Detailed information for compound 325280

Basic information

Technical information
  • TDR Targets ID: 325280
  • Name: 1-[7-[4-[(E)-ethoxyiminomethyl]phenoxy]heptyl ]-3-pyridin-4-ylimidazolidin-2-one
  • MW: 424.536 | Formula: C24H32N4O3
  • H donors: 0 H acceptors: 2 LogP: 4.05 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCO/N=C/c1ccc(cc1)OCCCCCCCN1CCN(C1=O)c1ccncc1
  • InChi: 1S/C24H32N4O3/c1-2-31-26-20-21-8-10-23(11-9-21)30-19-7-5-3-4-6-16-27-17-18-28(24(27)29)22-12-14-25-15-13-22/h8-15,20H,2-7,16-19H2,1H3/b26-20+
  • InChiKey: STZAVDGXPVHUHJ-LHLOQNFPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[7-[4-[(E)-ethoxyiminomethyl]phenoxy]heptyl]-3-(4-pyridyl)imidazolidin-2-one
  • 1-[7-[4-[(E)-ethoxyiminomethyl]phenoxy]heptyl]-3-(4-pyridyl)-2-imidazolidinone
  • 1-[7-[4-[(E)-ethoxyiminomethyl]phenoxy]heptyl]-3-pyridin-4-yl-imidazolidin-2-one
  • 1-[7-[4-[(E)-ethyloximinomethyl]phenoxy]heptyl]-3-(4-pyridyl)-2-imidazolidinone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0305 0.0304
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0011 0.0009
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0068 0.019 0.0586
Brugia malayi Trypsin family protein 0.0055 0.0141 0.0139
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Trypanosoma brucei Calpain-like protein 1.1 0.0238 0.0839 0.1437
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0174 0.0286
Echinococcus multilocularis Glycosyl transferase, family 35 0.0107 0.034 0.0338
Entamoeba histolytica glycogen phosphorylase, putative 0.0107 0.034 0.1052
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0134 0.044 0.0439
Leishmania major cathepsin L-like protease 0.0858 0.3214 0.5517
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.3026
Loa Loa (eye worm) ctsf protein 0.0858 0.3214 0.3214
Echinococcus multilocularis inhibitor of apoptosis protein 0.0134 0.044 0.0439
Loa Loa (eye worm) beta-lactamase 0.0035 0.0063 0.0063
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.3026
Plasmodium vivax proteasome subunit beta type-1, putative 0.0068 0.019 0.0586
Toxoplasma gondii microneme protein, putative 0.0029 0.0039 0.0064
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0091 0.0091
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.081 0.3027 0.3026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0019
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0068 0.019 0.0323
Trypanosoma cruzi centrin, putative 0.0134 0.0443 0.0442
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0107 0.0449
Loa Loa (eye worm) histone deacetylase 1 0.0088 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0008
Brugia malayi hypothetical protein 0.0055 0.0141 0.0139
Leishmania major protein kinase, putative 0.0131 0.043 0.0735
Mycobacterium ulcerans proteasome PrcB 0.0088 0.0265 0.1126
Onchocerca volvulus 0.0858 0.3214 0.5512
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0106 0.0104
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0219 0.0768 0.0766
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0238 0.0839 0.2311
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0264 0.0725
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0219 0.0768 0.2386
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0057 0.0057
Trypanosoma brucei histone deacetylase 3 0.0098 0.0305 0.0522
Brugia malayi Cell death protein 3 precursor 0.0061 0.0163 0.0161
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0084 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0079 0.0214
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Trypanosoma brucei Calpain-like protein 1.2 0.0238 0.0839 0.1437
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0014 0.0013
Brugia malayi Cathepsin L-like precursor 0.0599 0.2222 0.2221
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0011 0.0009
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0858 0.3214 0.3213
Loa Loa (eye worm) hypothetical protein 0.0219 0.0768 0.0768
Trypanosoma brucei histone deacetylase 1 0.0088 0.0264 0.0451
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0039 0.0064
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0063 0.017
Giardia lamblia Histone deacetylase 0.0088 0.0264 0.0725
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0084 0.0083
Brugia malayi MH2 domain containing protein 0.0239 0.0844 0.0842
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0084 0.0083
Trichomonas vaginalis calpain, putative 0.0238 0.0839 0.2311
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0063
Trichomonas vaginalis calmodulin, putative 0.0131 0.043 0.1182
Brugia malayi cathepsin L-like precursor 0.0599 0.2222 0.2221
Brugia malayi Heterochromatin protein 1 0.007 0.0197 0.0196
Trichomonas vaginalis calcium binding protein, putative 0.0131 0.043 0.1182
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0084 0.0083
Trypanosoma cruzi I/6 autoantigen, putative 0.0131 0.043 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0084 0.0228
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0011 0.0009
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0305 0.0304
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0084 0.0083
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0265 0.0263
Echinococcus granulosus chromobox protein 1 0.007 0.0197 0.0196
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0629 0.2338 0.2337
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0011 0.0009
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0107 0.0105
Trypanosoma cruzi calmodulin, putative 0.0131 0.043 0.0428
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2632 1 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.0039
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0131 0.043 0.0428
Leishmania major hypothetical protein, conserved 0.0238 0.0839 0.1437
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Schistosoma mansoni hypothetical protein 0.0044 0.0099 0.0097
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.0844 0.0844
Brugia malayi fibroinase precursor 0.0219 0.0768 0.0766
Loa Loa (eye worm) hypothetical protein 0.0061 0.0163 0.0163
Trypanosoma brucei hypothetical protein, conserved 0.0131 0.043 0.0735
Echinococcus granulosus transmembrane protease serine 3 0.0055 0.0141 0.0139
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0511 0.1884 0.1883
Loa Loa (eye worm) hypothetical protein 0.0219 0.0768 0.0768
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0011 0.0009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.3026
Echinococcus granulosus EF hand domain containing family member A2 0.0133 0.0439 0.0437
Onchocerca volvulus Peroxidase homolog 0.0064 0.0174 0.0286
Onchocerca volvulus 0.0029 0.0039 0.0054
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0238 0.0839 0.2311
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0084 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0011 0.0011
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Echinococcus multilocularis glycogen phosphorylase 0.0107 0.034 0.0338
Leishmania major phospholipase c-like protein 0.0131 0.043 0.0735
Schistosoma mansoni cathepsin s 0.0259 0.0921 0.0919
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0039 0.0064
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0011 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0958 0.3595 0.3594
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0084 0.0084
Entamoeba histolytica cysteine protease, putative 0.0219 0.0768 0.2386
Echinococcus granulosus cathepsin L cysteine proteinase 0.0858 0.3214 0.3213
Brugia malayi Trypsin-like protease protein 5 0.0055 0.0141 0.0139
Trypanosoma brucei calpain-like protein, putative 0.081 0.3027 0.5195
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0858 0.3214 0.887
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0091 0.0246
Leishmania major cysteine peptidase A (CPA) 0.0858 0.3214 0.5517
Entamoeba histolytica cysteine protease, putative 0.0219 0.0768 0.2386
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0008 0.0006
Trypanosoma cruzi cysteine proteinase, putative 0.0478 0.176 0.1758
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0858 0.3214 0.3213
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0008 0.0016
Trypanosoma cruzi oligopeptidase b 0.0629 0.2338 0.2337
Toxoplasma gondii histone deacetylase HDAC1 0.0098 0.0305 0.0522
Loa Loa (eye worm) hypothetical protein 0.0068 0.0188 0.0188
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0011 0.0009
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Giardia lamblia Cathepsin B precursor 0.0965 0.3623 1
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0011 0.0009
Schistosoma mansoni memapsin-2 (A01 family) 0.0456 0.1673 0.1672
Echinococcus granulosus glycogen phosphorylase 0.0107 0.034 0.0338
Leishmania major calcineurin B subunit, putative 0.0131 0.043 0.0735
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0187 0.0643 0.0641
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0076 0.0218 0.0217
Entamoeba histolytica calpain large subunit domain III containing protein 0.0572 0.2117 0.6586
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0088 0.0265 0.0726
Leishmania major cathepsin L-like protease 0.0958 0.3595 0.6171
Plasmodium vivax serine-repeat antigen (SERA) 0.0219 0.0768 0.2386
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2632 1 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0265 0.0263
Entamoeba histolytica cysteine proteinase, putative 0.0478 0.176 0.5473
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0039 0.0064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0965 0.3623 0.3622
Schistosoma mansoni gamma-secretase subunit aph-1 0.0249 0.0882 0.088
Loa Loa (eye worm) histone deacetylase 0.0098 0.0305 0.0305
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0026 0.0042
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0039 0.0064
Echinococcus granulosus histone deacetylase 6 0.0098 0.0305 0.0304
Leishmania major centrin, putative 0.0131 0.043 0.0735
Echinococcus multilocularis endothelin converting enzyme 1 0.0091 0.0279 0.0277
Brugia malayi Histone deacetylase 1 0.0088 0.0264 0.0262
Echinococcus multilocularis calpain family protein 1, d 0.1588 0.6004 0.6004
Schistosoma mansoni neprilysin-2 (M13 family) 0.0046 0.0106 0.0104
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0219 0.0768 0.0766
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0382 0.1391 0.1389
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0084 0.0083
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0277 0.0989 0.0988
Trypanosoma cruzi cysteine proteinase, putative 0.0478 0.176 0.1758
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.0643 0.0641
Onchocerca volvulus 0.0029 0.0039 0.0054
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0068 0.019 0.052
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Toxoplasma gondii centrin, putative 0.0131 0.043 0.0735
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0238 0.0839 0.0837
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0011 0.0009
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0264 0.0725
Schistosoma mansoni hypothetical protein 0.0238 0.0839 0.0837
Echinococcus granulosus endothelin converting enzyme 1 0.0091 0.0279 0.0277
Onchocerca volvulus 0.0131 0.043 0.0726
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0068 0.019 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0008 0.0016
Brugia malayi Cathepsin L-like precursor 0.0858 0.3214 0.3213
Trypanosoma cruzi centrin-3 0.0134 0.0443 0.0442
Brugia malayi Papain family cysteine protease containing protein 0.0219 0.0768 0.0766
Loa Loa (eye worm) glycogen phosphorylase 0.0107 0.034 0.034
Brugia malayi EF hand family protein 0.0131 0.043 0.0428
Loa Loa (eye worm) hypothetical protein 0.0134 0.044 0.044
Echinococcus multilocularis programmed cell death protein 0.0134 0.0443 0.0442
Trypanosoma brucei centrin-3 0.0134 0.0443 0.0758
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0174 0.0174
Trichomonas vaginalis calcineurin B subunit, putative 0.0133 0.0439 0.1206
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.0039
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0026 0.0076
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0084 0.0083
Schistosoma mansoni centrin-related 0.0131 0.043 0.0428
Echinococcus granulosus Dipeptidyl peptidase 9 0.0277 0.0989 0.0988
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0277 0.0989 0.1696
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0273 0.0271
Toxoplasma gondii proteasome subunit beta type, putative 0.0088 0.0265 0.0452
Brugia malayi Papain family cysteine protease containing protein 0.0478 0.176 0.1758
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0091 0.0089
Mycobacterium ulcerans lipase LipD 0.0035 0.0063 0.0264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Trypanosoma cruzi 20S proteasome subunit 0.0042 0.0091 0.0089
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0423 0.0422
Echinococcus granulosus cathepsin b 0.2632 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0768 0.2116
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0965 0.3623 0.6219
Trypanosoma cruzi cysteine peptidase, putative 0.0259 0.0921 0.0919
Echinococcus granulosus chromobox protein 1 0.007 0.0197 0.0196
Brugia malayi cathepsin L-like cysteine proteinase 0.0219 0.0768 0.0766
Entamoeba histolytica cysteine proteinase, putative 0.0858 0.3214 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0219 0.0768 0.2116
Brugia malayi histone deacetylase 3 (HD3) 0.0088 0.0264 0.0262
Brugia malayi calpain 5 0.0238 0.0839 0.0837
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0084 0.0083
Echinococcus granulosus tissue type plasminogen activator 0.0044 0.0099 0.0097
Onchocerca volvulus 0.0219 0.0768 0.1307
Trypanosoma cruzi cysteine peptidase, putative 0.0478 0.176 0.1758
Loa Loa (eye worm) hypothetical protein 0.1922 0.7283 0.7283
Trypanosoma brucei centrin, putative 0.0131 0.043 0.0735
Plasmodium vivax unspecified product 0.0259 0.0921 0.2861
Brugia malayi cathepsin F-like cysteine proteinase 0.0259 0.0921 0.0919
Brugia malayi beta-lactamase 0.0035 0.0063 0.0062
Onchocerca volvulus 0.0858 0.3214 0.5512
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0011 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Loa Loa (eye worm) histone deacetylase 7A 0.0098 0.0305 0.0305
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0174 0.0173
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Onchocerca volvulus 0.0133 0.0439 0.0741
Leishmania major histone deacetylase, putative 0.0098 0.0305 0.0522
Leishmania major hypothetical protein, conserved 0.0025 0.0026 0.0042
Onchocerca volvulus 0.0045 0.0102 0.0163
Onchocerca volvulus 0.0134 0.044 0.0744
Toxoplasma gondii aldehyde dehydrogenase 0.0129 0.0423 0.0724
Trypanosoma cruzi kinesin, putative 0.0572 0.2117 0.2116
Onchocerca volvulus 0.0052 0.0129 0.0209
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1541 0.5825 0.5824
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0011 0.0011
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0088 0.0265 0.0265
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0107 0.0205
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0219 0.0768 0.2386
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.229 0.8693 0.8693
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0042 0.0091 0.0089
Trypanosoma brucei calpain-like protein, putative 0.081 0.3027 0.5195
Loa Loa (eye worm) hypothetical protein 0.0187 0.0643 0.0643
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0187 0.0643 0.1771
Leishmania major cathepsin L-like protease 0.0858 0.3214 0.5517
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0174 0.0172
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0011 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trichomonas vaginalis centrin, putative 0.0131 0.043 0.1182
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0219 0.0768 0.2386
Plasmodium falciparum histone deacetylase, putative 0.0098 0.0305 0.0945
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Toxoplasma gondii hypothetical protein 0.0187 0.0643 0.1101
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0148 0.0252
Brugia malayi carbohydrate phosphorylase 0.0107 0.034 0.0338
Brugia malayi Peptidase family M13 containing protein 0.0091 0.0279 0.0277
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Plasmodium falciparum cysteine repeat modular protein 1 0.0044 0.0099 0.0303
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0063
Entamoeba histolytica cysteine proteinase 1, putative 0.0478 0.176 0.5473
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0219 0.0768 0.0766
Echinococcus multilocularis calpain 0.081 0.3027 0.3026
Brugia malayi Papain family cysteine protease containing protein 0.0219 0.0768 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0084 0.0083
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0174 0.0173
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0088 0.0265 0.0515
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0187 0.0643 0.1101
Giardia lamblia Cathepsin L precursor 0.0219 0.0768 0.2116
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0002 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0273 0.0271
Onchocerca volvulus 0.0076 0.0218 0.0362
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0423 0.1805
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0174 0.0174
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0238 0.0839 0.0837
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Entamoeba histolytica calpain family cysteine protease, putative 0.0238 0.0839 0.2605
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.1511 0.1509
Loa Loa (eye worm) TK/ROR protein kinase 0.0044 0.0099 0.0099
Brugia malayi cathepsin L precursor 0.0219 0.0768 0.0766
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0063 0.017
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0011 0.0009
Echinococcus multilocularis gamma secretase subunit aph 1 0.0249 0.0882 0.088
Trypanosoma brucei calpain-like protein, putative 0.081 0.3027 0.5195
Plasmodium falciparum serine repeat antigen 6 0.0219 0.0768 0.2386
Loa Loa (eye worm) calpain 0.081 0.3027 0.3027
Toxoplasma gondii hypothetical protein 0.0029 0.0039 0.0064
Echinococcus granulosus cathepsin L cysteine protease 0.0478 0.176 0.1758
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0084 0.0083
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0011 0.0009
Giardia lamblia Cathepsin L precursor 0.0219 0.0768 0.2116
Loa Loa (eye worm) hypothetical protein 0.0069 0.0194 0.0194
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.0039
Onchocerca volvulus 0.0858 0.3214 0.5512
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0011 0.0009
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0187 0.0643 0.0641
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0088 0.0265 0.0452
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.081 0.3027 0.3026
Echinococcus multilocularis calcium uptake protein 1 0.0133 0.0439 0.0437
Entamoeba histolytica prolyl oligopeptidase family protein 0.0187 0.0643 0.1996
Onchocerca volvulus 0.0055 0.0141 0.0229
Plasmodium falciparum calpain 0.0238 0.0839 0.2605
Giardia lamblia Cathepsin L precursor 0.0219 0.0768 0.2116
Entamoeba histolytica histone deacetylase, putative 0.0088 0.0264 0.0817
Brugia malayi Serine carboxypeptidase S28 family protein 0.0021 0.0008 0.0006
Toxoplasma gondii calmodulin CAM1 0.0133 0.0439 0.075
Plasmodium falciparum serine repeat antigen 5 0.0219 0.0768 0.2386
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0858 0.3214 0.887
Trypanosoma cruzi Aph-1 protein, putative 0.0097 0.03 0.0299
Onchocerca volvulus 0.0505 0.1861 0.3186
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0187 0.0643 0.1996
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0055 0.0141 0.0139
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0238 0.0839 0.2311
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0091 0.0089
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0277 0.0989 0.0988
Brugia malayi Proteasome A-type and B-type family protein 0.0088 0.0265 0.0263
Leishmania major calmodulin, putative 0.0131 0.043 0.0735
Onchocerca volvulus 0.0035 0.0063 0.0096
Mycobacterium tuberculosis Conserved protein 0.0035 0.0063 0.0121
Brugia malayi Cathepsin L-like precursor 0.0858 0.3214 0.3213
Trichomonas vaginalis calmodulin, putative 0.0131 0.043 0.1182
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0305 0.0304
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0219 0.0768 0.0766
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0478 0.176 0.4854
Loa Loa (eye worm) hypothetical protein 0.0131 0.043 0.043
Brugia malayi nuclear hormone receptor 0.0021 0.0011 0.0009
Brugia malayi proteasome subunit beta type 1 0.0068 0.019 0.0188
Mycobacterium ulcerans zinc metalloprotease 0.0091 0.0279 0.1187
Schistosoma mansoni hypothetical protein 0.0413 0.1511 0.1509
Trichomonas vaginalis calmodulin, putative 0.0134 0.0443 0.1219
Mycobacterium ulcerans beta-lactamase 0.0035 0.0063 0.0264
Echinococcus multilocularis EF hand domain containing family member A2 0.0131 0.043 0.0428
Entamoeba histolytica cysteine protease, putative 0.0219 0.0768 0.2386
Echinococcus multilocularis tumor protein p63 0.0358 0.1297 0.1296
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0011 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0026 0.0024
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Onchocerca volvulus 0.0035 0.0063 0.0096
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0219 0.0768 0.2386
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Echinococcus granulosus histone deacetylase 6 0.0105 0.0329 0.0327
Leishmania major calmodulin, putative 0.0131 0.043 0.0735
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0238 0.0839 0.0837
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0219 0.0768 0.0768
Trypanosoma brucei caltractin, putative 0.0134 0.0443 0.0758
Entamoeba histolytica hypothetical protein 0.0041 0.0084 0.0257
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0305 0.0304
Onchocerca volvulus Deterin homolog 0.0134 0.044 0.0744
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0423 0.1805
Loa Loa (eye worm) calpain family protein 1 0.2159 0.8193 0.8193
Trypanosoma brucei histone deacetylase, putative 0.0098 0.0305 0.0522
Trypanosoma cruzi cysteine peptidase, putative 0.0858 0.3214 0.3213
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0063 0.0121
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.081 0.3027 0.3026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Leishmania major cathepsin L-like protease 0.0958 0.3595 0.6171
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.5195
Loa Loa (eye worm) hypothetical protein 0.0045 0.0102 0.0102
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Echinococcus granulosus neurocalcin 0.0131 0.043 0.0428
Brugia malayi hypothetical protein 0.0061 0.0163 0.0161
Loa Loa (eye worm) trypsin family protein 0.0055 0.0141 0.0141
Schistosoma mansoni centrin 0.0131 0.043 0.0428
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0599 0.2222 0.6132
Onchocerca volvulus 0.0029 0.0039 0.0054
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Giardia lamblia Cathepsin B precursor 0.0965 0.3623 1
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0174 0.0286
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0084 0.0084
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0382 0.1391 0.1389
Loa Loa (eye worm) hypothetical protein 0.0187 0.0643 0.0643
Onchocerca volvulus 0.0031 0.0047 0.0068
Onchocerca volvulus 0.0055 0.0141 0.0229
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0084 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0629 0.2338 0.4012
Plasmodium falciparum centrin-1 0.0131 0.043 0.1332
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0011 0.0009
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0084 0.0083
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0084 0.0084
Giardia lamblia Cathepsin L-like protease 0.0219 0.0768 0.2116
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0238 0.0839 0.0837
Mycobacterium tuberculosis Probable peptidase 0.0629 0.2338 0.4573
Schistosoma mansoni calpain C (C02 family) 0.081 0.3027 0.3026
Entamoeba histolytica calmodulin, putative 0.0131 0.043 0.1332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Onchocerca volvulus Cathepsin L homolog 0.0219 0.0768 0.1307
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0063 0.0264
Trichomonas vaginalis esterase, putative 0.0035 0.0063 0.017
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0131 0.043 0.1182
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0011 0.0009
Schistosoma mansoni glycogen phosphorylase 0.0107 0.034 0.0338
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0008 0.0016
Leishmania major proteasome beta 2 subunit, putative 0.0042 0.0091 0.0153
Echinococcus granulosus caspase 2 0.0061 0.0163 0.0161
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0129 0.0423 0.0724
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Schistosoma mansoni cathepsin F (C01 family) 0.0858 0.3214 0.3213
Trypanosoma cruzi oligopeptidase b 0.0629 0.2338 0.2337
Brugia malayi calpain family protein 1 0.2159 0.8193 0.8192
Onchocerca volvulus 0.0858 0.3214 0.5512
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0019
Echinococcus granulosus calpain 0.081 0.3027 0.3026
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0084 0.0083
Loa Loa (eye worm) prolyl oligopeptidase 0.0187 0.0643 0.0643
Mycobacterium leprae probable zinc metalloprotease 0.0091 0.0279 0.0948
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0788 0.1538
Echinococcus granulosus cpg binding protein 0.0031 0.0046 0.0045
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0084 0.0083
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0091 0.0246
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0084 0.0083
Schistosoma mansoni hypothetical protein 0.0055 0.0141 0.0139
Trichomonas vaginalis calpain, putative 0.0238 0.0839 0.2311
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0273 0.0271
Schistosoma mansoni Mername-AA248 (C02 family) 0.081 0.3027 0.3026
Trichomonas vaginalis glycogen phosphorylase, putative 0.0107 0.034 0.0933
Plasmodium falciparum serine repeat antigen 7 0.0219 0.0768 0.2386
Echinococcus multilocularis microtubule associated protein 2 0.146 0.5518 0.5517
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0858 0.3214 0.3214
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0063 0.017
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0131 0.043 0.1332
Toxoplasma gondii cathepsin CPL 0.0858 0.3214 0.5517
Brugia malayi hypothetical protein 0.0041 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0041 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0219 0.0768 0.2116
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0091 0.0143
Brugia malayi Trypsin family protein 0.0055 0.0141 0.0139
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0039 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0099 0.0097
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Echinococcus granulosus enteropeptidase 0.0055 0.0141 0.0139
Trypanosoma brucei Aph-1 protein, putative 0.0097 0.03 0.0513
Giardia lamblia Cathepsin B precursor 0.0219 0.0768 0.2116
Onchocerca volvulus 0.0055 0.0141 0.0229
Loa Loa (eye worm) hypothetical protein 0.0134 0.044 0.044
Toxoplasma gondii peptidase family M13 protein 0.0091 0.0279 0.0476
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0423 0.0422
Entamoeba histolytica prolyl oligopeptidase family protein 0.0187 0.0643 0.1996
Onchocerca volvulus 0.0055 0.0141 0.0229
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0277 0.0989 0.0988
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Plasmodium falciparum serine repeat antigen 4 0.0219 0.0768 0.2386
Brugia malayi steroid hormone receptor 0.0021 0.0011 0.0009
Echinococcus granulosus proteasome prosome macropain 0.0088 0.0265 0.0263
Brugia malayi hypothetical protein 0.0025 0.0026 0.0024
Giardia lamblia Cathepsin B precursor 0.0965 0.3623 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0063
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0144 0.0144
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0063 0.0121
Trypanosoma cruzi calmodulin, putative 0.0131 0.043 0.0428
Brugia malayi PXA domain containing protein 0.0041 0.0084 0.0083
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0107 0.0326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0011 0.0011
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0131 0.043 0.0428
Brugia malayi prolyl oligopeptidase family protein 0.1541 0.5825 0.5824
Echinococcus granulosus cathepsin l cysteine peptidase 0.0858 0.3214 0.3213
Loa Loa (eye worm) hypothetical protein 0.0238 0.0839 0.0839
Brugia malayi peptidase family M13 containing protein 0.0022 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0219 0.0768 0.0768
Plasmodium falciparum histone deacetylase 1 0.0088 0.0264 0.0817
Onchocerca volvulus 0.0055 0.0141 0.0229
Schistosoma mansoni calmodulin 0.0131 0.043 0.0428
Brugia malayi Cathepsin L-like precursor 0.0858 0.3214 0.3213
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0019
Trypanosoma brucei protein I/6 0.0131 0.043 0.0735
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0238 0.0839 0.0837
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0044 0.0099 0.0099
Plasmodium vivax hypothetical protein, conserved 0.0187 0.0643 0.1996
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0219 0.0768 0.2386
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0021 0.0008 0.0006
Onchocerca volvulus 0.016 0.0541 0.0917
Entamoeba histolytica hypothetical protein, conserved 0.0187 0.0643 0.1996
Loa Loa (eye worm) hypothetical protein 0.0055 0.0141 0.0141
Schistosoma mansoni glycogen phosphorylase 0.0107 0.034 0.0338
Trypanosoma cruzi cysteine peptidase, putative 0.0958 0.3595 0.3594
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0084 0.0083
Schistosoma mansoni calpain-7 (C02 family) 0.081 0.3027 0.3026
Trypanosoma brucei centrin, putative 0.0131 0.043 0.0735
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0238 0.0839 0.2311
Onchocerca volvulus 0.0021 0.0011 0.0006
Onchocerca volvulus 0.0858 0.3214 0.5512
Onchocerca volvulus 0.0061 0.0163 0.0267
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Plasmodium vivax vivapain-2 0.0858 0.3214 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Giardia lamblia Hypothetical protein 0.0133 0.0439 0.1206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0273 0.0271
Schistosoma mansoni reticulocalbin 0.0131 0.043 0.0428
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0088 0.0265 0.0263
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0011 0.0009
Plasmodium falciparum cysteine proteinase falcipain 1 0.0478 0.176 0.5473
Trypanosoma brucei calpain-like protein, putative 0.081 0.3027 0.5195
Loa Loa (eye worm) calmodulin-like protein 0.0131 0.043 0.043
Schistosoma mansoni neuronal calcium sensor 0.0131 0.043 0.0428
Leishmania major oligopeptidase b 0.0629 0.2338 0.4012
Echinococcus granulosus Mastin 0.0055 0.0141 0.0139
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0219 0.0768 0.0766
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0134 0.044 0.0439
Plasmodium falciparum serine repeat antigen 2 0.0219 0.0768 0.2386
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Schistosoma mansoni cpg binding protein 0.0031 0.0046 0.0045
Echinococcus granulosus histone deacetylase 3 0.0088 0.0264 0.0262
Toxoplasma gondii EF hand domain-containing protein 0.0131 0.043 0.0735
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0055 0.0141 0.0141
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0219 0.0768 0.2386
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0219 0.0768 0.2116
Giardia lamblia Cathepsin B precursor 0.0219 0.0768 0.2116
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2632 1 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0084 0.0083
Echinococcus granulosus calpain A 0.081 0.3027 0.3026
Onchocerca volvulus 0.0035 0.0063 0.0096
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0021 0.0008 0.0016
Echinococcus granulosus neuronal calcium sensor 0.0131 0.043 0.0428
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0008
Echinococcus multilocularis cysteine protease 0.0858 0.3214 0.3213
Onchocerca volvulus 0.0064 0.0174 0.0286
Brugia malayi chromobox protein homolog 3 0.0039 0.0079 0.0078
Loa Loa (eye worm) hypothetical protein 0.0069 0.0194 0.0194
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Brugia malayi hypothetical protein 0.016 0.0541 0.0539
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0174 0.0174
Schistosoma mansoni hypothetical protein 0.0171 0.0582 0.058
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.006 0.0059
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0046 0.0106 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0219 0.0768 0.2116
Echinococcus multilocularis tissue type plasminogen activator 0.0044 0.0099 0.0097
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0629 0.2338 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0057 0.0238
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.0092 0.0154
Echinococcus multilocularis cathepsin b 0.2632 1 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0219 0.0768 0.0766
Toxoplasma gondii prolyl endopeptidase 0.1541 0.5825 1
Echinococcus multilocularis chromobox protein 1 0.007 0.0197 0.0196
Echinococcus multilocularis neuronal calcium sensor 0.0131 0.043 0.0428
Onchocerca volvulus 0.0029 0.0039 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0011 0.0009
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0052 0.0126 0.0125
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0063 0.0063
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.081 0.3027 0.3026
Loa Loa (eye worm) hypothetical protein 0.0219 0.0768 0.0768
Echinococcus granulosus calpain A 0.2293 0.8702 0.8702
Trypanosoma cruzi conserved protein 0.0238 0.0839 0.0837
Onchocerca volvulus Prolyl endopeptidase homolog 0.1541 0.5825 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0174 0.0174
Loa Loa (eye worm) cathepsin B 0.0965 0.3623 0.3623
Giardia lamblia Cysteine protease 0.0219 0.0768 0.2116
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0063
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0039 0.0039
Echinococcus multilocularis calbindin 32 0.0133 0.0439 0.0437
Onchocerca volvulus 0.0052 0.0126 0.0204
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0273 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0219 0.0768 0.2116
Schistosoma mansoni calpain-2 (C02 family) 0.0238 0.0839 0.0837
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0264 0.0725
Schistosoma mansoni cpg binding protein 0.0031 0.0046 0.0045
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0039 0.0064
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0174 0.0173
Loa Loa (eye worm) hypothetical protein 0.0091 0.0279 0.0279
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0084 0.0083
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0068 0.019 0.0188
Loa Loa (eye worm) hypothetical protein 0.0069 0.0194 0.0194
Trypanosoma cruzi I/6 autoantigen, putative 0.0131 0.043 0.0428
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0133 0.0439 0.0437
Toxoplasma gondii hypothetical protein 0.0238 0.0839 0.1437
Schistosoma mansoni cathepsin F (C01 family) 0.0599 0.2222 0.2221
Loa Loa (eye worm) hypothetical protein 0.0091 0.0275 0.0275
Echinococcus granulosus cysteine protease 0.0478 0.176 0.1758
Plasmodium falciparum histone deacetylase 2 0.0098 0.0305 0.0945
Leishmania major hypothetical protein, conserved 0.0044 0.0099 0.0167
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0277 0.0989 0.1696
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0264 0.0725
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0036 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0599 0.2222 0.6132
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0699 0.2603 0.2602
Echinococcus granulosus programmed cell death protein 0.0134 0.0443 0.0442
Loa Loa (eye worm) hypothetical protein 0.0055 0.0141 0.0141
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0629 0.2338 0.4012
Onchocerca volvulus 0.0055 0.0141 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0187 0.0643 0.1771
Schistosoma mansoni neuronal calcium sensor 0.0131 0.043 0.0428
Brugia malayi Cytochrome P450 family protein 0.0034 0.0057 0.0056
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0131 0.043 0.0735
Onchocerca volvulus 0.0029 0.0039 0.0054
Echinococcus multilocularis survival motor neuron protein 1 0.0253 0.0897 0.0895
Trichomonas vaginalis calcium binding protein, putative 0.0131 0.043 0.1182
Brugia malayi Papain family cysteine protease containing protein 0.0219 0.0768 0.0766
Echinococcus granulosus EF hand domain containing family member A2 0.0131 0.043 0.0428
Leishmania major centrin, putative 0.0131 0.043 0.0735
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0063 0.0121
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0063 0.0264
Brugia malayi Peroxidasin 0.0064 0.0174 0.0172
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0039 0.0039
Brugia malayi Trypsin family protein 0.0055 0.0141 0.0139
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0021 0.0008 0.0006
Plasmodium vivax SET domain protein, putative 0.0064 0.0174 0.0538
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0511 0.1884 0.1883
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0057 0.0095
Loa Loa (eye worm) fibroinase 0.0858 0.3214 0.3214
Trichomonas vaginalis calmodulin, putative 0.0131 0.043 0.1182
Brugia malayi Trypsin family protein 0.0055 0.0141 0.0139
Echinococcus granulosus calpain 7 C02 family 0.081 0.3027 0.3026
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0219 0.0768 0.0766
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0068 0.019 0.0323
Trypanosoma cruzi prolyl endopeptidase 0.1541 0.5825 0.5824
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0057 0.0057
Plasmodium falciparum peptidase, putative 0.0187 0.0643 0.1996
Loa Loa (eye worm) hypothetical protein 0.0599 0.2222 0.2222
Loa Loa (eye worm) EF hand family protein 0.0131 0.043 0.043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0219 0.0768 0.2116
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.081 0.3027 0.3026
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0011 0.0009
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Echinococcus multilocularis cathepsin b 0.2632 1 1
Echinococcus multilocularis histone deacetylase 1 0.0088 0.0264 0.0262
Onchocerca volvulus 0.0064 0.0174 0.0286
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Echinococcus multilocularis prolyl endopeptidase 0.1541 0.5825 0.5824
Trypanosoma brucei proteasome beta 6 subunit 0.0068 0.019 0.0323
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0041 0.0084 0.0084
Schistosoma mansoni chromobox protein 0.007 0.0197 0.0196
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0011 0.0009
Brugia malayi Cathepsin L-like precursor 0.0858 0.3214 0.3213
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0084 0.0083
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0134 0.044 0.0439
Toxoplasma gondii cathepsin CPC2 0.0219 0.0768 0.1316
Echinococcus multilocularis geminin 0.0171 0.0582 0.058
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0088 0.0265 0.0726
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0011 0.0009
Leishmania major calmodulin-like protein 0.0131 0.043 0.0735
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0039 0.0064
Trichomonas vaginalis calmodulin, putative 0.0131 0.043 0.1182
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0249 0.0882 0.0882
Schistosoma mansoni histone deacetylase hda2 0.0105 0.0329 0.0327
Schistosoma mansoni cathepsin F (C01 family) 0.0858 0.3214 0.3213
Plasmodium falciparum serine repeat antigen 8 0.0219 0.0768 0.2386
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0057 0.0057
Echinococcus multilocularis calpain 7 (C02 family) 0.081 0.3027 0.3026
Onchocerca volvulus Cathepsin L homolog 0.0858 0.3214 0.5512
Trichomonas vaginalis chromobox protein, putative 0.007 0.0197 0.054
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0131 0.043 0.1182
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0273 0.0273
Onchocerca volvulus Peroxidase homolog 0.0064 0.0174 0.0286
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0055 0.0141 0.0139
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0163 0.0161
Trichomonas vaginalis glycogen phosphorylase, putative 0.0107 0.034 0.0933
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0219 0.0768 0.0766
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Entamoeba histolytica calcium binding family protein 0.0131 0.043 0.1332
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0131 0.043 0.0428
Echinococcus multilocularis calpain A 0.2293 0.8702 0.8702
Loa Loa (eye worm) hypothetical protein 0.0068 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0599 0.2222 0.2222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0219 0.0768 0.2116
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0011 0.0009
Brugia malayi Cytochrome P450 family protein 0.0055 0.0141 0.0139
Echinococcus multilocularis transmembrane protease serine 3 0.0055 0.0141 0.0139
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0131 0.043 0.0428
Trichomonas vaginalis calcium binding proteins, putative 0.0131 0.043 0.1182
Trypanosoma brucei I/6 autoantigen 0.0131 0.043 0.0735
Echinococcus multilocularis cathepsin L cysteine protease 0.0858 0.3214 0.3213
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Loa Loa (eye worm) hypothetical protein 0.1541 0.5825 0.5825
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0011 0.0009
Leishmania major hypothetical protein, conserved 0.0131 0.043 0.0735
Trypanosoma cruzi calmodulin, putative 0.0131 0.043 0.0428
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0084 0.0083
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0026 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0133 0.0439 0.136
Schistosoma mansoni calpain-7 (C02 family) 0.081 0.3027 0.3026
Onchocerca volvulus Cathepsin F homolog 0.0858 0.3214 0.5512
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0129 0.0423 0.0825
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0219 0.0768 0.2386
Trypanosoma brucei histone deacetylase 4 0.0098 0.0305 0.0522
Trichomonas vaginalis calmodulin, putative 0.0131 0.043 0.1182
Leishmania major programmed cell death 6 protein-like protein 0.0131 0.043 0.0735
Onchocerca volvulus Cathepsin L homolog 0.0858 0.3214 0.5512
Entamoeba histolytica hypothetical protein 0.0041 0.0084 0.0257
Leishmania major calmodulin-like protein 0.0131 0.043 0.0735
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0219 0.0768 0.2116
Entamoeba histolytica hypothetical protein 0.0219 0.0768 0.2386
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0039 0.0039
Entamoeba histolytica cysteine protease, putative 0.0219 0.0768 0.2386
Trypanosoma cruzi major cysteine proteinase, putative 0.0319 0.1149 0.1148
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0121 0.0119
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0134 0.044 0.0439
Brugia malayi cathepsin F-like cysteine proteinase 0.0219 0.0768 0.0766
Echinococcus multilocularis cysteine protease 0.0858 0.3214 0.3213
Brugia malayi beta-lactamase family protein 0.0035 0.0063 0.0062
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0219 0.0768 0.2116
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0219 0.0768 0.2386
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0084 0.0084
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0629 0.2338 0.2337
Echinococcus multilocularis histone deacetylase 0.0098 0.0305 0.0304
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0174 0.0172
Brugia malayi calcium-binding protein 0.0131 0.043 0.0428
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0174 0.0286
Loa Loa (eye worm) cysteine protease 0.0858 0.3214 0.3214
Entamoeba histolytica cysteine proteinase, putative 0.0599 0.2222 0.6913
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0174 0.0172
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0264 0.0725
Loa Loa (eye worm) hypothetical protein 0.135 0.5095 0.5095
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0091 0.0246
Trichomonas vaginalis calpain, putative 0.0238 0.0839 0.2311
Giardia lamblia Glycogen phosphorylase 0.0107 0.034 0.0933
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1354 0.5111 1
Echinococcus multilocularis enteropeptidase 0.0055 0.0141 0.0139
Echinococcus granulosus geminin 0.0171 0.0582 0.058
Loa Loa (eye worm) hypothetical protein 0.0069 0.0194 0.0194
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0219 0.0768 0.2386
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0011 0.0009
Brugia malayi prolyl oligopeptidase family protein 0.0511 0.1884 0.1883
Echinococcus multilocularis apoptotic protease activating factor 1 0.0061 0.0163 0.0161
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0259 0.0921 0.0919
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0008
Echinococcus multilocularis hypothetical protein 0.081 0.3027 0.3026
Leishmania major histone deacetylase, putative 0.0088 0.0264 0.0451
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0107 0.0326
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0131 0.043 0.1332
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0174 0.0173
Plasmodium vivax centrin-1, putative 0.0131 0.043 0.1332
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0019
Brugia malayi Pre-SET motif family protein 0.0064 0.0174 0.0173
Loa Loa (eye worm) hypothetical protein 0.0599 0.2222 0.2222
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.229 0.8693 0.8693
Trypanosoma brucei oligopeptidase b 0.0629 0.2338 0.4012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0011 0.0011
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.1588 0.6004 0.6004
Brugia malayi Cathepsin L-like precursor 0.0599 0.2222 0.2221
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0063 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0219 0.0768 0.2116
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0219 0.0768 0.2386
Leishmania major calpain family cysteine protease-like protein 0.0238 0.0839 0.1437
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0084 0.0083
Brugia malayi calpain 7 0.081 0.3027 0.3026
Onchocerca volvulus 0.0029 0.0039 0.0054
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0084 0.0083
Schistosoma mansoni cpg binding protein 0.0029 0.004 0.0038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0238 0.0839 0.0837
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0021 0.0008 0.001
Echinococcus multilocularis Mastin 0.0055 0.0141 0.0139
Schistosoma mansoni hypothetical protein 0.0134 0.044 0.0439
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Trypanosoma cruzi cysteine peptidase, putative 0.0958 0.3595 0.3594
Schistosoma mansoni microtubule-associated protein tau 0.146 0.5518 0.5517
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0219 0.0768 0.2116
Plasmodium vivax vivapain-2 0.0858 0.3214 1
Plasmodium falciparum serine repeat antigen 1 0.0219 0.0768 0.2386
Brugia malayi cathepsin Z-like cysteine proteinase 0.0219 0.0768 0.0766
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trichomonas vaginalis centrin, putative 0.0131 0.043 0.1182
Schistosoma mansoni ef hand domain family member A2 0.0131 0.043 0.0428
Entamoeba histolytica glycogen phosphorylase, putative 0.0107 0.034 0.1052
Echinococcus granulosus calbindin 32 0.0133 0.0439 0.0437
Loa Loa (eye worm) hypothetical protein 0.0042 0.0091 0.0091
Plasmodium vivax proteasome subunit beta type-5, putative 0.0088 0.0265 0.0819
Echinococcus granulosus histone deacetylase 1 0.0088 0.0264 0.0262
Brugia malayi Protein kinase domain containing protein 0.0044 0.0099 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0273 0.0271
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0835 0.3125 0.3124
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0022 0.0014 0.0013
Brugia malayi Blistered cuticle protein 3 0.0064 0.0174 0.0172
Toxoplasma gondii preprocathepsin c precursor, putative 0.0219 0.0768 0.1316
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0011 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0141 0.0141
Plasmodium vivax calpain, putative 0.081 0.3027 0.9417
Echinococcus granulosus gamma secretase subunit aph 1 0.0249 0.0882 0.088
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0042 0.0091 0.0277
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0042 0.0091 0.0089
Loa Loa (eye worm) hypothetical protein 0.005 0.0121 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0219 0.0768 0.2116
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0084 0.0083
Plasmodium falciparum proteasome subunit beta type-5 0.0088 0.0265 0.0819
Leishmania major histone deacetylase, putative 0.0098 0.0305 0.0522
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2159 0.8193 0.8192
Loa Loa (eye worm) hypothetical protein 0.0041 0.0084 0.0084
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0197 0.0197
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0091 0.0246
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0187 0.0643 0.1771
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0063 0.017
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0069 0.0194 0.0194
Toxoplasma gondii centrin 0.0131 0.043 0.0735
Loa Loa (eye worm) proteasome subunit beta type 1 0.0068 0.019 0.019
Echinococcus multilocularis caspase 2 0.0061 0.0163 0.0161
Echinococcus granulosus calumenin 0.0133 0.0439 0.0437
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.0039
Entamoeba histolytica calmodulin, putative 0.0131 0.043 0.1332
Echinococcus multilocularis cathepsin L 0.0478 0.176 0.1758
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0511 0.1884 0.3226
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0011 0.0006
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0091 0.0279 0.0543
Loa Loa (eye worm) hypothetical protein 0.0069 0.0194 0.0194
Echinococcus granulosus peroxidasin 0.0064 0.0174 0.0172
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0011 0.0009
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0163 0.0267
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Onchocerca volvulus 0.135 0.5095 0.8745
Loa Loa (eye worm) calpain family protein 1 0.1588 0.6004 0.6004
Mycobacterium ulcerans hypothetical protein 0.0035 0.0063 0.0264
Toxoplasma gondii troponin c, isotype gamma, putative 0.0131 0.043 0.0735
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0091 0.0089
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0011 0.0006
Echinococcus granulosus expressed protein 0.079 0.2952 0.2951
Echinococcus multilocularis calumenin 0.0133 0.0439 0.0437
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0174 0.0172
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0084 0.0083
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0259 0.0921 0.0921
Echinococcus granulosus EF HAND 1 calcium binding site 0.0131 0.043 0.0428
Brugia malayi Cathepsin L-like precursor 0.0858 0.3214 0.3213
Brugia malayi CXXC zinc finger family protein 0.0029 0.004 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.5195
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0219 0.0768 0.2386
Plasmodium vivax vivapain-3 0.0478 0.176 0.5473
Trypanosoma brucei Calpain-like protein 2 0.0238 0.0839 0.1437
Brugia malayi ecdysteroid receptor 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0259 0.0921 0.0921
Brugia malayi Papain family cysteine protease containing protein 0.0478 0.176 0.1758
Brugia malayi beta-lactamase family protein 0.0035 0.0063 0.0062
Echinococcus granulosus survival motor neuron protein 1 0.0253 0.0897 0.0895
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0011 0.0009
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0084 0.0083
Mycobacterium tuberculosis Conserved protein 0.0035 0.0063 0.0121
Brugia malayi calpain 5 0.0572 0.2117 0.2116
Schistosoma mansoni neprilysin 0.0024 0.002 0.0019
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0131 0.043 0.1332
Echinococcus granulosus histone deacetylase 8 0.0042 0.0091 0.0089
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0091 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.043 0.1182
Brugia malayi hypothetical protein 0.0253 0.0897 0.0895
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Brugia malayi prolyl oligopeptidase family protein 0.0277 0.0989 0.0988
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0011 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Giardia lamblia Proteasome subunit beta type 1 0.0068 0.019 0.052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Entamoeba histolytica calcium-binding protein, putative 0.0131 0.043 0.1332
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0277 0.0989 0.1696
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0131 0.043 0.0428
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.0844 0.0844
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0219 0.0768 0.2116
Trypanosoma brucei calmodulin, putative 0.0131 0.043 0.0735
Brugia malayi Cathepsin L-like precursor 0.0259 0.0921 0.0919
Brugia malayi EF hand family protein 0.0133 0.0439 0.0437
Leishmania major hypothetical protein, unknown function 0.0238 0.0839 0.1437
Onchocerca volvulus 0.0064 0.0174 0.0286
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0264 0.0725
Loa Loa (eye worm) histone deacetylase 3 0.0088 0.0264 0.0264
Entamoeba histolytica cysteine proteinase, putative 0.0478 0.176 0.5473
Echinococcus granulosus microtubule associated protein 2 0.146 0.5518 0.5517
Brugia malayi hypothetical protein 0.0041 0.0084 0.0083
Trichomonas vaginalis calcium binding protein, putative 0.0134 0.0443 0.1219
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0134 0.044 0.0439
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0174 0.0172
Loa Loa (eye worm) hypothetical protein 0.0055 0.0141 0.0141
Giardia lamblia Thymus-specific serine protease precursor 0.0021 0.0008 0.0016
Schistosoma mansoni endothelin-converting enzyme-related 0.0022 0.0014 0.0013
Trypanosoma brucei prolyl endopeptidase 0.1541 0.5825 1
Echinococcus granulosus histone deacetylase 7 0.0098 0.0305 0.0304
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0264 0.0262
Trichomonas vaginalis set domain proteins, putative 0.0505 0.186 0.5131
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0187 0.0643 0.1101
Plasmodium vivax proteasome subunit beta type-2, putative 0.0042 0.0091 0.0277
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0068 0.019 0.0586
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0084 0.0083
Giardia lamblia Cathepsin B precursor 0.0219 0.0768 0.2116
Trypanosoma cruzi kinesin, putative 0.0572 0.2117 0.2116
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0036 0.0093
Brugia malayi histone deacetylase 1 (HD1) 0.0088 0.0264 0.0262
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Leishmania major centrin, putative,caltractin, putative 0.0131 0.043 0.0735
Schistosoma mansoni hypothetical protein 0.0171 0.0582 0.058
Schistosoma mansoni hypothetical protein 0.0131 0.043 0.0428
Loa Loa (eye worm) hypothetical protein 0.0088 0.0264 0.0264
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Trypanosoma brucei hypothetical protein 0.0238 0.0839 0.1437
Schistosoma mansoni chromobox protein 0.007 0.0197 0.0196
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Echinococcus multilocularis centrin 2 0.0131 0.043 0.0428
Trypanosoma cruzi caltractin, putative 0.0131 0.043 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0047
Entamoeba histolytica hypothetical protein, conserved 0.0133 0.0439 0.136
Loa Loa (eye worm) hypothetical protein 0.016 0.0541 0.0541
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0063 0.0062
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0599 0.2221 0.2221
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0131 0.043 0.0735
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0014 0.0013
Echinococcus multilocularis EF hand domain containing family member A2 0.0133 0.0439 0.0437
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.043 0.1182
Toxoplasma gondii hypothetical protein 0.0029 0.0039 0.0064
Brugia malayi Papain family cysteine protease containing protein 0.0858 0.3214 0.3213
Echinococcus granulosus calpain 5 0.081 0.3027 0.3026
Entamoeba histolytica cysteine proteinase, putative 0.0478 0.176 0.5473
Echinococcus multilocularis histone deacetylase 7 0.0098 0.0305 0.0304
Schistosoma mansoni neuronal calcium sensor 0.0131 0.043 0.0428
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0063
Leishmania major proteasome beta 5 subunit, putative 0.0088 0.0265 0.0452
Brugia malayi programmed cell death protein 6 0.0131 0.043 0.0428
Brugia malayi Histone deacetylase family protein 0.0098 0.0305 0.0304
Schistosoma mansoni hypothetical protein 0.0131 0.043 0.0428
Brugia malayi calpain D 0.0238 0.0839 0.0837
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0131 0.043 0.0428
Entamoeba histolytica cysteine proteinase, putative 0.0478 0.176 0.5473
Loa Loa (eye worm) hypothetical protein 0.0035 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0965 0.3623 1
Schistosoma mansoni coup transcription factor 0.0021 0.0011 0.0009
Plasmodium vivax histone deacetylase 2, putative 0.0098 0.0305 0.0945
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.5195
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0238 0.0839 0.1437
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0084 0.0084
Brugia malayi Angiotensin-converting enzyme family protein 0.0599 0.2221 0.222
Entamoeba histolytica grainin, putative 0.0133 0.0439 0.136
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0264 0.0725
Loa Loa (eye worm) hypothetical protein 0.0041 0.0084 0.0084
Onchocerca volvulus 0.0029 0.004 0.0056
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0055 0.0141 0.0139
Schistosoma mansoni histone deacetylase 0.0088 0.0264 0.0262
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0188 0.0188
Loa Loa (eye worm) zinc metallopeptidase 4 0.0022 0.0014 0.0014
Trichomonas vaginalis calmodulin-2, putative 0.0131 0.043 0.1182
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0133 0.0439 0.0437
Echinococcus multilocularis glycogen phosphorylase 0.0107 0.034 0.0338
Plasmodium vivax histone deacetylase, putative 0.0042 0.0091 0.0277
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0264 0.0725
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0219 0.0768 0.2386
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0008 0.0016
Entamoeba histolytica prolyl oligopeptidase family protein 0.0187 0.0643 0.1996
Echinococcus granulosus centrin 2 0.0131 0.043 0.0428
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0219 0.0768 0.2116
Trypanosoma brucei calpain, putative 0.0238 0.0839 0.1437
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0091 0.0279 0.0277
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.0039
Onchocerca volvulus 0.0029 0.0039 0.0054
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0858 0.3214 1
Mycobacterium ulcerans hypothetical protein 0.0055 0.0141 0.0596
Giardia lamblia Hypothetical protein 0.0219 0.0768 0.2116
Plasmodium vivax unspecified product 0.0478 0.176 0.5473
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0011 0.0006
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0478 0.176 0.1758
Loa Loa (eye worm) hypothetical protein 0.0068 0.0188 0.0188
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0219 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Plasmodium falciparum serine repeat antigen 3 0.0219 0.0768 0.2386
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0219 0.0768 0.2386
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0079 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Trypanosoma brucei antigen, putative 0.081 0.3027 0.5195
Schistosoma mansoni rab 0.0131 0.043 0.0428
Giardia lamblia Cysteine protease 0.0219 0.0768 0.2116
Brugia malayi hypothetical protein 0.0091 0.0275 0.0274
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0039 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0063 0.0062
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0021 0.0008 0.0006
Echinococcus multilocularis proteasome (prosome, macropain) 0.0088 0.0265 0.0263
Toxoplasma gondii microneme protein MIC4 0.0029 0.0039 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0011 0.0009
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0174 0.0297
Entamoeba histolytica protein kinase, putative 0.0572 0.2117 0.6586
Toxoplasma gondii ABC1 family protein 0.0035 0.0063 0.0106
Loa Loa (eye worm) hypothetical protein 0.0253 0.0897 0.0897
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2632 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0057 0.0056
Entamoeba histolytica cysteine protease, putative 0.0219 0.0768 0.2386
Brugia malayi prolyl oligopeptidase family protein 0.0187 0.0643 0.0641
Trypanosoma brucei cysteine peptidase C (CPC) 0.0965 0.3623 0.6219
Echinococcus granulosus acylamino acid releasing enzyme 0.0187 0.0643 0.0641
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0858 0.3214 0.3214
Leishmania major hypothetical protein, conserved 0.0133 0.0439 0.075
Echinococcus multilocularis calmodulin 0.0131 0.043 0.0428
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0129 0.0423 0.0422
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0478 0.176 0.1758
Toxoplasma gondii cathepsin B 0.0965 0.3623 0.6219
Schistosoma mansoni mitochondrial solute carrier 0.0131 0.043 0.0428
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0022 0.0014 0.0013
Toxoplasma gondii EFHC1, putative 0.0131 0.043 0.0735
Onchocerca volvulus 0.0029 0.0039 0.0054
Trypanosoma brucei cysteine peptidase, putative 0.0238 0.0839 0.1437
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0091 0.0089
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0219 0.0768 0.2116
Giardia lamblia Cathepsin L precursor 0.0219 0.0768 0.2116
Giardia lamblia Alanyl dipeptidyl peptidase 0.0187 0.0643 0.1771
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Entamoeba histolytica cysteine proteinase, putative 0.0858 0.3214 1
Leishmania major histone deacetylase, putative 0.0088 0.0264 0.0451
Brugia malayi proteasome subunit beta type 2 0.0042 0.0091 0.0089
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0084 0.0083
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0088 0.0265 0.0819
Trypanosoma brucei prolyl oligopeptidase, putative 0.0629 0.2338 0.4012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0219 0.0768 0.2116
Echinococcus granulosus inhibitor of apoptosis protein 0.0134 0.044 0.0439
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0106 0.0104
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.081 0.3027 0.5195
Echinococcus granulosus Glycosyl transferase family 35 0.0107 0.034 0.0338
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0063 0.0062
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0057 0.0056
Toxoplasma gondii histone deacetylase HDAC2 0.0088 0.0264 0.0451
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.229 0.8693 0.8693
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0011 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0174 0.0173
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0478 0.176 0.4854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0277 0.0989 0.1696
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0238 0.0839 0.1437
Loa Loa (eye worm) hypothetical protein 0.0055 0.0141 0.0141
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0238 0.0839 0.1437
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0219 0.0768 0.2386
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0084 0.0083
Brugia malayi Cathepsin L-like precursor 0.0858 0.3214 0.3213
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0068 0.019 0.0188
Giardia lamblia Cysteine protease 0.0219 0.0768 0.2116
Echinococcus multilocularis cpg binding protein 0.0031 0.0046 0.0045
Trichomonas vaginalis calmodulin, putative 0.0131 0.043 0.1182
Onchocerca volvulus 0.0858 0.3214 0.5512
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Echinococcus multilocularis chromobox protein 1 0.007 0.0197 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0084 0.0228
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0382 0.1391 0.1389
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0039 0.0064
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trypanosoma brucei Component of motile flagella 41 0.0131 0.043 0.0735
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0238 0.0839 0.0837
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0238 0.0839 0.0837
Echinococcus multilocularis glycoprotein Antigen 5 0.0055 0.0141 0.0139
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0084 0.0083
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0063 0.0062
Brugia malayi calpain family protein 1 0.2159 0.8193 0.8192
Giardia lamblia Cathepsin L-like protease 0.0219 0.0768 0.2116
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0264 0.0725
Brugia malayi histone deacetylase 11 0.0042 0.0091 0.0089
Brugia malayi Kringle domain containing protein 0.0044 0.0099 0.0097
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0021 0.0008 0.0006
Echinococcus granulosus histone deacetylase 0.0098 0.0305 0.0304
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0629 0.2338 1
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0008 0.0018
Brugia malayi Cathepsin L-like cysteine proteinase 0.0599 0.2222 0.2221
Giardia lamblia Hypothetical protein 0.0219 0.0768 0.2116
Giardia lamblia Encystation-specific protease 0.0219 0.0768 0.2116
Leishmania major cathepsin L-like protease 0.0858 0.3214 0.5517
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0219 0.0768 0.2116
Schistosoma mansoni reticulocalbin 0.0133 0.0439 0.0437
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.229 0.8693 0.8693
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0041 0.0084 0.0084
Brugia malayi PXA domain containing protein 0.0041 0.0084 0.0083
Giardia lamblia Cathepsin B precursor 0.0219 0.0768 0.2116
Echinococcus multilocularis calmodulin 0.0131 0.043 0.0428
Echinococcus granulosus apoptotic protease activating factor 1 0.0061 0.0163 0.0161
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0129 0.0129
Echinococcus granulosus glycogen phosphorylase 0.0107 0.034 0.0338
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0091 0.0153
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0039 0.0039
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0423 0.1805
Trypanosoma cruzi Aph-1 protein, putative 0.0097 0.03 0.0299
Echinococcus granulosus calmodulin 0.0131 0.043 0.0428
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Onchocerca volvulus 0.0029 0.0039 0.0054
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1541 0.5825 1
Trypanosoma brucei Calpain-like protein CALP1.3 0.0238 0.0839 0.1437
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0091 0.0089
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.3026
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0219 0.0768 0.0768
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0084 0.0228
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1541 0.5825 0.5824
Trypanosoma brucei histone deacetylase 2 0.0042 0.0091 0.0153
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0084 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0011 0.0011
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0305 0.0304
Echinococcus multilocularis cathepsin L cysteine protease 0.0858 0.3214 0.3213
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0002 0.5
Loa Loa (eye worm) hypothetical protein 0.0091 0.0279 0.0279
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0044 0.0099 0.0303
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0277 0.0989 0.0988
Echinococcus granulosus cathepsin L 0.0219 0.0768 0.0766
Giardia lamblia Proteasome subunit beta type 2 0.0042 0.0091 0.0246
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.081 0.3027 0.5195
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0026 0.0076
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0965 0.3623 0.3622
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Entamoeba histolytica cysteine proteinase 2 0.0478 0.176 0.5473
Echinococcus granulosus calcium uptake protein 1 0.0133 0.0439 0.0437
Toxoplasma gondii histone deacetylase HDAC3 0.0088 0.0264 0.0451
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0273 0.0271
Brugia malayi nuclear receptor NHR-88 0.0021 0.0011 0.0009
Brugia malayi gamma-secretase subunit aph-1 0.0249 0.0882 0.088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Chlamydia trachomatis glycogen phosphorylase 0.0107 0.034 0.5
Onchocerca volvulus Glycogen phosphorylase homolog 0.0107 0.034 0.0571
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0014 0.0013
Schistosoma mansoni calmodulin related calcium binding protein 0.0131 0.043 0.0428
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0088 0.0265 0.0886
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0079
Leishmania major hypothetical protein, conserved 0.0035 0.0063 0.0106
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0008 0.0006
Echinococcus multilocularis programmed cell death protein 0.0134 0.0443 0.0442
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0129 0.0128
Trypanosoma cruzi cruzipain precursor, putative 0.0958 0.3595 0.3594
Loa Loa (eye worm) hypothetical protein 0.0062 0.0167 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Leishmania major kinesin, putative 0.0572 0.2117 0.3633
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0039 0.0064
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0131 0.043 0.0428
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Echinococcus multilocularis expressed protein 0.079 0.2952 0.2951
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0039 0.0064
Loa Loa (eye worm) programmed cell death protein 6 0.0133 0.0439 0.0439
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0011 0.0009
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0055 0.0141 0.0139
Trichomonas vaginalis myosin light chain 1, putative 0.0131 0.043 0.1182
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0478 0.176 0.1758
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0958 0.3595 0.6171
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0858 0.3214 0.887
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Plasmodium vivax unspecified product 0.0219 0.0768 0.2386
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0084 0.0083
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0188 0.0188
Trypanosoma brucei mitochondrial calcium uptake 1 0.0131 0.043 0.0735
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0011 0.0009
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0042 0.0091 0.0277
Toxoplasma gondii cathepsin CPC1 0.0219 0.0768 0.1316
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0219 0.0768 0.2116
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0131 0.043 0.0428
Schistosoma mansoni calpain (C02 family) 0.081 0.3027 0.3026
Loa Loa (eye worm) hypothetical protein 0.0041 0.0084 0.0084
Schistosoma mansoni peroxidasin 0.0064 0.0174 0.0172
Loa Loa (eye worm) hypothetical protein 0.0259 0.0921 0.0921
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0011 0.0011
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0063 0.0121
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0055 0.0141 0.0139
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0264 0.0262
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Plasmodium vivax serine-repeat antigen (SERA) 0.0219 0.0768 0.2386
Plasmodium falciparum cysteine proteinase falcipain 3 0.0858 0.3214 1
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0084 0.0083
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0219 0.0768 0.0768
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0011 0.0009
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0011 0.0009
Echinococcus granulosus cathepsin l1 0.0858 0.3214 0.3213
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0042 0.0091 0.0153
Trypanosoma cruzi cruzipain precursor, putative 0.0259 0.0921 0.0919
Mycobacterium tuberculosis Conserved protein 0.0035 0.0063 0.0121
Trypanosoma brucei calmodulin, putative 0.0133 0.0439 0.075
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.006
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0008 0.0006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0141 0.0139
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0121 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0238 0.0839 0.2311
Giardia lamblia Cathepsin L precursor 0.0219 0.0768 0.2116
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0478 0.176 0.1758
Echinococcus granulosus cathepsin L 0.0478 0.176 0.1758
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0091 0.0279 0.0277
Echinococcus granulosus glycoprotein Antigen 5 0.0055 0.0141 0.0139
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0768 0.2116
Giardia lamblia Cysteine protease 0.0219 0.0768 0.2116
Loa Loa (eye worm) calpain 5 0.0572 0.2117 0.2117
Echinococcus multilocularis histone deacetylase 6 0.0105 0.0329 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0238 0.0839 0.2311
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0084 0.0083
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0174 0.0174
Brugia malayi Pre-SET motif family protein 0.0443 0.1626 0.1624
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0063 0.0106
Echinococcus granulosus cathepsin b 0.2632 1 1
Brugia malayi prolyl oligopeptidase family protein 0.0187 0.0643 0.0641
Echinococcus granulosus cathepsin l1 0.0599 0.2222 0.2221
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0219 0.0768 0.2116
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.1437
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0238 0.0839 0.0837
Plasmodium falciparum serine repeat antigen 9 0.0219 0.0768 0.2386
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0219 0.0768 0.2386
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.0643 0.0641
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0443 0.1626 0.1626
Onchocerca volvulus 0.0029 0.0039 0.0054
Schistosoma mansoni inhibitor of apoptosis protein 0.0134 0.044 0.0439
Giardia lamblia Serine peptidase, putative 0.0021 0.0008 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0084 0.0228
Echinococcus multilocularis neurocalcin 0.0131 0.043 0.0428
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0011 0.0009
Leishmania major cytochrome p450-like protein 0.0034 0.0057 0.0095
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0219 0.0768 0.0766
Plasmodium vivax vivapain-1 0.0478 0.176 0.5473
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.2159 0.8193 0.8193
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0131 0.043 0.0428
Schistosoma mansoni hypothetical protein 0.0034 0.006 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0011 0.0009
Echinococcus multilocularis peroxidasin 0.0064 0.0174 0.0172
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0084 0.0083
Onchocerca volvulus 0.0131 0.043 0.0726
Onchocerca volvulus 0.0029 0.0039 0.0054
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0084 0.0083
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0174 0.0172
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0238 0.0839 0.0837
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0238 0.0839 0.0837
Loa Loa (eye worm) hypothetical protein 0.0091 0.0279 0.0279
Schistosoma mansoni cathepsin C 0.0219 0.0768 0.0766
Trichomonas vaginalis calmodulin, putative 0.0133 0.0439 0.1206
Loa Loa (eye worm) hypothetical protein 0.0055 0.0141 0.0141
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0063 0.0062
Schistosoma mansoni peroxidasin 0.0064 0.0174 0.0172
Echinococcus multilocularis calpain 5 0.081 0.3027 0.3026
Onchocerca volvulus 0.0858 0.3214 0.5512
Trichomonas vaginalis calcium binding protein, putative 0.0131 0.043 0.1182
Plasmodium vivax histone deacetylase 1, putative 0.0088 0.0264 0.0817
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0084 0.0083
Leishmania major cathepsin L-like protease 0.0858 0.3214 0.5517
Trypanosoma cruzi centrin, putative 0.0134 0.0443 0.0442
Trichomonas vaginalis calmodulin, putative 0.0131 0.043 0.1182
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0219 0.0768 0.2116
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0107 0.0326
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0008
Leishmania major i/6 autoantigen-like protein 0.0131 0.043 0.0735
Leishmania major calpain protease-like protein 0.0238 0.0839 0.1437
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0008 0.0006
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2632 1 1
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0305 0.0304
Leishmania major cathepsin L-like protease 0.0858 0.3214 0.5517
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0091 0.0143
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0187 0.0643 0.1996
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0063 0.0192
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Schistosoma mansoni cathepsin S (C01 family) 0.0219 0.0768 0.0766
Trypanosoma cruzi cysteine protease, putative 0.0478 0.176 0.1758
Loa Loa (eye worm) hypothetical protein 0.0068 0.0188 0.0188
Schistosoma mansoni hypothetical protein 0.0055 0.0141 0.0139
Echinococcus granulosus histone deacetylase 6 0.0098 0.0305 0.0304
Trypanosoma brucei kinesin, putative 0.0572 0.2117 0.3633
Toxoplasma gondii kringle domain-containing protein 0.0044 0.0099 0.0167
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0238 0.0839 0.2311
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Echinococcus multilocularis acylamino acid releasing enzyme 0.0187 0.0643 0.0641
Echinococcus granulosus dnaJ subfamily B 0.0413 0.1511 0.1509
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0068 0.019 0.0188
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0042 0.0091 0.0089
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0039 0.0039
Onchocerca volvulus 0.0599 0.2222 0.3807
Toxoplasma gondii calcium-dependent protein kinase 0.0133 0.0439 0.075
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0026 0.0076
Giardia lamblia Cathepsin L precursor 0.0219 0.0768 0.2116
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0219 0.0768 0.0768
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0238 0.0839 0.1437
Entamoeba histolytica grainin 2 0.0134 0.0443 0.1374
Loa Loa (eye worm) hypothetical protein 0.0061 0.0163 0.0163
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0273 0.0271
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.002 0.0019
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0042 0.0091 0.0153
Entamoeba histolytica cysteine protease, putative 0.0219 0.0768 0.2386
Brugia malayi Histone deacetylase family protein 0.0098 0.0305 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0219 0.0768 0.2116
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0063 0.0062
Echinococcus multilocularis histone deacetylase 3 0.0088 0.0264 0.0262
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0129 0.0423 0.0422
Echinococcus granulosus tumor protein p63 0.0358 0.1297 0.1296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0858 0.3214 0.887
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0259 0.0921 0.0921
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0219 0.0768 0.0766
Loa Loa (eye worm) hypothetical protein 0.0858 0.3214 0.3214
Plasmodium vivax histone deacetylase, putative 0.0098 0.0305 0.0945
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0126 0.0125
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0063 0.0121
Loa Loa (eye worm) calpain D 0.0238 0.0839 0.0839
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0084 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0478 0.176 0.3019
Trichomonas vaginalis calcineurin B subunit, putative 0.0131 0.043 0.1182
Schistosoma mansoni hypothetical protein 0.0061 0.0163 0.0161
Brugia malayi hypothetical protein 0.0064 0.0174 0.0172
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Schistosoma mansoni cathepsin B (C01 family) 0.0219 0.0768 0.0766
Entamoeba histolytica cysteine protease, putative 0.0858 0.3214 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Trichomonas vaginalis hypothetical protein 0.0238 0.0839 0.2311
Brugia malayi cathepsin Z-like cysteine proteinase 0.0219 0.0768 0.0766
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0068 0.019 0.0188
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0011 0.0009
Giardia lamblia Alanyl dipeptidyl peptidase 0.0187 0.0643 0.1771
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0174 0.0286
Giardia lamblia Cathepsin B precursor 0.0219 0.0768 0.2116
Trichomonas vaginalis chromobox protein, putative 0.007 0.0197 0.054
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0063 0.0121
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0011 0.0009
Toxoplasma gondii subtilisin SUB12 0.0029 0.0039 0.0064
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0091 0.0089
Schistosoma mansoni neuronal calcium sensor 0.0131 0.043 0.0428
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0163 0.0161
Brugia malayi Calmodulin-like protein 0.0131 0.043 0.0428
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0141 0.0139
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Onchocerca volvulus 0.0044 0.0099 0.0157
Loa Loa (eye worm) hypothetical protein 0.0055 0.0141 0.0141
Trypanosoma cruzi calpain cysteine peptidase, putative 0.081 0.3027 0.3026
Trypanosoma brucei calpain, putative 0.0238 0.0839 0.1437
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0008 0.0016
Leishmania major cathepsin L-like protease 0.0958 0.3595 0.6171
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0219 0.0768 0.0766
Schistosoma mansoni calmodulin 0.0131 0.043 0.0428
Echinococcus granulosus prolyl endopeptidase 0.1541 0.5825 0.5824
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0084 0.0228
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0511 0.1884 0.1883
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Entamoeba histolytica cysteine protease, putative 0.0478 0.176 0.5473
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0011 0.0011
Brugia malayi Cytochrome P450 family protein 0.0034 0.0057 0.0056
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0121 0.0121
Loa Loa (eye worm) proteasome subunit beta type 2 0.0042 0.0091 0.0091
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0046 0.0106 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0174 0.0173
Echinococcus multilocularis cathepsin L 0.0219 0.0768 0.0766
Loa Loa (eye worm) hypothetical protein 0.0064 0.0174 0.0174
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0084 0.0083
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0629 0.2338 0.4573
Schistosoma mansoni survival motor neuron protein 0.0052 0.0126 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0478 0.176 0.3019
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0858 0.3214 1
Loa Loa (eye worm) prolyl oligopeptidase 0.0511 0.1884 0.1884
Schistosoma mansoni histone deacetylase 0.0088 0.0264 0.0262
Loa Loa (eye worm) hypothetical protein 0.2632 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0079 0.0214
Loa Loa (eye worm) hypothetical protein 0.0131 0.043 0.043
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0011 0.0009
Brugia malayi PAN domain containing protein 0.0029 0.0039 0.0037
Entamoeba histolytica hypothetical protein 0.0041 0.0084 0.0257
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0063 0.0121

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) > 6.25 uM Concentration required for 50% cytotoxicity against human rhabdomyosarcoma cell lines ChEMBL. 15380197
CC50 (functional) > 6.25 uM Concentration required for 50% cytotoxicity against human rhabdomyosarcoma cell lines ChEMBL. 15380197
IC50 (functional) = 0.02 uM inhibition concentration required against human enterovirus 71 strain 4643 was determined by plaque reduction assay ChEMBL. 15380197

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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