Detailed information for compound 230805

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 617.778 | Formula: C35H47N5O5
  • H donors: 4 H acceptors: 4 LogP: 4.02 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 2
  • SMILES: NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)C([C@H](c1c[nH]c2c1cccc2)C)NC(=O)C1CCCN(C1)C(=O)c1ccccc1
  • InChi: 1S/C35H47N5O5/c1-23(27-21-37-28-17-9-8-16-26(27)28)30(32(42)38-29(18-10-11-19-36)34(44)45-35(2,3)4)39-31(41)25-15-12-20-40(22-25)33(43)24-13-6-5-7-14-24/h5-9,13-14,16-17,21,23,25,29-30,37H,10-12,15,18-20,22,36H2,1-4H3,(H,38,42)(H,39,41)/t23-,25?,29-,30?/m0/s1
  • InChiKey: WUJRAAAJGYHYTA-MANYEXHGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens somatostatin receptor 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus pyroglutamylated rfamide peptide receptor somatostatin receptor 2 369 aa 411 aa 18.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0061 0.0209 0.0209
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0045 0.0133 0.0133
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0163 0.0715 0.2357
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0163 0.0715 0.2373
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0105 0.0105
Giardia lamblia Cathepsin L precursor 0.0163 0.0715 0.1978
Schistosoma mansoni cathepsin F (C01 family) 0.0626 0.301 0.301
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0267 0.1231 0.1689
Entamoeba histolytica grainin 2 0.0083 0.0319 0.1039
Toxoplasma gondii centrin 0.0083 0.0319 0.0437
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0029 0.0094
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0163 0.0715 0.2373
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0012 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Echinococcus multilocularis neurocalcin 0.0083 0.0319 0.0318
Giardia lamblia Cathepsin L precursor 0.0163 0.0715 0.1978
Trypanosoma cruzi cysteine peptidase, putative 0.0188 0.0839 0.0838
Trypanosoma brucei Calpain-like protein 2 0.0157 0.0687 0.0942
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0715 0.1982
Loa Loa (eye worm) hypothetical protein 0.0083 0.0319 0.0319
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0039 0.0103 0.0102
Toxoplasma gondii histone deacetylase HDAC3 0.0065 0.0233 0.0318
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0012 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Loa Loa (eye worm) hypothetical protein 0.0163 0.0715 0.0715
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0436 0.1202
Brugia malayi Cathepsin L-like cysteine proteinase 0.0438 0.208 0.2079
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0042 0.0116 0.0382
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0595 0.0594
Brugia malayi cathepsin L precursor 0.0163 0.0715 0.0714
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0436 0.2068 0.2068
Leishmania major cathepsin L-like protease 0.0724 0.3494 0.4796
Entamoeba histolytica cysteine proteinase, putative 0.0351 0.1646 0.5456
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.028
Echinococcus multilocularis hypothetical protein 0.0523 0.2499 0.2498
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0012 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0012 0.0011
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0029 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0005
Schistosoma mansoni calmodulin 0.0083 0.0319 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.2037 1 1
Plasmodium vivax SET domain protein, putative 0.0064 0.0226 0.0749
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0105 0.0105
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.002 0.0007 0.0006
Plasmodium vivax vivapain-1 0.0351 0.1646 0.5465
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Brugia malayi Pre-SET motif family protein 0.0436 0.2068 0.2068
Leishmania major hypothetical protein, conserved 0.0024 0.0029 0.0039
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1386 0.6776 0.6776
Trypanosoma brucei Component of motile flagella 41 0.0083 0.0319 0.0437
Echinococcus multilocularis glycoprotein Antigen 5 0.0061 0.0209 0.0209
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Echinococcus granulosus glycoprotein Antigen 5 0.0061 0.0209 0.0209
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0105 0.0105
Brugia malayi Thioredoxin family protein 0.0035 0.0082 0.0081
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0163 0.0715 0.2373
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0608 0.2921 1
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0105 0.0105
Echinococcus granulosus inhibitor of apoptosis protein 0.0039 0.0103 0.0102
Toxoplasma gondii kringle domain-containing protein 0.004 0.0109 0.0148
Entamoeba histolytica cysteine protease, putative 0.0163 0.0715 0.2357
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0163 0.0715 0.0715
Onchocerca volvulus 0.0051 0.0161 0.0221
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Toxoplasma gondii hypothetical protein 0.0157 0.0687 0.0942
Echinococcus multilocularis calumenin 0.0084 0.0326 0.0325
Echinococcus granulosus Tolloid protein 1 0.0045 0.0133 0.0133
Leishmania major programmed cell death 6 protein-like protein 0.0083 0.0319 0.0437
Onchocerca volvulus 0.0039 0.0103 0.014
Onchocerca volvulus 0.002 0.0007 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0161 0.0161
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0077 0.0076
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.002 0.0007 0.0006
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0083 0.0319 0.0318
Schistosoma mansoni neuronal calcium sensor 0.0083 0.0319 0.0318
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0029 0.0028
Echinococcus granulosus cathepsin l cysteine peptidase 0.0626 0.301 0.301
Onchocerca volvulus Prolyl endopeptidase homolog 0.1489 0.7284 1
Echinococcus granulosus EF hand domain containing family member A2 0.0084 0.0326 0.0325
Echinococcus multilocularis tumor protein p63 0.0354 0.1664 0.1664
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0163 0.0715 0.2373
Onchocerca volvulus 0.0021 0.0012 0.0016
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.0687 0.0686
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0163 0.0715 0.0714
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0715 0.0714
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0595 0.0594
Echinococcus granulosus cathepsin b 0.2037 1 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0157 0.0687 0.0686
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0012 0.0011
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0071 0.0071
Onchocerca volvulus 0.0061 0.0209 0.0286
Echinococcus multilocularis geminin 0.0169 0.0747 0.0746
Entamoeba histolytica cysteine proteinase, putative 0.0351 0.1646 0.5456
Entamoeba histolytica prolyl oligopeptidase family protein 0.018 0.0801 0.2643
Loa Loa (eye worm) hypothetical protein 0.0163 0.0715 0.0715
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0491 0.2343 0.2342
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.1646 0.4581
Trichomonas vaginalis conserved hypothetical protein 0.0157 0.0687 0.1904
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Toxoplasma gondii cathepsin CPC1 0.0163 0.0715 0.098
Brugia malayi Cathepsin L-like precursor 0.0438 0.208 0.2079
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0105 0.0105
Echinococcus multilocularis calmodulin 0.0083 0.0319 0.0318
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0042 0.0116 0.0115
Onchocerca volvulus Deterin homolog 0.0039 0.0103 0.014
Brugia malayi hypothetical protein 0.0061 0.0209 0.0209
Toxoplasma gondii hypothetical protein 0.018 0.0801 0.1098
Schistosoma mansoni cpg binding protein 0.0086 0.0335 0.0334
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0105 0.0105
Schistosoma mansoni centrin 0.0083 0.0319 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0715 0.1982
Entamoeba histolytica calpain large subunit domain III containing protein 0.0366 0.172 0.5704
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0012 0.0011
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Giardia lamblia Cathepsin L-like protease 0.0163 0.0715 0.1978
Trichomonas vaginalis peptide N-glycanase, putative 0.0035 0.0082 0.0215
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0157 0.0687 0.0686
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0626 0.301 1
Trichomonas vaginalis myosin light chain 1, putative 0.0083 0.0319 0.0877
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2037 1 1
Brugia malayi Calmodulin-like protein 0.0083 0.0319 0.0318
Echinococcus multilocularis cysteine protease 0.0626 0.301 0.301
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0523 0.2499 0.2498
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.0209
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0012 0.0011
Loa Loa (eye worm) calpain D 0.0157 0.0687 0.0687
Trypanosoma cruzi cysteine peptidase, putative 0.0724 0.3494 0.3494
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0052 0.0051
Brugia malayi Pre-SET motif family protein 0.0064 0.0226 0.0225
Plasmodium falciparum serine repeat antigen 9 0.0163 0.0715 0.2373
Schistosoma mansoni hypothetical protein 0.0169 0.0747 0.0746
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Echinococcus granulosus tissue type plasminogen activator 0.004 0.0109 0.0108
Echinococcus granulosus cpg binding protein 0.0091 0.0359 0.0359
Giardia lamblia Cysteine protease 0.0163 0.0715 0.1978
Plasmodium falciparum histone deacetylase 1 0.0065 0.0233 0.077
Plasmodium falciparum proteasome subunit beta type-5 0.0087 0.0339 0.1124
Plasmodium vivax calpain, putative 0.0523 0.2499 0.83
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0326 0.1081
Plasmodium falciparum serine repeat antigen 8 0.0163 0.0715 0.2373
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Echinococcus multilocularis caspase 2 0.003 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Trypanosoma cruzi cysteine proteinase, putative 0.0351 0.1646 0.1645
Schistosoma mansoni regulator of G protein signaling 0.004 0.0105 0.0105
Entamoeba histolytica prolyl oligopeptidase family protein 0.018 0.0801 0.2643
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0083 0.0319 0.1058
Schistosoma mansoni regulator of G protein signaling 0.004 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.028
Onchocerca volvulus 0.0061 0.0209 0.0286
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0436 0.0435
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0012 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0012 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0801 0.2222
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0007
Schistosoma mansoni cathepsin F (C01 family) 0.0438 0.208 0.2079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0136 0.0431
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.084 0.0839
Entamoeba histolytica cysteine protease, putative 0.0626 0.301 1
Plasmodium vivax histone deacetylase 1, putative 0.0065 0.0233 0.077
Echinococcus multilocularis histone deacetylase 1 0.0065 0.0233 0.0232
Trypanosoma brucei Aph-1 protein, putative 0.0096 0.0385 0.0527
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0351 0.1646 0.1645
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Echinococcus multilocularis dnaJ subfamily B 0.0822 0.3978 0.3978
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Leishmania major i/6 autoantigen-like protein 0.0083 0.0319 0.0437
Trichomonas vaginalis calcium binding protein, putative 0.0083 0.0319 0.0877
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0267 0.1231 0.1689
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Onchocerca volvulus 0.004 0.0109 0.0148
Leishmania major histone deacetylase, putative 0.0065 0.0233 0.0318
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0608 0.2921 0.401
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0095 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0715 0.1982
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0068 0.0243 0.0665
Brugia malayi Papain family cysteine protease containing protein 0.0351 0.1646 0.1645
Trypanosoma cruzi cysteine proteinase, putative 0.0351 0.1646 0.1645
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0163 0.0715 0.2373
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0715 0.1982
Toxoplasma gondii cathepsin CPC2 0.0163 0.0715 0.098
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Loa Loa (eye worm) hypothetical protein 0.0438 0.208 0.208
Loa Loa (eye worm) hypothetical protein 0.0163 0.0715 0.0715
Trypanosoma brucei Calpain-like protein 1.2 0.0157 0.0687 0.0942
Plasmodium falciparum serine repeat antigen 5 0.0163 0.0715 0.2373
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0105 0.0105
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0436 0.1427
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0251 0.115 0.115
Brugia malayi Cathepsin L-like precursor 0.0626 0.301 0.301
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0095 0.5
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0012 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Leishmania major cathepsin L-like protease 0.0724 0.3494 0.4796
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0105
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0105 0.0105
Brugia malayi Serine protease Z688.6 precursor 0.002 0.0007 0.0006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0105 0.0105
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0012 0.0011
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0715 0.1978
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Trichomonas vaginalis histone deacetylase, putative 0.0065 0.0233 0.0636
Echinococcus granulosus calumenin 0.0084 0.0326 0.0325
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0157 0.0687 0.0942
Entamoeba histolytica cysteine protease, putative 0.0163 0.0715 0.2357
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0095 0.0247
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0061 0.0209 0.0209
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0087 0.0339 0.0339
Trypanosoma cruzi cruzipain precursor, putative 0.0188 0.0839 0.0838
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0026 0.0025
Echinococcus granulosus enteropeptidase 0.0061 0.0209 0.0209
Trypanosoma brucei calpain-like protein, putative 0.0523 0.2499 0.343
Echinococcus multilocularis apoptotic protease activating factor 1 0.003 0.0056 0.0055
Echinococcus granulosus axis inhibition protein axin 0.004 0.0105 0.0105
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0715 0.0714
Plasmodium falciparum serine repeat antigen 4 0.0163 0.0715 0.2373
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0087 0.0339 0.1106
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0223 0.0222
Plasmodium falciparum calpain 0.0157 0.0687 0.228
Echinococcus granulosus prolyl endopeptidase 0.1489 0.7284 0.7284
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0012 0.0011
Plasmodium vivax unspecified product 0.0351 0.1646 0.5465
Onchocerca volvulus 0.0626 0.301 0.4132
Loa Loa (eye worm) prolyl oligopeptidase 0.018 0.0801 0.0801
Toxoplasma gondii histone deacetylase HDAC5 0.0019 0.0002 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0029 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.1646 0.2258
Echinococcus multilocularis peroxidasin 0.0063 0.0223 0.0222
Brugia malayi nuclear hormone receptor 0.0021 0.0012 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0715 0.1982
Toxoplasma gondii EFHC1, putative 0.0083 0.0319 0.0437
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.002 0.0007 0.0005
Echinococcus multilocularis cathepsin L 0.0163 0.0715 0.0714
Brugia malayi Trypsin family protein 0.0061 0.0209 0.0209
Leishmania major cathepsin L-like protease 0.0626 0.301 0.4132
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Echinococcus granulosus cathepsin l1 0.0626 0.301 0.301
Onchocerca volvulus 0.0052 0.0165 0.0226
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.0825 0.0824
Schistosoma mansoni hypothetical protein 0.004 0.0109 0.0108
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0163 0.0715 0.2373
Trypanosoma cruzi major cysteine proteinase, putative 0.026 0.1199 0.1198
Leishmania major calpain family cysteine protease-like protein 0.0157 0.0687 0.0942
Brugia malayi hypothetical protein 0.0024 0.0029 0.0028
Trypanosoma brucei prolyl oligopeptidase, putative 0.0608 0.2921 0.401
Giardia lamblia Hypothetical protein 0.0035 0.0082 0.021
Brugia malayi prolyl oligopeptidase family protein 0.018 0.0801 0.08
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0626 0.301 0.301
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0083 0.0319 0.0318
Brugia malayi calpain family protein 1 0.1386 0.6776 0.6776
Brugia malayi hypothetical protein 0.003 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0103
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0095 0.0095
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0105 0.028
Entamoeba histolytica calmodulin, putative 0.0083 0.0319 0.1039
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0045 0.0133 0.0133
Schistosoma mansoni ef hand domain family member A2 0.0083 0.0319 0.0318
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1469 0.7187 0.7186
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0068 0.0243 0.0333
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0351 0.1646 0.1645
Leishmania major calmodulin-like protein 0.0083 0.0319 0.0437
Entamoeba histolytica calmodulin, putative 0.0083 0.0319 0.1039
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0029
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0436 0.0435
Trypanosoma cruzi prolyl endopeptidase 0.1489 0.7284 0.7284
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Mycobacterium ulcerans putative transglutaminase-like protein 0.0035 0.0082 0.0039
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0163 0.0715 0.0715
Echinococcus multilocularis calmodulin 0.0083 0.0319 0.0318
Echinococcus multilocularis calpain 5 0.0523 0.2499 0.2498
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0105 0.0105
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0095 0.013
Trypanosoma cruzi cruzipain precursor, putative 0.0724 0.3494 0.3494
Onchocerca volvulus Cathepsin L homolog 0.0163 0.0715 0.098
Trichomonas vaginalis set domain proteins, putative 0.0496 0.2366 0.6591
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0163 0.0715 0.1982
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.002 0.0007 0.0006
Plasmodium vivax proteasome subunit beta type-1, putative 0.0068 0.0243 0.0805
Brugia malayi hypothetical protein 0.0159 0.0694 0.0693
Leishmania major protein kinase, putative 0.0083 0.0319 0.0437
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.2498
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0012 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Echinococcus granulosus caspase 2 0.003 0.0056 0.0055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0061 0.0209 0.0209
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0351 0.1646 0.1645
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0012 0.0011
Giardia lamblia Cathepsin L precursor 0.0163 0.0715 0.1978
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0715 0.0714
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0165 0.0164
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0177 0.0177
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0715 0.0714
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0068 0.0243 0.0242
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Leishmania major calmodulin-like protein 0.0083 0.0319 0.0437
Giardia lamblia Cathepsin L precursor 0.0163 0.0715 0.1978
Trypanosoma cruzi cysteine peptidase, putative 0.0351 0.1646 0.1645
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0715 0.1982
Trypanosoma cruzi cysteine peptidase, putative 0.0724 0.3494 0.3494
Echinococcus multilocularis Mastin 0.0061 0.0209 0.0209
Schistosoma mansoni peroxidasin 0.0063 0.0223 0.0222
Trypanosoma cruzi Aph-1 protein, putative 0.0096 0.0385 0.0384
Echinococcus multilocularis calpain 0.0523 0.2499 0.2498
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0012 0.0011
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0188 0.084 0.0839
Onchocerca volvulus 0.0626 0.301 0.4132
Echinococcus multilocularis EF hand domain containing family member A2 0.0083 0.0319 0.0318
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0743 0.3587 0.3586
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0223 0.0222
Toxoplasma gondii exonuclease III APE 0.0038 0.0095 0.013
Giardia lamblia Glycogen phosphorylase 0.0106 0.0436 0.1197
Trichomonas vaginalis calcium binding protein, putative 0.0083 0.0319 0.0877
Trypanosoma cruzi caltractin, putative 0.0083 0.0319 0.0318
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0061 0.0209 0.0209
Schistosoma mansoni axis inhibition protein axin 0.004 0.0105 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0226 0.0225
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0029 0.0094
Onchocerca volvulus Cathepsin L homolog 0.0626 0.301 0.4132
Loa Loa (eye worm) TK/ROR protein kinase 0.004 0.0109 0.0109
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0595 0.0594
Schistosoma mansoni calpain-7 (C02 family) 0.0523 0.2499 0.2498
Loa Loa (eye worm) hypothetical protein 0.0064 0.0226 0.0226
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Brugia malayi prolyl oligopeptidase family protein 0.1489 0.7284 0.7284
Loa Loa (eye worm) histone deacetylase 1 0.0065 0.0233 0.0233
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0012 0.0016
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0012 0.0011
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0163 0.0715 0.2373
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0095 0.0095
Trypanosoma cruzi hypothetical protein, conserved 0.018 0.0801 0.08
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0056
Trichomonas vaginalis histone deacetylase, putative 0.0065 0.0233 0.0636
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0095 0.013
Brugia malayi Kringle domain containing protein 0.004 0.0109 0.0108
Brugia malayi calpain 5 0.0157 0.0687 0.0686
Schistosoma mansoni cathepsin F (C01 family) 0.0626 0.301 0.301
Loa Loa (eye worm) hypothetical protein 0.0163 0.0715 0.0715
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Trypanosoma brucei hypothetical protein, conserved 0.0083 0.0319 0.0437
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0794 0.3844 0.3843
Brugia malayi calpain 5 0.0366 0.172 0.1719
Onchocerca volvulus 0.0084 0.0326 0.0447
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0012 0.0016
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2037 1 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0188 0.0839 0.0838
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0012 0.0011
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0061 0.0209 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0438 0.208 0.5793
Echinococcus granulosus neuronal calcium sensor 0.0083 0.0319 0.0318
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0436 0.1427
Schistosoma mansoni neuronal calcium sensor 0.0083 0.0319 0.0318
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.0687 0.0686
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Schistosoma mansoni hypothetical protein 0.0822 0.3978 0.3978
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0715 0.1982
Trypanosoma brucei calpain, putative 0.0157 0.0687 0.0942
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1469 0.7187 0.7186
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0105 0.0105
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Brugia malayi hypothetical protein 0.0063 0.0223 0.0222
Giardia lamblia Alanyl dipeptidyl peptidase 0.018 0.0801 0.2217
Schistosoma mansoni survival motor neuron protein 0.0051 0.0161 0.0161
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0436 0.1202
Schistosoma mansoni gamma-secretase subunit aph-1 0.0247 0.1132 0.1131
Plasmodium vivax proteasome subunit beta type-5, putative 0.0087 0.0339 0.1124
Loa Loa (eye worm) hypothetical protein 0.0163 0.0715 0.0715
Loa Loa (eye worm) hypothetical protein 0.0188 0.0839 0.0839
Brugia malayi MH2 domain containing protein 0.0115 0.048 0.0479
Onchocerca volvulus 0.0035 0.0082 0.0112
Loa Loa (eye worm) calpain family protein 1 0.1021 0.4964 0.4964
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Schistosoma mansoni peroxidasin 0.0063 0.0223 0.0222
Schistosoma mansoni hypothetical protein 0.0061 0.0209 0.0209
Giardia lamblia Cathepsin B precursor 0.0743 0.3587 1
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0267 0.1231 0.1689
Echinococcus multilocularis enteropeptidase 0.0061 0.0209 0.0209
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0083 0.0319 0.0318
Brugia malayi prolyl oligopeptidase family protein 0.0267 0.1231 0.123
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0083 0.0319 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0743 0.3587 1
Trypanosoma cruzi centrin, putative 0.0083 0.0319 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0438 0.208 0.5793
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0188 0.0839 0.0838
Schistosoma mansoni calmodulin 0.0083 0.0319 0.0318
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0095 0.0314
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0095 0.5
Echinococcus multilocularis EF hand domain containing family member A2 0.0084 0.0326 0.0325
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Giardia lamblia Histone deacetylase 0.0065 0.0233 0.0631
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0068 0.0243 0.0333
Leishmania major centrin, putative,caltractin, putative 0.0083 0.0319 0.0437
Entamoeba histolytica hypothetical protein, conserved 0.0084 0.0326 0.1063
Brugia malayi cathepsin F-like cysteine proteinase 0.0163 0.0715 0.0714
Leishmania major calmodulin, putative 0.0083 0.0319 0.0437
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0351 0.1646 0.1645
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0319 0.0319
Schistosoma mansoni cpg binding protein 0.0091 0.0359 0.0359
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0523 0.2499 0.2498
Trypanosoma cruzi cysteine peptidase, putative 0.0626 0.301 0.301
Toxoplasma gondii EF hand domain-containing protein 0.0083 0.0319 0.0437
Leishmania major proteasome beta 5 subunit, putative 0.0087 0.0339 0.0464
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0087 0.0339 0.0928
Brugia malayi Cathepsin L-like precursor 0.0438 0.208 0.2079
Schistosoma mansoni coup transcription factor 0.0021 0.0012 0.0011
Trichomonas vaginalis calpain, putative 0.0157 0.0687 0.1904
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0163 0.0715 0.2373
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.084 0.2697
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0223 0.0223
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0105 0.0105
Echinococcus granulosus peroxidasin 0.0063 0.0223 0.0222
Giardia lamblia Hypothetical protein 0.0084 0.0326 0.0892
Schistosoma mansoni hypothetical protein 0.0083 0.0319 0.0318
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0095 0.0095
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0371 0.1744 0.1743
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0065 0.0233 0.0636
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0083 0.0319 0.0318
Leishmania major phospholipase c-like protein 0.0083 0.0319 0.0437
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.0687 0.1904
Echinococcus multilocularis proteasome (prosome, macropain) 0.0087 0.0339 0.0338
Plasmodium falciparum peptidase, putative 0.018 0.0801 0.2658
Loa Loa (eye worm) histone deacetylase 3 0.0065 0.0233 0.0233
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0163 0.0715 0.0715
Echinococcus granulosus cathepsin l1 0.0438 0.208 0.2079
Brugia malayi Cytochrome P450 family protein 0.0033 0.0071 0.007
Onchocerca volvulus 0.0063 0.0223 0.0305
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Plasmodium falciparum centrin-1 0.0083 0.0319 0.1058
Onchocerca volvulus Chorion peroxidase homolog 0.0063 0.0223 0.0305
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.002 0.0007 0.0005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0012 0.0011
Schistosoma mansoni calpain-2 (C02 family) 0.0157 0.0687 0.0686
Trypanosoma cruzi Aph-1 protein, putative 0.0096 0.0385 0.0384
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0042 0.0116 0.0158
Trypanosoma brucei Calpain-like protein CALP1.3 0.0157 0.0687 0.0942
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0105
Giardia lamblia Transglutaminase/protease, putative 0.0035 0.0082 0.021
Schistosoma mansoni cathepsin s 0.0188 0.0839 0.0838
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0103
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0536 0.2564 0.2563
Leishmania major hypothetical protein, conserved 0.004 0.0109 0.0148
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0095 0.0253
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0026 0.0025
Schistosoma mansoni histone deacetylase 0.0065 0.0233 0.0232
Loa Loa (eye worm) hypothetical protein 0.1489 0.7284 0.7284
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0083 0.0319 0.0877
Schistosoma mansoni hypothetical protein 0.003 0.0056 0.0055
Echinococcus granulosus axis inhibition protein axin 0.004 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0163 0.0715 0.1982
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0061 0.0209 0.0209
Onchocerca volvulus Cathepsin L homolog 0.0626 0.301 0.4132
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0436 0.0435
Echinococcus granulosus Transglutaminase 0.0035 0.0082 0.0081
Brugia malayi histone deacetylase 1 (HD1) 0.0065 0.0233 0.0232
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0105 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0226 0.0225
Echinococcus multilocularis histone deacetylase 3 0.0065 0.0233 0.0232
Brugia malayi prolyl oligopeptidase family protein 0.018 0.0801 0.08
Plasmodium falciparum cysteine proteinase falcipain 1 0.0351 0.1646 0.5465
Trypanosoma brucei hypothetical protein 0.0157 0.0687 0.0942
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0012 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0012 0.0011
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0012 0.0011
Brugia malayi Cathepsin L-like precursor 0.0188 0.0839 0.0838
Echinococcus granulosus tumor protein p63 0.0354 0.1664 0.1664
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0188 0.084 0.1152
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0188 0.084 0.1201
Schistosoma mansoni caspase-7 (C14 family) 0.003 0.0056 0.0055
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Mycobacterium tuberculosis Probable peptidase 0.0608 0.2921 0.45
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Leishmania major cathepsin L-like protease 0.0626 0.301 0.4132
Leishmania major hypothetical protein, conserved 0.0083 0.0319 0.0437
Echinococcus multilocularis calpain A 0.1471 0.7194 0.7194
Onchocerca volvulus 0.0863 0.4185 0.5745
Entamoeba histolytica prolyl oligopeptidase family protein 0.018 0.0801 0.2643
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0042 0.0116 0.0115
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0087 0.0339 0.0464
Brugia malayi calpain 7 0.0523 0.2499 0.2498
Schistosoma mansoni ap endonuclease 0.0038 0.0095 0.0095
Echinococcus multilocularis calcium uptake protein 1 0.0084 0.0326 0.0325
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Entamoeba histolytica cysteine proteinase 1, putative 0.0351 0.1646 0.5456
Trypanosoma cruzi calmodulin, putative 0.0083 0.0319 0.0318
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.0209
Onchocerca volvulus 0.0063 0.0223 0.0305
Trypanosoma cruzi histone deacetylase 1, putative 0.0065 0.0233 0.0232
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0371 0.1744 0.1743
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0163 0.0715 0.0714
Onchocerca volvulus 0.0063 0.0223 0.0305
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0523 0.2499 0.2498
Brugia malayi gamma-secretase subunit aph-1 0.0247 0.1132 0.1131
Leishmania major proteasome beta 2 subunit, putative 0.0042 0.0116 0.0158
Loa Loa (eye worm) hypothetical protein 0.0438 0.208 0.208
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0863 0.4185 0.4185
Brugia malayi Blistered cuticle protein 3 0.0063 0.0223 0.0222
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.0687 0.1904
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0105 0.0105
Echinococcus multilocularis calpain family protein 1, d 0.1021 0.4964 0.4964
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0163 0.0715 0.2373
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0068 0.0243 0.0242
Trypanosoma brucei antigen, putative 0.0523 0.2499 0.343
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0012 0.0011
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.018 0.0801 0.08
Giardia lamblia Cathepsin B precursor 0.0163 0.0715 0.1978
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0012 0.0011
Onchocerca volvulus 0.0163 0.0715 0.098
Loa Loa (eye worm) hypothetical protein 0.0626 0.301 0.301
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0163 0.0715 0.2357
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0491 0.2343 0.2342
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0155 0.0154
Loa Loa (eye worm) programmed cell death protein 6 0.0084 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0715 0.1982
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Plasmodium vivax hypothetical protein, conserved 0.018 0.0801 0.2658
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0595 0.0594
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0105
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0267 0.1231 0.123
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0715 0.1982
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Loa Loa (eye worm) hypothetical protein 0.1229 0.5997 0.5997
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Brugia malayi PXA domain containing protein 0.004 0.0105 0.0105
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0595 0.0594
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0105 0.0105
Leishmania major calmodulin, putative 0.0083 0.0319 0.0437
Trichomonas vaginalis calcium binding protein, putative 0.0083 0.0319 0.0877
Trypanosoma cruzi centrin, putative 0.0083 0.0319 0.0318
Echinococcus granulosus acylamino acid releasing enzyme 0.018 0.0801 0.08
Entamoeba histolytica cysteine protease, putative 0.0163 0.0715 0.2357
Brugia malayi Cathepsin L-like precursor 0.0626 0.301 0.301
Schistosoma mansoni cathepsin B (C01 family) 0.0163 0.0715 0.0714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0715 0.1982
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Plasmodium falciparum serine repeat antigen 1 0.0163 0.0715 0.2373
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0071 0.0097
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0608 0.2921 0.45
Mycobacterium ulcerans hypothetical protein 0.0035 0.0082 0.0039
Entamoeba histolytica dipeptidyl-peptidase, putative 0.018 0.0801 0.2643
Onchocerca volvulus 0.0496 0.2367 0.3249
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1469 0.7187 0.7186
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0012 0.0012
Echinococcus granulosus transmembrane protease serine 3 0.0061 0.0209 0.0209
Trypanosoma brucei calmodulin, putative 0.0083 0.0319 0.0437
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.0209
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0083 0.0319 0.0318
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0105 0.0105
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0065 0.0233 0.0636
Schistosoma mansoni calpain C (C02 family) 0.0523 0.2499 0.2498
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0491 0.2343 0.3215
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1489 0.7284 0.7284
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Onchocerca volvulus 0.0626 0.301 0.4132
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0523 0.2499 0.2498
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0105 0.0105
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0136 0.0135
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0229 0.0228
Toxoplasma gondii centrin, putative 0.0083 0.0319 0.0437
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Plasmodium vivax unspecified product 0.0188 0.0839 0.2785
Toxoplasma gondii troponin c, isotype gamma, putative 0.0083 0.0319 0.0437
Brugia malayi EF hand family protein 0.0084 0.0326 0.0325
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0226 0.0225
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.0687 0.1904
Brugia malayi Serine protease Z688.6 precursor 0.002 0.0007 0.0006
Trypanosoma brucei Calpain-like protein 1.1 0.0157 0.0687 0.0942
Brugia malayi Cathepsin L-like precursor 0.0626 0.301 0.301
Loa Loa (eye worm) hypothetical protein 0.1386 0.6776 0.6776
Loa Loa (eye worm) hypothetical protein 0.018 0.0801 0.0801
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0155 0.0155
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0715 0.1978
Brugia malayi carbohydrate phosphorylase 0.0106 0.0436 0.0435
Mycobacterium ulcerans hypothetical protein 0.0035 0.0082 0.0039
Leishmania major cathepsin L-like protease 0.0626 0.301 0.4132
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0223 0.0223
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0026 0.0025
Onchocerca volvulus 0.003 0.0056 0.0076
Onchocerca volvulus Peroxidase homolog 0.0063 0.0223 0.0305
Giardia lamblia Cathepsin B precursor 0.0743 0.3587 1
Schistosoma mansoni microtubule-associated protein tau 0.1417 0.6926 0.6926
Onchocerca volvulus Peroxidasin homolog 0.0063 0.0223 0.0305
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0163 0.0715 0.1978
Echinococcus multilocularis cathepsin b 0.2037 1 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0608 0.2921 0.401
Trypanosoma brucei cysteine peptidase, putative 0.0157 0.0687 0.0942
Schistosoma mansoni reticulocalbin 0.0083 0.0319 0.0318
Schistosoma mansoni memapsin-2 (A01 family) 0.0452 0.2147 0.2146
Brugia malayi Serine carboxypeptidase S28 family protein 0.002 0.0007 0.0006
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0626 0.301 0.8391
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0084 0.0326 0.0325
Loa Loa (eye worm) AStacin protease 0.0028 0.0049 0.0049
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0626 0.301 0.301
Trichomonas vaginalis calcineurin B subunit, putative 0.0083 0.0319 0.0877
Giardia lamblia Cathepsin L precursor 0.0163 0.0715 0.1978
Echinococcus granulosus neurocalcin 0.0083 0.0319 0.0318
Onchocerca volvulus 0.0626 0.301 0.4132
Brugia malayi CXXC zinc finger family protein 0.0086 0.0335 0.0334
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0083 0.0319 0.0318
Loa Loa (eye worm) calpain family protein 1 0.1386 0.6776 0.6776
Giardia lamblia Cathepsin B precursor 0.0743 0.3587 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0105 0.0105
Toxoplasma gondii proteasome subunit beta type, putative 0.0087 0.0339 0.0464
Loa Loa (eye worm) ctsf protein 0.0626 0.301 0.301
Trypanosoma cruzi calmodulin, putative 0.0083 0.0319 0.0318
Schistosoma mansoni neuronal calcium sensor 0.0083 0.0319 0.0318
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0105 0.0105
Giardia lamblia Proteasome subunit beta type 2 0.0042 0.0116 0.0304
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0523 0.2499 0.343
Loa Loa (eye worm) glycogen phosphorylase 0.0106 0.0436 0.0436
Leishmania major cytochrome p450-like protein 0.0033 0.0071 0.0097
Leishmania major hypothetical protein, conserved 0.0084 0.0326 0.0447
Schistosoma mansoni reticulocalbin 0.0084 0.0326 0.0325
Trypanosoma brucei caltractin, putative 0.0083 0.0319 0.0437
Trypanosoma cruzi centrin-3 0.0083 0.0319 0.0318
Giardia lamblia Cathepsin B precursor 0.0163 0.0715 0.1978
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0105 0.0105
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0136 0.0086
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Brugia malayi cathepsin L-like precursor 0.0438 0.208 0.2079
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1489 0.7284 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Onchocerca volvulus 0.0064 0.0226 0.0309
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0077
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0068 0.0243 0.0242
Loa Loa (eye worm) hypothetical protein 0.0052 0.0165 0.0165
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Loa Loa (eye worm) histone deacetylase 11 0.0019 0.0001 0.0001
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0087 0.0339 0.0338
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0715 0.1982
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Brugia malayi cathepsin Z-like cysteine proteinase 0.0163 0.0715 0.0714
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0105
Trypanosoma cruzi oligopeptidase b 0.0608 0.2921 0.2921
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0012 0.0012
Schistosoma mansoni calmodulin related calcium binding protein 0.0083 0.0319 0.0318
Toxoplasma gondii cathepsin B 0.0743 0.3587 0.4923
Giardia lamblia Alanyl dipeptidyl peptidase 0.018 0.0801 0.2217
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1309 0.6392 1
Onchocerca volvulus 0.0061 0.0209 0.0286
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Trypanosoma brucei prolyl endopeptidase 0.1489 0.7284 1
Echinococcus multilocularis acylamino acid releasing enzyme 0.018 0.0801 0.08
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.002 0.0007 0.0006
Schistosoma mansoni hypothetical protein 0.0169 0.0747 0.0746
Loa Loa (eye worm) calpain 0.0523 0.2499 0.2499
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0039 0.0103 0.0102
Loa Loa (eye worm) RGS-3 protein 0.004 0.0105 0.0105
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0012 0.0016
Trichomonas vaginalis hypothetical protein 0.0157 0.0687 0.1904
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Echinococcus multilocularis microtubule associated protein 2 0.1417 0.6926 0.6926
Plasmodium vivax unspecified product 0.0163 0.0715 0.2373
Echinococcus multilocularis cathepsin b 0.2037 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0095 0.0095
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0042 0.0116 0.0362
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0061 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0012 0.0011
Trypanosoma brucei calmodulin, putative 0.0084 0.0326 0.0447
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.2498
Plasmodium vivax proteasome subunit beta type-2, putative 0.0042 0.0116 0.0382
Trypanosoma cruzi calmodulin, putative 0.0083 0.0319 0.0318
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0012 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Onchocerca volvulus 0.0438 0.208 0.2854
Echinococcus granulosus Mastin 0.0061 0.0209 0.0209
Toxoplasma gondii preprocathepsin c precursor, putative 0.0163 0.0715 0.098
Brugia malayi calcium-binding protein 0.0083 0.0319 0.0318
Toxoplasma gondii aldehyde dehydrogenase 0.0188 0.084 0.1152
Trichomonas vaginalis calmodulin, putative 0.0084 0.0326 0.0897
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.002 0.0007 0.0006
Trypanosoma brucei mitochondrial calcium uptake 1 0.0083 0.0319 0.0437
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.028
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0157 0.0687 0.0942
Leishmania major centrin, putative 0.0083 0.0319 0.0437
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0267 0.1231 0.123
Echinococcus granulosus calpain A 0.0523 0.2499 0.2498
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.0595 0.0595
Loa Loa (eye worm) prolyl oligopeptidase 0.0491 0.2343 0.2343
Schistosoma mansoni regulator of G protein signaling 0.004 0.0105 0.0105
Schistosoma mansoni Mername-AA248 (C02 family) 0.0523 0.2499 0.2498
Entamoeba histolytica cysteine proteinase, putative 0.0351 0.1646 0.5456
Brugia malayi Peroxidasin 0.0063 0.0223 0.0222
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0163 0.0715 0.0714
Echinococcus multilocularis Glycosyl transferase, family 35 0.0106 0.0436 0.0435
Toxoplasma gondii calmodulin CAM1 0.0084 0.0326 0.0447
Onchocerca volvulus Peroxidasin homolog 0.0063 0.0223 0.0305
Brugia malayi Trypsin-like protease protein 5 0.0061 0.0209 0.0209
Trypanosoma cruzi cysteine protease, putative 0.0351 0.1646 0.1645
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0105 0.0105
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Trypanosoma brucei histone deacetylase 1 0.0065 0.0233 0.0318
Brugia malayi prolyl oligopeptidase family protein 0.0491 0.2343 0.2342
Brugia malayi Cathepsin L-like precursor 0.0626 0.301 0.301
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0105 0.0105
Trypanosoma cruzi 20S proteasome subunit 0.0042 0.0116 0.0115
Schistosoma mansoni cpg binding protein 0.0091 0.0359 0.0359
Leishmania major cathepsin L-like protease 0.0724 0.3494 0.4796
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.0687 0.0686
Schistosoma mansoni regulator of G protein signaling 0.004 0.0105 0.0105
Entamoeba histolytica calcium binding family protein 0.0083 0.0319 0.1039
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.0687 0.1904
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.084 0.2697
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Giardia lamblia Cathepsin L precursor 0.0163 0.0715 0.1978
Schistosoma mansoni hypothetical protein 0.0039 0.0103 0.0102
Echinococcus multilocularis cathepsin L cysteine protease 0.0626 0.301 0.301
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0163 0.0715 0.2373
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0087 0.0339 0.0338
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.343
Echinococcus granulosus apoptotic protease activating factor 1 0.003 0.0056 0.0055
Mycobacterium ulcerans hypothetical protein 0.0061 0.0209 0.0485
Onchocerca volvulus 0.0061 0.0209 0.0286
Entamoeba histolytica hypothetical protein 0.004 0.0105 0.0328
Echinococcus granulosus histone deacetylase 1 0.0065 0.0233 0.0232
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Echinococcus granulosus proteasome prosome macropain 0.0087 0.0339 0.0338
Plasmodium falciparum serine repeat antigen 3 0.0163 0.0715 0.2373
Leishmania major cysteine peptidase A (CPA) 0.0626 0.301 0.4132
Trypanosoma brucei centrin, putative 0.0083 0.0319 0.0437
Echinococcus granulosus calcium uptake protein 1 0.0084 0.0326 0.0325
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0012 0.0011
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0042 0.0116 0.0158
Echinococcus multilocularis centrin 2 0.0083 0.0319 0.0318
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Plasmodium vivax serine-repeat antigen (SERA) 0.0163 0.0715 0.2373
Toxoplasma gondii cathepsin CPL 0.0626 0.301 0.4132
Echinococcus granulosus microtubule associated protein 2 0.1417 0.6926 0.6926
Schistosoma mansoni neuronal calcium sensor 0.0083 0.0319 0.0318
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0105 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Schistosoma mansoni hypothetical protein 0.0034 0.0077 0.0076
Trypanosoma cruzi I/6 autoantigen, putative 0.0083 0.0319 0.0318
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.343
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0012 0.0011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0012 0.0011
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2037 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0715 0.1982
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.0687 0.1904
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.0209
Plasmodium falciparum serine repeat antigen 6 0.0163 0.0715 0.2373
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.018 0.0801 0.2222
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0012 0.0011
Onchocerca volvulus Peroxidase homolog 0.0063 0.0223 0.0305
Loa Loa (eye worm) hypothetical protein 0.005 0.0155 0.0155
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0626 0.301 0.301
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0226 0.0225
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.002 0.0007 0.0006
Plasmodium vivax vivapain-3 0.0351 0.1646 0.5465
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Giardia lamblia Cathepsin B precursor 0.0163 0.0715 0.1978
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0105 0.0105
Echinococcus multilocularis calbindin 32 0.0084 0.0326 0.0325
Schistosoma mansoni cathepsin S (C01 family) 0.0163 0.0715 0.0714
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0595 0.0594
Giardia lamblia Cysteine protease 0.0163 0.0715 0.1978
Schistosoma mansoni regulator of G protein signaling 0.004 0.0105 0.0105
Schistosoma mansoni centrin-related 0.0083 0.0319 0.0318
Leishmania major kinesin, putative 0.0366 0.172 0.2361
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0523 0.2499 0.2498
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0226 0.0309
Trypanosoma brucei centrin-3 0.0083 0.0319 0.0437
Brugia malayi Histone deacetylase 1 0.0065 0.0233 0.0232
Echinococcus granulosus calpain 0.0523 0.2499 0.2498
Leishmania major calcineurin B subunit, putative 0.0083 0.0319 0.0437
Echinococcus multilocularis Tolloid protein 1 0.0045 0.0133 0.0133
Echinococcus multilocularis inhibitor of apoptosis protein 0.0039 0.0103 0.0102
Entamoeba histolytica calcium-binding protein, putative 0.0083 0.0319 0.1039
Brugia malayi EF hand family protein 0.0083 0.0319 0.0318
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0012 0.0012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0626 0.301 0.301
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1489 0.7284 0.7284
Trypanosoma brucei calpain-like protein, putative 0.0523 0.2499 0.343
Brugia malayi Papain family cysteine protease containing protein 0.0626 0.301 0.301
Echinococcus granulosus EF HAND 1 calcium binding site 0.0083 0.0319 0.0318
Schistosoma mansoni calpain-7 (C02 family) 0.0523 0.2499 0.2498
Plasmodium falciparum serine repeat antigen 7 0.0163 0.0715 0.2373
Loa Loa (eye worm) hypothetical protein 0.0159 0.0694 0.0694
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0012 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Loa Loa (eye worm) cathepsin B 0.0743 0.3587 0.3587
Trypanosoma cruzi I/6 autoantigen, putative 0.0083 0.0319 0.0318
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.343
Schistosoma mansoni calpain (C02 family) 0.0523 0.2499 0.2498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0012 0.0011
Plasmodium falciparum cysteine repeat modular protein 1 0.004 0.0109 0.0359
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0071 0.007
Brugia malayi hypothetical protein 0.0087 0.0339 0.0338
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0743 0.3587 0.4923
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.018 0.0801 0.1098
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Trichomonas vaginalis calpain, putative 0.0157 0.0687 0.1904
Echinococcus multilocularis cathepsin L 0.0351 0.1646 0.1645
Brugia malayi ecdysteroid receptor 0.0021 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0051 0.0161 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0226 0.0225
Brugia malayi Protein kinase domain containing protein 0.004 0.0109 0.0108
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0715 0.0714
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0267 0.1231 0.123
Entamoeba histolytica hypothetical protein 0.004 0.0105 0.0328
Echinococcus multilocularis expressed protein 0.0775 0.3746 0.3745
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.048 0.048
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.028
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0163 0.0715 0.0715
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0068 0.0243 0.0242
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0105 0.0105
Onchocerca volvulus 0.0061 0.0209 0.0286
Echinococcus multilocularis tissue type plasminogen activator 0.004 0.0109 0.0108
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0042 0.0116 0.0115
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Echinococcus granulosus calmodulin 0.0083 0.0319 0.0318
Giardia lamblia Proteasome subunit beta type 1 0.0068 0.0243 0.0659
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0163 0.0715 0.0714
Loa Loa (eye worm) hypothetical protein 0.1021 0.4964 0.4964
Trichomonas vaginalis centrin, putative 0.0083 0.0319 0.0877
Trypanosoma brucei calpain-like protein, putative 0.0523 0.2499 0.343
Toxoplasma gondii histone deacetylase HDAC2 0.0065 0.0233 0.0318
Mycobacterium ulcerans transglutaminase family protein 0.0035 0.0082 0.0039
Leishmania major hypothetical protein, conserved 0.0157 0.0687 0.0942
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0205 0.0205
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0012 0.0011
Echinococcus multilocularis Transglutaminase 0.0035 0.0082 0.0081
Brugia malayi Cathepsin L-like precursor 0.0626 0.301 0.301
Trypanosoma brucei centrin, putative 0.0083 0.0319 0.0437
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0095 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0012 0.0011
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.002 0.0007 0.0005
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0163 0.0715 0.0714
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.0687 0.1904
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0068 0.0243 0.0786
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.343
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0071 0.0071
Schistosoma mansoni axis inhibition protein axin 0.004 0.0105 0.0105
Brugia malayi cathepsin Z-like cysteine proteinase 0.0163 0.0715 0.0714
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0052 0.0051
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0116 0.0115
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Brugia malayi calpain D 0.0157 0.0687 0.0686
Brugia malayi proteasome subunit beta type 1 0.0068 0.0243 0.0242
Trypanosoma brucei kinesin, putative 0.0366 0.172 0.2361
Schistosoma mansoni ap endonuclease 0.0038 0.0095 0.0095
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0163 0.0715 0.2373
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.115 0.1149
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0087 0.0339 0.0338
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0608 0.2921 1
Echinococcus granulosus histone deacetylase 3 0.0065 0.0233 0.0232
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.0687 0.0686
Echinococcus multilocularis cysteine protease 0.0626 0.301 0.301
Echinococcus granulosus cathepsin L cysteine protease 0.0351 0.1646 0.1645
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0163 0.0715 0.1982
Onchocerca volvulus Dual oxidase homolog 0.0063 0.0223 0.0305
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0626 0.301 0.8391
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0715 0.0714
Chlamydia trachomatis glycogen phosphorylase 0.0106 0.0436 0.5
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0226 0.0225
Onchocerca volvulus 0.0159 0.0694 0.0951
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0188 0.0839 0.0839
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.0687 0.0686
Entamoeba histolytica hypothetical protein 0.004 0.0105 0.0328
Onchocerca volvulus 0.0626 0.301 0.4132
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0188 0.084 0.0839
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0012 0.0011
Entamoeba histolytica cysteine protease, putative 0.0163 0.0715 0.2357
Onchocerca volvulus Cell death protein 3 homolog 0.003 0.0056 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0007
Brugia malayi Papain family cysteine protease containing protein 0.0351 0.1646 0.1645
Schistosoma mansoni cathepsin C 0.0163 0.0715 0.0714
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.2498
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0012 0.0011
Plasmodium falciparum serine repeat antigen 2 0.0163 0.0715 0.2373
Entamoeba histolytica hypothetical protein, conserved 0.018 0.0801 0.2643
Echinococcus granulosus cathepsin L 0.0351 0.1646 0.1645
Brugia malayi hypothetical protein 0.004 0.0105 0.0105
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0083 0.0319 0.0318
Loa Loa (eye worm) trypsin family protein 0.0061 0.0209 0.0209
Schistosoma mansoni inhibitor of apoptosis protein 0.0039 0.0103 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.1646 0.4581
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0715 0.0714
Echinococcus granulosus geminin 0.0169 0.0747 0.0746
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.0209
Onchocerca volvulus Cathepsin F homolog 0.0626 0.301 0.4132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Entamoeba histolytica cysteine proteinase, putative 0.0626 0.301 1
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0491 0.2343 0.2342
Trypanosoma brucei protein I/6 0.0083 0.0319 0.0437
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0105 0.0105
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0136 0.0228
Leishmania major centrin, putative 0.0083 0.0319 0.0437
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0105 0.0105
Leishmania major hypothetical protein, unknown function 0.0157 0.0687 0.0942
Trypanosoma brucei calpain, putative 0.0157 0.0687 0.0942
Trypanosoma cruzi major cysteine proteinase, putative 0.0163 0.0715 0.0714
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0335 0.0335
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0319 0.0877
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Onchocerca volvulus 0.0061 0.0209 0.0286
Trypanosoma cruzi oligopeptidase b 0.0608 0.2921 0.2921
Leishmania major cathepsin L-like protease 0.0626 0.301 0.4132
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0012 0.0011
Echinococcus multilocularis programmed cell death protein 0.0083 0.0319 0.0318
Echinococcus multilocularis prolyl endopeptidase 0.1489 0.7284 0.7284
Echinococcus granulosus programmed cell death protein 0.0083 0.0319 0.0318
Echinococcus granulosus Glycosyl transferase family 35 0.0106 0.0436 0.0435
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0029 0.0094
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0068 0.0243 0.0805
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0267 0.1231 0.1689
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0715 0.1982
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0083 0.0319 0.0318
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Giardia lamblia Hypothetical protein 0.0163 0.0715 0.1978
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0012 0.0011
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0715 0.1978
Trypanosoma brucei proteasome beta 6 subunit 0.0068 0.0243 0.0333
Brugia malayi programmed cell death protein 6 0.0083 0.0319 0.0318
Brugia malayi Cathepsin L-like precursor 0.0626 0.301 0.301
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0012 0.0011
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0012 0.0011
Trichomonas vaginalis histone deacetylase, putative 0.0065 0.0233 0.0636
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0087 0.0339 0.0407
Entamoeba histolytica cysteine proteinase, putative 0.0351 0.1646 0.5456
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0595 0.0594
Leishmania major histone deacetylase, putative 0.0065 0.0233 0.0318
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0061 0.0209 0.0209
Schistosoma mansoni mitochondrial solute carrier 0.0083 0.0319 0.0318
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Loa Loa (eye worm) hypothetical protein 0.0087 0.0339 0.0339
Echinococcus multilocularis gamma secretase subunit aph 1 0.0247 0.1132 0.1131
Echinococcus granulosus calpain A 0.1471 0.7194 0.7194
Trypanosoma cruzi conserved protein 0.0157 0.0687 0.0686
Entamoeba histolytica protein kinase, putative 0.0366 0.172 0.5704
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0039 0.0103 0.0102
Brugia malayi Cell death protein 3 precursor 0.003 0.0056 0.0055
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0061 0.0209 0.0209
Onchocerca volvulus 0.0083 0.0319 0.0437
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Echinococcus granulosus gamma secretase subunit aph 1 0.0247 0.1132 0.1131
Onchocerca volvulus 0.0626 0.301 0.4132
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0012 0.0011
Leishmania major calpain protease-like protein 0.0157 0.0687 0.0942
Echinococcus granulosus dnaJ subfamily B 0.0822 0.3978 0.3978
Echinococcus granulosus cathepsin b 0.2037 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0626 0.301 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0095 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Echinococcus granulosus EF hand domain containing family member A2 0.0083 0.0319 0.0318
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0095 0.0314
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0715 0.0714
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0157 0.0687 0.0942
Trichomonas vaginalis histone deacetylase, putative 0.0065 0.0233 0.0636
Plasmodium vivax vivapain-2 0.0626 0.301 1
Entamoeba histolytica hypothetical protein 0.0163 0.0715 0.2357
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.115 0.1149
Echinococcus granulosus Dipeptidyl peptidase 9 0.0267 0.1231 0.123
Brugia malayi hypothetical protein 0.0251 0.115 0.1149
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.005 0.0049
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0083 0.0319 0.0437
Loa Loa (eye worm) calpain 5 0.0366 0.172 0.172
Loa Loa (eye worm) hypothetical protein 0.0065 0.0233 0.0233
Brugia malayi histone deacetylase 3 (HD3) 0.0065 0.0233 0.0232
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0436 0.0435
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.048 0.048
Trichomonas vaginalis calcineurin B subunit, putative 0.0084 0.0326 0.0897
Trichomonas vaginalis calmodulin-2, putative 0.0083 0.0319 0.0877
Entamoeba histolytica cysteine proteinase 2 0.0351 0.1646 0.5456
Echinococcus multilocularis cpg binding protein 0.0091 0.0359 0.0359
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0061 0.0209 0.0209
Trichomonas vaginalis calpain, putative 0.0157 0.0687 0.1904
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0163 0.0715 0.1982
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0686
Loa Loa (eye worm) hypothetical protein 0.0061 0.0209 0.0209
Brugia malayi Cytochrome P450 family protein 0.0033 0.0071 0.007
Entamoeba histolytica cysteine protease, putative 0.0163 0.0715 0.2357
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0523 0.2499 0.2498
Giardia lamblia Cathepsin L-like protease 0.0163 0.0715 0.1978
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Schistosoma mansoni histone deacetylase 0.0065 0.0233 0.0232
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0083 0.0319 0.1039
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0068 0.0243 0.0242
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0157 0.0687 0.0686
Brugia malayi proteasome subunit beta type 2 0.0042 0.0116 0.0115
Loa Loa (eye worm) hypothetical protein 0.018 0.0801 0.0801
Echinococcus multilocularis programmed cell death protein 0.0083 0.0319 0.0318
Giardia lamblia Cathepsin B precursor 0.0163 0.0715 0.1978
Plasmodium vivax cysteine repeat modular protein 1, putative 0.004 0.0109 0.0359
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0012 0.0012
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0039 0.0103 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0626 0.301 0.8391
Schistosoma mansoni hypothetical protein 0.0157 0.0687 0.0686
Entamoeba histolytica calpain family cysteine protease, putative 0.0157 0.0687 0.2265
Onchocerca volvulus 0.0626 0.301 0.4132
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0095 0.0295
Toxoplasma gondii prolyl endopeptidase 0.1489 0.7284 1
Giardia lamblia Cathepsin B precursor 0.0163 0.0715 0.1978
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0083 0.0319 0.0437
Trypanosoma cruzi hypothetical protein, conserved 0.018 0.0801 0.08
Brugia malayi hypothetical protein 0.004 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.0061 0.0209 0.0209
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0626 0.301 1
Echinococcus granulosus centrin 2 0.0083 0.0319 0.0318
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0105 0.0105
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0436 0.0435
Brugia malayi Proteasome A-type and B-type family protein 0.0087 0.0339 0.0338
Trichomonas vaginalis calcium binding protein, putative 0.0083 0.0319 0.0877
Loa Loa (eye worm) proteasome subunit beta type 2 0.0042 0.0116 0.0116
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0105 0.0105
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0105
Brugia malayi calpain family protein 1 0.1386 0.6776 0.6776
Entamoeba histolytica cysteine proteinase, putative 0.0438 0.208 0.6902
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0083 0.0319 0.1039
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0087 0.0339 0.0905
Entamoeba histolytica cysteine protease, putative 0.0351 0.1646 0.5456
Trypanosoma brucei cysteine peptidase C (CPC) 0.0743 0.3587 0.4923
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0005
Loa Loa (eye worm) blistered cuticle protein 3 0.0063 0.0223 0.0223
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0157 0.0687 0.0686
Loa Loa (eye worm) cysteine protease 0.0626 0.301 0.301
Trypanosoma cruzi kinesin, putative 0.0366 0.172 0.1719
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0715 0.1982
Trypanosoma cruzi cysteine peptidase, putative 0.0724 0.3494 0.3494
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Loa Loa (eye worm) EF hand family protein 0.0083 0.0319 0.0319
Echinococcus granulosus calpain 5 0.0523 0.2499 0.2498
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0715 0.1982
Plasmodium vivax vivapain-2 0.0626 0.301 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0026 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0247 0.1132 0.1132
Loa Loa (eye worm) histone deacetylase 7A 0.0019 0.0001 0.0001
Mycobacterium ulcerans proteasome PrcB 0.0087 0.0339 0.094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0095 0.0085
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0523 0.2499 0.2498
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0116 0.0309
Plasmodium vivax serine-repeat antigen (SERA) 0.0163 0.0715 0.2373
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0155 0.0154
Onchocerca volvulus Glycogen phosphorylase homolog 0.0106 0.0436 0.0597
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0608 0.2921 0.2921
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Trichomonas vaginalis centrin, putative 0.0083 0.0319 0.0877
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0071 0.0071
Brugia malayi Trypsin family protein 0.0061 0.0209 0.0209
Loa Loa (eye worm) proteasome subunit beta type 1 0.0068 0.0243 0.0243
Schistosoma mansoni rab 0.0083 0.0319 0.0318
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0223 0.0222
Brugia malayi cathepsin L-like cysteine proteinase 0.0163 0.0715 0.0714
Loa Loa (eye worm) hypothetical protein 0.0157 0.0687 0.0687
Entamoeba histolytica cysteine protease, putative 0.0163 0.0715 0.2357
Leishmania major cathepsin L-like protease 0.0626 0.301 0.4132
Trypanosoma cruzi kinesin, putative 0.0366 0.172 0.1719
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0267 0.1231 0.123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0351 0.1646 0.2258
Brugia malayi nuclear receptor NHR-88 0.0021 0.0012 0.0011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0165 0.0728 0.0999
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.018 0.0801 0.2222
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0061 0.0209 0.0209
Trypanosoma brucei I/6 autoantigen 0.0083 0.0319 0.0437
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.0687 0.0686
Echinococcus multilocularis neuronal calcium sensor 0.0083 0.0319 0.0318
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1469 0.7187 0.7186
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0105
Giardia lamblia Cysteine protease 0.0163 0.0715 0.1978
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0065 0.0233 0.0636
Trypanosoma cruzi histone deacetylase 1, putative 0.0065 0.0233 0.0232
Toxoplasma gondii calcium-dependent protein kinase 0.0084 0.0326 0.0447
Trichomonas vaginalis histone deacetylase, putative 0.0065 0.0233 0.0636
Echinococcus granulosus cysteine protease 0.0351 0.1646 0.1645
Giardia lamblia Hypothetical protein 0.0163 0.0715 0.1978
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2037 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0223 0.0222
Loa Loa (eye worm) hypothetical protein 0.0438 0.208 0.208
Loa Loa (eye worm) histone deacetylase 0.0019 0.0001 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.084 0.0839
Onchocerca volvulus 0.0083 0.0319 0.0437
Echinococcus granulosus expressed protein 0.0775 0.3746 0.3745
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0007 0.0005
Loa Loa (eye worm) calmodulin-like protein 0.0083 0.0319 0.0319
Toxoplasma gondii serine carboxypeptidase s28 protein 0.002 0.0007 0.0008
Giardia lamblia Cysteine protease 0.0163 0.0715 0.1978
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0223 0.0222
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0163 0.0715 0.2373
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0012 0.0011
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0136 0.0431
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0026 0.0025
Onchocerca volvulus 0.0086 0.0335 0.0459
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0116 0.0309
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Giardia lamblia Encystation-specific protease 0.0163 0.0715 0.1978
Loa Loa (eye worm) hypothetical protein 0.004 0.0109 0.0109
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0223 0.0223
Echinococcus multilocularis cathepsin L cysteine protease 0.0626 0.301 0.301
Trypanosoma brucei oligopeptidase b 0.0608 0.2921 0.401
Schistosoma mansoni hypothetical protein 0.0035 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0007
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0608 0.2921 0.2921
Brugia malayi Trypsin family protein 0.0061 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0436 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0626 0.301 0.8391
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0105 0.0105
Brugia malayi Trypsin family protein 0.0061 0.0209 0.0209
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0157 0.0687 0.0942
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0743 0.3587 0.3586
Schistosoma mansoni cercarial elastase (S01 family) 0.0061 0.0209 0.0209
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0116 0.0115
Trichomonas vaginalis calmodulin, putative 0.0083 0.0319 0.0877
Leishmania major oligopeptidase b 0.0608 0.2921 0.401
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.0595 0.0594
Plasmodium falciparum cysteine proteinase falcipain 3 0.0626 0.301 1
Trichomonas vaginalis calcium binding proteins, putative 0.0083 0.0319 0.0877
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0083 0.0319 0.0877
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.084 0.2697
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0136 0.0431
Echinococcus granulosus cathepsin L 0.0163 0.0715 0.0714
Loa Loa (eye worm) hypothetical protein 0.0188 0.0839 0.0839
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.018 0.0801 0.08
Brugia malayi fibroinase precursor 0.0163 0.0715 0.0714
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0039 0.0103 0.0102
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0371 0.1744 0.1743
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0105 0.0105
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0087 0.0339 0.0933
Loa Loa (eye worm) hypothetical protein 0.0044 0.0124 0.0124
Echinococcus granulosus calpain 7 C02 family 0.0523 0.2499 0.2498
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0105 0.0105
Trichomonas vaginalis histone deacetylase, putative 0.0065 0.0233 0.0636
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0056
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0084 0.0326 0.0325
Echinococcus multilocularis transmembrane protease serine 3 0.0061 0.0209 0.0209
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2037 1 1
Entamoeba histolytica grainin, putative 0.0084 0.0326 0.1063
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0012 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0012 0.0012
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0163 0.0715 0.2373
Loa Loa (eye worm) hypothetical protein 0.0188 0.0839 0.0839
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0071 0.007
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0226 0.0225
Echinococcus granulosus cathepsin L cysteine proteinase 0.0626 0.301 0.301
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0012 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0724 0.3494 0.4796
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0319 0.0877
Entamoeba histolytica dipeptidyl-peptidase, putative 0.018 0.0801 0.2643
Echinococcus granulosus calbindin 32 0.0084 0.0326 0.0325
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0029 0.0039
Brugia malayi steroid hormone receptor 0.0021 0.0012 0.0011
Plasmodium vivax centrin-1, putative 0.0083 0.0319 0.1058
Loa Loa (eye worm) hypothetical protein 0.0063 0.0223 0.0223
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0083 0.0319 0.0318
Trypanosoma brucei calpain-like protein, putative 0.0523 0.2499 0.343
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.018 0.0801 0.1098
Brugia malayi Cytochrome P450 family protein 0.0054 0.0177 0.0176
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0007
Brugia malayi PXA domain containing protein 0.004 0.0105 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0109 0.0108
Entamoeba histolytica histone deacetylase, putative 0.0065 0.0233 0.0752
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.0687 0.0942
Loa Loa (eye worm) fibroinase 0.0626 0.301 0.301
Echinococcus multilocularis calpain 7 (C02 family) 0.0523 0.2499 0.2498

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 10 nM Binding affinity to human somatostatin 2 receptor ChEMBL. 11212124
Ki (binding) = 10 nM Binding affinity to human somatostatin 2 receptor ChEMBL. 11212124

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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