Detailed information for compound 30221

Basic information

Technical information
  • TDR Targets ID: 30221
  • Name: (2S)-2-(butylsulfonylamino)-3-[(9-pyridin-4-y l-9-azaspiro[5.5]undecane-3-carbonyl)amino]pr opanoic acid
  • MW: 480.621 | Formula: C23H36N4O5S
  • H donors: 3 H acceptors: 6 LogP: 2.42 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCS(=O)(=O)N[C@H](C(=O)O)CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1
  • InChi: 1S/C23H36N4O5S/c1-2-3-16-33(31,32)26-20(22(29)30)17-25-21(28)18-4-8-23(9-5-18)10-14-27(15-11-23)19-6-12-24-13-7-19/h6-7,12-13,18,20,26H,2-5,8-11,14-17H2,1H3,(H,25,28)(H,29,30)/t20-/m0/s1
  • InChiKey: WIZNRUGPDHNTSZ-FQEVSTJZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)-9-azaspiro[5.5]undecane-3-carbonyl]amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[oxo-[9-(4-pyridyl)-9-azaspiro[5.5]undecan-3-yl]methyl]amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[(9-pyridin-4-yl-9-azaspiro[5.5]undecan-3-yl)carbonylamino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)-9-azaspiro[5.5]undecane-3-carbonyl]amino]propionic acid
  • (2S)-2-(butylsulfonylamino)-3-[(9-pyridin-4-yl9-azaspiro[5.5]undecane-3-carbonyl)amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)9-azaspiro[5.5]undecane-3-carbonyl]amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)9-azaspiro[5.5]undecane-3-carbonyl]amino]propionic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) References
Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) integrin beta-2 Get druggable targets OG5_127959 All targets in OG5_127959
Echinococcus multilocularis integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma mansoni integrin beta subunit Get druggable targets OG5_127959 All targets in OG5_127959
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Brugia malayi Integrin beta pat-3 precursor Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum Integrin beta-PS precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
Echinococcus multilocularis integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus granulosus integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Brugia malayi Integrin alpha pat-2 precursor Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) integrin alpha pat-2 Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06464 integrin beta 2, putative Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma mansoni integrin alpha Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum IPR013513,Integrin alpha chain, C-terminal cytoplasmic region,domain-containing Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum Integrin beta-3 precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum ko:K06476 integrin alpha 2B, putative Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus granulosus integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica glycogen phosphorylase, putative 0.0117 0.0169 0.0586
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0421 0.0781 0.078
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Echinococcus granulosus cathepsin L 0.0384 0.0706 0.0706
Brugia malayi Peroxidasin 0.0281 0.0499 0.0497
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0046 0.0044
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0012 0.5
Plasmodium vivax NAD-dependent deacetylase, putative 0.0066 0.0066 0.0227
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0064 0.0061 0.0141
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Leishmania major histone deacetylase, putative 0.0093 0.012 0.0281
Schistosoma mansoni rab 0.023 0.0397 0.0397
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Onchocerca volvulus 0.023 0.0397 0.0812
Echinococcus multilocularis cathepsin b 0.4997 1 1
Loa Loa (eye worm) hypothetical protein 0.0411 0.0761 0.0759
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0143 0.0143
Echinococcus granulosus GPI anchor transamidase 0.0034 0.0002 0.0002
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0009 0.0009
Trypanosoma cruzi prolyl endopeptidase 0.2125 0.4213 0.4212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0384 0.0706 0.1968
Plasmodium vivax histone deacetylase, putative 0.0104 0.0143 0.0495
Echinococcus multilocularis glycogen phosphorylase 0.0117 0.0169 0.0169
Mycobacterium ulcerans NAD-dependent deacetylase 0.0066 0.0066 0.0329
Onchocerca volvulus Cell death protein 3 homolog 0.0322 0.0581 0.1199
Brugia malayi Serine protease Z688.6 precursor 0.0064 0.0061 0.0059
Leishmania major calpain family cysteine protease-like protein 0.0421 0.0781 0.1851
Entamoeba histolytica protein kinase, putative 0.1019 0.1985 0.6959
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0009 0.0018
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Brugia malayi proteasome subunit alpha type 2 0.004 0.0013 0.0012
Toxoplasma gondii proteasome beta subunit 0.004 0.0013 0.0028
Echinococcus granulosus calpain A 0.4079 0.8151 0.8151
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.2125 0.4213 0.4212
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0009 0.0008
Leishmania major hypothetical protein, conserved 0.0421 0.0781 0.1851
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.0013 0.0012
Schistosoma mansoni Nep2 peptidase (M13 family) 0.005 0.0033 0.0033
Giardia lamblia Hypothetical protein 0.0234 0.0405 0.1126
Brugia malayi hypothetical protein 0.0054 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.004 0.0013 0.0011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Schistosoma mansoni chromatin regulatory protein sir2 0.0066 0.0066 0.0066
Plasmodium falciparum plasmepsin V 0.0054 0.0042 0.0143
Schistosoma mansoni glycogen phosphorylase 0.0117 0.0169 0.0169
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.0432 0.043
Brugia malayi Eukaryotic aspartyl protease family protein 0.0054 0.0042 0.0041
Brugia malayi hypothetical protein 0.0276 0.0488 0.0487
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0066 0.0066 0.0066
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0258 0.0452 0.0452
Brugia malayi Cell death protein 3 precursor 0.0322 0.0581 0.058
Loa Loa (eye worm) transcription factor SMAD2 0.0133 0.02 0.0198
Trypanosoma cruzi centrin-3 0.0238 0.0411 0.041
Echinococcus granulosus tumor protein p63 0.0399 0.0736 0.0736
Echinococcus granulosus expressed protein 0.0441 0.082 0.082
Loa Loa (eye worm) ctsf protein 0.1449 0.2852 0.2851
Loa Loa (eye worm) sirtuin 4 0.0066 0.0066 0.0065
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0896 0.1739 1
Echinococcus multilocularis transmembrane protease serine 3 0.0181 0.0298 0.0298
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Echinococcus multilocularis integrin alpha 3 0.0142 0.0218 0.0218
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0248 0.0432 0.2443
Loa Loa (eye worm) trypsin family protein 0.0181 0.0298 0.0296
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0066 0.0066 0.0066
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Giardia lamblia 20S proteasome alpha subunit 6 0.004 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Toxoplasma gondii aldehyde dehydrogenase 0.0141 0.0217 0.051
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Giardia lamblia 20S proteasome alpha subunit 4 0.004 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0058 0.005 0.0049
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Echinococcus granulosus cathepsin l1 0.1017 0.1982 0.1982
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.023 0.0397 0.0395
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trypanosoma brucei histone deacetylase 4 0.0104 0.0143 0.0335
Echinococcus granulosus EF HAND 1 calcium binding site 0.023 0.0397 0.0397
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Onchocerca volvulus Chorion peroxidase homolog 0.0281 0.0499 0.1026
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.0013 0.0012
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.078
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Schistosoma mansoni inhibitor of apoptosis protein 0.0191 0.0318 0.0318
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1062 0.2073 0.4327
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0816 0.1576 0.4399
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0054 0.0042 0.0097
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Brugia malayi prolyl oligopeptidase family protein 0.1062 0.2073 0.2071
Giardia lamblia Alanyl dipeptidyl peptidase 0.0299 0.0536 0.1493
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1017 0.1982 0.5534
Onchocerca volvulus 0.0615 0.1172 0.2438
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.004 0.0013 0.0013
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.004 0.0013 0.0013
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Schistosoma mansoni cathepsin F (C01 family) 0.1449 0.2852 0.2852
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0012 0.0037
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0064 0.0061 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.0432 0.0803 0.0801
Trichomonas vaginalis calmodulin, putative 0.0238 0.0411 0.1145
Onchocerca volvulus Dual oxidase homolog 0.0281 0.0499 0.1026
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Echinococcus multilocularis neuronal calcium sensor 0.023 0.0397 0.0397
Trypanosoma cruzi hypothetical protein, conserved 0.0299 0.0536 0.0534
Leishmania major calmodulin-like protein 0.023 0.0397 0.0938
Echinococcus multilocularis programmed cell death protein 0.0238 0.0411 0.0411
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0214 0.0504
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0223 0.0222
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.023 0.0397 0.1386
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.1185 0.2319 0.2319
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Echinococcus multilocularis subfamily T1A non peptidase ue 0.004 0.0013 0.0013
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0012 0.0008
Onchocerca volvulus 0.1449 0.2852 0.5961
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0181 0.0298 0.0296
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Loa Loa (eye worm) hypothetical protein 0.1017 0.1982 0.1981
Giardia lamblia Encystation-specific protease 0.0384 0.0706 0.1968
Schistosoma mansoni reticulocalbin 0.0234 0.0405 0.0405
Brugia malayi 20S proteasome alpha5 subunit 0.004 0.0013 0.0012
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0064 0.0061 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0384 0.0706 0.1968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis cathepsin b 0.4997 1 1
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.004 0.0013 0.0028
Giardia lamblia Thymus-specific serine protease precursor 0.0064 0.0061 0.0166
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0384 0.0706 0.2471
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Trypanosoma brucei prolyl endopeptidase 0.2125 0.4213 1
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Toxoplasma gondii microneme protein MIC17B 0.0046 0.0025 0.0054
Plasmodium vivax proteasome subunit beta type-2, putative 0.009 0.0114 0.0395
Echinococcus multilocularis apoptotic protease activating factor 1 0.0182 0.03 0.03
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Echinococcus multilocularis endothelin converting enzyme 1 0.0099 0.0132 0.0132
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0384 0.0706 0.2471
Loa Loa (eye worm) prolyl oligopeptidase 0.0299 0.0536 0.0534
Onchocerca volvulus 0.0191 0.0318 0.0647
Echinococcus granulosus prolyl endopeptidase 0.2125 0.4213 0.4213
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0223 0.0223
Leishmania major metacaspase, putative 0.014 0.0214 0.0504
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.004 0.0013 0.0013
Echinococcus granulosus 20S proteasome subunit alpha 6 0.004 0.0013 0.0013
Loa Loa (eye worm) beta-lactamase 0.0038 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Echinococcus multilocularis proteasome (prosome, macropain) 0.0248 0.0432 0.0432
Loa Loa (eye worm) programmed cell death protein 6 0.0234 0.0405 0.0403
Onchocerca volvulus 0.1449 0.2852 0.5961
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.0013 0.0041
Trypanosoma cruzi calmodulin, putative 0.023 0.0397 0.0395
Brugia malayi cathepsin L-like cysteine proteinase 0.0384 0.0706 0.0704
Giardia lamblia 20S proteasome alpha subunit 7 0.004 0.0013 0.0033
Echinococcus multilocularis peroxidasin 0.0281 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0093 0.012 0.0118
Onchocerca volvulus 0.1449 0.2852 0.5961
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Plasmodium falciparum serine repeat antigen 8 0.0384 0.0706 0.2471
Echinococcus multilocularis calpain A 0.4079 0.8151 0.8151
Mycobacterium tuberculosis Probable peptidase 0.0896 0.1739 0.4803
Schistosoma mansoni hypothetical protein 0.0181 0.0298 0.0298
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0012 0.0012
Trypanosoma brucei proteasome beta 3 subunit, putative 0.004 0.0013 0.0028
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0142 0.0219 0.0516
Echinococcus granulosus chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0248 0.0432 0.1202
Leishmania major calmodulin, putative 0.023 0.0397 0.0938
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0384 0.0706 0.2471
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Onchocerca volvulus Peroxidasin homolog 0.0281 0.0499 0.1026
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Schistosoma mansoni calpain (C02 family) 0.144 0.2834 0.2834
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0285 0.0508 0.1414
Plasmodium vivax aspartyl proteinase, putative 0.0054 0.0042 0.0143
Trypanosoma cruzi histone deacetylase 1, putative 0.0093 0.012 0.0118
Mycobacterium ulcerans proteasome PrcB 0.0248 0.0432 0.2443
Echinococcus granulosus calcium uptake protein 1 0.0234 0.0405 0.0405
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Schistosoma mansoni aldehyde dehydrogenase 0.0141 0.0217 0.0217
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2125 0.4213 0.4213
Trypanosoma brucei Metacaspase-4 0.014 0.0214 0.0504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Onchocerca volvulus 0.1449 0.2852 0.5961
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Echinococcus multilocularis integrin alpha ps 0.004 0.0013 0.0013
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.0432 0.1202
Echinococcus granulosus calpain 0.144 0.2834 0.2834
Entamoeba histolytica hypothetical protein, conserved 0.0066 0.0066 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0384 0.0706 0.1968
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.004 0.0013 0.0041
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.0013 0.0041
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.009 0.0114 0.0114
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0012 0.0017
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1062 0.2073 0.2073
Trypanosoma cruzi kinesin, putative 0.1019 0.1985 0.1984
Echinococcus granulosus cathepsin l1 0.1449 0.2852 0.2852
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0018
Echinococcus multilocularis calumenin 0.0234 0.0405 0.0405
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0054 0.0042 0.0114
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Onchocerca volvulus 0.1449 0.2852 0.5961
Brugia malayi calpain family protein 1 0.3845 0.768 0.7679
Trypanosoma cruzi centrin, putative 0.0238 0.0411 0.041
Echinococcus multilocularis histone deacetylase 8 0.0045 0.0023 0.0023
Brugia malayi transcriptional regulator, Sir2 family protein 0.0066 0.0066 0.0065
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0142 0.0219 0.0516
Echinococcus granulosus histone deacetylase 7 0.0104 0.0143 0.0143
Toxoplasma gondii histone deacetylase HDAC5 0.0045 0.0023 0.0052
Trypanosoma brucei Component of motile flagella 41 0.023 0.0397 0.0938
Toxoplasma gondii microneme protein MIC17C 0.0046 0.0025 0.0054
Brugia malayi proteasome subunit alpha type 3 0.004 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0145 0.0225 0.0223
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0688 0.1319 0.1319
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0064 0.0061 0.0208
Toxoplasma gondii peptidase, T1 family protein 0.004 0.0013 0.0028
Echinococcus granulosus caspase 2 0.0322 0.0581 0.0581
Giardia lamblia Proteasome subunit beta type 2 0.009 0.0114 0.0315
Giardia lamblia 20S proteasome alpha subunit 5 0.004 0.0013 0.0033
Schistosoma mansoni histone deacetylase 1 2 3 0.0045 0.0023 0.0023
Toxoplasma gondii aspartyl protease 0.0054 0.0042 0.0097
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.181 0.358 1
Trypanosoma brucei hypothetical protein 0.0421 0.0781 0.1851
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0033 0.0033
Echinococcus granulosus peroxidasin 0.0281 0.0499 0.0499
Trypanosoma cruzi histone deacetylase 1, putative 0.0093 0.012 0.0118
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1062 0.2073 0.2073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Loa Loa (eye worm) MH2 domain-containing protein 0.0133 0.02 0.0198
Echinococcus multilocularis calbindin 32 0.0234 0.0405 0.0405
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0009 0.0022
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.004 0.0013 0.0028
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Brugia malayi Integrin beta pat-3 precursor 0.0378 0.0695 0.0693
Leishmania major histone deacetylase, putative 0.0104 0.0143 0.0335
Loa Loa (eye worm) hypothetical protein 0.006 0.0053 0.0051
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0141 0.0217 0.051
Loa Loa (eye worm) hypothetical protein 0.0299 0.0536 0.0534
Brugia malayi carbohydrate phosphorylase 0.0117 0.0169 0.0167
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Leishmania major proteasome alpha 2 subunit, putative 0.004 0.0013 0.0028
Echinococcus granulosus caspase 8 0.014 0.0214 0.0214
Schistosoma mansoni reticulocalbin 0.023 0.0397 0.0397
Schistosoma mansoni ap endonuclease 0.004 0.0012 0.0012
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.0013 0.0012
Plasmodium vivax aspartyl protease, putative 0.0054 0.0042 0.0143
Giardia lamblia Cathepsin B precursor 0.181 0.358 1
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.0013 0.0041
Mycobacterium tuberculosis Hypothetical protein 0.0443 0.0824 0.2263
Brugia malayi MH2 domain containing protein 0.0133 0.02 0.0198
Mycobacterium ulcerans proteasome PrcA 0.004 0.0013 0.0023
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.023 0.0397 0.0397
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Trichomonas vaginalis calpain, putative 0.0421 0.0781 0.2178
Plasmodium falciparum metacaspase 1 0.014 0.0214 0.0745
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Brugia malayi Integrin alpha cytoplasmic region family protein 0.014 0.0214 0.0213
Echinococcus multilocularis proteasome subunit beta type 6 0.004 0.0013 0.0013
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Leishmania major proteasome beta 3 subunit, putative 0.004 0.0013 0.0028
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0064 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0322 0.0581 0.058
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Schistosoma mansoni ef hand domain family member A2 0.023 0.0397 0.0397
Echinococcus granulosus calpain 5 0.144 0.2834 0.2834
Toxoplasma gondii histone deacetylase HDAC2 0.0093 0.012 0.0281
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0135 0.0135
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.004 0.0013 0.0013
Loa Loa (eye worm) proteasome subunit beta type 2 0.009 0.0114 0.0113
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0099 0.0132 0.0341
Plasmodium vivax vivapain-2 0.1449 0.2852 1
Leishmania major silent information regulator 2, putative 0.0258 0.0452 0.107
Loa Loa (eye worm) hypothetical protein 0.0099 0.0132 0.013
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0384 0.0706 0.2471
Loa Loa (eye worm) hypothetical protein 0.1449 0.2852 0.2851
Brugia malayi Angiotensin-converting enzyme family protein 0.1829 0.3619 0.3618
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Leishmania major programmed cell death 6 protein-like protein 0.023 0.0397 0.0938
Schistosoma mansoni Mername-AA248 (C02 family) 0.144 0.2834 0.2834
Entamoeba histolytica calcium-binding protein, putative 0.023 0.0397 0.1386
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0066 0.0066 0.0065
Echinococcus granulosus calpain A 0.144 0.2834 0.2834
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Entamoeba histolytica histone deacetylase, putative 0.0093 0.012 0.0415
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.004 0.0013 0.0041
Brugia malayi hypothetical protein 0.0178 0.0292 0.029
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Onchocerca volvulus 0.1449 0.2852 0.5961
Trypanosoma brucei proteasome beta-1 subunit, putative 0.004 0.0013 0.0028
Brugia malayi calpain D 0.0421 0.0781 0.078
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Toxoplasma gondii cathepsin CPC1 0.0384 0.0706 0.1672
Toxoplasma gondii histone deacetylase HDAC1 0.0104 0.0143 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Onchocerca volvulus Cathepsin L homolog 0.0384 0.0706 0.1461
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.023 0.0397 0.0938
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1449 0.2852 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0012 0.0025
Brugia malayi prolyl oligopeptidase family protein 0.0299 0.0536 0.0534
Loa Loa (eye worm) hypothetical protein 0.0432 0.0803 0.0801
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Schistosoma mansoni cathepsin F (C01 family) 0.1449 0.2852 0.2852
Giardia lamblia Proteasome subunit beta type 1 0.0142 0.0219 0.0608
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0023 0.0021
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0012 0.0011
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.004 0.0013 0.0041
Entamoeba histolytica hypothetical protein, conserved 0.0234 0.0405 0.1414
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Leishmania major cathepsin L-like protease 0.1505 0.2964 0.7034
Echinococcus multilocularis histone deacetylase 6 0.0111 0.0156 0.0156
Trypanosoma brucei histone deacetylase 1 0.0093 0.012 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0421 0.0781 0.2178
Echinococcus granulosus cathepsin L cysteine proteinase 0.1449 0.2852 0.2852
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2125 0.4213 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0009 0.0008
Loa Loa (eye worm) proteasome subunit beta type 1 0.0142 0.0219 0.0217
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Toxoplasma gondii histone deacetylase SIR2-like 0.0066 0.0066 0.0154
Brugia malayi Calmodulin-like protein 0.023 0.0397 0.0395
Onchocerca volvulus Peroxidasin homolog 0.0281 0.0499 0.1026
Giardia lamblia Transcriptional regulator, Sir2 family 0.0066 0.0066 0.0181
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Schistosoma mansoni chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trypanosoma cruzi conserved protein 0.0421 0.0781 0.078
Onchocerca volvulus 0.0046 0.0025 0.0032
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Echinococcus granulosus proteasome subunit beta t family 0.004 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0041
Echinococcus multilocularis caspase 8 0.014 0.0214 0.0214
Trichomonas vaginalis centrin, putative 0.023 0.0397 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Brugia malayi Papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Schistosoma mansoni gamma-secretase subunit aph-1 0.027 0.0477 0.0477
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0384 0.0706 0.1968
Echinococcus multilocularis centrin 2 0.023 0.0397 0.0397
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0061 0.014
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0223 0.0223
Echinococcus multilocularis cysteine protease 0.1449 0.2852 0.2852
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Onchocerca volvulus 0.0181 0.0298 0.0605
Trypanosoma cruzi hypothetical protein, conserved 0.0299 0.0536 0.0534
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1449 0.2852 0.2851
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Echinococcus granulosus calpain 7 C02 family 0.144 0.2834 0.2834
Brugia malayi histone deacetylase 11 0.0045 0.0023 0.0021
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4997 1 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0384 0.0706 0.2471
Plasmodium falciparum proteasome subunit beta type-6, putative 0.004 0.0013 0.0041
Toxoplasma gondii proteasome subunit beta type, putative 0.0248 0.0432 0.1021
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0258 0.0452 0.1259
Trypanosoma brucei kinesin, putative 0.1019 0.1985 0.471
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.1185 0.2319 0.2319
Toxoplasma gondii hypothetical protein 0.0046 0.0025 0.0054
Trypanosoma cruzi cysteine peptidase, putative 0.0816 0.1576 0.1575
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.023 0.0397 0.0395
Schistosoma mansoni chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Entamoeba histolytica calmodulin, putative 0.023 0.0397 0.1386
Toxoplasma gondii calcium-dependent protein kinase 0.0234 0.0405 0.0957
Toxoplasma gondii cathepsin CPC2 0.0384 0.0706 0.1672
Plasmodium vivax metacaspase 1, putative 0.014 0.0214 0.0745
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0421 0.0781 0.1851
Entamoeba histolytica prolyl oligopeptidase family protein 0.0299 0.0536 0.1874
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Plasmodium falciparum serine repeat antigen 5 0.0384 0.0706 0.2471
Mycobacterium leprae Conserved hypothetical protein 0.0443 0.0824 0.4712
Schistosoma mansoni integrin alpha-ps 0.0043 0.002 0.002
Entamoeba histolytica cysteine protease, putative 0.1449 0.2852 1
Trichomonas vaginalis calcineurin B subunit, putative 0.023 0.0397 0.1104
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Echinococcus granulosus cathepsin b 0.4997 1 1
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0066 0.0066 0.0066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis calcium uptake protein 1 0.0234 0.0405 0.0405
Loa Loa (eye worm) histone deacetylase 0.0104 0.0143 0.0141
Trypanosoma brucei histone deacetylase, putative 0.0104 0.0143 0.0335
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.181 0.358 0.3579
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0384 0.0706 0.1968
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0051 0.0035 0.007
Giardia lamblia Transglutaminase/protease, putative 0.0443 0.0824 0.2299
Onchocerca volvulus Cathepsin F homolog 0.1449 0.2852 0.5961
Plasmodium falciparum cysteine repeat modular protein 1 0.007 0.0075 0.0256
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0181 0.0298 0.0298
Schistosoma mansoni centrin 0.023 0.0397 0.0397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0384 0.0706 0.1968
Plasmodium vivax vivapain-1 0.0816 0.1576 0.5523
Brugia malayi Histone deacetylase family protein 0.0104 0.0143 0.0141
Schistosoma mansoni histone deacetylase 0.0093 0.012 0.012
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0009 0.0022
Giardia lamblia Proteasome subunit beta type 9 precursor 0.004 0.0013 0.0033
Trichomonas vaginalis peptide N-glycanase, putative 0.0443 0.0824 0.2299
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Loa Loa (eye worm) hypothetical protein 0.3424 0.6831 0.6831
Echinococcus granulosus geminin 0.0177 0.0289 0.0289
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0299 0.0536 0.1268
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Leishmania major calmodulin, putative 0.023 0.0397 0.0938
Plasmodium falciparum plasmepsin IX 0.0297 0.0532 0.1861
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0012 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0299 0.0536 0.1493
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.0488 0.0488
Trichomonas vaginalis myosin light chain 1, putative 0.023 0.0397 0.1104
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0816 0.1576 0.1576
Echinococcus granulosus sarcoplasmic calcium binding protein 0.023 0.0397 0.0397
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Brugia malayi transcriptional regulator, Sir2 family protein 0.0258 0.0452 0.0451
Toxoplasma gondii aspartyl protease ASP1 0.0054 0.0042 0.0097
Schistosoma mansoni survival motor neuron protein 0.0056 0.0046 0.0046
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.004 0.0013 0.0012
Echinococcus multilocularis dnaJ subfamily B 0.045 0.0839 0.0839
Mycobacterium tuberculosis Conserved protein 0.0443 0.0824 0.2263
Plasmodium vivax hypothetical protein, conserved 0.0066 0.0066 0.0227
Brugia malayi Histone deacetylase family protein 0.0104 0.0143 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.004 0.0013 0.0012
Trypanosoma cruzi metacaspase 5, putative 0.014 0.0214 0.0212
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Brugia malayi proteasome subunit alpha type 6 0.004 0.0013 0.0012
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Brugia malayi cathepsin Z-like cysteine proteinase 0.0384 0.0706 0.0704
Toxoplasma gondii centrin, putative 0.023 0.0397 0.0938
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Trypanosoma brucei protein I/6 0.023 0.0397 0.0938
Echinococcus multilocularis cathepsin L 0.0384 0.0706 0.0706
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0142 0.0219 0.0608
Leishmania major proteasome beta-1 subunit, putative 0.004 0.0013 0.0028
Giardia lamblia Proteasome subunit beta type 4 precursor 0.004 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0182 0.03 0.03
Trichomonas vaginalis calcium binding proteins, putative 0.023 0.0397 0.1104
Brugia malayi histone deacetylase 1 (HD1) 0.0093 0.012 0.0118
Plasmodium falciparum serine repeat antigen 7 0.0384 0.0706 0.2471
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0384 0.0706 0.2471
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.0013 0.0041
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Onchocerca volvulus 0.0181 0.0298 0.0605
Schistosoma mansoni integrin alpha 0.0185 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Leishmania major oligopeptidase b 0.0896 0.1739 0.4125
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0022
Trypanosoma cruzi Aph-1 protein, putative 0.0105 0.0145 0.0143
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0191 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0045 0.0023 0.0021
Entamoeba histolytica glycogen phosphorylase, putative 0.0117 0.0169 0.0586
Toxoplasma gondii prolyl endopeptidase 0.2125 0.4213 1
Toxoplasma gondii aspartyl protease ASP3 0.0297 0.0532 0.1259
Plasmodium falciparum histone deacetylase 2 0.0104 0.0143 0.0495
Plasmodium vivax aspartyl proteinase, putative 0.0054 0.0042 0.0143
Trypanosoma cruzi I/6 autoantigen, putative 0.023 0.0397 0.0395
Schistosoma mansoni peroxidasin 0.0281 0.0499 0.0499
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.0217 0.1198
Echinococcus multilocularis EF hand domain containing family member A2 0.0234 0.0405 0.0405
Toxoplasma gondii PAN/Apple domain-containing protein 0.0046 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trypanosoma cruzi cysteine peptidase, putative 0.1449 0.2852 0.2851
Trypanosoma brucei caltractin, putative 0.0238 0.0411 0.0973
Echinococcus granulosus caspase 0.0426 0.0791 0.0791
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0009 0.0008
Trypanosoma brucei metacaspase MCA3 0.014 0.0214 0.0504
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.4075 0.8144 0.8144
Brugia malayi cathepsin L precursor 0.0384 0.0706 0.0704
Schistosoma mansoni cathepsin D (A01 family) 0.0338 0.0614 0.0614
Schistosoma mansoni caspase-7 (C14 family) 0.0322 0.0581 0.0581
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0135 0.0135
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.004 0.0013 0.0013
Trypanosoma brucei C-8 sterol isomerase, putative 0.037 0.0678 0.1605
Loa Loa (eye worm) hypothetical protein 0.014 0.0214 0.0213
Plasmodium vivax unspecified product 0.0432 0.0803 0.2811
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0285 0.0508 0.0508
Echinococcus multilocularis calmodulin 0.023 0.0397 0.0397
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0057 0.0049 0.0047
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Entamoeba histolytica hypothetical protein 0.0384 0.0706 0.2471
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Brugia malayi hypothetical protein 0.0181 0.0298 0.0296
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Schistosoma mansoni peroxidasin 0.0281 0.0499 0.0499
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.004 0.0013 0.0028
Onchocerca volvulus 0.1449 0.2852 0.5961
Brugia malayi Thioredoxin family protein 0.0443 0.0824 0.0823
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.0013 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0135 0.0135
Toxoplasma gondii hypothetical protein 0.0421 0.0781 0.1851
Echinococcus granulosus proteasome subunit beta type 7 0.004 0.0013 0.0013
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0816 0.1576 0.1575
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.023 0.0397 0.0397
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0141 0.0217 0.0575
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Trypanosoma cruzi C-8 sterol isomerase, putative 0.037 0.0678 0.0676
Leishmania major hypothetical protein, unknown function 0.0421 0.0781 0.1851
Onchocerca volvulus 0.0181 0.0298 0.0605
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0688 0.1319 0.1318
Plasmodium vivax histone deacetylase 2, putative 0.0104 0.0143 0.0495
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trypanosoma brucei metacaspase MCA2 0.014 0.0214 0.0504
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0012 0.003
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.004 0.0013 0.0013
Onchocerca volvulus 0.0181 0.0298 0.0605
Trypanosoma brucei I/6 autoantigen 0.023 0.0397 0.0938
Echinococcus granulosus tissue type plasminogen activator 0.007 0.0075 0.0075
Trypanosoma brucei Calpain-like protein 1.2 0.0421 0.0781 0.1851
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.004 0.0013 0.0013
Trichomonas vaginalis calpain, putative 0.0421 0.0781 0.2178
Echinococcus multilocularis hypothetical protein 0.144 0.2834 0.2834
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0061 0.0166
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Plasmodium falciparum serine repeat antigen 3 0.0384 0.0706 0.2471
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0432 0.0803 0.0801
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0013 0.0013
Toxoplasma gondii microneme protein MIC17A 0.0046 0.0025 0.0054
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0066 0.0066 0.0154
Plasmodium falciparum centrin-1 0.023 0.0397 0.1386
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0012 0.0012
Plasmodium vivax aspartyl protease, putative 0.0297 0.0532 0.1861
Loa Loa (eye worm) histone deacetylase 1 0.0093 0.012 0.0118
Schistosoma mansoni calmodulin 0.023 0.0397 0.0397
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Plasmodium vivax centrin-1, putative 0.023 0.0397 0.1386
Loa Loa (eye worm) calpain family protein 1 0.3845 0.768 0.7679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Leishmania major centrin, putative 0.023 0.0397 0.0938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Brugia malayi Peptidase C13 family protein 0.0147 0.023 0.0228
Plasmodium vivax hypothetical protein, conserved 0.0299 0.0536 0.1874
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0248 0.0432 0.1021
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0023 0.0023
Trypanosoma cruzi Aph-1 protein, putative 0.0105 0.0145 0.0143
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.1017 0.1982 0.1981
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0258 0.0452 0.0451
Trypanosoma brucei proteasome beta 6 subunit 0.0142 0.0219 0.0516
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.0013 0.0041
Leishmania major cathepsin L-like protease 0.1505 0.2964 0.7034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0012 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Loa Loa (eye worm) hypothetical protein 0.0049 0.0031 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Echinococcus granulosus calmodulin 0.023 0.0397 0.0397
Echinococcus granulosus proteasome subunit alpha type 2 0.004 0.0013 0.0013
Toxoplasma gondii calmodulin CAM1 0.0234 0.0405 0.0957
Schistosoma mansoni microtubule-associated protein tau 0.0796 0.1536 0.1536
Toxoplasma gondii proteasome subunit 0.004 0.0013 0.0028
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0688 0.1319 0.3128
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0299 0.0536 0.1493
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0075 0.0073
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Plasmodium vivax serine-repeat antigen (SERA) 0.0384 0.0706 0.2471
Schistosoma mansoni centrin-related 0.023 0.0397 0.0397
Echinococcus granulosus programmed cell death protein 0.0238 0.0411 0.0411
Toxoplasma gondii cathepsin CPL 0.1449 0.2852 0.6768
Onchocerca volvulus 0.0046 0.0025 0.0032
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Plasmodium vivax plasmepsin IV, putative 0.0054 0.0042 0.0143
Trypanosoma cruzi major cysteine proteinase, putative 0.0384 0.0706 0.0704
Loa Loa (eye worm) transcriptional regulator 0.0066 0.0066 0.0065
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0384 0.0706 0.0706
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0234 0.0405 0.0405
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0066 0.0066 0.0227
Plasmodium vivax plasmepsin V, putative 0.0054 0.0042 0.0143
Echinococcus granulosus Dipeptidyl peptidase 9 0.0688 0.1319 0.1319
Toxoplasma gondii microneme protein MIC4 0.0046 0.0025 0.0054
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Onchocerca volvulus Cathepsin L homolog 0.1449 0.2852 0.5961
Echinococcus multilocularis inhibitor of apoptosis protein 0.0191 0.0318 0.0318
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0384 0.0706 0.2471
Echinococcus multilocularis Glycosyl transferase, family 35 0.0117 0.0169 0.0169
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0141 0.0217 0.0217
Trypanosoma brucei proteasome beta 2 subunit, putative 0.004 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0191 0.0318 0.0316
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Brugia malayi proteasome subunit beta type 2 0.009 0.0114 0.0113
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0142 0.0219 0.0763
Toxoplasma gondii heat shock protein hslv, putative 0.004 0.0013 0.0028
Schistosoma mansoni neprilysin-2 (M13 family) 0.005 0.0033 0.0033
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0191 0.0318 0.0316
Brugia malayi calpain 5 0.0421 0.0781 0.078
Trypanosoma cruzi calmodulin, putative 0.023 0.0397 0.0395
Plasmodium vivax proteasome subunit alpha type-5, putative 0.004 0.0013 0.0041
Brugia malayi Serine carboxypeptidase S28 family protein 0.0064 0.0061 0.0059
Brugia malayi fibroinase precursor 0.0384 0.0706 0.0704
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0432 0.0803 0.0801
Leishmania major centrin, putative 0.023 0.0397 0.0938
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0023 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.004 0.0013 0.0012
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Leishmania major centrin, putative,caltractin, putative 0.023 0.0397 0.0938
Entamoeba histolytica hypothetical protein, conserved 0.0299 0.0536 0.1874
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0142 0.0219 0.0219
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.004 0.0013 0.0028
Trypanosoma cruzi calmodulin, putative 0.023 0.0397 0.0395
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Plasmodium vivax proteasome subunit alpha type-4, putative 0.004 0.0013 0.0041
Trypanosoma brucei Aph-1 protein, putative 0.0105 0.0145 0.034
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0299 0.0536 0.0536
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0054 0.0042 0.0042
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Brugia malayi transcriptional regulator, Sir2 family protein 0.0066 0.0066 0.0065
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0034 0.0002 0.0002
Echinococcus multilocularis acylamino acid releasing enzyme 0.0299 0.0536 0.0536
Plasmodium vivax proteasome subunit beta type-3, putative 0.004 0.0013 0.0041
Echinococcus multilocularis cathepsin L cysteine protease 0.1449 0.2852 0.2852
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Mycobacterium leprae probable zinc metalloprotease 0.0099 0.0132 0.0709
Onchocerca volvulus 0.0281 0.0499 0.1026
Loa Loa (eye worm) hypothetical protein 0.0178 0.0292 0.029
Onchocerca volvulus 0.0056 0.0046 0.0077
Echinococcus multilocularis integrin beta 2 0.028 0.0497 0.0497
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4997 1 1
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Leishmania major kinesin, putative 0.1019 0.1985 0.471
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.004 0.0013 0.0028
Loa Loa (eye worm) glycogen phosphorylase 0.0117 0.0169 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0397 0.1104
Onchocerca volvulus 0.0182 0.03 0.0609
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Plasmodium vivax proteasome subunit beta type-1, putative 0.0142 0.0219 0.0763
Plasmodium vivax proteasome subunit alpha type-2, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Plasmodium falciparum cysteine proteinase falcipain 1 0.0816 0.1576 0.5523
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0214 0.0504
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0013 0.0013
Echinococcus multilocularis tumor protein p63 0.0399 0.0736 0.0736
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.078
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trypanosoma brucei histone deacetylase 3 0.0104 0.0143 0.0335
Brugia malayi cathepsin F-like cysteine proteinase 0.0432 0.0803 0.0801
Echinococcus multilocularis cathepsin L cysteine protease 0.1449 0.2852 0.2852
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0041
Brugia malayi cathepsin L-like precursor 0.1017 0.1982 0.1981
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0064 0.0061 0.0166
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0141 0.0217 0.0217
Trichomonas vaginalis calmodulin-2, putative 0.023 0.0397 0.1104
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0426 0.0791 0.0791
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.009 0.0114 0.0113
Onchocerca volvulus 0.0281 0.0499 0.1026
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Trypanosoma brucei calmodulin, putative 0.0234 0.0405 0.0957
Brugia malayi Cathepsin L-like cysteine proteinase 0.1017 0.1982 0.1981
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0422 0.1147
Echinococcus granulosus apoptotic protease activating factor 1 0.0182 0.03 0.03
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Trypanosoma brucei cysteine peptidase, putative 0.0421 0.0781 0.1851
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.023 0.0397 0.0395
Brugia malayi histone deacetylase 3 (HD3) 0.0093 0.012 0.0118
Echinococcus multilocularis EF HAND 1, calcium binding site 0.023 0.0397 0.0397
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Loa Loa (eye worm) proteasome subunit alpha type 2 0.004 0.0013 0.0012
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0066 0.0066 0.0154
Schistosoma mansoni calpain-2 (C02 family) 0.0421 0.0781 0.0781
Plasmodium vivax proteasome subunit beta type-7, putative 0.004 0.0013 0.0041
Schistosoma mansoni chromatin regulatory protein sir2 0.0066 0.0066 0.0066
Schistosoma mansoni integrin alpha-ps 0.0083 0.01 0.01
Brugia malayi Cathepsin L-like precursor 0.0432 0.0803 0.0801
Trypanosoma cruzi kinesin, putative 0.1019 0.1985 0.1984
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.023 0.0397 0.0938
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Echinococcus granulosus transmembrane protease serine 3 0.0181 0.0298 0.0298
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0035 0.0116
Brugia malayi Papain family cysteine protease containing protein 0.0816 0.1576 0.1575
Schistosoma mansoni cathepsin C 0.0384 0.0706 0.0706
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Onchocerca volvulus 0.0046 0.0025 0.0032
Echinococcus multilocularis cysteine protease 0.1449 0.2852 0.2852
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Brugia malayi hypothetical protein 0.0182 0.03 0.0298
Giardia lamblia Cathepsin B precursor 0.181 0.358 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0009 0.0009
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Trypanosoma brucei centrin, putative 0.023 0.0397 0.0938
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Onchocerca volvulus 0.0792 0.1528 0.3185
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.004 0.0013 0.0028
Plasmodium vivax histone deacetylase 1, putative 0.0093 0.012 0.0415
Schistosoma mansoni hypothetical protein 0.004 0.0013 0.0013
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Leishmania major protein kinase, putative 0.023 0.0397 0.0938
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.004 0.0013 0.0041
Plasmodium falciparum plasmepsin VI 0.0054 0.0042 0.0143
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0223 0.0223
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.0013 0.0012
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.004 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0421 0.0781 0.0781
Loa Loa (eye worm) calpain 0.144 0.2834 0.2833
Schistosoma mansoni aldehyde dehydrogenase 0.0141 0.0217 0.0217
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.0013 0.0012
Onchocerca volvulus 0.01 0.0135 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.004 0.0013 0.0041
Toxoplasma gondii hypothetical protein 0.0046 0.0025 0.0054
Giardia lamblia Hypothetical protein 0.0443 0.0824 0.2299
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Echinococcus granulosus proteasome prosome macropain subunit beta 0.009 0.0114 0.0114
Entamoeba histolytica cysteine proteinase, putative 0.1449 0.2852 1
Schistosoma mansoni cathepsin B (C01 family) 0.0384 0.0706 0.0706
Trypanosoma cruzi cruzipain precursor, putative 0.1505 0.2964 0.2963
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Plasmodium falciparum plasmepsin III 0.0054 0.0042 0.0143
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.0013 0.0012
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Leishmania major calpain protease-like protein 0.0421 0.0781 0.1851
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0264 0.0465 0.1627
Onchocerca volvulus 0.0178 0.0292 0.0593
Schistosoma mansoni hypothetical protein 0.045 0.0839 0.0839
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0688 0.1319 0.1318
Echinococcus multilocularis integrin alpha ps 0.0083 0.01 0.01
Trypanosoma cruzi cysteine protease, putative 0.0816 0.1576 0.1575
Echinococcus granulosus histone deacetylase 8 0.0045 0.0023 0.0023
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0299 0.0536 0.0536
Brugia malayi Proteasome subunit alpha type 1 0.004 0.0013 0.0012
Plasmodium falciparum serine repeat antigen 2 0.0384 0.0706 0.2471
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Brugia malayi beta-lactamase family protein 0.0038 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0191 0.0318 0.0318
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.0013 0.0028
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Schistosoma mansoni hypothetical protein 0.023 0.0397 0.0397
Trichomonas vaginalis calcineurin B subunit, putative 0.0234 0.0405 0.1126
Giardia lamblia Cathepsin B precursor 0.181 0.358 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.023 0.0397 0.1386
Trypanosoma cruzi major cysteine proteinase, putative 0.0439 0.0818 0.0816
Schistosoma mansoni integrin beta subunit 0.0223 0.0381 0.0381
Trypanosoma cruzi oligopeptidase b 0.0896 0.1739 0.1737
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4997 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Trypanosoma cruzi cysteine peptidase, putative 0.1505 0.2964 0.2963
Echinococcus granulosus EF hand domain containing family member A2 0.023 0.0397 0.0397
Onchocerca volvulus 0.0281 0.0499 0.1026
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0384 0.0706 0.2471
Schistosoma mansoni hypothetical protein 0.0113 0.0161 0.0161
Echinococcus multilocularis calpain family protein 1, d 0.2826 0.5627 0.5627
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.023 0.0397 0.1104
Toxoplasma gondii centrin 0.023 0.0397 0.0938
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0013 0.0013
Giardia lamblia 20S proteasome alpha subunit 1 0.004 0.0013 0.0033
Plasmodium vivax serine-repeat antigen (SERA) 0.0384 0.0706 0.2471
Loa Loa (eye worm) transcriptional regulator 0.0066 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.3845 0.768 0.7679
Onchocerca volvulus Peroxidase homolog 0.0281 0.0499 0.1026
Onchocerca volvulus 0.0046 0.0025 0.0032
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0816 0.1576 0.1576
Schistosoma mansoni hypothetical protein 0.0056 0.0046 0.0046
Plasmodium falciparum proteasome subunit beta type-2, putative 0.009 0.0114 0.0395
Echinococcus granulosus Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.005 0.0033 0.0033
Echinococcus granulosus calbindin 32 0.0234 0.0405 0.0405
Plasmodium falciparum plasmepsin I 0.0054 0.0042 0.0143
Trichomonas vaginalis calmodulin, putative 0.0234 0.0405 0.1126
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.004 0.0013 0.0012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0009 0.0009
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0093 0.012 0.033
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0064 0.0061 0.0059
Onchocerca volvulus Legumain homolog 0.0147 0.023 0.0462
Plasmodium falciparum histone deacetylase 1 0.0093 0.012 0.0415
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Entamoeba histolytica cysteine proteinase, putative 0.1017 0.1982 0.6948
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trypanosoma brucei Calpain-like protein 2 0.0421 0.0781 0.1851
Toxoplasma gondii kringle domain-containing protein 0.007 0.0075 0.0174
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.004 0.0013 1
Brugia malayi Pre-SET motif family protein 0.0696 0.1334 0.1333
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.023 0.023
Toxoplasma gondii histone deacetylase HDAC3 0.0093 0.012 0.0281
Echinococcus granulosus cathepsin b 0.4997 1 1
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.004 0.0013 0.0041
Plasmodium falciparum plasmepsin II 0.0054 0.0042 0.0143
Onchocerca volvulus 0.0046 0.0025 0.0032
Entamoeba histolytica prolyl oligopeptidase family protein 0.0299 0.0536 0.1874
Loa Loa (eye worm) calpain D 0.0421 0.0781 0.078
Trypanosoma brucei calpain, putative 0.0421 0.0781 0.1851
Brugia malayi Proteasome subunit alpha type 7-1 0.004 0.0013 0.0012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0696 0.1334 0.1333
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0384 0.0706 0.0704
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.023 0.0397 0.0395
Loa Loa (eye worm) hypothetical protein 0.0099 0.0132 0.013
Loa Loa (eye worm) integrin beta-2 0.0378 0.0695 0.0693
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4997 1 1
Schistosoma mansoni glycogen phosphorylase 0.0051 0.0035 0.0035
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0181 0.0298 0.0298
Plasmodium vivax vivapain-3 0.0816 0.1576 0.5523
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.004 0.0013 0.0012
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0384 0.0706 0.2471
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0066 0.0066 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0816 0.1576 0.4399
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0234 0.0405 0.0403
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Echinococcus granulosus histone deacetylase 6 0.0111 0.0156 0.0156
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.004 0.0013 0.0041
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.1851
Echinococcus granulosus integrin alpha ps 0.004 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Plasmodium falciparum histone deacetylase, putative 0.0104 0.0143 0.0495
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Trypanosoma brucei prolyl oligopeptidase, putative 0.0896 0.1739 0.4125
Trypanosoma cruzi histone deacetylase, putative 0.0104 0.0143 0.0141
Toxoplasma gondii troponin c, isotype gamma, putative 0.023 0.0397 0.0938
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.0217 0.1198
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0688 0.1319 0.3128
Echinococcus multilocularis caspase 2 0.0322 0.0581 0.0581
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0816 0.1576 0.3738
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0384 0.0706 0.2471
Echinococcus granulosus neurocalcin 0.023 0.0397 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Brugia malayi Blistered cuticle protein 3 0.0281 0.0499 0.0497
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Toxoplasma gondii hypothetical protein 0.0299 0.0536 0.1268
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Loa Loa (eye worm) histone deacetylase 3 0.0093 0.012 0.0118
Loa Loa (eye worm) hypothetical protein 0.023 0.0397 0.0395
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.004 0.0013 0.0013
Onchocerca volvulus 0.0181 0.0298 0.0605
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0066 0.0066 0.0227
Trypanosoma cruzi centrin, putative 0.0238 0.0411 0.041
Echinococcus multilocularis calpain 0.144 0.2834 0.2834
Onchocerca volvulus Cathepsin L homolog 0.1449 0.2852 0.5961
Schistosoma mansoni glycogen phosphorylase 0.0117 0.0169 0.0169
Brugia malayi calcium-binding protein 0.023 0.0397 0.0395
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0384 0.0706 0.2471
Loa Loa (eye worm) fibroinase 0.1449 0.2852 0.2851
Mycobacterium ulcerans hypothetical protein 0.0443 0.0824 0.4712
Echinococcus multilocularis programmed cell death protein 0.0238 0.0411 0.0411
Echinococcus multilocularis microtubule associated protein 2 0.0796 0.1536 0.1536
Trypanosoma cruzi 20S proteasome subunit 0.009 0.0114 0.0113
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0075 0.0075
Trichomonas vaginalis hypothetical protein 0.0421 0.0781 0.2178
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Trypanosoma brucei centrin, putative 0.023 0.0397 0.0938
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0688 0.1319 0.3128
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Trypanosoma cruzi metacaspase 5, putative 0.014 0.0214 0.0212
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0384 0.0706 0.2471
Entamoeba histolytica cysteine proteinase, putative 0.1449 0.2852 1
Loa Loa (eye worm) histone deacetylase 11 0.0045 0.0023 0.0021
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0064 0.0061 0.0208
Echinococcus granulosus glycoprotein Antigen 5 0.0181 0.0298 0.0298
Plasmodium falciparum serine repeat antigen 4 0.0384 0.0706 0.2471
Echinococcus granulosus enteropeptidase 0.0181 0.0298 0.0298
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0142 0.0219 0.0217
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0142 0.0219 0.0219
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Giardia lamblia Alanyl dipeptidyl peptidase 0.0299 0.0536 0.1493
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0896 0.1739 0.4125
Onchocerca volvulus 0.0058 0.005 0.0086
Onchocerca volvulus 0.0046 0.0025 0.0032
Giardia lamblia Hypothetical protein 0.0384 0.0706 0.1968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Schistosoma mansoni chromatin regulatory protein sir2 0.0285 0.0508 0.0508
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0066 0.0066 0.0158
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0189 0.0313 0.0312
Leishmania major hypothetical protein, conserved 0.0038 0.0009 0.0018
Entamoeba histolytica calcium binding family protein 0.023 0.0397 0.1386
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.023 0.0397 0.0395
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Echinococcus granulosus histone deacetylase 6 0.0104 0.0143 0.0143
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0054 0.0042 0.0041
Echinococcus multilocularis glycogen phosphorylase 0.0117 0.0169 0.0169
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0099 0.0132 0.013
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0012 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0384 0.0706 0.1968
Echinococcus multilocularis geminin 0.0177 0.0289 0.0289
Echinococcus multilocularis Mastin 0.0181 0.0298 0.0298
Echinococcus multilocularis histone deacetylase 3 0.0093 0.012 0.012
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0896 0.1739 0.4803
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2125 0.4213 0.4213
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0258 0.0452 0.0451
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0066 0.0066 0.0066
Trichomonas vaginalis glycogen phosphorylase, putative 0.0117 0.0169 0.0466
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Plasmodium falciparum proteasome subunit beta type-7, putative 0.004 0.0013 0.0041
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.004 0.0013 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0234 0.0405 0.1414
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Loa Loa (eye worm) peptidase family M13 containing protein 0.0073 0.008 0.0078
Loa Loa (eye worm) hypothetical protein 0.4997 1 1
Loa Loa (eye worm) EF hand family protein 0.023 0.0397 0.0395
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Echinococcus multilocularis histone deacetylase 1 0.0093 0.012 0.012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Echinococcus granulosus glycogen phosphorylase 0.0117 0.0169 0.0169
Loa Loa (eye worm) calpain 5 0.1019 0.1985 0.1984
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.004 0.0013 0.0041
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0867 0.168 0.168
Plasmodium falciparum cysteine proteinase falcipain 3 0.1449 0.2852 1
Echinococcus granulosus microtubule associated protein 2 0.0796 0.1536 0.1536
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Echinococcus granulosus histone deacetylase 6 0.0104 0.0143 0.0143
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Loa Loa (eye worm) proteasome subunit alpha type 6 0.004 0.0013 0.0012
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.0488 0.0488
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0142 0.0219 0.0217
Loa Loa (eye worm) transcriptional regulator 0.0258 0.0452 0.0451
Toxoplasma gondii proteasome subunit alpha1, putative 0.004 0.0013 0.0028
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0384 0.0706 0.2471
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.037 0.0678 0.0676
Trypanosoma brucei ATP-dependent protease subunit HslV 0.004 0.0013 0.0028
Leishmania major hypothetical protein, conserved 0.007 0.0075 0.0174
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.004 0.0013 0.0012
Plasmodium falciparum serine repeat antigen 6 0.0384 0.0706 0.2471
Leishmania major cathepsin L-like protease 0.1505 0.2964 0.7034
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.004 0.0013 0.0013
Trichomonas vaginalis esterase, putative 0.0038 0.0009 0.0022
Schistosoma mansoni histone deacetylase 4 5 0.0104 0.0143 0.0143
Toxoplasma gondii histone deacetylase HDAC4 0.0045 0.0023 0.0051
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Trichomonas vaginalis calpain, putative 0.0421 0.0781 0.2178
Onchocerca volvulus 0.0046 0.0025 0.0032
Trypanosoma cruzi calpain cysteine peptidase, putative 0.144 0.2834 0.2833
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0061 0.0166
Trypanosoma brucei proteasome subunit beta type-2, putative 0.009 0.0114 0.0267
Brugia malayi prolyl oligopeptidase family protein 0.0688 0.1319 0.1318
Brugia malayi Trypsin-like protease protein 5 0.0181 0.0298 0.0296
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Schistosoma mansoni calpain-7 (C02 family) 0.1443 0.284 0.284
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Giardia lamblia Sirtuin type 2 0.0066 0.0066 0.0181
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0191 0.0318 0.0318
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.004 0.0013 0.0011
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Brugia malayi calpain family protein 1 0.3845 0.768 0.7679
Loa Loa (eye worm) hypothetical protein 0.014 0.0214 0.0212
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Mycobacterium tuberculosis Conserved hypothetical protein 0.0443 0.0824 0.2263
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Schistosoma mansoni caspase-7 (C14 family) 0.0426 0.0791 0.0791
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0012 0.003
Echinococcus multilocularis Proteasome, subunit alpha beta 0.004 0.0013 0.0013
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0046 0.0025 0.0054
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Loa Loa (eye worm) peptidase C13 family protein 0.0147 0.023 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis cathepsin L 0.0816 0.1576 0.1576
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Brugia malayi Papain family cysteine protease containing protein 0.1449 0.2852 0.2851
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.0013 0.0041
Trichomonas vaginalis calcium binding protein, putative 0.0238 0.0411 0.1145
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0064 0.0061 0.0208
Echinococcus granulosus integrin alpha ps 0.0083 0.01 0.01
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0384 0.0706 0.0706
Leishmania major proteasome beta 7 subunit, putative 0.004 0.0013 0.0028
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Brugia malayi aspartic protease BmAsp-1, identical 0.0054 0.0042 0.0041
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0248 0.0432 0.043
Trypanosoma brucei calmodulin, putative 0.023 0.0397 0.0938
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Brugia malayi hypothetical protein 0.0057 0.0049 0.0047
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.0013 0.0013
Onchocerca volvulus 0.2405 0.4778 1
Brugia malayi proteasome subunit beta type 1 0.0142 0.0219 0.0217
Entamoeba histolytica grainin, putative 0.0234 0.0405 0.1414
Echinococcus multilocularis histone deacetylase 7 0.0104 0.0143 0.0143
Echinococcus granulosus Glycosyl transferase family 35 0.0117 0.0169 0.0169
Trypanosoma brucei hypothetical protein, conserved 0.023 0.0397 0.0938
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.004 0.0013 0.0041
Brugia malayi programmed cell death protein 6 0.023 0.0397 0.0395
Trypanosoma brucei histone deacetylase 2 0.0045 0.0023 0.0051
Brugia malayi prolyl oligopeptidase family protein 0.2125 0.4213 0.4212
Schistosoma mansoni histone deacetylase 0.0093 0.012 0.012
Echinococcus granulosus histone deacetylase 0.0104 0.0143 0.0143
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1449 0.2852 0.2852
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Plasmodium vivax proteasome subunit beta type-4, putative 0.004 0.0013 0.0041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Echinococcus granulosus endothelin converting enzyme 1 0.0099 0.0132 0.0132
Plasmodium falciparum calpain 0.0421 0.0781 0.2735
Brugia malayi beta-lactamase 0.0038 0.0009 0.0008
Plasmodium vivax proteasome subunit alpha type-7, putative 0.004 0.0013 0.0041
Leishmania major proteasome beta 2 subunit, putative 0.009 0.0114 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Brugia malayi Cathepsin L-like precursor 0.1017 0.1982 0.1981
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Leishmania major cysteine peptidase A (CPA) 0.1449 0.2852 0.6768
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0143 0.0143
Onchocerca volvulus 0.0046 0.0025 0.0032
Echinococcus multilocularis proteasome subunit alpha type 6 0.004 0.0013 0.0013
Toxoplasma gondii EF hand domain-containing protein 0.023 0.0397 0.0938
Entamoeba histolytica calpain large subunit domain III containing protein 0.1019 0.1985 0.6959
Trypanosoma cruzi histone deacetylase, putative 0.0104 0.0143 0.0141
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0035 0.0116
Mycobacterium ulcerans zinc metalloprotease 0.0099 0.0132 0.0709
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Giardia lamblia 20S proteasome alpha subunit 2 0.004 0.0013 0.0033
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4075 0.8144 0.8144
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Giardia lamblia Cathepsin L-like protease 0.0384 0.0706 0.1968
Onchocerca volvulus 0.0046 0.0025 0.0032
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0223 0.0223
Trypanosoma cruzi cysteine peptidase, putative 0.1505 0.2964 0.2963
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Trypanosoma brucei oligopeptidase b 0.0896 0.1739 0.4125
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Plasmodium vivax cysteine repeat modular protein 1, putative 0.007 0.0075 0.0256
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Echinococcus granulosus glycogen phosphorylase 0.0117 0.0169 0.0169
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0147 0.023 0.023
Plasmodium falciparum plasmepsin X 0.0297 0.0532 0.1861
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.014 0.0214 0.0212
Echinococcus granulosus cathepsin L 0.0816 0.1576 0.1576
Leishmania major hypothetical protein, conserved 0.0234 0.0405 0.0957
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0214 0.0504
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0384 0.0706 0.2471
Entamoeba histolytica cysteine proteinase 1, putative 0.0816 0.1576 0.5523
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0093 0.012 0.033
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.004 0.0013 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0064 0.0061 0.0061
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.004 0.0013 0.0023
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1073 0.2094 0.2093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Onchocerca volvulus Peroxidase homolog 0.0281 0.0499 0.1026
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0384 0.0706 0.0706
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0013 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Loa Loa (eye worm) hypothetical protein 0.01 0.0135 0.0133
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0022
Trypanosoma cruzi histone deacetylase, putative 0.0104 0.0143 0.0141
Echinococcus granulosus centrin 2 0.023 0.0397 0.0397
Schistosoma mansoni memapsin-2 (A01 family) 0.0532 0.1004 0.1004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1449 0.2852 0.7966
Plasmodium vivax proteasome subunit alpha type-1, putative 0.004 0.0013 0.0041
Leishmania major calmodulin-like protein 0.023 0.0397 0.0938
Echinococcus granulosus proteasome subunit beta type 6 0.004 0.0013 0.0013
Leishmania major i/6 autoantigen-like protein 0.023 0.0397 0.0938
Plasmodium vivax histone deacetylase, putative 0.0045 0.0023 0.0075
Brugia malayi Integrin alpha pat-2 precursor 0.0185 0.0305 0.0303
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0258 0.0452 0.0452
Onchocerca volvulus 0.0054 0.0042 0.0069
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0397 0.1104
Loa Loa (eye worm) hypothetical protein 0.0285 0.0508 0.0506
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Toxoplasma gondii cathepsin B 0.181 0.358 0.8497
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0009 0.0027
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Echinococcus multilocularis expressed protein 0.0441 0.082 0.082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Onchocerca volvulus 0.0049 0.0031 0.0046
Entamoeba histolytica calmodulin, putative 0.023 0.0397 0.1386
Brugia malayi Serine protease Z688.6 precursor 0.0064 0.0061 0.0059
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0012 0.0011
Giardia lamblia Glycogen phosphorylase 0.0117 0.0169 0.0466
Plasmodium falciparum metacaspase-like protein 0.014 0.0214 0.0745
Entamoeba histolytica glycogenphosphorylase, putative 0.0051 0.0035 0.0116
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Toxoplasma gondii subtilisin SUB12 0.0046 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1449 0.2852 1
Plasmodium vivax aspartyl protease, putative 0.0297 0.0532 0.1861
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Mycobacterium leprae Conserved hypothetical protein 0.0443 0.0824 0.4712
Echinococcus multilocularis histone deacetylase 0.0104 0.0143 0.0143
Echinococcus granulosus cathepsin l cysteine peptidase 0.1449 0.2852 0.2852
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.014 0.0214 0.0214
Trypanosoma cruzi I/6 autoantigen, putative 0.023 0.0397 0.0395
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0896 0.1739 0.1737
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0384 0.0706 0.1968
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Toxoplasma gondii preprocathepsin c precursor, putative 0.0384 0.0706 0.1672
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0421 0.0781 0.1851
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.004 0.0013 0.0041
Schistosoma mansoni calmodulin related calcium binding protein 0.023 0.0397 0.0397
Entamoeba histolytica cysteine proteinase 2 0.0816 0.1576 0.5523
Echinococcus granulosus cysteine protease 0.0816 0.1576 0.1576
Echinococcus multilocularis enteropeptidase 0.0181 0.0298 0.0298
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.009 0.0114 0.0395
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Loa Loa (eye worm) proteasome subunit beta type 3 0.004 0.0013 0.0012
Schistosoma mansoni calpain C (C02 family) 0.144 0.2834 0.2834
Mycobacterium ulcerans putative transglutaminase-like protein 0.0443 0.0824 0.4712
Plasmodium vivax proteasome subunit alpha type-6, putative 0.004 0.0013 0.0041
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.004 0.0013 0.0028
Echinococcus granulosus Mastin 0.0181 0.0298 0.0298
Loa Loa (eye worm) blistered cuticle protein 3 0.0281 0.0499 0.0497
Echinococcus granulosus integrin beta 2 0.028 0.0497 0.0497
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0384 0.0706 0.1968
Plasmodium falciparum serine repeat antigen 9 0.0384 0.0706 0.2471
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.0135 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Plasmodium falciparum proteasome subunit beta type-3, putative 0.004 0.0013 0.0041
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Brugia malayi cathepsin Z-like cysteine proteinase 0.0384 0.0706 0.0704
Plasmodium falciparum proteasome subunit beta type-4 0.004 0.0013 0.0041
Toxoplasma gondii ABC1 family protein 0.0038 0.0009 0.0018
Brugia malayi Protein kinase domain containing protein 0.007 0.0075 0.0073
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Echinococcus granulosus inhibitor of apoptosis protein 0.0191 0.0318 0.0318
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0299 0.0536 0.1493
Onchocerca volvulus Prolyl endopeptidase homolog 0.2125 0.4213 0.8815
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0096 0.0126 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0816 0.1576 0.3738
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0009 0.0008
Schistosoma mansoni cathepsin s 0.0432 0.0803 0.0803
Onchocerca volvulus 0.023 0.0397 0.0812
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0223 0.0222
Brugia malayi NAD-dependent deacetylase SIRT1 0.0285 0.0508 0.0506
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Echinococcus granulosus Transglutaminase 0.0443 0.0824 0.0824
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Loa Loa (eye worm) hypothetical protein 0.2405 0.4778 0.4778
Loa Loa (eye worm) aspartyl protease 6 0.0054 0.0042 0.0041
Onchocerca volvulus 0.0046 0.0025 0.0032
Echinococcus granulosus acylamino acid releasing enzyme 0.0299 0.0536 0.0536
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.004 0.0013 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0135 0.0135
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0135 0.0316
Echinococcus multilocularis Transglutaminase 0.0443 0.0824 0.0824
Brugia malayi EF hand family protein 0.0234 0.0405 0.0403
Toxoplasma gondii proteasome subunit alpha type, putative 0.004 0.0013 0.0028
Echinococcus granulosus proteasome prosome macropain 0.0248 0.0432 0.0432
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0896 0.1739 0.1737
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0248 0.0432 0.1509
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Plasmodium vivax proteasome subunit beta type-5, putative 0.0248 0.0432 0.1509
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0577 0.1094 0.2594
Echinococcus multilocularis GPI anchor transamidase 0.0034 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0177 0.0289 0.0289
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Brugia malayi proteasome subunit alpha type 4 0.004 0.0013 0.0012
Echinococcus granulosus dnaJ subfamily B 0.045 0.0839 0.0839
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.004 0.0013 0.0041
Onchocerca volvulus 0.1017 0.1982 0.4137
Loa Loa (eye worm) TK/ROR protein kinase 0.007 0.0075 0.0073
Brugia malayi prolyl oligopeptidase family protein 0.0299 0.0536 0.0534
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Trypanosoma brucei antigen, putative 0.144 0.2834 0.6725
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Schistosoma mansoni cellular tumor antigen P53 0.0058 0.005 0.005
Entamoeba histolytica grainin 2 0.0238 0.0411 0.1438
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0054 0.0042 0.0041
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Brugia malayi hypothetical protein 0.0281 0.0499 0.0497
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0064 0.0061 0.0061
Entamoeba histolytica proteasome subunit beta type 3, putative 0.004 0.0013 0.0041
Echinococcus multilocularis chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0012 0.0025
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Brugia malayi hypothetical protein 0.0277 0.0491 0.049
Schistosoma mansoni chromatin regulatory protein sir2 0.0066 0.0066 0.0066
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trypanosoma cruzi caltractin, putative 0.023 0.0397 0.0395
Brugia malayi Kelch motif family protein 0.0057 0.0049 0.0047
Giardia lamblia Hypothetical protein 0.0258 0.0452 0.1259
Schistosoma mansoni mitochondrial solute carrier 0.023 0.0397 0.0397
Brugia malayi gamma-secretase subunit aph-1 0.027 0.0477 0.0476
Giardia lamblia 20S proteasome alpha subunit 3 0.004 0.0013 0.0033
Toxoplasma gondii histone deacetylase SIR2 0.0066 0.0066 0.0154
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Trichomonas vaginalis centrin, putative 0.023 0.0397 0.1104
Trichomonas vaginalis calcium binding protein, putative 0.023 0.0397 0.1104
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0054 0.0042 0.0097
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0896 0.1739 0.4125
Brugia malayi Histone deacetylase 1 0.0093 0.012 0.0118
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Plasmodium falciparum peptidase, putative 0.0299 0.0536 0.1874
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0258 0.0452 0.1581
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.0013 0.0028
Schistosoma mansoni caspase-3 (C14 family) 0.0426 0.0791 0.0791
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trypanosoma cruzi cysteine proteinase, putative 0.0816 0.1576 0.1575
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Trichomonas vaginalis calcium binding protein, putative 0.023 0.0397 0.1104
Toxoplasma gondii EFHC1, putative 0.023 0.0397 0.0938
Loa Loa (eye worm) hypothetical protein 0.0102 0.0138 0.0136
Echinococcus granulosus EF hand domain containing family member A2 0.0234 0.0405 0.0405
Toxoplasma gondii exonuclease III APE 0.004 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0277 0.0491 0.049
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0191 0.0318 0.0316
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Loa Loa (eye worm) hypothetical protein 0.0182 0.03 0.0298
Loa Loa (eye worm) hypothetical protein 0.0432 0.0803 0.0801
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0384 0.0706 0.0704
Trypanosoma brucei calpain, putative 0.0421 0.0781 0.1851
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Loa Loa (eye worm) peptidase family M13 containing protein 0.0073 0.008 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0384 0.0706 0.1968
Giardia lamblia Histone deacetylase 0.0093 0.012 0.033
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0181 0.0298 0.0298
Echinococcus granulosus cathepsin L cysteine protease 0.0816 0.1576 0.1576
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Onchocerca volvulus Deterin homolog 0.0191 0.0318 0.0647
Schistosoma mansoni hypothetical protein 0.007 0.0075 0.0075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Echinococcus multilocularis calpain 5 0.144 0.2834 0.2834
Plasmodium falciparum proteasome subunit beta type-5 0.0248 0.0432 0.1509
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Schistosoma mansoni hypothetical protein 0.023 0.0397 0.0397
Echinococcus multilocularis EF hand domain containing family member A2 0.023 0.0397 0.0397
Plasmodium vivax hypothetical protein, conserved 0.014 0.0214 0.0745
Brugia malayi hypothetical protein 0.0054 0.0042 0.0041
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.0114 0.0114
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0191 0.0318 0.0316
Leishmania major hypothetical protein, conserved 0.023 0.0397 0.0938
Brugia malayi Pre-SET motif family protein 0.01 0.0135 0.0133
Echinococcus multilocularis caspase 3 0.0286 0.0509 0.0509
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.004 0.0013 0.0013
Trypanosoma brucei centrin-3 0.0238 0.0411 0.0973
Onchocerca volvulus 0.0054 0.0042 0.0069
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0181 0.0298 0.0298
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Brugia malayi EF hand family protein 0.023 0.0397 0.0395
Loa Loa (eye worm) cathepsin B 0.181 0.358 0.3579
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0191 0.0318 0.0318
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0285 0.0508 0.0508
Brugia malayi Cathepsin L-like precursor 0.1017 0.1982 0.1981
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0432 0.0803 0.0801
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0114 0.0315
Schistosoma mansoni hypothetical protein 0.0177 0.0289 0.0289
Brugia malayi aspartic protease BmAsp-2, identical 0.0054 0.0042 0.0041
Echinococcus multilocularis proteasome subunit alpha type 2 0.004 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0057 0.0049 0.0047
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.004 0.0013 0.0028
Plasmodium vivax unspecified product 0.0384 0.0706 0.2471
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Brugia malayi Papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Leishmania major proteasome alpha 3 subunit, putative 0.004 0.0013 0.0028
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Leishmania major C-8 sterol isomerase-like protein 0.037 0.0678 0.1605
Onchocerca volvulus 0.0046 0.0025 0.0032
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0248 0.0432 0.043
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.004 0.0013 0.0041
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Giardia lamblia Proteasome subunit beta type 7 precursor 0.004 0.0013 0.0033
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0093 0.012 0.033
Trichomonas vaginalis calcium binding protein, putative 0.023 0.0397 0.1104
Loa Loa (eye worm) histone deacetylase 7A 0.0104 0.0143 0.0141
Brugia malayi ERG2 and Sigma1 receptor like protein 0.037 0.0678 0.0676
Trypanosoma brucei metacaspase 0.014 0.0214 0.0504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0426 0.0791 0.0791
Brugia malayi proteasome subunit alpha type 1 0.004 0.0013 0.0012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0066 0.0066 0.0064
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Trypanosoma brucei SIR2-like protein 4, putative 0.0066 0.0066 0.0154
Trypanosoma brucei mitochondrial calcium uptake 1 0.023 0.0397 0.0938
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0064 0.0061 0.0166
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4075 0.8144 0.8144
Loa Loa (eye worm) prolyl oligopeptidase 0.1062 0.2073 0.2071
Echinococcus multilocularis calmodulin 0.023 0.0397 0.0397
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0384 0.0706 0.1968
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.144 0.2834 0.6725
Onchocerca volvulus Glycogen phosphorylase homolog 0.0117 0.0169 0.0334
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0299 0.0536 0.1874
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.181 0.358 0.8497
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0384 0.0706 0.0706
Onchocerca volvulus 0.0234 0.0405 0.0829
Echinococcus granulosus caspase 3 0.0286 0.0509 0.0509
Echinococcus granulosus calumenin 0.0234 0.0405 0.0405
Loa Loa (eye worm) cysteine protease 0.1449 0.2852 0.2851
Onchocerca volvulus 0.0384 0.0706 0.1461
Trypanosoma cruzi oligopeptidase b 0.0896 0.1739 0.1737
Mycobacterium ulcerans hypothetical protein 0.0181 0.0298 0.1668
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Mycobacterium ulcerans Sir2-like regulatory protein 0.0066 0.0066 0.0329
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4997 1 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0443 0.0824 0.2263
Onchocerca volvulus 0.007 0.0075 0.0137
Echinococcus multilocularis proteasome subunit beta type 7 0.004 0.0013 0.0013
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.027 0.0477 0.0476
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0054 0.0042 0.0042
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.004 0.0013 0.0013
Brugia malayi Pepsin A precursor 0.0054 0.0042 0.0041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.181 0.358 0.358
Brugia malayi Papain family cysteine protease containing protein 0.0816 0.1576 0.1575
Schistosoma mansoni chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1829 0.3619 0.3618
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Entamoeba histolytica calpain family cysteine protease, putative 0.0421 0.0781 0.2735
Leishmania major calcineurin B subunit, putative 0.023 0.0397 0.0938
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0299 0.0536 0.1268
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0219 0.0374 0.0372
Brugia malayi Peptidase family M13 containing protein 0.0099 0.0132 0.013
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1825 0.361 1
Schistosoma mansoni ap endonuclease 0.004 0.0012 0.0012
Echinococcus multilocularis calpain 7 (C02 family) 0.144 0.2834 0.2834
Schistosoma mansoni hypothetical protein 0.0443 0.0824 0.0824
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.004 0.0013 0.0041
Echinococcus granulosus integrin alpha 3 0.0142 0.0218 0.0218
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0896 0.1739 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Plasmodium vivax proteasome subunit beta type-6, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Schistosoma mansoni cathepsin S (C01 family) 0.0384 0.0706 0.0706
Plasmodium falciparum plasmepsin IV 0.0054 0.0042 0.0143
Echinococcus granulosus Proteasome subunit alpha beta 0.004 0.0013 0.0013
Trichomonas vaginalis glycogen phosphorylase, putative 0.0117 0.0169 0.0466
Entamoeba histolytica prolyl oligopeptidase family protein 0.0299 0.0536 0.1874
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0688 0.1319 0.1319
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Trypanosoma brucei Calpain-like protein 1.1 0.0421 0.0781 0.1851
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0384 0.0706 0.1968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1017 0.1982 0.5534
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1449 0.2852 0.2851
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0276 0.0488 0.0487
Echinococcus multilocularis glycoprotein Antigen 5 0.0181 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.0013 0.0012
Brugia malayi cathepsin F-like cysteine proteinase 0.0384 0.0706 0.0704
Giardia lamblia Hypothetical protein 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.007 0.0075 0.0073
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1449 0.2852 0.2852
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0384 0.0706 0.2471
Brugia malayi calpain 5 0.1019 0.1985 0.1984
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.0013 0.0012
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.0013 0.0028
Schistosoma mansoni calmodulin 0.023 0.0397 0.0397
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0114 0.0315
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0421 0.0781 0.1851
Plasmodium vivax proteasome subunit alpha type-3, putative 0.004 0.0013 0.0041
Plasmodium falciparum plasmepsin VIII, putative 0.0054 0.0042 0.0143
Loa Loa (eye worm) hypothetical protein 0.0099 0.0132 0.013
Brugia malayi calpain 7 0.144 0.2834 0.2833
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Loa Loa (eye worm) PAS-3 protein 0.004 0.0013 0.0012
Toxoplasma gondii microneme protein, putative 0.0046 0.0025 0.0054
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Leishmania major histone deacetylase, putative 0.0093 0.012 0.0281
Onchocerca volvulus 0.0064 0.0061 0.0108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0248 0.0432 0.1173
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Plasmodium falciparum serine repeat antigen 1 0.0384 0.0706 0.2471
Loa Loa (eye worm) hypothetical protein 0.0421 0.0781 0.078
Plasmodium vivax vivapain-2 0.1449 0.2852 1
Leishmania major phospholipase c-like protein 0.023 0.0397 0.0938
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0258 0.0452 0.1259
Trypanosoma brucei metacaspase 5, putative 0.014 0.0214 0.0504
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0299 0.0536 0.1874
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Trypanosoma cruzi cysteine peptidase, putative 0.1505 0.2964 0.2963
Echinococcus multilocularis prolyl endopeptidase 0.2125 0.4213 0.4213
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1449 0.2852 0.7966
Loa Loa (eye worm) hypothetical protein 0.1017 0.1982 0.1981
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.4075 0.8144 0.8144
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Onchocerca volvulus Histone deacetylase 10 homolog 0.0045 0.0023 0.0028
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1062 0.2073 0.2073
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.0432 0.043
Schistosoma mansoni histone deacetylase hda2 0.0111 0.0156 0.0156
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.023 0.0397 0.1104
Loa Loa (eye worm) proteasome subunit alpha type 1 0.004 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.0013 0.0041
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0258 0.0452 0.107
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Trypanosoma brucei proteasome beta 7 subunit 0.004 0.0013 0.0028
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0066 0.0066 0.0065
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.004 0.0013 0.0028
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.004 0.0013 0.0028
Schistosoma mansoni cathepsin F (C01 family) 0.1017 0.1982 0.1982
Loa Loa (eye worm) hypothetical protein 0.2826 0.5627 0.5626
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3845 0.768 0.768
Echinococcus granulosus histone deacetylase 3 0.0093 0.012 0.012
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.023 0.0397 0.0395
Toxoplasma gondii proteasome subunit beta type 2, putative 0.009 0.0114 0.0267
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.0217 0.1198
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.0135 0.0135
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0099 0.0132 0.0132
Trypanosoma cruzi cruzipain precursor, putative 0.0432 0.0803 0.0801
Schistosoma mansoni histone deacetylase 4 5 0.0104 0.0143 0.0143
Plasmodium vivax calpain, putative 0.144 0.2834 0.9935
Giardia lamblia Cathepsin L-like protease 0.0384 0.0706 0.1968
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0012 0.0011
Chlamydia trachomatis glycogen phosphorylase 0.0117 0.0169 0.5
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0142 0.0219 0.0219
Loa Loa (eye worm) integrin alpha pat-2 0.0285 0.0506 0.0505
Plasmodium falciparum plasmepsin VII 0.0054 0.0042 0.0143
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0064 0.0061 0.0166
Schistosoma mansoni cathepsin D (A01 family) 0.0338 0.0614 0.0614
Leishmania major sir2-family protein-like protein 0.0066 0.0066 0.0154
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.004 0.0013 0.0013
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Schistosoma mansoni hypothetical protein 0.0181 0.0298 0.0298
Echinococcus multilocularis gamma secretase subunit aph 1 0.027 0.0477 0.0477
Loa Loa (eye worm) calmodulin-like protein 0.023 0.0397 0.0395
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.023 0.0397 0.1386
Leishmania major histone deacetylase, putative 0.0104 0.0143 0.0335
Echinococcus multilocularis neurocalcin 0.023 0.0397 0.0397
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Toxoplasma gondii peptidase family M13 protein 0.0099 0.0132 0.031
Loa Loa (eye worm) proteasome subunit alpha type 3 0.004 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0041
Schistosoma mansoni calpain-7 (C02 family) 0.1443 0.284 0.284
Giardia lamblia Serine peptidase, putative 0.0064 0.0061 0.0166
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Trypanosoma brucei proteasome alpha 7 subunit 0.004 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.004 0.0013 0.0013
Leishmania major proteasome beta 5 subunit, putative 0.0248 0.0432 0.1021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Mycobacterium ulcerans transglutaminase family protein 0.0443 0.0824 0.4712
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Echinococcus granulosus histone deacetylase 1 0.0093 0.012 0.012
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Echinococcus multilocularis tissue type plasminogen activator 0.007 0.0075 0.0075
Mycobacterium tuberculosis Long conserved protein 0.0443 0.0824 0.2263
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0816 0.1576 0.1576
Mycobacterium ulcerans hypothetical protein 0.0443 0.0824 0.4712
Echinococcus granulosus proteasome subunit alpha type 6 0.004 0.0013 0.0013
Brugia malayi Kringle domain containing protein 0.007 0.0075 0.0073
Echinococcus multilocularis integrin alpha ps 0.0083 0.01 0.01
Plasmodium vivax unspecified product 0.0816 0.1576 0.5523
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0384 0.0706 0.1968
Echinococcus multilocularis caspase 0.0426 0.0791 0.0791
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0051 0.0035 0.0146
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.004 0.0013 0.0028
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Echinococcus granulosus neuronal calcium sensor 0.023 0.0397 0.0397
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.004 0.0013 0.0028
Trypanosoma cruzi cysteine proteinase, putative 0.0816 0.1576 0.1575
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Onchocerca volvulus 0.0181 0.0298 0.0605
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0248 0.0432 0.0432
Brugia malayi proteasome subunit beta type 3 0.004 0.0013 0.0012
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.004 0.0013 0.0013
Trichomonas vaginalis set domain proteins, putative 0.0792 0.1528 0.4264
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.004 0.0013 0.0041
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0066 0.0066 0.0227
Giardia lamblia Proteasome subunit beta type 3 0.004 0.0013 0.0033
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.1185 0.2319 0.2319
Plasmodium vivax SET domain protein, putative 0.01 0.0135 0.0468
Onchocerca volvulus Notchless protein homolog 0.004 0.0013 0.0008
Echinococcus granulosus gamma secretase subunit aph 1 0.027 0.0477 0.0477
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0013 0.0028
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0012 0.003
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0142 0.0219 0.0763
Loa Loa (eye worm) calpain family protein 1 0.2826 0.5627 0.5626
Brugia malayi beta-lactamase family protein 0.0038 0.0009 0.0008
Trypanosoma brucei cysteine peptidase C (CPC) 0.181 0.358 0.8497
Trypanosoma brucei Calpain-like protein CALP1.3 0.0421 0.0781 0.1851
Echinococcus granulosus subfamily T1A non peptidase ue 0.004 0.0013 0.0013

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.003 uM In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa ChEMBL. 11392540
IC50 (binding) = 0.003 uM In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa ChEMBL. 11392540
IC50 (functional) = 0.179 uM In vitro ability to inhibit the aggregation of ADP-stimulated human platelets ChEMBL. 11392540
IC50 (functional) = 0.179 uM In vitro ability to inhibit the aggregation of ADP-stimulated human platelets ChEMBL. 11392540

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 11392540

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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