodulin, putative 0.0054 0.0228 0.0546
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0119 0.0657 0.0657
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0132 0.0132
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0086 0.0059
Trypanosoma cruzi cruzipain precursor, putative 0.0202 0.1213 0.1213
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0276 0.17 0.17
Plasmodium vivax vivapain-3 0.0352 0.2207 0.525
Echinococcus multilocularis centrin 2 0.0054 0.0228 0.0228
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.0479 0.0479
Toxoplasma gondii centrin 0.0054 0.0228 0.0228
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0132 0.0132
Entamoeba histolytica cysteine proteinase 1, putative 0.0352 0.2207 0.5281
Trypanosoma cruzi hypothetical protein, conserved 0.0185 0.1097 0.1097
Loa Loa (eye worm) hypothetical protein 0.0245 0.1497 0.1497
Toxoplasma gondii EFHC1, putative 0.0054 0.0228 0.0228
Mycobacterium tuberculosis Probable peptidase 0.0623 0.4009 0.4554
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0009 0.0009
Echinococcus granulosus caspase 8 0.0284 0.1753 0.1753
Schistosoma mansoni cpg binding protein 0.0032 0.0079 0.0079
Plasmodium falciparum serine repeat antigen 9 0.015 0.0863 0.2012
Brugia malayi beta-lactamase 0.0035 0.0099 0.0099
Trypanosoma cruzi cysteine proteinase, putative 0.0352 0.2207 0.2207
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0036 0.0036
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.051 0.3258 0.3258
Trichomonas vaginalis conserved hypothetical protein 0.0185 0.1097 0.2339
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0544 0.3484 0.3484
Toxoplasma gondii aldehyde dehydrogenase 0.0127 0.0709 0.0709
Schistosoma mansoni peroxidasin 0.0063 0.029 0.029
Onchocerca volvulus Cathepsin L homolog 0.015 0.0863 0.0863
Onchocerca volvulus 0.0649 0.418 0.418
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0352 0.2207 0.2207
Trypanosoma brucei I/6 autoantigen 0.0054 0.0228 0.0201
Entamoeba histolytica cysteine protease, putative 0.015 0.0863 0.2064
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Onchocerca volvulus 0.0139 0.079 0.079
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0185 0.1097 0.1097
Echinococcus multilocularis peroxidasin 0.0063 0.029 0.029
Giardia lamblia Cathepsin L precursor 0.015 0.0863 0.261
Brugia malayi Trypsin-like protease protein 5 0.0139 0.079 0.079
Toxoplasma gondii kringle domain-containing protein 0.0045 0.0164 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.1753 0.3739
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Onchocerca volvulus 0.0029 0.0059 0.0059
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0323 0.0323
Echinococcus granulosus calpain 5 0.0395 0.2493 0.2493
Plasmodium falciparum metacaspase-like protein 0.0284 0.1753 0.4157
Entamoeba histolytica hypothetical protein 0.004 0.0132 0.0316
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0185 0.1097 0.1097
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Schistosoma mansoni neuronal calcium sensor 0.0054 0.0228 0.0228
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0036 0.0009
Echinococcus multilocularis calmodulin 0.0054 0.0228 0.0228
Loa Loa (eye worm) calmodulin-like protein 0.0054 0.0228 0.0228
Schistosoma mansoni peroxidasin 0.0063 0.029 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.015 0.0863 0.1839
Onchocerca volvulus 0.0649 0.418 0.418
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0009 0.0009
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0009 0.0009
Echinococcus granulosus dnaJ subfamily B 0.0428 0.2714 0.2714
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0099 0.0099
Echinococcus granulosus acylamino acid releasing enzyme 0.0185 0.1097 0.1097
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0132 0.0132
Onchocerca volvulus 0.0063 0.029 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Echinococcus multilocularis cpg binding protein 0.0032 0.0079 0.0079
Trypanosoma cruzi cruzipain precursor, putative 0.0747 0.4829 0.4829
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0009 0.0009
Toxoplasma gondii proteasome subunit beta type, putative 0.0085 0.0433 0.0433
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0276 0.17 0.17
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Giardia lamblia Transglutaminase/protease, putative 0.0035 0.0098 0.0296
Mycobacterium ulcerans beta-lactamase 0.0035 0.0099 0.0034
Echinococcus granulosus Glycosyl transferase family 35 0.0106 0.0575 0.0575
Echinococcus multilocularis dnaJ subfamily B 0.0428 0.2714 0.2714
Trypanosoma brucei calpain, putative 0.0119 0.0657 0.0631
Giardia lamblia Hypothetical protein 0.0055 0.0231 0.07
Entamoeba histolytica cysteine proteinase, putative 0.0447 0.2835 0.6783
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.014 0.014
Loa Loa (eye worm) programmed cell death protein 6 0.0055 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0099 0.0099
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0027 0.0027
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0054 0.0228 0.0484
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1525 1 1
Plasmodium falciparum serine repeat antigen 6 0.015 0.0863 0.2012
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0276 0.17 0.1677
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.1753 0.3739
Schistosoma mansoni axis inhibition protein axin 0.004 0.0132 0.0132
Plasmodium vivax unspecified product 0.0202 0.1213 0.2855
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.015 0.0863 0.1839
Echinococcus granulosus calpain A 0.0395 0.2493 0.2493
Onchocerca volvulus 0.0052 0.0212 0.0212
Trypanosoma brucei hypothetical protein 0.0119 0.0657 0.0631
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Leishmania major i/6 autoantigen-like protein 0.0054 0.0228 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0228 0.0486
Brugia malayi Proteasome A-type and B-type family protein 0.0085 0.0433 0.0433
Trypanosoma cruzi oligopeptidase b 0.0623 0.4009 0.4009
Echinococcus granulosus Mastin 0.0139 0.079 0.079
Brugia malayi Cathepsin L-like precursor 0.0649 0.418 0.418
Onchocerca volvulus 0.0092 0.0479 0.0479
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0467 0.0467
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0054 0.0228 0.0546
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.1753 0.3739
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0623 0.4009 0.4009
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0132
Brugia malayi Flap endonuclease-1 0.0025 0.0036 0.0036
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0623 0.4009 0.4009
Leishmania major calcineurin B subunit, putative 0.0054 0.0228 0.0201
Onchocerca volvulus 0.003 0.0068 0.0068
Echinococcus multilocularis transmembrane protease serine 3 0.0139 0.079 0.079
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0649 0.418 0.418
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0132 0.0132
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Leishmania major centrin, putative,caltractin, putative 0.0054 0.0228 0.0201
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Trypanosoma brucei Calpain-like protein CALP1.3 0.0119 0.0657 0.0631
Trichomonas vaginalis myosin light chain 1, putative 0.0054 0.0228 0.0486
Toxoplasma gondii calmodulin CAM1 0.0055 0.0231 0.0231
Plasmodium vivax serine-repeat antigen (SERA), putative 0.015 0.0863 0.2012
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0041 0.014 0.014
Brugia malayi Pre-SET motif family protein 0.0638 0.4105 0.4105
Schistosoma mansoni reticulocalbin 0.0055 0.0231 0.0231
Plasmodium vivax proteasome subunit beta type-5, putative 0.0085 0.0433 0.0977
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Brugia malayi cahepsin L-like non-peptiedase homolog 0.015 0.0863 0.0863
Onchocerca volvulus Peroxidase homolog 0.0063 0.029 0.029
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0185 0.1097 0.1097
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0009 0.0009
Echinococcus multilocularis Transglutaminase 0.0035 0.0098 0.0098
Entamoeba histolytica calcium binding family protein 0.0054 0.0228 0.0546
Trichomonas vaginalis peptide N-glycanase, putative 0.0035 0.0098 0.0209
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Plasmodium vivax vivapain-1 0.0352 0.2207 0.525
Brugia malayi cathepsin Z-like cysteine proteinase 0.015 0.0863 0.0863
Trypanosoma cruzi prolyl endopeptidase 0.1525 1 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0649 0.418 1
Onchocerca volvulus 0.0063 0.029 0.029
Plasmodium vivax calpain, putative 0.0395 0.2493 0.5938
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0036 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.007 0.0334 0.0334
Plasmodium vivax metacaspase 1, putative 0.0284 0.1753 0.4157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0036 0.0009
Loa Loa (eye worm) hypothetical protein 0.007 0.0334 0.0334
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.015 0.0863 0.2012
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.014 0.0298
Echinococcus multilocularis cathepsin b 0.1338 0.8759 0.8759
Loa Loa (eye worm) blistered cuticle protein 3 0.0063 0.029 0.029
Giardia lamblia Proteasome subunit beta type 1 0.0066 0.0307 0.0929
Leishmania major calpain protease-like protein 0.0119 0.0657 0.0631
Trypanosoma brucei antigen, putative 0.0395 0.2493 0.2472
Brugia malayi gamma-secretase subunit aph-1 0.0296 0.1833 0.1833
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0099 0.0099
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Brugia malayi hypothetical protein 0.0223 0.1346 0.1346
Echinococcus granulosus Dipeptidyl peptidase 9 0.0276 0.17 0.17
Schistosoma mansoni centrin 0.0054 0.0228 0.0228
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0657 0.0657
Leishmania major protein kinase, putative 0.0054 0.0228 0.0201
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0027 0.0058
Loa Loa (eye worm) hypothetical protein 0.015 0.0863 0.0863
Trypanosoma brucei mitochondrial calcium uptake 1 0.0054 0.0228 0.0201
Echinococcus granulosus endothelin converting enzyme 1 0.0093 0.0484 0.0484
Brugia malayi proteasome subunit beta type 1 0.0066 0.0307 0.0307
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0202 0.1213 0.1213
Trypanosoma brucei calmodulin, putative 0.0055 0.0231 0.0205
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0009 0.0009
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.015 0.0863 0.2012
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0139 0.079 0.079
Toxoplasma gondii cathepsin CPL 0.0649 0.418 0.418
Toxoplasma gondii hypothetical protein 0.0185 0.1097 0.1097
Echinococcus granulosus neuronal calcium sensor 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0138 0.0781 0.0781
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0623 0.4009 0.4554
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0467 0.0467
Onchocerca volvulus 0.0029 0.0059 0.0059
Mycobacterium tuberculosis Hypothetical protein 0.0035 0.0098 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0099 0.0212
Plasmodium vivax unspecified product 0.015 0.0863 0.2012
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0649 0.418 1
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0009 0.0009
Leishmania major metacaspase, putative 0.0284 0.1753 0.1731
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0036 0.0036
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0119 0.0657 0.0631
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0132 0.0282
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.051 0.3258 0.3258
Trichomonas vaginalis calcium binding protein, putative 0.0054 0.0228 0.0486
Onchocerca volvulus 0.0649 0.418 0.418
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0009 0.0009
Loa Loa (eye worm) calpain 0.0395 0.2493 0.2493
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.015 0.0863 0.0863
Brugia malayi Cathepsin L-like precursor 0.0649 0.418 0.418
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0009 0.0009
Leishmania major calmodulin-like protein 0.0054 0.0228 0.0201
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0085 0.0433 0.1036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0447 0.2835 0.6046
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Loa Loa (eye worm) hypothetical protein 0.0092 0.0479 0.0479
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Onchocerca volvulus 0.0029 0.0059 0.0059
Entamoeba histolytica grainin, putative 0.0055 0.0231 0.0553
Onchocerca volvulus 0.015 0.0863 0.0863
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0202 0.1213 0.1213
Brugia malayi hypothetical protein 0.0245 0.1497 0.1497
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0046 0.0173 0.0173
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0138 0.0781 0.0781
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.015 0.0863 0.2012
Plasmodium vivax proteasome subunit beta type-1, putative 0.0066 0.0307 0.0674
Trypanosoma cruzi Aph-1 protein, putative 0.0115 0.0633 0.0633
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.051 0.3258 0.3258
Onchocerca volvulus Cathepsin F homolog 0.0649 0.418 0.418
Brugia malayi programmed cell death protein 6 0.0054 0.0228 0.0228
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0086 0.0086
Echinococcus granulosus transmembrane protease serine 3 0.0139 0.079 0.079
Leishmania major cathepsin L-like protease 0.0649 0.418 0.4164
Mycobacterium leprae Probable lipase LipE 0.0035 0.0099 0.0004
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Leishmania major kinesin, putative 0.0276 0.1704 0.1681
Trypanosoma brucei cysteine peptidase, putative 0.0119 0.0657 0.0631
Loa Loa (eye worm) proteasome subunit beta type 2 0.0041 0.014 0.014
Echinococcus granulosus cathepsin L 0.015 0.0863 0.0863
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0575 0.1375
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0054 0.0228 0.0228
Echinococcus multilocularis calpain 0.0395 0.2493 0.2493
Plasmodium vivax serine-repeat antigen (SERA) 0.015 0.0863 0.2012
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0086 0.0086
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0085 0.0433 0.0433
Brugia malayi Cathepsin L-like precursor 0.0649 0.418 0.418
Brugia malayi Trypsin family protein 0.0139 0.079 0.079
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0132 0.0132
Trypanosoma brucei prolyl endopeptidase 0.1525 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Brugia malayi prolyl oligopeptidase family protein 0.0185 0.1097 0.1097
Entamoeba histolytica cysteine proteinase 2 0.0352 0.2207 0.5281
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0395 0.2493 0.2493
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0132 0.0132
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0085 0.0433 0.0857
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0228 0.0486
Schistosoma mansoni regulator of G protein signaling 0.004 0.0132 0.0132
Leishmania major programmed cell death 6 protein-like protein 0.0054 0.0228 0.0201
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1525 1 1
Loa Loa (eye worm) hypothetical protein 0.015 0.0863 0.0863
Onchocerca volvulus 0.0035 0.0099 0.0099
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0099 0.0083
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0054 0.0228 0.0228
Echinococcus multilocularis survival motor neuron protein 1 0.0245 0.1497 0.1497
Echinococcus granulosus cathepsin L 0.0352 0.2207 0.2207
Trypanosoma cruzi kinesin, putative 0.0276 0.1704 0.1704
Giardia lamblia Hypothetical protein 0.015 0.0863 0.261
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2472
Loa Loa (eye worm) hypothetical protein 0.015 0.0863 0.0863
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Loa Loa (eye worm) hypothetical protein 0.0159 0.0921 0.0921
Onchocerca volvulus 0.0159 0.0921 0.0921
Echinococcus granulosus enteropeptidase 0.0139 0.079 0.079
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0027 0.0058
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0009 0.0009
Echinococcus multilocularis Glycosyl transferase, family 35 0.0106 0.0575 0.0575
Schistosoma mansoni hypothetical protein 0.0035 0.0098 0.0098
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Echinococcus granulosus cathepsin b 0.1338 0.8759 0.8759
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0371 0.233 0.233
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.015 0.0863 0.0863
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0059 0.0059
Echinococcus granulosus EF HAND 1 calcium binding site 0.0054 0.0228 0.0228
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0132 0.0132
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0059 0.0059
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0009 0.0009
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0099 0.0004
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0027 0.0082
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0093 0.0484 0.0484
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0099 0.0083
Echinococcus granulosus EF hand domain containing family member A2 0.0054 0.0228 0.0228
Echinococcus multilocularis EF hand domain containing family member A2 0.0055 0.0231 0.0231
Entamoeba histolytica cysteine protease, putative 0.015 0.0863 0.2064
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Trichomonas vaginalis calcium binding protein, putative 0.0054 0.0228 0.0486
Brugia malayi calpain 5 0.0119 0.0657 0.0657
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0132 0.0132
Echinococcus granulosus flap endonuclease 1 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0185 0.1097 0.2624
Trypanosoma brucei cysteine peptidase C (CPC) 0.0517 0.3305 0.3287
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0179 0.0179
Schistosoma mansoni axis inhibition protein axin 0.004 0.0132 0.0132
Echinococcus multilocularis programmed cell death protein 0.0054 0.0228 0.0228
Plasmodium falciparum serine repeat antigen 3 0.015 0.0863 0.2012
Loa Loa (eye worm) hypothetical protein 0.0652 0.4202 0.4202
Toxoplasma gondii hypothetical protein 0.0029 0.0059 0.0059
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0041 0.014 0.014
Trypanosoma cruzi cysteine proteinase, putative 0.0352 0.2207 0.2207
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0352 0.2207 0.2207
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0099 0.0099
Schistosoma mansoni calpain-7 (C02 family) 0.0395 0.2493 0.2493
Brugia malayi calpain family protein 1 0.1048 0.6827 0.6827
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0009 0.0009
Schistosoma mansoni calmodulin 0.0054 0.0228 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.015 0.0863 0.1839
Brugia malayi EF hand family protein 0.0054 0.0228 0.0228
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0132
Schistosoma mansoni calpain C (C02 family) 0.0395 0.2493 0.2493
Entamoeba histolytica cysteine proteinase, putative 0.0352 0.2207 0.5281
Leishmania major cysteine peptidase A (CPA) 0.0649 0.418 0.4164
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0041 0.014 0.0271
Onchocerca volvulus 0.0447 0.2835 0.2835
Mycobacterium ulcerans hypothetical protein 0.0035 0.0098 0.003
Toxoplasma gondii subtilisin SUB12 0.0029 0.0059 0.0059
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0099 0.0099
Plasmodium falciparum flap endonuclease 1 0.0025 0.0036 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0009 0.0009
Chlamydia trachomatis glycogen phosphorylase 0.0106 0.0575 0.5
Mycobacterium ulcerans hypothetical protein 0.0035 0.0098 0.003
Loa Loa (eye worm) hypothetical protein 0.1525 1 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0288 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0863 0.1839
Giardia lamblia Cathepsin B precursor 0.015 0.0863 0.261
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0009 0.0009
Onchocerca volvulus 0.0139 0.079 0.079
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2493
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Trichomonas vaginalis centrin, putative 0.0054 0.0228 0.0486
Loa Loa (eye worm) hypothetical protein 0.0139 0.079 0.079
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0185 0.1097 0.1073
Brugia malayi nuclear receptor NHR-88 0.0021 0.0009 0.0009
Giardia lamblia Cathepsin L-like protease 0.015 0.0863 0.261
Brugia malayi steroid hormone receptor 0.0021 0.0009 0.0009
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0085 0.0433 0.0433
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.015 0.0863 0.0863
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0132 0.0132
Brugia malayi Blistered cuticle protein 3 0.0063 0.029 0.029
Echinococcus granulosus EF hand domain containing family member A2 0.0055 0.0231 0.0231
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Entamoeba histolytica cysteine proteinase, putative 0.0352 0.2207 0.5281
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0479 0.0479
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0575 0.0575
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Giardia lamblia Hypothetical protein 0.0035 0.0098 0.0296
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0185 0.1097 0.2624
Mycobacterium tuberculosis Conserved protein 0.0035 0.0099 0.0083
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0164 0.0164
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.015 0.0863 0.2012
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0085 0.0433 0.0923
Echinococcus multilocularis cysteine protease 0.0649 0.418 0.418
Trypanosoma cruzi metacaspase, putative 0.0284 0.1753 0.1753
Trypanosoma cruzi centrin, putative 0.0054 0.0228 0.0228
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Trypanosoma cruzi calmodulin, putative 0.0054 0.0228 0.0228
Plasmodium falciparum serine repeat antigen 1 0.015 0.0863 0.2012
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0185 0.1097 0.1097
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.015 0.0863 0.2012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Echinococcus multilocularis programmed cell death protein 0.0054 0.0228 0.0228
Onchocerca volvulus 0.0029 0.0059 0.0059
Echinococcus multilocularis proteasome (prosome, macropain) 0.0085 0.0433 0.0433
Loa Loa (eye worm) hypothetical protein 0.0447 0.2835 0.2835
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0132 0.0132
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0009 0.0009
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0132 0.0132
Trypanosoma cruzi cysteine peptidase, putative 0.0649 0.418 0.418
Giardia lamblia Cathepsin B precursor 0.015 0.0863 0.261
Entamoeba histolytica papain family cysteine protease domain containing protein 0.015 0.0863 0.2064
Trypanosoma brucei calpain-like protein, putative 0.0395 0.2493 0.2472
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0099 0.0212
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0138 0.0781 0.0781
Echinococcus multilocularis microtubule associated protein 2 0.1432 0.9383 0.9383
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.015 0.0863 0.1839
Giardia lamblia Cathepsin L precursor 0.015 0.0863 0.261
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0132
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0132 0.0132
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0041 0.014 0.0113
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.0479 0.0479
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0009 0.0009
Trichomonas vaginalis calcium binding proteins, putative 0.0054 0.0228 0.0486
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0093 0.0484 0.0484
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1102 0.7187 0.7187
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0027 0.0027
Trypanosoma cruzi cysteine protease, putative 0.0352 0.2207 0.2207
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0119 0.0657 0.1401
Loa Loa (eye worm) hypothetical protein 0.0069 0.0323 0.0323
Plasmodium vivax SET domain protein, putative 0.0092 0.0479 0.1089
Schistosoma mansoni neprilysin 0.0024 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.015 0.0863 0.1839
Echinococcus granulosus Transglutaminase 0.0035 0.0098 0.0098
Leishmania major oligopeptidase b 0.0623 0.4009 0.3993
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0132
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Echinococcus multilocularis cathepsin L cysteine protease 0.0649 0.418 0.418
Mycobacterium ulcerans proteasome PrcB 0.0085 0.0433 0.0884
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1102 0.7187 0.7187
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0098 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0132 0.0132
Entamoeba histolytica cysteine proteinase, putative 0.0352 0.2207 0.5281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0009 0.0009
Echinococcus granulosus neurocalcin 0.0054 0.0228 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.1753 0.3739
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0179 0.0179
Echinococcus multilocularis gamma secretase subunit aph 1 0.0296 0.1833 0.1833
Entamoeba histolytica prolyl oligopeptidase family protein 0.0185 0.1097 0.2624
Loa Loa (eye worm) hypothetical protein 0.0035 0.0099 0.0099
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.015 0.0863 0.0863
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0575 0.0575
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0059 0.0059
Giardia lamblia Cathepsin L precursor 0.015 0.0863 0.261
Trypanosoma brucei caltractin, putative 0.0054 0.0228 0.0201
Plasmodium vivax vivapain-2 0.0649 0.418 1
Brugia malayi Papain family cysteine protease containing protein 0.0352 0.2207 0.2207
Echinococcus granulosus caspase 0.0638 0.4106 0.4106
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0276 0.17 0.17
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0036 0.0087
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0099 0.0099
Plasmodium falciparum centrin-1 0.0054 0.0228 0.0484
Brugia malayi Thioredoxin family protein 0.0035 0.0098 0.0098
Brugia malayi Kringle domain containing protein 0.0045 0.0164 0.0164
Schistosoma mansoni cathepsin s 0.0202 0.1213 0.1213
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1348 0.151
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0127 0.0709 0.0709
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0269 0.0269
Giardia lamblia Cysteine protease 0.015 0.0863 0.261
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1338 0.8759 0.8759
Toxoplasma gondii hypothetical protein 0.0029 0.0059 0.0059
Leishmania major hypothetical protein, unknown function 0.0119 0.0657 0.0631
Giardia lamblia Dipeptidyl-peptidase I precursor 0.015 0.0863 0.261
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0132 0.0282
Brugia malayi Papain family cysteine protease containing protein 0.015 0.0863 0.0863
Trypanosoma cruzi I/6 autoantigen, putative 0.0054 0.0228 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Trypanosoma cruzi metacaspase 5, putative 0.0284 0.1753 0.1753
Trichomonas vaginalis esterase, putative 0.0035 0.0099 0.0212
Brugia malayi Cytochrome P450 family protein 0.0054 0.0228 0.0228
Giardia lamblia Cathepsin B precursor 0.0517 0.3305 1
Onchocerca volvulus 0.0046 0.0173 0.0173
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0098 0.0081
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.015 0.0863 0.2012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Echinococcus multilocularis glycoprotein Antigen 5 0.0139 0.079 0.079
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0059 0.0059
Trypanosoma brucei metacaspase 5, putative 0.0284 0.1753 0.1731
Entamoeba histolytica cysteine proteinase, putative 0.0649 0.418 1
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0132 0.0132
Onchocerca volvulus 0.0021 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0009 0.0009
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0099 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.015 0.0863 0.1839
Leishmania major cathepsin L-like protease 0.0649 0.418 0.4164
Trypanosoma cruzi 20S proteasome subunit 0.0041 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0228 0.0228
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0307 0.0307
Plasmodium falciparum cysteine proteinase falcipain 1 0.0352 0.2207 0.525
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0371 0.233 0.233
Entamoeba histolytica cysteine protease, putative 0.015 0.0863 0.2064
Entamoeba histolytica hypothetical protein, conserved 0.0185 0.1097 0.2624
Brugia malayi prolyl oligopeptidase family protein 0.0185 0.1097 0.1097
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0452 0.0452
Schistosoma mansoni Mername-AA248 (C02 family) 0.0395 0.2493 0.2493
Giardia lamblia Cysteine protease 0.015 0.0863 0.261
Giardia lamblia Cysteine protease 0.015 0.0863 0.261
Echinococcus multilocularis apoptotic protease activating factor 1 0.0223 0.1346 0.1346
Onchocerca volvulus 0.005 0.02 0.02
Echinococcus multilocularis cathepsin L 0.0352 0.2207 0.2207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0132 0.0132
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0066 0.0307 0.0307
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0623 0.4009 0.3993
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0132 0.0282
Schistosoma mansoni cathepsin C 0.015 0.0863 0.0863
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0284 0.1753 0.1753
Brugia malayi Animal haem peroxidase family protein 0.0063 0.029 0.029
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0009 0.0009
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.029 0.029
Trypanosoma cruzi cysteine peptidase, putative 0.0352 0.2207 0.2207
Schistosoma mansoni inhibitor of apoptosis protein 0.0138 0.0781 0.0781
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0009 0.0009
Echinococcus granulosus calcium uptake protein 1 0.0055 0.0231 0.0231
Toxoplasma gondii hypothetical protein 0.0119 0.0657 0.0657
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0009 0.0009
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0467 0.0467
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0467 0.0467
Onchocerca volvulus 0.0045 0.0164 0.0164
Schistosoma mansoni hypothetical protein 0.0054 0.0228 0.0228
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0139 0.079 0.079
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0009 0.0009
Onchocerca volvulus 0.0035 0.0099 0.0099
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0099 0.0099
Entamoeba histolytica protein kinase, putative 0.0276 0.1704 0.4076
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0036 0.0036
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0395 0.2493 0.2493
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Entamoeba histolytica calcium-binding protein, putative 0.0054 0.0228 0.0546
Leishmania major cathepsin L-like protease 0.0649 0.418 0.4164
Onchocerca volvulus 0.0138 0.0781 0.0781
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0009 0.0009
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0027 0.0027
Onchocerca volvulus Cell death protein 3 homolog 0.0506 0.3232 0.3232
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Loa Loa (eye worm) cysteine protease 0.0649 0.418 0.418
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.015 0.0863 0.0863
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0099 0.0099
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0352 0.2207 0.2207
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Trypanosoma cruzi kinesin, putative 0.0276 0.1704 0.1704
Echinococcus granulosus tumor protein p63 0.0354 0.2223 0.2223
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0212 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.0747 0.4829 0.4829
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0575 0.1375
Loa Loa (eye worm) hypothetical protein 0.0052 0.0212 0.0212
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0132 0.0132
Echinococcus granulosus calpain 7 C02 family 0.0395 0.2493 0.2493
Loa Loa (eye worm) papain family cysteine protease containing protein 0.015 0.0863 0.0863
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.029 0.029
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0085 0.0433 0.0464
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0119 0.0657 0.0657
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0119 0.0657 0.0631
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Giardia lamblia Dipeptidyl-peptidase I precursor 0.015 0.0863 0.261
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2493
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0018 0.0018
Trypanosoma brucei hypothetical protein, conserved 0.0054 0.0228 0.0201
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0132 0.0132
Schistosoma mansoni hypothetical protein 0.0223 0.1346 0.1346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Trichomonas vaginalis calmodulin, putative 0.0055 0.0231 0.0493
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0054 0.0228 0.0228
Toxoplasma gondii calcium-dependent protein kinase 0.0055 0.0231 0.0231
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.0138 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.051 0.3258 0.3258
Echinococcus granulosus cysteine protease 0.0352 0.2207 0.2207
Schistosoma mansoni cathepsin F (C01 family) 0.0649 0.418 0.418
Brugia malayi carbohydrate phosphorylase 0.0106 0.0575 0.0575
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0009 0.0009
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0127 0.0709 0.078
Plasmodium falciparum calpain 0.0119 0.0657 0.1517
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0395 0.2493 0.2493
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0086 0.0086
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Trypanosoma cruzi conserved protein 0.0119 0.0657 0.0657
Echinococcus granulosus peroxidasin 0.0063 0.029 0.029
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0323 0.0323
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0657 0.0657
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Loa Loa (eye worm) hypothetical protein 0.0202 0.1213 0.1213
Brugia malayi Papain family cysteine protease containing protein 0.0352 0.2207 0.2207
Schistosoma mansoni hypothetical protein 0.0119 0.0657 0.0657
Brugia malayi PAN domain containing protein 0.0029 0.0059 0.0059
Echinococcus granulosus proteasome prosome macropain 0.0085 0.0433 0.0433
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0119 0.0657 0.1401
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0009 0.0009
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0395 0.2493 0.2493
Trypanosoma cruzi metacaspase 5, putative 0.0284 0.1753 0.1753
Giardia lamblia Glycogen phosphorylase 0.0106 0.0575 0.1739
Echinococcus granulosus axis inhibition protein axin 0.004 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0132 0.0282
Leishmania major calmodulin, putative 0.0054 0.0228 0.0201
Leishmania major cathepsin L-like protease 0.0747 0.4829 0.4815
Schistosoma mansoni gamma-secretase subunit aph-1 0.0296 0.1833 0.1833
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Schistosoma mansoni centrin-related 0.0054 0.0228 0.0228
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0119 0.0657 0.1401
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0352 0.2207 0.2186
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0119 0.0657 0.1401
Leishmania major cathepsin L-like protease 0.0747 0.4829 0.4815
Onchocerca volvulus Peroxidasin homolog 0.0063 0.029 0.029
Onchocerca volvulus 0.0139 0.079 0.079
Echinococcus granulosus calmodulin 0.0054 0.0228 0.0228
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0276 0.17 0.17
Trypanosoma brucei metacaspase MCA2 0.0284 0.1753 0.1731
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0709 0.1588
Giardia lamblia Hypothetical protein 0.015 0.0863 0.261
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Loa Loa (eye worm) hypothetical protein 0.0139 0.079 0.079
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0132 0.0132
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0811 0.5258 0.5258
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Brugia malayi EF hand family protein 0.0055 0.0231 0.0231
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0139 0.079 0.079
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1102 0.7187 0.7187
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0009 0.0009
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0179 0.0179
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0054 0.0228 0.0228
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0059 0.0059
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1525 1 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0284 0.1753 0.1753
Brugia malayi Cytochrome P450 family protein 0.0033 0.0086 0.0086
Brugia malayi calpain 7 0.0395 0.2493 0.2493
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Brugia malayi Peptidase family M13 containing protein 0.0093 0.0484 0.0484
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0093 0.0484 0.0522
Onchocerca volvulus 0.0139 0.079 0.079
Loa Loa (eye worm) ctsf protein 0.0649 0.418 0.418
Brugia malayi Trypsin family protein 0.0139 0.079 0.079
Echinococcus multilocularis calpain family protein 1, d 0.0771 0.4991 0.4991
Loa Loa (eye worm) hypothetical protein 0.015 0.0863 0.0863
Toxoplasma gondii preprocathepsin c precursor, putative 0.015 0.0863 0.0863
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0657 0.0657
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Echinococcus multilocularis calpain 5 0.0395 0.2493 0.2493
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0018 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.0202 0.1213 0.1213
Entamoeba histolytica hypothetical protein 0.004 0.0132 0.0316
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Leishmania major hypothetical protein, conserved 0.0035 0.0099 0.0072
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.029 0.029
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0132 0.0132
Schistosoma mansoni hypothetical protein 0.0139 0.079 0.079
Echinococcus multilocularis neurocalcin 0.0054 0.0228 0.0228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0649 0.418 0.8913
Giardia lamblia Cathepsin L precursor 0.015 0.0863 0.261
Giardia lamblia Encystation-specific protease 0.015 0.0863 0.261
Echinococcus multilocularis caspase 0.0638 0.4106 0.4106
Giardia lamblia Proteasome subunit beta type 2 0.0041 0.014 0.0423
Loa Loa (eye worm) hypothetical protein 0.0139 0.079 0.079
Brugia malayi Cathepsin L-like cysteine proteinase 0.0447 0.2835 0.2835
Onchocerca volvulus Dual oxidase homolog 0.0063 0.029 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.015 0.0863 0.1839
Onchocerca volvulus 0.0029 0.0059 0.0059
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.134 0.8771 1
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.029 0.029
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0059 0.0059
Schistosoma mansoni cpg binding protein 0.0032 0.0079 0.0079
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.0479 0.0479
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0055 0.0231 0.0231
Echinococcus granulosus inhibitor of apoptosis protein 0.0138 0.0781 0.0781
Schistosoma mansoni hypothetical protein 0.0428 0.2714 0.2714
Loa Loa (eye worm) hypothetical protein 0.0035 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.1753 0.3739
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0085 0.0433 0.131
Trypanosoma brucei prolyl oligopeptidase, putative 0.0623 0.4009 0.3993
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0747 0.4829 0.4815
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0009 0.0009
Onchocerca volvulus Peroxidasin homolog 0.0063 0.029 0.029
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0132 0.0132
Onchocerca volvulus 0.0139 0.079 0.079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0467 0.0467
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0009 0.0009
Brugia malayi MH2 domain containing protein 0.0118 0.0651 0.0651
Leishmania major calmodulin-like protein 0.0054 0.0228 0.0201
Schistosoma mansoni survival motor neuron protein 0.005 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Brugia malayi peptidase family M13 containing protein 0.0023 0.0018 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0099 0.0212
Giardia lamblia Alanyl dipeptidyl peptidase 0.0185 0.1097 0.3319
Trypanosoma brucei proteasome beta 6 subunit 0.0066 0.0307 0.0281
Giardia lamblia Cathepsin B precursor 0.015 0.0863 0.261
Trichomonas vaginalis calpain, putative 0.0119 0.0657 0.1401
Brugia malayi hypothetical protein 0.0139 0.079 0.079
Brugia malayi Papain family cysteine protease containing protein 0.015 0.0863 0.0863
Echinococcus multilocularis caspase 3 0.0354 0.222 0.222
Entamoeba histolytica papain family cysteine protease domain containing protein 0.015 0.0863 0.2064
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0173 0.0223
Leishmania major cathepsin L-like protease 0.0649 0.418 0.4164
Schistosoma mansoni calmodulin 0.0054 0.0228 0.0228
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.015 0.0863 0.1839
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0099 0.0072
Leishmania major centrin, putative 0.0054 0.0228 0.0201
Echinococcus granulosus caspase 3 0.0354 0.222 0.222
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0099 0.0083
Loa Loa (eye worm) prolyl oligopeptidase 0.0185 0.1097 0.1097
Brugia malayi cathepsin L precursor 0.015 0.0863 0.0863
Schistosoma mansoni calmodulin related calcium binding protein 0.0054 0.0228 0.0228
Schistosoma mansoni hypothetical protein 0.0054 0.0228 0.0228
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0036 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0314 0.0314
Giardia lamblia Cathepsin B precursor 0.015 0.0863 0.261
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0649 0.418 0.8913
Schistosoma mansoni calpain-2 (C02 family) 0.0119 0.0657 0.0657
Loa Loa (eye worm) prolyl oligopeptidase 0.051 0.3258 0.3258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0036 0.0078
Echinococcus granulosus calbindin 32 0.0055 0.0231 0.0231
Onchocerca volvulus 0.0035 0.0098 0.0098
Trypanosoma cruzi centrin, putative 0.0054 0.0228 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Brugia malayi calcium-binding protein 0.0054 0.0228 0.0228
Trichomonas vaginalis calpain, putative 0.0119 0.0657 0.1401
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.014 0.0298
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Brugia malayi Cathepsin L-like precursor 0.0447 0.2835 0.2835
Brugia malayi cathepsin B-like cysteine proteinase 0.1338 0.8759 0.8759
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2493
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0395 0.2493 0.2472
Echinococcus multilocularis cathepsin b 0.1338 0.8759 0.8759
Brugia malayi CXXC zinc finger family protein 0.003 0.0068 0.0068
Schistosoma mansoni cathepsin B (C01 family) 0.015 0.0863 0.0863
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.015 0.0863 0.1839
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0202 0.1213 0.1213
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0132 0.0132
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0027 0.0027
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0027 0.0058
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0517 0.3305 0.3287
Loa Loa (eye worm) RGS-3 protein 0.004 0.0132 0.0132
Brugia malayi prolyl oligopeptidase family protein 0.0276 0.17 0.17
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0863 0.1839
Plasmodium falciparum cysteine proteinase falcipain 3 0.0649 0.418 1
Loa Loa (eye worm) hypothetical protein 0.0929 0.6038 0.6038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0649 0.418 0.8913
Loa Loa (eye worm) EF hand family protein 0.0054 0.0228 0.0228
Echinococcus granulosus glycoprotein Antigen 5 0.0139 0.079 0.079
Leishmania major hypothetical protein, conserved 0.0045 0.0164 0.0137
Brugia malayi calpain D 0.0119 0.0657 0.0657
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.0479 0.0479
Loa Loa (eye worm) calpain D 0.0119 0.0657 0.0657
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0276 0.17 0.1677
Trypanosoma cruzi major cysteine proteinase, putative 0.015 0.0863 0.0863
Brugia malayi hypothetical protein 0.0159 0.0921 0.0921
Echinococcus granulosus cathepsin l cysteine peptidase 0.0649 0.418 0.418
Schistosoma mansoni cathepsin S (C01 family) 0.015 0.0863 0.0863
Giardia lamblia Cathepsin L-like protease 0.015 0.0863 0.261
Echinococcus multilocularis caspase 8 0.0284 0.1753 0.1753
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0139 0.079 0.079
Brugia malayi proteasome subunit beta type 2 0.0041 0.014 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0352 0.2207 0.4707
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0027 0.0065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.015 0.0863 0.0863
Loa Loa (eye worm) hypothetical protein 0.0069 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0447 0.2835 0.2835
Loa Loa (eye worm) hypothetical protein 0.0035 0.0099 0.0099
Trypanosoma brucei kinesin, putative 0.0276 0.1704 0.1681
Brugia malayi cathepsin L-like cysteine proteinase 0.015 0.0863 0.0863
Plasmodium falciparum serine repeat antigen 5 0.015 0.0863 0.2012
Giardia lamblia Cathepsin B precursor 0.015 0.0863 0.261
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0086 0.0086
Onchocerca volvulus 0.0649 0.418 0.418
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0054 0.0228 0.0228
Echinococcus multilocularis cathepsin L cysteine protease 0.0649 0.418 0.418
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2493 0.2472
Echinococcus granulosus programmed cell death protein 0.0054 0.0228 0.0228
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0631
Brugia malayi Calmodulin-like protein 0.0054 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0132
Loa Loa (eye worm) calpain family protein 1 0.0771 0.4991 0.4991
Onchocerca volvulus 0.0063 0.029 0.029
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.079 0.079
Echinococcus multilocularis expressed protein 0.0775 0.5015 0.5015
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0164 0.0164
Entamoeba histolytica prolyl oligopeptidase family protein 0.0185 0.1097 0.2624
Brugia malayi hypothetical protein 0.0091 0.0471 0.0471
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0009 0.0009
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0185 0.1097 0.2339
Trypanosoma brucei calmodulin, putative 0.0054 0.0228 0.0201
Brugia malayi Cell death protein 3 precursor 0.0506 0.3232 0.3232
Trypanosoma brucei metacaspase 0.0284 0.1753 0.1731
Schistosoma mansoni calpain-7 (C02 family) 0.0395 0.2493 0.2493
Trichomonas vaginalis calmodulin-2, putative 0.0054 0.0228 0.0486
Entamoeba histolytica cysteine protease, putative 0.0352 0.2207 0.5281
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0119 0.0657 0.1401
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0009 0.0009
Toxoplasma gondii troponin c, isotype gamma, putative 0.0054 0.0228 0.0228
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0054 0.0228 0.0201
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0066 0.0307 0.0654
Echinococcus granulosus calpain 0.0395 0.2493 0.2493
Loa Loa (eye worm) hypothetical protein 0.1338 0.8759 0.8759
Loa Loa (eye worm) hypothetical protein 0.0771 0.4991 0.4991
Brugia malayi calpain 5 0.0276 0.1704 0.1704
Trichomonas vaginalis centrin, putative 0.0054 0.0228 0.0486
Onchocerca volvulus Deterin homolog 0.0138 0.0781 0.0781
Echinococcus multilocularis caspase 2 0.0506 0.3232 0.3232
Entamoeba histolytica hypothetical protein 0.004 0.0132 0.0316
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0657 0.0657
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0059 0.0059
Trypanosoma cruzi metacaspase, putative 0.0284 0.1753 0.1753
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0009 0.0009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0099 0.0083
Trypanosoma cruzi I/6 autoantigen, putative 0.0054 0.0228 0.0228
Trypanosoma brucei oligopeptidase b 0.0623 0.4009 0.3993
Onchocerca volvulus 0.0029 0.0059 0.0059
Brugia malayi Papain family cysteine protease containing protein 0.0649 0.418 0.418
Entamoeba histolytica calpain family cysteine protease, putative 0.0119 0.0657 0.1572
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0284 0.1753 0.3739
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0009 0.0009
Giardia lamblia Cathepsin L precursor 0.015 0.0863 0.261
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0371 0.233 0.233
Onchocerca volvulus 0.0035 0.0099 0.0099
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0099 0.0034
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0009 0.0009
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0284 0.1753 0.1753
Brugia malayi Cytochrome P450 family protein 0.0033 0.0086 0.0086
Trypanosoma brucei calpain-like protein, putative 0.0395 0.2493 0.2472
Trypanosoma cruzi metacaspase, putative 0.0284 0.1753 0.1753
Loa Loa (eye worm) hypothetical protein 0.004 0.0132 0.0132
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0138 0.0781 0.0781
Brugia malayi hypothetical protein 0.0063 0.029 0.029
Brugia malayi PXA domain containing protein 0.004 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.029
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0173 0.0415
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.015 0.0863 0.0863
Trypanosoma cruzi centrin-3 0.0054 0.0228 0.0228
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0638 0.4105 0.4105
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0009 0.0009
Onchocerca volvulus 0.0029 0.0059 0.0059
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.015 0.0863 0.2012
Plasmodium vivax proteasome subunit beta type-2, putative 0.0041 0.014 0.0271
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0132 0.0132
Plasmodium vivax hypothetical protein, conserved 0.0284 0.1753 0.4157
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0132 0.0132
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0517 0.3305 0.3305
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0228 0.0228
Echinococcus multilocularis calcium uptake protein 1 0.0055 0.0231 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0132 0.0282
Brugia malayi Peroxidasin 0.0063 0.029 0.029
Leishmania major proteasome beta 5 subunit, putative 0.0085 0.0433 0.0407
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0099 0.0212
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1338 0.8759 0.8759
Mycobacterium tuberculosis Conserved protein 0.0035 0.0099 0.0083
Leishmania major hypothetical protein, conserved 0.0054 0.0228 0.0201
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0657 0.0657
Trypanosoma brucei centrin, putative 0.0054 0.0228 0.0201
Onchocerca volvulus 0.0029 0.0059 0.0059
Schistosoma mansoni cercarial elastase (S01 family) 0.0139 0.079 0.079
Echinococcus granulosus cpg binding protein 0.0032 0.0079 0.0079
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0027 0.0027
Trichomonas vaginalis calmodulin, putative 0.0054 0.0228 0.0486
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0138 0.0781 0.0781

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 15 uM Inhibition of amyloid beta protein production in transfected H4 (neuroglioma) cells expressing APF constructs. ChEMBL. 12643944
IC50 (functional) = 15 uM Inhibition of amyloid beta protein production in transfected H4 (neuroglioma) cells expressing APF constructs. ChEMBL. 12643944

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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