Detailed information for compound 231053

Basic information

Technical information
  • TDR Targets ID: 231053
  • Name: 6-acetamido-N,N-dimethylhexanamide
  • MW: 200.278 | Formula: C10H20N2O2
  • H donors: 1 H acceptors: 2 LogP: 0.04 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)NCCCCCC(=O)N(C)C
  • InChi: 1S/C10H20N2O2/c1-9(13)11-8-6-4-5-7-10(14)12(2)3/h4-8H2,1-3H3,(H,11,13)
  • InChiKey: HCHJHUGRRZAAMO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-acetamido-N,N-dimethyl-hexanamide
  • 51504-52-0
  • NSC376259
  • Hexanamide, 6-(acetylamino)-N,N-dimethyl-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni calpain-7 (C02 family) 0.0503 0.469 0.4689
Toxoplasma gondii cathepsin B 0.0193 0.172 0.5485
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0536 0.4999 0.672
Echinococcus granulosus bloom syndrome protein 0.0021 0.0078 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Plasmodium falciparum thioredoxin reductase 0.0047 0.0323 0.094
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0571 0.0594
Plasmodium falciparum cysteine repeat modular protein 1 0.0021 0.0081 0.0159
Plasmodium vivax vivapain-2 0.034 0.3129 0.6662
Entamoeba histolytica cysteine proteinase, putative 0.0181 0.1608 0.5051
Plasmodium falciparum centrin-1 0.0054 0.039 0.1156
Entamoeba histolytica cysteine proteinase, putative 0.0181 0.1608 0.5051
Onchocerca volvulus 0.034 0.3129 0.6705
Echinococcus granulosus calpain A 0.0503 0.469 0.4683
Giardia lamblia Cathepsin B precursor 0.0193 0.172 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0115 0.0112
Trypanosoma brucei small myristoylated protein 1-1 0.035 0.3226 0.4344
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.2045 1
Onchocerca volvulus 0.0027 0.0131 0.0263
Loa Loa (eye worm) calpain 0.0503 0.469 0.4945
Trichomonas vaginalis esterase, putative 0.0036 0.0217 0.0692
Giardia lamblia Encystation-specific protease 0.0073 0.0571 0.3194
Trypanosoma cruzi cruzipain precursor, putative 0.0108 0.0914 0.1194
Plasmodium vivax SET domain protein, putative 0.0031 0.017 0.0336
Echinococcus multilocularis lamin 0.0027 0.0131 0.0119
Schistosoma mansoni reticulocalbin 0.0055 0.0403 0.0391
Schistosoma mansoni lamin 0.0027 0.0131 0.0119
Leishmania major DNA polymerase kappa, putative 0.0019 0.0059 0.0037
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0203 0.1819 0.2447
Echinococcus multilocularis EF hand domain containing family member A2 0.0055 0.0403 0.0391
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0217 0.0204
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0203 0.1819 0.2447
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0571 0.1825
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0689 0.6463 0.8701
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0217 0.0918
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0203 0.1819 0.2418
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.034 0.3129 1
Brugia malayi Death domain containing protein 0.0014 0.0013 0.0004
Trypanosoma brucei Calpain-like protein CALP1.3 0.0457 0.4243 0.5714
Giardia lamblia DINP protein human, muc B family 0.0019 0.0059 0.0163
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.034 0.3129 0.3296
Echinococcus granulosus neurocalcin 0.0054 0.039 0.0377
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0193 0.172 0.2284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0571 0.1825
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0894 0.4282
Entamoeba histolytica cysteine protease, putative 0.034 0.3129 1
Echinococcus multilocularis calpain 7 (C02 family) 0.0503 0.469 0.4683
Echinococcus multilocularis cathepsin L cysteine protease 0.034 0.3129 0.312
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0297 0.2714 0.3629
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0571 0.0559
Echinococcus granulosus programmed cell death protein 0.0062 0.0466 0.0454
Echinococcus granulosus cathepsin l cysteine peptidase 0.034 0.3129 0.312
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0055 0.0049
Echinococcus multilocularis dna polymerase eta 0.0044 0.0299 0.0287
Loa Loa (eye worm) programmed cell death protein 6 0.0055 0.0403 0.0416
Loa Loa (eye worm) beta-lactamase 0.0036 0.0217 0.0219
Toxoplasma gondii ABC1 family protein 0.0036 0.0217 0.0665
Onchocerca volvulus 0.0031 0.017 0.0347
Brugia malayi Pre-SET motif family protein 0.0031 0.017 0.017
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0457 0.4243 0.5697
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.1007 0.4845
Loa Loa (eye worm) hypothetical protein 0.0501 0.4662 0.4916
Echinococcus granulosus cathepsin l1 0.0232 0.2092 0.2082
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0323 0.1446
Echinococcus multilocularis tissue type plasminogen activator 0.0021 0.0081 0.0068
Trypanosoma brucei calmodulin, putative 0.0054 0.039 0.0521
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0056 0.0049
Brugia malayi calpain 5 0.025 0.2265 0.2384
Loa Loa (eye worm) glutathione reductase 0.0047 0.0323 0.0332
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.017 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0571 0.1825
Echinococcus granulosus dna polymerase kappa 0.0019 0.0059 0.0046
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0511 0.4762 0.64
Leishmania major hypothetical protein, unknown function 0.0254 0.2302 0.3071
Echinococcus granulosus EF hand domain containing family member A2 0.0055 0.0403 0.0391
Toxoplasma gondii centrin, putative 0.0054 0.039 0.122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0217 0.0692
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0131 0.0129
Leishmania major hypothetical protein, conserved 0.0025 0.0115 0.0112
Trypanosoma brucei I/6 autoantigen 0.0054 0.039 0.0521
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0571 0.056
Echinococcus granulosus calumenin 0.0055 0.0403 0.0391
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0217 0.0918
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0761 0.7151 0.9631
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Echinococcus multilocularis cathepsin L 0.0181 0.1608 0.1597
Trypanosoma brucei hypothetical protein, conserved 0.0329 0.3023 0.407
Plasmodium vivax calpain, putative 0.0503 0.469 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.2338 0.3147
Loa Loa (eye worm) TK/ROR protein kinase 0.0021 0.0081 0.0076
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0461 0.4287 0.4285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0571 0.1825
Giardia lamblia Cysteine protease 0.0073 0.0571 0.3194
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0013 0.000000019665
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0013 0.0004
Onchocerca volvulus 0.0036 0.0217 0.0446
Echinococcus multilocularis cathepsin b 0.0461 0.4287 0.4279
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0073 0.0571 0.1193
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0307
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0131 0.0129
Trypanosoma brucei calpain-like protein, putative 0.0503 0.469 0.6316
Trypanosoma cruzi cysteine peptidase, putative 0.0387 0.3572 0.479
Brugia malayi Cathepsin L-like precursor 0.034 0.3129 0.3296
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0022 0.0009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0004
Trypanosoma cruzi calmodulin, putative 0.0054 0.039 0.0484
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0566 0.5291 0.7116
Mycobacterium ulcerans beta-lactamase 0.0036 0.0217 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0174 0.0528
Entamoeba histolytica cysteine protease, putative 0.0073 0.0571 0.1677
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.039 0.1245
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0032 0.0073
Echinococcus granulosus calbindin 32 0.0055 0.0403 0.0391
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0059 0.0189
Echinococcus granulosus centrin 2 0.0054 0.039 0.0377
Plasmodium vivax centrin-1, putative 0.0054 0.039 0.0805
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0217 0.0918
Schistosoma mansoni calmodulin related calcium binding protein 0.0054 0.039 0.0378
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0217 0.0204
Echinococcus multilocularis calcium uptake protein 1 0.0055 0.0403 0.0391
Echinococcus granulosus calpain 0.0503 0.469 0.4683
Schistosoma mansoni cathepsin s 0.0108 0.0914 0.0904
Leishmania major hypothetical protein, conserved 0.0203 0.1819 0.2418
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0461 0.4287 0.4285
Echinococcus granulosus calpain 7 C02 family 0.0503 0.469 0.4683
Trypanosoma brucei calpain-like protein, putative 0.0503 0.469 0.6316
Loa Loa (eye worm) hypothetical protein 0.0036 0.0217 0.0219
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0323 0.0311
Loa Loa (eye worm) RecQ helicase 0.0021 0.0078 0.0073
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.1007 1
Loa Loa (eye worm) EF hand family protein 0.0054 0.039 0.0402
Giardia lamblia Cysteine protease 0.0073 0.0571 0.3194
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0439 0.4076 0.5471
Trypanosoma cruzi conserved protein 0.0465 0.4326 0.581
Toxoplasma gondii cathepsin CPC1 0.0073 0.0571 0.1801
Schistosoma mansoni Mername-AA248 (C02 family) 0.0503 0.469 0.4689
Trypanosoma brucei Calpain-like protein 1.2 0.0598 0.5593 0.7533
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0297 0.2714 0.3654
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0278 0.2535 0.3387
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0254 0.2302 0.3098
Echinococcus granulosus tissue type plasminogen activator 0.0021 0.0081 0.0068
Trypanosoma brucei calpain, putative 0.0511 0.4762 0.6414
Trypanosoma brucei calpain, putative 0.0254 0.2302 0.3098
Toxoplasma gondii cathepsin CPL 0.034 0.3129 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.034 0.3129 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0036 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0571 0.1825
Loa Loa (eye worm) hypothetical protein 0.0073 0.0571 0.0594
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0217 0.0918
Echinococcus granulosus cathepsin L cysteine protease 0.0181 0.1608 0.1597
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0056 1
Schistosoma mansoni hypothetical protein 0.0167 0.1474 0.1465
Echinococcus granulosus lamin dm0 0.0027 0.0131 0.0119
Entamoeba histolytica calpain large subunit domain III containing protein 0.025 0.2265 0.719
Entamoeba histolytica grainin, putative 0.0055 0.0403 0.113
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0203 0.1819 0.2447
Trypanosoma cruzi cysteine peptidase, putative 0.034 0.3129 0.419
Echinococcus granulosus cathepsin b 0.0461 0.4287 0.4279
Leishmania major programmed cell death 6 protein-like protein 0.0054 0.039 0.0484
Leishmania major hypothetical protein, conserved 0.0203 0.1819 0.2418
Trypanosoma cruzi hypothetical protein, conserved 0.0329 0.3023 0.4046
Echinococcus granulosus dna polymerase eta 0.0044 0.0299 0.0287
Loa Loa (eye worm) hypothetical protein 0.1004 0.9474 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0043
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0511 0.4762 0.6414
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Entamoeba histolytica calmodulin, putative 0.0054 0.039 0.1087
Brugia malayi Thioredoxin reductase 0.0047 0.0323 0.0332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Trichomonas vaginalis hypothetical protein 0.0254 0.2302 0.7356
Echinococcus multilocularis cathepsin l cysteine peptidase 0.034 0.3129 0.312
Echinococcus multilocularis cpg binding protein 0.006 0.045 0.0437
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0073 0.0571 0.056
Mycobacterium tuberculosis Probable reductase 0.0106 0.0894 0.4282
Schistosoma mansoni calpain-7 (C02 family) 0.0503 0.469 0.4689
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0503 0.469 0.6302
Trichomonas vaginalis calpain, putative 0.0254 0.2302 0.7356
Schistosoma mansoni calpain-2 (C02 family) 0.0254 0.2302 0.2295
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0254 0.2302 0.7356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Echinococcus granulosus cathepsin b 0.0461 0.4287 0.4279
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Plasmodium falciparum serine repeat antigen 4 0.0073 0.0571 0.1741
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0461 0.4287 0.4285
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0148 0.0136
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0115 0.0268
Echinococcus granulosus neuronal calcium sensor 0.0054 0.039 0.0377
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0055 0.0042
Schistosoma mansoni lamin 0.0027 0.0131 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0181 0.1608 0.5139
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0761 0.7151 0.9631
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0054 0.039 0.0377
Echinococcus multilocularis calpain 5 0.0503 0.469 0.4683
Trypanosoma cruzi hypothetical protein, conserved 0.0203 0.1819 0.2418
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0571 0.3194
Leishmania major calmodulin-like protein 0.0054 0.039 0.0484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Leishmania major cathepsin L-like protease 0.0387 0.3572 0.479
Plasmodium falciparum cysteine proteinase falcipain 2a 0.034 0.3129 1
Plasmodium vivax glutathione reductase, putative 0.0047 0.0323 0.0662
Brugia malayi EF hand family protein 0.0055 0.0403 0.0416
Brugia malayi CXXC zinc finger family protein 0.0057 0.0419 0.0433
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0032
Giardia lamblia Cathepsin B precursor 0.0073 0.0571 0.3194
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.017 0.0158
Trypanosoma brucei calpain-like protein, putative 0.0761 0.7151 0.9632
Brugia malayi Cathepsin L-like precursor 0.034 0.3129 0.3296
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0078 0.0073
Schistosoma mansoni centrin 0.0054 0.039 0.0378
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0059 0.0046
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0299 0.04
Giardia lamblia Cathepsin L precursor 0.0073 0.0571 0.3194
Trypanosoma brucei centrin, putative 0.0054 0.039 0.0521
Brugia malayi calpain D 0.0254 0.2302 0.2422
Onchocerca volvulus 0.0057 0.0419 0.088
Trypanosoma brucei caltractin, putative 0.0062 0.0466 0.0624
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0457 0.4243 0.5697
Plasmodium vivax vivapain-3 0.0181 0.1608 0.341
Plasmodium vivax unspecified product 0.0181 0.1608 0.341
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.034 0.3129 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0254 0.2302 0.7356
Echinococcus multilocularis musashi 0.0027 0.0131 0.0119
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0789 0.7423 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0032 0.0024
Trypanosoma brucei Calpain-like protein 2 0.058 0.5426 0.7308
Loa Loa (eye worm) calpain 5 0.025 0.2265 0.2384
Brugia malayi beta-lactamase family protein 0.0036 0.0217 0.0219
Plasmodium vivax vivapain-1 0.0181 0.1608 0.341
Plasmodium vivax unspecified product 0.0108 0.0914 0.1927
Leishmania major calpain family cysteine protease-like protein 0.0457 0.4243 0.5697
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0108 0.0914 0.0956
Entamoeba histolytica protein kinase, putative 0.025 0.2265 0.719
Schistosoma mansoni hypothetical protein 0.0254 0.2302 0.2295
Onchocerca volvulus Cathepsin L homolog 0.034 0.3129 0.6705
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Entamoeba histolytica hypothetical protein, conserved 0.0055 0.0403 0.113
Schistosoma mansoni neuronal calcium sensor 0.0054 0.039 0.0378
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0073 0.0571 0.1193
Echinococcus multilocularis calbindin 32 0.0055 0.0403 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0571 0.1825
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0571 0.3194
Loa Loa (eye worm) hypothetical protein 0.075 0.705 0.7439
Leishmania major i/6 autoantigen-like protein 0.0054 0.039 0.0484
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0032 0.0039
Plasmodium falciparum calpain 0.0254 0.2302 0.7329
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0059 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0329 0.3023 0.9661
Brugia malayi cathepsin L-like precursor 0.0232 0.2092 0.2201
Schistosoma mansoni thyroid hormone receptor 0.0134 0.1159 0.1149
Brugia malayi beta-lactamase 0.0036 0.0217 0.0219
Brugia malayi calpain family protein 1 0.1004 0.9474 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.017 0.0517
Loa Loa (eye worm) calmodulin-like protein 0.0054 0.039 0.0402
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0059 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Entamoeba histolytica cysteine proteinase, putative 0.0181 0.1608 0.5051
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0457 0.4243 0.5714
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.017 0.0158
Schistosoma mansoni hypothetical protein 0.0054 0.039 0.0378
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0571 0.1825
Onchocerca volvulus 0.0036 0.0217 0.0446
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1608 0.2163
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0115 0.0112
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0503 0.469 0.6302
Leishmania major hypothetical protein, conserved 0.0021 0.0081 0.0067
Schistosoma mansoni rab 0.0054 0.039 0.0378
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0299 0.0362
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0181 0.1608 0.2133
Onchocerca volvulus 0.034 0.3129 0.6705
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0257 0.2338 0.3147
Entamoeba histolytica cysteine protease, putative 0.0073 0.0571 0.1677
Brugia malayi Calmodulin-like protein 0.0054 0.039 0.0402
Onchocerca volvulus 0.0027 0.0131 0.0263
Echinococcus granulosus calpain 5 0.0503 0.469 0.4683
Echinococcus multilocularis neuronal calcium sensor 0.0054 0.039 0.0377
Loa Loa (eye worm) hypothetical protein 0.0054 0.039 0.0402
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0073 0.0571 0.1677
Leishmania major small myristoylated protein-2 0.0638 0.598 0.8048
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.2338 0.3147
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0073 0.0571 0.1741
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0073 0.0571 0.3194
Trichomonas vaginalis calcineurin B subunit, putative 0.0054 0.039 0.1245
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Entamoeba histolytica calmodulin, putative 0.0054 0.039 0.1087
Trichomonas vaginalis calmodulin, putative 0.0054 0.039 0.1245
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.1064 0.1052
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0217 0.0918
Loa Loa (eye worm) hypothetical protein 0.0108 0.0914 0.0956
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0032 0.5
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Onchocerca volvulus 0.034 0.3129 0.6705
Plasmodium falciparum cysteine proteinase falcipain 2b 0.034 0.3129 1
Giardia lamblia Cathepsin L precursor 0.0073 0.0571 0.3194
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.2338 0.3147
Schistosoma mansoni hypothetical protein 0.0167 0.1474 0.1465
Toxoplasma gondii EF hand domain-containing protein 0.0054 0.039 0.122
Trypanosoma cruzi hypothetical protein, conserved 0.0203 0.1819 0.2418
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0032 0.0039
Brugia malayi Cathepsin L-like precursor 0.034 0.3129 0.3296
Trichomonas vaginalis conserved hypothetical protein 0.0254 0.2302 0.7356
Loa Loa (eye worm) calpain family protein 1 0.0754 0.7086 0.7477
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0073 0.0571 0.1825
Trichomonas vaginalis calcium binding protein, putative 0.0054 0.039 0.1245
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0059 0.0037
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0747 0.7017 0.9451
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0598 0.5593 0.7523
Loa Loa (eye worm) hypothetical protein 0.0313 0.2867 0.302
Trypanosoma brucei centrin-3 0.0062 0.0466 0.0624
Toxoplasma gondii calmodulin CAM1 0.0055 0.0403 0.1263
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0022 0.0009
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0073 0.0571 0.056
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0894 0.4282
Trypanosoma cruzi hypothetical protein, conserved 0.0329 0.3023 0.4046
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0115 0.0217
Giardia lamblia Hypothetical protein 0.0073 0.0571 0.3194
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0115 0.0112
Schistosoma mansoni cpg binding protein 0.0057 0.0419 0.0407
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0073 0.0571 0.056
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.017
Onchocerca volvulus Cathepsin F homolog 0.034 0.3129 0.6705
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Echinococcus multilocularis neurocalcin 0.0054 0.039 0.0377
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0059 0.0053
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0056 0.0032
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0032 0.0073
Brugia malayi EF hand family protein 0.0054 0.039 0.0402
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0457 0.4243 0.5697
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0323 0.0394
Leishmania major hypothetical protein, conserved 0.0329 0.3023 0.4046
Leishmania major centrin, putative 0.0054 0.039 0.0484
Onchocerca volvulus 0.034 0.3129 0.6705
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0059 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.2092 0.6686
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0056 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0689 0.6464 0.8707
Giardia lamblia Cathepsin B precursor 0.0193 0.172 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0217 0.0204
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0689 0.6464 0.8702
Leishmania major cysteine peptidase A (CPA) 0.034 0.3129 0.419
Leishmania major centrin, putative 0.0054 0.039 0.0484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Echinococcus multilocularis cathepsin L cysteine protease 0.034 0.3129 0.312
Onchocerca volvulus 0.034 0.3129 0.6705
Loa Loa (eye worm) hypothetical protein 0.0026 0.0127 0.0124
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0059 0.0046
Plasmodium falciparum serine repeat antigen 5 0.0073 0.0571 0.1741
Schistosoma mansoni hypothetical protein 0.0051 0.0365 0.0353
Trypanosoma brucei cysteine peptidase, putative 0.0457 0.4243 0.5714
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0571 0.0594
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0073 0.0571 0.1825
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0073 0.0571 0.1825
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Entamoeba histolytica calcium-binding protein, putative 0.0054 0.039 0.1087
Echinococcus granulosus cysteine protease 0.0181 0.1608 0.1597
Echinococcus multilocularis calumenin 0.0055 0.0403 0.0391
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0254 0.2302 0.7356
Loa Loa (eye worm) papain family cysteine protease containing protein 0.034 0.3129 0.3296
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0054 0.039 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Trypanosoma cruzi calmodulin, putative 0.0054 0.039 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0073 0.0571 0.1825
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.017 0.0158
Trypanosoma cruzi centrin, putative 0.0062 0.0466 0.0587
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0566 0.5291 0.7116
Toxoplasma gondii centrin 0.0054 0.039 0.122
Onchocerca volvulus Cathepsin L homolog 0.034 0.3129 0.6705
Echinococcus granulosus cathepsin L 0.0181 0.1608 0.1597
Echinococcus multilocularis cysteine protease 0.034 0.3129 0.312
Trichomonas vaginalis calmodulin, putative 0.0062 0.0466 0.1489
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1004 0.9474 0.9486
Toxoplasma gondii kringle domain-containing protein 0.0021 0.0081 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Trypanosoma cruzi centrin, putative 0.0062 0.0466 0.0587
Trichomonas vaginalis calcium binding protein, putative 0.0054 0.039 0.1245
Onchocerca volvulus 0.0021 0.0081 0.0155
Echinococcus multilocularis centrin 2 0.0054 0.039 0.0377
Schistosoma mansoni neuronal calcium sensor 0.0054 0.039 0.0378
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0566 0.5291 0.7116
Leishmania major calmodulin-like protein 0.0054 0.039 0.0484
Trichomonas vaginalis calpain, putative 0.0254 0.2302 0.7356
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0013 0.0005
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0761 0.7151 0.9631
Trichomonas vaginalis myosin light chain 1, putative 0.0054 0.039 0.1245
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.0178
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0894 0.4282
Trypanosoma brucei hypothetical protein, conserved 0.0054 0.039 0.0521
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0181 0.1608 0.1599
Leishmania major cathepsin L-like protease 0.034 0.3129 0.419
Giardia lamblia Cathepsin B precursor 0.0193 0.172 1
Plasmodium falciparum serine repeat antigen 8 0.0073 0.0571 0.1741
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0059 0.0037
Brugia malayi Cathepsin L-like precursor 0.0232 0.2092 0.2201
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0032 0.0039
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0059 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0217 0.025
Leishmania major calpain protease-like protein 0.0254 0.2302 0.3071
Schistosoma mansoni mitochondrial solute carrier 0.0054 0.039 0.0378
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0073 0.0571 0.1741
Leishmania major centrin, putative,caltractin, putative 0.0054 0.039 0.0484
Loa Loa (eye worm) hypothetical protein 0.0021 0.0081 0.0076
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0203 0.1819 0.2418
Echinococcus granulosus dnaJ subfamily B 0.0406 0.3755 0.3747
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Leishmania major hypothetical protein, conserved 0.0203 0.1819 0.2418
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0257 0.2338 0.3147
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0054 0.039 0.0484
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0297 0.2714 0.3629
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0217 0.0288
Giardia lamblia Cathepsin L precursor 0.0073 0.0571 0.3194
Leishmania major calmodulin, putative 0.0054 0.039 0.0484
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0419 0.0433
Entamoeba histolytica calcium binding family protein 0.0054 0.039 0.1087
Toxoplasma gondii preprocathepsin c precursor, putative 0.0073 0.0571 0.1801
Schistosoma mansoni hypothetical protein 0.0124 0.1064 0.1054
Entamoeba histolytica cysteine protease, putative 0.0073 0.0571 0.1677
Loa Loa (eye worm) hypothetical protein 0.0036 0.0217 0.0219
Leishmania major META domain containing protein 0.0203 0.1819 0.2418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0217 0.0692
Giardia lamblia Hypothetical protein 0.0073 0.0571 0.3194
Trichomonas vaginalis calcium binding protein, putative 0.0062 0.0466 0.1489
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0019
Mycobacterium ulcerans lipase LipD 0.0036 0.0217 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0439 0.4076 0.5489
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.1064 0.1052
Schistosoma mansoni intermediate filament proteins 0.0027 0.0131 0.0119
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.5426 0.7297
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0131 0.0129
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0323 0.0332
Trypanosoma cruzi centrin-3 0.0062 0.0466 0.0587
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0059 0.0012
Trichomonas vaginalis calmodulin, putative 0.0054 0.039 0.1245
Schistosoma mansoni hypothetical protein 0.0021 0.0081 0.0068
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0022 0.0009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0598 0.5593 0.7523
Trichomonas vaginalis centrin, putative 0.0054 0.039 0.1245
Leishmania major small myristoylated protein-1 0.035 0.3226 0.4322
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0217 0.0692
Brugia malayi glutathione reductase 0.0047 0.0323 0.0332
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0059 0.0076
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0073 0.0571 0.056
Trypanosoma cruzi cysteine proteinase, putative 0.0181 0.1608 0.2133
Onchocerca volvulus 0.0232 0.2092 0.4477
Loa Loa (eye worm) hypothetical protein 0.0232 0.2092 0.2201
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0012 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0747 0.7017 0.9451
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.017 0.0158
Leishmania major hypothetical protein, conserved 0.0036 0.0217 0.025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0217 0.0918
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.2338 0.312
Trypanosoma brucei centrin, putative 0.0054 0.039 0.0521
Loa Loa (eye worm) ctsf protein 0.034 0.3129 0.3296
Trypanosoma cruzi hypothetical protein, conserved 0.0203 0.1819 0.2418
Toxoplasma gondii cathepsin CPC2 0.0073 0.0571 0.1801
Leishmania major kinesin, putative 0.025 0.2265 0.3022
Onchocerca volvulus 0.034 0.3129 0.6705
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0571 0.1825
Echinococcus multilocularis cathepsin l cysteine peptidase 0.034 0.3129 0.312
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0747 0.7017 0.9451
Trypanosoma cruzi small myristoylated protein 1-2 0.035 0.3226 0.4322
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Plasmodium vivax vivapain-2 0.034 0.3129 0.6662
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0054 0.039 0.0378
Trypanosoma cruzi cysteine peptidase, putative 0.0181 0.1608 0.2133
Loa Loa (eye worm) calpain D 0.0254 0.2302 0.2422
Trichomonas vaginalis calmodulin, putative 0.0054 0.039 0.1245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Trypanosoma cruzi caltractin, putative 0.0054 0.039 0.0484
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0115 0.0151
Echinococcus granulosus Ankyrin 0.0014 0.0014 0.0001
Schistosoma mansoni calpain C (C02 family) 0.0503 0.469 0.4689
Trichomonas vaginalis calcium binding protein, putative 0.0054 0.039 0.1245
Echinococcus multilocularis calpain A 0.1059 1 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0689 0.6464 0.8702
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0217 0.0435
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0013 0.000000019665
Echinococcus multilocularis cysteine protease 0.034 0.3129 0.312
Toxoplasma gondii calcium-dependent protein kinase 0.0055 0.0403 0.1263
Loa Loa (eye worm) hypothetical protein 0.0036 0.0217 0.0219
Giardia lamblia Cathepsin B precursor 0.0073 0.0571 0.3194
Trypanosoma cruzi cysteine peptidase, putative 0.0387 0.3572 0.479
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0055 0.0403 0.0391
Brugia malayi cathepsin Z-like cysteine proteinase 0.0073 0.0571 0.0594
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0022 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.039 0.1245
Echinococcus multilocularis cathepsin L 0.0073 0.0571 0.0559
Schistosoma mansoni cathepsin S (C01 family) 0.0073 0.0571 0.056
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0571 0.1825
Schistosoma mansoni DNA polymerase eta 0.0044 0.0299 0.0287
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0571 0.056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0571 0.1825
Leishmania major small myristoylated protein 4, putative 0.0552 0.5156 0.6932
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0056 0.0141
Trypanosoma brucei cysteine peptidase C (CPC) 0.0193 0.172 0.2314
Onchocerca volvulus 0.0235 0.2123 0.4543
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0203 0.1819 0.2418
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0457 0.4243 0.5697
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Trypanosoma brucei protein I/6 0.0054 0.039 0.0521
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0073 0.0571 0.1193
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0054 0.039 0.1245
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0503 0.469 0.6302
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0571 0.056
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0552 0.5156 0.6932
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0073 0.0571 0.1677
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0217 0.025
Brugia malayi calpain family protein 1 0.1004 0.9474 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.0091
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.0178
Plasmodium falciparum serine repeat antigen 9 0.0073 0.0571 0.1741
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0203 0.1819 0.2447
Plasmodium falciparum cysteine proteinase falcipain 1 0.0181 0.1608 0.5089
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.017 0.0158
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0071
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0571 0.056
Schistosoma mansoni calmodulin 0.0054 0.039 0.0378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0054 0.039 0.0484
Brugia malayi Cathepsin L-like precursor 0.034 0.3129 0.3296
Plasmodium vivax serine-repeat antigen (SERA) 0.0073 0.0571 0.1193
Echinococcus multilocularis programmed cell death protein 0.0062 0.0466 0.0454
Schistosoma mansoni thyroid hormone receptor 0.0134 0.1159 0.1149
Loa Loa (eye worm) hypothetical protein 0.0036 0.0217 0.0219
Trypanosoma cruzi cruzipain precursor, putative 0.0387 0.3572 0.479
Leishmania major hypothetical protein, conserved 0.0203 0.1819 0.2418
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0217 0.0918
Trypanosoma cruzi cysteine proteinase, putative 0.0181 0.1608 0.2133
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0073 0.0571 0.1193
Schistosoma mansoni cathepsin F (C01 family) 0.034 0.3129 0.3124
Loa Loa (eye worm) cysteine protease 0.034 0.3129 0.3296
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0254 0.2302 0.7356
Brugia malayi Cathepsin L-like precursor 0.0232 0.2092 0.2201
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0059 0.0053
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0571 0.0594
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0019
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1058 0.9987 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0181 0.1608 0.2163
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.1036 0.1026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0789 0.7423 1
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0013 0.0005
Brugia malayi cathepsin L precursor 0.0073 0.0571 0.0594
Echinococcus multilocularis calpain family protein 1, d 0.0754 0.7086 0.7082
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0022 0.0009
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0054 0.0072
Trypanosoma brucei calmodulin, putative 0.0055 0.0403 0.0539
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0193 0.172 0.5498
Giardia lamblia Cathepsin L precursor 0.0073 0.0571 0.3194
Entamoeba histolytica cysteine proteinase 1, putative 0.0181 0.1608 0.5051
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0053 0.0046
Trichomonas vaginalis calpain, putative 0.0254 0.2302 0.7356
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0108 0.0914 0.0956
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Echinococcus granulosus EF hand domain containing family member A2 0.0054 0.039 0.0377
Loa Loa (eye worm) hypothetical protein 0.0036 0.0217 0.0219
Toxoplasma gondii thioredoxin reductase 0.0047 0.0323 0.1006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.017 0.0158
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.003
Trypanosoma cruzi calmodulin, putative 0.0054 0.039 0.0484
Giardia lamblia Cathepsin L-like protease 0.0073 0.0571 0.3194
Mycobacterium tuberculosis Conserved protein 0.0036 0.0217 0.0918
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0217 0.0219
Leishmania major cathepsin L-like protease 0.0387 0.3572 0.479
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0059 0.0136
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0457 0.4243 0.5697
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Trichomonas vaginalis calmodulin, putative 0.0054 0.039 0.1245
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0323 0.0311
Echinococcus granulosus cathepsin L cysteine proteinase 0.034 0.3129 0.312
Entamoeba histolytica hypothetical protein 0.0073 0.0571 0.1677
Brugia malayi Cathepsin L-like precursor 0.034 0.3129 0.3296
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0054 0.039 0.0377
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0054 0.039 0.0521
Plasmodium vivax serine-repeat antigen (SERA) 0.0073 0.0571 0.1193
Plasmodium falciparum serine repeat antigen 3 0.0073 0.0571 0.1741
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0174 0.0192
Brugia malayi Papain family cysteine protease containing protein 0.0181 0.1608 0.1689
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0055 0.0042
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0059 0.1485
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0073 0.0571 0.1193
Brugia malayi hypothetical protein 0.0025 0.0115 0.0112
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0056 0.0049
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0254 0.2302 0.7356
Leishmania major calmodulin, putative 0.0054 0.039 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0571 0.1825
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0598 0.5593 0.7523
Loa Loa (eye worm) calpain family protein 1 0.1004 0.9474 1
Echinococcus granulosus geminin 0.0167 0.1474 0.1463
Entamoeba histolytica cysteine proteinase, putative 0.034 0.3129 1
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0059 0.1485
Onchocerca volvulus 0.0501 0.4662 1
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0203 0.1819 0.2418
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0217 0.0219
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Brugia malayi intermediate filament protein 0.0027 0.0131 0.0129
Leishmania major DNA polymerase eta, putative 0.0031 0.0174 0.0192
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0299 0.0307
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0054 0.039 0.1087
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.1851 0.1946
Echinococcus multilocularis calpain 0.0503 0.469 0.4683
Entamoeba histolytica cysteine protease, putative 0.0073 0.0571 0.1677
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0078 0.0251
Loa Loa (eye worm) cathepsin B 0.0193 0.172 0.1808
Schistosoma mansoni hypothetical protein 0.0054 0.039 0.0378
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0439 0.4076 0.5471
Plasmodium falciparum serine repeat antigen 2 0.0073 0.0571 0.1741
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0761 0.7151 0.9631
Trichomonas vaginalis calmodulin-2, putative 0.0054 0.039 0.1245
Echinococcus granulosus calcium uptake protein 1 0.0055 0.0403 0.0391
Loa Loa (eye worm) hypothetical protein 0.0036 0.0217 0.0219
Trypanosoma brucei calpain-like protein, putative 0.0503 0.469 0.6316
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0073 0.0571 0.1193
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0571 0.3194
Trichomonas vaginalis calcium binding proteins, putative 0.0054 0.039 0.1245
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0078 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0081 0.0067
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0403 0.0833
Schistosoma mansoni calmodulin 0.0054 0.039 0.0378
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0013 0.0004
Echinococcus granulosus cpg binding protein 0.006 0.045 0.0437
Giardia lamblia Cysteine protease 0.0073 0.0571 0.3194
Onchocerca volvulus 0.0055 0.0403 0.0847
Loa Loa (eye worm) hypothetical protein 0.0073 0.0571 0.0594
Schistosoma mansoni ef hand domain family member A2 0.0054 0.039 0.0378
Schistosoma mansoni calpain (C02 family) 0.0503 0.469 0.4689
Echinococcus granulosus EF HAND 1 calcium binding site 0.0054 0.039 0.0377
Brugia malayi calpain 7 0.0503 0.469 0.4945
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0217 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.1007 0.4845
Leishmania major hypothetical protein, conserved 0.0465 0.4326 0.581
Brugia malayi Cathepsin L-like precursor 0.034 0.3129 0.3296
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.0077
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0073 0.0571 0.0594
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0073 0.0571 0.0594
Entamoeba histolytica cysteine proteinase, putative 0.034 0.3129 1
Leishmania major phospholipase c-like protein 0.0054 0.039 0.0484
Brugia malayi Protein kinase domain containing protein 0.0021 0.0081 0.0076
Loa Loa (eye worm) hypothetical protein 0.0232 0.2092 0.2201
Brugia malayi cathepsin B-like cysteine proteinase 0.0461 0.4287 0.4519
Leishmania major calcineurin B subunit, putative 0.0054 0.039 0.0484
Entamoeba histolytica cysteine proteinase 2 0.0181 0.1608 0.5051
Trichomonas vaginalis centrin, putative 0.0054 0.039 0.1245
Trypanosoma cruzi kinesin, putative 0.025 0.2265 0.3022
Echinococcus multilocularis cathepsin b 0.0461 0.4287 0.4279
Giardia lamblia Cathepsin L-like protease 0.0073 0.0571 0.3194
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0021 0.0081 0.0145
Echinococcus granulosus cathepsin l1 0.034 0.3129 0.312
Brugia malayi programmed cell death protein 6 0.0054 0.039 0.0402
Echinococcus granulosus intermediate filament protein 0.0027 0.0131 0.0119
Schistosoma mansoni reticulocalbin 0.0054 0.039 0.0378
Leishmania major hypothetical protein, conserved 0.0203 0.1819 0.2418
Brugia malayi calcium-binding protein 0.0054 0.039 0.0402
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0181 0.1608 0.1599
Trypanosoma cruzi cysteine protease, putative 0.0181 0.1608 0.2133
Trichomonas vaginalis calmodulin, putative 0.0055 0.0403 0.1288
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1058 0.9987 0.9987
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.1007 0.4845
Echinococcus granulosus calmodulin 0.0054 0.039 0.0377
Plasmodium falciparum serine repeat antigen 6 0.0073 0.0571 0.1741
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0059 0.0076
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0032 0.0101
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0073 0.0571 0.1193
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0013 0.0008
Trypanosoma brucei conserved protein 0.0212 0.1902 0.2559
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0789 0.7423 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0789 0.7423 1
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.3755 0.3747
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0254 0.2302 0.7356
Trypanosoma brucei mitochondrial calcium uptake 1 0.0054 0.039 0.0521
Trypanosoma cruzi major cysteine proteinase, putative 0.0073 0.0571 0.073
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0457 0.4243 0.5697
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0503 0.469 0.6302
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0203 0.1819 0.2447
Giardia lamblia Cathepsin B precursor 0.0073 0.0571 0.3194
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0457 0.4243 0.5697
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0571 0.1825
Leishmania major hypothetical protein, conserved 0.0055 0.0403 0.0502
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0217 0.0918
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0217 0.0692
Schistosoma mansoni cathepsin F (C01 family) 0.034 0.3129 0.3124
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0457 0.4243 0.5697
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0894 0.8565
Loa Loa (eye worm) hypothetical protein 0.0073 0.0571 0.0594
Echinococcus multilocularis Ankyrin 0.0014 0.0014 0.0001
Trichomonas vaginalis calmodulin, putative 0.0054 0.039 0.1245
Giardia lamblia Cathepsin L precursor 0.0073 0.0571 0.3194
Brugia malayi Protein kinase domain containing protein 0.0014 0.0013 0.0004
Brugia malayi cathepsin F-like cysteine proteinase 0.0108 0.0914 0.0956
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0439 0.4076 0.5471
Trichomonas vaginalis calcineurin B subunit, putative 0.0055 0.0403 0.1288
Trypanosoma cruzi unspecified product 0.035 0.3226 0.4322
Trypanosoma cruzi kinesin, putative 0.025 0.2265 0.3022
Echinococcus multilocularis EF hand domain containing family member A2 0.0054 0.039 0.0377
Trypanosoma cruzi I/6 autoantigen, putative 0.0054 0.039 0.0484
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0078 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0203 0.1819 0.2418
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0457 0.4243 0.5697
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0689 0.6463 0.8701
Mycobacterium ulcerans hypothetical protein 0.0036 0.0217 1
Loa Loa (eye worm) hypothetical protein 0.0232 0.2092 0.2201
Plasmodium vivax unspecified product 0.0073 0.0571 0.1193
Loa Loa (eye worm) hypothetical protein 0.0108 0.0914 0.0956
Brugia malayi Papain family cysteine protease containing protein 0.0181 0.1608 0.1689
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0254 0.2302 0.3098
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0439 0.4076 0.5471
Loa Loa (eye worm) fibroinase 0.034 0.3129 0.3296
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0203 0.1819 0.2447
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0761 0.7151 0.9631
Trypanosoma brucei unspecified product 0.0019 0.0059 0.0076
Leishmania major trypanothione reductase 0.0047 0.0323 0.0394
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0054 0.039 0.0805
Leishmania major hypothetical protein, conserved 0.0203 0.1819 0.2418
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0193 0.172 0.2284
Brugia malayi cathepsin L-like cysteine proteinase 0.0073 0.0571 0.0594
Giardia lamblia Cysteine protease 0.0073 0.0571 0.3194
Echinococcus multilocularis calmodulin 0.0054 0.039 0.0377
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.0914 0.1194
Trypanosoma cruzi I/6 autoantigen, putative 0.0054 0.039 0.0484
Loa Loa (eye worm) hypothetical protein 0.0073 0.0571 0.0594
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Brugia malayi calpain 5 0.0254 0.2302 0.2422
Entamoeba histolytica cysteine protease, putative 0.0073 0.0571 0.1677
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1058 0.9987 1
Toxoplasma gondii EFHC1, putative 0.0054 0.039 0.122
Echinococcus multilocularis hypothetical protein 0.0503 0.469 0.4683
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0054 0.039 0.0484
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0217 0.0692
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0054 0.039 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0181 0.1608 0.5139
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1058 0.9987 0.9987
Leishmania major hypothetical protein, conserved 0.0054 0.039 0.0484
Schistosoma mansoni cathepsin C 0.0073 0.0571 0.056
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0059 0.0189
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0059 0.0037
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0073 0.0571 0.0594
Onchocerca volvulus 0.034 0.3129 0.6705
Entamoeba histolytica cysteine proteinase, putative 0.0181 0.1608 0.5051
Leishmania major cathepsin L-like protease 0.0387 0.3572 0.479
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0073 0.0571 0.1193
Trichomonas vaginalis set domain proteins, putative 0.0235 0.2122 0.678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.2092 0.6686
Plasmodium falciparum glutathione reductase 0.0047 0.0323 0.094
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0571 0.0559
Plasmodium falciparum serine repeat antigen 1 0.0073 0.0571 0.1741
Schistosoma mansoni cathepsin F (C01 family) 0.0232 0.2092 0.2085
Entamoeba histolytica grainin 2 0.0062 0.0466 0.1335
Trypanosoma brucei hypothetical protein 0.0511 0.4762 0.6414
Onchocerca volvulus 0.0054 0.039 0.0818
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0894 0.4282
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0461 0.4287 0.5756
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0217 0.0204
Leishmania major DNA polymerase eta, putative 0.0044 0.0299 0.0362
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0115 0.0268
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0461 0.4287 0.4285
Onchocerca volvulus Cathepsin L homolog 0.0073 0.0571 0.1208
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Leishmania major receptor-type adenylate cyclase a-like protein 0.0203 0.1819 0.2418
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0894 0.4282
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0503 0.469 0.6302
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0323 0.0662
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0571 0.0594
Schistosoma mansoni cpg binding protein 0.006 0.045 0.0438
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0059 0.0136
Echinococcus multilocularis thyroid hormone receptor alpha 0.0134 0.1159 0.1148
Loa Loa (eye worm) hypothetical protein 0.0054 0.039 0.0402
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0115 0.0339
Schistosoma mansoni neuronal calcium sensor 0.0054 0.039 0.0378
Loa Loa (eye worm) hypothetical protein 0.0254 0.2302 0.2422
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0789 0.7423 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0377 0.3484 0.4671
Schistosoma mansoni hypothetical protein 0.0406 0.3755 0.3752
Onchocerca volvulus 0.0036 0.0217 0.0446
Echinococcus multilocularis programmed cell death protein 0.0062 0.0466 0.0454
Trypanosoma brucei kinesin, putative 0.025 0.2265 0.3049
Loa Loa (eye worm) hypothetical protein 0.0027 0.0131 0.0129
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0254 0.2302 0.7348
Entamoeba histolytica cysteine proteinase, putative 0.0232 0.2092 0.6626
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0761 0.7151 0.9632
Schistosoma mansoni neuronal calcium sensor 0.0054 0.039 0.0378
Loa Loa (eye worm) hypothetical protein 0.0461 0.4287 0.4519
Loa Loa (eye worm) hypothetical protein 0.0108 0.0914 0.0956
Loa Loa (eye worm) hypothetical protein 0.0073 0.0571 0.0594
Echinococcus granulosus lamin 0.0027 0.0131 0.0119
Brugia malayi Uncoordinated protein 44 0.0014 0.0013 0.0004
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0056 1
Echinococcus multilocularis calmodulin 0.0054 0.039 0.0377
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0297 0.2714 0.3629
Brugia malayi Cathepsin L-like precursor 0.0108 0.0914 0.0956
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0056 0.0032
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0014 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Toxoplasma gondii troponin c, isotype gamma, putative 0.0054 0.039 0.122
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0056 0.1292
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0059 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0571 0.1825
Brugia malayi fibroinase precursor 0.0073 0.0571 0.0594
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0571 0.0594
Loa Loa (eye worm) hypothetical protein 0.034 0.3129 0.3296
Giardia lamblia Cathepsin B precursor 0.0073 0.0571 0.3194
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0181 0.1608 0.1599
Plasmodium falciparum serine repeat antigen 7 0.0073 0.0571 0.1741
Schistosoma mansoni cpg binding protein 0.006 0.045 0.0438
Onchocerca volvulus 0.0073 0.0571 0.1208
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0059 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0297 0.2714 0.3654
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0073 0.0571 0.1741
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0055 0.0403 0.0502
Echinococcus multilocularis lamin dm0 0.0027 0.0131 0.0119
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0217 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0217 0.0918
Giardia lamblia Hypothetical protein 0.0055 0.0403 0.2199
Echinococcus multilocularis geminin 0.0167 0.1474 0.1463
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0056 0.0043
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0032 0.0101
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0073 0.0571 0.1193
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0056 0.0043
Trypanosoma brucei Component of motile flagella 41 0.0054 0.039 0.0521
Giardia lamblia Cathepsin L precursor 0.0073 0.0571 0.3194
Schistosoma mansoni cathepsin B (C01 family) 0.0073 0.0571 0.056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Toxoplasma gondii exonuclease III APE 0.0019 0.0056 0.0149
Echinococcus granulosus cathepsin L 0.0073 0.0571 0.0559
Trypanosoma cruzi major cysteine proteinase, putative 0.0119 0.1015 0.133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0571 0.1825
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0571 0.056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.3129 1
Entamoeba histolytica cysteine protease, putative 0.0073 0.0571 0.1677
Leishmania major cathepsin L-like protease 0.034 0.3129 0.419
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0193 0.172 0.1712
Loa Loa (eye worm) hypothetical protein 0.0754 0.7086 0.7477
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0789 0.7423 1
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0054 0.039 0.0521
Trypanosoma brucei small myristoylated protein 1-2 0.035 0.3226 0.4344
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0054 0.039 0.0377
Trypanosoma brucei unspecified product 0.0203 0.1819 0.2447
Brugia malayi Pre-SET motif family protein 0.0206 0.1851 0.1946
Trypanosoma brucei Calpain-like protein 1.1 0.0789 0.7423 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0761 0.7151 0.9631
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0457 0.4243 0.5697
Giardia lamblia Cathepsin B precursor 0.0073 0.0571 0.3194
Entamoeba histolytica calpain family cysteine protease, putative 0.0254 0.2302 0.7308
Leishmania major cathepsin L-like protease 0.034 0.3129 0.419
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0054 0.039 0.1245
Trypanosoma brucei antigen, putative 0.0503 0.469 0.6316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0387 0.3572 0.481
Trypanosoma brucei trypanothione reductase 0.0047 0.0323 0.0432
Brugia malayi Kringle domain containing protein 0.0021 0.0081 0.0076
Brugia malayi hypothetical protein 0.012 0.1025 0.1073
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0789 0.7423 1
Trichomonas vaginalis calmodulin, putative 0.0054 0.039 0.1245
Leishmania major protein kinase, putative 0.0054 0.039 0.0484
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0019
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0073 0.0571 0.1193
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0013 0.000000019692
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0032 0.0039
Leishmania major small myristoylated protein-3, putative 0.0297 0.2714 0.3629
Brugia malayi Papain family cysteine protease containing protein 0.034 0.3129 0.3296
Toxoplasma gondii hypothetical protein 0.0254 0.2302 0.7348
Entamoeba histolytica cysteine protease, putative 0.0181 0.1608 0.5051
Trypanosoma cruzi cysteine peptidase, putative 0.0387 0.3572 0.479
Leishmania major cathepsin L-like protease 0.034 0.3129 0.419
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0054 0.039 0.1087
Trichomonas vaginalis calmodulin, putative 0.0054 0.039 0.1245
Schistosoma mansoni centrin-related 0.0054 0.039 0.0378
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.3129 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0073 0.0571 0.0594
Onchocerca volvulus 0.0054 0.039 0.0818
Brugia malayi beta-lactamase family protein 0.0036 0.0217 0.0219
Trypanosoma cruzi small myristoylated protein 1-1 0.035 0.3226 0.4322
Brugia malayi hypothetical protein 0.0016 0.0031 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0059 0.0037
Leishmania major cathepsin L-like protease 0.034 0.3129 0.419
Toxoplasma gondii histone lysine methyltransferase SET1 0.0108 0.0913 0.2899
Brugia malayi Cathepsin L-like cysteine proteinase 0.0232 0.2092 0.2201
Brugia malayi cathepsin F-like cysteine proteinase 0.0073 0.0571 0.0594
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0571 0.1825

Activities

Activity type Activity value Assay description Source Reference
D (functional) = 12 % Percent of differentiated HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at a concentration of 2.0 mM ChEMBL. 3806621
D (functional) = 12 % Percent of differentiated HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at a concentration of 2.0 mM ChEMBL. 3806621
D (functional) = 13 % Percent of differentiated HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at a concentration of 1.5 mM ChEMBL. 3806621
D (functional) = 13 % Percent of differentiated HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at a concentration of 1.5 mM ChEMBL. 3806621
D (functional) = 24 % Percent of differentiated HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at a concentration of 1.0 mM ChEMBL. 3806621
D (functional) = 24 % Percent of differentiated HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at a concentration of 1.0 mM ChEMBL. 3806621
Total cells (functional) = 0.00007 ml Differentiation studies was conducted with the HL-60 human myeloid leukemia cell line and total cells were counted with a Coulter counter, at a concentration of 1.0 mM ChEMBL. 3806621
Total cells (functional) = 0.00007 ml Differentiation studies was conducted with the HL-60 human myeloid leukemia cell line and total cells were counted with a Coulter counter, at a concentration of 1.0 mM ChEMBL. 3806621
Total cells (functional) = 0.000094 ml Differentiation studies was conducted with the HL-60 human myeloid leukemia cell line and Total cells were counted with a Coulter counter, at a concentration of 2.0 mM (number of experiments = 1) ChEMBL. 3806621
Total cells (functional) = 0.000094 ml Differentiation studies was conducted with the HL-60 human myeloid leukemia cell line and Total cells were counted with a Coulter counter, at a concentration of 2.0 mM (number of experiments = 1) ChEMBL. 3806621
Total cells (functional) = 0.000107 ml Differentiation studies was conducted with the HL-60 human myeloid leukemia cell line and Total cells were counted with a Coulter counter, at a concentration of 1.5 mM ChEMBL. 3806621
Total cells (functional) = 0.000107 ml Differentiation studies was conducted with the HL-60 human myeloid leukemia cell line and Total cells were counted with a Coulter counter, at a concentration of 1.5 mM ChEMBL. 3806621
V (functional) = 78 % Percent of viability for HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at concentration of 1.5 mM ChEMBL. 3806621
V (functional) = 78 % Percent of viability for HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at concentration of 1.5 mM ChEMBL. 3806621
V (functional) = 82 % Percent of viability for HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at concentration of 2.0 mM ChEMBL. 3806621
V (functional) = 82 % Percent of viability for HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at concentration of 2.0 mM ChEMBL. 3806621
V (functional) = 85 % Percent of viability for HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at concentration of 1.0 mM ChEMBL. 3806621
V (functional) = 85 % Percent of viability for HL-60 cells was determined by dividing number of viable differentiated cells by total number of viable cells, at concentration of 1.0 mM ChEMBL. 3806621

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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