Detailed information for compound 322194

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 304.27 | Formula: C16H13FO5
  • H donors: 0 H acceptors: 3 LogP: 2.42 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC1=C(OC)C(=O)C(=C(C1=O)C(=O)c1ccc(cc1)F)C
  • InChi: 1S/C16H13FO5/c1-8-11(13(19)9-4-6-10(17)7-5-9)14(20)16(22-3)15(21-2)12(8)18/h4-7H,1-3H3
  • InChiKey: OWVFYULRMRVWJG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.086 0.1324 0.1854
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.208 0.3245 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0036
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0069 0.0093
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0025 0.01
Brugia malayi beta-lactamase family protein 0.0039 0.0032 0.0045
Trichomonas vaginalis calcium binding protein, putative 0.0293 0.0433 0.1713
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0117 0.0158
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0025 0.009
Schistosoma mansoni neuronal calcium sensor 0.0293 0.0433 0.0433
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0168 0.0667
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Toxoplasma gondii EF hand domain-containing protein 0.0053 0.0054 0.0213
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0032 0.0126
Trypanosoma cruzi small myristoylated protein 1-1 0.0381 0.057 0.0798
Schistosoma mansoni chromatin regulatory protein sir2 0.0139 0.0189 0.0189
Giardia lamblia Dipeptidyl-peptidase I precursor 0.031 0.0458 0.1815
Loa Loa (eye worm) hypothetical protein 0.4558 0.7144 1
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0022 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Trypanosoma cruzi calmodulin, putative 0.0293 0.0433 0.0606
Leishmania major centrin, putative 0.0293 0.0433 0.1333
Leishmania major cathepsin L-like protease 0.1097 0.1698 0.5232
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0007 0.0028
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0025 0.5
Trichomonas vaginalis calpain, putative 0.0639 0.0977 0.3869
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.0045
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0092 0.0092
Entamoeba histolytica cysteine protease, putative 0.031 0.0458 0.2548
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.0478 0.1474
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0032 0.0865
Leishmania major calcineurin B subunit, putative 0.0293 0.0433 0.1333
Echinococcus multilocularis chromobox protein 1 0.0073 0.0086 0.0115
Loa Loa (eye worm) hypothetical protein 0.0106 0.0139 0.0194
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Echinococcus granulosus programmed cell death protein 6 0.0059 0.0064 0.0085
Giardia lamblia Cathepsin L precursor 0.031 0.0458 0.1815
Onchocerca volvulus 0.1097 0.1698 0.4099
Loa Loa (eye worm) hypothetical protein 0.0032 0.0021 0.003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.031 0.0458 0.0458
Giardia lamblia Programmed cell death protein-like protein 0.0053 0.0054 0.0213
Brugia malayi Probable myosin regulatory light chain 0.0059 0.0064 0.0089
Trypanosoma brucei centrin, putative 0.0293 0.0433 0.1333
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.031 0.0458 0.1815
Brugia malayi calcium-binding protein 0.0293 0.0433 0.0606
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0053 0.0054 0.0213
Trichomonas vaginalis calmodulin, putative 0.0293 0.0433 0.1713
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0639 0.0977 0.3869
Echinococcus granulosus thioredoxin glutathione reductase 0.0099 0.0128 0.0172
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0246 0.0358 0.1104
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0293 0.0433 0.0433
Schistosoma mansoni ef hand domain family member A2 0.0293 0.0433 0.0433
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0069 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0778 0.1195 0.1673
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0113
Mycobacterium tuberculosis Probable reductase 0.0227 0.0328 0.8917
Brugia malayi Fibulin-1 precursor 0.0029 0.0016 0.0023
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Entamoeba histolytica cysteine proteinase, putative 0.0629 0.0961 0.5341
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Schistosoma mansoni cathepsin B (C01 family) 0.031 0.0458 0.0458
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0062 0.0087
Plasmodium falciparum serine repeat antigen 3 0.031 0.0458 0.27
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0113
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1221 0.1893 0.5834
Onchocerca volvulus 0.031 0.0458 0.1097
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0022 0.0067
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0022 0.0067
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0125 0.0168 0.0226
Trypanosoma brucei kinesin, putative 0.1161 0.1799 0.5544
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0007 0.001
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4558 0.7144 1
Echinococcus granulosus EF hand domain containing family member A2 0.0299 0.0442 0.0595
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1801 0.2805 0.3927
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0011 0.0042
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Echinococcus multilocularis calpain 0.1801 0.2805 0.3771
Schistosoma mansoni myosin light chain 0.0053 0.0054 0.0054
Brugia malayi Heterochromatin protein 1 0.0073 0.0086 0.012
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0022 0.0029
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0025 0.01
Plasmodium falciparum centrin-1 0.0293 0.0433 0.2548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0778 0.1195 0.4732
Loa Loa (eye worm) hypothetical protein 0.4446 0.6967 0.9753
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Trichomonas vaginalis myosin light chain 1, putative 0.0293 0.0433 0.1713
Plasmodium falciparum cysteine proteinase falcipain 1 0.0629 0.0961 0.5659
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0125 0.0168 0.0519
Echinococcus multilocularis musashi 0.0055 0.0058 0.0078
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Brugia malayi Papain family cysteine protease containing protein 0.0629 0.0961 0.1345
Schistosoma mansoni calmodulin 0.0293 0.0433 0.0433
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0113
Loa Loa (eye worm) hypothetical protein 0.0293 0.0433 0.0606
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0016
Leishmania major cathepsin L-like protease 0.1381 0.2145 0.661
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0189 0.075
Schistosoma mansoni chromobox protein 0.0073 0.0086 0.0086
Giardia lamblia Cathepsin B precursor 0.031 0.0458 0.1815
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0008
Entamoeba histolytica cysteine protease, putative 0.031 0.0458 0.2548
Onchocerca volvulus 0.0023 0.0007 0.0005
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0168 0.0236
Giardia lamblia Cysteine protease 0.031 0.0458 0.1815
Echinococcus granulosus cysteine protease 0.0629 0.0961 0.1292
Schistosoma mansoni chromobox protein 0.0073 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0029 0.0017 0.0017
Schistosoma mansoni calmodulin related calcium binding protein 0.0293 0.0433 0.0433
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0116 0.0154 0.0476
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4446 0.6967 0.6967
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0074 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Trichomonas vaginalis centrin, putative 0.0053 0.0054 0.0213
Leishmania major kinesin, putative 0.1161 0.1799 0.5544
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0117 0.0164
Leishmania major cathepsin L-like protease 0.1097 0.1698 0.5232
Echinococcus multilocularis neurocalcin 0.0293 0.0433 0.0582
Plasmodium falciparum serine repeat antigen 7 0.031 0.0458 0.27
Brugia malayi Calmodulin-like protein 0.0293 0.0433 0.0606
Loa Loa (eye worm) programmed cell death protein 6 0.0299 0.0442 0.0619
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0025 0.009
Leishmania major META domain containing protein 0.0221 0.0318 0.0981
Onchocerca volvulus Matrix metalloproteinase homolog 0.0048 0.0047 0.0101
Trypanosoma brucei Calpain-like protein CALP1.3 0.086 0.1324 0.4081
Onchocerca volvulus 0.0039 0.0032 0.0064
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0227 0.0328 0.8917
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1175 0.182 0.561
Trypanosoma brucei cysteine peptidase C (CPC) 0.1624 0.2526 0.7784
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0055 0.0324
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0478 0.067
Trypanosoma cruzi major cysteine proteinase, putative 0.031 0.0458 0.0642
Plasmodium vivax vivapain-3 0.0629 0.0961 0.3425
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0025 0.145
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0054 0.0213
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0116 0.0154 0.0476
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0032 0.0043
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0639 0.0977 0.3869
Trypanosoma brucei centrin-3 0.0346 0.0515 0.1588
Loa Loa (eye worm) hypothetical protein 0.0319 0.0474 0.0663
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0011 0.0042
Plasmodium vivax serine-repeat antigen (SERA), putative 0.031 0.0458 0.1634
Echinococcus multilocularis cysteine protease 0.1097 0.1698 0.2282
Brugia malayi calpain D 0.0639 0.0977 0.1368
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0004 0.021
Brugia malayi Latrophilin receptor protein 2 0.0029 0.0017 0.0024
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.031 0.0458 0.0458
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0007 0.001
Trichomonas vaginalis set domain proteins, putative 0.0487 0.0737 0.2919
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Schistosoma mansoni hypothetical protein 0.0399 0.0598 0.0598
Leishmania major protein kinase, putative 0.0293 0.0433 0.1333
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0025 0.015
Loa Loa (eye worm) hypothetical protein 0.031 0.0458 0.0642
Onchocerca volvulus 0.0069 0.008 0.0182
Echinococcus granulosus calmodulin 0.0293 0.0433 0.0582
Plasmodium vivax serine-repeat antigen (SERA), putative 0.031 0.0458 0.1634
Plasmodium falciparum cysteine proteinase falcipain 3 0.1097 0.1698 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.031 0.0458 0.1815
Schistosoma mansoni hypothetical protein 0.0055 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0639 0.0977 0.3869
Echinococcus granulosus cathepsin l cysteine peptidase 0.1097 0.1698 0.2282
Leishmania major centrin, putative,caltractin, putative 0.0293 0.0433 0.1333
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0293 0.0433 0.1713
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Schistosoma mansoni hypothetical protein 0.0069 0.008 0.008
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Brugia malayi cathepsin Z-like cysteine proteinase 0.031 0.0458 0.0642
Brugia malayi Cytochrome P450 family protein 0.0032 0.0022 0.003
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0086 0.0339
Brugia malayi Cathepsin L-like precursor 0.0778 0.1195 0.1673
Leishmania major hypothetical protein, conserved 0.0293 0.0433 0.1333
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.0011
Mycobacterium tuberculosis Conserved protein 0.0039 0.0032 0.0865
Trypanosoma brucei hypothetical protein 0.0919 0.1417 0.4368
Plasmodium vivax vivapain-2 0.1097 0.1698 0.6052
Echinococcus multilocularis calcium uptake protein 1 0.0299 0.0442 0.0595
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0032 0.0534
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0004 0.021
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0032 0.0126
Echinococcus multilocularis calcyphosin protein 0.0053 0.0054 0.0072
Trypanosoma cruzi small myristoylated protein 1-2 0.0381 0.057 0.0798
Echinococcus multilocularis thyroid hormone receptor alpha 0.0146 0.02 0.0269
Loa Loa (eye worm) myosin Light Chain family member 0.0059 0.0064 0.0089
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0919 0.1417 0.4368
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0018
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0183 0.0246
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0029 0.0017 0.0023
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0411 0.1267
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0117 0.0164
Trypanosoma cruzi centrin, putative 0.0346 0.0515 0.0721
Echinococcus multilocularis calpain 5 0.1801 0.2805 0.3771
Brugia malayi Kringle domain containing protein 0.0023 0.0007 0.001
Onchocerca volvulus 0.0069 0.008 0.0182
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1175 0.182 0.561
Loa Loa (eye worm) hypothetical protein 0.0032 0.0022 0.003
Onchocerca volvulus 0.0487 0.0738 0.1774
Brugia malayi Papain family cysteine protease containing protein 0.031 0.0458 0.0642
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0029 0.0017 0.0023
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.4739 0.7429 0.9987
Mycobacterium tuberculosis Probable oxidoreductase 0.0252 0.0368 1
Trichomonas vaginalis caltractin, putative 0.0053 0.0054 0.0213
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.028 0.0411 0.0576
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0018 0.0025
Schistosoma mansoni cpg binding protein 0.0058 0.0062 0.0062
Echinococcus granulosus glycoprotein Antigen 5 0.0069 0.008 0.0108
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1013 0.1566 0.4825
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0024 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0035 0.014
Trichomonas vaginalis calcium binding protein, putative 0.0293 0.0433 0.1713
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.0045
Brugia malayi Cathepsin L-like precursor 0.0778 0.1195 0.1673
Echinococcus multilocularis calbindin 32 0.0299 0.0442 0.0595
Brugia malayi Pre-SET motif family protein 0.0428 0.0645 0.0902
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0025 0.01
Leishmania major hypothetical protein, conserved 0.0357 0.0534 0.1644
Plasmodium falciparum serine repeat antigen 5 0.031 0.0458 0.27
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.031 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0048 0.0047 0.0065
Loa Loa (eye worm) thioredoxin reductase 0.0099 0.0128 0.0179
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.0598 0.0805
Toxoplasma gondii centrin 0.0293 0.0433 0.1713
Brugia malayi glutathione reductase 0.0099 0.0128 0.0179
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Loa Loa (eye worm) hypothetical protein 0.0093 0.0117 0.0164
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0055 0.0324
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0032 0.0865
Echinococcus granulosus calpain A 0.1801 0.2805 0.3771
Onchocerca volvulus 0.0055 0.0058 0.0128
Brugia malayi programmed cell death protein 6 0.0293 0.0433 0.0606
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0024 0.0096
Brugia malayi Cathepsin L-like precursor 0.1097 0.1698 0.2376
Schistosoma mansoni neuronal calcium sensor 0.0293 0.0433 0.0433
Schistosoma mansoni hypothetical protein 0.0023 0.0007 0.0007
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Onchocerca volvulus 0.0055 0.0058 0.0128
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0022 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Entamoeba histolytica cysteine protease, putative 0.1097 0.1698 0.9437
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0069 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0036
Giardia lamblia Cathepsin B precursor 0.031 0.0458 0.1815
Loa Loa (eye worm) hypothetical protein 0.0062 0.0069 0.0097
Brugia malayi beta-lactamase 0.0039 0.0032 0.0045
Echinococcus multilocularis centrin 2 0.0293 0.0433 0.0582
Onchocerca volvulus Matrilysin homolog 0.0048 0.0047 0.0101
Echinococcus granulosus GPCR family 2 0.0029 0.0017 0.0023
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0012 0.0017
Brugia malayi cathepsin L-like cysteine proteinase 0.031 0.0458 0.0642
Loa Loa (eye worm) hypothetical protein 0.0063 0.0071 0.0099
Entamoeba histolytica hypothetical protein 0.031 0.0458 0.2548
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0117 0.0158
Plasmodium vivax calpain, putative 0.1801 0.2805 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0004 0.0005
Onchocerca volvulus 0.0074 0.0088 0.02
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.06 0.0915 0.1281
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0003 0.0004
Brugia malayi latrophilin 2 splice variant baaae 0.0063 0.0071 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0841 0.1294 0.3989
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1624 0.2526 0.7784
Entamoeba histolytica cysteine protease, putative 0.031 0.0458 0.2548
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4739 0.7429 0.7429
Trichomonas vaginalis calpain, putative 0.0639 0.0977 0.3869
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0069 0.008 0.0108
Echinococcus multilocularis neuronal calcium sensor 0.0293 0.0433 0.0582
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0113
Giardia lamblia Dipeptidyl-peptidase I precursor 0.031 0.0458 0.1815
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0025 1
Loa Loa (eye worm) hypothetical protein 0.3284 0.5139 0.7194
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0092 0.0092
Trypanosoma brucei Component of motile flagella 41 0.0293 0.0433 0.1333
Leishmania major hypothetical protein, conserved 0.0053 0.0055 0.017
Trypanosoma brucei conserved protein 0.023 0.0333 0.1027
Trichomonas vaginalis centrin, putative 0.0053 0.0054 0.0213
Trypanosoma cruzi cysteine peptidase, putative 0.0319 0.0474 0.0663
Echinococcus multilocularis programmed cell death protein 0.0346 0.0515 0.0693
Echinococcus multilocularis GPCR, family 2 0.0029 0.0017 0.0023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0629 0.0961 0.0961
Entamoeba histolytica cysteine proteinase 2 0.0629 0.0961 0.5341
Echinococcus granulosus cathepsin l1 0.0778 0.1195 0.1607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Toxoplasma gondii EF hand domain-containing protein 0.0293 0.0433 0.1713
Plasmodium vivax unspecified product 0.031 0.0458 0.1634
Plasmodium falciparum serine repeat antigen 1 0.031 0.0458 0.27
Plasmodium vivax SET domain protein, putative 0.0062 0.0069 0.0248
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0168 0.0936
Brugia malayi Trypsin family protein 0.0069 0.008 0.0113
Echinococcus multilocularis lamin 0.0055 0.0058 0.0078
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0022 0.1249
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0004 0.0015
Loa Loa (eye worm) glutathione reductase 0.0099 0.0128 0.0179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0293 0.0433 0.2405
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0047 0.0065
Brugia malayi cathepsin L precursor 0.031 0.0458 0.0642
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0032 0.0045
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1097 0.1698 0.2282
Entamoeba histolytica calpain large subunit domain III containing protein 0.1161 0.1799 1
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0293 0.0433 0.1713
Entamoeba histolytica cysteine proteinase 1, putative 0.0629 0.0961 0.5341
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0001 0.0004
Toxoplasma gondii cathepsin B 0.1624 0.2526 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0017 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.031 0.0458 0.1815
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1221 0.1893 0.5834
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1013 0.1566 0.2192
Echinococcus granulosus Tolloid protein 1 0.0089 0.0111 0.015
Brugia malayi Matrixin family protein 0.0053 0.0054 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Giardia lamblia Cathepsin L-like protease 0.031 0.0458 0.1815
Entamoeba histolytica cysteine proteinase, putative 0.0778 0.1195 0.6644
Brugia malayi Cathepsin L-like precursor 0.1097 0.1698 0.2376
Leishmania major phospholipase c-like protein 0.0293 0.0433 0.1333
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0064 0.0086
Giardia lamblia DINP protein human, muc B family 0.0021 0.0004 0.0015
Schistosoma mansoni calpain-7 (C02 family) 0.1801 0.2805 0.2805
Trypanosoma cruzi cysteine peptidase, putative 0.0629 0.0961 0.1345
Trypanosoma brucei trypanothione reductase 0.0099 0.0128 0.0393
Loa Loa (eye worm) hypothetical protein 0.0293 0.0433 0.0606
Leishmania major hypothetical protein, conserved 0.0869 0.1339 0.4127
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0117 0.0117
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0025 0.0025
Leishmania major calpain protease-like protein 0.0639 0.0977 0.3012
Loa Loa (eye worm) hypothetical protein 0.0054 0.0057 0.0079
Onchocerca volvulus 0.0293 0.0433 0.1035
Echinococcus granulosus lamin dm0 0.0055 0.0058 0.0078
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0293 0.0433 0.0582
Plasmodium falciparum serine repeat antigen 2 0.031 0.0458 0.27
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0069 0.0069
Schistosoma mansoni centrin-related 0.0293 0.0433 0.0433
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0032 0.0865
Trypanosoma brucei cysteine peptidase, putative 0.086 0.1324 0.4081
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0639 0.0977 0.3869
Onchocerca volvulus 0.1097 0.1698 0.4099
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1062 0.1643 0.2299
Echinococcus granulosus cathepsin L cysteine protease 0.0629 0.0961 0.1292
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0318 0.0446
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0293 0.0433 0.0606
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0025 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0318 0.0981
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0252 0.0368 1
Echinococcus multilocularis cathepsin L 0.0629 0.0961 0.1292
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0139 0.0189 0.075
Schistosoma mansoni cathepsin C 0.031 0.0458 0.0458
Schistosoma mansoni myosin regulatory light chain 0.0053 0.0054 0.0054
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0841 0.1294 0.1812
Brugia malayi Cathepsin L-like precursor 0.1097 0.1698 0.2376
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0004 0.01
Schistosoma mansoni thyroid hormone receptor 0.0146 0.02 0.02
Mycobacterium tuberculosis Conserved protein 0.0039 0.0032 0.0865
Loa Loa (eye worm) ctsf protein 0.1097 0.1698 0.2376
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0293 0.0433 0.0582
Brugia malayi Matrixin family protein 0.0022 0.0005 0.0008
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0007 0.001
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0055 0.0196
Leishmania major hypothetical protein, conserved 0.0039 0.0032 0.0098
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0022 0.0067
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.031 0.0458 0.0458
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4558 0.7144 0.7144
Trypanosoma brucei calpain-like protein, putative 0.208 0.3245 1
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0058 0.0081
Trypanosoma cruzi calmodulin, putative 0.0293 0.0433 0.0606
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Entamoeba histolytica grainin, putative 0.0299 0.0442 0.2459
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0025 0.145
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0478 0.067
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0994 0.1536 0.4733
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0004 0.0011
Leishmania major small myristoylated protein-3, putative 0.0322 0.0478 0.1474
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4558 0.7144 0.7144
Echinococcus multilocularis calumenin 0.0299 0.0442 0.0595
Trichomonas vaginalis calmodulin, putative 0.0346 0.0515 0.204
Loa Loa (eye worm) matrixin family protein 0.0053 0.0054 0.0076
Trypanosoma cruzi calpain cysteine peptidase, putative 0.208 0.3245 0.4543
Schistosoma mansoni calpain C (C02 family) 0.1801 0.2805 0.2805
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0125 0.0168 0.0226
Loa Loa (eye worm) RecQ helicase 0.0023 0.0007 0.001
Leishmania major DNA polymerase eta, putative 0.0034 0.0024 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1097 0.1698 0.6721
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0036
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0069 0.008 0.008
Plasmodium falciparum serine repeat antigen 9 0.031 0.0458 0.27
Plasmodium vivax hypothetical protein, conserved 0.0299 0.0442 0.1577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.031 0.0458 0.1815
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0007 0.0044
Trichomonas vaginalis centrin, putative 0.0293 0.0433 0.1713
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0003 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0005
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0053 0.0054 0.0117
Brugia malayi Trypsin-like protease protein 5 0.0069 0.008 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0022 0.003
Onchocerca volvulus 0.0069 0.008 0.0182
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4558 0.7144 0.7144
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.086 0.1324 0.1854
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0054 0.0075
Echinococcus granulosus calbindin 32 0.0299 0.0442 0.0595
Trypanosoma cruzi kinesin, putative 0.1161 0.1799 0.2518
Trichomonas vaginalis chromobox protein, putative 0.0044 0.004 0.0159
Giardia lamblia Cathepsin L precursor 0.031 0.0458 0.1815
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0032 0.0126
Toxoplasma gondii thioredoxin reductase 0.0099 0.0128 0.0505
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0221 0.0318 0.0981
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0221 0.0318 0.0981
Echinococcus multilocularis calmodulin 0.0293 0.0433 0.0582
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.028 0.0411 0.1267
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0022 0.003
Echinococcus granulosus EF hand domain containing family member A2 0.0293 0.0433 0.0582
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.0036 0.0028 0.004
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0148 0.0204 0.0286
Trichomonas vaginalis calmodulin, putative 0.0293 0.0433 0.1713
Schistosoma mansoni cathepsin F (C01 family) 0.1097 0.1698 0.1698
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0032 0.0032
Echinococcus granulosus calpain 5 0.1801 0.2805 0.3771
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.208 0.3245 0.4543
Onchocerca volvulus 0.0148 0.0204 0.0481
Loa Loa (eye worm) EF hand family protein 0.0293 0.0433 0.0606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Giardia lamblia Hypothetical protein 0.0125 0.0168 0.0667
Entamoeba histolytica cysteine protease, putative 0.031 0.0458 0.2548
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0117 0.0117
Entamoeba histolytica cysteine proteinase, putative 0.1097 0.1698 0.9437
Schistosoma mansoni hypothetical protein 0.0029 0.0017 0.0017
Echinococcus multilocularis calmodulin 0.0293 0.0433 0.0582
Leishmania major cathepsin L-like protease 0.1097 0.1698 0.5232
Trypanosoma brucei calmodulin, putative 0.0293 0.0433 0.1333
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0168 0.0236
Brugia malayi EF hand family protein 0.0299 0.0442 0.0619
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.086 0.1324 0.4081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Echinococcus granulosus dna polymerase kappa 0.0021 0.0004 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4558 0.7144 0.7144
Giardia lamblia Cathepsin L precursor 0.031 0.0458 0.1815
Loa Loa (eye worm) hypothetical protein 0.0055 0.0058 0.0081
Onchocerca volvulus 0.2645 0.4133 1
Echinococcus granulosus calpain 0.1801 0.2805 0.3771
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0058 0.0081
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0029 0.0017 0.0024
Brugia malayi CXXC zinc finger family protein 0.0058 0.0062 0.0087
Entamoeba histolytica hypothetical protein 0.0029 0.0017 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Entamoeba histolytica papain family cysteine protease domain containing protein 0.031 0.0458 0.2548
Schistosoma mansoni hypothetical protein 0.0293 0.0433 0.0433
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0022 0.0087
Schistosoma mansoni cpg binding protein 0.0061 0.0067 0.0067
Schistosoma mansoni DNA polymerase eta 0.0048 0.0047 0.0047
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0032 0.0126
Loa Loa (eye worm) hypothetical protein 0.034 0.0506 0.0708
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.208 0.3245 0.4543
Trypanosoma cruzi cruzipain precursor, putative 0.1381 0.2145 0.3003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.031 0.0458 0.0642
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Onchocerca volvulus 0.0069 0.008 0.0182
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0293 0.0433 0.0606
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0293 0.0433 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0004
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0189 0.075
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0582 0.0887 0.1242
Brugia malayi Calcitonin receptor-like protein seb-1 0.0093 0.0117 0.0164
Schistosoma mansoni hypothetical protein 0.0135 0.0183 0.0183
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0069 0.008 0.008
Loa Loa (eye worm) matrixin family protein 0.0048 0.0047 0.0066
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.0045
Onchocerca volvulus 0.1097 0.1698 0.4099
Loa Loa (eye worm) AStacin protease 0.0056 0.0059 0.0082
Entamoeba histolytica cysteine proteinase, putative 0.1097 0.1698 0.9437
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0016 0.0065
Brugia malayi Papain family cysteine protease containing protein 0.031 0.0458 0.0642
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.0045
Loa Loa (eye worm) fibroinase 0.1097 0.1698 0.2376
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0022 0.1249
Trypanosoma cruzi I/6 autoantigen, putative 0.0293 0.0433 0.0606
Plasmodium vivax serine-repeat antigen (SERA) 0.031 0.0458 0.1634
Brugia malayi Trypsin family protein 0.0069 0.008 0.0113
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0005
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0029 0.0017 0.0023
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0022 0.0022
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0227 0.0328 0.8917
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0022 0.0087
Leishmania major cathepsin L-like protease 0.1381 0.2145 0.661
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0077
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0024
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0299 0.0442 0.0442
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.0022 0.0087
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0069 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.2002 0.3122 0.4371
Plasmodium vivax glutathione reductase, putative 0.0099 0.0128 0.0455
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.031 0.0458 0.1634
Brugia malayi Cathepsin L-like precursor 0.1097 0.1698 0.2376
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0007 0.003
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0069 0.008 0.0113
Loa Loa (eye worm) transcriptional regulator 0.0125 0.0168 0.0236
Leishmania major i/6 autoantigen-like protein 0.0293 0.0433 0.1333
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0032 0.0098
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0053 0.0054 0.0075
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0086 0.0339
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0032 0.1818
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.031 0.0458 0.1815
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0025 0.0078
Schistosoma mansoni neuronal calcium sensor 0.0293 0.0433 0.0433
Schistosoma mansoni Mername-AA248 (C02 family) 0.1801 0.2805 0.2805
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0025 0.0078
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Mycobacterium leprae Probable lipase LipE 0.0039 0.0032 0.0534
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.031 0.0458 0.1634
Echinococcus multilocularis glycoprotein Antigen 5 0.0069 0.008 0.0108
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0053 0.0054 0.0117
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0029 0.0016 0.0023
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0293 0.0433 0.0606
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0004 0.0005
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0629 0.0961 0.0961
Echinococcus multilocularis geminin 0.0358 0.0535 0.0719
Schistosoma mansoni calpain (C02 family) 0.1801 0.2805 0.2805
Trichomonas vaginalis calcium binding protein, putative 0.0293 0.0433 0.1713
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0022 0.003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0025 0.0078
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0027 0.0013 0.035
Loa Loa (eye worm) calpain 0.1801 0.2805 0.3927
Onchocerca volvulus 0.1097 0.1698 0.4099
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1097 0.1698 0.2376
Trypanosoma brucei unspecified product 0.0221 0.0318 0.0981
Trypanosoma brucei antigen, putative 0.1801 0.2805 0.8644
Trypanosoma brucei I/6 autoantigen 0.0293 0.0433 0.1333
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0007 0.001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0029 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.031 0.0458 0.0642
Brugia malayi Cathepsin L-like precursor 0.0319 0.0474 0.0663
Onchocerca volvulus Cathepsin L homolog 0.1097 0.1698 0.4099
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0168 0.0667
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.2145 0.3003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1013 0.1566 0.2192
Echinococcus multilocularis cathepsin b 0.4558 0.7144 0.9604
Echinococcus granulosus cathepsin l1 0.1097 0.1698 0.2282
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0139 0.0189 0.0255
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.0007 0.0027
Plasmodium falciparum glutathione reductase 0.0099 0.0128 0.0752
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0022 0.0129
Brugia malayi chromobox protein homolog 3 0.0041 0.0035 0.0049
Leishmania major hypothetical protein, conserved 0.0221 0.0318 0.0981
Trypanosoma brucei Calpain-like protein 1.2 0.1013 0.1566 0.4825
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0318 0.0981
Echinococcus multilocularis transmembrane protease serine 3 0.0069 0.008 0.0108
Schistosoma mansoni cathepsin F (C01 family) 0.0778 0.1195 0.1195
Onchocerca volvulus 0.1097 0.1698 0.4099
Mycobacterium ulcerans hypothetical protein 0.013 0.0175 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0032 0.0045
Giardia lamblia Cathepsin B precursor 0.031 0.0458 0.1815
Schistosoma mansoni centrin 0.0293 0.0433 0.0433
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.031 0.0458 0.1634
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.0359 0.9751
Giardia lamblia Hypothetical protein 0.031 0.0458 0.1815
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0032 0.0865
Entamoeba histolytica hypothetical protein, conserved 0.0299 0.0442 0.2459
Leishmania major DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Toxoplasma gondii hypothetical protein 0.0639 0.0977 0.3869
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0069 0.008 0.0108
Toxoplasma gondii cathepsin CPL 0.1097 0.1698 0.6721
Echinococcus granulosus dna polymerase eta 0.0048 0.0047 0.0063
Mycobacterium ulcerans hydrolase 0.0027 0.0013 0.0736
Echinococcus granulosus lamin 0.0055 0.0058 0.0078
Leishmania major cathepsin L-like protease 0.1097 0.1698 0.5232
Trichomonas vaginalis calcium binding protein, putative 0.0346 0.0515 0.204
Trichomonas vaginalis kakapo, putative 0.0053 0.0054 0.0213
Trypanosoma cruzi caltractin, putative 0.0293 0.0433 0.0606
Brugia malayi cathepsin F-like cysteine proteinase 0.0319 0.0474 0.0663
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.031 0.0458 0.1815
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4739 0.7429 0.7429
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.1097 0.1698 0.2376
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0013 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0318 0.0446
Loa Loa (eye worm) sirtuin 4 0.0032 0.0022 0.0031
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0025 0.01
Echinococcus multilocularis calpain 7 (C02 family) 0.1801 0.2805 0.3771
Echinococcus granulosus chromatin regulatory protein sir2 0.0125 0.0168 0.0226
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.208 0.3245 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1221 0.1893 0.5834
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.031 0.0458 0.1634
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0086 0.0106 0.0148
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0032 0.0865
Brugia malayi Matrixin family protein 0.0022 0.0005 0.0008
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0411 0.1267
Mycobacterium tuberculosis Probable dehydrogenase 0.0227 0.0328 0.8917
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Trichomonas vaginalis calmodulin, putative 0.0293 0.0433 0.1713
Loa Loa (eye worm) hypothetical protein 0.0319 0.0474 0.0663
Trichomonas vaginalis calmodulin, putative 0.0299 0.0442 0.1751
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0025 0.069
Trichomonas vaginalis centrin, putative 0.0053 0.0054 0.0213
Loa Loa (eye worm) hypothetical protein 0.0053 0.0054 0.0075
Schistosoma mansoni hypothetical protein 0.0031 0.002 0.002
Loa Loa (eye worm) cysteine protease 0.1097 0.1698 0.2376
Trichomonas vaginalis calmodulin, putative 0.0293 0.0433 0.1713
Brugia malayi cahepsin L-like non-peptiedase homolog 0.031 0.0458 0.0642
Schistosoma mansoni cathepsin F (C01 family) 0.1097 0.1698 0.1698
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0025 0.145
Trypanosoma brucei mitochondrial calcium uptake 1 0.0293 0.0433 0.1333
Giardia lamblia Cysteine protease 0.031 0.0458 0.1815
Trypanosoma brucei small myristoylated protein 1-1 0.0381 0.057 0.1757
Brugia malayi EF hand family protein 0.0293 0.0433 0.0606
Plasmodium falciparum thioredoxin reductase 0.0099 0.0128 0.0752
Giardia lamblia Cathepsin B precursor 0.1624 0.2526 1
Mycobacterium tuberculosis Conserved protein 0.0039 0.0032 0.0865
Leishmania major programmed cell death 6 protein-like protein 0.0293 0.0433 0.1333
Trichomonas vaginalis calcium binding proteins, putative 0.0293 0.0433 0.1713
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0032 0.0865
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0026 0.0036
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.2145 0.3003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0058 0.0081
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0022 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.031 0.0458 0.1815
Trypanosoma cruzi calpain cysteine peptidase, putative 0.086 0.1324 0.1854
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0113
Loa Loa (eye worm) calmodulin-like protein 0.0293 0.0433 0.0606
Trypanosoma cruzi unspecified product 0.0381 0.057 0.0798
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0318 0.0981
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0293 0.0433 0.0606
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0079 0.0096 0.0129
Echinococcus granulosus Mastin 0.0069 0.008 0.0108
Trypanosoma brucei centrin, putative 0.0293 0.0433 0.1333
Brugia malayi Cathepsin L-like cysteine proteinase 0.0778 0.1195 0.1673
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0022 0.003
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0168 0.0168
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0252 0.0368 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0069 0.0093
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0032 0.0126
Echinococcus multilocularis programmed cell death protein 6 0.0059 0.0064 0.0085
Echinococcus granulosus dnaJ subfamily B 0.0399 0.0598 0.0805
Leishmania major cathepsin L-like protease 0.1097 0.1698 0.5232
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0319 0.0474 0.0663
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0293 0.0433 0.1333
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0011 0.0042
Leishmania major calpain family cysteine protease-like protein 0.086 0.1324 0.4081
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0293 0.0433 0.1713
Trichomonas vaginalis calmodulin-2, putative 0.0293 0.0433 0.1713
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0189 0.075
Echinococcus multilocularis cathepsin L cysteine protease 0.1097 0.1698 0.2282
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0639 0.0977 0.3869
Leishmania major cathepsin L-like protease 0.1381 0.2145 0.661
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0005
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0293 0.0433 0.2405
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0089 0.0111 0.0111
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0639 0.0977 0.3869
Leishmania major hypothetical protein, conserved 0.0221 0.0318 0.0981
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0252 0.0368 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0007 0.0028
Plasmodium falciparum serine repeat antigen 4 0.031 0.0458 0.27
Echinococcus granulosus chromobox protein 1 0.0073 0.0086 0.0115
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0221 0.0318 0.0981
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0069 0.008 0.008
Echinococcus granulosus bloom syndrome protein 0.0023 0.0007 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0246 0.0358 0.0502
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.0022 0.003
Brugia malayi Cytochrome P450 family protein 0.0032 0.0022 0.003
Brugia malayi hypothetical protein 0.013 0.0176 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0629 0.0961 0.3804
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.086 0.1324 0.1854
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.0318 0.0446
Trypanosoma brucei calpain-like protein, putative 0.1801 0.2805 0.8644
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0221 0.0318 0.0446
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0318 0.0446
Trichomonas vaginalis calmodulin, putative 0.0053 0.0054 0.0213
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Echinococcus granulosus calpain 7 C02 family 0.1801 0.2805 0.3771
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0055 0.017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0639 0.0977 0.1368
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.2002 0.3122 0.4371
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0022 0.0087
Schistosoma mansoni reticulocalbin 0.0293 0.0433 0.0433
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.0645 0.0902
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.031 0.0458 0.1815
Trichomonas vaginalis conserved hypothetical protein 0.0293 0.0433 0.1713
Entamoeba histolytica cysteine proteinase, putative 0.0629 0.0961 0.5341
Entamoeba histolytica grainin 2 0.0346 0.0515 0.2865
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0047 0.0144
Echinococcus granulosus EF HAND 1 calcium binding site 0.0293 0.0433 0.0582
Onchocerca volvulus 0.0069 0.008 0.0182
Toxoplasma gondii centrin family protein 0.0053 0.0054 0.0213
Mycobacterium ulcerans beta-lactamase 0.0039 0.0032 0.1818
Echinococcus multilocularis calpain family protein 1, d 0.3284 0.5139 0.6909
Toxoplasma gondii EFHC1, putative 0.0293 0.0433 0.1713
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.031 0.0458 0.1815
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1801 0.2805 0.3927
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0293 0.0433 0.1333
Leishmania major calmodulin, putative 0.0293 0.0433 0.1333
Trypanosoma cruzi cysteine peptidase, putative 0.1097 0.1698 0.2376
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0168 0.0168
Schistosoma mansoni rab 0.0293 0.0433 0.0433
Echinococcus multilocularis chromatin regulatory protein sir2 0.0125 0.0168 0.0226
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.086 0.1324 0.1854
Schistosoma mansoni myosin regulatory light chain 0.0053 0.0054 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0011 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0629 0.0961 0.2961
Echinococcus multilocularis calpain A 0.4745 0.7438 1
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.0355 0.0497
Brugia malayi calpain 7 0.1801 0.2805 0.3927
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0778 0.1195 0.4732
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0227 0.0328 0.8878
Trypanosoma brucei calmodulin, putative 0.0299 0.0442 0.1363
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.031 0.0458 0.1815
Leishmania major calmodulin-like protein 0.0293 0.0433 0.1333
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1221 0.1893 0.265
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0032 0.0032
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0069 0.008 0.0108
Leishmania major sir2-family protein-like protein 0.0032 0.0022 0.0067
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0018 0.0025
Schistosoma mansoni hypothetical protein 0.0358 0.0535 0.0535
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0022 0.0031
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.031 0.0458 0.27
Leishmania major trypanothione reductase 0.0099 0.0128 0.0393
Leishmania major hypothetical protein, conserved 0.0023 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0113
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.0011
Echinococcus granulosus cathepsin b 0.4558 0.7144 0.9604
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0004 0.0015
Echinococcus granulosus calumenin 0.0299 0.0442 0.0595
Onchocerca volvulus Cathepsin F homolog 0.1097 0.1698 0.4099
Onchocerca volvulus 0.0069 0.008 0.0182
Schistosoma mansoni calmodulin 0.0293 0.0433 0.0433
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0025 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Entamoeba histolytica hypothetical protein 0.0029 0.0017 0.0096
Echinococcus multilocularis Mastin 0.0069 0.008 0.0108
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0032 0.1818
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0055 0.0077
Brugia malayi NAD-dependent deacetylase SIRT1 0.0139 0.0189 0.0265
Echinococcus granulosus neurocalcin 0.0293 0.0433 0.0582
Echinococcus multilocularis thioredoxin glutathione reductase 0.0099 0.0128 0.0172
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0022 0.003
Brugia malayi Pre-SET motif family protein 0.0062 0.0069 0.0097
Schistosoma mansoni calpain-7 (C02 family) 0.1801 0.2805 0.2805
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0089 0.0111 0.0156
Loa Loa (eye worm) latrophilin receptor protein 2 0.0029 0.0017 0.0024
Trypanosoma brucei small myristoylated protein 1-2 0.0381 0.057 0.1757
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0979 0.1512 0.2116
Entamoeba histolytica calmodulin, putative 0.0293 0.0433 0.2405
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0069 0.0069
Trichomonas vaginalis calcium binding protein, putative 0.0053 0.0054 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1624 0.2526 1
Onchocerca volvulus 0.0039 0.0032 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.031 0.0458 0.1815
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0639 0.0977 0.3012
Entamoeba histolytica cysteine protease, putative 0.031 0.0458 0.2548
Leishmania major hypothetical protein, conserved 0.0221 0.0318 0.0981
Echinococcus multilocularis cathepsin L 0.031 0.0458 0.0616
Leishmania major centrin, putative 0.0293 0.0433 0.1333
Brugia malayi Trypsin family protein 0.0069 0.008 0.0113
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.031 0.0458 0.1634
Echinococcus multilocularis Myosin regulatory light chain 0.0053 0.0054 0.0072
Echinococcus multilocularis Calcium binding protein 0.0053 0.0054 0.0072
Plasmodium vivax serine-repeat antigen (SERA) 0.031 0.0458 0.1634
Entamoeba histolytica cysteine protease, putative 0.031 0.0458 0.2548
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0012 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0639 0.0977 0.3012
Brugia malayi hypothetical protein 0.0053 0.0055 0.0077
Onchocerca volvulus 0.0031 0.002 0.0035
Onchocerca volvulus 0.0299 0.0442 0.1058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0011 0.0042
Schistosoma mansoni cpg binding protein 0.0061 0.0067 0.0067
Loa Loa (eye worm) histone methyltransferase 0.002 0.0003 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1097 0.1698 1
Loa Loa (eye worm) calpain 5 0.1161 0.1799 0.2518
Leishmania major hypothetical protein, conserved 0.0221 0.0318 0.0981
Echinococcus multilocularis cysteine protease 0.1097 0.1698 0.2282
Loa Loa (eye worm) hypothetical protein 0.031 0.0458 0.0642
Echinococcus multilocularis chromobox protein 1 0.0073 0.0086 0.0115
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0004 0.01
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.086 0.1324 0.4081
Echinococcus multilocularis cathepsin b 0.4558 0.7144 0.9604
Onchocerca volvulus 0.1097 0.1698 0.4099
Echinococcus granulosus transmembrane protease serine 3 0.0069 0.008 0.0108
Brugia malayi hypothetical protein 0.0034 0.0025 0.0035
Brugia malayi hypothetical protein 0.0148 0.0204 0.0286
Echinococcus granulosus calcyphosin protein 0.0053 0.0054 0.0072
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0227 0.0328 0.8917
Schistosoma mansoni calmodulin-related 0.0053 0.0054 0.0054
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0007 0.001
Loa Loa (eye worm) calpain family protein 1 0.3284 0.5139 0.7194
Trypanosoma brucei calpain, putative 0.0919 0.1417 0.4368
Echinococcus granulosus programmed cell death protein 0.0346 0.0515 0.0693
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0022 0.0087
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0319 0.0474 0.0663
Giardia lamblia Cathepsin L-like protease 0.031 0.0458 0.1815
Giardia lamblia Hypothetical protein 0.0299 0.0442 0.1751
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.2145 0.3003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.031 0.0458 0.0458
Toxoplasma gondii preprocathepsin c precursor, putative 0.031 0.0458 0.1815
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0534 0.2112
Schistosoma mansoni thyroid hormone receptor 0.0146 0.02 0.02
Trypanosoma cruzi trypanothione reductase, putative 0.0099 0.0128 0.0179
Leishmania major receptor-type adenylate cyclase a-like protein 0.0221 0.0318 0.0981
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0026 0.0036
Plasmodium vivax centrin-1, putative 0.0293 0.0433 0.1542
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0032 0.0113
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1097 0.1698 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.2002 0.3122 0.9622
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1624 0.2526 0.3536
Echinococcus granulosus calcium uptake protein 1 0.0299 0.0442 0.0595
Plasmodium falciparum serine repeat antigen 8 0.031 0.0458 0.27
Echinococcus granulosus cathepsin L 0.0629 0.0961 0.1292
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0036
Toxoplasma gondii centrin, putative 0.0293 0.0433 0.1713
Trypanosoma brucei hypothetical protein, conserved 0.0357 0.0534 0.1644
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0299 0.0442 0.0619
Giardia lamblia Cathepsin L precursor 0.031 0.0458 0.1815
Entamoeba histolytica calmodulin, putative 0.0053 0.0054 0.03
Leishmania major mitochondrial DNA polymerase beta 0.0246 0.0358 0.1104
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0047 0.0065
Brugia malayi Cathepsin L-like precursor 0.1097 0.1698 0.2376
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.086 0.1324 0.4081
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0053 0.0054 0.0192
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0011 0.0042
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.031 0.0458 0.0642
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.031 0.0458 0.0458
Plasmodium vivax vivapain-2 0.1097 0.1698 0.6052
Entamoeba histolytica papain family cysteine protease domain containing protein 0.031 0.0458 0.2548
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.0534 0.0747
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0023
Echinococcus granulosus chromobox protein 1 0.0073 0.0086 0.0115
Trypanosoma brucei Calpain-like protein 2 0.0994 0.1536 0.4733
Brugia malayi Thioredoxin reductase 0.0099 0.0128 0.0179
Toxoplasma gondii cathepsin CPC1 0.031 0.0458 0.1815
Trypanosoma brucei calpain-like protein, putative 0.1801 0.2805 0.8644
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0026 0.0036
Trypanosoma cruzi calmodulin, putative 0.0293 0.0433 0.0606
Schistosoma mansoni hypothetical protein 0.0063 0.0071 0.0071
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1801 0.2805 0.8644
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0022 0.0022
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0035 0.0072
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0841 0.1294 0.3989
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Echinococcus multilocularis cathepsin L cysteine protease 0.1097 0.1698 0.2282
Schistosoma mansoni lamin 0.0055 0.0058 0.0058
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.031 0.0458 0.1634
Brugia malayi cathepsin L-like precursor 0.0778 0.1195 0.1673
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Echinococcus granulosus intermediate filament protein 0.0055 0.0058 0.0078
Giardia lamblia Calmodulin 0.0053 0.0054 0.0213
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.0318 0.0446
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0629 0.0961 0.1345
Brugia malayi Matrixin family protein 0.0022 0.0005 0.0008
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0022 0.0031
Brugia malayi MH2 domain containing protein 0.0244 0.0355 0.0497
Onchocerca volvulus 0.1097 0.1698 0.4099
Trichomonas vaginalis calmodulin, putative 0.0293 0.0433 0.1713
Toxoplasma gondii hypothetical protein 0.004 0.0034 0.0133
Trypanosoma cruzi centrin, putative 0.0346 0.0515 0.0721
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1801 0.2805 0.3927
Loa Loa (eye worm) hypothetical protein 0.3806 0.5961 0.8345
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0221 0.0318 0.0981
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0055 0.0218
Onchocerca volvulus 0.0032 0.0021 0.0039
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Loa Loa (eye worm) hypothetical protein 0.0778 0.1195 0.1673
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0629 0.0961 0.2961
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0011 0.0042
Echinococcus multilocularis laminin 0.0029 0.0016 0.0022
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0011 0.0015
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0774 0.1189 0.1664
Loa Loa (eye worm) hypothetical protein 0.031 0.0458 0.0642
Schistosoma mansoni hypothetical protein 0.0358 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0113
Echinococcus multilocularis enteropeptidase 0.0069 0.008 0.0108
Treponema pallidum NADH oxidase 0.0034 0.0025 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0069 0.008 0.008
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0022 0.0122
Entamoeba histolytica calmodulin, putative 0.0293 0.0433 0.2405
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Toxoplasma gondii calcium binding protein precursor, putative 0.0053 0.0054 0.0213
Giardia lamblia Cysteine protease 0.031 0.0458 0.1815
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0032 0.0865
Brugia malayi calpain family protein 1 0.4446 0.6967 0.9753
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Entamoeba histolytica hypothetical protein 0.0029 0.0017 0.0096
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0117 0.0158
Brugia malayi Hemopexin family protein 0.0031 0.002 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0022 0.0078
Brugia malayi intermediate filament protein 0.0055 0.0058 0.0081
Brugia malayi beta-lactamase family protein 0.0039 0.0032 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Brugia malayi Cytochrome P450 family protein 0.0033 0.0023 0.0032
Trypanosoma cruzi major cysteine proteinase, putative 0.0594 0.0906 0.1268
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0022 0.0122
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0025 0.0036
Toxoplasma gondii calmodulin CAM1 0.0299 0.0442 0.1751
Loa Loa (eye worm) hypothetical protein 0.0041 0.0035 0.0049
Entamoeba histolytica calcium binding family protein 0.0293 0.0433 0.2405
Brugia malayi Protein kinase domain containing protein 0.0023 0.0007 0.001
Trypanosoma cruzi I/6 autoantigen, putative 0.0293 0.0433 0.0606
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0004 0.002
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.0355 0.0497
Schistosoma mansoni lamin 0.0055 0.0058 0.0058
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0055 0.0077
Brugia malayi hypothetical protein 0.0069 0.008 0.0113
Giardia lamblia Cathepsin B precursor 0.031 0.0458 0.1815
Trichomonas vaginalis calmodulin, putative 0.0293 0.0433 0.1713
Onchocerca volvulus 0.0039 0.0032 0.0064
Toxoplasma gondii calmodulin, putative 0.0053 0.0054 0.0213
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0478 0.067
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0319 0.0474 0.0663
Mycobacterium ulcerans hypothetical protein 0.0069 0.008 0.4592
Schistosoma mansoni hypothetical protein 0.0029 0.0017 0.0017
Loa Loa (eye worm) cathepsin B 0.1624 0.2526 0.3536
Toxoplasma gondii troponin c, isotype gamma, putative 0.0293 0.0433 0.1713
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0009 0.0012
Entamoeba histolytica grainin 2 0.0053 0.0054 0.03
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1097 0.1698 0.2282
Echinococcus granulosus cathepsin L cysteine proteinase 0.1097 0.1698 0.2282
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0189 0.075
Echinococcus granulosus calpain A 0.4745 0.7438 1
Leishmania major calmodulin, putative 0.0293 0.0433 0.1333
Giardia lamblia Sirtuin type 2 0.0032 0.0022 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0093 0.0117 0.0164
Trichomonas vaginalis calpain, putative 0.0639 0.0977 0.3869
Schistosoma mansoni hypothetical protein 0.0024 0.0009 0.0009
Giardia lamblia Cathepsin L precursor 0.031 0.0458 0.1815
Brugia malayi RasGEF domain containing protein 0.0053 0.0054 0.0075
Loa Loa (eye worm) hypothetical protein 0.0778 0.1195 0.1673
Mycobacterium tuberculosis Conserved hypothetical protein 0.013 0.0175 0.4759
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0025 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.031 0.0458 0.1815
Echinococcus multilocularis EF hand domain containing family member A2 0.0293 0.0433 0.0582
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.0534 0.0747
Plasmodium falciparum centrin-4 0.0053 0.0054 0.0317
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0022 0.0067
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0032 0.0045
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0095 0.0128
Plasmodium falciparum glutathione reductase 0.0034 0.0025 0.015
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.086 0.1324 0.1854
Brugia malayi fibroinase precursor 0.031 0.0458 0.0642
Trypanosoma brucei calpain, putative 0.0639 0.0977 0.3012
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0293 0.0433 0.0606
Plasmodium vivax vivapain-1 0.0629 0.0961 0.3425
Trypanosoma cruzi conserved protein 0.0869 0.1339 0.1875
Trichomonas vaginalis conserved hypothetical protein 0.031 0.0458 0.1815
Trypanosoma cruzi centrin-3 0.0346 0.0515 0.0721
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0639 0.0977 0.3869
Trypanosoma cruzi cruzipain precursor, putative 0.0319 0.0474 0.0663
Loa Loa (eye worm) hypothetical protein 0.0053 0.0054 0.0075
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0022 0.1242
Trypanosoma cruzi cysteine protease, putative 0.0629 0.0961 0.1345
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0011 0.0015
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.4739 0.7429 0.9987
Trypanosoma brucei hypothetical protein, conserved 0.0293 0.0433 0.1333
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0293 0.0433 0.1542
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.031 0.0458 0.0458
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.031 0.0458 0.0458
Trypanosoma brucei protein I/6 0.0293 0.0433 0.1333
Brugia malayi Papain family cysteine protease containing protein 0.0629 0.0961 0.1345
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.031 0.0458 0.1815
Onchocerca volvulus 0.0778 0.1195 0.2882
Loa Loa (eye worm) calpain family protein 1 0.4446 0.6967 0.9753
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.028 0.0411 0.1267
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1221 0.1893 0.265
Schistosoma mansoni hypothetical protein 0.0029 0.0017 0.0017
Brugia malayi transcriptional regulator, Sir2 family protein 0.0125 0.0168 0.0236
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0168 0.0936
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0016 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Onchocerca volvulus 0.0053 0.0054 0.0117
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0022 0.0031
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0003 0.0016
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0022 0.0594
Leishmania major hypothetical protein, conserved 0.0221 0.0318 0.0981
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.004 0.0084
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0246 0.0358 0.0502
Leishmania major calmodulin-like protein 0.0293 0.0433 0.1333
Leishmania major DNA polymerase eta, putative 0.0048 0.0047 0.0144
Onchocerca volvulus 0.0058 0.0062 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.031 0.0458 0.1815
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0017
Trypanosoma brucei calpain-like protein, putative 0.1801 0.2805 0.8644
Schistosoma mansoni cathepsin S (C01 family) 0.031 0.0458 0.0458
Loa Loa (eye worm) beta-lactamase 0.0039 0.0032 0.0045
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0025 0.0034
Mycobacterium ulcerans hypothetical protein 0.0039 0.0032 0.1818
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Toxoplasma gondii cathepsin CPC2 0.031 0.0458 0.1815
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0022 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0036
Echinococcus granulosus Calcium binding protein 0.0053 0.0054 0.0072
Trichomonas vaginalis caltractin, putative 0.0053 0.0054 0.0213
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0294 0.0434 0.0584
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0227 0.0328 0.8917
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.208 0.3245 0.4543
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0841 0.1294 0.1812
Schistosoma mansoni hypothetical protein 0.0029 0.0017 0.0017
Brugia malayi calpain 5 0.0639 0.0977 0.1368
Trichomonas vaginalis hypothetical protein 0.0639 0.0977 0.3869
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0025 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0069 0.008 0.0108
Brugia malayi cathepsin B-like cysteine proteinase 0.4558 0.7144 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0013 0.0018
Leishmania major silent information regulator 2, putative 0.0125 0.0168 0.0519
Trypanosoma brucei unspecified product 0.0021 0.0004 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.0029 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0008
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0027 0.0013 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0979 0.1512 0.2116
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0078
Giardia lamblia Cathepsin B precursor 0.1624 0.2526 1
Trypanosoma cruzi cysteine proteinase, putative 0.0629 0.0961 0.1345
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0812 0.1248 0.1678
Schistosoma mansoni mitochondrial solute carrier 0.0293 0.0433 0.0433
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.031 0.0458 0.27
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0035 0.014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.086 0.1324 0.1854
Echinococcus granulosus centrin 2 0.0293 0.0433 0.0582
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.031 0.0458 0.1815
Echinococcus multilocularis EF hand domain containing family member A2 0.0299 0.0442 0.0595
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0009 0.0012
Echinococcus granulosus cpg binding protein 0.0061 0.0067 0.0091
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0117 0.0158
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0022 0.0129
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.031 0.0458 0.27
Toxoplasma gondii calcium-dependent protein kinase 0.0299 0.0442 0.1751
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0629 0.0961 0.3804
Echinococcus multilocularis Tolloid protein 1 0.0089 0.0111 0.015
Giardia lamblia Hypothetical protein 0.031 0.0458 0.1815
Brugia malayi Cathepsin L-like precursor 0.1097 0.1698 0.2376
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0025 0.0078
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.031 0.0458 0.1634
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0016
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0029 0.0017 0.0023
Trypanosoma cruzi cysteine proteinase, putative 0.0629 0.0961 0.1345
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0139 0.0189 0.0255
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0147 0.0583
Plasmodium vivax unspecified product 0.0629 0.0961 0.3425
Brugia malayi calpain 5 0.1161 0.1799 0.2518
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0004 0.0004
Giardia lamblia Cysteine protease 0.031 0.0458 0.1815
Trichomonas vaginalis esterase, putative 0.0039 0.0032 0.0126
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1221 0.1893 0.5834
Brugia malayi Papain family cysteine protease containing protein 0.031 0.0458 0.0642
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.031 0.0458 0.0458
Brugia malayi Myosin regulatory light chain 1 0.0053 0.0054 0.0075
Trichomonas vaginalis chromobox protein, putative 0.0044 0.004 0.0159
Toxoplasma gondii calmodulin CAM2 0.0053 0.0054 0.0213
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0919 0.1417 0.4368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.031 0.0458 0.1815
Loa Loa (eye worm) papain family cysteine protease containing protein 0.031 0.0458 0.0642
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Leishmania major cytochrome p450-like protein 0.0032 0.0022 0.0067
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0025 0.01
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0095 0.0128
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0979 0.1512 0.4659
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0022 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.031 0.0458 0.1815
Schistosoma mansoni reticulocalbin 0.0299 0.0442 0.0442
Echinococcus granulosus neuronal calcium sensor 0.0293 0.0433 0.0582
Echinococcus granulosus cathepsin b 0.4558 0.7144 0.9604
Entamoeba histolytica hypothetical protein 0.0029 0.0017 0.0096
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0116 0.0154 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0318 0.0446
Schistosoma mansoni calpain-2 (C02 family) 0.0639 0.0977 0.0977
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0086 0.012
Loa Loa (eye worm) hypothetical protein 0.2645 0.4133 0.5786
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0168 0.0168
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0038 0.0053
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0025 0.0078
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0099 0.0128 0.3469
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0022 0.0031
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0022 0.0029
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.208 0.3245 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0023 0.0032
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0079 0.0096 0.0129
Brugia malayi Papain family cysteine protease containing protein 0.1097 0.1698 0.2376
Echinococcus granulosus geminin 0.0358 0.0535 0.0719
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1097 0.1698 0.6721
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0022 0.0122
Echinococcus granulosus laminin 0.0029 0.0016 0.0022
Trichomonas vaginalis calcineurin B subunit, putative 0.0299 0.0442 0.1751
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.031 0.0458 0.1634
Entamoeba histolytica cysteine proteinase, putative 0.0629 0.0961 0.5341
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0032 0.0043
Leishmania major small myristoylated protein-1 0.0381 0.057 0.1757
Onchocerca volvulus 0.0053 0.0054 0.0117
Loa Loa (eye worm) calpain D 0.0639 0.0977 0.1368
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1221 0.1893 0.265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.2145 0.661
Echinococcus multilocularis lamin dm0 0.0055 0.0058 0.0078
Loa Loa (eye worm) hypothetical protein 0.031 0.0458 0.0642
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0139 0.0189 0.0265
Giardia lamblia Encystation-specific protease 0.031 0.0458 0.1815
Echinococcus multilocularis fibrillin 1 0.0029 0.0016 0.0022
Schistosoma mansoni intermediate filament proteins 0.0055 0.0058 0.0058
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0029 0.0017 0.0023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0629 0.0961 0.0961
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.0478 0.1474
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1097 0.1698 0.6721
Entamoeba histolytica calpain family cysteine protease, putative 0.0639 0.0977 0.5432
Brugia malayi Matrixin family protein 0.0022 0.0005 0.0008
Brugia malayi calpain family protein 1 0.4446 0.6967 0.9753
Loa Loa (eye worm) hypothetical protein 0.031 0.0458 0.0642
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0069 0.0275
Trichomonas vaginalis calcineurin B subunit, putative 0.0293 0.0433 0.1713
Plasmodium falciparum serine repeat antigen 6 0.031 0.0458 0.27
Plasmodium vivax unspecified product 0.0319 0.0474 0.1688
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0025 0.015
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0016 0.0023
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1097 0.1698 0.2376
Echinococcus granulosus Myosin regulatory light chain 0.0053 0.0054 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0017 0.0066
Entamoeba histolytica cysteine proteinase, putative 0.0629 0.0961 0.5341
Brugia malayi Neuronal calcium sensor family protein 1 0.0053 0.0054 0.0075
Trichomonas vaginalis calmodulin, putative 0.0293 0.0433 0.1713
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0022 0.0087
Echinococcus granulosus cathepsin L 0.031 0.0458 0.0616
Onchocerca volvulus Cathepsin L homolog 0.031 0.0458 0.1097
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0411 0.1267
Echinococcus granulosus enteropeptidase 0.0069 0.008 0.0108
Trypanosoma cruzi kinesin, putative 0.1161 0.1799 0.2518
Giardia lamblia Cathepsin L precursor 0.031 0.0458 0.1815
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0035 0.0026 0.0079
Onchocerca volvulus Arrow homolog 0.0026 0.0012 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Toxoplasma gondii ABC1 family protein 0.0039 0.0032 0.0126
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0025 0.0036
Giardia lamblia Cathepsin B precursor 0.1624 0.2526 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0018
Echinococcus granulosus tachykinin peptides receptor 99D 0.0294 0.0434 0.0584
Trypanosoma brucei Calpain-like protein 1.1 0.1221 0.1893 0.5834
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0022 0.0031
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0293 0.0433 0.0433
Mycobacterium ulcerans lipase LipD 0.0039 0.0032 0.1818
Schistosoma mansoni cathepsin s 0.0319 0.0474 0.0474
Leishmania major hypothetical protein, conserved 0.0299 0.0442 0.1363
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.031 0.0458 0.1815
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0841 0.1294 0.3989
Brugia malayi cathepsin F-like cysteine proteinase 0.031 0.0458 0.0642
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.031 0.0458 0.1815
Brugia malayi cathepsin Z-like cysteine proteinase 0.031 0.0458 0.0642
Leishmania major small myristoylated protein-2 0.0693 0.1062 0.3274
Leishmania major hypothetical protein, unknown function 0.0639 0.0977 0.3012
Brugia malayi Trypsin family protein 0.0069 0.008 0.0113
Giardia lamblia Dipeptidyl-peptidase I precursor 0.031 0.0458 0.1815
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0022 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1097 0.1698 0.6721
Schistosoma mansoni hypothetical protein 0.0069 0.008 0.008
Plasmodium falciparum thioredoxin reductase 0.0034 0.0025 0.015
Entamoeba histolytica protein kinase, putative 0.1161 0.1799 1
Entamoeba histolytica cysteine protease, putative 0.0629 0.0961 0.5341
Plasmodium vivax thioredoxin reductase, putative 0.0099 0.0128 0.0455
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0093 0.0117 0.0164
Leishmania major hypothetical protein, conserved 0.0221 0.0318 0.0981
Echinococcus multilocularis cpg binding protein 0.0061 0.0067 0.0091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1801 0.2805 0.3927
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1112 0.1721 0.5305
Schistosoma mansoni hypothetical protein 0.0639 0.0977 0.0977
Loa Loa (eye worm) trypsin family protein 0.0069 0.008 0.0113
Entamoeba histolytica calcium-binding protein, putative 0.0293 0.0433 0.2405
Schistosoma mansoni cercarial elastase (S01 family) 0.0069 0.008 0.008
Leishmania major small myristoylated protein 4, putative 0.06 0.0915 0.282
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1175 0.182 0.561
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1624 0.2526 0.2526
Echinococcus multilocularis dna polymerase eta 0.0048 0.0047 0.0063
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.1159 0.1795 0.1795
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.086 0.1324 0.1854
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0004 0.0005
Echinococcus multilocularis programmed cell death protein 0.0346 0.0515 0.0693
Schistosoma mansoni egf-like domain protein 0.0026 0.0012 0.0012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0011 0.0042
Schistosoma mansoni neuronal calcium sensor 0.0293 0.0433 0.0433
Loa Loa (eye worm) myosin regulatory light chain 1 0.0053 0.0054 0.0075
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0025 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.0045
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0183 0.0246
Trypanosoma brucei caltractin, putative 0.0346 0.0515 0.1588
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.0045
Plasmodium falciparum calpain 0.0639 0.0977 0.5756
Echinococcus multilocularis hypothetical protein 0.1801 0.2805 0.3771
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1112 0.1721 0.5305
Giardia lamblia Cathepsin B precursor 0.031 0.0458 0.1815
Brugia malayi hypothetical protein 0.0029 0.0017 0.0024
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0639 0.0977 0.3869
Onchocerca volvulus 0.0293 0.0433 0.1035
Leishmania major cysteine peptidase A (CPA) 0.1097 0.1698 0.5232
Onchocerca volvulus Cathepsin L homolog 0.1097 0.1698 0.4099
Trichomonas vaginalis centrin, putative 0.0293 0.0433 0.1713

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 8.36000000000001 uM Inhibitory concentration of the compound against lipid peroxidation in rat ChEMBL. 15686926

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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