Detailed information for compound 328283

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 980.145 | Formula: C47H65NO17S2
  • H donors: 4 H acceptors: 9 LogP: 3.61 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: CSSCCC(=O)O[C@H]1C(=O)[C@]2(C)C(O)C[C@@H]3[C@](C2[C@@H]([C@]2(C(C1=C(C)[C@@H](OC(=O)[C@@H]([C@@H](NC(=O)OC(C)(C)C)C=C(C)C)O)C2)(C)C)O)OC(=O)c1cc(OC)ccc1OC)(CO3)OC(=O)C
  • InChi: 1S/C47H65NO17S2/c1-23(2)18-28(48-42(56)65-43(5,6)7)35(52)41(55)61-30-21-47(57)39(63-40(54)27-19-26(58-11)14-15-29(27)59-12)37-45(10,31(50)20-32-46(37,22-60-32)64-25(4)49)38(53)36(34(24(30)3)44(47,8)9)62-33(51)16-17-67-66-13/h14-15,18-19,28,30-32,35-37,39,50,52,57H,16-17,20-22H2,1-13H3,(H,48,56)/t28-,30-,31?,32+,35+,36+,37?,39-,45+,46-,47+/m0/s1
  • InChiKey: PQNIQMKEJLHFNU-JGBQFYFCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2159 0.8709 0.8708
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0199 0.0717 0.2347
Onchocerca volvulus 0.0768 0.3036 0.4423
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0048 0.0102 0.0102
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0199 0.0717 0.2347
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0096 0.0295 0.0295
Brugia malayi eukaryotic initiation factor 4A 0.0025 0.0006 0.0006
Echinococcus multilocularis expressed protein 0.0809 0.3203 0.3199
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0341 0.1295 0.1881
Plasmodium falciparum proteasome subunit beta type-5 0.0088 0.0264 0.085
Loa Loa (eye worm) hypothetical protein 0.0145 0.0496 0.0496
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0199 0.0717 0.1985
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0268
Echinococcus multilocularis calumenin 0.0124 0.0412 0.0407
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0026 0.0028
Plasmodium falciparum serine repeat antigen 8 0.0199 0.0717 0.2347
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0439 0.0433
Trypanosoma cruzi kinesin, putative 0.0539 0.2105 0.21
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Echinococcus multilocularis prolyl endopeptidase 0.1704 0.6856 0.6854
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0068 0.0184 0.0178
Trichomonas vaginalis calmodulin, putative 0.0122 0.0404 0.111
Echinococcus granulosus calpain 0.0763 0.3018 0.3014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0042 0.0078 0.0105
Brugia malayi calpain 5 0.0224 0.0818 0.0818
Loa Loa (eye worm) calpain D 0.0224 0.0818 0.0818
Plasmodium falciparum serine repeat antigen 4 0.0199 0.0717 0.2347
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0404 0.111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.029 0.029
Toxoplasma gondii centrin, putative 0.0122 0.0404 0.0581
Loa Loa (eye worm) hypothetical protein 0.0122 0.0404 0.0403
Leishmania major centrin, putative,caltractin, putative 0.0122 0.0404 0.0581
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.0818 0.0813
Trypanosoma cruzi major cysteine proteinase, putative 0.0301 0.1133 0.1127
Trichomonas vaginalis calmodulin, putative 0.0126 0.0418 0.115
Trypanosoma cruzi I/6 autoantigen, putative 0.0122 0.0404 0.0398
Echinococcus granulosus sodium and chloride dependent glycine 0.0089 0.0268 0.0262
Brugia malayi cathepsin F-like cysteine proteinase 0.0199 0.0717 0.0717
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0061 0.0055
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0768 0.3036 0.8459
Plasmodium falciparum cysteine proteinase falcipain 1 0.043 0.1657 0.545
Plasmodium vivax proteasome subunit beta type-5, putative 0.0088 0.0264 0.085
Toxoplasma gondii hypothetical protein 0.0029 0.0026 0.0028
Plasmodium vivax proteasome subunit beta type-2, putative 0.0042 0.0078 0.0237
Brugia malayi Trypsin family protein 0.0145 0.0496 0.0496
Schistosoma mansoni cpg binding protein 0.0032 0.0036 0.0036
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Schistosoma mansoni hypothetical protein 0.0122 0.0404 0.0404
Loa Loa (eye worm) prolyl oligopeptidase 0.0537 0.2094 0.2094
Brugia malayi calcium-binding protein 0.0122 0.0404 0.0403
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0124 0.0412 0.0412
Entamoeba histolytica hypothetical protein 0.0199 0.0717 0.2347
Entamoeba histolytica cysteine protease, putative 0.0199 0.0717 0.2347
Schistosoma mansoni inhibitor of apoptosis protein 0.018 0.0638 0.0638
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0199 0.0717 0.0717
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0285 0.0285
Giardia lamblia Encystation-specific protease 0.0199 0.0717 0.1985
Schistosoma mansoni hypothetical protein 0.0433 0.1671 0.1671
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0075 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0537 0.2096 0.5834
Plasmodium falciparum serine repeat antigen 7 0.0199 0.0717 0.2347
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.1813 0.7298 0.7297
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0199 0.0717 0.1985
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.043 0.1657 0.2411
Onchocerca volvulus 0.0029 0.0026 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.043 0.1657 0.461
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0075 0.0074
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0768 0.3036 0.3032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Echinococcus multilocularis endothelin converting enzyme 1 0.0096 0.0295 0.0289
Leishmania major programmed cell death 6 protein-like protein 0.0122 0.0404 0.0581
Echinococcus granulosus cathepsin L cysteine proteinase 0.0768 0.3036 0.3032
Trypanosoma brucei caltractin, putative 0.0126 0.0418 0.0601
Schistosoma mansoni ap endonuclease 0.0038 0.0061 0.0061
Onchocerca volvulus 0.0064 0.0167 0.0235
Echinococcus granulosus cathepsin b 0.2475 1 1
Onchocerca volvulus 0.0064 0.0167 0.0235
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0903 0.3588 0.5229
Entamoeba histolytica hypothetical protein, conserved 0.0204 0.0739 0.2418
Leishmania major calpain family cysteine protease-like protein 0.0224 0.0818 0.1186
Echinococcus multilocularis centrin 2 0.0122 0.0404 0.0398
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Plasmodium falciparum peptidase, putative 0.0204 0.0739 0.2418
Brugia malayi Cathepsin L-like precursor 0.0768 0.3036 0.3036
Schistosoma mansoni gamma-secretase subunit aph-1 0.0249 0.0923 0.0923
Schistosoma mansoni ef hand domain family member A2 0.0122 0.0404 0.0404
Trichomonas vaginalis calpain, putative 0.0224 0.0818 0.2267
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0061 0.0055
Onchocerca volvulus 0.0145 0.0496 0.0716
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Toxoplasma gondii subtilisin SUB12 0.0029 0.0026 0.0028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0026 0.0028
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0026 0.0028
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0052 0.0076
Loa Loa (eye worm) hypothetical protein 0.0042 0.0075 0.0074
Schistosoma mansoni neuronal calcium sensor 0.0122 0.0404 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0199 0.0717 0.1985
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0061 0.0058
Leishmania major calmodulin, putative 0.0122 0.0404 0.0581
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Leishmania major cathepsin L-like protease 0.0768 0.3036 0.4423
Loa Loa (eye worm) hypothetical protein 0.0145 0.0496 0.0496
Onchocerca volvulus 0.0145 0.0496 0.0716
Trypanosoma cruzi caltractin, putative 0.0122 0.0404 0.0398
Plasmodium falciparum flap endonuclease 1 0.0026 0.001 0.0013
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0344 0.1115
Brugia malayi Papain family cysteine protease containing protein 0.043 0.1657 0.1657
Plasmodium vivax unspecified product 0.043 0.1657 0.545
Entamoeba histolytica cysteine protease, putative 0.0199 0.0717 0.2347
Leishmania major cathepsin L-like protease 0.087 0.3452 0.503
Echinococcus granulosus cathepsin l1 0.0768 0.3036 0.3032
Onchocerca volvulus 0.0768 0.3036 0.4423
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0496
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0071 0.0194 0.0193
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0639 0.2512 0.2507
Onchocerca volvulus 0.0164 0.0573 0.0827
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0089 0.0268 0.0268
Entamoeba histolytica cysteine proteinase, putative 0.0768 0.3036 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Entamoeba histolytica hypothetical protein, conserved 0.0124 0.0412 0.1341
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0285 0.0285
Echinococcus granulosus survival motor neuron protein 1 0.0253 0.0938 0.0932
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0199 0.0717 0.1985
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0204 0.0739 0.2045
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0199 0.0717 0.0717
Giardia lamblia Hypothetical protein 0.0199 0.0717 0.1985
Trypanosoma cruzi centrin-3 0.0126 0.0418 0.0412
Leishmania major i/6 autoantigen-like protein 0.0122 0.0404 0.0581
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0075 0.0075
Trypanosoma brucei calpain-like protein, putative 0.0763 0.3018 0.4397
Loa Loa (eye worm) calpain family protein 1 0.2036 0.821 0.821
Leishmania major calcineurin B subunit, putative 0.0122 0.0404 0.0581
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0768 0.3036 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0078 0.02
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Trypanosoma brucei metacaspase MCA2 0.0341 0.1295 0.1881
Onchocerca volvulus Cathepsin L homolog 0.0768 0.3036 0.4423
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0075 0.0069
Trypanosoma brucei cysteine peptidase, putative 0.0224 0.0818 0.1186
Schistosoma mansoni calpain (C02 family) 0.0763 0.3018 0.3018
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0075 0.0074
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0052 0.0025
Treponema pallidum sodium- and chloride- dependent transporter 0.0524 0.2041 1
Onchocerca volvulus 0.0089 0.0268 0.0382
Onchocerca volvulus 0.0524 0.2041 0.2971
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.029 0.0284
Trypanosoma cruzi centrin, putative 0.0126 0.0418 0.0412
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1295 0.3598
Loa Loa (eye worm) hypothetical protein 0.0255 0.0947 0.0947
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0075 0.0074
Brugia malayi prolyl oligopeptidase family protein 0.0297 0.1117 0.1117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.029 0.029
Echinococcus granulosus cathepsin L 0.043 0.1657 0.1652
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Trypanosoma cruzi cysteine peptidase, putative 0.0231 0.0846 0.084
Leishmania major calmodulin-like protein 0.0122 0.0404 0.0581
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0537 0.2094 0.2094
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0268
Brugia malayi cathepsin Z-like cysteine proteinase 0.0199 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0052 0.0116 0.0116
Entamoeba histolytica cysteine proteinase 1, putative 0.043 0.1657 0.545
Loa Loa (eye worm) hypothetical protein 0.0231 0.0846 0.0845
Echinococcus granulosus caspase 3 0.0506 0.1969 0.1964
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0045 0.0045
Trypanosoma brucei calpain, putative 0.0224 0.0818 0.1186
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Onchocerca volvulus 0.0122 0.0404 0.0581
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.4397
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0199 0.0717 0.2347
Schistosoma mansoni calmodulin 0.0122 0.0404 0.0404
Loa Loa (eye worm) ctsf protein 0.0768 0.3036 0.3036
Brugia malayi fibroinase precursor 0.0199 0.0717 0.0717
Mycobacterium ulcerans hypothetical protein 0.0211 0.0767 0.2679
Brugia malayi cathepsin L precursor 0.0199 0.0717 0.0717
Trypanosoma cruzi metacaspase, putative 0.0341 0.1295 0.129
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0068 0.0184 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Entamoeba histolytica calcium-binding protein, putative 0.0122 0.0404 0.1312
Onchocerca volvulus 0.0029 0.0026 0.0028
Trypanosoma brucei Calpain-like protein 2 0.0224 0.0818 0.1186
Giardia lamblia Cathepsin L precursor 0.0199 0.0717 0.1985
Schistosoma mansoni cathepsin F (C01 family) 0.0768 0.3036 0.3036
Entamoeba histolytica calmodulin, putative 0.0122 0.0404 0.1312
Onchocerca volvulus 0.0046 0.0091 0.0124
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0075 0.0069
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0231 0.0846 0.0845
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0061 0.006
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0075 0.0069
Trypanosoma brucei metacaspase MCA3 0.0341 0.1295 0.1881
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0075 0.0075
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0199 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0122 0.0404 0.0403
Echinococcus granulosus glycoprotein Antigen 5 0.0145 0.0496 0.0491
Trypanosoma cruzi oligopeptidase b 0.0695 0.274 0.2735
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0075 0.0192
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0145 0.0496 0.0491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Echinococcus multilocularis calcium uptake protein 1 0.0124 0.0412 0.0407
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1295 0.3598
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0341 0.1295 0.1881
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0273 0.0267
Brugia malayi Flap endonuclease-1 0.0026 0.001 0.001
Loa Loa (eye worm) cysteine protease 0.0768 0.3036 0.3036
Trypanosoma cruzi oligopeptidase b 0.0695 0.274 0.2735
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0025
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0089 0.0268 0.0262
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0052 0.0052
Leishmania major proteasome beta 5 subunit, putative 0.0088 0.0264 0.0376
Loa Loa (eye worm) hypothetical protein 0.0204 0.0739 0.0738
Schistosoma mansoni centrin-related 0.0122 0.0404 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1295 0.3598
Leishmania major metacaspase, putative 0.0341 0.1295 0.1881
Echinococcus multilocularis survival motor neuron protein 1 0.0253 0.0938 0.0932
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0167 0.0166
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0199 0.0717 0.1985
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0089 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0204 0.0739 0.0738
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0088 0.0264 0.0719
Brugia malayi prolyl oligopeptidase family protein 0.0537 0.2094 0.2094
Brugia malayi PXA domain containing protein 0.0042 0.0075 0.0074
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0167 0.0166
Onchocerca volvulus 0.0744 0.2941 0.4285
Echinococcus multilocularis neurocalcin 0.0122 0.0404 0.0398
Schistosoma mansoni hypothetical protein 0.0122 0.0404 0.0404
Echinococcus granulosus cpg binding protein 0.0032 0.0036 0.003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.029 0.0284
Loa Loa (eye worm) hypothetical protein 0.0199 0.0717 0.0717
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2475 1 1
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.018 0.0638 0.0637
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0061 0.0091
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0763 0.3018 0.4397
Giardia lamblia Glycogen phosphorylase 0.0108 0.0344 0.0943
Mycobacterium ulcerans lipase LipD 0.0036 0.0052 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Entamoeba histolytica cysteine protease, putative 0.0199 0.0717 0.2347
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0091 0.0085
Schistosoma mansoni calpain-7 (C02 family) 0.0766 0.303 0.303
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Schistosoma mansoni cathepsin C 0.0199 0.0717 0.0717
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0344 0.1115
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0167 0.0166
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0026 0.0025
Echinococcus multilocularis calbindin 32 0.0124 0.0412 0.0407
Chlamydia trachomatis glycogen phosphorylase 0.0108 0.0344 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0268
Trypanosoma cruzi metacaspase 5, putative 0.0341 0.1295 0.129
Echinococcus granulosus EF hand domain containing family member A2 0.0124 0.0412 0.0407
Plasmodium vivax amine transporter, putative 0.0089 0.0268 0.0864
Trypanosoma brucei calpain-like protein, putative 0.0763 0.3018 0.4397
Echinococcus granulosus expressed protein 0.0809 0.3203 0.3199
Brugia malayi EF hand family protein 0.0124 0.0412 0.0412
Schistosoma mansoni cathepsin S (C01 family) 0.0199 0.0717 0.0717
Trichomonas vaginalis calmodulin, putative 0.0122 0.0404 0.111
Loa Loa (eye worm) hypothetical protein 0.0231 0.0846 0.0845
Onchocerca volvulus 0.0124 0.0412 0.0593
Trypanosoma cruzi conserved protein 0.0224 0.0818 0.0813
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0052 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0075 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0075 0.0075
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0089 0.0268 0.0268
Onchocerca volvulus 0.0029 0.0026 0.0028
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0268
Trichomonas vaginalis calmodulin, putative 0.0122 0.0404 0.111
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0199 0.0717 0.1985
Echinococcus multilocularis cysteine protease 0.0768 0.3036 0.3032
Trichomonas vaginalis calcineurin B subunit, putative 0.0122 0.0404 0.111
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0167 0.0166
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0224 0.0818 0.0813
Leishmania major phospholipase c-like protein 0.0122 0.0404 0.0581
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0122 0.0404 0.0581
Loa Loa (eye worm) hypothetical protein 0.0199 0.0717 0.0717
Trypanosoma cruzi prolyl endopeptidase 0.1704 0.6856 0.6854
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.0818 0.0813
Schistosoma mansoni peroxidasin 0.0064 0.0167 0.0167
Schistosoma mansoni neuronal calcium sensor 0.0122 0.0404 0.0404
Entamoeba histolytica protein kinase, putative 0.0539 0.2105 0.6927
Trichomonas vaginalis calmodulin, putative 0.0122 0.0404 0.111
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2475 1 1
Schistosoma mansoni neuronal calcium sensor 0.0122 0.0404 0.0404
Echinococcus multilocularis serotonin transporter 0.0524 0.2041 0.2036
Leishmania major cathepsin L-like protease 0.087 0.3452 0.503
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0052
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0903 0.3588 0.3588
Mycobacterium tuberculosis Conserved protein 0.0036 0.0052 0.0076
Leishmania major calmodulin, putative 0.0122 0.0404 0.0581
Trypanosoma brucei metacaspase 5, putative 0.0341 0.1295 0.1881
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0026 0.0028
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0249 0.0923 0.0922
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0122 0.0404 0.111
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.001 0.0013
Echinococcus granulosus Glycosyl transferase family 35 0.0108 0.0344 0.0338
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0439 0.146
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0122 0.0404 0.0398
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0199 0.0717 0.0717
Leishmania major cathepsin L-like protease 0.0768 0.3036 0.4423
Echinococcus granulosus cathepsin L cysteine protease 0.043 0.1657 0.1652
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0042 0.0078 0.0237
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Echinococcus granulosus cathepsin l1 0.0537 0.2096 0.2091
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0344 0.0338
Plasmodium falciparum serine repeat antigen 2 0.0199 0.0717 0.2347
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0297 0.1117 0.1117
Onchocerca volvulus Deterin homolog 0.018 0.0638 0.0922
Onchocerca volvulus 0.0094 0.029 0.0415
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0199 0.0717 0.1985
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0052 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.043 0.1657 0.461
Brugia malayi Papain family cysteine protease containing protein 0.0768 0.3036 0.3036
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0075 0.0069
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0224 0.0818 0.2267
Trypanosoma cruzi cysteine peptidase, putative 0.087 0.3452 0.3448
Plasmodium vivax calpain, putative 0.0763 0.3018 0.994
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0098
Toxoplasma gondii hypothetical protein 0.0089 0.0268 0.0382
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.4397
Giardia lamblia Cathepsin L precursor 0.0199 0.0717 0.1985
Loa Loa (eye worm) hypothetical protein 0.0231 0.0846 0.0845
Trypanosoma cruzi 20S proteasome subunit 0.0042 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0052
Echinococcus granulosus calbindin 32 0.0124 0.0412 0.0407
Giardia lamblia Cathepsin B precursor 0.0903 0.3588 1
Loa Loa (eye worm) beta-lactamase 0.0036 0.0052 0.0052
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.043 0.1657 0.1657
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0199 0.0717 0.1985
Trypanosoma brucei calmodulin, putative 0.0124 0.0412 0.0593
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Brugia malayi Papain family cysteine protease containing protein 0.0199 0.0717 0.0717
Loa Loa (eye worm) calmodulin-like protein 0.0122 0.0404 0.0403
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0224 0.0818 0.2267
Entamoeba histolytica cysteine proteinase, putative 0.0537 0.2096 0.6897
Onchocerca volvulus 0.0029 0.0026 0.0028
Echinococcus multilocularis caspase 0.0847 0.3359 0.3355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Trypanosoma brucei calmodulin, putative 0.0122 0.0404 0.0581
Mycobacterium tuberculosis Probable peptidase 0.0695 0.274 0.4544
Trypanosoma brucei Aph-1 protein, putative 0.0097 0.0302 0.0431
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Trichomonas vaginalis calcium binding protein, putative 0.0122 0.0404 0.111
Trypanosoma brucei calpain-like protein, putative 0.0763 0.3018 0.4397
Echinococcus granulosus cathepsin L 0.0199 0.0717 0.0712
Trypanosoma cruzi cysteine proteinase, putative 0.043 0.1657 0.1652
Loa Loa (eye worm) calpain 0.0763 0.3018 0.3018
Loa Loa (eye worm) hypothetical protein 0.0072 0.02 0.02
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0026 0.0028
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0654 0.2572 0.2572
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0344 0.0943
Loa Loa (eye worm) hypothetical protein 0.0199 0.0717 0.0717
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0391 0.0391
Giardia lamblia Cathepsin B precursor 0.0199 0.0717 0.1985
Echinococcus granulosus gamma secretase subunit aph 1 0.0249 0.0923 0.0917
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0695 0.274 1
Trichomonas vaginalis calmodulin, putative 0.0124 0.0412 0.1134
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0524 0.2041 0.2041
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Trypanosoma cruzi calmodulin, putative 0.0122 0.0404 0.0398
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0061 0.0181
Loa Loa (eye worm) hypothetical protein 0.0096 0.0295 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0199 0.0717 0.1985
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0061 0.0153
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0268
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0045 0.0039
Brugia malayi Cathepsin L-like precursor 0.0537 0.2096 0.2096
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0052 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Mycobacterium ulcerans zinc metalloprotease 0.0096 0.0295 0.0927
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0089 0.0268 0.0262
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0763 0.3018 0.3014
Echinococcus granulosus Mastin 0.0145 0.0496 0.0491
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Schistosoma mansoni hypothetical protein 0.018 0.0638 0.0638
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0199 0.0717 0.2347
Plasmodium vivax proteasome subunit beta type-1, putative 0.0068 0.0184 0.0586
Leishmania major hypothetical protein, conserved 0.0036 0.0052 0.0067
Brugia malayi hypothetical protein 0.0145 0.0496 0.0496
Plasmodium falciparum metacaspase 1 0.0341 0.1295 0.4253
Loa Loa (eye worm) hypothetical protein 0.0145 0.0496 0.0496
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0496
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0439 0.0439
Onchocerca volvulus 0.0029 0.0026 0.0028
Brugia malayi CXXC zinc finger family protein 0.003 0.0029 0.0029
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0068 0.0184 0.0178
Toxoplasma gondii exonuclease III APE 0.0038 0.0061 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.4397
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0297 0.1117 0.1622
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0204 0.0739 0.2045
Echinococcus granulosus calpain A 0.2161 0.8718 0.8717
Loa Loa (eye worm) cathepsin B 0.0903 0.3588 0.3588
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0285 0.0279
Loa Loa (eye worm) hypothetical protein 0.1497 0.6011 0.6011
Brugia malayi Peroxidasin 0.0064 0.0167 0.0166
Mycobacterium tuberculosis Conserved protein 0.0036 0.0052 0.0076
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Entamoeba histolytica prolyl oligopeptidase family protein 0.0204 0.0739 0.2418
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0199 0.0717 0.2347
Trypanosoma brucei oligopeptidase b 0.0695 0.274 0.3991
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0297 0.1117 0.1112
Brugia malayi beta-lactamase family protein 0.0036 0.0052 0.0052
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Echinococcus multilocularis cathepsin b 0.2475 1 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0154 0.0216
Echinococcus granulosus prolyl endopeptidase 0.1704 0.6856 0.6854
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0122 0.0404 0.0398
Trichomonas vaginalis calcium binding proteins, putative 0.0122 0.0404 0.111
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0052 0.0076
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0052 0.0151
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0091 0.0091
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0089 0.0268 0.0268
Trypanosoma cruzi calmodulin, putative 0.0122 0.0404 0.0398
Trypanosoma brucei calpain, putative 0.0224 0.0818 0.1186
Giardia lamblia Cathepsin L-like protease 0.0199 0.0717 0.1985
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0061 0.0055
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0045 0.0045
Loa Loa (eye worm) proteasome subunit beta type 1 0.0068 0.0184 0.0183
Plasmodium vivax centrin-1, putative 0.0122 0.0404 0.1312
Echinococcus multilocularis gamma secretase subunit aph 1 0.0249 0.0923 0.0917
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0204 0.0739 0.0739
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0439 0.0719
Echinococcus granulosus transmembrane protease serine 3 0.0145 0.0496 0.0491
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0071 0.0194 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Onchocerca volvulus 0.0089 0.0268 0.0382
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.15 0.6023 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0199 0.0717 0.1985
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0768 0.3036 0.3036
Entamoeba histolytica Flap nuclease, putative 0.0026 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0199 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0199 0.0717 0.0717
Giardia lamblia Cathepsin B precursor 0.0199 0.0717 0.1985
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.3014
Echinococcus multilocularis tissue type plasminogen activator 0.0046 0.0091 0.0085
Toxoplasma gondii microneme protein, putative 0.0029 0.0026 0.0028
Schistosoma mansoni sodium/chloride dependent transporter 0.0089 0.0268 0.0268
Brugia malayi Trypsin-like protease protein 5 0.0145 0.0496 0.0496
Toxoplasma gondii calmodulin CAM1 0.0124 0.0412 0.0593
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.0818 0.0813
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0264 0.0258
Schistosoma mansoni hypothetical protein 0.0145 0.0496 0.0496
Entamoeba histolytica cysteine protease, putative 0.0768 0.3036 1
Echinococcus granulosus acylamino acid releasing enzyme 0.0204 0.0739 0.0733
Echinococcus multilocularis calpain A 0.2161 0.8718 0.8717
Echinococcus multilocularis Glycosyl transferase, family 35 0.0108 0.0344 0.0338
Loa Loa (eye worm) hypothetical protein 0.0596 0.2337 0.2337
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0075 0.0075
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0199 0.0717 0.0717
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0768 0.3036 0.3032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0439 0.146
Echinococcus multilocularis cathepsin L cysteine protease 0.0768 0.3036 0.3032
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.0818 0.0813
Trichomonas vaginalis calcineurin B subunit, putative 0.0124 0.0412 0.1134
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0199 0.0717 0.1985
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0145 0.0496 0.0491
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0122 0.0404 0.111
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0088 0.0264 0.0376
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0382
Echinococcus multilocularis caspase 8 0.0341 0.1295 0.129
Loa Loa (eye worm) calpain family protein 1 0.1497 0.6011 0.6011
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0075 0.0075
Echinococcus multilocularis EF hand domain containing family member A2 0.0122 0.0404 0.0398
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.0006 0.0006
Leishmania major cathepsin L-like protease 0.0768 0.3036 0.4423
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0344 0.0344
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0042 0.0078 0.0105
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0095 0.0293
Entamoeba histolytica cysteine protease, putative 0.0199 0.0717 0.2347
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0344 0.0338
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0224 0.0818 0.0813
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1704 0.6856 0.6856
Brugia malayi prolyl oligopeptidase family protein 0.0204 0.0739 0.0738
Schistosoma mansoni caspase-7 (C14 family) 0.0596 0.2337 0.2337
Onchocerca volvulus 0.0145 0.0496 0.0716
Schistosoma mansoni calpain-7 (C02 family) 0.0766 0.303 0.303
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Plasmodium falciparum serine repeat antigen 5 0.0199 0.0717 0.2347
Brugia malayi beta-lactamase 0.0036 0.0052 0.0052
Echinococcus multilocularis cathepsin b 0.2475 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0052 0.0128
Echinococcus granulosus calpain 7 C02 family 0.0763 0.3018 0.3014
Echinococcus multilocularis cysteine protease 0.0768 0.3036 0.3032
Echinococcus multilocularis calmodulin 0.0122 0.0404 0.0398
Echinococcus multilocularis transmembrane protease serine 3 0.0145 0.0496 0.0491
Plasmodium vivax hypothetical protein, conserved 0.0089 0.0268 0.0864
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0088 0.0264 0.0719
Toxoplasma gondii centrin 0.0122 0.0404 0.0581
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0199 0.0717 0.0717
Onchocerca volvulus 0.0036 0.0052 0.0067
Loa Loa (eye worm) trypsin family protein 0.0145 0.0496 0.0496
Trypanosoma brucei metacaspase 0.0341 0.1295 0.1881
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0122 0.0404 0.1312
Plasmodium vivax serine-repeat antigen (SERA) 0.0199 0.0717 0.2347
Entamoeba histolytica grainin, putative 0.0124 0.0412 0.1341
Brugia malayi Cathepsin L-like precursor 0.0768 0.3036 0.3036
Mycobacterium tuberculosis Conserved hypothetical protein 0.0211 0.0767 0.1265
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0052 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0412 0.1341
Echinococcus granulosus microtubule associated protein 2 0.1495 0.6002 0.5999
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Toxoplasma gondii EF hand domain-containing protein 0.0122 0.0404 0.0581
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0763 0.3018 0.3014
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0075 0.0069
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0095 0.0293
Leishmania major cathepsin L-like protease 0.0768 0.3036 0.4423
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0285 0.0279
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0075 0.0069
Loa Loa (eye worm) hypothetical protein 0.0164 0.0573 0.0573
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0095 0.0095
Toxoplasma gondii hypothetical protein 0.0204 0.0739 0.107
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0199 0.0717 0.2347
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Trypanosoma cruzi calmodulin, putative 0.0122 0.0404 0.0398
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0052 0.0052
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0763 0.3018 0.3014
Leishmania major proteasome beta 2 subunit, putative 0.0042 0.0078 0.0105
Schistosoma mansoni neprilysin-2 (M13 family) 0.0048 0.0102 0.0102
Entamoeba histolytica hypothetical protein 0.0042 0.0075 0.0226
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0231 0.0846 0.0845
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0088 0.0264 0.0264
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0075 0.0075
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Brugia malayi proteasome subunit beta type 1 0.0068 0.0184 0.0183
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0122 0.0404 0.1312
Echinococcus multilocularis sodium and chloride dependent glycine 0.0089 0.0268 0.0262
Trypanosoma brucei Calpain-like protein CALP1.3 0.0224 0.0818 0.1186
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.001 0.0011
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0026 0.0028
Giardia lamblia Cathepsin B precursor 0.0903 0.3588 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0285 0.0284
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0045 0.0057
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0268
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0068 0.0184 0.0184
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0199 0.0717 0.2347
Leishmania major hypothetical protein, conserved 0.0122 0.0404 0.0581
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0088 0.0264 0.0788
Mycobacterium tuberculosis Conserved hypothetical protein 0.0211 0.0767 0.1265
Trypanosoma brucei centrin-3 0.0126 0.0418 0.0601
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0122 0.0404 0.0398
Brugia malayi cathepsin L-like cysteine proteinase 0.0199 0.0717 0.0717
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Echinococcus multilocularis hypothetical protein 0.0763 0.3018 0.3014
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0068 0.0184 0.0259
Entamoeba histolytica hypothetical protein 0.0042 0.0075 0.0226
Onchocerca volvulus 0.0029 0.0026 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0199 0.0717 0.1985
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0095 0.0148
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Echinococcus granulosus caspase 8 0.0341 0.1295 0.129
Giardia lamblia Cathepsin B precursor 0.0903 0.3588 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0268
Plasmodium vivax serine-repeat antigen (SERA) 0.0199 0.0717 0.2347
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0052 0.0128
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0075 0.0069
Loa Loa (eye worm) hypothetical protein 0.0145 0.0496 0.0496
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0061 0.0181
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0089 0.0268 0.0268
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Trichomonas vaginalis calcium binding protein, putative 0.0126 0.0418 0.115
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0167 0.0235
Brugia malayi Cathepsin L-like precursor 0.0768 0.3036 0.3036
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0695 0.274 0.3991
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0439 0.146
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0052
Brugia malayi calpain family protein 1 0.2036 0.821 0.821
Loa Loa (eye worm) fibroinase 0.0768 0.3036 0.3036
Mycobacterium ulcerans putative transglutaminase-like protein 0.0211 0.0767 0.2679
Echinococcus granulosus Dipeptidyl peptidase 9 0.0297 0.1117 0.1112
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0075 0.0069
Echinococcus multilocularis calpain 5 0.0763 0.3018 0.3014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0763 0.3018 0.3014
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Schistosoma mansoni ap endonuclease 0.0038 0.0061 0.0061
Plasmodium falciparum serine repeat antigen 6 0.0199 0.0717 0.2347
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0224 0.0818 0.0813
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0088 0.0264 0.0263
Plasmodium vivax unspecified product 0.0199 0.0717 0.2347
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Brugia malayi Trypsin family protein 0.0145 0.0496 0.0496
Echinococcus granulosus calmodulin 0.0122 0.0404 0.0398
Echinococcus granulosus calpain 5 0.0763 0.3018 0.3014
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0537 0.2094 0.2089
Brugia malayi Calmodulin-like protein 0.0122 0.0404 0.0403
Echinococcus multilocularis glycoprotein Antigen 5 0.0145 0.0496 0.0491
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Trichomonas vaginalis set domain proteins, putative 0.0744 0.294 0.8191
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0061 0.0055
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.3014
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0078 0.02
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0224 0.0818 0.1186
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2475 1 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0382
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0199 0.0717 0.2347
Loa Loa (eye worm) hypothetical protein 0.0094 0.029 0.029
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0297 0.1117 0.1112
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0391 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0075 0.0192
Entamoeba histolytica calmodulin, putative 0.0122 0.0404 0.1312
Toxoplasma gondii ABC1 family protein 0.0036 0.0052 0.0067
Loa Loa (eye worm) norepinephrine transporter 0.0524 0.2041 0.2041
Loa Loa (eye worm) hypothetical protein 0.018 0.0638 0.0637
Toxoplasma gondii hypothetical protein 0.0029 0.0026 0.0028
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0224 0.0818 0.0813
Loa Loa (eye worm) hypothetical protein 0.0072 0.02 0.02
Entamoeba histolytica prolyl oligopeptidase family protein 0.0204 0.0739 0.2418
Giardia lamblia Alanyl dipeptidyl peptidase 0.0204 0.0739 0.2045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0025
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0068 0.0184 0.0178
Schistosoma mansoni centrin 0.0122 0.0404 0.0404
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0768 0.3036 1
Brugia malayi Trypsin family protein 0.0145 0.0496 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.0199 0.0717 0.1985
Echinococcus granulosus apoptotic protease activating factor 1 0.0255 0.0947 0.0942
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0026 0.0025
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0089 0.0268 0.0262
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0061 0.008
Trypanosoma brucei Component of motile flagella 41 0.0122 0.0404 0.0581
Onchocerca volvulus 0.0199 0.0717 0.1038
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0061 0.0153
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0439 0.0439
Loa Loa (eye worm) hypothetical protein 0.0046 0.0091 0.0091
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0167 0.0166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1704 0.6856 0.6856
Brugia malayi Cathepsin L-like precursor 0.0768 0.3036 0.3036
Trypanosoma brucei proteasome beta 6 subunit 0.0068 0.0184 0.0259
Brugia malayi Cathepsin L-like precursor 0.0768 0.3036 0.3036
Echinococcus granulosus sodium and chloride dependent glycine 0.0089 0.0268 0.0262
Giardia lamblia Cysteine protease 0.0199 0.0717 0.1985
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Trypanosoma cruzi major cysteine proteinase, putative 0.0199 0.0717 0.0712
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0199 0.0717 0.0717
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0199 0.0717 0.0717
Trypanosoma cruzi cysteine peptidase, putative 0.087 0.3452 0.3448
Echinococcus multilocularis programmed cell death protein 0.0126 0.0418 0.0412
Loa Loa (eye worm) hypothetical protein 0.0072 0.02 0.02
Trypanosoma cruzi metacaspase, putative 0.0341 0.1295 0.129
Brugia malayi hypothetical protein 0.0042 0.0075 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0199 0.0717 0.1985
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0763 0.3018 0.3014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.029 0.0284
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0285 0.0279
Loa Loa (eye worm) hypothetical protein 0.0768 0.3036 0.3036
Plasmodium vivax unspecified product 0.0231 0.0846 0.277
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0404 0.111
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0264 0.0258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0297 0.1117 0.1622
Trypanosoma cruzi metacaspase, putative 0.0341 0.1295 0.129
Loa Loa (eye worm) EF hand family protein 0.0122 0.0404 0.0403
Onchocerca volvulus 0.0145 0.0496 0.0716
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.018 0.0638 0.0638
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0199 0.0717 0.2347
Schistosoma mansoni cathepsin F (C01 family) 0.0537 0.2096 0.2096
Trypanosoma brucei mitochondrial calcium uptake 1 0.0122 0.0404 0.0581
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0122 0.0404 0.0404
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0124 0.0124
Schistosoma mansoni calmodulin related calcium binding protein 0.0122 0.0404 0.0404
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0344 0.0344
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0042 0.0078 0.0237
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0026 0.0028
Leishmania major kinesin, putative 0.0539 0.2105 0.3064
Mycobacterium tuberculosis Conserved protein 0.0211 0.0767 0.1265
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0199 0.0717 0.2347
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0341 0.1295 0.1881
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0199 0.0717 0.1985
Leishmania major protein kinase, putative 0.0122 0.0404 0.0581
Schistosoma mansoni hypothetical protein 0.0145 0.0496 0.0496
Schistosoma mansoni mitochondrial solute carrier 0.0122 0.0404 0.0404
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0061 0.008
Loa Loa (eye worm) hypothetical protein 0.018 0.0638 0.0637
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.018 0.0638 0.0637
Brugia malayi gamma-secretase subunit aph-1 0.0249 0.0923 0.0922
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0061 0.5
Loa Loa (eye worm) serotonin transporter b 0.0524 0.2041 0.2041
Trypanosoma brucei I/6 autoantigen 0.0122 0.0404 0.0581
Brugia malayi Cytochrome P450 family protein 0.0034 0.0045 0.0045
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0052 0.0052
Giardia lamblia Cathepsin B precursor 0.0199 0.0717 0.1985
Echinococcus granulosus caspase 2 0.0596 0.2337 0.2332
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0199 0.0717 0.0717
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0145 0.0496 0.0496
Leishmania major cytochrome p450-like protein 0.0034 0.0045 0.0057
Leishmania major cathepsin L-like protease 0.0768 0.3036 0.4423
Brugia malayi calpain 7 0.0763 0.3018 0.3018
Echinococcus granulosus dnaJ subfamily B 0.0433 0.1671 0.1665
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0199 0.0717 0.1985
Giardia lamblia Cathepsin L precursor 0.0199 0.0717 0.1985
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0025
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0285 0.0284
Loa Loa (eye worm) glycogen phosphorylase 0.0108 0.0344 0.0344
Echinococcus multilocularis flap endonuclease 1 0.0026 0.001 0.0004
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0496
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0496
Entamoeba histolytica cysteine proteinase, putative 0.043 0.1657 0.545
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Trypanosoma cruzi kinesin, putative 0.0539 0.2105 0.21
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0026 0.0028
Onchocerca volvulus 0.0054 0.0124 0.0172
Onchocerca volvulus 0.0052 0.0116 0.016
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0491
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0391 0.1501 0.1496
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0199 0.0717 0.0717
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0088 0.0264 0.0428
Toxoplasma gondii peptidase family M13 protein 0.0096 0.0295 0.0422
Brugia malayi prolyl oligopeptidase family protein 0.1704 0.6856 0.6856
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0026 0.0025
Echinococcus granulosus Transglutaminase 0.0211 0.0767 0.0761
Trypanosoma cruzi metacaspase, putative 0.0341 0.1295 0.129
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0268
Giardia lamblia Hypothetical protein 0.0199 0.0717 0.1985
Trichomonas vaginalis calmodulin, putative 0.0122 0.0404 0.111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0199 0.0717 0.1985
Entamoeba histolytica cysteine proteinase, putative 0.043 0.1657 0.545
Trichomonas vaginalis calmodulin, putative 0.0122 0.0404 0.111
Entamoeba histolytica cysteine protease, putative 0.0199 0.0717 0.2347
Trypanosoma cruzi cysteine peptidase, putative 0.043 0.1657 0.1652
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0095 0.0293
Schistosoma mansoni microtubule-associated protein tau 0.1495 0.6002 0.6002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0537 0.2096 0.5834
Toxoplasma gondii cathepsin B 0.0903 0.3588 0.5229
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0145 0.0496 0.0496
Echinococcus multilocularis inhibitor of apoptosis protein 0.018 0.0638 0.0632
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0025
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Brugia malayi calpain 5 0.0539 0.2105 0.2105
Loa Loa (eye worm) hypothetical protein 0.0096 0.0295 0.0295
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.001 0.001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2475 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0052 0.0076
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0075 0.0069
Echinococcus multilocularis tumor protein p63 0.0366 0.1398 0.1393
Trypanosoma brucei cysteine peptidase C (CPC) 0.0903 0.3588 0.5229
Plasmodium falciparum serine repeat antigen 1 0.0199 0.0717 0.2347
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0224 0.0818 0.2267
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0439 0.0632
Giardia lamblia Cysteine protease 0.0199 0.0717 0.1985
Trypanosoma cruzi centrin, putative 0.0126 0.0418 0.0412
Brugia malayi Papain family cysteine protease containing protein 0.0199 0.0717 0.0717
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0204 0.0739 0.2418
Echinococcus multilocularis calpain 0.0763 0.3018 0.3014
Entamoeba histolytica calcium binding family protein 0.0122 0.0404 0.1312
Onchocerca volvulus 0.0768 0.3036 0.4423
Toxoplasma gondii preprocathepsin c precursor, putative 0.0199 0.0717 0.1038
Schistosoma mansoni peroxidasin 0.0064 0.0167 0.0167
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0075 0.0069
Schistosoma mansoni rab 0.0122 0.0404 0.0404
Mycobacterium tuberculosis Conserved protein 0.0036 0.0052 0.0076
Leishmania major hypothetical protein, conserved 0.0124 0.0412 0.0593
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0052
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2159 0.8709 0.8709
Plasmodium vivax metacaspase 1, putative 0.0341 0.1295 0.4253
Brugia malayi hypothetical protein 0.0253 0.0938 0.0938
Schistosoma mansoni survival motor neuron protein 0.0052 0.0116 0.0116
Mycobacterium leprae Conserved hypothetical protein 0.0211 0.0767 0.2661
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0739 0.0733
Schistosoma mansoni reticulocalbin 0.0122 0.0404 0.0404
Onchocerca volvulus Peroxidase homolog 0.0064 0.0167 0.0235
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0075 0.0074
Onchocerca volvulus 0.0089 0.0268 0.0382
Toxoplasma gondii cathepsin CPC1 0.0199 0.0717 0.1038
Plasmodium vivax vivapain-2 0.0768 0.3036 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Onchocerca volvulus 0.0211 0.0767 0.1111
Brugia malayi Papain family cysteine protease containing protein 0.0199 0.0717 0.0717
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0122 0.0404 0.0398
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0224 0.0818 0.1186
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Brugia malayi hypothetical protein 0.0093 0.0284 0.0283
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0045 0.0045
Schistosoma mansoni sodium/chloride dependent transporter 0.0524 0.2041 0.2041
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0847 0.3359 0.3355
Loa Loa (eye worm) hypothetical protein 0.0071 0.0194 0.0193
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0224 0.0818 0.2267
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0903 0.3588 1
Onchocerca volvulus Cathepsin L homolog 0.0768 0.3036 0.4423
Trypanosoma brucei centrin, putative 0.0122 0.0404 0.0581
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0199 0.0717 0.1985
Trichomonas vaginalis calcium binding protein, putative 0.0122 0.0404 0.111
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0075 0.0069
Trypanosoma cruzi metacaspase 5, putative 0.0341 0.1295 0.129
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0695 0.274 0.2735
Echinococcus granulosus neuronal calcium sensor 0.0122 0.0404 0.0398
Mycobacterium ulcerans proteasome PrcB 0.0088 0.0264 0.0811
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0075 0.0075
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0124 0.0124
Echinococcus granulosus calcium uptake protein 1 0.0124 0.0412 0.0407
Giardia lamblia Cathepsin B precursor 0.0199 0.0717 0.1985
Trichomonas vaginalis calmodulin-2, putative 0.0122 0.0404 0.111
Onchocerca volvulus Glycogen phosphorylase homolog 0.0108 0.0344 0.0493
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0026 0.0025
Echinococcus granulosus enteropeptidase 0.0145 0.0496 0.0491
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0496
Schistosoma mansoni Mername-AA248 (C02 family) 0.0763 0.3018 0.3018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Mycobacterium ulcerans hypothetical protein 0.0211 0.0767 0.2679
Mycobacterium ulcerans beta-lactamase 0.0036 0.0052 0.0025
Leishmania major centrin, putative 0.0122 0.0404 0.0581
Trichomonas vaginalis calcium binding protein, putative 0.0122 0.0404 0.111
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0052 0.0076
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0075 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Brugia malayi hypothetical protein 0.0042 0.0075 0.0074
Loa Loa (eye worm) prolyl oligopeptidase 0.0204 0.0739 0.0738
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0524 0.2041 0.2041
Trypanosoma cruzi Aph-1 protein, putative 0.0097 0.0302 0.0296
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Plasmodium falciparum amino acid transporter, putative 0.0089 0.0268 0.0864
Plasmodium falciparum transporter, putative 0.0089 0.0268 0.0864
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0075 0.0192
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0695 0.274 1
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1704 0.6856 1
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0075 0.0069
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0145 0.0496 0.0496
Schistosoma mansoni calmodulin 0.0122 0.0404 0.0404
Echinococcus granulosus peroxidasin 0.0064 0.0167 0.0161
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0096 0.0295 0.0295
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.029 0.0415
Brugia malayi hypothetical protein 0.0164 0.0573 0.0573
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2159 0.8709 0.8708
Brugia malayi Cell death protein 3 precursor 0.0596 0.2337 0.2337
Echinococcus multilocularis calpain 7 (C02 family) 0.0763 0.3018 0.3014
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0089 0.0268 0.0262
Loa Loa (eye worm) hypothetical protein 0.0071 0.0194 0.0193
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0199 0.0717 0.0717
Trypanosoma cruzi cysteine peptidase, putative 0.087 0.3452 0.3448
Echinococcus multilocularis calpain family protein 1, d 0.1497 0.6011 0.6008
Entamoeba histolytica prolyl oligopeptidase family protein 0.0204 0.0739 0.2418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0145 0.0496 0.0491
Leishmania major hypothetical protein, conserved 0.0224 0.0818 0.1186
Trypanosoma cruzi cysteine peptidase, putative 0.0768 0.3036 0.3032
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0124 0.0412 0.0407
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0204 0.0739 0.2418
Trichomonas vaginalis hypothetical protein 0.0224 0.0818 0.2267
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Schistosoma mansoni hypothetical protein 0.0046 0.0091 0.0091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.3014
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Echinococcus multilocularis apoptotic protease activating factor 1 0.0255 0.0947 0.0942
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.0006 0.0006
Onchocerca volvulus 0.0036 0.0052 0.0067
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0095 0.0184
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Loa Loa (eye worm) hypothetical protein 0.0042 0.0075 0.0074
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0768 0.3036 0.3036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Trichomonas vaginalis peptide N-glycanase, putative 0.0211 0.0767 0.2124
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0042 0.0078 0.0072
Leishmania major centrin, putative 0.0122 0.0404 0.0581
Trypanosoma brucei prolyl oligopeptidase, putative 0.0695 0.274 0.3991
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Toxoplasma gondii hypothetical protein 0.0089 0.0268 0.0382
Brugia malayi Pre-SET motif family protein 0.0654 0.2572 0.2572
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0768 0.3036 0.8459
Plasmodium vivax SET domain protein, putative 0.0094 0.029 0.0938
Echinococcus granulosus baculoviral IAP repeat containing protein 0.018 0.0638 0.0632
Echinococcus granulosus endothelin converting enzyme 1 0.0096 0.0295 0.0289
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Brugia malayi prolyl oligopeptidase family protein 0.0204 0.0739 0.0738
Trichomonas vaginalis conserved hypothetical protein 0.0224 0.0818 0.2267
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0224 0.0818 0.2267
Schistosoma mansoni cpg binding protein 0.003 0.0029 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.043 0.1657 0.545
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0167 0.0166
Schistosoma mansoni cathepsin B (C01 family) 0.0199 0.0717 0.0717
Onchocerca volvulus 0.0122 0.0404 0.0581
Trypanosoma brucei Calpain-like protein 1.2 0.0224 0.0818 0.1186
Echinococcus granulosus calpain A 0.0763 0.3018 0.3014
Loa Loa (eye worm) calpain 5 0.0539 0.2105 0.2105
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0089 0.0268 0.0262
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Trichomonas vaginalis centrin, putative 0.0122 0.0404 0.111
Onchocerca volvulus 0.0047 0.0099 0.0135
Loa Loa (eye worm) hypothetical protein 0.1273 0.5098 0.5098
Toxoplasma gondii calcium-dependent protein kinase 0.0124 0.0412 0.0593
Plasmodium falciparum calpain 0.0224 0.0818 0.2681
Echinococcus multilocularis microtubule associated protein 2 0.1495 0.6002 0.5999
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0068 0.0184 0.0586
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0199 0.0717 0.2347
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0089 0.0268 0.0262
Onchocerca volvulus 0.1273 0.5098 0.7433
Trypanosoma brucei prolyl endopeptidase 0.1704 0.6856 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0341 0.1295 0.3598
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0061 0.0269
Trypanosoma brucei calpain-like protein, putative 0.0763 0.3018 0.4397
Giardia lamblia Cathepsin L-like protease 0.0199 0.0717 0.1985
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.018 0.0638 0.0632
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0116 0.0116
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Plasmodium vivax vivapain-3 0.043 0.1657 0.545
Brugia malayi EF hand family protein 0.0122 0.0404 0.0403
Brugia malayi carbohydrate phosphorylase 0.0108 0.0344 0.0344
Brugia malayi Cathepsin L-like precursor 0.0537 0.2096 0.2096
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.001 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.029 0.029
Mycobacterium tuberculosis Long conserved protein 0.0211 0.0767 0.1265
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0537 0.2094 0.2089
Plasmodium vivax hypothetical protein, conserved 0.0341 0.1295 0.4253
Onchocerca volvulus 0.0029 0.0026 0.0028
Echinococcus granulosus tumor protein p63 0.0366 0.1398 0.1393
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0042 0.0078 0.0072
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.001 0.0006
Echinococcus multilocularis cathepsin L 0.043 0.1657 0.1652
Loa Loa (eye worm) hypothetical protein 0.0537 0.2096 0.2096
Entamoeba histolytica hypothetical protein 0.0042 0.0075 0.0226
Loa Loa (eye worm) hypothetical protein 0.0042 0.0075 0.0074
Mycobacterium leprae probable zinc metalloprotease 0.0096 0.0295 0.0905
Schistosoma mansoni neprilysin 0.0025 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.043 0.1657 0.2411
Brugia malayi proteasome subunit beta type 2 0.0042 0.0078 0.0078
Plasmodium falciparum cysteine proteinase falcipain 3 0.0768 0.3036 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Onchocerca volvulus 0.0768 0.3036 0.4423
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0052 0.0128
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0052 0.0128
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0025
Onchocerca volvulus 0.0768 0.3036 0.4423
Schistosoma mansoni calpain-2 (C02 family) 0.0224 0.0818 0.0818
Loa Loa (eye worm) hypothetical protein 0.0072 0.02 0.02
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0096 0.0295 0.0295
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0199 0.0717 0.1985
Brugia malayi Protein kinase domain containing protein 0.0046 0.0091 0.0091
Echinococcus granulosus EF HAND 1 calcium binding site 0.0122 0.0404 0.0398
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0167 0.0166
Brugia malayi programmed cell death protein 6 0.0122 0.0404 0.0403
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0122 0.0404 0.0398
Trichomonas vaginalis esterase, putative 0.0036 0.0052 0.0128
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0075 0.0069
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0199 0.0717 0.2347
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0344 0.0338
Onchocerca volvulus 0.018 0.0638 0.0922
Brugia malayi MH2 domain containing protein 0.0119 0.0391 0.0391
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0089 0.0268 0.0268
Giardia lamblia Cathepsin L precursor 0.0199 0.0717 0.1985
Echinococcus multilocularis cpg binding protein 0.0032 0.0036 0.003
Trypanosoma brucei Metacaspase-4 0.0341 0.1295 0.1881
Echinococcus multilocularis peroxidasin 0.0064 0.0167 0.0161
Brugia malayi Kringle domain containing protein 0.0046 0.0091 0.0091
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0763 0.3018 0.3014
Plasmodium vivax hypothetical protein, conserved 0.0204 0.0739 0.2418
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0167 0.0166
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0075 0.0074
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2036 0.821 0.821
Loa Loa (eye worm) programmed cell death protein 6 0.0124 0.0412 0.0412
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0122 0.0404 0.1312
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0075 0.0075
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0089 0.0268 0.0262
Echinococcus multilocularis calmodulin 0.0122 0.0404 0.0398
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0102 0.0102
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.029 0.029
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0075 0.0069
Loa Loa (eye worm) hypothetical protein 0.0145 0.0496 0.0496
Schistosoma mansoni calpain C (C02 family) 0.0763 0.3018 0.3018
Echinococcus multilocularis cathepsin L cysteine protease 0.0768 0.3036 0.3032
Echinococcus granulosus caspase 0.0847 0.3359 0.3355
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0199 0.0717 0.0717
Echinococcus granulosus centrin 2 0.0122 0.0404 0.0398
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0075 0.0075
Brugia malayi Peptidase family M13 containing protein 0.0096 0.0295 0.0295
Onchocerca volvulus 0.0255 0.0947 0.1374
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0297 0.1117 0.1112
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.0818 0.0813
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0122 0.0404 0.0398
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0194 0.0193
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0199 0.0717 0.1985
Onchocerca volvulus Cell death protein 3 homolog 0.0596 0.2337 0.3403
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0089 0.0268 0.0268
Trypanosoma brucei centrin, putative 0.0122 0.0404 0.0581
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0199 0.0717 0.2347
Echinococcus granulosus cysteine protease 0.043 0.1657 0.1652
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.043 0.1657 0.1652
Brugia malayi Cathepsin L-like precursor 0.0231 0.0846 0.0845
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0344 0.0943
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0167 0.0235
Trichomonas vaginalis calpain, putative 0.0224 0.0818 0.2267
Echinococcus multilocularis enteropeptidase 0.0145 0.0496 0.0491
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1295 0.3598
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0199 0.0717 0.1985
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2475 1 1
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0046 0.0091 0.0281
Echinococcus multilocularis EF hand domain containing family member A2 0.0124 0.0412 0.0407
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0837 0.3317 0.3313
Brugia malayi cathepsin Z-like cysteine proteinase 0.0199 0.0717 0.0717
Onchocerca volvulus 0.0029 0.0026 0.0028
Brugia malayi Probable ATP-dependent helicase DHX35 0.0097 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0537 0.2096 0.2096
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0075 0.0069
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Trypanosoma cruzi cysteine proteinase, putative 0.043 0.1657 0.1652
Leishmania major calpain protease-like protein 0.0224 0.0818 0.1186
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.043 0.1657 0.1657
Plasmodium falciparum serine repeat antigen 3 0.0199 0.0717 0.2347
Onchocerca volvulus 0.003 0.0029 0.0034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0199 0.0717 0.0717
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0075 0.0074
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0042 0.0078 0.0072
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0285 0.0279
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.043 0.1657 0.1657
Plasmodium falciparum serine repeat antigen 9 0.0199 0.0717 0.2347
Echinococcus granulosus cathepsin b 0.2475 1 1
Brugia malayi Thioredoxin family protein 0.0211 0.0767 0.0767
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0695 0.274 0.4544
Echinococcus multilocularis dnaJ subfamily B 0.0433 0.1671 0.1665
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0297 0.1117 0.1622
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1295 0.3598
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.001 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0052 0.0046
Plasmodium falciparum cysteine repeat modular protein 1 0.0046 0.0091 0.0281
Brugia malayi hypothetical protein 0.0089 0.0268 0.0268
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0029 0.0029
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0439 0.0433
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0078 0.0078
Schistosoma mansoni cpg binding protein 0.0032 0.0036 0.0036
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0075 0.0075
Schistosoma mansoni cathepsin F (C01 family) 0.0768 0.3036 0.3036
Onchocerca volvulus 0.0029 0.0026 0.0028
Onchocerca volvulus 0.0145 0.0496 0.0716
Toxoplasma gondii hypothetical protein 0.0224 0.0818 0.1186
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0052 0.0076
Loa Loa (eye worm) hypothetical protein 0.2036 0.821 0.821
Echinococcus multilocularis cathepsin L 0.0199 0.0717 0.0712
Loa Loa (eye worm) hypothetical protein 0.0537 0.2096 0.2096
Toxoplasma gondii proteasome subunit beta type, putative 0.0088 0.0264 0.0376
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.4397
Trypanosoma brucei hypothetical protein 0.0224 0.0818 0.1186
Loa Loa (eye worm) hypothetical protein 0.0072 0.02 0.02
Leishmania major cathepsin L-like protease 0.087 0.3452 0.503
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0122 0.0404 0.0398
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0382
Mycobacterium tuberculosis Hypothetical protein 0.0211 0.0767 0.1265
Toxoplasma gondii cathepsin CPC2 0.0199 0.0717 0.1038
Loa Loa (eye worm) hypothetical protein 0.0042 0.0075 0.0074
Mycobacterium ulcerans hypothetical protein 0.0036 0.0052 0.0025
Onchocerca volvulus Peroxidase homolog 0.0064 0.0167 0.0235
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0007 0.0007
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0089 0.0268 0.0268
Echinococcus granulosus inhibitor of apoptosis protein 0.018 0.0638 0.0632
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0496 0.0496
Leishmania major oligopeptidase b 0.0695 0.274 0.3991
Giardia lamblia Proteasome subunit beta type 1 0.0068 0.0184 0.0496
Giardia lamblia Proteasome subunit beta type 2 0.0042 0.0078 0.02
Brugia malayi Cathepsin L-like cysteine proteinase 0.0537 0.2096 0.2096
Brugia malayi Papain family cysteine protease containing protein 0.043 0.1657 0.1657
Schistosoma mansoni caspase-7 (C14 family) 0.0847 0.3359 0.3359
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0075 0.0192
Onchocerca volvulus 0.0145 0.0496 0.0716
Echinococcus granulosus EF hand domain containing family member A2 0.0122 0.0404 0.0398
Loa Loa (eye worm) hypothetical protein 0.2475 1 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0052
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0075 0.0075
Onchocerca volvulus Prolyl endopeptidase homolog 0.1704 0.6856 1
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0075 0.0075
Brugia malayi cathepsin L-like precursor 0.0537 0.2096 0.2096
Brugia malayi Trypsin family protein 0.0145 0.0496 0.0496
Brugia malayi Blistered cuticle protein 3 0.0064 0.0167 0.0166
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0052 0.0067
Loa Loa (eye worm) hypothetical protein 0.0524 0.2041 0.2041
Echinococcus multilocularis caspase 3 0.0506 0.1969 0.1964
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0167 0.0166
Leishmania major hypothetical protein, conserved 0.0046 0.0091 0.0124
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0199 0.0717 0.2347
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0285 0.0285
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0096 0.0295 0.048
Toxoplasma gondii troponin c, isotype gamma, putative 0.0122 0.0404 0.0581
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0026 0.0028
Onchocerca volvulus 0.0064 0.0167 0.0235
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0025
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0224 0.0818 0.2267
Plasmodium falciparum centrin-1 0.0122 0.0404 0.1312
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0204 0.0739 0.107
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0075 0.0069
Trichomonas vaginalis myosin light chain 1, putative 0.0122 0.0404 0.111
Echinococcus multilocularis caspase 2 0.0596 0.2337 0.2332
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0045 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0204 0.0739 0.2045
Schistosoma mansoni hypothetical protein 0.0211 0.0767 0.0767
Giardia lamblia Cathepsin L precursor 0.0199 0.0717 0.1985
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0026 0.0028
Schistosoma mansoni sodium/chloride dependent transporter 0.0089 0.0268 0.0268
Trypanosoma cruzi cruzipain precursor, putative 0.0231 0.0846 0.084
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0199 0.0717 0.2347
Loa Loa (eye worm) hypothetical protein 0.0097 0.0301 0.0301
Schistosoma mansoni sodium-dependent amino acid transporter 0.0089 0.0268 0.0268
Brugia malayi Proteasome A-type and B-type family protein 0.0088 0.0264 0.0263
Toxoplasma gondii cathepsin CPL 0.0768 0.3036 0.4423
Brugia malayi calpain D 0.0224 0.0818 0.0818
Schistosoma mansoni cathepsin s 0.0231 0.0846 0.0846
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0052 0.0128
Loa Loa (eye worm) DEAH box polypeptide 35 0.0097 0.0301 0.0301
Leishmania major hypothetical protein, unknown function 0.0224 0.0818 0.1186
Entamoeba histolytica grainin 2 0.0126 0.0418 0.1359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Entamoeba histolytica cysteine proteinase 2 0.043 0.1657 0.545
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0182 0.0182
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0391 0.1501 0.1496
Trypanosoma brucei protein I/6 0.0122 0.0404 0.0581
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.0818 0.0813
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Plasmodium vivax vivapain-1 0.043 0.1657 0.545
Mycobacterium ulcerans hypothetical protein 0.0145 0.0496 0.1674
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0224 0.0818 0.1186
Loa Loa (eye worm) proteasome subunit beta type 2 0.0042 0.0078 0.0078
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0075 0.0075
Giardia lamblia Cathepsin B precursor 0.0199 0.0717 0.1985
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2159 0.8709 0.8709
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0204 0.0739 0.0739
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0075 0.0069
Giardia lamblia Transglutaminase/protease, putative 0.0211 0.0767 0.2124
Echinococcus granulosus tissue type plasminogen activator 0.0046 0.0091 0.0085
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0167 0.0235
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0695 0.274 0.3991
Trypanosoma brucei hypothetical protein, conserved 0.0122 0.0404 0.0581
Loa Loa (eye worm) hypothetical protein 0.0064 0.0167 0.0166
Onchocerca volvulus 0.0029 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0224 0.0818 0.0818
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0695 0.274 0.2735
Mycobacterium ulcerans transglutaminase family protein 0.0211 0.0767 0.2679
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0847 0.3359 0.3355
Toxoplasma gondii kringle domain-containing protein 0.0046 0.0091 0.0124
Onchocerca volvulus 0.0768 0.3036 0.4423
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0341 0.1295 0.1295
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0078 0.0078
Giardia lamblia Alanyl dipeptidyl peptidase 0.0204 0.0739 0.2045
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0122 0.0404 0.0581
Loa Loa (eye worm) hypothetical protein 0.1704 0.6856 0.6856
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0167 0.0235
Brugia malayi PXA domain containing protein 0.0042 0.0075 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0089 0.0268 0.0268
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0439 0.0632
Echinococcus multilocularis programmed cell death protein 0.0126 0.0418 0.0412
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0068 0.0184 0.0496
Brugia malayi Cytochrome P450 family protein 0.0057 0.0137 0.0136
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.001 0.0011
Leishmania major calmodulin-like protein 0.0122 0.0404 0.0581
Brugia malayi PAN domain containing protein 0.0029 0.0026 0.0025
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0496
Loa Loa (eye worm) hypothetical protein 0.0524 0.2041 0.2041
Brugia malayi Cytochrome P450 family protein 0.0034 0.0045 0.0045
Echinococcus granulosus programmed cell death protein 0.0126 0.0418 0.0412
Toxoplasma gondii prolyl endopeptidase 0.1704 0.6856 1
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0075 0.0069
Entamoeba histolytica calpain family cysteine protease, putative 0.0224 0.0818 0.2681
Giardia lamblia Hypothetical protein 0.0211 0.0767 0.2124
Leishmania major cysteine peptidase A (CPA) 0.0768 0.3036 0.4423
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0344 0.0338
Loa Loa (eye worm) hypothetical protein 0.0145 0.0496 0.0496
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0052 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0006
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0089 0.0268 0.0268
Trypanosoma cruzi cysteine protease, putative 0.043 0.1657 0.1652
Plasmodium vivax vivapain-2 0.0768 0.3036 1
Entamoeba histolytica cysteine proteinase, putative 0.043 0.1657 0.545
Trypanosoma brucei Calpain-like protein 1.1 0.0224 0.0818 0.1186
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0341 0.1295 0.1295
Loa Loa (eye worm) hypothetical protein 0.0072 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0253 0.0938 0.0938
Schistosoma mansoni hypothetical protein 0.0255 0.0947 0.0947
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0068 0.0184 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0199 0.0717 0.1985
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0075 0.0074
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0061 0.0181
Trichomonas vaginalis centrin, putative 0.0122 0.0404 0.111
Brugia malayi calpain family protein 1 0.2036 0.821 0.821
Echinococcus multilocularis Transglutaminase 0.0211 0.0767 0.0761
Onchocerca volvulus 0.0768 0.3036 0.4423
Loa Loa (eye worm) solute carrier family 6 member 4 0.0524 0.2041 0.2041
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0075 0.0075
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0052 0.0046
Echinococcus multilocularis neuronal calcium sensor 0.0122 0.0404 0.0398
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0297 0.1117 0.1622
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0194 0.0193
Loa Loa (eye worm) hypothetical protein 0.0042 0.0075 0.0074
Entamoeba histolytica cysteine proteinase, putative 0.0768 0.3036 1
Schistosoma mansoni neuronal calcium sensor 0.0122 0.0404 0.0404
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.0813
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0199 0.0717 0.1985
Trypanosoma cruzi Aph-1 protein, putative 0.0097 0.0302 0.0296
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0204 0.0739 0.107
Onchocerca volvulus Cathepsin L homolog 0.0199 0.0717 0.1038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.0818 0.1186
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0102 0.0102
Brugia malayi Pre-SET motif family protein 0.0094 0.029 0.029
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0075 0.0069
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0763 0.3018 0.3014
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0391 0.1501 0.1501
Trichomonas vaginalis calpain, putative 0.0224 0.0818 0.2267
Mycobacterium tuberculosis Possible penicillin-binding protein 0.023 0.0842 0.139
Echinococcus granulosus serotonin transporter 0.0524 0.2041 0.2036
Trypanosoma cruzi I/6 autoantigen, putative 0.0122 0.0404 0.0398
Onchocerca volvulus 0.0537 0.2096 0.3051
Brugia malayi hypothetical protein 0.0255 0.0947 0.0947
Echinococcus multilocularis proteasome (prosome, macropain) 0.0088 0.0264 0.0258
Entamoeba histolytica calpain large subunit domain III containing protein 0.0539 0.2105 0.6927
Brugia malayi cathepsin F-like cysteine proteinase 0.0231 0.0846 0.0845
Giardia lamblia Hypothetical protein 0.0124 0.0412 0.1134
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0739 0.0733
Mycobacterium leprae Conserved hypothetical protein 0.0211 0.0767 0.2661
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0075 0.0192
Echinococcus multilocularis acylamino acid releasing enzyme 0.0204 0.0739 0.0733
Schistosoma mansoni hypothetical protein 0.0025 0.0007 0.0007
Schistosoma mansoni caspase-3 (C14 family) 0.0847 0.3359 0.3359
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0061 0.0153
Giardia lamblia Cathepsin L precursor 0.0199 0.0717 0.1985
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0137 0.0136
Brugia malayi Cathepsin L-like precursor 0.0768 0.3036 0.3036
Brugia malayi beta-lactamase family protein 0.0036 0.0052 0.0052
Echinococcus multilocularis sodium and chloride dependent glycine 0.0089 0.0268 0.0262
Brugia malayi hypothetical protein 0.0064 0.0167 0.0166
Onchocerca volvulus 0.0029 0.0026 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Giardia lamblia Cysteine protease 0.0199 0.0717 0.1985
Loa Loa (eye worm) hypothetical protein 0.0524 0.2041 0.2041
Echinococcus granulosus neurocalcin 0.0122 0.0404 0.0398
Toxoplasma gondii microneme protein MIC4 0.0029 0.0026 0.0028
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0903 0.3588 0.3584
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.001 0.0006
Toxoplasma gondii EFHC1, putative 0.0122 0.0404 0.0581
Echinococcus granulosus cathepsin l cysteine peptidase 0.0768 0.3036 0.3032
Plasmodium falciparum metacaspase-like protein 0.0341 0.1295 0.4253
Echinococcus granulosus calumenin 0.0124 0.0412 0.0407
Schistosoma mansoni reticulocalbin 0.0124 0.0412 0.0412
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0496 0.0496
Trichomonas vaginalis calmodulin, putative 0.0122 0.0404 0.111
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0167 0.0166
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0122 0.0404 0.0398
Entamoeba histolytica cysteine protease, putative 0.043 0.1657 0.545
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0224 0.0818 0.1186
Onchocerca volvulus Cathepsin F homolog 0.0768 0.3036 0.4423
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0048 0.0102 0.0102
Onchocerca volvulus 0.0036 0.0052 0.0067
Loa Loa (eye worm) hypothetical protein 0.0199 0.0717 0.0717
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Trypanosoma brucei antigen, putative 0.0763 0.3018 0.4397
Giardia lamblia Cysteine protease 0.0199 0.0717 0.1985
Echinococcus multilocularis Mastin 0.0145 0.0496 0.0491
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0537 0.2094 0.3048
Echinococcus granulosus proteasome prosome macropain 0.0088 0.0264 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.087 0.3452 0.503
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1295 0.3598
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0088 0.0264 0.085
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0075 0.0074
Schistosoma mansoni memapsin-2 (A01 family) 0.0456 0.1767 0.1767
Schistosoma mansoni hypothetical protein 0.0224 0.0818 0.0818
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0768 0.3036 0.8459
Loa Loa (eye worm) hypothetical protein 0.0042 0.0075 0.0074
Echinococcus granulosus flap endonuclease 1 0.0026 0.001 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0075 0.0192
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0068 0.0184 0.0586
Entamoeba histolytica cysteine protease, putative 0.0199 0.0717 0.2347
Loa Loa (eye worm) hypothetical protein 0.0093 0.0284 0.0283
Trypanosoma cruzi cruzipain precursor, putative 0.087 0.3452 0.3448
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0768 0.3036 0.8459
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0089 0.0268 0.0268
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0052 0.0025
Loa Loa (eye worm) hypothetical protein 0.0341 0.1295 0.1295
Trypanosoma brucei kinesin, putative 0.0539 0.2105 0.3064

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.05 nM In vitro inhibitory concentration of the compound that inhibits 50% of the growth of MCF-7 human breast cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 0.05 nM In vitro inhibitory concentration of the compound that inhibits 50% of the growth of MCF-7 human breast cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 0.09 nM In vitro inhibitory concentration of the compound that inhibits 50% of the growth of A549 non small cell lung carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 0.09 nM In vitro inhibitory concentration of the compound that inhibits 50% of the growth of A549 non small cell lung carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 0.4 nM Inhibitory concentration of the compound that inhibits 50% of the growth of MCF-7 human breast cell carcinoma cell line after 72 h of drug exposure.(Table 3) ChEMBL. 15369381
IC50 (functional) = 0.4 nM Inhibitory concentration of the compound that inhibits 50% of the growth of MCF-7 human breast cell carcinoma cell line after 72 h of drug exposure.(Table 3) ChEMBL. 15369381
IC50 (functional) = 0.53 nM Inhibitory concentration of the compound that inhibits 50% of the growth of Namalwa Burkitts lymphoma cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 0.65 nM Inhibitory concentration of the compound that inhibits 50% of the growth of Namalwa MDR Burkitts lymphoma MDR cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 1 nM Inhibitory concentration of the compound that inhibits 50% of the growth of LCC6/P9 human breast cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 1 nM Inhibitory concentration of the compound that inhibits 50% of the growth of LCC6/P9 human breast cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 4 nM Inhibitory concentration of the compound that inhibits 50% of the growth of LGM MDR human breast cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 15 nM Inhibitory concentration of the compound that inhibits 50% of the growth of NCI ADR RES human breast cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
IC50 (functional) = 15 nM Inhibitory concentration of the compound that inhibits 50% of the growth of NCI ADR RES human breast cell carcinoma cell line after 72 h of drug exposure. ChEMBL. 15369381
Ratio (functional) 1.2 Ratio of activities against drug resistant to drug sensitive cell lines ChEMBL. 15369381
Ratio (functional) 4 Ratio of activities against drug resistant to drug sensitive cell lines ChEMBL. 15369381
Ratio (functional) 37.5 Ratio of activities against drug resistant to drug sensitive cell lines ChEMBL. 15369381
S = 8 ug ml-1 Solubility of the compound in 10% DMA(expressed as mean of 3 determinations) ChEMBL. 15369381
S = 10 ug ml-1 Solubility of the compound in 10% Ethanol(expressed as mean of 3 determinations) ChEMBL. 15369381
S = 14 ug ml-1 Solubility of the compound in 10% DMSO(expressed as mean of 3 determinations) ChEMBL. 15369381

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 15369381

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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