Detailed information for compound 281286

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 614.809 | Formula: C36H54O8
  • H donors: 1 H acceptors: 2 LogP: 7.31 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: Cc1cc(cc2c1OCCOCCOCc1cc(cc(COCCOCCO2)c1C(=O)O)C(C)(C)C)C(CC(C)(C)C)(C)C
  • InChi: 1S/C36H54O8/c1-25-18-29(36(8,9)24-34(2,3)4)21-30-32(25)44-17-15-40-11-13-42-23-27-20-28(35(5,6)7)19-26(31(27)33(37)38)22-41-12-10-39-14-16-43-30/h18-21H,10-17,22-24H2,1-9H3,(H,37,38)
  • InChiKey: RPGAWOPBDGTDLP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cysteine protease 0.014 0.1197 0.1189
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0073 0.0481 0.1456
Entamoeba histolytica calmodulin, putative 0.0042 0.0153 0.1018
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0154 0.134 0.1332
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0049 0.0229 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0229 0.0678
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Trichomonas vaginalis calmodulin, putative 0.0043 0.0163 0.0476
Brugia malayi Trypsin family protein 0.0073 0.0488 0.0488
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0049 0.0229 0.0722
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.01 0.01
Brugia malayi Metabotropic glutamate receptor precursor. 0.0052 0.0261 0.0261
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Brugia malayi cathepsin F-like cysteine proteinase 0.0049 0.0229 0.0229
Trypanosoma brucei calpain-like protein, putative 0.0242 0.228 0.7005
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.01 0.0091
Trypanosoma cruzi kinesin, putative 0.0169 0.1507 0.1499
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0229 0.0229
Brugia malayi calpain family protein 1 0.0641 0.6527 0.6527
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.014 0.1197 0.3664
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0079 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0154 0.134 0.1332
Entamoeba histolytica cysteine proteinase, putative 0.014 0.1197 0.7942
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0049 0.0229 0.0229
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.2273
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0049 0.0229 0.068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0042 0.0153 0.0446
Mycobacterium tuberculosis Conserved protein 0.0035 0.0079 0.032
Trypanosoma cruzi calmodulin, putative 0.0042 0.0153 0.0145
Echinococcus granulosus calpain A 0.0684 0.6982 0.698
Loa Loa (eye worm) calmodulin-like protein 0.0042 0.0153 0.0153
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0804 0.5338
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0079 0.007
Entamoeba histolytica hypothetical protein, conserved 0.0043 0.0163 0.1083
Onchocerca volvulus 0.0103 0.0804 0.2034
Loa Loa (eye worm) hypothetical protein 0.0073 0.0481 0.0481
Brugia malayi calcium-binding protein 0.0042 0.0153 0.0153
Plasmodium vivax calpain, putative 0.0242 0.228 1
Echinococcus multilocularis tyrosine kinase 0.0052 0.0261 0.0252
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0968 1 1
Plasmodium vivax unspecified product 0.0037 0.01 0.0095
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0052 0.0261 0.0252
Trichomonas vaginalis esterase, putative 0.0035 0.0079 0.0217
Toxoplasma gondii cathepsin B 0.0333 0.3251 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0049 0.0229 0.0722
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0042 0.0153 0.0145
Echinococcus granulosus cathepsin l1 0.014 0.1197 0.1189
Echinococcus granulosus cathepsin L 0.0049 0.0229 0.022
Toxoplasma gondii EF hand domain-containing protein 0.0042 0.0153 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0153 0.0446
Giardia lamblia Cathepsin B precursor 0.0049 0.0229 0.0212
Entamoeba histolytica cysteine proteinase 2 0.0086 0.0621 0.4123
Plasmodium vivax serine-repeat antigen (SERA) 0.0049 0.0229 0.068
Chlamydia trachomatis glutamine binding protein 0.026 0.2473 0.5
Toxoplasma gondii centrin, putative 0.0042 0.0153 0.0234
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0101 0.0787 0.0778
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0052 0.0261 0.0252
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Brugia malayi Papain family cysteine protease containing protein 0.0086 0.0621 0.0621
Echinococcus multilocularis neurocalcin 0.0042 0.0153 0.0145
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Schistosoma mansoni glutamate receptor kainate 0.0101 0.0787 0.0778
Schistosoma mansoni tyrosine kinase 0.0052 0.0261 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0229 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.0621 0.1889
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0229 0.0229
Echinococcus multilocularis cathepsin l cysteine peptidase 0.014 0.1197 0.1189
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0079 0.007
Entamoeba histolytica cysteine protease, putative 0.0049 0.0229 0.1518
Loa Loa (eye worm) trypsin family protein 0.0073 0.0488 0.0488
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0049 0.0229 0.068
Plasmodium falciparum serine repeat antigen 2 0.0049 0.0229 0.0722
Loa Loa (eye worm) hypothetical protein 0.0058 0.0323 0.0323
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Giardia lamblia Cathepsin B precursor 0.0049 0.0229 0.0212
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.014 0.1197 0.1189
Echinococcus granulosus atrial natriuretic peptide receptor 0.0052 0.0261 0.0252
Schistosoma mansoni neuronal calcium sensor 0.0042 0.0153 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0037 0.01 0.01
Schistosoma mansoni cathepsin F (C01 family) 0.014 0.1197 0.1189
Schistosoma mansoni glutamate receptor kainate 0.0101 0.0787 0.0778
Brugia malayi Cathepsin L-like precursor 0.0037 0.01 0.01
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0049 0.0229 0.068
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Echinococcus multilocularis cathepsin l cysteine peptidase 0.014 0.1197 0.1189
Trichomonas vaginalis centrin, putative 0.0042 0.0153 0.0446
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Trichomonas vaginalis calcium binding protein, putative 0.0042 0.0153 0.0446
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0252 0.2383 0.2383
Plasmodium vivax unspecified product 0.0086 0.0621 0.2463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0481 0.1456
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1456
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0049 0.0229 0.1518
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0079 0.007
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0042 0.0153 0.0145
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0073 0.0488 0.0488
Entamoeba histolytica calcium-binding protein, putative 0.0042 0.0153 0.1018
Giardia lamblia Cathepsin B precursor 0.0049 0.0229 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.0621 0.0613
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0073 0.0481 0.0472
Echinococcus multilocularis enteropeptidase 0.0073 0.0488 0.048
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0079 0.0217
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.014 0.1197 0.3664
Schistosoma mansoni reticulocalbin 0.0042 0.0153 0.0145
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0049 0.0229 0.068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0229 0.0678
Onchocerca volvulus 0.0073 0.0488 0.1234
Onchocerca volvulus 0.014 0.1197 0.3026
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0481 0.0472
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0052 0.0261 0.0261
Plasmodium vivax vivapain-3 0.0086 0.0621 0.2463
Schistosoma mansoni calpain (C02 family) 0.0242 0.228 0.2273
Echinococcus granulosus glutamate receptor subunit protein glur 0.0101 0.0787 0.0778
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0073 0.0481 0.1456
Giardia lamblia Cathepsin L-like protease 0.0049 0.0229 0.0212
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0128 0.0128
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0323 0.0323
Brugia malayi cathepsin Z-like cysteine proteinase 0.0049 0.0229 0.0229
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0079 0.032
Trypanosoma brucei I/6 autoantigen 0.0042 0.0153 0.0446
Schistosoma mansoni cathepsin B (C01 family) 0.0049 0.0229 0.022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Brugia malayi Cathepsin L-like cysteine proteinase 0.0103 0.0804 0.0804
Giardia lamblia Cathepsin B precursor 0.0049 0.0229 0.0212
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.018 0.0171
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0086 0.0621 0.0613
Echinococcus multilocularis hypothetical protein 0.0242 0.228 0.2273
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Trypanosoma cruzi calmodulin, putative 0.0042 0.0153 0.0145
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0052 0.0261 0.0252
Schistosoma mansoni cathepsin s 0.0037 0.01 0.0091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0042 0.0153 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Echinococcus multilocularis neuronal calcium sensor 0.0042 0.0153 0.0145
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0079 0.007
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0229 0.022
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0043 0.0163 0.0155
Brugia malayi Trypsin family protein 0.0073 0.0488 0.0488
Schistosoma mansoni hypothetical protein 0.0042 0.0153 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0621 0.1889
Mycobacterium ulcerans beta-lactamase 0.0035 0.0079 0.032
Echinococcus granulosus EF hand domain containing family member A2 0.0042 0.0153 0.0145
Brugia malayi beta-lactamase family protein 0.0035 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0049 0.0229 0.1518
Schistosoma mansoni hypothetical protein 0.004 0.0128 0.0119
Entamoeba histolytica cysteine protease, putative 0.0049 0.0229 0.1518
Schistosoma mansoni hypothetical protein 0.0101 0.0787 0.0778
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0229 0.022
Leishmania major centrin, putative,caltractin, putative 0.0042 0.0153 0.0472
Brugia malayi hypothetical protein 0.0052 0.0261 0.0261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0804 0.2454
Loa Loa (eye worm) hypothetical protein 0.0103 0.0804 0.0804
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Echinococcus granulosus nmda type glutamate receptor 0.0362 0.3552 0.3547
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0073 0.0488 0.0488
Trypanosoma cruzi I/6 autoantigen, putative 0.0042 0.0153 0.0145
Brugia malayi cathepsin L-like cysteine proteinase 0.0049 0.0229 0.0229
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0323 0.0323
Echinococcus multilocularis calpain A 0.0684 0.6982 0.698
Brugia malayi fibroinase precursor 0.0049 0.0229 0.0229
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0481 0.1456
Brugia malayi Trypsin family protein 0.0073 0.0488 0.0488
Schistosoma mansoni cathepsin F (C01 family) 0.014 0.1197 0.1189
Brugia malayi cathepsin Z-like cysteine proteinase 0.0049 0.0229 0.0229
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0242 0.228 0.7005
Toxoplasma gondii EFHC1, putative 0.0042 0.0153 0.0234
Brugia malayi programmed cell death protein 6 0.0042 0.0153 0.0153
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0073 0.0488 0.048
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0163 0.0382
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0073 0.0488 0.048
Loa Loa (eye worm) hypothetical protein 0.0968 1 1
Leishmania major calmodulin, putative 0.0042 0.0153 0.0472
Leishmania major extracellular receptor, putative 0.0052 0.0261 0.0802
Echinococcus granulosus glutamate receptor 2 0.0154 0.134 0.1332
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0481 0.1456
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.018 0.0171
Giardia lamblia Cathepsin L precursor 0.0049 0.0229 0.0212
Plasmodium falciparum serine repeat antigen 8 0.0049 0.0229 0.0722
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.026 0.2473 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0481 0.1456
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0481 0.0472
Loa Loa (eye worm) cathepsin B 0.0333 0.3251 0.3251
Mycobacterium ulcerans hypothetical protein 0.0035 0.0079 0.032
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Leishmania major kinesin, putative 0.0169 0.1507 0.4634
Leishmania major hypothetical protein, conserved 0.0073 0.0481 0.1479
Loa Loa (eye worm) hypothetical protein 0.0049 0.0229 0.0229
Plasmodium vivax unspecified product 0.0049 0.0229 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0229 0.0678
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0101 0.0787 0.0778
Brugia malayi Bromodomain containing protein 0.0044 0.018 0.018
Echinococcus multilocularis transmembrane protease serine 3 0.0073 0.0488 0.048
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0641 0.6527 0.6524
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0229 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Echinococcus multilocularis calpain family protein 1, d 0.0472 0.4728 0.4723
Loa Loa (eye worm) hypothetical protein 0.0037 0.01 0.01
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0242 0.228 0.2273
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0042 0.0153 0.0446
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0804 0.2454
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0042 0.0153 0.0145
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0229 0.0212
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0229 0.022
Leishmania major calmodulin-like protein 0.0042 0.0153 0.0472
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0049 0.0229 0.022
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Giardia lamblia Encystation-specific protease 0.0049 0.0229 0.0212
Trichomonas vaginalis hypothetical protein 0.0073 0.0481 0.1456
Schistosoma mansoni centrin-related 0.0042 0.0153 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0153 0.0446
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0242 0.228 0.2273
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Echinococcus granulosus glycoprotein Antigen 5 0.0073 0.0488 0.048
Loa Loa (eye worm) hypothetical protein 0.0073 0.0488 0.0488
Brugia malayi calpain 7 0.0242 0.228 0.228
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Echinococcus granulosus EF HAND 1 calcium binding site 0.0042 0.0153 0.0145
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0101 0.0787 0.0778
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0079 0.032
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Leishmania major protein kinase, putative 0.0042 0.0153 0.0472
Loa Loa (eye worm) hypothetical protein 0.0082 0.058 0.058
Echinococcus granulosus cathepsin L 0.0086 0.0621 0.0613
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0101 0.0787 0.0778
Loa Loa (eye worm) hypothetical protein 0.0073 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0049 0.0229 0.0229
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0042 0.0153 0.0145
Echinococcus granulosus calpain 0.0242 0.228 0.2273
Echinococcus multilocularis programmed cell death protein 0.0042 0.0153 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Onchocerca volvulus 0.0073 0.0488 0.1234
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0073 0.0488 0.048
Echinococcus granulosus glutamate NMDA receptor subunit 0.0101 0.0787 0.0778
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0049 0.0229 0.0722
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Mycobacterium ulcerans lipase LipD 0.0035 0.0079 0.032
Mycobacterium ulcerans hypothetical protein 0.0073 0.0488 0.1972
Echinococcus multilocularis NMDA receptor 0.0101 0.0787 0.0778
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0073 0.0481 0.1267
Trypanosoma brucei calpain-like protein, putative 0.0242 0.228 0.7005
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0049 0.0229 0.022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0151 0.0142
Schistosoma mansoni cathepsin F (C01 family) 0.0103 0.0804 0.0796
Trypanosoma brucei calpain-like protein, putative 0.0242 0.228 0.7005
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0621 0.1889
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0444 0.0436
Echinococcus granulosus cathepsin b 0.0968 1 1
Schistosoma mansoni glutamate receptor NMDA 0.0101 0.0787 0.0778
Mycobacterium tuberculosis Conserved protein 0.0035 0.0079 0.032
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.026 0.2473 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.01 0.01
Echinococcus granulosus Mastin 0.0073 0.0488 0.048
Loa Loa (eye worm) hypothetical protein 0.004 0.0128 0.0128
Trypanosoma brucei Calpain-like protein CALP1.3 0.0073 0.0481 0.1456
Loa Loa (eye worm) hypothetical protein 0.0641 0.6527 0.6527
Giardia lamblia Cathepsin B precursor 0.0333 0.3251 1
Loa Loa (eye worm) programmed cell death protein 6 0.0043 0.0163 0.0163
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0079 0.032
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0079 0.032
Echinococcus multilocularis calmodulin 0.0042 0.0153 0.0145
Giardia lamblia Cysteine protease 0.0049 0.0229 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Loa Loa (eye worm) hypothetical protein 0.0569 0.5753 0.5753
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Echinococcus multilocularis calpain 5 0.0242 0.228 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Echinococcus multilocularis glutamate receptor 2 0.0101 0.0787 0.0778
Echinococcus granulosus metabotropic glutamate receptor 5 0.0052 0.0261 0.0252
Trypanosoma brucei calpain, putative 0.0073 0.0481 0.1456
Brugia malayi Cathepsin L-like precursor 0.014 0.1197 0.1197
Loa Loa (eye worm) hypothetical protein 0.0049 0.0234 0.0234
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0683 0.6973 0.697
Echinococcus granulosus neuronal calcium sensor 0.0042 0.0153 0.0145
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0079 0.032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Leishmania major programmed cell death 6 protein-like protein 0.0042 0.0153 0.0472
Entamoeba histolytica hypothetical protein 0.0049 0.0229 0.1518
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.026 0.2473 1
Loa Loa (eye worm) EF hand family protein 0.0042 0.0153 0.0153
Trypanosoma brucei Component of motile flagella 41 0.0042 0.0153 0.0446
Echinococcus multilocularis EF hand domain containing family member A2 0.0043 0.0163 0.0155
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Giardia lamblia Cathepsin L precursor 0.0049 0.0229 0.0212
Loa Loa (eye worm) hypothetical protein 0.0049 0.0229 0.0229
Giardia lamblia Cathepsin L precursor 0.0049 0.0229 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0229 0.0212
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0079 0.0217
Trichomonas vaginalis centrin, putative 0.0042 0.0153 0.0446
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0079 0.032
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0073 0.0488 0.0488
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.018 0.018
Onchocerca volvulus 0.014 0.1197 0.3026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.2273
Loa Loa (eye worm) calpain 5 0.0169 0.1507 0.1507
Schistosoma mansoni metabotropic glutamate receptor 0.0052 0.0261 0.0252
Brugia malayi Guanylyl cyclase protein 23 0.0052 0.0261 0.0261
Onchocerca volvulus Cathepsin L homolog 0.014 0.1197 0.3026
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0154 0.134 0.1332
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0229 0.0678
Echinococcus multilocularis glutamate receptor 2 0.0052 0.0261 0.0252
Brugia malayi beta-lactamase family protein 0.0035 0.0079 0.0079
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.014 0.1197 0.1197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Echinococcus granulosus calcium uptake protein 1 0.0043 0.0163 0.0155
Echinococcus granulosus cathepsin b 0.0968 1 1
Toxoplasma gondii calcium-dependent protein kinase 0.0043 0.0163 0.0265
Brugia malayi calpain 5 0.0073 0.0481 0.0481
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0049 0.0229 0.022
Onchocerca volvulus 0.0073 0.0488 0.1234
Trichomonas vaginalis calpain, putative 0.0073 0.0481 0.1456
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Trichomonas vaginalis calpain, putative 0.0073 0.0481 0.1456
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0229 0.0229
Echinococcus granulosus calpain 7 C02 family 0.0242 0.228 0.2273
Giardia lamblia Cathepsin B precursor 0.0333 0.3251 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Schistosoma mansoni calpain-7 (C02 family) 0.0242 0.228 0.2273
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.018 0.0171
Trypanosoma cruzi centrin, putative 0.0042 0.0153 0.0145
Toxoplasma gondii hypothetical protein 0.0073 0.0481 0.1267
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0153 0.0446
Schistosoma mansoni ef hand domain family member A2 0.0042 0.0153 0.0145
Brugia malayi Glutamate receptor 2 precursor 0.0101 0.0787 0.0787
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0229 0.0678
Mycobacterium leprae Probable lipase LipE 0.0035 0.0079 1
Schistosoma mansoni rab 0.0042 0.0153 0.0145
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0042 0.0153 0.0145
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0481 0.1456
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Loa Loa (eye worm) hypothetical protein 0.0103 0.0804 0.0804
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0683 0.6973 0.697
Plasmodium vivax vivapain-2 0.014 0.1197 0.5078
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0079 0.007
Plasmodium falciparum cysteine proteinase falcipain 2a 0.014 0.1197 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0229 0.0678
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0154 0.134 0.1332
Loa Loa (eye worm) calpain family protein 1 0.0641 0.6527 0.6527
Echinococcus granulosus enteropeptidase 0.0073 0.0488 0.048
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Onchocerca volvulus Cathepsin F homolog 0.014 0.1197 0.3026
Trypanosoma cruzi I/6 autoantigen, putative 0.0042 0.0153 0.0145
Loa Loa (eye worm) cysteine protease 0.014 0.1197 0.1197
Schistosoma mansoni calmodulin 0.0042 0.0153 0.0145
Echinococcus granulosus EF hand domain containing family member A2 0.0043 0.0163 0.0155
Echinococcus multilocularis Mastin 0.0073 0.0488 0.048
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0042 0.0153 0.1018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0242 0.228 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0333 0.3251 1
Entamoeba histolytica grainin, putative 0.0043 0.0163 0.1083
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0333 0.3251 0.3245
Toxoplasma gondii cathepsin CPL 0.014 0.1197 0.3523
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Trichomonas vaginalis myosin light chain 1, putative 0.0042 0.0153 0.0446
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0049 0.0229 0.068
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Schistosoma mansoni hypothetical protein 0.0073 0.0481 0.0472
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Loa Loa (eye worm) hypothetical protein 0.0073 0.0488 0.0488
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0101 0.0787 0.0778
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0481 0.1456
Leishmania major calmodulin, putative 0.0042 0.0153 0.0472
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0049 0.0229 0.0229
Entamoeba histolytica calcium binding family protein 0.0042 0.0153 0.1018
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0481 0.1456
Onchocerca volvulus 0.0052 0.0261 0.0659
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0049 0.0229 0.068
Trypanosoma cruzi cysteine proteinase, putative 0.0086 0.0621 0.0613
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Schistosoma mansoni Mername-AA248 (C02 family) 0.0242 0.228 0.2273
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0229 0.022
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Echinococcus granulosus receptor type guanylyl cyclase 0.0052 0.0261 0.0252
Giardia lamblia Cysteine protease 0.0049 0.0229 0.0212
Plasmodium vivax vivapain-2 0.014 0.1197 0.5078
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Brugia malayi Cathepsin L-like precursor 0.014 0.1197 0.1197
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0444 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Trypanosoma brucei hypothetical protein 0.0073 0.0481 0.1456
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Loa Loa (eye worm) hypothetical protein 0.0037 0.01 0.01
Echinococcus multilocularis programmed cell death protein 0.0042 0.0153 0.0145
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.1181 0.1181
Loa Loa (eye worm) hypothetical protein 0.0244 0.2299 0.2299
Loa Loa (eye worm) fibroinase 0.014 0.1197 0.1197
Echinococcus multilocularis cathepsin L 0.0049 0.0229 0.022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Echinococcus multilocularis calmodulin 0.0042 0.0153 0.0145
Trypanosoma brucei caltractin, putative 0.0042 0.0153 0.0446
Loa Loa (eye worm) glutamate receptor 2 0.0101 0.0787 0.0787
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0362 0.3552 0.3547
Echinococcus granulosus cysteine protease 0.0086 0.0621 0.0613
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.0621 0.4123
Leishmania major centrin, putative 0.0042 0.0153 0.0472
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0323 0.0323
Leishmania major centrin, putative 0.0042 0.0153 0.0472
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0049 0.0229 0.0678
Echinococcus multilocularis calbindin 32 0.0043 0.0163 0.0155
Onchocerca volvulus 0.014 0.1197 0.3026
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Schistosoma mansoni calpain-7 (C02 family) 0.0242 0.228 0.2273
Brugia malayi Glutamate receptor 1 precursor 0.0101 0.0787 0.0787
Echinococcus multilocularis cathepsin b 0.0968 1 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0079 0.007
Loa Loa (eye worm) ctsf protein 0.014 0.1197 0.1197
Echinococcus multilocularis calumenin 0.0043 0.0163 0.0155
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0042 0.0153 0.0338
Brugia malayi cathepsin L precursor 0.0049 0.0229 0.0229
Echinococcus granulosus tyrosine kinase 0.0052 0.0261 0.0252
Echinococcus granulosus neurocalcin 0.0042 0.0153 0.0145
Trypanosoma cruzi extracellular receptor, putative 0.0052 0.0261 0.0252
Trypanosoma brucei centrin, putative 0.0042 0.0153 0.0446
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0151 0.0142
Echinococcus granulosus microtubule associated protein 2 0.0801 0.8222 0.8221
Echinococcus granulosus cathepsin l1 0.0103 0.0804 0.0796
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0154 0.134 0.1332
Loa Loa (eye worm) hypothetical protein 0.0049 0.0229 0.0229
Schistosoma mansoni neuronal calcium sensor 0.0042 0.0153 0.0145
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Schistosoma mansoni hypothetical protein 0.0042 0.0153 0.0145
Toxoplasma gondii troponin c, isotype gamma, putative 0.0042 0.0153 0.0234
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Loa Loa (eye worm) hypothetical protein 0.0045 0.0181 0.0181
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0481 0.0472
Trypanosoma brucei cysteine peptidase C (CPC) 0.0333 0.3251 1
Leishmania major cysteine peptidase A (CPA) 0.014 0.1197 0.3681
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.2273
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0481 0.0472
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.7013
Trichomonas vaginalis calcineurin B subunit, putative 0.0043 0.0163 0.0476
Toxoplasma gondii calmodulin CAM1 0.0043 0.0163 0.0265
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Giardia lamblia Cysteine protease 0.0049 0.0229 0.0212
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0042 0.0153 0.0446
Plasmodium vivax serine-repeat antigen (SERA) 0.0049 0.0229 0.068
Loa Loa (eye worm) hypothetical protein 0.0073 0.0488 0.0488
Trypanosoma cruzi centrin, putative 0.0042 0.0153 0.0145
Leishmania major hypothetical protein, conserved 0.0043 0.0163 0.0502
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Entamoeba histolytica grainin 2 0.0042 0.0153 0.1018
Echinococcus multilocularis glutamate receptor 2 0.0154 0.134 0.1332
Brugia malayi Cathepsin L-like precursor 0.014 0.1197 0.1197
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0052 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.0073 0.0488 0.048
Plasmodium falciparum serine repeat antigen 1 0.0049 0.0229 0.0722
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.2081 0.8415
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0042 0.0153 0.0145
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Brugia malayi Papain family cysteine protease containing protein 0.014 0.1197 0.1197
Brugia malayi Trypsin-like protease protein 5 0.0073 0.0488 0.0488
Brugia malayi calpain 5 0.0169 0.1507 0.1507
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Trypanosoma cruzi caltractin, putative 0.0042 0.0153 0.0145
Onchocerca volvulus 0.0035 0.0079 0.02
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Loa Loa (eye worm) glutamate receptor 0.0052 0.0261 0.0261
Brugia malayi Cathepsin L-like precursor 0.0103 0.0804 0.0804
Loa Loa (eye worm) calpain family protein 1 0.0472 0.4728 0.4728
Giardia lamblia Hypothetical protein 0.0049 0.0229 0.0212
Onchocerca volvulus 0.0049 0.0229 0.0578
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0261 0.0261
Echinococcus multilocularis calpain 0.0242 0.228 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0229 0.0678
Entamoeba histolytica cysteine protease, putative 0.014 0.1197 0.7942
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Loa Loa (eye worm) hypothetical protein 0.0103 0.0804 0.0804
Plasmodium falciparum serine repeat antigen 6 0.0049 0.0229 0.0722
Plasmodium vivax centrin-1, putative 0.0042 0.0153 0.0338
Trypanosoma brucei calpain, putative 0.0073 0.0481 0.1456
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0049 0.0229 0.068
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0968 1 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0079 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0229 0.0678
Onchocerca volvulus 0.0052 0.0261 0.0659
Trichomonas vaginalis calmodulin-2, putative 0.0042 0.0153 0.0446
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1456
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0333 0.3251 1
Echinococcus granulosus calpain A 0.0242 0.228 0.2273
Giardia lamblia Hypothetical protein 0.0049 0.0229 0.0212
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0481 0.0472
Leishmania major hypothetical protein, conserved 0.0042 0.0153 0.0472
Entamoeba histolytica cysteine protease, putative 0.0049 0.0229 0.1518
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0261 0.0261
Schistosoma mansoni mitochondrial solute carrier 0.0042 0.0153 0.0145
Onchocerca volvulus 0.0043 0.0163 0.0413
Brugia malayi EF hand family protein 0.0043 0.0163 0.0163
Brugia malayi Calmodulin-like protein 0.0042 0.0153 0.0153
Schistosoma mansoni hypothetical protein 0.0073 0.0488 0.048
Echinococcus granulosus transmembrane protease serine 3 0.0073 0.0488 0.048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Trypanosoma brucei mitochondrial calcium uptake 1 0.0042 0.0153 0.0446
Echinococcus granulosus calmodulin 0.0042 0.0153 0.0145
Toxoplasma gondii cathepsin CPC2 0.0049 0.0229 0.0472
Loa Loa (eye worm) calpain 0.0242 0.228 0.228
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0968 1 1
Echinococcus multilocularis nmda type glutamate receptor 0.0052 0.0261 0.0252
Entamoeba histolytica cysteine proteinase 1, putative 0.0086 0.0621 0.4123
Schistosoma mansoni glutamate receptor kainate 0.0101 0.0787 0.0778
Trichomonas vaginalis calcium binding protein, putative 0.0042 0.0153 0.0446
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0043 0.0163 0.0155
Brugia malayi Cathepsin L-like precursor 0.0103 0.0804 0.0804
Echinococcus multilocularis cathepsin L 0.0086 0.0621 0.0613
Leishmania major calpain protease-like protein 0.0073 0.0481 0.1479
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.0621 0.1889
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0229 0.0229
Brugia malayi Cathepsin L-like precursor 0.014 0.1197 0.1197
Schistosoma mansoni ATP-binding cassette transporter 0.0101 0.0787 0.0778
Schistosoma mansoni centrin 0.0042 0.0153 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Schistosoma mansoni reticulocalbin 0.0043 0.0163 0.0155
Trypanosoma brucei Calpain-like protein 1.2 0.0073 0.0481 0.1456
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Giardia lamblia Cathepsin L precursor 0.0049 0.0229 0.0212
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0079 0.0217
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0052 0.0261 0.0659
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.1181 0.1181
Giardia lamblia Cysteine protease 0.0049 0.0229 0.0212
Leishmania major hypothetical protein, conserved 0.0035 0.0079 0.0243
Echinococcus granulosus programmed cell death protein 0.0042 0.0153 0.0145
Brugia malayi Bromodomain containing protein 0.0087 0.0633 0.0633
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.0621 0.4123
Loa Loa (eye worm) papain family cysteine protease containing protein 0.014 0.1197 0.1197
Echinococcus granulosus cathepsin l cysteine peptidase 0.014 0.1197 0.1189
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0042 0.0153 0.0145
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0079 0.032
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0229 0.022
Trypanosoma brucei calpain-like protein, putative 0.0242 0.228 0.7005
Trypanosoma cruzi cruzipain precursor, putative 0.014 0.1197 0.1189
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Toxoplasma gondii preprocathepsin c precursor, putative 0.0049 0.0229 0.0472
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0103 0.0804 0.0796
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Schistosoma mansoni metabotropic glutamate receptor 0.0052 0.0261 0.0252
Schistosoma mansoni glutamate receptor NMDA 0.0154 0.134 0.1332
Toxoplasma gondii centrin 0.0042 0.0153 0.0234
Giardia lamblia Cathepsin L-like protease 0.0049 0.0229 0.0212
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0052 0.0261 0.0261
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0101 0.0787 0.0778
Brugia malayi Trypsin family protein 0.0073 0.0488 0.0488
Plasmodium falciparum serine repeat antigen 5 0.0049 0.0229 0.0722
Echinococcus multilocularis calcium uptake protein 1 0.0043 0.0163 0.0155
Brugia malayi calpain family protein 1 0.0641 0.6527 0.6527
Loa Loa (eye worm) beta-lactamase 0.0035 0.0079 0.0079
Trypanosoma brucei centrin-3 0.0042 0.0153 0.0446
Onchocerca volvulus 0.0035 0.0079 0.02
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0049 0.0229 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0229 0.0678
Onchocerca volvulus Cathepsin L homolog 0.0049 0.0229 0.0578
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0968 1 1
Onchocerca volvulus 0.014 0.1197 0.3026
Onchocerca volvulus 0.0073 0.0488 0.1234
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0968 1 1
Brugia malayi MH2 domain containing protein 0.0139 0.1181 0.1181
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Echinococcus granulosus metabotropic glutamate receptor 2 0.0052 0.0261 0.0252
Onchocerca volvulus 0.0399 0.3954 1
Trypanosoma brucei Calpain-like protein 2 0.0073 0.0481 0.1456
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Entamoeba histolytica cysteine protease, putative 0.0086 0.0621 0.4123
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.0472
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Echinococcus granulosus cathepsin L cysteine protease 0.0086 0.0621 0.0613
Plasmodium falciparum serine repeat antigen 9 0.0049 0.0229 0.0722
Echinococcus multilocularis microtubule associated protein 2 0.0801 0.8222 0.8221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0229 0.0678
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1456
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0333 0.3251 0.3245
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0481 0.0472
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0049 0.0229 0.068
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0252 0.2383 0.2377
Echinococcus granulosus calpain 5 0.0242 0.228 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0049 0.0229 0.0678
Entamoeba histolytica protein kinase, putative 0.0169 0.1507 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0086 0.0621 0.0613
Giardia lamblia Cathepsin B precursor 0.0049 0.0229 0.0212
Brugia malayi PHD-finger family protein 0.0029 0.0015 0.0015
Entamoeba histolytica calpain family cysteine protease, putative 0.0073 0.0481 0.3191
Brugia malayi Receptor family ligand binding region containing protein 0.0052 0.0261 0.0261
Echinococcus multilocularis centrin 2 0.0042 0.0153 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0229 0.0678
Schistosoma mansoni protein kinase 0.0052 0.0261 0.0252
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Echinococcus multilocularis cathepsin b 0.0968 1 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Loa Loa (eye worm) glutamate receptor 1 0.0101 0.0787 0.0787
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0079 0.0217
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0086 0.0621 0.0613
Echinococcus granulosus centrin 2 0.0042 0.0153 0.0145
Brugia malayi Cathepsin L-like precursor 0.014 0.1197 0.1197
Leishmania major hypothetical protein, unknown function 0.0073 0.0481 0.1479
Brugia malayi Receptor family ligand binding region containing protein 0.0052 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0049 0.0229 0.0229
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0049 0.0229 0.068
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0042 0.0153 0.0145
Entamoeba histolytica cysteine proteinase, putative 0.014 0.1197 0.7942
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0101 0.0787 0.0778
Onchocerca volvulus 0.0073 0.0488 0.1234
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.018 0.0171
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0079 0.0217
Schistosoma mansoni glutamate receptor AMPA 0.0101 0.0787 0.0778
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Onchocerca volvulus 0.0042 0.0153 0.0388
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0079 0.0079
Trypanosoma cruzi conserved protein 0.0073 0.0481 0.0472
Echinococcus granulosus calbindin 32 0.0043 0.0163 0.0155
Schistosoma mansoni calmodulin 0.0042 0.0153 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0229 0.0678
Onchocerca volvulus 0.014 0.1197 0.3026
Schistosoma mansoni neuronal calcium sensor 0.0042 0.0153 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.1197 0.3664
Loa Loa (eye worm) hypothetical protein 0.0073 0.0488 0.0488
Brugia malayi beta-lactamase 0.0035 0.0079 0.0079
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0154 0.134 0.1332
Brugia malayi metabotropic glutamate receptor type 2 0.0052 0.0261 0.0261
Plasmodium falciparum calpain 0.0073 0.0481 0.3139
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0049 0.0229 0.068
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Echinococcus granulosus nmda type glutamate receptor 0.0052 0.0261 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0049 0.0229 0.0678
Giardia lamblia Cathepsin L precursor 0.0049 0.0229 0.0212
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Trypanosoma brucei centrin, putative 0.0042 0.0153 0.0446
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.2273
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0229 0.0229
Schistosoma mansoni cathepsin S (C01 family) 0.0049 0.0229 0.022
Trypanosoma cruzi cysteine peptidase, putative 0.014 0.1197 0.1189
Onchocerca volvulus 0.014 0.1197 0.3026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.018 0.0171
Echinococcus multilocularis calpain 7 (C02 family) 0.0242 0.228 0.2273
Onchocerca volvulus 0.0073 0.0488 0.1234
Brugia malayi cathepsin L-like precursor 0.0103 0.0804 0.0804
Trypanosoma brucei Calpain-like protein 1.1 0.0073 0.0481 0.1456
Trypanosoma cruzi cysteine peptidase, putative 0.014 0.1197 0.1189
Loa Loa (eye worm) hypothetical protein 0.014 0.1197 0.1197
Echinococcus granulosus calumenin 0.0043 0.0163 0.0155
Trypanosoma cruzi cysteine peptidase, putative 0.014 0.1197 0.1189
Loa Loa (eye worm) hypothetical protein 0.0223 0.2082 0.2082
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0229 0.0212
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0242 0.228 0.2273
Schistosoma mansoni glutamate receptor AMPA 0.0101 0.0787 0.0778
Trypanosoma brucei cysteine peptidase, putative 0.0073 0.0481 0.1456
Entamoeba histolytica cysteine protease, putative 0.0049 0.0229 0.1518
Trypanosoma cruzi centrin-3 0.0042 0.0153 0.0145
Echinococcus multilocularis cysteine protease 0.014 0.1197 0.1189
Entamoeba histolytica hypothetical protein 0.0052 0.0261 0.173
Brugia malayi Papain family cysteine protease containing protein 0.0086 0.0621 0.0621
Trichomonas vaginalis calmodulin, putative 0.0042 0.0153 0.0446
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0154 0.134 0.1332
Trypanosoma brucei calmodulin, putative 0.0043 0.0163 0.0476
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.0621 0.4123
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0242 0.228 0.2273
Entamoeba histolytica calmodulin, putative 0.0042 0.0153 0.1018
Trypanosoma brucei kinesin, putative 0.0169 0.1507 0.462
Loa Loa (eye worm) hypothetical protein 0.0399 0.3954 0.3954
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0481 0.0472
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.026 0.2473 0.5
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0079 0.032
Plasmodium vivax vivapain-1 0.0086 0.0621 0.2463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0229 0.0678
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0049 0.0229 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.014 0.1197 0.1189
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0154 0.134 0.1332
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0073 0.0488 0.048
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Echinococcus multilocularis EF hand domain containing family member A2 0.0042 0.0153 0.0145
Trichomonas vaginalis calcium binding protein, putative 0.0042 0.0153 0.0446
Trypanosoma brucei antigen, putative 0.0242 0.228 0.7005
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0042 0.0153 0.1018
Brugia malayi hypothetical protein 0.0073 0.0488 0.0488
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.018 0.0171
Schistosoma mansoni neuronal calcium sensor 0.0042 0.0153 0.0145
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0042 0.0153 0.0446
Echinococcus granulosus glutamate receptor 2 0.0052 0.0261 0.0252
Trypanosoma cruzi cruzipain precursor, putative 0.0037 0.01 0.0091
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0229 0.022
Trypanosoma brucei protein I/6 0.0042 0.0153 0.0446
Trichomonas vaginalis calcineurin B subunit, putative 0.0042 0.0153 0.0446
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0079 0.032
Brugia malayi cathepsin F-like cysteine proteinase 0.0037 0.01 0.01
Plasmodium falciparum cysteine proteinase falcipain 1 0.0086 0.0621 0.4483
Schistosoma mansoni calmodulin related calcium binding protein 0.0042 0.0153 0.0145
Leishmania major calcineurin B subunit, putative 0.0042 0.0153 0.0472
Loa Loa (eye worm) hypothetical protein 0.0472 0.4728 0.4728
Toxoplasma gondii cathepsin CPC1 0.0049 0.0229 0.0472
Schistosoma mansoni bromodomain containing protein 0.0073 0.0488 0.048
Schistosoma mansoni cercarial elastase (S01 family) 0.0073 0.0488 0.048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0481 0.0472
Schistosoma mansoni cathepsin C 0.0049 0.0229 0.022
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.0009 0.0009
Echinococcus multilocularis nmda type glutamate receptor 0.0362 0.3552 0.3547
Leishmania major i/6 autoantigen-like protein 0.0042 0.0153 0.0472
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.026 0.2473 0.5
Brugia malayi Cathepsin L-like precursor 0.014 0.1197 0.1197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0481 0.0472
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0049 0.0229 0.1518
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0079 0.0217
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Trichomonas vaginalis calcium binding proteins, putative 0.0042 0.0153 0.0446
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.014 0.1197 0.3664
Schistosoma mansoni tyrosine kinase 0.0052 0.0261 0.0252
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.7005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0261 0.0261
Leishmania major cathepsin L-like protease 0.014 0.1197 0.3681
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0049 0.0229 0.0678
Onchocerca volvulus 0.0035 0.0079 0.02
Echinococcus granulosus cathepsin L cysteine proteinase 0.014 0.1197 0.1189
Trichomonas vaginalis calcium binding protein, putative 0.0042 0.0153 0.0446
Echinococcus multilocularis glycoprotein Antigen 5 0.0073 0.0488 0.048
Giardia lamblia Cathepsin B precursor 0.0333 0.3251 1
Schistosoma mansoni microtubule-associated protein tau 0.0801 0.8222 0.8221
Giardia lamblia Cathepsin L precursor 0.0049 0.0229 0.0212
Onchocerca volvulus 0.0042 0.0153 0.0388
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.7013
Plasmodium falciparum serine repeat antigen 4 0.0049 0.0229 0.0722
Echinococcus multilocularis receptor type guanylyl cyclase 0.0052 0.0261 0.0252
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0481 0.1479
Plasmodium falciparum serine repeat antigen 3 0.0049 0.0229 0.0722
Onchocerca volvulus Cathepsin L homolog 0.014 0.1197 0.3026
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0086 0.0621 0.0613
Plasmodium falciparum cysteine proteinase falcipain 2b 0.014 0.1197 1
Leishmania major calmodulin-like protein 0.0042 0.0153 0.0472
Onchocerca volvulus 0.014 0.1197 0.3026
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0242 0.228 0.2273
Trypanosoma cruzi cysteine proteinase, putative 0.0086 0.0621 0.0613
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0229 0.0678
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0481 0.1456
Trypanosoma cruzi calmodulin, putative 0.0042 0.0153 0.0145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.018 0.0171
Brugia malayi calpain D 0.0073 0.0481 0.0481
Leishmania major calpain family cysteine protease-like protein 0.0073 0.0481 0.1479
Trypanosoma brucei calmodulin, putative 0.0042 0.0153 0.0446
Leishmania major phospholipase c-like protein 0.0042 0.0153 0.0472
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.1197 0.3664
Trypanosoma cruzi kinesin, putative 0.0169 0.1507 0.1499
Plasmodium falciparum serine repeat antigen 7 0.0049 0.0229 0.0722
Echinococcus multilocularis cathepsin L cysteine protease 0.014 0.1197 0.1189
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0683 0.6973 0.697
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0683 0.6973 0.697
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.0621 0.4123
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0252 0.2383 0.2377
Entamoeba histolytica calpain large subunit domain III containing protein 0.0169 0.1507 1
Loa Loa (eye worm) calpain D 0.0073 0.0481 0.0481
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0073 0.0488 0.048
Trichomonas vaginalis calpain, putative 0.0073 0.0481 0.1456
Schistosoma mansoni calpain-2 (C02 family) 0.0073 0.0481 0.0472
Entamoeba histolytica cysteine protease, putative 0.0049 0.0229 0.1518
Trypanosoma cruzi cysteine protease, putative 0.0086 0.0621 0.0613
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0052 0.0261 0.0261
Plasmodium falciparum cysteine proteinase falcipain 3 0.014 0.1197 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0242 0.228 0.7013
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.021
Schistosoma mansoni calpain C (C02 family) 0.0242 0.228 0.2273
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0261 0.0261
Brugia malayi EF hand family protein 0.0042 0.0153 0.0153

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 3.12 ug ml-1 Antibacterial activity against S. equi 02I001 ChEMBL. 2299643
MIC (functional) = 3.12 ug ml-1 Antibacterial activity was determined against C. perfringens 10A002 ChEMBL. 2299643
MIC (functional) = 6.25 ug ml-1 Antibacterial activity against S. aureus 01A005 ChEMBL. 2299643
MIC (functional) = 6.25 ug ml-1 Antibacterial activity S. zooepidemicus 02H001 ChEMBL. 2299643
Stimulation (functional) = 0.5 % In vitro rumen propionic acid test procedure, 20 ug/mL ChEMBL. 2299643
Stimulation (functional) = 1.02 % In vitro rumen propionic acid test procedure, 50 ug/mL ChEMBL. 2299643

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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