Detailed information for compound 314189

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 356.498 | Formula: C23H32O3
  • H donors: 2 H acceptors: 3 LogP: 4.1 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(=O)CC[C@@H]1CC2(C)C(O)CCC2C2C1c1ccc(cc1CC2)O
  • InChi: 1S/C23H32O3/c1-3-16(24)6-4-15-13-23(2)20(10-11-21(23)26)19-8-5-14-12-17(25)7-9-18(14)22(15)19/h7,9,12,15,19-22,25-26H,3-6,8,10-11,13H2,1-2H3/t15-,19?,20?,21?,22?,23?/m0/s1
  • InChiKey: OPHZDRYBOFJDHR-BFDXXNCGSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax vivapain-3 0.0408 0.1148 0.4072
Onchocerca volvulus 0.0058 0.0071 0.0135
Echinococcus granulosus EF hand domain containing family member A2 0.014 0.0324 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0207 0.053 0.1517
Giardia lamblia Alanyl dipeptidyl peptidase 0.0081 0.0142 0.0357
Echinococcus multilocularis cathepsin b 0.3279 1 1
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Echinococcus multilocularis calmodulin 0.0139 0.0319 0.0314
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0702 0.2056 0.2056
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0041 0.0019 0.0046
Echinococcus multilocularis hypothetical protein 0.0947 0.2812 0.2807
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0067 0.0099 0.0268
Plasmodium falciparum serine repeat antigen 6 0.0207 0.053 0.2508
Toxoplasma gondii centrin, putative 0.0139 0.0319 0.0907
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.053 0.1517
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0379 0.1059 0.1059
Toxoplasma gondii centrin 0.0139 0.0319 0.0907
Trichomonas vaginalis calmodulin, putative 0.0139 0.0319 0.0907
Leishmania major proteasome beta 5 subunit, putative 0.015 0.0354 0.1007
Plasmodium falciparum plasmepsin IX 0.0276 0.0741 0.3547
Schistosoma mansoni integrin alpha 0.0151 0.0356 0.0356
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Plasmodium falciparum serine repeat antigen 1 0.0207 0.053 0.2508
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.053 0.1517
Trypanosoma cruzi cysteine proteinase, putative 0.0408 0.1148 0.1143
Echinococcus multilocularis calpain 5 0.0947 0.2812 0.2807
Schistosoma mansoni calmodulin 0.0139 0.0319 0.0319
Leishmania major hypothetical protein, unknown function 0.0273 0.0734 0.2109
Trypanosoma cruzi caltractin, putative 0.0139 0.0319 0.0314
Trypanosoma cruzi I/6 autoantigen, putative 0.0139 0.0319 0.0314
Entamoeba histolytica cysteine protease, putative 0.0207 0.053 0.2508
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.0195 0.0189
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0273 0.0734 0.0728
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Trypanosoma cruzi major cysteine proteinase, putative 0.0207 0.053 0.0524
Schistosoma mansoni integrin beta subunit 0.0182 0.0452 0.0452
Brugia malayi hypothetical protein 0.0238 0.0624 0.0618
Echinococcus granulosus calcium uptake protein 1 0.014 0.0324 0.0319
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Entamoeba histolytica cysteine protease, putative 0.0207 0.053 0.2508
Trichomonas vaginalis conserved hypothetical protein 0.0139 0.0319 0.0907
Trypanosoma brucei proteasome subunit beta type-5, putative 0.015 0.0354 0.0766
Schistosoma mansoni cathepsin B (C01 family) 0.0207 0.053 0.053
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0081 0.0142 0.0298
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0073 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0207 0.053 0.1867
Brugia malayi Cathepsin L-like precursor 0.0702 0.2056 0.2051
Toxoplasma gondii hypothetical protein 0.0081 0.0142 0.0393
Brugia malayi calpain family protein 1 0.2539 0.7717 0.7715
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.053 0.1485
Plasmodium falciparum importin beta, putative 0.0056 0.0065 0.0224
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0947 0.2812 0.2807
Onchocerca volvulus Prolyl endopeptidase homolog 0.0545 0.1571 0.3268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Echinococcus multilocularis cysteine protease 0.0702 0.2056 0.2051
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0168 0.0409 0.0404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Plasmodium vivax SET domain protein, putative 0.0058 0.0071 0.023
Onchocerca volvulus 0.0139 0.0319 0.0654
Trichomonas vaginalis calmodulin-2, putative 0.0139 0.0319 0.0907
Loa Loa (eye worm) hypothetical protein 0.0501 0.1437 0.1437
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0319 0.0319
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2677 0.8144 0.8143
Echinococcus granulosus cysteine protease 0.0408 0.1148 0.1143
Entamoeba histolytica hypothetical protein, conserved 0.0081 0.0142 0.0603
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.8126
Trichomonas vaginalis calcium binding protein, putative 0.0139 0.0319 0.0907
Brugia malayi Cytochrome P450 family protein 0.0047 0.0037 0.0031
Trypanosoma cruzi centrin, putative 0.0146 0.0341 0.0336
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.1437 0.6963
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0273 0.0734 0.0728
Brugia malayi Animal haem peroxidase family protein 0.0238 0.0624 0.0618
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Brugia malayi gamma-secretase subunit aph-1 0.0252 0.0669 0.0664
Loa Loa (eye worm) hypothetical protein 0.0058 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0047 0.0036 0.0036
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.015 0.0354 0.1644
Plasmodium vivax aspartyl protease, putative 0.0276 0.0741 0.2621
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0247 0.0247
Echinococcus granulosus neurocalcin 0.0139 0.0319 0.0314
Onchocerca volvulus Chorion peroxidase homolog 0.0238 0.0624 0.129
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0041 0.0019 0.0028
Entamoeba histolytica cysteine protease, putative 0.0207 0.053 0.2508
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0233 0.0609 1
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0081 0.0142 0.0393
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Leishmania major hypothetical protein, conserved 0.0273 0.0734 0.2109
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0207 0.053 0.1867
Trypanosoma brucei protein I/6 0.0139 0.0319 0.069
Giardia lamblia Cathepsin B precursor 0.0207 0.053 0.1485
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Brugia malayi calpain 5 0.0674 0.1969 0.1964
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0408 0.1148 0.1143
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.053 0.1517
Schistosoma mansoni calpain C (C02 family) 0.0947 0.2812 0.2812
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Trypanosoma cruzi major cysteine proteinase, putative 0.0207 0.053 0.0524
Trypanosoma cruzi cysteine protease, putative 0.0408 0.1148 0.1143
Loa Loa (eye worm) hypothetical protein 0.0037 0.0006 0.0006
Echinococcus granulosus cathepsin L cysteine protease 0.0408 0.1148 0.1143
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0026 0.0026
Giardia lamblia Cathepsin L precursor 0.0207 0.053 0.1485
Echinococcus multilocularis calumenin 0.014 0.0324 0.0319
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0073 0.0067
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0207 0.053 0.053
Onchocerca volvulus Cathepsin F homolog 0.0702 0.2056 0.4279
Giardia lamblia Cathepsin L precursor 0.0207 0.053 0.1485
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0207 0.053 0.2508
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.0623 0.4692
Trypanosoma brucei hypothetical protein 0.0273 0.0734 0.1602
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0207 0.053 0.1867
Onchocerca volvulus 0.0702 0.2056 0.4279
Onchocerca volvulus Peroxidase homolog 0.0238 0.0624 0.129
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.015 0.0354 0.0354
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0064 0.0058
Giardia lamblia Cathepsin L precursor 0.0207 0.053 0.1485
Loa Loa (eye worm) fibroinase 0.0702 0.2056 0.2056
Entamoeba histolytica calpain large subunit domain III containing protein 0.0674 0.1969 0.9575
Trypanosoma brucei Component of motile flagella 41 0.0139 0.0319 0.069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0408 0.1148 0.2514
Echinococcus multilocularis acylamino acid releasing enzyme 0.0081 0.0142 0.0136
Loa Loa (eye worm) hypothetical protein 0.0081 0.0142 0.0142
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0207 0.053 0.1867
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0037 0.0031
Trypanosoma brucei cysteine peptidase, putative 0.0273 0.0734 0.1602
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Mycobacterium leprae proteasome (beta subunit) PrcB 0.015 0.0354 0.5766
Plasmodium vivax serine-repeat antigen (SERA) 0.0207 0.053 0.1867
Entamoeba histolytica cysteine proteinase, putative 0.0408 0.1148 0.5545
Toxoplasma gondii calcium-dependent protein kinase 0.014 0.0324 0.0922
Onchocerca volvulus 0.0094 0.0182 0.0367
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0073 0.0073
Giardia lamblia Alanyl dipeptidyl peptidase 0.0081 0.0142 0.0357
Trichomonas vaginalis myosin light chain 1, putative 0.0139 0.0319 0.0907
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0058 0.0071 0.0187
Entamoeba histolytica cysteine proteinase 1, putative 0.0408 0.1148 0.5545
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Loa Loa (eye worm) hypothetical protein 0.0207 0.053 0.053
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0044 0.0026 0.0035
Brugia malayi Cathepsin L-like precursor 0.0201 0.051 0.0504
Leishmania major calmodulin-like protein 0.0139 0.0319 0.0907
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0037 0.0031
Brugia malayi calpain D 0.0273 0.0734 0.0728
Giardia lamblia Cathepsin B precursor 0.1157 0.3459 1
Echinococcus granulosus calbindin 32 0.014 0.0324 0.0319
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2677 0.8144 0.8143
Entamoeba histolytica hypothetical protein 0.0207 0.053 0.2508
Brugia malayi Kelch motif family protein 0.0047 0.0036 0.003
Echinococcus granulosus gamma secretase subunit aph 1 0.0252 0.0669 0.0664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0207 0.053 0.1867
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0207 0.053 0.1867
Leishmania major importin beta-1 subunit, putative 0.0046 0.0032 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Trichomonas vaginalis calcium binding proteins, putative 0.0139 0.0319 0.0907
Loa Loa (eye worm) beta-lactamase 0.0037 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Echinococcus multilocularis centrin 2 0.0139 0.0319 0.0314
Loa Loa (eye worm) hypothetical protein 0.0273 0.0734 0.0734
Entamoeba histolytica calcium-binding protein, putative 0.0139 0.0319 0.1475
Echinococcus granulosus programmed cell death protein 0.0146 0.0341 0.0336
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0273 0.0734 0.2109
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0081 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.053 0.1517
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0139 0.0319 0.0907
Loa Loa (eye worm) hypothetical protein 0.0081 0.0142 0.0142
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.053 0.053
Brugia malayi hypothetical protein 0.0462 0.1314 0.1309
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0201 0.051 0.051
Schistosoma mansoni cathepsin F (C01 family) 0.0702 0.2056 0.2056
Trypanosoma brucei kinesin, putative 0.0674 0.1969 0.4321
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0392 0.1101 0.1096
Loa Loa (eye worm) cysteine protease 0.0702 0.2056 0.2056
Brugia malayi prolyl oligopeptidase family protein 0.0392 0.1101 0.1096
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0139 0.0319 0.0314
Trichomonas vaginalis calcineurin B subunit, putative 0.014 0.0324 0.0922
Trypanosoma brucei calmodulin, putative 0.014 0.0324 0.0701
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0081 0.0142 0.0393
Trypanosoma brucei oligopeptidase b 0.0233 0.0609 0.1328
Leishmania major calmodulin-like protein 0.0139 0.0319 0.0907
Echinococcus granulosus snurportin 1 0.0599 0.1739 0.1734
Giardia lamblia Cathepsin L-like protease 0.0207 0.053 0.1485
Giardia lamblia Cysteine protease 0.0207 0.053 0.1485
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0319 0.0319
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0032 0.0075
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0073 0.0195
Echinococcus granulosus cathepsin L 0.0207 0.053 0.0524
Brugia malayi Blistered cuticle protein 3 0.0238 0.0624 0.0618
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0139 0.0319 0.069
Loa Loa (eye worm) EF hand family protein 0.0139 0.0319 0.0319
Entamoeba histolytica cysteine proteinase, putative 0.0408 0.1148 0.5545
Echinococcus granulosus acylamino acid releasing enzyme 0.0081 0.0142 0.0136
Entamoeba histolytica hypothetical protein 0.0046 0.0032 0.0064
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0067 0.0099 0.0268
Echinococcus multilocularis integrin alpha 3 0.0116 0.0248 0.0242
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.015 0.0354 0.1007
Plasmodium vivax proteasome subunit beta type-5, putative 0.015 0.0354 0.124
Echinococcus granulosus calmodulin 0.0139 0.0319 0.0314
Entamoeba histolytica cysteine proteinase, putative 0.0408 0.1148 0.5545
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0139 0.0319 0.0314
Plasmodium vivax unspecified product 0.0201 0.051 0.1797
Schistosoma mansoni hypothetical protein 0.0273 0.0734 0.0734
Schistosoma mansoni reticulocalbin 0.0139 0.0319 0.0319
Brugia malayi Pre-SET motif family protein 0.0405 0.114 0.1135
Echinococcus multilocularis programmed cell death protein 0.0146 0.0341 0.0336
Schistosoma mansoni calmodulin related calcium binding protein 0.0139 0.0319 0.0319
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0041 0.0019 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Schistosoma mansoni Mername-AA248 (C02 family) 0.0947 0.2812 0.2812
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.0734 0.2109
Trichomonas vaginalis hypothetical protein 0.0273 0.0734 0.2109
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0139 0.0319 0.0314
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0058 0.0071 0.0071
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0947 0.2812 0.6176
Loa Loa (eye worm) proteasome subunit beta type 1 0.0067 0.0099 0.0099
Onchocerca volvulus 0.0139 0.0319 0.0654
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3279 1 1
Giardia lamblia Cathepsin L precursor 0.0207 0.053 0.1485
Schistosoma mansoni centrin-related 0.0139 0.0319 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Trypanosoma brucei Calpain-like protein CALP1.3 0.0273 0.0734 0.1602
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0065 0.0059
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0273 0.0734 0.0728
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.015 0.0354 0.0348
Schistosoma mansoni cathepsin C 0.0207 0.053 0.053
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2812 0.6176
Trypanosoma brucei Calpain-like protein 1.2 0.0273 0.0734 0.1602
Echinococcus multilocularis calcium uptake protein 1 0.014 0.0324 0.0319
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0233 0.0609 0.0604
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0044 0.0026 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0037 0.0037
Schistosoma mansoni calpain-2 (C02 family) 0.0273 0.0734 0.0734
Toxoplasma gondii proteasome subunit beta type, putative 0.015 0.0354 0.1007
Toxoplasma gondii cathepsin B 0.1157 0.3459 1
Brugia malayi Animal haem peroxidase family protein 0.0238 0.0624 0.0618
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0379 0.1059 0.1054
Brugia malayi Cathepsin L-like precursor 0.0702 0.2056 0.2051
Brugia malayi Pre-SET motif family protein 0.0058 0.0071 0.0065
Giardia lamblia Cathepsin L precursor 0.0207 0.053 0.1485
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0207 0.053 0.1867
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Brugia malayi prolyl oligopeptidase family protein 0.0168 0.0409 0.0404
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.014 0.0324 0.0319
Entamoeba histolytica calpain family cysteine protease, putative 0.0273 0.0734 0.3511
Loa Loa (eye worm) hypothetical protein 0.2265 0.6874 0.6874
Onchocerca volvulus Cathepsin L homolog 0.0702 0.2056 0.4279
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.1602
Loa Loa (eye worm) hypothetical protein 0.0037 0.0006 0.0006
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0081 0.0142 0.0393
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2812 0.2807
Loa Loa (eye worm) hypothetical protein 0.1591 0.4796 0.4796
Echinococcus granulosus importin subunit beta 1 0.0056 0.0065 0.0059
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0408 0.1148 0.1148
Echinococcus granulosus centrin 2 0.0139 0.0319 0.0314
Trypanosoma cruzi cysteine peptidase, putative 0.0408 0.1148 0.1143
Brugia malayi Integrin beta pat-3 precursor 0.0309 0.0843 0.0838
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0073 0.1114
Loa Loa (eye worm) hypothetical protein 0.0207 0.053 0.053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3279 1 1
Echinococcus granulosus calpain 5 0.0947 0.2812 0.2807
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0026 0.0058
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.8126
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0067 0.0099 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0408 0.1148 0.2514
Entamoeba histolytica prolyl oligopeptidase family protein 0.0081 0.0142 0.0603
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0142 0.0136
Loa Loa (eye worm) calpain family protein 1 0.1865 0.5639 0.5639
Schistosoma mansoni calpain-7 (C02 family) 0.095 0.2821 0.2821
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0273 0.0734 0.2109
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0067 0.0099 0.0268
Loa Loa (eye worm) calmodulin-like protein 0.0139 0.0319 0.0319
Trypanosoma brucei caltractin, putative 0.0146 0.0341 0.0738
Echinococcus multilocularis snurportin 1 0.0599 0.1739 0.1734
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0207 0.053 0.1517
Echinococcus multilocularis calpain family protein 1, d 0.1865 0.5639 0.5636
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0071 0.0071
Plasmodium vivax centrin-1, putative 0.0139 0.0319 0.1117
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0006 0.0006
Trypanosoma brucei Calpain-like protein 1.1 0.0273 0.0734 0.1602
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0273 0.0734 0.1602
Plasmodium vivax vivapain-1 0.0408 0.1148 0.4072
Echinococcus multilocularis cysteine protease 0.0702 0.2056 0.2051
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0041 0.0019 0.0037
Plasmodium falciparum serine repeat antigen 5 0.0207 0.053 0.2508
Entamoeba histolytica calmodulin, putative 0.0139 0.0319 0.1475
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Schistosoma mansoni gamma-secretase subunit aph-1 0.0252 0.0669 0.0669
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0139 0.0319 0.1475
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0037 0.0037
Giardia lamblia Cathepsin B precursor 0.0207 0.053 0.1485
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0273 0.0734 0.2109
Echinococcus granulosus GTP binding nuclear protein Ran 0.0041 0.0019 0.0013
Toxoplasma gondii troponin c, isotype gamma, putative 0.0139 0.0319 0.0907
Echinococcus multilocularis integrin alpha ps 0.0068 0.01 0.0094
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0273 0.0734 0.2109
Entamoeba histolytica cysteine proteinase 2 0.0408 0.1148 0.5545
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.1602
Loa Loa (eye worm) integrin alpha pat-2 0.0232 0.0608 0.0608
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0168 0.0409 0.0888
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Echinococcus multilocularis programmed cell death protein 0.0146 0.0341 0.0336
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0702 0.2056 0.2051
Trichomonas vaginalis calmodulin, putative 0.0146 0.0341 0.0971
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0058 0.0071 0.0065
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0099 0.0093
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.0247 0.0247
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0065 0.0129
Entamoeba histolytica cysteine protease, putative 0.0702 0.2056 1
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0273 0.0734 0.1602
Echinococcus multilocularis EF hand domain containing family member A2 0.014 0.0324 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0702 0.2056 0.5937
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.053 0.1517
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0207 0.053 0.1517
Echinococcus granulosus calpain 7 C02 family 0.0947 0.2812 0.2807
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0006 0.0006
Loa Loa (eye worm) calpain 5 0.0674 0.1969 0.1969
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.2056 0.2051
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Leishmania major calpain protease-like protein 0.0273 0.0734 0.2109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.053 0.1517
Brugia malayi calpain 7 0.0947 0.2812 0.2807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Brugia malayi cathepsin L precursor 0.0207 0.053 0.0524
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Echinococcus multilocularis prolyl endopeptidase 0.0545 0.1571 0.1566
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0081 0.0142 0.0603
Schistosoma mansoni hypothetical protein 0.0094 0.0182 0.0182
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2539 0.7717 0.7717
Plasmodium vivax proteasome subunit beta type-1, putative 0.0067 0.0099 0.033
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0019 0.0013
Leishmania major proteasome beta 2 subunit, putative 0.0044 0.0026 0.0058
Echinococcus multilocularis calpain 0.0947 0.2812 0.2807
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0207 0.053 0.053
Trichomonas vaginalis calmodulin, putative 0.0139 0.0319 0.0907
Entamoeba histolytica hypothetical protein, conserved 0.014 0.0324 0.15
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0041 0.0019 0.0019
Loa Loa (eye worm) integrin beta-2 0.0309 0.0843 0.0843
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0319 0.0319
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0044 0.0026 0.0058
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0207 0.053 0.1867
Entamoeba histolytica grainin 2 0.0146 0.0341 0.1583
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0032 0.0075
Leishmania major phospholipase c-like protein 0.0139 0.0319 0.0907
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0073 0.0511
Loa Loa (eye worm) calpain D 0.0273 0.0734 0.0734
Schistosoma mansoni ef hand domain family member A2 0.0139 0.0319 0.0319
Plasmodium falciparum cysteine proteinase falcipain 3 0.0702 0.2056 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2677 0.8144 0.8144
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0464 0.1321 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0501 0.1437 0.4145
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0073 0.0195
Toxoplasma gondii prolyl endopeptidase 0.0545 0.1571 0.4534
Plasmodium vivax unspecified product 0.0207 0.053 0.1867
Brugia malayi Papain family cysteine protease containing protein 0.0702 0.2056 0.2051
Schistosoma mansoni importin beta-1 0.0056 0.0065 0.0065
Onchocerca volvulus 0.0238 0.0624 0.129
Brugia malayi cathepsin L-like precursor 0.0501 0.1437 0.1432
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Loa Loa (eye worm) hypothetical protein 0.1865 0.5639 0.5639
Trypanosoma cruzi calmodulin, putative 0.0139 0.0319 0.0314
Echinococcus multilocularis neuronal calcium sensor 0.0139 0.0319 0.0314
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0032 0.0075
Brugia malayi Cathepsin L-like precursor 0.0501 0.1437 0.1432
Leishmania major calmodulin, putative 0.0139 0.0319 0.0907
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.2807
Brugia malayi hypothetical protein 0.0087 0.0159 0.0153
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0273 0.0734 0.0728
Brugia malayi prolyl oligopeptidase family protein 0.0545 0.1571 0.1566
Trypanosoma cruzi 20S proteasome subunit 0.0044 0.0026 0.002
Brugia malayi fibroinase precursor 0.0207 0.053 0.0524
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.053 0.1517
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0073 0.1114
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0273 0.0734 0.1602
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0139 0.0319 0.1475
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0139 0.0319 0.0319
Echinococcus granulosus cathepsin b 0.3279 1 1
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0168 0.0409 0.0404
Toxoplasma gondii cathepsin CPC2 0.0207 0.053 0.1517
Trypanosoma brucei cysteine peptidase C (CPC) 0.1157 0.3459 0.7599
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2812 0.2807
Trypanosoma cruzi oligopeptidase b 0.0233 0.0609 0.0604
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Brugia malayi Cathepsin L-like precursor 0.0702 0.2056 0.2051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Plasmodium vivax hypothetical protein, conserved 0.014 0.0324 0.1135
Leishmania major protein kinase, putative 0.0139 0.0319 0.0907
Echinococcus multilocularis integrin beta 2 0.0229 0.0597 0.0591
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.2056 0.2051
Trypanosoma cruzi oligopeptidase b 0.0233 0.0609 0.0604
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.053 0.053
Echinococcus granulosus neuronal calcium sensor 0.0139 0.0319 0.0314
Trichomonas vaginalis centrin, putative 0.0139 0.0319 0.0907
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0408 0.1148 0.1148
Leishmania major GTP-binding protein, putative 0.0041 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0087 0.0159 0.0159
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0273 0.0734 0.0728
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.053 0.1517
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.053 0.053
Brugia malayi MH2 domain containing protein 0.0115 0.0247 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.053 0.1517
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0168 0.0409 0.0409
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Echinococcus granulosus Dipeptidyl peptidase 9 0.0168 0.0409 0.0404
Leishmania major calpain family cysteine protease-like protein 0.0273 0.0734 0.2109
Trichomonas vaginalis calmodulin, putative 0.0139 0.0319 0.0907
Loa Loa (eye worm) hypothetical protein 0.0207 0.053 0.053
Schistosoma mansoni ran 0.0041 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0702 0.2056 1
Giardia lamblia Cathepsin B precursor 0.0207 0.053 0.1485
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.015 0.0354 0.2645
Leishmania major oligopeptidase b 0.0233 0.0609 0.1747
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0501 0.1437 0.4145
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0142 0.0136
Leishmania major cysteine peptidase A (CPA) 0.0702 0.2056 0.5937
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0273 0.0734 0.0728
Onchocerca volvulus 0.0702 0.2056 0.4279
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.6176
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0501 0.1437 0.1432
Trypanosoma cruzi I/6 autoantigen, putative 0.0139 0.0319 0.0314
Schistosoma mansoni ran 0.0041 0.0019 0.0019
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0168 0.0409 0.1168
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0056 0.0065 0.0065
Schistosoma mansoni calpain-7 (C02 family) 0.095 0.2821 0.2821
Schistosoma mansoni reticulocalbin 0.014 0.0324 0.0324
Giardia lamblia Cathepsin B precursor 0.1157 0.3459 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0037 0.0037
Onchocerca volvulus Cathepsin L homolog 0.0702 0.2056 0.4279
Echinococcus granulosus peroxidasin 0.0238 0.0624 0.0618
Schistosoma mansoni neuronal calcium sensor 0.0139 0.0319 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.053 0.1517
Brugia malayi cathepsin F-like cysteine proteinase 0.0201 0.051 0.0504
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0037 0.0031
Onchocerca volvulus 0.0238 0.0624 0.129
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0026 0.0058
Loa Loa (eye worm) hypothetical protein 0.0083 0.0148 0.0148
Brugia malayi Peroxidasin 0.0238 0.0624 0.0618
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0207 0.053 0.2508
Brugia malayi Angiotensin-converting enzyme family protein 0.0607 0.1763 0.1758
Trypanosoma brucei calpain, putative 0.0273 0.0734 0.1602
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Loa Loa (eye worm) hypothetical protein 0.0207 0.053 0.053
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0044 0.0026 0.002
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0207 0.053 0.1867
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0139 0.0319 0.0314
Plasmodium falciparum centrin-1 0.0139 0.0319 0.1475
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0139 0.0319 0.1117
Onchocerca volvulus Cathepsin L homolog 0.0207 0.053 0.1093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Toxoplasma gondii cathepsin CPC1 0.0207 0.053 0.1517
Echinococcus multilocularis survival motor neuron protein 1 0.0462 0.1314 0.1309
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0019 0.0013
Echinococcus multilocularis calpain A 0.2679 0.8149 0.8148
Trypanosoma cruzi calmodulin, putative 0.0139 0.0319 0.0314
Trypanosoma brucei centrin, putative 0.0139 0.0319 0.069
Leishmania major hypothetical protein, conserved 0.0139 0.0319 0.0907
Trichomonas vaginalis calmodulin, putative 0.0139 0.0319 0.0907
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1157 0.3459 1
Onchocerca volvulus Peroxidase homolog 0.0238 0.0624 0.129
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.2807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0702 0.2056 1
Leishmania major hypothetical protein, conserved 0.014 0.0324 0.0922
Leishmania major i/6 autoantigen-like protein 0.0139 0.0319 0.0907
Echinococcus granulosus calumenin 0.014 0.0324 0.0319
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0233 0.0609 0.1328
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2812 0.6176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.015 0.0354 0.0354
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Toxoplasma gondii EFHC1, putative 0.0139 0.0319 0.0907
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1157 0.3459 0.3455
Onchocerca volvulus 0.0702 0.2056 0.4279
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0139 0.0319 0.069
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0182 0.0176
Loa Loa (eye worm) hypothetical protein 0.0207 0.053 0.053
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0408 0.1148 0.1148
Brugia malayi Papain family cysteine protease containing protein 0.0408 0.1148 0.1143
Trichomonas vaginalis calmodulin, putative 0.014 0.0324 0.0922
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0207 0.053 0.053
Leishmania major centrin, putative 0.0139 0.0319 0.0907
Loa Loa (eye worm) hypothetical protein 0.0501 0.1437 0.1437
Plasmodium vivax unspecified product 0.0408 0.1148 0.4072
Loa Loa (eye worm) calpain 0.0947 0.2812 0.2812
Schistosoma mansoni cathepsin D (A01 family) 0.0316 0.0866 0.0866
Loa Loa (eye worm) hypothetical protein 0.0139 0.0319 0.0319
Trichomonas vaginalis calmodulin, putative 0.0139 0.0319 0.0907
Echinococcus multilocularis cathepsin b 0.3279 1 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0058 0.0071 0.0065
Entamoeba histolytica cysteine proteinase, putative 0.0702 0.2056 1
Loa Loa (eye worm) proteasome subunit beta type 2 0.0044 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0462 0.1314 0.1314
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.053 0.1517
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0207 0.053 0.053
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0207 0.053 0.053
Schistosoma mansoni calpain (C02 family) 0.0947 0.2812 0.2812
Trypanosoma brucei RNA helicase, putative 0.1511 0.4549 1
Mycobacterium ulcerans proteasome PrcB 0.015 0.0354 0.5766
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Brugia malayi cathepsin L-like cysteine proteinase 0.0207 0.053 0.0524
Echinococcus granulosus survival motor neuron protein 1 0.0462 0.1314 0.1309
Trichomonas vaginalis calmodulin, putative 0.0139 0.0319 0.0907
Plasmodium falciparum serine repeat antigen 3 0.0207 0.053 0.2508
Onchocerca volvulus 0.0702 0.2056 0.4279
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3279 1 1
Loa Loa (eye worm) animal heme peroxidase 0.0238 0.0624 0.0624
Brugia malayi Integrin alpha pat-2 precursor 0.0151 0.0356 0.035
Brugia malayi hypothetical protein 0.0047 0.0036 0.003
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0099 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1157 0.3459 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0273 0.0734 0.0728
Brugia malayi cathepsin Z-like cysteine proteinase 0.0207 0.053 0.0524
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0142 0.0483
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0207 0.053 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0032 0.0026
Plasmodium vivax proteasome subunit beta type-2, putative 0.0044 0.0026 0.0071
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0047 0.0036 0.0036
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0224 0.0581 0.0581
Echinococcus multilocularis proteasome (prosome, macropain) 0.015 0.0354 0.0348
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Echinococcus granulosus EF HAND 1 calcium binding site 0.0139 0.0319 0.0314
Schistosoma mansoni hypothetical protein 0.0139 0.0319 0.0319
Brugia malayi Calmodulin-like protein 0.0139 0.0319 0.0314
Brugia malayi Importin beta-1 subunit 0.0056 0.0065 0.0059
Loa Loa (eye worm) hypothetical protein 0.0201 0.051 0.051
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0114 0.0243 0.0237
Toxoplasma gondii cathepsin CPL 0.0702 0.2056 0.5937
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Giardia lamblia Cathepsin B precursor 0.0207 0.053 0.1485
Echinococcus multilocularis cathepsin L cysteine protease 0.0702 0.2056 0.2051
Echinococcus multilocularis cathepsin L 0.0207 0.053 0.0524
Loa Loa (eye worm) prolyl oligopeptidase 0.0081 0.0142 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Trypanosoma brucei Calpain-like protein 2 0.0273 0.0734 0.1602
Leishmania major calcineurin B subunit, putative 0.0139 0.0319 0.0907
Schistosoma mansoni cathepsin D (A01 family) 0.0316 0.0866 0.0866
Loa Loa (eye worm) animal heme peroxidase 0.0238 0.0624 0.0624
Schistosoma mansoni hypothetical protein 0.0599 0.1739 0.1739
Loa Loa (eye worm) hypothetical protein 0.0037 0.0006 0.0006
Onchocerca volvulus 0.0702 0.2056 0.4279
Giardia lamblia Proteasome subunit beta type 2 0.0044 0.0026 0.0021
Loa Loa (eye worm) animal heme peroxidase 0.0238 0.0624 0.0624
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Leishmania major centrin, putative,caltractin, putative 0.0139 0.0319 0.0907
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0207 0.053 0.2508
Trypanosoma brucei prolyl oligopeptidase, putative 0.0233 0.0609 0.1328
Loa Loa (eye worm) hypothetical protein 0.0037 0.0006 0.0006
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0067 0.0099 0.0392
Loa Loa (eye worm) hypothetical protein 0.0037 0.0006 0.0006
Brugia malayi proteasome subunit beta type 2 0.0044 0.0026 0.002
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0139 0.0319 0.0314
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0041 0.0019 0.0013
Schistosoma mansoni peroxidasin 0.0238 0.0624 0.0624
Schistosoma mansoni peroxidasin 0.0238 0.0624 0.0624
Brugia malayi Proteasome A-type and B-type family protein 0.015 0.0354 0.0348
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0207 0.053 0.1517
Brugia malayi Cathepsin L-like cysteine proteinase 0.0501 0.1437 0.1432
Echinococcus multilocularis integrin alpha ps 0.0068 0.01 0.0094
Trypanosoma brucei Aph-1 protein, putative 0.0098 0.0195 0.0415
Echinococcus granulosus cathepsin L 0.0408 0.1148 0.1143
Trichomonas vaginalis calcium binding protein, putative 0.0146 0.0341 0.0971
Giardia lamblia Proteasome subunit beta type 1 0.0067 0.0099 0.0232
Echinococcus multilocularis calmodulin 0.0139 0.0319 0.0314
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0273 0.0734 0.2109
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0607 0.1763 0.1763
Onchocerca volvulus 0.0702 0.2056 0.4279
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0168 0.0409 0.0404
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0037 0.0031
Trypanosoma brucei antigen, putative 0.0947 0.2812 0.6176
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0545 0.1571 0.1571
Echinococcus granulosus prolyl endopeptidase 0.0545 0.1571 0.1566
Loa Loa (eye worm) hypothetical protein 0.0501 0.1437 0.1437
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0392 0.1101 0.1101
Brugia malayi RNA, U transporter 1 0.016 0.0384 0.0378
Brugia malayi calcium-binding protein 0.0139 0.0319 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.053 0.1517
Leishmania major centrin, putative 0.0139 0.0319 0.0907
Schistosoma mansoni hypothetical protein 0.0139 0.0319 0.0319
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0207 0.053 0.2508
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0139 0.0319 0.0314
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0233 0.0609 0.1747
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Brugia malayi calpain 5 0.0273 0.0734 0.0728
Schistosoma mansoni calcium binding atopy-related autoantigen 0.014 0.0324 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0702 0.2056 0.5937
Schistosoma mansoni survival motor neuron protein 0.0094 0.0182 0.0182
Plasmodium vivax serine-repeat antigen (SERA) 0.0207 0.053 0.1867
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3279 1 1
Trypanosoma brucei calmodulin, putative 0.0139 0.0319 0.069
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Plasmodium falciparum serine repeat antigen 8 0.0207 0.053 0.2508
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0392 0.1101 0.2286
Trichomonas vaginalis set domain proteins, putative 0.0461 0.1313 0.3784
Brugia malayi prolyl oligopeptidase family protein 0.0081 0.0142 0.0136
Giardia lamblia Hypothetical protein 0.014 0.0324 0.0888
Plasmodium falciparum plasmepsin X 0.0276 0.0741 0.3547
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0201 0.051 0.0504
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0392 0.1101 0.1096
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Trichomonas vaginalis ran, putative 0.0041 0.0019 0.0037
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Leishmania major kinesin, putative 0.0674 0.1969 0.5686
Echinococcus multilocularis neurocalcin 0.0139 0.0319 0.0314
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.053 0.053
Plasmodium vivax aspartyl protease, putative 0.0276 0.0741 0.2621
Loa Loa (eye worm) hypothetical protein 0.0201 0.051 0.051
Plasmodium falciparum serine repeat antigen 7 0.0207 0.053 0.2508
Loa Loa (eye worm) hypothetical protein 0.3279 1 1
Echinococcus granulosus cathepsin l1 0.0501 0.1437 0.1432
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3279 1 1
Onchocerca volvulus 0.0501 0.1437 0.2988
Onchocerca volvulus 0.0207 0.053 0.1093
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0233 0.0609 0.0604
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0252 0.0669 0.0669
Loa Loa (eye worm) prolyl oligopeptidase 0.0392 0.1101 0.1101
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0044 0.0026 0.002
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.123 0.3683 0.3683
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0273 0.0734 0.0728
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0233 0.0609 1
Mycobacterium tuberculosis Probable peptidase 0.0233 0.0609 0.4587
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0139 0.0319 0.0319
Plasmodium falciparum serine repeat antigen 4 0.0207 0.053 0.2508
Toxoplasma gondii aspartyl protease ASP3 0.0276 0.0741 0.213
Plasmodium vivax vivapain-2 0.0702 0.2056 0.7306
Echinococcus granulosus calpain A 0.2679 0.8149 0.8148
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0273 0.0734 0.0728
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.053 0.0524
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2812 0.6176
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1157 0.3459 0.3459
Trypanosoma cruzi conserved protein 0.0273 0.0734 0.0728
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0168 0.0409 0.1168
Giardia lamblia Encystation-specific protease 0.0207 0.053 0.1485
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Onchocerca volvulus 0.014 0.0324 0.0665
Schistosoma mansoni mitochondrial solute carrier 0.0139 0.0319 0.0319
Giardia lamblia Cathepsin L precursor 0.0207 0.053 0.1485
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.053 0.0524
Loa Loa (eye worm) hypothetical protein 0.2539 0.7717 0.7717
Schistosoma mansoni rab 0.0139 0.0319 0.0319
Brugia malayi proteasome subunit beta type 1 0.0067 0.0099 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0408 0.1148 0.3309
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0065 0.017
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0139 0.0319 0.0907
Schistosoma mansoni integrin alpha-ps 0.0068 0.01 0.01
Trypanosoma cruzi cysteine proteinase, putative 0.0408 0.1148 0.1143
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0599 0.1739 0.1739
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0071 0.0071
Trypanosoma cruzi calmodulin, putative 0.0139 0.0319 0.0314
Loa Loa (eye worm) hypothetical protein 0.0037 0.0006 0.0006
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0067 0.0099 0.0099
Entamoeba histolytica grainin, putative 0.014 0.0324 0.15
Entamoeba histolytica calcium binding family protein 0.0139 0.0319 0.1475
Trichomonas vaginalis calmodulin, putative 0.0139 0.0319 0.0907
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0207 0.053 0.053
Echinococcus granulosus integrin beta 2 0.0229 0.0597 0.0591
Trypanosoma brucei mitochondrial calcium uptake 1 0.0139 0.0319 0.069
Echinococcus multilocularis cathepsin L cysteine protease 0.0702 0.2056 0.2051
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0273 0.0734 0.2109
Trypanosoma brucei prolyl endopeptidase 0.0545 0.1571 0.3445
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.2056 0.2051
Entamoeba histolytica cysteine protease, putative 0.0207 0.053 0.2508
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0073 0.1114
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0233 0.0609 0.4587
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0168 0.0409 0.0888
Entamoeba histolytica cysteine protease, putative 0.0207 0.053 0.2508
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0207 0.053 0.0524
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2812 0.2807
Echinococcus granulosus proteasome prosome macropain 0.015 0.0354 0.0348
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.1602
Plasmodium vivax importin-beta 2, putative 0.0056 0.0065 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Entamoeba histolytica cysteine proteinase, putative 0.0408 0.1148 0.5545
Entamoeba histolytica cysteine protease, putative 0.0207 0.053 0.2508
Brugia malayi EF hand family protein 0.0139 0.0319 0.0314
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.053 0.0524
Trypanosoma cruzi kinesin, putative 0.0674 0.1969 0.1964
Giardia lamblia Cysteine protease 0.0207 0.053 0.1485
Loa Loa (eye worm) animal heme peroxidase 0.0238 0.0624 0.0624
Giardia lamblia Hypothetical protein 0.0207 0.053 0.1485
Echinococcus granulosus cathepsin b 0.3279 1 1
Echinococcus granulosus integrin alpha ps 0.0068 0.01 0.0094
Trypanosoma brucei I/6 autoantigen 0.0139 0.0319 0.069
Brugia malayi Papain family cysteine protease containing protein 0.0408 0.1148 0.1143
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Brugia malayi Animal haem peroxidase family protein 0.0238 0.0624 0.0618
Onchocerca volvulus 0.0702 0.2056 0.4279
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.0195 0.0189
Onchocerca volvulus Dual oxidase homolog 0.0238 0.0624 0.129
Trypanosoma cruzi cruzipain precursor, putative 0.0201 0.051 0.0504
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0273 0.0734 0.2109
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Giardia lamblia Cysteine protease 0.0207 0.053 0.1485
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0044 0.0026 0.0044
Toxoplasma gondii preprocathepsin c precursor, putative 0.0207 0.053 0.1517
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0067 0.0099 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0142 0.0393
Plasmodium falciparum calpain 0.0273 0.0734 0.3511
Entamoeba histolytica calmodulin, putative 0.0139 0.0319 0.1475
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0702 0.2056 0.2056
Toxoplasma gondii EF hand domain-containing protein 0.0139 0.0319 0.0907
Echinococcus granulosus calpain 0.0947 0.2812 0.2807
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.053 0.1517
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Onchocerca volvulus Peroxidasin homolog 0.0238 0.0624 0.129
Loa Loa (eye worm) ctsf protein 0.0702 0.2056 0.2056
Schistosoma mansoni hypothetical protein 0.1511 0.4549 0.4549
Schistosoma mansoni cathepsin S (C01 family) 0.0207 0.053 0.053
Trypanosoma cruzi centrin, putative 0.0146 0.0341 0.0336
Echinococcus multilocularis cathepsin L 0.0408 0.1148 0.1143
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0058 0.0071 0.0065
Brugia malayi Cathepsin L-like precursor 0.0702 0.2056 0.2051
Echinococcus multilocularis calpain 7 (C02 family) 0.0947 0.2812 0.2807
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0073 0.0067
Trichomonas vaginalis calpain, putative 0.0273 0.0734 0.2109
Brugia malayi Cathepsin L-like precursor 0.0702 0.2056 0.2051
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0067 0.0099 0.0392
Trypanosoma cruzi cruzipain precursor, putative 0.0702 0.2056 0.2051
Loa Loa (eye worm) hypothetical protein 0.0114 0.0243 0.0243
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0139 0.0319 0.0314
Echinococcus granulosus integrin alpha 3 0.0116 0.0248 0.0242
Brugia malayi EF hand family protein 0.014 0.0324 0.0319
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0037 0.0031
Echinococcus multilocularis peroxidasin 0.0238 0.0624 0.0618
Trypanosoma brucei hypothetical protein, conserved 0.0139 0.0319 0.069
Loa Loa (eye worm) hypothetical protein 0.0207 0.053 0.053
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0207 0.053 0.2508
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2812 0.2807
Schistosoma mansoni centrin 0.0139 0.0319 0.0319
Plasmodium falciparum serine repeat antigen 9 0.0207 0.053 0.2508
Loa Loa (eye worm) hypothetical protein 0.0201 0.051 0.051
Trypanosoma brucei calpain, putative 0.0273 0.0734 0.1602
Giardia lamblia Proteasome subunit beta type 5 precursor 0.015 0.0354 0.0974
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0702 0.2056 0.5937
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Toxoplasma gondii calmodulin CAM1 0.014 0.0324 0.0922
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.2807
Toxoplasma gondii hypothetical protein 0.0273 0.0734 0.2109
Echinococcus granulosus cathepsin l cysteine peptidase 0.0702 0.2056 0.2051
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Onchocerca volvulus 0.0461 0.1313 0.2729
Leishmania major cathepsin L-like protease 0.0702 0.2056 0.5937
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0545 0.1571 0.1571
Entamoeba histolytica cysteine proteinase, putative 0.0702 0.2056 1
Echinococcus multilocularis EF hand domain containing family member A2 0.0139 0.0319 0.0314
Trypanosoma brucei centrin-3 0.0146 0.0341 0.0738
Plasmodium falciparum cysteine proteinase falcipain 1 0.0408 0.1148 0.5545
Echinococcus granulosus calpain A 0.0947 0.2812 0.2807
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0273 0.0734 0.0728
Echinococcus granulosus EF hand domain containing family member A2 0.0139 0.0319 0.0314
Trypanosoma cruzi centrin-3 0.0146 0.0341 0.0336
Giardia lamblia Cathepsin L-like protease 0.0207 0.053 0.1485
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0405 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.0702 0.2056 0.2056
Schistosoma mansoni cathepsin s 0.0201 0.051 0.051
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Entamoeba histolytica prolyl oligopeptidase family protein 0.0081 0.0142 0.0603
Trypanosoma cruzi kinesin, putative 0.0674 0.1969 0.1964
Brugia malayi prolyl oligopeptidase family protein 0.0081 0.0142 0.0136
Brugia malayi Cathepsin L-like precursor 0.0501 0.1437 0.1432
Onchocerca volvulus 0.0238 0.0624 0.129
Giardia lamblia Cathepsin B precursor 0.0207 0.053 0.1485
Schistosoma mansoni cathepsin F (C01 family) 0.0501 0.1437 0.1437
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2812 0.6176
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0207 0.053 0.1485
Schistosoma mansoni cathepsin F (C01 family) 0.0702 0.2056 0.2056
Loa Loa (eye worm) hypothetical protein 0.0118 0.0256 0.0256
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.015 0.0354 0.0348
Brugia malayi Animal haem peroxidase family protein 0.0238 0.0624 0.0618
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2677 0.8144 0.8144
Giardia lamblia Cathepsin B precursor 0.1157 0.3459 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.053 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Trypanosoma brucei proteasome beta 6 subunit 0.0067 0.0099 0.0204
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0702 0.2056 0.2051
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0139 0.0319 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.053 0.1517
Brugia malayi cathepsin Z-like cysteine proteinase 0.0207 0.053 0.0524
Trichomonas vaginalis calcineurin B subunit, putative 0.0139 0.0319 0.0907
Plasmodium falciparum proteasome subunit beta type-5 0.015 0.0354 0.1644
Trichomonas vaginalis centrin, putative 0.0139 0.0319 0.0907
Giardia lamblia Hypothetical protein 0.0207 0.053 0.1485
Entamoeba histolytica prolyl oligopeptidase family protein 0.0081 0.0142 0.0603
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0081 0.0142 0.0603
Trypanosoma brucei centrin, putative 0.0139 0.0319 0.069
Entamoeba histolytica cysteine protease, putative 0.0408 0.1148 0.5545
Trichomonas vaginalis calcium binding protein, putative 0.0139 0.0319 0.0907
Schistosoma mansoni calmodulin 0.0139 0.0319 0.0319
Plasmodium falciparum peptidase, putative 0.0081 0.0142 0.0603
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0207 0.053 0.1867
Onchocerca volvulus 0.1591 0.4796 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0702 0.2056 0.5937
Trichomonas vaginalis calpain, putative 0.0273 0.0734 0.2109
Brugia malayi cathepsin F-like cysteine proteinase 0.0207 0.053 0.0524
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0065 0.0129
Onchocerca volvulus Peroxidasin homolog 0.0238 0.0624 0.129
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0081 0.0142 0.0142
Loa Loa (eye worm) cathepsin B 0.1157 0.3459 0.3459
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.2056 0.4512
Plasmodium vivax calpain, putative 0.0947 0.2812 1
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0379 0.1059 0.1054
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.8126
Brugia malayi Cathepsin L-like precursor 0.0702 0.2056 0.2051
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Loa Loa (eye worm) hypothetical protein 0.0238 0.0624 0.0624
Trypanosoma cruzi cysteine peptidase, putative 0.0201 0.051 0.0504
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Trichomonas vaginalis calpain, putative 0.0273 0.0734 0.2109
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0545 0.1571 0.1571
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2812 0.2807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.053 0.1517
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.053 0.1485
Loa Loa (eye worm) programmed cell death protein 6 0.014 0.0324 0.0324
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0044 0.0026 0.002
Plasmodium vivax vivapain-2 0.0702 0.2056 0.7306
Leishmania major calmodulin, putative 0.0139 0.0319 0.0907
Echinococcus multilocularis gamma secretase subunit aph 1 0.0252 0.0669 0.0664
Giardia lamblia Cysteine protease 0.0207 0.053 0.1485
Echinococcus granulosus cathepsin l1 0.0702 0.2056 0.2051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0408 0.1148 0.3309
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0545 0.1571 0.4534
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2812 0.2807
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.2109
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0139 0.0319 0.0907
Entamoeba histolytica protein kinase, putative 0.0674 0.1969 0.9575
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0273 0.0734 0.0728
Plasmodium falciparum serine repeat antigen 2 0.0207 0.053 0.2508
Loa Loa (eye worm) blistered cuticle protein 3 0.0238 0.0624 0.0624
Brugia malayi Animal haem peroxidase family protein 0.0238 0.0624 0.0618
Leishmania major programmed cell death 6 protein-like protein 0.0139 0.0319 0.0907
Echinococcus multilocularis calbindin 32 0.014 0.0324 0.0319
Trichomonas vaginalis calcium binding protein, putative 0.0139 0.0319 0.0907
Trypanosoma cruzi prolyl endopeptidase 0.0545 0.1571 0.1566
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.2056 0.2051
Brugia malayi programmed cell death protein 6 0.0139 0.0319 0.0314
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0037 0.0037
Echinococcus granulosus cathepsin L cysteine proteinase 0.0702 0.2056 0.2051
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.053 0.1485
Loa Loa (eye worm) calpain family protein 1 0.2539 0.7717 0.7717
Brugia malayi calpain family protein 1 0.2539 0.7717 0.7715

Activities

Activity type Activity value Assay description Source Reference
Ki (functional) = 16 nM Inhibitory constant of the compound against stimulation of alkaline phosphatase activity in Ishikawa cells ChEMBL. 15743187
RBA (binding) = 3.7 % Relative binding affinity for estrogen receptor of rat uterine cytosol ChEMBL. 15743187

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.