Detailed information for compound 313232

Basic information

Technical information
  • TDR Targets ID: 313232
  • Name: 4-[(Z)-(5-bromo-2,3-dihydroinden-1-ylidene)me thyl]pyridine
  • MW: 286.166 | Formula: C15H12BrN
  • H donors: 0 H acceptors: 1 LogP: 3.73 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccc2c(c1)CC/C/2=C/c1ccncc1
  • InChi: 1S/C15H12BrN/c16-14-3-4-15-12(1-2-13(15)10-14)9-11-5-7-17-8-6-11/h3-10H,1-2H2/b12-9-
  • InChiKey: MNQUPNOEJZVKRD-XFXZXTDPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[(Z)-(5-bromoindan-1-ylidene)methyl]pyridine
  • 4-[(Z)-(5-bromo-1-indanylidene)methyl]pyridine
  • (4-Pyridylmethylene)indane 10b

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 11, subfamily B, polypeptide 2 Starlite/ChEMBL References
Homo sapiens cytochrome P450, family 19, subfamily A, polypeptide 1 Starlite/ChEMBL References
Homo sapiens cytochrome P450, family 11, subfamily B, polypeptide 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum Os02g0824100 protein, related Get druggable targets OG5_134469 All targets in OG5_134469
Toxoplasma gondii cytochrome p450 superfamily protein Get druggable targets OG5_134469 All targets in OG5_134469
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi cytochrome P450, putative cytochrome P450, family 19, subfamily A, polypeptide 1 503 aa 425 aa 18.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0031 0.032
Loa Loa (eye worm) hypothetical protein 0.0388 0.0527 0.0527
Echinococcus multilocularis caspase 0.0114 0.014 0.014
Echinococcus granulosus General substrate transporter 0.0088 0.0104 0.0104
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0316 0.0426 0.0426
Plasmodium falciparum plasmepsin VII 0.0019 0.0006 0.0033
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1711 0.2393 0.2393
Schistosoma mansoni myosin light chain 0.0027 0.0018 0.0018
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0031 0.0088
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Schistosoma mansoni calmodulin related calcium binding protein 0.0316 0.0426 0.0426
Loa Loa (eye worm) prolyl oligopeptidase 0.0536 0.0736 0.0736
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0024 0.0024
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.014 0.0178 0.0509
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0023 0.0092
Onchocerca volvulus 0.0096 0.0115 0.0242
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0042 0.0039 0.017
Trichomonas vaginalis calcium binding protein, putative 0.0316 0.0426 0.1219
Toxoplasma gondii kringle domain-containing protein 0.0045 0.0044 0.0125
Giardia lamblia Serine peptidase, putative 0.0021 0.001 0.0027
Schistosoma mansoni calpain (C02 family) 0.201 0.2815 0.2815
Loa Loa (eye worm) hypothetical protein 0.007 0.0078 0.0078
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Echinococcus multilocularis acylamino acid releasing enzyme 0.0205 0.0269 0.0269
Onchocerca volvulus 0.0026 0.0017 0.0036
Brugia malayi proteasome subunit alpha type 2 0.0018 0.0005 0.0005
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.2489 0.3491 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Brugia malayi cathepsin Z-like cysteine proteinase 0.0423 0.0577 0.0577
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0115 0.0115
Echinococcus multilocularis proteasome (prosome, macropain) 0.0091 0.0107 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0011 0.0023
Brugia malayi cytochrome P450 0.0028 0.002 0.002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0024 0.0024
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0018 0.0005 0.0014
Schistosoma mansoni centrin 0.0316 0.0426 0.0426
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Schistosoma mansoni cpg binding protein 0.0058 0.0062 0.0062
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0005 0.0005
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0423 0.0577 0.2866
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0321 0.0432 0.0432
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.058 0.0798 0.0798
Trypanosoma brucei I/6 autoantigen 0.0316 0.0426 0.1219
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0021 0.006
Trypanosoma brucei antigen, putative 0.201 0.2815 0.8064
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0321 0.0432 0.0432
Echinococcus multilocularis caspase 2 0.0177 0.0229 0.0229
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0011 0.0011
Plasmodium vivax proteasome subunit beta type-5, putative 0.0091 0.0107 0.0382
Echinococcus multilocularis transmembrane protease serine 3 0.01 0.0121 0.0121
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.01 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.0018
Brugia malayi proteasome subunit beta type 2 0.0044 0.0041 0.0041
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Schistosoma mansoni neuronal calcium sensor 0.0316 0.0426 0.0426
Loa Loa (eye worm) cysteine protease 0.1381 0.1927 0.1927
Leishmania major proteasome beta-1 subunit, putative 0.0018 0.0005 0.0014
Brugia malayi Papain family cysteine protease containing protein 0.0423 0.0577 0.0577
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0021 0.006
Schistosoma mansoni cathepsin F (C01 family) 0.1381 0.1927 0.1927
Leishmania major proteasome alpha 7 subunit, putative 0.0018 0.0005 0.0014
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0018 0.0005 0.0005
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.001 0.0024
Plasmodium vivax aspartyl protease, putative 0.0019 0.0006 0.0022
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.001 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0011 0.0011
Plasmodium vivax plasmepsin V, putative 0.0019 0.0006 0.0022
Brugia malayi hypothetical protein 0.0092 0.011 0.011
Echinococcus granulosus proteasome subunit beta type 6 0.0018 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0423 0.0577 0.1652
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0018 0.0005 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0011 0.0011
Leishmania major calcineurin B subunit, putative 0.0316 0.0426 0.1219
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0423 0.0577 0.2049
Brugia malayi MH2 domain containing protein 0.0123 0.0153 0.0153
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0005 0.0005
Echinococcus multilocularis neuronal calcium sensor 0.0316 0.0426 0.0426
Echinococcus multilocularis 0.0028 0.002 0.002
Trypanosoma cruzi Aph-1 protein, putative 0.0109 0.0134 0.0134
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Entamoeba histolytica cysteine proteinase 2 0.0811 0.1124 0.561
Onchocerca volvulus 0.1381 0.1927 0.4064
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0018 0.0005 0.0005
Toxoplasma gondii calcium binding egf domain-containing protein 0.0015 0.0001 0.0003
Plasmodium falciparum plasmepsin VI 0.0019 0.0006 0.0033
Entamoeba histolytica prolyl oligopeptidase family protein 0.0205 0.0269 0.1323
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0313 0.0422 0.089
Brugia malayi Cathepsin L-like precursor 0.0993 0.138 0.138
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0423 0.0577 0.1652
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0018 0.0005 0.0014
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.7103 1 1
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0039 0.0111
Loa Loa (eye worm) hypothetical protein 0.1381 0.1927 0.1927
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0024 0.0024
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0043 0.004 0.004
Plasmodium falciparum protein kinase 7 0.029 0.0389 0.202
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Brugia malayi Fibulin-1 precursor 0.0015 0.0001 0.0001
Toxoplasma gondii cathepsin CPL 0.1381 0.1927 0.5521
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0116 0.0116
Brugia malayi Sugar transporter family protein 0.0103 0.0124 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.004 0.0115
Leishmania major cathepsin L-like protease 0.1381 0.1927 0.5521
Trichomonas vaginalis conserved hypothetical protein 0.058 0.0798 0.2285
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0318 0.0429 0.1228
Brugia malayi prolyl oligopeptidase family protein 0.0536 0.0736 0.0736
Echinococcus granulosus Mastin 0.01 0.0121 0.0121
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0811 0.1124 0.3221
Brugia malayi Blistered cuticle protein 3 0.0104 0.0126 0.0126
Brugia malayi Flap endonuclease-1 0.0025 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0316 0.0426 0.1219
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0031 0.0131
Entamoeba histolytica cysteine protease, putative 0.0423 0.0577 0.2866
Brugia malayi Proteasome A-type and B-type family protein 0.0091 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0388 0.0527 0.0527
Leishmania major proteasome beta 7 subunit, putative 0.0018 0.0005 0.0014
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0018 0.0005 0.0005
Brugia malayi Pepsin A precursor 0.0019 0.0006 0.0006
Echinococcus granulosus caspase 3 0.0071 0.0079 0.0079
Plasmodium vivax metacaspase 1, putative 0.0043 0.004 0.0143
Trypanosoma cruzi calpain cysteine peptidase, putative 0.201 0.2815 0.2815
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0011 0.0011
Onchocerca volvulus 0.1381 0.1927 0.4064
Plasmodium vivax proteasome subunit beta type-7, putative 0.0018 0.0005 0.0017
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0007 0.0021
Schistosoma mansoni neuronal calcium sensor 0.0316 0.0426 0.0426
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0011 0.0011
Plasmodium falciparum cysteine repeat modular protein 1 0.0045 0.0044 0.0226
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0011 0.0011
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0031 0.0088
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0025 0.0121
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0011 0.0011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.058 0.0798 0.0798
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.2815
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0019 0.0006 0.0018
Onchocerca volvulus 0.01 0.0121 0.0256
Leishmania major cytochrome p450-like protein 0.0028 0.002 0.0056
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0021 0.001 0.001
Echinococcus granulosus intermediate filament protein 0.0026 0.0017 0.0017
Trypanosoma cruzi metacaspase, putative 0.0043 0.004 0.004
Leishmania major proteasome alpha 3 subunit, putative 0.0018 0.0005 0.0014
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0605 0.0833 0.2386
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.002 0.0203
Echinococcus multilocularis EF hand domain containing family member A2 0.0321 0.0432 0.0432
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0039 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0269 0.0269
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0023 0.0191
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0018 0.0005 0.0014
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0039 0.0039
Echinococcus multilocularis programmed cell death protein 6 0.0032 0.0024 0.0024
Schistosoma mansoni protein kinase 0.0032 0.0024 0.0024
Echinococcus multilocularis inhibitor of apoptosis protein 0.0177 0.023 0.023
Schistosoma mansoni hypothetical protein 0.0053 0.0055 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0115 0.0115
Schistosoma mansoni caspase-7 (C14 family) 0.0177 0.0229 0.0229
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Brugia malayi Cathepsin L-like precursor 0.0993 0.138 0.138
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0018 0.0005 0.0005
Brugia malayi calpain family protein 1 0.5386 0.7578 0.7578
Echinococcus granulosus cathepsin l1 0.1381 0.1927 0.1927
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0031 0.0088
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0035 0.0101
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0018 0.0005 0.0017
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0013 0.0069
Trypanosoma cruzi metacaspase, putative 0.0043 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0423 0.0577 0.0577
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0027 0.0018 0.0037
Trypanosoma brucei calpain, putative 0.058 0.0798 0.2285
Onchocerca volvulus Cathepsin L homolog 0.1381 0.1927 0.4064
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1381 0.1927 0.1927
Echinococcus multilocularis gamma secretase subunit aph 1 0.028 0.0375 0.0375
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0013 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.201 0.2815 0.2815
Entamoeba histolytica grainin 2 0.0343 0.0464 0.2299
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Brugia malayi proteasome subunit alpha type 3 0.0018 0.0005 0.0005
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0039 0.0039
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0153 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Echinococcus granulosus microtubule associated protein 2 0.2185 0.3062 0.3062
Mycobacterium leprae Conserved hypothetical protein 0.0174 0.0226 0.2305
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0423 0.0577 0.2049
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0012 0.0012
Brugia malayi Cathepsin L-like precursor 0.1381 0.1927 0.1927
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0039 0.0039
Echinococcus multilocularis neurocalcin 0.0316 0.0426 0.0426
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0044 0.0044
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1506 0.2104 1
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0013 0.0038
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.004 0.004
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.01 0.0121 0.0121
Trypanosoma cruzi cysteine peptidase, putative 0.0388 0.0527 0.0527
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0047 0.0047 0.0483
Brugia malayi nuclear hormone receptor 0.0022 0.0011 0.0011
Loa Loa (eye worm) fibroinase 0.1381 0.1927 0.1927
Echinococcus multilocularis tissue type plasminogen activator 0.0045 0.0044 0.0044
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0423 0.0577 0.2049
Echinococcus multilocularis calbindin 32 0.0321 0.0432 0.0432
Onchocerca volvulus 0.0134 0.0169 0.0356
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Toxoplasma gondii hypothetical protein 0.0029 0.0021 0.006
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0039 0.0039
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.004 0.0115
Brugia malayi 20S proteasome alpha5 subunit 0.0018 0.0005 0.0005
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0021 0.0021
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0047 0.0047
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0013 0.0013
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0044 0.0041 0.0041
Plasmodium falciparum serine repeat antigen 1 0.0423 0.0577 0.2992
Brugia malayi Eukaryotic aspartyl protease family protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0094 0.0112 0.0112
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0018 0.0005 0.0005
Echinococcus multilocularis General substrate transporter 0.0088 0.0104 0.0104
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0018 0.0005 0.0014
Trypanosoma brucei Calpain-like protein 1.2 0.058 0.0798 0.2285
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0423 0.0577 0.2049
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0113 0.0325
Trypanosoma cruzi hexose transporter 0.0032 0.0025 0.0025
Loa Loa (eye worm) proteasome subunit beta type 3 0.0018 0.0005 0.0005
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0126 0.0126
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0013 0.0063
Onchocerca volvulus 0.0029 0.0021 0.0044
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0031 1
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0027 0.0018 0.0063
Echinococcus multilocularis Myosin regulatory light chain 0.0027 0.0018 0.0018
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.8064
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0113 0.0113
Mycobacterium ulcerans hypothetical protein 0.01 0.0121 0.1258
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0078 0.0078
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0035 0.0101
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0091 0.0107 0.0308
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0021 0.0021
Echinococcus multilocularis GPI anchor transamidase 0.014 0.0178 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0423 0.0577 0.1652
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.008
Leishmania major calmodulin-like protein 0.0316 0.0426 0.1219
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0168 0.0797
Schistosoma mansoni hypothetical protein 0.0028 0.002 0.002
Schistosoma mansoni inhibitor of apoptosis protein 0.0177 0.023 0.023
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0012 0.0042
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0018 0.0005 0.0005
Toxoplasma gondii calcium binding egf domain-containing protein 0.0015 0.0001 0.0003
Echinococcus granulosus calbindin 32 0.0321 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Echinococcus granulosus Myosin regulatory light chain 0.0027 0.0018 0.0018
Brugia malayi Peptidase family M13 containing protein 0.0094 0.0112 0.0112
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0116 0.0116
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.058 0.0798 0.2285
Giardia lamblia Cathepsin B precursor 0.2489 0.3491 1
Schistosoma mansoni glucose transport protein 0.0103 0.0124 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0042 0.0042
Echinococcus multilocularis peroxidasin 0.0104 0.0126 0.0126
Echinococcus multilocularis fibrillin 1 0.0015 0.0001 0.0001
Trypanosoma brucei Metacaspase-4 0.0043 0.004 0.0115
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0025 0.007
Echinococcus granulosus prolyl endopeptidase 0.1711 0.2393 0.2393
Leishmania major hypothetical protein, conserved 0.0045 0.0044 0.0125
Leishmania major calmodulin-like protein 0.0316 0.0426 0.1219
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0423 0.0577 0.0577
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0007 0.0035
Giardia lamblia Cathepsin L precursor 0.0423 0.0577 0.1652
Schistosoma mansoni glucose transport protein 0.0103 0.0124 0.0124
Brugia malayi Calcium binding EGF domain containing protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Trypanosoma brucei cysteine peptidase C (CPC) 0.2489 0.3491 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.2815
Leishmania major cathepsin L-like protease 0.1381 0.1927 0.5521
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0011 0.0011
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.002 0.002
Trichomonas vaginalis calmodulin, putative 0.0343 0.0464 0.1328
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0039 0.0039
Echinococcus multilocularis expressed protein 0.0815 0.113 0.113
Giardia lamblia Alanyl dipeptidyl peptidase 0.0205 0.0269 0.077
Onchocerca volvulus Cathepsin L homolog 0.0423 0.0577 0.1216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0035 0.0168
Toxoplasma gondii subtilisin SUB12 0.0029 0.0021 0.006
Echinococcus multilocularis cathepsin b 0.7103 1 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.002 0.0093
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0013 0.0038
Onchocerca volvulus 0.1381 0.1927 0.4064
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0021 0.001 0.001
Entamoeba histolytica cysteine proteinase, putative 0.1381 0.1927 0.9634
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0018 0.0005 0.0014
Onchocerca volvulus Peroxidase homolog 0.0104 0.0126 0.0267
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.001 0.001
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Echinococcus granulosus acylamino acid releasing enzyme 0.0205 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Schistosoma mansoni caspase-3 (C14 family) 0.0114 0.014 0.014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0116 0.0116
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0094 0.0112 0.0534
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0318 0.0429 0.0429
Brugia malayi Peroxidasin 0.0104 0.0126 0.0126
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0024 0.0024
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0035 0.0101
Trichomonas vaginalis calmodulin, putative 0.0316 0.0426 0.1219
Toxoplasma gondii proteasome beta subunit 0.0018 0.0005 0.0014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0205 0.0269 0.0269
Mycobacterium ulcerans transglutaminase family protein 0.0174 0.0226 0.2343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Loa Loa (eye worm) hypothetical protein 0.0423 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Trichomonas vaginalis caltractin, putative 0.0027 0.0018 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0113 0.0113
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0091 0.0107 0.0308
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0205 0.0269 0.0269
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.0348 0.0348
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0018 0.0005 0.0005
Schistosoma mansoni neuronal calcium sensor 0.0316 0.0426 0.0426
Schistosoma mansoni cathepsin F (C01 family) 0.1381 0.1927 0.1927
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0113 0.0325
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.201 0.2815 0.2815
Echinococcus granulosus laminin 0.0015 0.0001 0.0001
Giardia lamblia Cathepsin B precursor 0.2489 0.3491 1
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0025 0.0025
Echinococcus multilocularis proteasome subunit beta type 7 0.0018 0.0005 0.0005
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0316 0.0426 0.2109
Trichomonas vaginalis calmodulin-2, putative 0.0316 0.0426 0.1219
Echinococcus granulosus tissue type plasminogen activator 0.0045 0.0044 0.0044
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0031 0.0031
Brugia malayi calcium-binding protein 0.0316 0.0426 0.0426
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0018 0.0005 0.0025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0116 0.0116
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0011 0.0011
Brugia malayi Thioredoxin family protein 0.0174 0.0226 0.0226
Toxoplasma gondii peptidase family M13 protein 0.0094 0.0112 0.0322
Giardia lamblia Cysteine protease 0.0423 0.0577 0.1652
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.028 0.0375 0.0375
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0012 0.0012
Onchocerca volvulus 0.0316 0.0426 0.0897
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0007 0.0034
Echinococcus multilocularis calpain A 0.5707 0.8031 0.8031
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0124 0.0124
Trypanosoma cruzi cysteine proteinase, putative 0.0811 0.1124 0.1124
Brugia malayi Serine carboxypeptidase S28 family protein 0.0021 0.001 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.1483 0.2072 0.2072
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0388 0.0527 0.0527
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Toxoplasma gondii hypothetical protein 0.0029 0.0021 0.006
Schistosoma mansoni calmodulin-related 0.0027 0.0018 0.0018
Plasmodium falciparum plasmepsin IV 0.0019 0.0006 0.0033
Entamoeba histolytica cysteine proteinase, putative 0.1381 0.1927 0.9634
Giardia lamblia Proteasome subunit beta type 2 0.0044 0.0041 0.0118
Trichomonas vaginalis calcium binding proteins, putative 0.0316 0.0426 0.1219
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Onchocerca volvulus 0.0027 0.0018 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0005 0.0014
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0177 0.023 0.023
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0011 0.0011
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0423 0.0577 0.2866
Echinococcus multilocularis Transglutaminase 0.0174 0.0226 0.0226
Toxoplasma gondii exonuclease III APE 0.002 0.0007 0.0021
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0012 0.0012
Entamoeba histolytica grainin 2 0.0027 0.0018 0.0065
Loa Loa (eye worm) hypothetical protein 0.0261 0.0348 0.0348
Entamoeba histolytica calmodulin, putative 0.0316 0.0426 0.2109
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0018 0.0005 0.0014
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0177 0.023 0.023
Onchocerca volvulus 0.0039 0.0035 0.0074
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0024 0.0127
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0039 0.0039
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0035 0.0366
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1381 0.1927 0.5521
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Echinococcus multilocularis tumor protein p63 0.0369 0.05 0.05
Trichomonas vaginalis calpain, putative 0.058 0.0798 0.2285
Echinococcus granulosus calpain A 0.5707 0.8031 0.8031
Schistosoma mansoni cytochrome P450 0.0028 0.002 0.002
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.002 0.0093
Onchocerca volvulus 0.0029 0.0021 0.0044
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.058 0.0798 0.2285
Loa Loa (eye worm) trypsin family protein 0.01 0.0121 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.2489 0.3491 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0012 0.0034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.201 0.2815 0.2815
Onchocerca volvulus 0.0321 0.0432 0.0911
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.007 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Onchocerca volvulus 0.0058 0.0062 0.013
Plasmodium vivax unspecified product 0.0388 0.0527 0.1873
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0015 0.0044
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0018 0.0005 0.0017
Echinococcus granulosus cathepsin l1 0.0993 0.138 0.138
Trichomonas vaginalis calpain, putative 0.058 0.0798 0.2285
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0013 0.0038
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0039 0.0039
Echinococcus multilocularis cathepsin b 0.7103 1 1
Entamoeba histolytica glycogenphosphorylase, putative 0.0048 0.0047 0.0213
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0423 0.0577 0.2049
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2489 0.3491 0.3491
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0012 0.0075
Onchocerca volvulus 0.0104 0.0126 0.0267
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0012 0.0124
Giardia lamblia 20S proteasome alpha subunit 5 0.0018 0.0005 0.0014
Schistosoma mansoni peroxidasin 0.0104 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0039 0.0039
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0035 0.0125
Echinococcus multilocularis glycoprotein Antigen 5 0.01 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0168 0.0168
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0045 0.0044 0.0155
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.0006 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0423 0.0577 0.1652
Giardia lamblia 20S proteasome alpha subunit 7 0.0018 0.0005 0.0014
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0039 0.0039
Trichomonas vaginalis centrin, putative 0.0027 0.0018 0.005
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0316 0.0426 0.0426
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0018 0.0005 0.0014
Plasmodium falciparum proteasome subunit beta type-1, putative 0.007 0.0079 0.0409
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0019 0.0006 0.0018
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0021 0.001 0.001
Echinococcus granulosus caspase 0.0114 0.014 0.014
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0394 0.0535 0.0535
Plasmodium falciparum serine repeat antigen 4 0.0423 0.0577 0.2992
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0018 0.0005 0.0005
Brugia malayi Neuronal calcium sensor family protein 1 0.0027 0.0018 0.0018
Trypanosoma brucei hypothetical protein 0.058 0.0798 0.2285
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0011 0.0011
Toxoplasma gondii EF hand domain-containing protein 0.0027 0.0018 0.005
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Toxoplasma gondii proteasome subunit beta type, putative 0.0091 0.0107 0.0308
Echinococcus multilocularis dnaJ subfamily B 0.0828 0.1148 0.1148
Onchocerca volvulus 0.1381 0.1927 0.4064
Leishmania major programmed cell death 6 protein-like protein 0.0316 0.0426 0.1219
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0031 0.0088
Trypanosoma cruzi oligopeptidase b 0.0698 0.0964 0.0964
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0012 0.0034
Plasmodium vivax aspartyl protease, putative 0.0019 0.0006 0.0022
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1095 0.1525 0.1525
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0124 0.0357
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.0124 0.0357
Trichomonas vaginalis centrin, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0011 0.0011
Brugia malayi programmed cell death protein 6 0.0316 0.0426 0.0426
Giardia lamblia 20S proteasome alpha subunit 6 0.0018 0.0005 0.0014
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.002 0.0093
Plasmodium falciparum serine repeat antigen 6 0.0423 0.0577 0.2992
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Toxoplasma gondii cytochrome p450 superfamily protein 0.0937 0.1302 0.373
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0168 0.0168
Mycobacterium ulcerans hypothetical protein 0.0174 0.0226 0.2343
Loa Loa (eye worm) cytochrome P450 family protein 0.007 0.0078 0.0078
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0017 0.0017
Entamoeba histolytica calmodulin, putative 0.0316 0.0426 0.2109
Entamoeba histolytica hypothetical protein 0.0042 0.0039 0.017
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0039 0.0039
Brugia malayi Proteasome subunit alpha type 1 0.0018 0.0005 0.0005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.01 0.0121 0.0121
Trichomonas vaginalis esterase, putative 0.0039 0.0035 0.0101
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0015 0.0044
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0017 0.0017
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.0113 0.0113
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0018 0.0005 0.0005
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0811 0.1124 0.1124
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0039 0.0111
Brugia malayi Cathepsin L-like precursor 0.1381 0.1927 0.1927
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.0348 0.0348
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.001 0.001
Trypanosoma brucei polo-like protein kinase 0.0095 0.0113 0.0325
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0018 0.0005 0.0025
Loa Loa (eye worm) ctsf protein 0.1381 0.1927 0.1927
Loa Loa (eye worm) programmed cell death protein 6 0.0321 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.008
Onchocerca volvulus 0.0316 0.0426 0.0897
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.003 0.0087
Trichomonas vaginalis calcineurin B subunit, putative 0.0316 0.0426 0.1219
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0423 0.0577 0.0577
Brugia malayi prolyl oligopeptidase family protein 0.0205 0.0269 0.0269
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0297 0.0399 0.0399
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0018 0.0005 0.0005
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0018 0.0005 0.0005
Echinococcus granulosus calmodulin 0.0316 0.0426 0.0426
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0035 0.0035
Leishmania major calpain protease-like protein 0.058 0.0798 0.2285
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0024 0.007
Onchocerca volvulus 0.0027 0.0018 0.0037
Echinococcus granulosus calpain 5 0.201 0.2815 0.2815
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Giardia lamblia Cathepsin L precursor 0.0423 0.0577 0.1652
Trypanosoma brucei metacaspase MCA3 0.0043 0.004 0.0115
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.0113 0.0113
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1381 0.1927 0.1927
Trypanosoma cruzi kinesin, putative 0.143 0.1997 0.1997
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0047 0.0047
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.002 0.0093
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0024 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Onchocerca volvulus 0.0029 0.0021 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Toxoplasma gondii troponin c, isotype gamma, putative 0.0316 0.0426 0.1219
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0018 0.0005 0.0005
Onchocerca volvulus 0.01 0.0121 0.0256
Mycobacterium tuberculosis Conserved protein 0.0039 0.0035 0.0168
Brugia malayi Papain family cysteine protease containing protein 0.0423 0.0577 0.0577
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0018 0.0018
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0044 0.0041 0.0213
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0018 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0023
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Echinococcus granulosus Transglutaminase 0.0174 0.0226 0.0226
Mycobacterium tuberculosis Conserved protein 0.0039 0.0035 0.0168
Plasmodium falciparum centrin-4 0.0027 0.0018 0.0091
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0007 0.0021
Mycobacterium tuberculosis Conserved protein 0.0039 0.0035 0.0168
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.8064
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.002 0.0203
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0024 0.0087
Schistosoma mansoni hemoglobinase (C13 family) 0.0605 0.0833 0.0833
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0018 0.0005 0.0005
Onchocerca volvulus Cell death protein 3 homolog 0.0177 0.0229 0.0483
Echinococcus granulosus neuronal calcium sensor 0.0316 0.0426 0.0426
Brugia malayi EF hand family protein 0.0321 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Trypanosoma brucei calpain-like protein, putative 0.201 0.2815 0.8064
Giardia lamblia Cysteine protease 0.0423 0.0577 0.1652
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0029 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.0811 0.1124 0.561
Brugia malayi Cathepsin L-like precursor 0.1381 0.1927 0.1927
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0025 0.007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0011 0.0011
Brugia malayi Cathepsin L-like cysteine proteinase 0.0993 0.138 0.138
Echinococcus granulosus Proteasome subunit alpha beta 0.0018 0.0005 0.0005
Echinococcus granulosus geminin 0.0166 0.0214 0.0214
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.01 0.0121 0.0121
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Plasmodium vivax GPI-anchor transamidase, putative 0.014 0.0178 0.0631
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0011 0.0011
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0018 0.0005 0.0005
Schistosoma mansoni intermediate filament proteins 0.0026 0.0017 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.002 0.0093
Trichomonas vaginalis calmodulin, putative 0.0316 0.0426 0.1219
Plasmodium vivax proteasome subunit beta type-3, putative 0.0018 0.0005 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0168 0.174
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0005 0.0014
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0007 0.0007
Chlamydia trachomatis glycogen phosphorylase 0.0111 0.0136 1
Echinococcus multilocularis calpain family protein 1, d 0.3956 0.5561 0.5561
Entamoeba histolytica proteasome subunit beta type 1, putative 0.007 0.0079 0.0372
Giardia lamblia Cathepsin L precursor 0.0423 0.0577 0.1652
Toxoplasma gondii heat shock protein hslv, putative 0.0018 0.0005 0.0014
Plasmodium vivax vivapain-3 0.0811 0.1124 0.3994
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0104 0.0127 0.0127
Echinococcus granulosus calpain 0.201 0.2815 0.2815
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0018 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0423 0.0577 0.2866
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.7103 1 1
Onchocerca volvulus 0.0751 0.1039 0.2191
Entamoeba histolytica glycogen phosphorylase, putative 0.0111 0.0136 0.0657
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.8064
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0035 0.0035
Giardia lamblia 20S proteasome alpha subunit 4 0.0018 0.0005 0.0014
Entamoeba histolytica GPI-anchor transamidase, putative 0.014 0.0178 0.0866
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Brugia malayi Inositol-1 0.0036 0.0031 0.0031
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0018 0.0005 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0035 0.0035
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Plasmodium falciparum serine repeat antigen 5 0.0423 0.0577 0.2992
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0012 0.0062
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0126 0.0126
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0168 0.048
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0177 0.023 0.023
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0124 0.0124
Plasmodium falciparum flap endonuclease 1 0.0025 0.0015 0.0079
Brugia malayi Probable myosin regulatory light chain 0.0031 0.0024 0.0024
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1711 0.2393 0.2393
Schistosoma mansoni cathepsin S (C01 family) 0.0423 0.0577 0.0577
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.002 0.002
Trypanosoma brucei Component of motile flagella 41 0.0316 0.0426 0.1219
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.004 0.0115
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0605 0.0833 0.2386
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.058 0.0798 0.2285
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Echinococcus multilocularis laminin 0.0015 0.0001 0.0001
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0007 0.0024
Echinococcus multilocularis programmed cell death protein 0.0343 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0035 0.0168
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.0124 0.0124
Loa Loa (eye worm) EF hand family protein 0.0316 0.0426 0.0426
Echinococcus granulosus enteropeptidase 0.01 0.0121 0.0121
Trichomonas vaginalis hypothetical protein 0.058 0.0798 0.2285
Loa Loa (eye worm) hypothetical protein 0.058 0.0798 0.0798
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.002 0.0203
Brugia malayi Cathepsin L-like precursor 0.1381 0.1927 0.1927
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0005 0.0014
Leishmania major centrin, putative 0.0316 0.0426 0.1219
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0039 0.0039
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.0012 0.0012
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0035 0.0035
Brugia malayi proteasome subunit beta type 3 0.0018 0.0005 0.0005
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0047 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.2815
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0021 0.001 0.001
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0031 0.0088
Trypanosoma brucei protein I/6 0.0316 0.0426 0.1219
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0124 0.0124
Loa Loa (eye worm) proteasome subunit beta type 1 0.007 0.0079 0.0079
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.002 0.0203
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0005 0.0005
Plasmodium falciparum mitogen-activated protein kinase 2 0.0166 0.0214 0.1111
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0124 0.0124
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0021 0.006
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.0113 0.0325
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0018 0.0005 0.0005
Brugia malayi aspartic protease BmAsp-1, identical 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.058 0.0798 0.0798
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0116 0.0116
Giardia lamblia Transglutaminase/protease, putative 0.0174 0.0226 0.0647
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0011 0.0011
Trypanosoma brucei centrin, putative 0.0316 0.0426 0.1219
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1711 0.2393 0.6856
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0226 0.1073
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Brugia malayi fibroinase precursor 0.0423 0.0577 0.0577
Echinococcus granulosus peroxidasin 0.0104 0.0126 0.0126
Brugia malayi proteasome subunit alpha type 1 0.0018 0.0005 0.0005
Echinococcus granulosus cathepsin L 0.0423 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0166 0.0214 0.0761
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.002 0.0203
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0116 0.0116
Plasmodium falciparum metacaspase-like protein 0.0043 0.004 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.004 0.0115
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.002 0.0203
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0113 0.0544
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0018 0.0005 0.0014
Entamoeba histolytica calcium binding family protein 0.0316 0.0426 0.2109
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0018 0.0005 0.0005
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0019 0.0006 0.0006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Entamoeba histolytica cysteine protease, putative 0.1381 0.1927 0.9634
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Plasmodium vivax proteasome subunit beta type-1, putative 0.007 0.0079 0.028
Giardia lamblia Cathepsin L precursor 0.0423 0.0577 0.1652
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0007 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0039 0.0039
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0015 0.0015
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0126 0.0126
Leishmania major cathepsin L-like protease 0.1483 0.2072 0.5936
Loa Loa (eye worm) hypothetical protein 0.0045 0.0043 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.002 0.0203
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.004 0.004
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0039 0.0039
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0423 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0993 0.138 0.138
Plasmodium falciparum peptidase, putative 0.0205 0.0269 0.1394
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Entamoeba histolytica hypothetical protein, conserved 0.0205 0.0269 0.1323
Echinococcus multilocularis beta adrenergic receptor kinase 0.0044 0.0042 0.0042
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0316 0.0426 0.1219
Echinococcus granulosus proteasome subunit alpha type 2 0.0018 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.058 0.0798 0.0798
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0024 0.0024
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0166 0.0214 0.0613
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0018 0.0005 0.0017
Brugia malayi calpain 7 0.201 0.2815 0.2815
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0005 0.0014
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Echinococcus multilocularis Mastin 0.01 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0993 0.138 0.138
Schistosoma mansoni hypothetical protein 0.0035 0.0029 0.0029
Leishmania major glucose transporter, lmgt3 0.0032 0.0025 0.007
Plasmodium vivax vivapain-2 0.1381 0.1927 0.6846
Trypanosoma brucei caltractin, putative 0.0343 0.0464 0.1328
Giardia lamblia Thymus-specific serine protease precursor 0.0021 0.001 0.0027
Schistosoma mansoni glycogen phosphorylase 0.0111 0.0136 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0113 0.0325
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0094 0.0112 0.0112
Brugia malayi beta-lactamase 0.0039 0.0035 0.0035
Toxoplasma gondii calcium binding protein precursor, putative 0.0027 0.0018 0.005
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0018 0.0005 0.1539
Plasmodium vivax CDK-related protein kinase 6, putative 0.0436 0.0595 0.2113
Echinococcus granulosus cpg binding protein 0.0061 0.0066 0.0066
Trypanosoma cruzi conserved protein 0.058 0.0798 0.0798
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.058 0.0798 0.0798
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0423 0.0577 0.0577
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.002 0.0203
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0115 0.0115
Echinococcus granulosus neurocalcin 0.0316 0.0426 0.0426
Echinococcus multilocularis endothelin converting enzyme 1 0.0094 0.0112 0.0112
Echinococcus granulosus cathepsin L 0.0811 0.1124 0.1124
Trypanosoma brucei centrin-3 0.0343 0.0464 0.1328
Plasmodium vivax proteasome subunit beta type-2, putative 0.0044 0.0041 0.0146
Onchocerca volvulus Dual oxidase homolog 0.0104 0.0126 0.0267
Entamoeba histolytica glycogen phosphorylase, putative 0.0111 0.0136 0.0657
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.002 0.0093
Toxoplasma gondii microneme protein, putative 0.0029 0.0021 0.006
Brugia malayi cathepsin L-like precursor 0.0993 0.138 0.138
Brugia malayi Cytochrome P450 family protein 0.007 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0316 0.0426 0.1219
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.7103 1 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0011 0.0011
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0035 0.0366
Echinococcus granulosus glycoprotein Antigen 5 0.01 0.0121 0.0121
Toxoplasma gondii proteasome subunit alpha1, putative 0.0018 0.0005 0.0014
Trichomonas vaginalis centrin, putative 0.0316 0.0426 0.1219
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0423 0.0577 0.0577
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0039 0.0039
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0008 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.002 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Echinococcus multilocularis cysteine protease 0.1381 0.1927 0.1927
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0423 0.0577 0.2049
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.002 0.0093
Brugia malayi beta-lactamase family protein 0.0039 0.0035 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0811 0.1124 0.561
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0007 0.0013
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0041 0.0041
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.01 0.0121 0.0121
Brugia malayi RasGEF domain containing protein 0.0027 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0177 0.023 0.023
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0015 0.0044
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.0113 0.0113
Mycobacterium tuberculosis Probable peptidase 0.0698 0.0964 0.458
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0011 0.0011
Brugia malayi calpain 5 0.058 0.0798 0.0798
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0536 0.0736 0.0736
Loa Loa (eye worm) hypothetical protein 0.0043 0.004 0.004
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0018 0.0005 0.0005
Echinococcus granulosus transmembrane protease serine 3 0.01 0.0121 0.0121
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0018 0.0005 0.0025
Trypanosoma brucei calpain, putative 0.058 0.0798 0.2285
Plasmodium falciparum serine repeat antigen 2 0.0423 0.0577 0.2992
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0605 0.0833 0.2386
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0062 0.0062
Brugia malayi hypothetical protein 0.0134 0.0169 0.0169
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Echinococcus granulosus Calcium binding protein 0.0027 0.0018 0.0018
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0019 0.0006 0.0006
Entamoeba histolytica grainin, putative 0.0321 0.0432 0.2141
Leishmania major hypothetical protein, conserved 0.0039 0.0035 0.0101
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0113 0.0113
Trypanosoma brucei Calpain-like protein 2 0.058 0.0798 0.2285
Brugia malayi cathepsin F-like cysteine proteinase 0.0423 0.0577 0.0577
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0047 0.0047
Echinococcus multilocularis Calcium binding protein 0.0027 0.0018 0.0018
Leishmania major proteasome alpha 1 subunit, putative 0.0018 0.0005 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0423 0.0577 0.1652
Onchocerca volvulus Peroxidase homolog 0.0104 0.0126 0.0267
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0698 0.0964 0.2761
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Echinococcus granulosus cathepsin l cysteine peptidase 0.1381 0.1927 0.1927
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Toxoplasma gondii calmodulin CAM1 0.0321 0.0432 0.1237
Schistosoma mansoni neuronal calcium sensor 0.0316 0.0426 0.0426
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Brugia malayi carbohydrate phosphorylase 0.0111 0.0136 0.0136
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0091 0.0107 0.051
Echinococcus granulosus calcium uptake protein 1 0.0321 0.0432 0.0432
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0013 0.0013
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0423 0.0577 0.0577
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0126 0.0126
Brugia malayi EF hand family protein 0.0316 0.0426 0.0426
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0024 0.007
Plasmodium vivax serine-repeat antigen (SERA) 0.0423 0.0577 0.2049
Plasmodium falciparum cysteine proteinase falcipain 3 0.1381 0.1927 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.002 0.0093
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0039 0.0039
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0018 0.0005 0.0025
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0205 0.0269 0.077
Giardia lamblia Cathepsin B precursor 0.0423 0.0577 0.1652
Schistosoma mansoni protein kinase 0.0032 0.0024 0.0024
Onchocerca volvulus Legumain homolog 0.0605 0.0833 0.1756
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.003 0.003
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0024 0.0024
Plasmodium falciparum proteasome subunit beta type-4 0.0018 0.0005 0.0025
Onchocerca volvulus Notchless protein homolog 0.0018 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0039 0.0111
Plasmodium vivax unspecified product 0.0423 0.0577 0.2049
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.003 0.003
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.003 0.0108
Trichomonas vaginalis glycogen phosphorylase, putative 0.0111 0.0136 0.0389
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0316 0.0426 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0039 0.0111
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Onchocerca volvulus Prolyl endopeptidase homolog 0.1711 0.2393 0.5047
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0205 0.0269 0.077
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.014 0.0178 0.0509
Giardia lamblia Hypothetical protein 0.0423 0.0577 0.1652
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0007 0.0034
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.002 0.0154
Brugia malayi Pre-SET motif family protein 0.066 0.091 0.091
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0011 0.0011
Echinococcus granulosus proteasome subunit beta t family 0.0018 0.0005 0.0005
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0205 0.0269 0.1323
Giardia lamblia Calmodulin 0.0027 0.0018 0.005
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0025 0.007
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0124 0.0124
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0168 0.174
Leishmania major calmodulin, putative 0.0316 0.0426 0.1219
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0605 0.0833 0.2386
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.002 0.0093
Leishmania major cathepsin L-like protease 0.1483 0.2072 0.5936
Leishmania major proteasome beta 3 subunit, putative 0.0018 0.0005 0.0014
Echinococcus granulosus calpain A 0.201 0.2815 0.2815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Onchocerca volvulus 0.0022 0.0011 0.0023
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0021 0.0021
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0025 0.0216
Loa Loa (eye worm) hypothetical protein 0.007 0.0078 0.0078
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0011 0.0011
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0297 0.0399 0.1143
Trichomonas vaginalis centrin, putative 0.0027 0.0018 0.005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0116 0.0116
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0824 0.1142 0.1142
Echinococcus multilocularis centrin 2 0.0316 0.0426 0.0426
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.01 0.0121 0.0121
Trypanosoma cruzi cruzipain precursor, putative 0.1483 0.2072 0.2072
Mycobacterium ulcerans hypothetical protein 0.0174 0.0226 0.2343
Leishmania major cathepsin L-like protease 0.1381 0.1927 0.5521
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Entamoeba histolytica calcium-binding protein, putative 0.0316 0.0426 0.2109
Schistosoma mansoni hypothetical protein 0.0464 0.0635 0.0635
Trypanosoma brucei centrin, putative 0.0316 0.0426 0.1219
Echinococcus granulosus tumor protein p63 0.0369 0.05 0.05
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0041 0.0118
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.014 0.0178 0.0509
Plasmodium falciparum plasmepsin I 0.0019 0.0006 0.0033
Trypanosoma cruzi I/6 autoantigen, putative 0.0316 0.0426 0.0426
Echinococcus granulosus caspase 2 0.0177 0.0229 0.0229
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0013 0.0043
Toxoplasma gondii proteasome subunit alpha type, putative 0.0018 0.0005 0.0014
Loa Loa (eye worm) calpain family protein 1 0.5386 0.7578 0.7578
Echinococcus granulosus GPI anchor transamidase 0.014 0.0178 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.004 0.0115
Brugia malayi prolyl oligopeptidase family protein 0.1711 0.2393 0.2393
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0035 0.0035
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0011 0.0011
Leishmania major proteasome beta 2 subunit, putative 0.0018 0.0005 0.0014
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.003 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0042 0.0042
Echinococcus multilocularis calmodulin 0.0316 0.0426 0.0426
Trypanosoma brucei cysteine peptidase, putative 0.058 0.0798 0.2285
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Echinococcus granulosus flap endonuclease 1 0.0025 0.0015 0.0015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0159 0.0159
Echinococcus multilocularis glycogen phosphorylase 0.0111 0.0136 0.0136
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Schistosoma mansoni hypothetical protein 0.0174 0.0226 0.0226
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0316 0.0426 0.1219
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.002 0.0203
Leishmania major hypothetical protein, conserved 0.0316 0.0426 0.1219
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0018 0.0005 0.0014
Trypanosoma cruzi calmodulin, putative 0.0316 0.0426 0.0426
Trypanosoma brucei calmodulin, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) hypothetical protein 0.01 0.0121 0.0121
Schistosoma mansoni centrin-related 0.0316 0.0426 0.0426
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0698 0.0964 0.2761
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0044 0.0041 0.0118
Entamoeba histolytica cysteine proteinase, putative 0.0811 0.1124 0.561
Echinococcus multilocularis cpg binding protein 0.0061 0.0066 0.0066
Echinococcus granulosus programmed cell death protein 0.0343 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.4806 0.676 0.676
Echinococcus granulosus EF HAND 1 calcium binding site 0.0316 0.0426 0.0426
Schistosoma mansoni lamin 0.0026 0.0017 0.0017
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.0012 0.0012
Echinococcus multilocularis caspase 8 0.0043 0.004 0.004
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0024 0.0127
Giardia lamblia 20S proteasome alpha subunit 3 0.0018 0.0005 0.0014
Schistosoma mansoni Mername-AA248 (C02 family) 0.201 0.2815 0.2815
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.01 0.0121 0.0121
Giardia lamblia GPI-anchor transamidase, putative 0.014 0.0178 0.0509
Schistosoma mansoni kinase 0.0049 0.0049 0.0049
Schistosoma mansoni glycogen phosphorylase 0.0048 0.0047 0.0047
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0177 0.023 0.023
Trypanosoma cruzi cysteine peptidase, putative 0.1483 0.2072 0.2072
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0039 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0011 0.0011
Echinococcus granulosus cathepsin b 0.7103 1 1
Brugia malayi Cathepsin L-like precursor 0.0388 0.0527 0.0527
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.201 0.2815 0.8064
Leishmania major proteasome alpha 7 subunit, putative 0.0018 0.0005 0.0014
Brugia malayi steroid hormone receptor 0.0022 0.0011 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Onchocerca volvulus 0.0104 0.0126 0.0267
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0019 0.0006 0.0018
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0423 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0423 0.0577 0.0577
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Plasmodium falciparum serine repeat antigen 7 0.0423 0.0577 0.2992
Trichomonas vaginalis glycogen phosphorylase, putative 0.0111 0.0136 0.0389
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0023 0.0023
Entamoeba histolytica cysteine protease, putative 0.0423 0.0577 0.2866
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.5702 0.8024 0.8024
Brugia malayi Cytochrome P450 family protein 0.0047 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Echinococcus multilocularis calumenin 0.0321 0.0432 0.0432
Trichomonas vaginalis calmodulin, putative 0.0321 0.0432 0.1237
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0018 0.0005 0.0005
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0018 0.0005 0.0014
Trypanosoma cruzi prolyl endopeptidase 0.1711 0.2393 0.2393
Giardia lamblia Proteasome subunit beta type 3 0.0018 0.0005 0.0014
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.01 0.0121 0.0121
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0024 0.007
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.0113 0.0239
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.058 0.0798 0.0798
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0269 0.0269
Giardia lamblia Kinase, PLK 0.0095 0.0113 0.0325
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0226 0.1073
Schistosoma mansoni hypothetical protein 0.0316 0.0426 0.0426
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0031 0.0031
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0316 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.007 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0177 0.023 0.023
Loa Loa (eye worm) histone methyltransferase 0.0021 0.001 0.001
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0012 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0811 0.1124 0.1124
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0012 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2489 0.3491 0.3491
Trypanosoma brucei proteasome beta 6 subunit 0.007 0.0079 0.0226
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0023 0.0023
Loa Loa (eye worm) blistered cuticle protein 3 0.0104 0.0126 0.0126
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0078 0.0078
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Giardia lamblia Cathepsin B precursor 0.0423 0.0577 0.1652
Onchocerca volvulus 0.1381 0.1927 0.4064
Giardia lamblia 20S proteasome alpha subunit 1 0.0018 0.0005 0.0014
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0423 0.0577 0.0577
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0044 0.0044
Trichomonas vaginalis calcium binding protein, putative 0.0343 0.0464 0.1328
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0423 0.0577 0.1652
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0018 0.0005 0.0025
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0021 0.006
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0114 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Schistosoma mansoni lamin 0.0026 0.0017 0.0017
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0423 0.0577 0.2866
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.014 0.0178 0.0178
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.058 0.0798 0.2285
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0018 0.0005 0.0005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0115 0.0115
Plasmodium vivax hypothetical protein, conserved 0.0321 0.0432 0.1534
Loa Loa (eye worm) hypothetical protein 0.0134 0.0169 0.0169
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0177 0.023 0.023
Onchocerca volvulus 0.0029 0.0021 0.0044
Leishmania major cathepsin L-like protease 0.1381 0.1927 0.5521
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0018 0.0005 0.0025
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0005 0.0014
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0039 0.0039
Brugia malayi CXXC zinc finger family protein 0.0058 0.0062 0.0062
Leishmania major cytochrome p450-like protein 0.0028 0.002 0.0056
Trypanosoma cruzi oligopeptidase b 0.0698 0.0964 0.0964
Loa Loa (eye worm) hypothetical protein 0.0094 0.0112 0.0112
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0031 0.0088
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0018 0.0005 0.0005
Trypanosoma brucei calpain-like protein, putative 0.201 0.2815 0.8064
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0012 0.0012
Loa Loa (eye worm) calpain 5 0.143 0.1997 0.1997
Echinococcus multilocularis glycogen phosphorylase 0.0111 0.0136 0.0136
Toxoplasma gondii EFHC1, putative 0.0316 0.0426 0.1219
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0811 0.1124 0.3221
Leishmania major protein kinase, putative 0.0032 0.0024 0.007
Schistosoma mansoni caspase-7 (C14 family) 0.0114 0.014 0.014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Trypanosoma cruzi cysteine peptidase, putative 0.1483 0.2072 0.2072
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Mycobacterium leprae Conserved hypothetical protein 0.0174 0.0226 0.2305
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0024 0.0024
Echinococcus granulosus calcyphosin protein 0.0027 0.0018 0.0018
Trichomonas vaginalis peptide N-glycanase, putative 0.0174 0.0226 0.0647
Entamoeba histolytica hypothetical protein 0.0035 0.0029 0.0124
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0011 0.0011
Plasmodium falciparum plasmepsin II 0.0019 0.0006 0.0033
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0297 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0168 0.174
Schistosoma mansoni cpg binding protein 0.0061 0.0066 0.0066
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.002 0.0203
Leishmania major kinesin, putative 0.143 0.1997 0.5721
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Brugia malayi Myosin regulatory light chain 1 0.0027 0.0018 0.0018
Giardia lamblia Cathepsin L precursor 0.0423 0.0577 0.1652
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0018 0.0005 0.0005
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0047 0.0047
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0011 0.0011
Trichomonas vaginalis calmodulin, putative 0.0316 0.0426 0.1219
Leishmania major cysteine peptidase A (CPA) 0.1381 0.1927 0.5521
Onchocerca volvulus Cathepsin L homolog 0.1381 0.1927 0.4064
Mycobacterium leprae putative cytochrome p450 0.0028 0.002 0.0154
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0035 0.0101
Schistosoma mansoni mitochondrial solute carrier 0.0316 0.0426 0.0426
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0024 0.0024
Mycobacterium ulcerans zinc metalloprotease 0.0094 0.0112 0.1166
Entamoeba histolytica prolyl oligopeptidase family protein 0.0205 0.0269 0.1323
Plasmodium vivax calpain, putative 0.201 0.2815 1
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Toxoplasma gondii hypothetical protein 0.058 0.0798 0.2285
Loa Loa (eye worm) hypothetical protein 0.0094 0.0112 0.0112
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0007 0.0021
Entamoeba histolytica calpain large subunit domain III containing protein 0.143 0.1997 0.9984
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.002 0.0203
Giardia lamblia Cathepsin L precursor 0.0423 0.0577 0.1652
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0041 0.0041
Trypanosoma brucei oligopeptidase b 0.0698 0.0964 0.2761
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0025 0.0025
Trypanosoma cruzi I/6 autoantigen, putative 0.0316 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.01 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.008
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Schistosoma mansoni ap endonuclease 0.002 0.0007 0.0007
Trypanosoma brucei calpain-like protein, putative 0.201 0.2815 0.8064
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0116 0.0116
Brugia malayi calpain 5 0.143 0.1997 0.1997
Trypanosoma cruzi cysteine peptidase, putative 0.0811 0.1124 0.1124
Brugia malayi beta-lactamase family protein 0.0039 0.0035 0.0035
Echinococcus multilocularis lamin 0.0026 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.058 0.0798 0.2285
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0012 0.0012
Schistosoma mansoni coup transcription factor 0.0022 0.0011 0.0011
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0023 0.0066
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0091 0.0107 0.0308
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0017
Giardia lamblia Glycogen phosphorylase 0.0111 0.0136 0.0389
Entamoeba histolytica protein kinase, putative 0.1432 0.2 1
Entamoeba histolytica cysteine protease, putative 0.0423 0.0577 0.2866
Brugia malayi Trypsin family protein 0.01 0.0121 0.0121
Echinococcus granulosus subfamily T1A non peptidase ue 0.0018 0.0005 0.0005
Echinococcus granulosus centrin 2 0.0316 0.0426 0.0426
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0021 0.006
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0011 0.0011
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0423 0.0577 0.0577
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0047 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0423 0.0577 0.0577
Trichomonas vaginalis calmodulin, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1381 0.1927 0.1927
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0015 0.0015
Leishmania major metacaspase, putative 0.0043 0.004 0.0115
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.01 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.002 0.0203
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0023
Brugia malayi cathepsin L-like cysteine proteinase 0.0423 0.0577 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0423 0.0577 0.1652
Entamoeba histolytica cysteine proteinase, putative 0.0811 0.1124 0.561
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0018 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0168 0.048
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0007 0.0007
Plasmodium falciparum proteasome subunit beta type-5 0.0091 0.0107 0.0557
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0536 0.0736 0.0736
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0015 0.0001 0.0001
Echinococcus multilocularis cathepsin L 0.0423 0.0577 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0423 0.0577 0.1652
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0811 0.1124 0.1124
Mycobacterium ulcerans putative transglutaminase-like protein 0.0174 0.0226 0.2343
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0423 0.0577 0.2992
Echinococcus multilocularis calpain 5 0.201 0.2815 0.2815
Echinococcus granulosus caspase 8 0.0043 0.004 0.004
Trypanosoma cruzi centrin-3 0.0343 0.0464 0.0464
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0024 0.0087
Echinococcus granulosus programmed cell death protein 6 0.0032 0.0024 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0047 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Trypanosoma brucei Calpain-like protein CALP1.3 0.058 0.0798 0.2285
Entamoeba histolytica hypothetical protein 0.0042 0.0039 0.017
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0316 0.0426 0.0426
Onchocerca volvulus 0.0021 0.001 0.002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0007 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.002 0.0093
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0039 0.0039
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0024 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0113 0.0325
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.007 0.0079 0.0226
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0423 0.0577 0.1652
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0043 0.004 0.004
Plasmodium vivax proteasome subunit beta type-4, putative 0.0018 0.0005 0.0017
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0021 0.0021
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.1711 0.2393 0.2393
Schistosoma mansoni hypothetical protein 0.0103 0.0124 0.0124
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0423 0.0577 0.1652
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0039 0.0039
Echinococcus granulosus proteasome subunit alpha type 6 0.0018 0.0005 0.0005
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0205 0.0269 0.0269
Trichomonas vaginalis calmodulin, putative 0.0027 0.0018 0.005
Onchocerca volvulus 0.01 0.0121 0.0256
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0015 0.0052
Trypanosoma brucei glucose transporter 1E 0.0032 0.0025 0.007
Leishmania major proteasome alpha 2 subunit, putative 0.0018 0.0005 0.0014
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0698 0.0964 0.458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Brugia malayi Papain family cysteine protease containing protein 0.0423 0.0577 0.0577
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0091 0.0107 0.0107
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0005 0.0005
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0013 0.0013
Brugia malayi ecdysteroid receptor 0.0022 0.0011 0.0011
Brugia malayi intermediate filament protein 0.0026 0.0017 0.0017
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.058 0.0798 0.0798
Schistosoma mansoni hypothetical protein 0.0316 0.0426 0.0426
Plasmodium falciparum protein kinase 6 0.0436 0.0595 0.3086
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0536 0.0736 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0011 0.0011
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0091 0.0107 0.1071
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0042 0.0042
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0007 0.2364
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0039 0.0039
Brugia malayi calpain family protein 1 0.5386 0.7578 0.7578
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0013 0.0038
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0423 0.0577 0.0577
Toxoplasma gondii peptidase, T1 family protein 0.0018 0.0005 0.0014
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0126 0.0126
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0018 0.0005 0.0005
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0021 0.001 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0011 0.0011
Trichomonas vaginalis set domain proteins, putative 0.0751 0.1039 0.2976
Onchocerca volvulus 0.0104 0.0126 0.0267
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0044 0.0042 0.0042
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0605 0.0833 0.2386
Toxoplasma gondii ABC1 family protein 0.0039 0.0035 0.0101
Onchocerca volvulus 0.0019 0.0006 0.0013
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.058 0.0798 0.2285
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0011 0.0011
Trypanosoma cruzi cruzipain precursor, putative 0.0388 0.0527 0.0527
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.5702 0.8024 0.8024
Brugia malayi Calmodulin-like protein 0.0316 0.0426 0.0426
Trypanosoma brucei metacaspase MCA2 0.0043 0.004 0.0115
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0025 0.007
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Echinococcus granulosus lamin 0.0026 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0423 0.0577 0.1652
Onchocerca volvulus 0.0047 0.0045 0.0096
Echinococcus multilocularis musashi 0.0026 0.0017 0.0017
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0047 0.0213
Entamoeba histolytica hypothetical protein 0.0035 0.0029 0.0124
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.007 0.0079 0.0079
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0013 0.0047
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.014 0.0178 0.0178
Entamoeba histolytica cysteine proteinase, putative 0.0993 0.138 0.6891
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0025 0.007
Loa Loa (eye worm) hypothetical protein 0.0993 0.138 0.138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0423 0.0577 0.1652
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0423 0.0577 0.1652
Echinococcus multilocularis calpain 7 (C02 family) 0.201 0.2815 0.2815
Loa Loa (eye worm) AStacin protease 0.0029 0.0021 0.0021
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0021 0.006
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.002 0.0203
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0013 0.0028
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.058 0.0798 0.0798
Loa Loa (eye worm) CYP4Cod1 0.0047 0.0047 0.0047
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.002 0.0203
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1381 0.1927 0.5521
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0005 0.0014
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0388 0.0527 0.0527
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0044 0.0041 0.0041
Onchocerca volvulus 0.0054 0.0056 0.0118
Toxoplasma gondii cathepsin B 0.2489 0.3491 1
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0024 0.0024
Leishmania major proteasome beta 2 subunit, putative 0.0044 0.0041 0.0118
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.014 0.0178 0.0509
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0023 0.0023
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0021 0.006
Brugia malayi Papain family cysteine protease containing protein 0.1381 0.1927 0.1927
Loa Loa (eye worm) prolyl oligopeptidase 0.0205 0.0269 0.0269
Plasmodium vivax SET domain protein, putative 0.0096 0.0115 0.0407
Echinococcus multilocularis proteasome subunit alpha type 6 0.0018 0.0005 0.0005
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.0024 0.0024
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0007 0.0026
Onchocerca volvulus 0.0177 0.023 0.0485
Echinococcus multilocularis caspase 3 0.0071 0.0079 0.0079
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0047 0.0135
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Toxoplasma gondii calmodulin CAM2 0.0027 0.0018 0.005
Plasmodium vivax proteasome subunit beta type-6, putative 0.0018 0.0005 0.0017
Loa Loa (eye worm) hypothetical protein 0.0177 0.0229 0.0229
Schistosoma mansoni neprilysin 0.0025 0.0014 0.0014
Onchocerca volvulus 0.0039 0.0035 0.0074
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Schistosoma mansoni hypothetical protein 0.0134 0.0169 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0811 0.1124 0.3221
Echinococcus granulosus Dipeptidyl peptidase 9 0.0297 0.0399 0.0399
Onchocerca volvulus 0.3376 0.4742 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.0013
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.014 0.0401
Loa Loa (eye worm) inositol-1 0.0036 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0166 0.0214 0.0214
Giardia lamblia Cysteine protease 0.0423 0.0577 0.1652
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0055 0.0055
Treponema pallidum ATP-dependent RNA helicase 0.0024 0.0013 1
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0394 0.0535 0.0535
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0018 0.0005 0.0014
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0005 0.0005
Schistosoma mansoni inositol monophosphatase 0.0036 0.0031 0.0031
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0015 0.0015
Schistosoma mansoni ap endonuclease 0.002 0.0007 0.0007
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0039 0.0039
Onchocerca volvulus 0.0029 0.0021 0.0044
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0126 0.0126
Loa Loa (eye worm) beta-lactamase 0.0039 0.0035 0.0035
Trypanosoma cruzi cysteine proteinase, putative 0.0811 0.1124 0.1124
Trypanosoma cruzi caltractin, putative 0.0316 0.0426 0.0426
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.0006 0.0006
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0013 0.0038
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.003 0.0087
Toxoplasma gondii aspartyl protease ASP1 0.0019 0.0006 0.0018
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0025 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0423 0.0577 0.1652
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0348 0.047 0.1671
Loa Loa (eye worm) aspartyl protease 6 0.0019 0.0006 0.0006
Leishmania major i/6 autoantigen-like protein 0.0316 0.0426 0.1219
Plasmodium falciparum serine repeat antigen 3 0.0423 0.0577 0.2992
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0115 0.0115
Brugia malayi Pre-SET motif family protein 0.0096 0.0115 0.0115
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0005 0.0005
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0018 0.0005 0.0014
Toxoplasma gondii proteasome subunit 0.0018 0.0005 0.0014
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0039 0.0039
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0005 0.0005
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0094 0.0112 0.0112
Giardia lamblia Cathepsin B precursor 0.0423 0.0577 0.1652
Trypanosoma cruzi major cysteine proteinase, putative 0.0423 0.0577 0.0577
Brugia malayi Proteasome subunit alpha type 7-1 0.0018 0.0005 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0423 0.0577 0.0577
Brugia malayi hypothetical protein 0.01 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0177 0.023 0.023
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.002 0.0093
Loa Loa (eye worm) peptidase C13 family protein 0.0605 0.0833 0.0833
Trypanosoma brucei kinesin, putative 0.143 0.1997 0.5721
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Brugia malayi Cathepsin L-like precursor 0.1381 0.1927 0.1927
Giardia lamblia Hypothetical protein 0.0423 0.0577 0.1652
Plasmodium falciparum GPI-anchor transamidase, putative 0.014 0.0178 0.0921
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.004 0.0115
Toxoplasma gondii cathepsin CPC1 0.0423 0.0577 0.1652
Plasmodium falciparum metacaspase 1 0.0043 0.004 0.0209
Brugia malayi Peptidase C13 family protein 0.0605 0.0833 0.0833
Toxoplasma gondii hypothetical protein 0.0205 0.0269 0.077
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0024 0.0024
Echinococcus granulosus endothelin converting enzyme 1 0.0094 0.0112 0.0112
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0056 0.0056
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0091 0.0107 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0025 0.007
Brugia malayi cathepsin L precursor 0.0423 0.0577 0.0577
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0018 0.0005 0.0005
Schistosoma mansoni calpain C (C02 family) 0.201 0.2815 0.2815
Schistosoma mansoni cathepsin C 0.0423 0.0577 0.0577
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0011 0.0011
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0011 0.0023
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.0012 0.0012
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.001 0.0027
Toxoplasma gondii centrin family protein 0.0027 0.0018 0.005
Giardia lamblia Hypothetical protein 0.0321 0.0432 0.1237
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0021 0.006
Onchocerca volvulus Chorion peroxidase homolog 0.0104 0.0126 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0423 0.0577 0.1652
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.002 0.002
Onchocerca volvulus 0.01 0.0121 0.0256
Onchocerca volvulus 0.0029 0.0021 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.004 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0011 0.0011
Schistosoma mansoni protein kinase 0.0032 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Schistosoma mansoni survival motor neuron protein 0.0053 0.0055 0.0055
Mycobacterium leprae Probable lipase LipE 0.0039 0.0035 0.0318
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0013 0.0013
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0297 0.0399 0.1143
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0018 0.0005 0.0005
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0115 0.0328
Trichomonas vaginalis myosin light chain 1, putative 0.0316 0.0426 0.1219
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0027 0.0018 0.005
Plasmodium vivax hypothetical protein, conserved 0.0043 0.004 0.0143
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0012 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0993 0.138 0.3952
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.008
Loa Loa (eye worm) calpain 0.201 0.2815 0.2815
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.066 0.091 0.091
Echinococcus granulosus cysteine protease 0.0811 0.1124 0.1124
Trypanosoma cruzi Aph-1 protein, putative 0.0109 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.7103 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Trypanosoma brucei proteasome alpha 7 subunit 0.0018 0.0005 0.0014
Giardia lamblia Alanyl dipeptidyl peptidase 0.0205 0.0269 0.077
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0041 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0035 0.0035
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0018 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0039 0.0111
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0018 0.0005 0.0005
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0316 0.0426 0.0426
Giardia lamblia Cathepsin B precursor 0.2489 0.3491 1
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.0006 0.0022
Loa Loa (eye worm) proteasome subunit beta type 2 0.0044 0.0041 0.0041
Plasmodium vivax unspecified product 0.0811 0.1124 0.3994
Trypanosoma brucei prolyl oligopeptidase, putative 0.0698 0.0964 0.2761
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0811 0.1124 0.3221
Loa Loa (eye worm) myosin Light Chain family member 0.0031 0.0024 0.0024
Onchocerca volvulus 0.0029 0.0021 0.0044
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0018 0.0005 0.0014
Giardia lamblia 20S proteasome alpha subunit 2 0.0018 0.0005 0.0014
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Echinococcus granulosus Tolloid protein 1 0.0047 0.0046 0.0046
Toxoplasma gondii proteasome subunit beta type 1, putative 0.007 0.0079 0.0226
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Brugia malayi nuclear receptor NHR-88 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.01 0.0121 0.0121
Trypanosoma cruzi centrin, putative 0.0343 0.0464 0.0464
Trypanosoma brucei glucose transporter 2A 0.0032 0.0025 0.007
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.002 0.0093
Plasmodium vivax serine-repeat antigen (SERA) 0.0423 0.0577 0.2049
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0423 0.0577 0.2049
Echinococcus multilocularis programmed cell death protein 0.0343 0.0464 0.0464
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0605 0.0833 0.2386
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0035 0.0035
Leishmania major centrin, putative,caltractin, putative 0.0316 0.0426 0.1219
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0025 0.007
Onchocerca volvulus 0.0045 0.0044 0.0092
Loa Loa (eye worm) hypothetical protein 0.01 0.0121 0.0121
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0605 0.0833 0.0833
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.002 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0011 0.0011
Trichomonas vaginalis centrin, putative 0.0027 0.0018 0.005
Echinococcus granulosus cathepsin b 0.7103 1 1
Trypanosoma brucei calmodulin, putative 0.0321 0.0432 0.1237
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.001 0.001
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0019 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0828 0.1148 0.1148
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0423 0.0577 0.1652
Schistosoma mansoni calpain-2 (C02 family) 0.058 0.0798 0.0798
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.001 0.001
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0698 0.0964 0.0964
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.058 0.0798 0.2285
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0025 0.007
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0039 0.0039
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0011 0.0011
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0018 0.0005 0.0025
Onchocerca volvulus 0.01 0.0121 0.0256
Brugia malayi Kringle domain containing protein 0.0045 0.0044 0.0044
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0005 0.0005
Brugia malayi Cell death protein 3 precursor 0.0177 0.0229 0.0229
Mycobacterium ulcerans hypothetical protein 0.0039 0.0035 0.0366
Echinococcus granulosus beta-adrenergic receptor kinase 0.0044 0.0042 0.0042
Onchocerca volvulus 0.0029 0.0021 0.0044
Brugia malayi peptidase family M13 containing protein 0.0023 0.0012 0.0012
Leishmania major cathepsin L-like protease 0.1483 0.2072 0.5936
Giardia lamblia Programmed cell death protein-like protein 0.0027 0.0018 0.005
Onchocerca volvulus 0.0029 0.0021 0.0044
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0044 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0205 0.0269 0.077
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0025 0.007
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.002 0.0008 0.0016
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0039 0.0111
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0423 0.0577 0.1652
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0024 0.007
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Trichomonas vaginalis calcium binding protein, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) hypothetical protein 0.5386 0.7578 0.7578
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.001 0.001
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0018 0.0005 0.0014
Brugia malayi PXA domain containing protein 0.0042 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.01 0.0121 0.0121
Echinococcus granulosus cathepsin L cysteine proteinase 0.1381 0.1927 0.1927
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1381 0.1927 0.1927
Brugia malayi prolyl oligopeptidase family protein 0.0205 0.0269 0.0269
Trypanosoma brucei Aph-1 protein, putative 0.0109 0.0134 0.0383
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0044 0.0041 0.0182
Echinococcus multilocularis calpain 0.201 0.2815 0.2815
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0316 0.0426 0.1219
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0013 0.0013
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.01 0.0121 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.058 0.0798 0.2285
Trypanosoma cruzi major cysteine proteinase, putative 0.0526 0.0722 0.0722
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0168 0.0168
Giardia lamblia Cathepsin B precursor 0.0423 0.0577 0.1652
Schistosoma mansoni calmodulin 0.0316 0.0426 0.0426
Echinococcus granulosus proteasome prosome macropain 0.0091 0.0107 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0113 0.0325
Brugia malayi GPI-anchor transamidase 0.014 0.0178 0.0178
Schistosoma mansoni cpg binding protein 0.0061 0.0066 0.0066
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0811 0.1124 0.1124
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0698 0.0964 1
Plasmodium falciparum serine repeat antigen 9 0.0423 0.0577 0.2992
Loa Loa (eye worm) PAS-3 protein 0.0018 0.0005 0.0005
Echinococcus multilocularis calcium uptake protein 1 0.0321 0.0432 0.0432
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0605 0.0833 0.2386
Echinococcus multilocularis lamin dm0 0.0026 0.0017 0.0017
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0005 0.0005
Loa Loa (eye worm) sugar transporter 0.0103 0.0124 0.0124
Onchocerca volvulus 0.0053 0.0055 0.0115
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0019 0.0006 0.0006
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0021 0.0021
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0079 0.0226
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0205 0.0269 0.1323
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0423 0.0577 0.2992
Onchocerca volvulus 0.0019 0.0006 0.0013
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0023 0.0066
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0316 0.0426 0.2109
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0018 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Entamoeba histolytica hypothetical protein 0.0035 0.0029 0.0124
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.7103 1 1
Onchocerca volvulus 0.0174 0.0226 0.0476
Loa Loa (eye worm) hypothetical protein 0.0047 0.0045 0.0045
Echinococcus granulosus EF hand domain containing family member A2 0.0321 0.0432 0.0432
Trypanosoma brucei prolyl endopeptidase 0.1711 0.2393 0.6856
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0011 0.0011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0005 0.0005
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0698 0.0964 0.0964
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0039 0.0039
Giardia lamblia Cathepsin B precursor 0.0423 0.0577 0.1652
Brugia malayi Trypsin-like protease protein 5 0.01 0.0121 0.0121
Onchocerca volvulus 0.0029 0.0021 0.0044
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.1927 0.5521
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0029 0.0029
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Giardia lamblia Cysteine protease 0.0423 0.0577 0.1652
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0021 0.006
Toxoplasma gondii aspartyl protease ASP3 0.0019 0.0006 0.0018
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0091 0.0107 0.0107
Schistosoma mansoni flap endonuclease-1 0.0023 0.0012 0.0012
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0018 0.0005 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0011 0.0011
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0018 0.0005 0.0014
Echinococcus granulosus Proteasome subunit alpha type 7 0.0018 0.0005 0.0005
Toxoplasma gondii EF hand domain-containing protein 0.0316 0.0426 0.1219
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0047 0.0047
Onchocerca volvulus Glycogen phosphorylase homolog 0.0111 0.0136 0.0287
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.007 0.0078 0.0078
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0153 0.0153
Trichomonas vaginalis calcineurin B subunit, putative 0.0321 0.0432 0.1237
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0039 0.0039
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0035 0.0168
Plasmodium falciparum hexose transporter 0.0103 0.0124 0.0646
Loa Loa (eye worm) hypothetical protein 0.0316 0.0426 0.0426
Brugia malayi Trypsin family protein 0.01 0.0121 0.0121
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0011 0.0011
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0018 0.0005 0.0005
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.002 0.0093
Toxoplasma gondii centrin 0.0316 0.0426 0.1219
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Mycobacterium ulcerans lipase LipD 0.0039 0.0035 0.0366
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0005 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0056
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0011 0.0011
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0047 0.0047
Brugia malayi proteasome subunit beta type 1 0.007 0.0079 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0011 0.0011
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0014 0.0014
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0394 0.0535 0.0535
Mycobacterium tuberculosis Long conserved protein 0.0174 0.0226 0.1073
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.5386 0.7578 0.7578
Trypanosoma cruzi 20S proteasome subunit 0.0044 0.0041 0.0041
Trypanosoma brucei metacaspase 5, putative 0.0043 0.004 0.0115
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0114 0.014 0.014
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0047 0.0046 0.0046
Onchocerca volvulus Peroxidasin homolog 0.0104 0.0126 0.0267
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0113 0.0325
Loa Loa (eye worm) hypothetical protein 0.0096 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0005 0.0005
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0018 0.0005 0.0017
Entamoeba histolytica calmodulin, putative 0.0027 0.0018 0.0065
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0018 0.0005 0.0017
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.058 0.0798 0.2285
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0012 0.0034
Schistosoma mansoni calpain-7 (C02 family) 0.2013 0.282 0.282
Loa Loa (eye worm) calpain family protein 1 0.3956 0.5561 0.5561
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0039 0.0039
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0027 0.0018 0.0037
Loa Loa (eye worm) myosin regulatory light chain 1 0.0027 0.0018 0.0018
Leishmania major cytochrome p450-like protein 0.0047 0.0047 0.0133
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0013 0.0038
Loa Loa (eye worm) calmodulin-like protein 0.0316 0.0426 0.0426
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0021 0.006
Onchocerca volvulus 0.1381 0.1927 0.4064
Schistosoma mansoni calmodulin 0.0316 0.0426 0.0426
Brugia malayi gamma-secretase subunit aph-1 0.028 0.0375 0.0375
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0005 0.0005
Schistosoma mansoni hemoglobinase (C13 family) 0.0605 0.0833 0.0833
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.002 0.0056
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0013 0.0038
Echinococcus granulosus cathepsin L cysteine protease 0.0811 0.1124 0.1124
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0021 0.006
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0168 0.0168
Plasmodium vivax hexose transporter 0.0103 0.0124 0.0442
Plasmodium falciparum plasmepsin III 0.0019 0.0006 0.0033
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.01 0.0121 0.0121
Leishmania major glucose transporter, lmgt2 0.0032 0.0025 0.007
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Loa Loa (eye worm) hypothetical protein 0.0423 0.0577 0.0577
Trypanosoma brucei proteasome beta 7 subunit 0.0018 0.0005 0.0014
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0018 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.002 0.0203
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0024 0.0127
Trypanosoma cruzi calpain cysteine peptidase, putative 0.058 0.0798 0.0798
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Brugia malayi hypothetical protein 0.0042 0.0039 0.0039
Leishmania major calpain family cysteine protease-like protein 0.058 0.0798 0.2285
Leishmania major glucose transporter, lmgt1 0.0032 0.0025 0.007
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.004 0.0115
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0018 0.0018
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Plasmodium falciparum plasmepsin VIII, putative 0.0019 0.0006 0.0033
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0044 0.0041 0.0041
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0024 0.0087
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0297 0.0399 0.0399
Toxoplasma gondii calmodulin, putative 0.0027 0.0018 0.005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.002 0.002
Toxoplasma gondii prolyl endopeptidase 0.1711 0.2393 0.6856
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0035 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0018 0.0005 0.0005
Plasmodium vivax vivapain-2 0.1381 0.1927 0.6846
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0039 0.0039
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0423 0.0577 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0423 0.0577 0.1652
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0011 0.0023
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0423 0.0577 0.2866
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.058 0.0798 0.0798
Trypanosoma cruzi metacaspase, putative 0.0043 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.002 0.0093
Loa Loa (eye worm) hypothetical protein 0.014 0.0178 0.0178
Schistosoma mansoni cathepsin F (C01 family) 0.0993 0.138 0.138
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0005 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Trichomonas vaginalis calcium binding protein, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0116 0.0116
Brugia malayi Cathepsin L-like precursor 0.1381 0.1927 0.1927
Echinococcus granulosus dnaJ subfamily B 0.0828 0.1148 0.1148
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0021 0.0021
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.001 0.0024
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Entamoeba histolytica hypothetical protein 0.0023 0.0012 0.0036
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0011 0.0011
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0018 0.0005 0.0005
Onchocerca volvulus 0.0423 0.0577 0.1216
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0027
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0423 0.0577 0.1652
Giardia lamblia Cathepsin L-like protease 0.0423 0.0577 0.1652
Mycobacterium ulcerans beta-lactamase 0.0039 0.0035 0.0366
Plasmodium falciparum calpain 0.058 0.0798 0.4139
Trichomonas vaginalis kakapo, putative 0.0027 0.0018 0.005
Trypanosoma brucei mitochondrial calcium uptake 1 0.0316 0.0426 0.1219
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0079 0.0079
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0018 0.0005 0.0005
Onchocerca volvulus Peroxidasin homolog 0.0104 0.0126 0.0267
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0018 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.002 0.0203
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0423 0.0577 0.2049
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0024 0.0024
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0811 0.1124 0.1124
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0115 0.0115
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0018 0.0005 0.0025
Echinococcus multilocularis cathepsin L cysteine protease 0.1381 0.1927 0.1927
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.002 0.0093
Schistosoma mansoni peroxidasin 0.0104 0.0126 0.0126
Echinococcus multilocularis proteasome subunit alpha type 2 0.0018 0.0005 0.0005
Schistosoma mansoni calpain-7 (C02 family) 0.2013 0.282 0.282
Schistosoma mansoni neprilysin-2 (M13 family) 0.0047 0.0047 0.0047
Brugia malayi cathepsin Z-like cysteine proteinase 0.0423 0.0577 0.0577
Mycobacterium tuberculosis Conserved protein 0.0174 0.0226 0.1073
Echinococcus multilocularis microtubule associated protein 2 0.2185 0.3062 0.3062
Mycobacterium ulcerans proteasome PrcB 0.0091 0.0107 0.1115
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0005 0.0005
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0012 0.0034
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0318 0.0429 0.0429
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.3956 0.5561 0.5561
Onchocerca volvulus 0.0993 0.138 0.291
Brugia malayi PAN domain containing protein 0.0029 0.0021 0.0021
Loa Loa (eye worm) cytochrome P450 0.0028 0.002 0.002
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0039 0.0039
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0015 0.0044
Echinococcus granulosus glycogen phosphorylase 0.0111 0.0136 0.0136
Giardia lamblia Proteasome subunit beta type 1 0.007 0.0079 0.0226
Brugia malayi hypothetical protein 0.0261 0.0348 0.0348
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0005 0.0014
Echinococcus multilocularis EF hand domain containing family member A2 0.0316 0.0426 0.0426
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.01 0.0121 0.0121
Echinococcus multilocularis calcyphosin protein 0.0027 0.0018 0.0018
Schistosoma mansoni inositol monophosphatase 0.0036 0.0031 0.0031
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0015 0.0054
Echinococcus granulosus expressed protein 0.0815 0.113 0.113
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.5702 0.8024 0.8024
Onchocerca volvulus 0.1381 0.1927 0.4064
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0023 0.0023
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0091 0.0107 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.002 0.0093
Leishmania major phospholipase c-like protein 0.0316 0.0426 0.1219
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0113 0.0325
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1381 0.1927 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0007 0.0038
Echinococcus granulosus calpain 7 C02 family 0.201 0.2815 0.2815
Loa Loa (eye worm) cathepsin B 0.2489 0.3491 0.3491
Brugia malayi cathepsin F-like cysteine proteinase 0.0388 0.0527 0.0527
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0423 0.0577 0.2049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Brugia malayi calpain D 0.058 0.0798 0.0798
Schistosoma mansoni cathepsin B (C01 family) 0.0423 0.0577 0.0577
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0018 0.0005 0.0005
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0252 0.0335 0.1593
Plasmodium vivax plasmepsin IV, putative 0.0019 0.0006 0.0022
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0297 0.0399 0.1143
Mycobacterium tuberculosis Hypothetical protein 0.0174 0.0226 0.1073
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0011 0.0011
Giardia lamblia Encystation-specific protease 0.0423 0.0577 0.1652
Loa Loa (eye worm) hypothetical protein 0.0388 0.0527 0.0527
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0005 0.0005
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0015 0.0044
Entamoeba histolytica calpain family cysteine protease, putative 0.058 0.0798 0.3974
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Echinococcus multilocularis Tolloid protein 1 0.0047 0.0046 0.0046
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0035 0.0168
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.002 0.0203
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0035 0.0101
Schistosoma mansoni hypothetical protein 0.0045 0.0044 0.0044
Brugia malayi proteasome subunit alpha type 6 0.0018 0.0005 0.0005
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0536 0.0736 0.1551
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0024 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0011 0.0011
Toxoplasma gondii preprocathepsin c precursor, putative 0.0423 0.0577 0.1652
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0018 0.005
Loa Loa (eye worm) hypothetical protein 0.0423 0.0577 0.0577
Echinococcus granulosus calumenin 0.0321 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0297 0.0399 0.1143
Echinococcus multilocularis apoptotic protease activating factor 1 0.0134 0.0169 0.0169
Toxoplasma gondii cathepsin CPC2 0.0423 0.0577 0.1652
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0013 0.0013
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0035 0.0168
Loa Loa (eye worm) hypothetical protein 0.01 0.0121 0.0121
Toxoplasma gondii aspartyl protease 0.0019 0.0006 0.0018
Echinococcus multilocularis hypothetical protein 0.201 0.2815 0.2815
Plasmodium falciparum serine repeat antigen 8 0.0423 0.0577 0.2992
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0091 0.0107 0.0515
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0018 0.0005 0.0014
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Toxoplasma gondii microneme protein MIC4 0.0029 0.0021 0.006
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.201 0.2815 0.2815
Trypanosoma brucei glucose transporter, putative 0.0032 0.0025 0.007
Echinococcus multilocularis geminin 0.0166 0.0214 0.0214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Trypanosoma cruzi metacaspase, putative 0.0043 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0993 0.138 0.3952
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0018 0.0005 0.0023
Toxoplasma gondii centrin, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Trypanosoma brucei metacaspase 0.0043 0.004 0.0115
Onchocerca volvulus 0.0039 0.0035 0.0074
Brugia malayi hypothetical protein 0.0104 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0092 0.011 0.011
Brugia malayi Trypsin family protein 0.01 0.0121 0.0121
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0205 0.0269 0.077
Entamoeba histolytica hypothetical protein 0.0035 0.0029 0.0124
Giardia lamblia Hypothetical protein 0.0174 0.0226 0.0647
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.002 0.0093
Trypanosoma cruzi calmodulin, putative 0.0316 0.0426 0.0426
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0048 0.0047 0.0224
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Brugia malayi prolyl oligopeptidase family protein 0.0297 0.0399 0.0399
Trypanosoma cruzi kinesin, putative 0.143 0.1997 0.1997
Echinococcus multilocularis cysteine protease 0.1381 0.1927 0.1927
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0423 0.0577 0.1652
Echinococcus granulosus apoptotic protease activating factor 1 0.0134 0.0169 0.0169
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0035 0.0318
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.004 0.0115
Entamoeba histolytica protein kinase, putative 0.0032 0.0024 0.0099
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0126 0.0126
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0018 0.0005 0.0005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0035 0.0035
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0007 0.0021
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1381 0.1927 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0811 0.1124 0.561
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0018 0.0005 0.0017
Plasmodium falciparum plasmepsin V 0.0019 0.0006 0.0033
Brugia malayi Trypsin family protein 0.01 0.0121 0.0121
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0044 0.0042 0.0042
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0011 0.0011
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0005 0.0005
Trypanosoma cruzi centrin, putative 0.0343 0.0464 0.0464
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0005 0.0005
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0018 0.0005 0.0017
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0011 0.0011
Leishmania major proteasome alpha 1 subunit, putative 0.0018 0.0005 0.0014
Echinococcus multilocularis enteropeptidase 0.01 0.0121 0.0121
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.01 0.0121 0.0121
Entamoeba histolytica cysteine protease, putative 0.0423 0.0577 0.2866
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0423 0.0577 0.2049
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.004 0.0115
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0018 0.0005 0.0014
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.8064
Echinococcus multilocularis calmodulin 0.0316 0.0426 0.0426
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0007 0.0007
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0018 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0316 0.0426 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0027
Plasmodium falciparum proline--tRNA ligase 0.0036 0.003 0.0157
Brugia malayi Cam kinase protein 1 0.0032 0.0024 0.0024
Plasmodium vivax vivapain-1 0.0811 0.1124 0.3994
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Brugia malayi hypothetical protein 0.0042 0.0039 0.0039
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0013 0.0038
Leishmania major hypothetical protein, unknown function 0.058 0.0798 0.2285
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0007 0.0007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.7103 1 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0039
Giardia lamblia Cathepsin L-like protease 0.0423 0.0577 0.1652
Trypanosoma brucei calpain-like protein, putative 0.201 0.2815 0.8064
Toxoplasma gondii calcium-dependent protein kinase 0.0323 0.0435 0.1247
Schistosoma mansoni reticulocalbin 0.0321 0.0432 0.0432
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.1927 0.1927
Trypanosoma cruzi calmodulin, putative 0.0316 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0205 0.0269 0.0269
Echinococcus granulosus inhibitor of apoptosis protein 0.0177 0.023 0.023
Schistosoma mansoni cathepsin s 0.0388 0.0527 0.0527
Onchocerca volvulus Cathepsin F homolog 0.1381 0.1927 0.4064
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0126 0.0126
Leishmania major calmodulin, putative 0.0316 0.0426 0.1219
Echinococcus granulosus proteasome prosome macropain subunit beta 0.007 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.1927 0.5521
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.001 0.0027
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.001 0.001
Onchocerca volvulus Deterin homolog 0.0177 0.023 0.0485
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0039 0.0039
Echinococcus multilocularis Glycosyl transferase, family 35 0.0111 0.0136 0.0136
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0039 0.0111
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.5702 0.8024 0.8024
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0035 0.0168
Entamoeba histolytica protein kinase, putative 0.0032 0.0024 0.0099
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.002 0.0056
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.058 0.0798 0.0798
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0047 0.0047
Schistosoma mansoni memapsin-2 (A01 family) 0.0471 0.0643 0.0643
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0016
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0018 0.0005 0.0025
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0423 0.0577 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0423 0.0577 0.1652
Entamoeba histolytica hypothetical protein, conserved 0.0321 0.0432 0.2141
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.0113 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1483 0.2072 0.5936
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0018 0.0005 0.0014
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0047 0.0213
Echinococcus granulosus glycogen phosphorylase 0.0111 0.0136 0.0136
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0044 0.0041 0.0118
Loa Loa (eye worm) hypothetical protein 0.01 0.0121 0.0121
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0012 0.0124
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0024 0.0024
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.058 0.0798 0.2285
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.201 0.2815 0.2815
Brugia malayi Cytochrome P450 family protein 0.0028 0.002 0.002
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0124 0.0124
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.201 0.2815 0.2815
Echinococcus granulosus gamma secretase subunit aph 1 0.028 0.0375 0.0375
Trypanosoma brucei Calpain-like protein 1.1 0.058 0.0798 0.2285
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0005 0.0005
Toxoplasma gondii protein kinase, putative 0.029 0.0389 0.1115
Brugia malayi Papain family cysteine protease containing protein 0.0811 0.1124 0.1124
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0031 0.0031
Schistosoma mansoni gamma-secretase subunit aph-1 0.028 0.0375 0.0375
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.002 0.0203
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0011 0.0011
Brugia malayi Cytochrome P450 family protein 0.0047 0.0047 0.0047
Trypanosoma brucei cytochrome P450, putative 0.0047 0.0047 0.0133
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.001 0.0024
Entamoeba histolytica prolyl oligopeptidase family protein 0.0205 0.0269 0.1323
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.001 0.001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.2285
Echinococcus granulosus proteasome subunit beta type 7 0.0018 0.0005 0.0005
Trichomonas vaginalis caltractin, putative 0.0027 0.0018 0.005
Plasmodium vivax aspartyl protease, putative 0.0019 0.0006 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0316 0.0426 0.1219
Schistosoma mansoni cercarial elastase (S01 family) 0.01 0.0121 0.0121
Leishmania major proteasome beta 5 subunit, putative 0.0091 0.0107 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0025 0.007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.3376 0.4742 0.4742
Brugia malayi hypothetical protein 0.0035 0.0029 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0012 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0423 0.0577 0.1652
Brugia malayi aspartic protease BmAsp-2, identical 0.0019 0.0006 0.0006
Schistosoma mansoni ef hand domain family member A2 0.0316 0.0426 0.0426
Leishmania major hypothetical protein, conserved 0.058 0.0798 0.2285
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0316 0.0426 0.0426
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0005 0.0014
Onchocerca volvulus 0.01 0.0121 0.0256
Trichomonas vaginalis calpain, putative 0.058 0.0798 0.2285
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0104 0.0127 0.0127
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0698 0.0964 1
Brugia malayi Protein kinase domain containing protein 0.0045 0.0044 0.0044
Schistosoma mansoni microtubule-associated protein tau 0.2185 0.3062 0.3062
Leishmania major centrin, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Mycobacterium leprae probable zinc metalloprotease 0.0094 0.0112 0.1123
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0018 0.0005 0.0017
Loa Loa (eye worm) hypothetical protein 0.0104 0.0126 0.0126
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Leishmania major cathepsin L-like protease 0.1381 0.1927 0.5521
Loa Loa (eye worm) calpain D 0.058 0.0798 0.0798
Echinococcus multilocularis proteasome subunit beta type 6 0.0018 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.0269 0.077
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.002 0.0203
Trichomonas vaginalis calmodulin, putative 0.0316 0.0426 0.1219
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0018 0.0005 0.0025
Mycobacterium ulcerans proteasome PrcA 0.0018 0.0005 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0011 0.0011
Toxoplasma gondii peptidase c13 family protein 0.014 0.0178 0.0509
Echinococcus granulosus Glycosyl transferase family 35 0.0111 0.0136 0.0136
Entamoeba histolytica cysteine protease, putative 0.0811 0.1124 0.561
Leishmania major hypothetical protein, conserved 0.0321 0.0432 0.1237
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0048 0.0047 0.049
Onchocerca volvulus 0.0026 0.0017 0.0036
Schistosoma mansoni glucose transport protein 0.0103 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0045 0.0044 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0423 0.0577 0.1652
Trypanosoma cruzi cysteine protease, putative 0.0811 0.1124 0.1124
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.003 0.0087
Loa Loa (eye worm) glycogen phosphorylase 0.0111 0.0136 0.0136
Echinococcus granulosus EF hand domain containing family member A2 0.0316 0.0426 0.0426
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.058 0.0798 0.0798
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0021 0.0021
Brugia malayi hypothetical protein 0.0313 0.0422 0.0422
Leishmania major protein kinase, putative 0.0318 0.0429 0.1228
Plasmodium falciparum plasmepsin X 0.0019 0.0006 0.0033
Loa Loa (eye worm) hypothetical protein 0.0313 0.0422 0.0422
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.014 0.0178 0.0509
Onchocerca volvulus 0.0029 0.0021 0.0044
Schistosoma mansoni glycogen phosphorylase 0.0111 0.0136 0.0136
Plasmodium falciparum plasmepsin IX 0.0019 0.0006 0.0033
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0039 0.0039
Trichomonas vaginalis calmodulin, putative 0.0316 0.0426 0.1219
Echinococcus granulosus lamin dm0 0.0026 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0166 0.0214 0.0214
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0297 0.0399 0.0399
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0423 0.0577 0.2992
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Echinococcus multilocularis cathepsin L 0.0811 0.1124 0.1124
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0039 0.0039
Trichomonas vaginalis calmodulin, putative 0.0316 0.0426 0.1219
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0039 0.0039
Plasmodium vivax centrin-1, putative 0.0316 0.0426 0.1512
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.0018
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0018 0.0005 0.0005
Plasmodium falciparum centrin-1 0.0316 0.0426 0.2208
Brugia malayi PXA domain containing protein 0.0042 0.0039 0.0039
Plasmodium falciparum cysteine proteinase falcipain 1 0.0811 0.1124 0.5833
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.002 0.0203
Schistosoma mansoni rab 0.0316 0.0426 0.0426
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.002 0.0093
Schistosoma mansoni reticulocalbin 0.0316 0.0426 0.0426
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0031 0.0031
Brugia malayi proteasome subunit alpha type 4 0.0018 0.0005 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0205 0.0269 0.0955
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0021 0.001 0.0027
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0035 0.0101
Leishmania major oligopeptidase b 0.0698 0.0964 0.2761
Echinococcus multilocularis cathepsin L cysteine protease 0.1381 0.1927 0.1927
Echinococcus multilocularis prolyl endopeptidase 0.1711 0.2393 0.2393

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.402 Inhibition of aromatase ChEMBL. 20638757
IC50 (binding) = 56 nM In vitro inhibitory concentration against human CYP11B2 expressed in V79MZh hamster fibroblasts incubated with 100 nM of substrate deoxycorticosterone in presence of the compound ChEMBL. 15743198
IC50 (binding) = 56 nM In vitro inhibitory concentration against human CYP11B2 expressed in V79MZh hamster fibroblasts incubated with 100 nM of substrate deoxycorticosterone in presence of the compound ChEMBL. 15743198
IC50 (binding) = 484 nM In vitro inhibitory concentration against human CYP11B1 expressed in V79 MZh hamster fibroblasts incubated with 100 nM of substrate deoxycorticosterone in presence of the compound ChEMBL. 15743198
IC50 (binding) = 484 nM In vitro inhibitory concentration against human CYP11B1 expressed in V79 MZh hamster fibroblasts incubated with 100 nM of substrate deoxycorticosterone in presence of the compound ChEMBL. 15743198
IC50 (binding) = 3400 nM In vitro inhibitory concentration against human placental CYP19 incubated with 500 nM of substrate androstenedione in presence of the compound ChEMBL. 15743198
IC50 (binding) = 3400 nM In vitro inhibitory concentration against human placental CYP19 incubated with 500 nM of substrate androstenedione in presence of the compound ChEMBL. 15743198
IC50 (binding) = 3.96 uM Inhibition of aromatase ChEMBL. 20638757
Inhibition (binding) = 40 % In vitro inhibition of human CYP11B2 expressed in Schizosaccharomyces pombe incubated with 100 nM of substrate deoxycorticosterone in presence of 500 nM of compound ChEMBL. 15743198
Inhibition (binding) = 40 % In vitro inhibition of human CYP11B2 expressed in Schizosaccharomyces pombe incubated with 100 nM of substrate deoxycorticosterone in presence of 500 nM of compound ChEMBL. 15743198
Inhibition (binding) = 877 % In vitro inhibition of human CYP17 expressed in Escherichia coli incubated with 2.5 uM of substrate progesterone in presence of 2.5 uM of compound ChEMBL. 15743198
Inhibition (binding) = 877 % In vitro inhibition of human CYP17 expressed in Escherichia coli incubated with 2.5 uM of substrate progesterone in presence of 2.5 uM of compound ChEMBL. 15743198
Selectivity ratio (binding) = 1.8 In vitro IC50 ratio of the compound against human CYP11B1 to that of human CYP11B2 ChEMBL. 15743198

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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