Detailed information for compound 331604

Basic information

Technical information
  • TDR Targets ID: 331604
  • Name: (1S,3S,5S)-4-[(2S)-azetidine-2-carbonyl]-4-az abicyclo[3.1.0]hexane-3-carbonitrile
  • MW: 191.23 | Formula: C10H13N3O
  • H donors: 1 H acceptors: 2 LogP: -0.1 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#C[C@@H]1C[C@H]2[C@@H](N1C(=O)[C@@H]1CCN1)C2
  • InChi: 1S/C10H13N3O/c11-5-7-3-6-4-9(6)13(7)10(14)8-1-2-12-8/h6-9,12H,1-4H2/t6-,7+,8+,9+/m1/s1
  • InChiKey: TYVFRLPOUVPKDW-XGEHTFHBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1S,3S,5S)-4-[[(2S)-2-azetidinyl]-oxomethyl]-4-azabicyclo[3.1.0]hexane-3-carbonitrile
  • (1S,3S,5S)-4-[(2S)-azetidin-2-yl]carbonyl-4-azabicyclo[3.1.0]hexane-3-carbonitrile

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0033 0.0033
Leishmania major protein kinase, putative 0.0306 0.0408 0.1175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Onchocerca volvulus Cathepsin F homolog 0.129 0.1801 0.3964
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0091 0.0104 0.0104
Plasmodium vivax unspecified product 0.0358 0.0482 0.1791
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.5452 0.7693 0.7693
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0005 0.0005
Echinococcus multilocularis Calcium binding protein 0.0027 0.0013 0.0013
Plasmodium falciparum GPI-anchor transamidase, putative 0.0141 0.0174 0.0968
Echinococcus granulosus endothelin converting enzyme 1 0.0094 0.0109 0.0109
Entamoeba histolytica calmodulin, putative 0.0027 0.0013 0.0071
Echinococcus granulosus programmed cell death protein 6 0.0032 0.002 0.002
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0033 0.0033
Echinococcus multilocularis dnaJ subfamily B 0.0427 0.058 0.058
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0018 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Entamoeba histolytica hypothetical protein, conserved 0.031 0.0414 0.217
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.004 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0095 0.0109 0.0109
Onchocerca volvulus Cathepsin L homolog 0.0406 0.0551 0.1212
Trichomonas vaginalis conserved hypothetical protein 0.0406 0.0551 0.1585
Echinococcus multilocularis calmodulin 0.0306 0.0408 0.0408
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.7753
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0006 0.0006
Loa Loa (eye worm) calmodulin-like protein 0.0306 0.0408 0.0408
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.0027 0.0013 0.007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.7082 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0071 0.0076 0.0076
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0764 0.1057 0.1057
Trypanosoma cruzi cysteine peptidase, putative 0.129 0.1801 0.1801
Schistosoma mansoni reticulocalbin 0.031 0.0414 0.0414
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0178 0.0227 0.0227
Onchocerca volvulus Deterin homolog 0.0178 0.0227 0.0499
Trypanosoma cruzi calmodulin, putative 0.0306 0.0408 0.0408
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0406 0.0551 0.1585
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.7753
Trypanosoma brucei calmodulin, putative 0.031 0.0414 0.1193
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0129 0.0674
Brugia malayi Flap endonuclease-1 0.0025 0.0011 0.0011
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0406 0.0551 0.0551
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0298 0.0397 0.0397
Brugia malayi calpain 5 0.1367 0.191 0.191
Echinococcus multilocularis cysteine protease 0.129 0.1801 0.1801
Plasmodium falciparum cysteine proteinase falcipain 2a 0.129 0.1801 1
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0022 0.0064
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Brugia malayi Serine carboxypeptidase S28 family protein 0.0021 0.0005 0.0005
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Toxoplasma gondii proteasome subunit beta type, putative 0.0089 0.0101 0.029
Entamoeba histolytica cysteine proteinase, putative 0.0764 0.1057 0.5536
Trypanosoma cruzi centrin, putative 0.0333 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.004 0.0032 0.0032
Brugia malayi Cytochrome P450 family protein 0.0034 0.0023 0.0023
Brugia malayi Blistered cuticle protein 3 0.0065 0.0067 0.0067
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0067 0.0067
Entamoeba histolytica cysteine protease, putative 0.0406 0.0551 0.2882
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0406 0.0551 0.2045
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0406 0.0551 0.2045
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0129 0.0371
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0406 0.0551 0.0551
Echinococcus granulosus calumenin 0.031 0.0414 0.0414
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0298 0.0397 0.0397
Entamoeba histolytica cysteine protease, putative 0.0406 0.0551 0.2882
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0406 0.0551 0.1585
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0036 0.0036
Trypanosoma brucei calpain-like protein, putative 0.192 0.2693 0.7753
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0764 0.1057 0.3045
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0011 0.0011
Brugia malayi proteasome subunit beta type 1 0.0069 0.0073 0.0073
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.1294 0.3726
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0553 0.0758 0.0758
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0025 0.0259
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0104 0.0104
Toxoplasma gondii centrin, putative 0.0306 0.0408 0.1175
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0132 0.0162 0.0467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.2693
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0006 0.0006
Brugia malayi prolyl oligopeptidase family protein 0.0205 0.0266 0.0266
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0006 0.0006
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0089 0.0101 0.0101
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0033 0.0033
Giardia lamblia GPI-anchor transamidase, putative 0.0141 0.0174 0.0502
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0306 0.0408 0.0408
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0008 0.0046
Mycobacterium tuberculosis Hypothetical protein 0.0035 0.0025 0.0118
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0094 0.0109 0.0516
Loa Loa (eye worm) hypothetical protein 0.0047 0.0041 0.0041
Trichomonas vaginalis myosin light chain 1, putative 0.0306 0.0408 0.1175
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0109 0.0109
Plasmodium vivax aspartyl protease, putative 0.0018 0.0002 0.0006
Loa Loa (eye worm) AStacin protease 0.0029 0.0016 0.0016
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0298 0.0397 0.1142
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0129 0.0129
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0011 0.0011
Onchocerca volvulus 0.0134 0.0165 0.0364
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0298 0.0397 0.1142
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0698 0.0964 0.2776
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0013 0.0013
Plasmodium falciparum serine repeat antigen 5 0.0406 0.0551 0.3057
Brugia malayi aspartic protease BmAsp-2, identical 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0306 0.0408 0.1175
Plasmodium vivax centrin-1, putative 0.0306 0.0408 0.1515
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0027 0.0013 0.0039
Schistosoma mansoni calmodulin 0.0306 0.0408 0.0408
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0006 0.0006
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0306 0.0408 0.0408
Schistosoma mansoni microtubule-associated protein tau 0.1492 0.2088 0.2088
Echinococcus multilocularis cathepsin L cysteine protease 0.129 0.1801 0.1801
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0698 0.0964 0.0964
Echinococcus granulosus flap endonuclease 1 0.0025 0.0011 0.0011
Echinococcus granulosus acylamino acid releasing enzyme 0.0205 0.0266 0.0266
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0022 0.0064
Trypanosoma brucei protein I/6 0.0306 0.0408 0.1175
Trypanosoma cruzi cysteine peptidase, putative 0.0764 0.1057 0.1057
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0553 0.0758 0.0758
Echinococcus granulosus Mastin 0.0091 0.0104 0.0104
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0537 0.0735 0.0735
Leishmania major cathepsin L-like protease 0.129 0.1801 0.5185
Schistosoma mansoni survival motor neuron protein 0.0052 0.0049 0.0049
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Trichomonas vaginalis calmodulin, putative 0.0306 0.0408 0.1175
Echinococcus multilocularis acylamino acid releasing enzyme 0.0205 0.0266 0.0266
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0033 0.0033
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0109 0.0109
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0162 0.1682
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.031 0.0414 0.0414
Entamoeba histolytica cysteine proteinase, putative 0.0764 0.1057 0.5536
Plasmodium falciparum plasmepsin II 0.0018 0.0002 0.0008
Echinococcus granulosus calmodulin 0.0306 0.0408 0.0408
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0553 0.0758 0.0758
Plasmodium falciparum centrin-1 0.0306 0.0408 0.2265
Onchocerca volvulus 0.0306 0.0408 0.0898
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0406 0.0551 0.1585
Plasmodium vivax vivapain-3 0.0764 0.1057 0.3927
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0008 0.0008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0032 0.0032
Echinococcus multilocularis Mastin 0.0091 0.0104 0.0104
Toxoplasma gondii peptidase family M13 protein 0.0094 0.0109 0.0313
Leishmania major centrin, putative,caltractin, putative 0.0306 0.0408 0.1175
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.3227 0.4543 0.4543
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0005 0.0025
Mycobacterium ulcerans proteasome PrcB 0.0089 0.0101 0.1046
Onchocerca volvulus 0.0047 0.0041 0.0091
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Schistosoma mansoni neuronal calcium sensor 0.0306 0.0408 0.0408
Brugia malayi hypothetical protein 0.0091 0.0104 0.0104
Trypanosoma cruzi caltractin, putative 0.0306 0.0408 0.0408
Brugia malayi Peroxidasin 0.0065 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0553 0.0758 0.2182
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.0758 0.0758
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0406 0.0551 0.1585
Schistosoma mansoni calpain-7 (C02 family) 0.1922 0.2697 0.2697
Brugia malayi beta-lactamase 0.004 0.0032 0.0032
Brugia malayi Peptidase C13 family protein 0.0606 0.0833 0.0833
Leishmania major calmodulin-like protein 0.0306 0.0408 0.1175
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0104 0.0104
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.192 0.2693 0.2693
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, putative 0.0553 0.0758 0.2182
Plasmodium falciparum proteasome subunit beta type-5 0.0089 0.0101 0.056
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0073 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.028 0.0372 0.0372
Brugia malayi calpain 7 0.192 0.2693 0.2693
Brugia malayi hypothetical protein 0.0256 0.0337 0.0337
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0006 0.0006
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0764 0.1057 0.1057
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0258 0.034 0.1612
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Giardia lamblia Alanyl dipeptidyl peptidase 0.0205 0.0266 0.0765
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0033 0.0033
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0033 0.0033
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0006 0.0006
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0553 0.0758 0.0758
Loa Loa (eye worm) hypothetical protein 0.0406 0.0551 0.0551
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Plasmodium falciparum importin beta, putative 0.0033 0.0022 0.0123
Mycobacterium ulcerans hypothetical protein 0.0035 0.0025 0.0259
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Leishmania major calpain family cysteine protease-like protein 0.0553 0.0758 0.2182
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0022
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0032 0.0093
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0089 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Echinococcus granulosus Dipeptidyl peptidase 9 0.0298 0.0397 0.0397
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0018 0.0002 0.0002
Echinococcus granulosus prolyl endopeptidase 0.1713 0.24 0.24
Trichomonas vaginalis conserved hypothetical protein 0.0553 0.0758 0.2182
Loa Loa (eye worm) calpain family protein 1 0.3779 0.5325 0.5325
Trypanosoma brucei calpain-like protein, putative 0.192 0.2693 0.7753
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0033
Plasmodium falciparum plasmepsin VII 0.0018 0.0002 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0306 0.0408 0.1175
Schistosoma mansoni mitochondrial solute carrier 0.0306 0.0408 0.0408
Onchocerca volvulus 0.129 0.1801 0.3964
Toxoplasma gondii calcium binding protein precursor, putative 0.0027 0.0013 0.0039
Echinococcus granulosus GPCR family 2 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0606 0.0833 0.2399
Echinococcus multilocularis gamma secretase subunit aph 1 0.028 0.0372 0.0372
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0074 0.0074
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Plasmodium falciparum plasmepsin X 0.0018 0.0002 0.0008
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0091 0.0104 0.0104
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0306 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0091 0.0104 0.0104
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0089 0.0101 0.0101
Trichomonas vaginalis calcineurin B subunit, putative 0.031 0.0414 0.1193
Loa Loa (eye worm) myosin Light Chain family member 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0013
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Toxoplasma gondii centrin 0.0306 0.0408 0.1175
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0033 0.0033
Echinococcus multilocularis tumor protein p63 0.0361 0.0487 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0032 0.0154
Trypanosoma cruzi conserved protein 0.0553 0.0758 0.0758
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0033 0.0096
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0091 0.0104 0.0104
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0056 0.0056
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.5146 0.726 0.726
Trichomonas vaginalis esterase, putative 0.004 0.0032 0.0093
Schistosoma mansoni hypothetical protein 0.0039 0.0031 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0109 0.0109
Loa Loa (eye worm) MH2 domain-containing protein 0.0137 0.0169 0.0169
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0089 0.0101 0.029
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0036 0.0199
Giardia lamblia Cathepsin B precursor 0.0406 0.0551 0.1585
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0003 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0013
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0032 0.0154
Toxoplasma gondii EF hand domain-containing protein 0.0306 0.0408 0.1175
Brugia malayi hypothetical protein 0.0092 0.0106 0.0106
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0113 0.0113
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0094 0.0109 0.0109
Plasmodium falciparum cysteine proteinase falcipain 2b 0.129 0.1801 1
Schistosoma mansoni cathepsin s 0.0358 0.0482 0.0482
Loa Loa (eye worm) cathepsin B 0.2471 0.3473 0.3473
Trypanosoma brucei antigen, putative 0.192 0.2693 0.7753
Leishmania major programmed cell death 6 protein-like protein 0.0306 0.0408 0.1175
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0036 0.0103
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Brugia malayi Cytochrome P450 family protein 0.0056 0.0055 0.0055
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0298 0.0397 0.0397
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0141 0.0174 0.0502
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0406 0.0551 0.2045
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0266 0.0266
Plasmodium vivax unspecified product 0.0406 0.0551 0.2045
Schistosoma mansoni calpain-2 (C02 family) 0.0553 0.0758 0.0758
Loa Loa (eye worm) hypothetical protein 0.0358 0.0482 0.0482
Giardia lamblia Cathepsin L precursor 0.0406 0.0551 0.1585
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Mycobacterium leprae conserved hypothetical protein 0.004 0.0032 0.0336
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0427 0.058 0.058
Trichomonas vaginalis hypothetical protein 0.0553 0.0758 0.2182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0032 0.0093
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.3779 0.5325 0.5325
Onchocerca volvulus 0.0932 0.1294 0.2848
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0003 0.0003
Echinococcus multilocularis cpg binding protein 0.0032 0.002 0.002
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0018 0.0002 0.0002
Schistosoma mansoni ap endonuclease 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.007 0.0074 0.0074
Loa Loa (eye worm) EF hand family protein 0.0306 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0071 0.0076 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0006 0.0006
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0033 0.0033
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0109 0.0109
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.0337 0.0337
Onchocerca volvulus 0.129 0.1801 0.3964
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.5452 0.7693 0.7693
Trypanosoma cruzi cysteine proteinase, putative 0.0764 0.1057 0.1057
Plasmodium vivax serine-repeat antigen (SERA) 0.0406 0.0551 0.2045
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0005 0.0005
Loa Loa (eye worm) trypsin family protein 0.0091 0.0104 0.0104
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0003 0.0003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Echinococcus granulosus cathepsin L 0.0764 0.1057 0.1057
Echinococcus multilocularis cathepsin L cysteine protease 0.129 0.1801 0.1801
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.192 0.2693 0.7753
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0091 0.0104 0.0104
Trypanosoma brucei I/6 autoantigen 0.0306 0.0408 0.1175
Trypanosoma brucei calpain-like protein, putative 0.192 0.2693 0.7753
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0036 0.0133
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0141 0.0174 0.0174
Brugia malayi cathepsin Z-like cysteine proteinase 0.0406 0.0551 0.0551
Toxoplasma gondii hypothetical protein 0.0553 0.0758 0.2182
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0001 0.0001
Schistosoma mansoni cathepsin F (C01 family) 0.0932 0.1294 0.1294
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0035 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0406 0.0551 0.0551
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0406 0.0551 0.0551
Echinococcus granulosus importin subunit beta 1 0.0033 0.0022 0.0022
Plasmodium vivax vivapain-2 0.129 0.1801 0.6689
Entamoeba histolytica hypothetical protein 0.0406 0.0551 0.2882
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0089 0.0101 0.1046
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0018 0.0002 0.0004
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0306 0.0408 0.1175
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0074 0.0074
Brugia malayi Cathepsin L-like precursor 0.129 0.1801 0.1801
Echinococcus multilocularis expressed protein 0.0798 0.1105 0.1105
Echinococcus granulosus peroxidasin 0.0065 0.0067 0.0067
Giardia lamblia Cathepsin L-like protease 0.0406 0.0551 0.1585
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0386 0.0522 0.0522
Brugia malayi calpain D 0.0553 0.0758 0.0758
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0033 0.0033
Leishmania major calmodulin, putative 0.0306 0.0408 0.1175
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0553 0.0758 0.2182
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0406 0.0551 0.3057
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0008 0.0008
Echinococcus multilocularis calpain 0.192 0.2693 0.2693
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0606 0.0833 0.0833
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Echinococcus multilocularis Transglutaminase 0.0035 0.0025 0.0025
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.1294 0.3726
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0032 0.0154
Onchocerca volvulus 0.0027 0.0013 0.003
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.7082 1 1
Echinococcus multilocularis endothelin converting enzyme 1 0.0094 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.0266 0.0765
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0006 0.0006
Leishmania major cytochrome p450-like protein 0.0034 0.0023 0.0067
Echinococcus multilocularis cathepsin L 0.0764 0.1057 0.1057
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0698 0.0964 0.0964
Plasmodium vivax plasmepsin V, putative 0.0018 0.0002 0.0006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0003 0.0017
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0033 0.0033
Giardia lamblia Programmed cell death protein-like protein 0.0027 0.0013 0.0039
Echinococcus multilocularis centrin 2 0.0306 0.0408 0.0408
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0032 0.0154
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Giardia lamblia Cathepsin B precursor 0.2471 0.3473 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0076 0.0076
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0006 0.0014
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0003 0.0009
Trypanosoma cruzi centrin, putative 0.0333 0.0446 0.0446
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0073 0.0073
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0033 0.0033
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0033 0.0033
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0046 0.0041 0.0041
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0005 0.0025
Toxoplasma gondii cathepsin CPC1 0.0406 0.0551 0.1585
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Entamoeba histolytica hypothetical protein 0.0041 0.0033 0.0175
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0043 0.0043
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0406 0.0551 0.0551
Echinococcus granulosus calpain 7 C02 family 0.192 0.2693 0.2693
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0023 0.0023
Plasmodium vivax aspartyl proteinase, putative 0.0018 0.0002 0.0006
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0003 0.0009
Giardia lamblia Hypothetical protein 0.031 0.0414 0.1193
Schistosoma mansoni peroxidasin 0.0065 0.0067 0.0067
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0406 0.0551 0.1585
Loa Loa (eye worm) hypothetical protein 0.0091 0.0104 0.0104
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0298 0.0397 0.0397
Trichomonas vaginalis calcium binding protein, putative 0.0306 0.0408 0.1175
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0006 0.0006
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0011 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0033 0.0096
Loa Loa (eye worm) blistered cuticle protein 3 0.0065 0.0067 0.0067
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0089 0.0101 0.0528
Schistosoma mansoni cathepsin B (C01 family) 0.0406 0.0551 0.0551
Echinococcus granulosus proteasome prosome macropain 0.0089 0.0101 0.0101
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Trichomonas vaginalis centrin, putative 0.0027 0.0013 0.0039
Brugia malayi cathepsin F-like cysteine proteinase 0.0406 0.0551 0.0551
Giardia lamblia Cathepsin L precursor 0.0406 0.0551 0.1585
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0048 0.0043 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Trypanosoma brucei Calpain-like protein 1.1 0.0553 0.0758 0.2182
Leishmania major kinesin, putative 0.1367 0.191 0.55
Brugia malayi Cell death protein 3 precursor 0.0151 0.0189 0.0189
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Onchocerca volvulus 0.004 0.0032 0.0071
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0023 0.0023
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0406 0.0551 0.2045
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0205 0.0266 0.1392
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0606 0.0833 0.2399
Brugia malayi Cathepsin L-like precursor 0.129 0.1801 0.1801
Toxoplasma gondii aldehyde dehydrogenase 0.0132 0.0162 0.0467
Giardia lamblia Cathepsin B precursor 0.0406 0.0551 0.1585
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0036 0.0036
Echinococcus granulosus tumor protein p63 0.0361 0.0487 0.0487
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0006 0.0006
Giardia lamblia Cathepsin L-like protease 0.0406 0.0551 0.1585
Echinococcus multilocularis apoptotic protease activating factor 1 0.0134 0.0165 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0033 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0006 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0113 0.0113
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Schistosoma mansoni cpg binding protein 0.0032 0.002 0.002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0006 0.0006
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0306 0.0408 0.1175
Echinococcus multilocularis snurportin 1 0.0353 0.0476 0.0476
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0406 0.0551 0.1585
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0021 0.0005 0.0005
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0011 0.0032
Brugia malayi Papain family cysteine protease containing protein 0.0764 0.1057 0.1057
Leishmania major hypothetical protein, conserved 0.0306 0.0408 0.1175
Plasmodium falciparum serine repeat antigen 9 0.0406 0.0551 0.3057
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Brugia malayi Papain family cysteine protease containing protein 0.0406 0.0551 0.0551
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0655 0.0903 0.0903
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0606 0.0833 0.2399
Echinococcus multilocularis calcium uptake protein 1 0.031 0.0414 0.0414
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0162 0.1682
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0061 0.0175
Brugia malayi Papain family cysteine protease containing protein 0.0764 0.1057 0.1057
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0033 0.0033
Plasmodium falciparum plasmepsin VI 0.0018 0.0002 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0033 0.0096
Onchocerca volvulus 0.0091 0.0104 0.023
Entamoeba histolytica calmodulin, putative 0.0306 0.0408 0.2136
Schistosoma mansoni hypothetical protein 0.0553 0.0758 0.0758
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0406 0.0551 0.1585
Giardia lamblia Alanyl dipeptidyl peptidase 0.0205 0.0266 0.0765
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0033 0.0033
Brugia malayi Pre-SET motif family protein 0.0655 0.0903 0.0903
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0406 0.0551 0.1585
Brugia malayi Probable myosin regulatory light chain 0.0032 0.002 0.002
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0089 0.0101 0.0101
Toxoplasma gondii aspartyl protease ASP1 0.0018 0.0002 0.0004
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0006 0.0006
Brugia malayi hypothetical protein 0.0134 0.0165 0.0165
Echinococcus granulosus EF hand domain containing family member A2 0.031 0.0414 0.0414
Brugia malayi prolyl oligopeptidase family protein 0.1713 0.24 0.24
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0032 0.0154
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.7082 1 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.129 0.1801 0.1801
Echinococcus granulosus cathepsin L cysteine proteinase 0.129 0.1801 0.1801
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0205 0.0266 0.0266
Schistosoma mansoni cpg binding protein 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.007 0.0074 0.0074
Mycobacterium ulcerans beta-lactamase 0.004 0.0032 0.0336
Loa Loa (eye worm) hypothetical protein 0.0094 0.0109 0.0109
Leishmania major phospholipase c-like protein 0.0306 0.0408 0.1175
Trypanosoma brucei prolyl endopeptidase 0.1713 0.24 0.6912
Loa Loa (eye worm) hypothetical protein 0.0553 0.0758 0.0758
Echinococcus granulosus dnaJ subfamily B 0.0427 0.058 0.058
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0089 0.0101 0.029
Schistosoma mansoni centrin 0.0306 0.0408 0.0408
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0036 0.0103
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0129 0.0129
Giardia lamblia Cathepsin L precursor 0.0406 0.0551 0.1585
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0067 0.0067
Brugia malayi beta-lactamase family protein 0.004 0.0032 0.0032
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0006 0.0006
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0013 0.0038
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0032 0.0336
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0018 0.0002 0.0004
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0178 0.0227 0.0227
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.0008 0.0008
Loa Loa (eye worm) prolyl oligopeptidase 0.0205 0.0266 0.0266
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0006 0.0006
Plasmodium vivax aspartyl proteinase, putative 0.0018 0.0002 0.0006
Leishmania major cathepsin L-like protease 0.139 0.1943 0.5596
Brugia malayi Protein kinase domain containing protein 0.0023 0.0008 0.0008
Mycobacterium tuberculosis Conserved protein 0.004 0.0032 0.0154
Entamoeba histolytica cysteine proteinase 1, putative 0.0764 0.1057 0.5536
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.5146 0.726 0.726
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0306 0.0408 0.1175
Echinococcus granulosus calcyphosin protein 0.0027 0.0013 0.0013
Giardia lamblia Cathepsin L precursor 0.0406 0.0551 0.1585
Echinococcus multilocularis programmed cell death protein 0.0333 0.0446 0.0446
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0606 0.0833 0.2399
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0406 0.0551 0.0551
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0406 0.0551 0.0551
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Leishmania major i/6 autoantigen-like protein 0.0306 0.0408 0.1175
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0005 0.0025
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.031 0.0414 0.1193
Echinococcus granulosus cathepsin b 0.7082 1 1
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0606 0.0833 0.2399
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0032 0.0093
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0073 0.0381
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0022 0.0064
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0553 0.0758 0.2182
Brugia malayi prolyl oligopeptidase family protein 0.0537 0.0735 0.0735
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0698 0.0964 1
Echinococcus granulosus expressed protein 0.0798 0.1105 0.1105
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0406 0.0551 0.1585
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Loa Loa (eye worm) glycogen phosphorylase 0.0108 0.0129 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0764 0.1057 0.3045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0406 0.0551 0.1585
Brugia malayi Papain family cysteine protease containing protein 0.0406 0.0551 0.0551
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0003 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0406 0.0551 0.1585
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0386 0.0522 0.0522
Brugia malayi fibroinase precursor 0.0406 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0141 0.0174 0.0174
Echinococcus granulosus cysteine protease 0.0764 0.1057 0.1057
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0047 0.0042 0.0432
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0537 0.0735 0.1618
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0033
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0306 0.0408 0.0408
Schistosoma mansoni calmodulin-related 0.0027 0.0013 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Echinococcus multilocularis calpain 7 (C02 family) 0.192 0.2693 0.2693
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0006 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0006 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0025 0.0118
Trypanosoma cruzi centrin-3 0.0333 0.0446 0.0446
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0006 0.0006
Brugia malayi PXA domain containing protein 0.0041 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0057 0.0056 0.0056
Trichomonas vaginalis centrin, putative 0.0027 0.0013 0.0039
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0023 0.0242
Brugia malayi proteasome subunit beta type 2 0.0043 0.0036 0.0036
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0021 0.0005 0.0005
Giardia lamblia Hypothetical protein 0.0406 0.0551 0.1585
Brugia malayi Peptidase family M13 containing protein 0.0094 0.0109 0.0109
Trypanosoma brucei kinesin, putative 0.1367 0.191 0.55
Toxoplasma gondii preprocathepsin c precursor, putative 0.0406 0.0551 0.1585
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0033 0.0033
Trichomonas vaginalis calcium binding protein, putative 0.0306 0.0408 0.1175
Onchocerca volvulus 0.0406 0.0551 0.1212
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0003 0.0003
Echinococcus granulosus EF HAND 1 calcium binding site 0.0306 0.0408 0.0408
Plasmodium vivax proteasome subunit beta type-5, putative 0.0089 0.0101 0.0375
Leishmania major hypothetical protein, unknown function 0.0553 0.0758 0.2182
Loa Loa (eye worm) papain family cysteine protease containing protein 0.129 0.1801 0.1801
Loa Loa (eye worm) hypothetical protein 0.0071 0.0076 0.0076
Brugia malayi Thioredoxin family protein 0.0035 0.0025 0.0025
Brugia malayi aspartic protease BmAsp-1, identical 0.0018 0.0002 0.0002
Schistosoma mansoni centrin-related 0.0306 0.0408 0.0408
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0021 0.0005 0.0005
Onchocerca volvulus Cathepsin L homolog 0.129 0.1801 0.3964
Trichomonas vaginalis centrin, putative 0.0306 0.0408 0.1175
Leishmania major cysteine peptidase A (CPA) 0.129 0.1801 0.5185
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Entamoeba histolytica calpain large subunit domain III containing protein 0.1367 0.191 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0406 0.0551 0.1585
Trypanosoma cruzi oligopeptidase b 0.0698 0.0964 0.0964
Loa Loa (eye worm) hypothetical protein 0.004 0.0032 0.0032
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0042 0.0042
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Schistosoma mansoni calpain C (C02 family) 0.192 0.2693 0.2693
Entamoeba histolytica calpain family cysteine protease, putative 0.0553 0.0758 0.3967
Schistosoma mansoni neprilysin-2 (M13 family) 0.0048 0.0043 0.0043
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0205 0.0266 0.1392
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0073 0.021
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0306 0.0408 0.0408
Brugia malayi PXA domain containing protein 0.0041 0.0033 0.0033
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0006 0.0006
Brugia malayi Importin beta-1 subunit 0.0033 0.0022 0.0022
Plasmodium vivax vivapain-1 0.0764 0.1057 0.3927
Trichomonas vaginalis calpain, putative 0.0553 0.0758 0.2182
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0011 0.0011
Entamoeba histolytica protein kinase, putative 0.1367 0.191 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Echinococcus multilocularis calpain 5 0.192 0.2693 0.2693
Trypanosoma cruzi cysteine peptidase, putative 0.139 0.1943 0.1943
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Brugia malayi Pre-SET motif family protein 0.0095 0.0109 0.0109
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0006 0.0006
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.7753
Brugia malayi nuclear receptor NHR-88 0.0022 0.0006 0.0006
Toxoplasma gondii EFHC1, putative 0.0306 0.0408 0.1175
Loa Loa (eye worm) hypothetical protein 0.0094 0.0109 0.0109
Onchocerca volvulus 0.0746 0.1031 0.227
Loa Loa (eye worm) calpain 5 0.1367 0.191 0.191
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0091 0.0104 0.0104
Brugia malayi prolyl oligopeptidase family protein 0.0298 0.0397 0.0397
Plasmodium vivax GPI-anchor transamidase, putative 0.0141 0.0174 0.0648
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0021 0.0005 0.0013
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0141 0.0174 0.0502
Trypanosoma cruzi kinesin, putative 0.1367 0.191 0.191
Trypanosoma brucei Calpain-like protein 1.2 0.0553 0.0758 0.2182
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0113 0.0113
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0033 0.0033
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Giardia lamblia Cysteine protease 0.0406 0.0551 0.1585
Schistosoma mansoni hypothetical protein 0.0353 0.0476 0.0476
Onchocerca volvulus 0.004 0.0032 0.0071
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.0758 0.0758
Mycobacterium tuberculosis Conserved protein 0.004 0.0032 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.129 0.1801 0.5185
Plasmodium falciparum plasmepsin IV 0.0018 0.0002 0.0008
Brugia malayi Papain family cysteine protease containing protein 0.129 0.1801 0.1801
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0033 0.0096
Toxoplasma gondii cathepsin B 0.2471 0.3473 1
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0032 0.0093
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0005 0.0013
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0162 0.0162
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0033 0.0033
Echinococcus multilocularis caspase 2 0.0151 0.0189 0.0189
Brugia malayi hypothetical protein 0.0041 0.0033 0.0033
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0178 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Onchocerca volvulus 0.3227 0.4543 1
Onchocerca volvulus 0.0162 0.0204 0.0449
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0011 0.0032
Schistosoma mansoni flap endonuclease-1 0.0023 0.0008 0.0008
Mycobacterium tuberculosis Probable peptidase 0.0698 0.0964 0.4569
Brugia malayi gamma-secretase subunit aph-1 0.028 0.0372 0.0372
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0129 0.0674
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0025 0.0118
Giardia lamblia Thymus-specific serine protease precursor 0.0021 0.0005 0.0013
Trypanosoma cruzi cysteine peptidase, putative 0.0358 0.0482 0.0482
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.5452 0.7693 0.7693
Brugia malayi Calmodulin-like protein 0.0306 0.0408 0.0408
Leishmania major hypothetical protein, conserved 0.004 0.0032 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0406 0.0551 0.1585
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0033 0.0033
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0006 0.0006
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0021 0.0005 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0932 0.1294 0.6774
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0132 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0033
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1713 0.24 0.6912
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0406 0.0551 0.0551
Plasmodium falciparum plasmepsin I 0.0018 0.0002 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0406 0.0551 0.1585
Loa Loa (eye worm) hypothetical protein 0.0932 0.1294 0.1294
Loa Loa (eye worm) hypothetical protein 0.004 0.0032 0.0032
Schistosoma mansoni calmodulin related calcium binding protein 0.0306 0.0408 0.0408
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0036 0.0036
Plasmodium falciparum serine repeat antigen 7 0.0406 0.0551 0.3057
Trypanosoma cruzi major cysteine proteinase, putative 0.0507 0.0693 0.0693
Loa Loa (eye worm) hypothetical protein 0.0406 0.0551 0.0551
Brugia malayi calpain family protein 1 0.5146 0.726 0.726
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Toxoplasma gondii centrin family protein 0.0027 0.0013 0.0039
Trypanosoma brucei prolyl oligopeptidase, putative 0.0698 0.0964 0.2776
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Trypanosoma brucei calpain, putative 0.0553 0.0758 0.2182
Loa Loa (eye worm) hypothetical protein 0.0091 0.0104 0.0104
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0011 0.0041
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0032 0.0154
Plasmodium falciparum calpain 0.0553 0.0758 0.4207
Plasmodium falciparum plasmepsin VIII, putative 0.0018 0.0002 0.0008
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0406 0.0551 0.1585
Trichomonas vaginalis peptide N-glycanase, putative 0.0035 0.0025 0.0072
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0013 0.0038
Entamoeba histolytica prolyl oligopeptidase family protein 0.0205 0.0266 0.1392
Echinococcus multilocularis glycoprotein Antigen 5 0.0091 0.0104 0.0104
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1508 0.211 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0406 0.0551 0.1585
Schistosoma mansoni hemoglobinase (C13 family) 0.0606 0.0833 0.0833
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0067 0.0067
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0006 0.0006
Echinococcus granulosus Tolloid protein 1 0.0046 0.0041 0.0041
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.0758 0.0758
Toxoplasma gondii cathepsin CPC2 0.0406 0.0551 0.1585
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Schistosoma mansoni cathepsin D (A01 family) 0.0018 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.139 0.1943 0.5596
Echinococcus granulosus calpain 5 0.192 0.2693 0.2693
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Echinococcus multilocularis neurocalcin 0.0306 0.0408 0.0408
Trypanosoma cruzi cysteine proteinase, putative 0.0764 0.1057 0.1057
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0036 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0013
Toxoplasma gondii aspartyl protease ASP3 0.0018 0.0002 0.0004
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0033 0.0033
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0298 0.0397 0.1142
Trypanosoma brucei hypothetical protein, conserved 0.0306 0.0408 0.1175
Echinococcus granulosus snurportin 1 0.0353 0.0476 0.0476
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0306 0.0408 0.2136
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0406 0.0551 0.3057
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0073 0.0073
Leishmania major cathepsin L-like protease 0.129 0.1801 0.5185
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0141 0.0174 0.0502
Trypanosoma cruzi cruzipain precursor, putative 0.139 0.1943 0.1943
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1713 0.24 0.24
Brugia malayi Cytochrome P450 family protein 0.0034 0.0023 0.0023
Trypanosoma brucei Aph-1 protein, putative 0.0109 0.013 0.0374
Loa Loa (eye worm) calpain family protein 1 0.5146 0.726 0.726
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0032 0.0032
Brugia malayi carbohydrate phosphorylase 0.0108 0.0129 0.0129
Brugia malayi hypothetical protein 0.0162 0.0204 0.0204
Trypanosoma cruzi calmodulin, putative 0.0306 0.0408 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0006 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Loa Loa (eye worm) hypothetical protein 0.0205 0.0266 0.0266
Toxoplasma gondii calmodulin, putative 0.0027 0.0013 0.0039
Giardia lamblia Encystation-specific protease 0.0406 0.0551 0.1585
Echinococcus granulosus Calcium binding protein 0.0027 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0006 0.0006
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0406 0.0551 0.2882
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0006 0.0006
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0005 0.0013
Toxoplasma gondii hypothetical protein 0.0205 0.0266 0.0765
Echinococcus granulosus microtubule associated protein 2 0.1492 0.2088 0.2088
Giardia lamblia Cathepsin B precursor 0.0406 0.0551 0.1585
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0129 0.0129
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0013 0.0013
Echinococcus granulosus neuronal calcium sensor 0.0306 0.0408 0.0408
Brugia malayi RNA, U transporter 1 0.0094 0.0109 0.0109
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0023 0.0023
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0606 0.0833 0.2399
Leishmania major calmodulin-like protein 0.0306 0.0408 0.1175
Schistosoma mansoni hemoglobinase (C13 family) 0.0606 0.0833 0.0833
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0113 0.0113
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0006 0.0006
Onchocerca volvulus 0.0091 0.0104 0.023
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0205 0.0266 0.0765
Onchocerca volvulus 0.0027 0.0013 0.003
Entamoeba histolytica grainin, putative 0.031 0.0414 0.217
Onchocerca volvulus Chorion peroxidase homolog 0.0065 0.0067 0.0147
Echinococcus granulosus Glycosyl transferase family 35 0.0108 0.0129 0.0129
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Leishmania major hypothetical protein, conserved 0.0553 0.0758 0.2182
Brugia malayi cathepsin L-like cysteine proteinase 0.0406 0.0551 0.0551
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0033 0.0033
Toxoplasma gondii calmodulin CAM1 0.031 0.0414 0.1193
Schistosoma mansoni ap endonuclease 0.002 0.0003 0.0003
Echinococcus granulosus cathepsin l cysteine peptidase 0.129 0.1801 0.1801
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0306 0.0408 0.0408
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.011 0.011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0406 0.0551 0.1585
Loa Loa (eye worm) hypothetical protein 0.0091 0.0104 0.0104
Leishmania major hypothetical protein, conserved 0.0023 0.0008 0.0024
Leishmania major oligopeptidase b 0.0698 0.0964 0.2776
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0006 0.0006
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0406 0.0551 0.2045
Brugia malayi EF hand family protein 0.0306 0.0408 0.0408
Brugia malayi Trypsin family protein 0.0091 0.0104 0.0104
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Plasmodium falciparum cysteine proteinase falcipain 3 0.129 0.1801 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0036 0.0036
Echinococcus granulosus calcium uptake protein 1 0.031 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0406 0.0551 0.0551
Echinococcus granulosus cpg binding protein 0.0032 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0406 0.0551 0.0551
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0011 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0764 0.1057 0.3045
Loa Loa (eye worm) hypothetical protein 0.004 0.0032 0.0032
Echinococcus multilocularis cysteine protease 0.129 0.1801 0.1801
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0406 0.0551 0.2045
Plasmodium vivax importin-beta 2, putative 0.0033 0.0022 0.0082
Schistosoma mansoni memapsin-2 (A01 family) 0.0461 0.0627 0.0627
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0553 0.0758 0.2182
Loa Loa (eye worm) hypothetical protein 0.0162 0.0204 0.0204
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0073 0.0405
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0698 0.0964 0.2776
Loa Loa (eye worm) hypothetical protein 0.0053 0.005 0.005
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0406 0.0551 0.3057
Entamoeba histolytica hypothetical protein 0.0041 0.0033 0.0175
Loa Loa (eye worm) peptidase C13 family protein 0.0606 0.0833 0.0833
Loa Loa (eye worm) hypothetical protein 0.007 0.0074 0.0074
Trypanosoma brucei calpain, putative 0.0553 0.0758 0.2182
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Trichomonas vaginalis calcium binding protein, putative 0.0333 0.0446 0.1284
Loa Loa (eye worm) hypothetical protein 0.007 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0406 0.0551 0.1585
Giardia lamblia Cysteine protease 0.0406 0.0551 0.1585
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0406 0.0551 0.0551
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0032 0.0032
Onchocerca volvulus 0.129 0.1801 0.3964
Echinococcus granulosus transmembrane protease serine 3 0.0091 0.0104 0.0104
Plasmodium vivax SET domain protein, putative 0.0095 0.0109 0.0405
Plasmodium falciparum plasmepsin V 0.0018 0.0002 0.0008
Plasmodium vivax hypothetical protein, conserved 0.031 0.0414 0.1539
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Giardia lamblia Glycogen phosphorylase 0.0108 0.0129 0.0371
Schistosoma mansoni caspase-7 (C14 family) 0.0151 0.0189 0.0189
Trichomonas vaginalis calpain, putative 0.0553 0.0758 0.2182
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0132 0.0162 0.0162
Entamoeba histolytica cysteine protease, putative 0.0406 0.0551 0.2882
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0018 0.0002 0.0004
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0048 0.0043 0.0043
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0698 0.0964 1
Leishmania major cathepsin L-like protease 0.129 0.1801 0.5185
Plasmodium vivax plasmepsin IV, putative 0.0018 0.0002 0.0006
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0033 0.0033
Leishmania major importin beta-1 subunit, putative 0.0027 0.0013 0.0038
Echinococcus multilocularis calumenin 0.031 0.0414 0.0414
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Trichomonas vaginalis calmodulin, putative 0.031 0.0414 0.1193
Entamoeba histolytica cysteine protease, putative 0.0406 0.0551 0.2882
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.5452 0.7693 0.7693
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0205 0.0266 0.0765
Onchocerca volvulus 0.0053 0.005 0.011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.0758 0.0758
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1713 0.24 0.24
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0006 0.0006
Echinococcus multilocularis proteasome (prosome, macropain) 0.0089 0.0101 0.0101
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0178 0.0227 0.0227
Schistosoma mansoni neuronal calcium sensor 0.0306 0.0408 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0006 0.0006
Loa Loa (eye worm) transcription factor SMAD2 0.0137 0.0169 0.0169
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0067 0.0147
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0033 0.0033
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0306 0.0408 0.0408
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0104 0.0104
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2471 0.3473 0.3473
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0033 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0033 0.0033
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0764 0.1057 0.1057
Echinococcus granulosus neurocalcin 0.0306 0.0408 0.0408
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Loa Loa (eye worm) hypothetical protein 0.4594 0.6478 0.6478
Echinococcus granulosus programmed cell death protein 0.0333 0.0446 0.0446
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0033 0.0033
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0032 0.0093
Trypanosoma cruzi Aph-1 protein, putative 0.0109 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0071 0.0076 0.0076
Echinococcus granulosus calpain A 0.192 0.2693 0.2693
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Schistosoma mansoni importin beta-1 0.0033 0.0022 0.0022
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0006 0.0006
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.7753
Brugia malayi cathepsin F-like cysteine proteinase 0.0358 0.0482 0.0482
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0033 0.0096
Echinococcus granulosus cathepsin b 0.7082 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.139 0.1943 0.1943
Onchocerca volvulus 0.0178 0.0227 0.0499
Brugia malayi Myosin regulatory light chain 1 0.0027 0.0013 0.0013
Plasmodium falciparum serine repeat antigen 4 0.0406 0.0551 0.3057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0094 0.0109 0.0109
Echinococcus multilocularis cathepsin L 0.0406 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Leishmania major calpain protease-like protein 0.0553 0.0758 0.2182
Schistosoma mansoni cathepsin S (C01 family) 0.0406 0.0551 0.0551
Echinococcus granulosus enteropeptidase 0.0091 0.0104 0.0104
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Trypanosoma brucei Calpain-like protein 2 0.0553 0.0758 0.2182
Brugia malayi peptidase family M13 containing protein 0.0023 0.0008 0.0008
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0306 0.0408 0.0408
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0032 0.0336
Brugia malayi ecdysteroid receptor 0.0022 0.0006 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0113 0.0113
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0094 0.0109 0.0109
Entamoeba histolytica cysteine proteinase, putative 0.0764 0.1057 0.5536
Trichomonas vaginalis calcineurin B subunit, putative 0.0306 0.0408 0.1175
Trypanosoma cruzi I/6 autoantigen, putative 0.0306 0.0408 0.0408
Leishmania major centrin, putative 0.0306 0.0408 0.1175
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0141 0.0174 0.0174
Trypanosoma cruzi oligopeptidase b 0.0698 0.0964 0.0964
Schistosoma mansoni calmodulin 0.0306 0.0408 0.0408
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0073 0.0271
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0306 0.0408 0.1175
Echinococcus granulosus inhibitor of apoptosis protein 0.0178 0.0227 0.0227
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0129 0.0129
Onchocerca volvulus 0.0091 0.0104 0.023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Plasmodium falciparum serine repeat antigen 2 0.0406 0.0551 0.3057
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0104 0.0104
Brugia malayi Pepsin A precursor 0.0018 0.0002 0.0002
Echinococcus multilocularis prolyl endopeptidase 0.1713 0.24 0.24
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0406 0.0551 0.0551
Trypanosoma brucei mitochondrial calcium uptake 1 0.0306 0.0408 0.1175
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Onchocerca volvulus Legumain homolog 0.0606 0.0833 0.1834
Mycobacterium ulcerans transglutaminase family protein 0.0035 0.0025 0.0259
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0306 0.0408 0.0408
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0553 0.0758 0.2182
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0537 0.0735 0.0735
Toxoplasma gondii aspartyl protease 0.0018 0.0002 0.0004
Echinococcus multilocularis programmed cell death protein 0.0333 0.0446 0.0446
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0089 0.0101 0.029
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.0008 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0162 0.1682
Mycobacterium leprae probable zinc metalloprotease 0.0094 0.0109 0.1129
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0033 0.0033
Echinococcus multilocularis calpain family protein 1, d 0.3779 0.5325 0.5325
Giardia lamblia Cathepsin B precursor 0.0406 0.0551 0.1585
Trichomonas vaginalis calmodulin, putative 0.0306 0.0408 0.1175
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0113 0.0113
Trypanosoma brucei calpain-like protein, putative 0.192 0.2693 0.7753
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0109 0.0109
Trypanosoma brucei oligopeptidase b 0.0698 0.0964 0.2776
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.7082 1 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0406 0.0551 0.2882
Plasmodium vivax unspecified product 0.0764 0.1057 0.3927
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Brugia malayi nuclear hormone receptor 0.0022 0.0006 0.0006
Trypanosoma cruzi Aph-1 protein, putative 0.0109 0.013 0.013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Schistosoma mansoni neprilysin 0.0025 0.001 0.001
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0027 0.0013 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.2693
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Echinococcus multilocularis GPCR, family 2 0.0018 0.0001 0.0001
Echinococcus granulosus EF hand domain containing family member A2 0.0306 0.0408 0.0408
Onchocerca volvulus Cell death protein 3 homolog 0.0151 0.0189 0.0417
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0606 0.0833 0.2399
Echinococcus multilocularis calcyphosin protein 0.0027 0.0013 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.192 0.2693 0.2693
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0091 0.0104 0.0104
Toxoplasma gondii calcium-dependent protein kinase 0.031 0.0414 0.1193
Giardia lamblia Serine peptidase, putative 0.0021 0.0005 0.0013
Brugia malayi Cathepsin L-like precursor 0.129 0.1801 0.1801
Trypanosoma cruzi prolyl endopeptidase 0.1713 0.24 0.24
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0764 0.1057 0.5536
Giardia lamblia Cysteine protease 0.0406 0.0551 0.1585
Brugia malayi Proteasome A-type and B-type family protein 0.0089 0.0101 0.0101
Onchocerca volvulus 0.0022 0.0006 0.0014
Brugia malayi Cathepsin L-like cysteine proteinase 0.0932 0.1294 0.1294
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0132 0.0162 0.0769
Loa Loa (eye worm) calpain 0.192 0.2693 0.2693
Mycobacterium tuberculosis Conserved protein 0.0035 0.0025 0.0118
Plasmodium falciparum serine repeat antigen 8 0.0406 0.0551 0.3057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Echinococcus granulosus centrin 2 0.0306 0.0408 0.0408
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0006 0.0006
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0033 0.0033
Trypanosoma cruzi kinesin, putative 0.1367 0.191 0.191
Onchocerca volvulus 0.0065 0.0067 0.0147
Echinococcus multilocularis cathepsin l cysteine peptidase 0.129 0.1801 0.1801
Brugia malayi cathepsin Z-like cysteine proteinase 0.0406 0.0551 0.0551
Toxoplasma gondii troponin c, isotype gamma, putative 0.0306 0.0408 0.1175
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0005 0.0005
Plasmodium vivax aspartyl protease, putative 0.0018 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0008
Schistosoma mansoni peroxidasin 0.0065 0.0067 0.0067
Echinococcus granulosus GPI anchor transamidase 0.0141 0.0174 0.0174
Echinococcus multilocularis Myosin regulatory light chain 0.0027 0.0013 0.0013
Onchocerca volvulus 0.0021 0.0005 0.001
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0032 0.0093
Schistosoma mansoni cathepsin C 0.0406 0.0551 0.0551
Brugia malayi calpain 5 0.0553 0.0758 0.0758
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.0758 0.0758
Plasmodium falciparum serine repeat antigen 6 0.0406 0.0551 0.3057
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0033 0.0033
Entamoeba histolytica cysteine proteinase 2 0.0764 0.1057 0.5536
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0042 0.0218
Trypanosoma brucei centrin-3 0.0333 0.0446 0.1284
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0067 0.0067
Schistosoma mansoni rab 0.0306 0.0408 0.0408
Onchocerca volvulus 0.0095 0.0109 0.024
Echinococcus granulosus glycoprotein Antigen 5 0.0091 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0033 0.0033
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0003 0.0009
Brugia malayi cathepsin L-like precursor 0.0932 0.1294 0.1294
Loa Loa (eye worm) hypothetical protein 0.004 0.0032 0.0032
Trichomonas vaginalis calmodulin, putative 0.0306 0.0408 0.1175
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.7082 1 1
Trichomonas vaginalis calmodulin-2, putative 0.0306 0.0408 0.1175
Brugia malayi Kringle domain containing protein 0.0023 0.0008 0.0008
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0073 0.0073
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Giardia lamblia Hypothetical protein 0.0035 0.0025 0.0072
Brugia malayi cathepsin L precursor 0.0406 0.0551 0.0551
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0013 0.0013
Echinococcus multilocularis programmed cell death protein 6 0.0032 0.002 0.002
Plasmodium vivax hypothetical protein, conserved 0.004 0.0032 0.012
Leishmania major cathepsin L-like protease 0.139 0.1943 0.5596
Brugia malayi Trypsin family protein 0.0091 0.0104 0.0104
Trichomonas vaginalis calpain, putative 0.0553 0.0758 0.2182
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0005 0.0005
Echinococcus granulosus apoptotic protease activating factor 1 0.0134 0.0165 0.0165
Schistosoma mansoni calpain (C02 family) 0.192 0.2693 0.2693
Entamoeba histolytica prolyl oligopeptidase family protein 0.0205 0.0266 0.1392
Onchocerca volvulus 0.0035 0.0025 0.0055
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0091 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0932 0.1294 0.1294
Brugia malayi prolyl oligopeptidase family protein 0.0205 0.0266 0.0266
Trichomonas vaginalis centrin, putative 0.0306 0.0408 0.1175
Onchocerca volvulus 0.004 0.0032 0.0071
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.0758 0.0758
Brugia malayi hypothetical protein 0.0065 0.0067 0.0067
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.011 0.011
Trypanosoma brucei caltractin, putative 0.0333 0.0446 0.1284
Schistosoma mansoni hypothetical protein 0.0052 0.0049 0.0049
Plasmodium falciparum flap endonuclease 1 0.0025 0.0011 0.0062
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0056 0.0056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0932 0.1294 0.1294
Plasmodium vivax vivapain-2 0.129 0.1801 0.6689
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0006 0.0006
Trichomonas vaginalis caltractin, putative 0.0027 0.0013 0.0039
Entamoeba histolytica cysteine protease, putative 0.0406 0.0551 0.2882
Loa Loa (eye worm) hypothetical protein 0.0134 0.0165 0.0165
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0406 0.0551 0.0551
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0006 0.0006
Onchocerca volvulus 0.0018 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0031 0.0031
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0023 0.0023
Entamoeba histolytica calcium-binding protein, putative 0.0306 0.0408 0.2136
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Onchocerca volvulus Peroxidase homolog 0.0065 0.0067 0.0147
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0003 0.0012
Giardia lamblia Cathepsin B precursor 0.0406 0.0551 0.1585
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0033 0.0033
Entamoeba histolytica cysteine protease, putative 0.129 0.1801 0.9428
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0032 0.0154
Trypanosoma cruzi calmodulin, putative 0.0306 0.0408 0.0408
Brugia malayi Cathepsin L-like precursor 0.129 0.1801 0.1801
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0011 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Onchocerca volvulus 0.0091 0.0104 0.023
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0018 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0033 0.0033
Trypanosoma brucei centrin, putative 0.0306 0.0408 0.1175
Onchocerca volvulus 0.0091 0.0104 0.023
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.192 0.2693 0.2693
Onchocerca volvulus 0.0065 0.0067 0.0147
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0103 0.0103
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0134 0.0165 0.0165
Leishmania major calcineurin B subunit, putative 0.0306 0.0408 0.1175
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0141 0.0174 0.0502
Toxoplasma gondii prolyl endopeptidase 0.1713 0.24 0.6912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.129 0.1801 0.5185
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Entamoeba histolytica GPI-anchor transamidase, putative 0.0141 0.0174 0.0913
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Entamoeba histolytica cysteine proteinase, putative 0.129 0.1801 0.9428
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0306 0.0408 0.2136
Mycobacterium ulcerans hypothetical protein 0.004 0.0032 0.0336
Brugia malayi MH2 domain containing protein 0.0137 0.0169 0.0169
Entamoeba histolytica cysteine protease, putative 0.0406 0.0551 0.2882
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Loa Loa (eye worm) hypothetical protein 0.0178 0.0227 0.0227
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0205 0.0266 0.0765
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0306 0.0408 0.0408
Schistosoma mansoni neuronal calcium sensor 0.0306 0.0408 0.0408
Schistosoma mansoni cathepsin F (C01 family) 0.129 0.1801 0.1801
Giardia lamblia Cathepsin B precursor 0.2471 0.3473 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.192 0.2693 0.2693
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0055 0.0055
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0036 0.0036
Onchocerca volvulus 0.0065 0.0067 0.0147
Plasmodium falciparum peptidase, putative 0.0205 0.0266 0.1476
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0178 0.0227 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0006 0.0006
Mycobacterium leprae Probable lipase LipE 0.004 0.0032 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Brugia malayi calcium-binding protein 0.0306 0.0408 0.0408
Entamoeba histolytica calmodulin, putative 0.0306 0.0408 0.2136
Trichomonas vaginalis calmodulin, putative 0.0306 0.0408 0.1175
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.0337 0.0337
Onchocerca volvulus 0.0052 0.0049 0.0108
Brugia malayi GPI-anchor transamidase 0.0141 0.0174 0.0174
Giardia lamblia Cathepsin L precursor 0.0406 0.0551 0.1585
Echinococcus multilocularis neuronal calcium sensor 0.0306 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0003 0.0009
Trypanosoma cruzi cysteine protease, putative 0.0764 0.1057 0.1057
Leishmania major proteasome beta 5 subunit, putative 0.0089 0.0101 0.029
Echinococcus multilocularis calpain A 0.5456 0.7699 0.7699
Trypanosoma cruzi cysteine peptidase, putative 0.139 0.1943 0.1943
Brugia malayi Cathepsin L-like precursor 0.0358 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.0091 0.0104 0.0104
Entamoeba histolytica cysteine proteinase, putative 0.129 0.1801 0.9428
Toxoplasma gondii exonuclease III APE 0.002 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Onchocerca volvulus 0.129 0.1801 0.3964
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0109 0.0314
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0042 0.0218
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0067 0.0067
Entamoeba histolytica prolyl oligopeptidase family protein 0.0205 0.0266 0.1392
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0141 0.0174 0.0502
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0006 0.0014
Brugia malayi Trypsin family protein 0.0091 0.0104 0.0104
Trypanosoma brucei calmodulin, putative 0.0306 0.0408 0.1175
Entamoeba histolytica hypothetical protein, conserved 0.0205 0.0266 0.1392
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Trichomonas vaginalis calcium binding proteins, putative 0.0306 0.0408 0.1175
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0406 0.0551 0.0551
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0553 0.0758 0.2182
Giardia lamblia Cathepsin B precursor 0.2471 0.3473 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0049 0.0049
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0104 0.0104
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0032 0.0032
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0306 0.0408 0.0408
Echinococcus granulosus cathepsin L 0.0406 0.0551 0.0551
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0032 0.0032
Echinococcus multilocularis enteropeptidase 0.0091 0.0104 0.0104
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0006 0.0006
Onchocerca volvulus Prolyl endopeptidase homolog 0.1713 0.24 0.5284
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0091 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0039 0.0031 0.0031
Trypanosoma brucei cysteine peptidase C (CPC) 0.2471 0.3473 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.2693
Giardia lamblia Hypothetical protein 0.0406 0.0551 0.1585
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0104 0.0104
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0003 0.0032
Loa Loa (eye worm) myosin regulatory light chain 1 0.0027 0.0013 0.0013
Echinococcus multilocularis cathepsin b 0.7082 1 1
Trichomonas vaginalis kakapo, putative 0.0027 0.0013 0.0039
Trichomonas vaginalis calmodulin, putative 0.0333 0.0446 0.1284
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0018 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.129 0.1801 0.5185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Loa Loa (eye worm) hypothetical protein 0.0205 0.0266 0.0266
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0386 0.0522 0.0522
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0764 0.1057 0.1057
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0011 0.0058
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0006 0.0006
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0067 0.0147
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0027 0.0013 0.005
Entamoeba histolytica calcium binding family protein 0.0306 0.0408 0.2136
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0089 0.0101 0.0478
Brugia malayi RasGEF domain containing protein 0.0027 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0266 0.0266
Loa Loa (eye worm) ctsf protein 0.129 0.1801 0.1801
Onchocerca volvulus Dual oxidase homolog 0.0065 0.0067 0.0147
Loa Loa (eye worm) hypothetical protein 0.0071 0.0076 0.0076
Echinococcus granulosus Myosin regulatory light chain 0.0027 0.0013 0.0013
Brugia malayi Cathepsin L-like precursor 0.129 0.1801 0.1801
Echinococcus granulosus cathepsin L cysteine protease 0.0764 0.1057 0.1057
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0205 0.0266 0.0266
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0406 0.0551 0.0551
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.2182
Onchocerca volvulus 0.0306 0.0408 0.0898
Giardia lamblia Calmodulin 0.0027 0.0013 0.0039
Loa Loa (eye worm) programmed cell death protein 6 0.031 0.0414 0.0414
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0036 0.0103
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0008 0.0008
Trichomonas vaginalis calmodulin, putative 0.0306 0.0408 0.1175
Schistosoma mansoni gamma-secretase subunit aph-1 0.028 0.0372 0.0372
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0553 0.0758 0.2182
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0698 0.0964 0.4569
Plasmodium falciparum cysteine proteinase falcipain 1 0.0764 0.1057 0.5872
Onchocerca volvulus 0.0023 0.0008 0.0018
Onchocerca volvulus 0.129 0.1801 0.3964
Leishmania major centrin, putative 0.0306 0.0408 0.1175
Echinococcus multilocularis Tolloid protein 1 0.0046 0.0041 0.0041
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1032 0.1436 0.1436
Schistosoma mansoni cercarial elastase (S01 family) 0.0091 0.0104 0.0104
Plasmodium falciparum serine repeat antigen 3 0.0406 0.0551 0.3057
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Brugia malayi programmed cell death protein 6 0.0306 0.0408 0.0408
Echinococcus multilocularis transmembrane protease serine 3 0.0091 0.0104 0.0104
Trichomonas vaginalis calmodulin, putative 0.0306 0.0408 0.1175
Onchocerca volvulus 0.0091 0.0104 0.023
Onchocerca volvulus Glycogen phosphorylase homolog 0.0108 0.0129 0.0284
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0764 0.1057 0.3045
Echinococcus multilocularis GPI anchor transamidase 0.0141 0.0174 0.0174
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0826 0.1144 0.1144
Brugia malayi Trypsin-like protease protein 5 0.0091 0.0104 0.0104
Echinococcus multilocularis Glycosyl transferase, family 35 0.0108 0.0129 0.0129
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0067 0.0067
Brugia malayi beta-lactamase family protein 0.004 0.0032 0.0032
Trichomonas vaginalis calmodulin, putative 0.0027 0.0013 0.0039
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0008 0.0008
Plasmodium falciparum centrin-4 0.0027 0.0013 0.0075
Schistosoma mansoni reticulocalbin 0.0306 0.0408 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0406 0.0551 0.1585
Trypanosoma cruzi cruzipain precursor, putative 0.0358 0.0482 0.0482
Plasmodium falciparum serine repeat antigen 1 0.0406 0.0551 0.3057
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0095 0.0109 0.0109
Brugia malayi hypothetical protein 0.0041 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.129 0.1801 0.5185
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.0008 0.0031
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0033 0.0033
Brugia malayi Neuronal calcium sensor family protein 1 0.0027 0.0013 0.0013
Schistosoma mansoni coup transcription factor 0.0022 0.0006 0.0006
Schistosoma mansoni inhibitor of apoptosis protein 0.0178 0.0227 0.0227
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.2471 0.3473 1
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0073 0.021
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0553 0.0758 0.2182
Plasmodium vivax aspartyl protease, putative 0.0018 0.0002 0.0006
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.192 0.2693 0.2693
Echinococcus granulosus calpain A 0.5456 0.7699 0.7699
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0353 0.0476 0.0476
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0553 0.0758 0.2182
Schistosoma mansoni cathepsin D (A01 family) 0.0018 0.0002 0.0002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0001 0.0001
Trichomonas vaginalis centrin, putative 0.0027 0.0013 0.0039
Loa Loa (eye worm) calpain D 0.0553 0.0758 0.0758
Echinococcus granulosus cathepsin l1 0.0932 0.1294 0.1294
Onchocerca volvulus 0.031 0.0414 0.0912
Loa Loa (eye worm) hypothetical protein 0.0358 0.0482 0.0482
Entamoeba histolytica hypothetical protein 0.0041 0.0033 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0033 0.0033
Entamoeba histolytica grainin 2 0.0027 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0091 0.0104 0.0104
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2471 0.3473 0.3473
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0406 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0033
Echinococcus multilocularis cathepsin b 0.7082 1 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0003 1
Echinococcus granulosus gamma secretase subunit aph 1 0.028 0.0372 0.0372
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.7082 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0406 0.0551 0.1585
Loa Loa (eye worm) hypothetical protein 0.129 0.1801 0.1801
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Schistosoma mansoni myosin light chain 0.0027 0.0013 0.0013
Mycobacterium tuberculosis Long conserved protein 0.0035 0.0025 0.0118
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0023 0.0067
Mycobacterium ulcerans hypothetical protein 0.0091 0.0104 0.1083
Trypanosoma brucei centrin, putative 0.0306 0.0408 0.1175
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0537 0.0735 0.0735
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0073 0.021
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0553 0.0758 0.2182
Leishmania major cathepsin L-like protease 0.129 0.1801 0.5185
Toxoplasma gondii cathepsin CPL 0.129 0.1801 0.5185
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0067 0.0067
Trichomonas vaginalis set domain proteins, putative 0.0746 0.1031 0.2968
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0092 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0358 0.0482 0.0482
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0406 0.0551 0.1585
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0046 0.0041 0.0041
Trichomonas vaginalis calmodulin, putative 0.0306 0.0408 0.1175
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0006 0.0006
Plasmodium vivax serine-repeat antigen (SERA) 0.0406 0.0551 0.2045
Leishmania major calmodulin, putative 0.0306 0.0408 0.1175
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0042 0.0218
Giardia lamblia Cysteine protease 0.0406 0.0551 0.1585
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0205 0.0266 0.0765
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0113 0.0113
Onchocerca volvulus 0.129 0.1801 0.3964
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0006 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0764 0.1057 0.5536
Mycobacterium ulcerans zinc metalloprotease 0.0094 0.0109 0.1129
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0306 0.0408 0.0408
Brugia malayi Cathepsin L-like precursor 0.0932 0.1294 0.1294
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0298 0.0397 0.1142
Loa Loa (eye worm) aspartyl protease 6 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0036 0.0036
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0306 0.0408 0.1515
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Schistosoma mansoni calcium binding atopy-related autoantigen 0.031 0.0414 0.0414
Echinococcus multilocularis hypothetical protein 0.192 0.2693 0.2693
Loa Loa (eye worm) hypothetical protein 0.0151 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0044 0.0038 0.0038
Trypanosoma brucei Component of motile flagella 41 0.0306 0.0408 0.1175
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0003 0.5
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0033 0.0033
Giardia lamblia Cathepsin L precursor 0.0406 0.0551 0.1585
Brugia malayi EF hand family protein 0.031 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0406 0.0551 0.0551
Schistosoma mansoni cathepsin F (C01 family) 0.129 0.1801 0.1801
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0073 0.021
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0073 0.0073
Loa Loa (eye worm) cysteine protease 0.129 0.1801 0.1801
Schistosoma mansoni ef hand domain family member A2 0.0306 0.0408 0.0408
Loa Loa (eye worm) beta-lactamase 0.004 0.0032 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0109 0.0109
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0036 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0006 0.0006
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0358 0.0482 0.0482
Brugia malayi steroid hormone receptor 0.0022 0.0006 0.0006
Schistosoma mansoni neuronal calcium sensor 0.0306 0.0408 0.0408
Schistosoma mansoni hypothetical protein 0.0465 0.0634 0.0634
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Echinococcus multilocularis calmodulin 0.0306 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.1713 0.24 0.24
Toxoplasma gondii EF hand domain-containing protein 0.0027 0.0013 0.0039
Trichomonas vaginalis calcium binding protein, putative 0.0306 0.0408 0.1175
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0162 0.0162
Onchocerca volvulus 0.003 0.0018 0.0039
Echinococcus multilocularis peroxidasin 0.0065 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.2471 0.3473 1
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0406 0.0551 0.2045
Echinococcus granulosus calpain 0.192 0.2693 0.2693
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0033 0.0033
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0032 0.0032
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0178 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0056 0.0056
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0406 0.0551 0.2045
Brugia malayi Trypsin family protein 0.0091 0.0104 0.0104
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0036 0.0103
Trypanosoma brucei Calpain-like protein CALP1.3 0.0553 0.0758 0.2182
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.192 0.2693 0.2693
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0006 0.0006
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0406 0.0551 0.1585
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0042 0.0198
Plasmodium falciparum plasmepsin IX 0.0018 0.0002 0.0008
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0129 0.0129
Trypanosoma cruzi I/6 autoantigen, putative 0.0306 0.0408 0.0408
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0036 0.0036
Onchocerca volvulus Peroxidase homolog 0.0065 0.0067 0.0147
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.001 0.001
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0033 0.0033
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0073 0.0073
Echinococcus granulosus calbindin 32 0.031 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Chlamydia trachomatis glycogen phosphorylase 0.0108 0.0129 0.5
Echinococcus multilocularis inhibitor of apoptosis protein 0.0178 0.0227 0.0227
Brugia malayi CXXC zinc finger family protein 0.003 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.129 0.1801 0.5185
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0113 0.0113
Brugia malayi Cathepsin L-like precursor 0.129 0.1801 0.1801
Toxoplasma gondii peptidase c13 family protein 0.0141 0.0174 0.0502
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0406 0.0551 0.2045
Schistosoma mansoni calpain-7 (C02 family) 0.1922 0.2697 0.2697
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0358 0.0482 0.0482
Mycobacterium tuberculosis Conserved protein 0.004 0.0032 0.0154
Echinococcus multilocularis EF hand domain containing family member A2 0.0306 0.0408 0.0408
Echinococcus granulosus Transglutaminase 0.0035 0.0025 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.007 0.007
Echinococcus multilocularis microtubule associated protein 2 0.1492 0.2088 0.2088
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0032 0.0032
Mycobacterium ulcerans putative transglutaminase-like protein 0.0035 0.0025 0.0259
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0033 0.0033
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0001 0.0001
Loa Loa (eye worm) fibroinase 0.129 0.1801 0.1801
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0032 0.0032
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0013 0.0038
Plasmodium falciparum plasmepsin III 0.0018 0.0002 0.0008
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0406 0.0551 0.2045
Echinococcus multilocularis calbindin 32 0.031 0.0414 0.0414
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0129 0.0371
Mycobacterium ulcerans lipase LipD 0.004 0.0032 0.0336
Trypanosoma cruzi major cysteine proteinase, putative 0.0406 0.0551 0.0551
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0033 0.0096
Echinococcus granulosus caspase 2 0.0151 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0067 0.0067
Plasmodium vivax hypothetical protein, conserved 0.0205 0.0266 0.0987
Schistosoma mansoni cpg binding protein 0.003 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0013
Echinococcus granulosus cathepsin l1 0.129 0.1801 0.1801
Brugia malayi calpain family protein 1 0.5146 0.726 0.726
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0006 0.0006
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0027 0.0013 0.003
Loa Loa (eye worm) hypothetical protein 0.0178 0.0227 0.0227
Brugia malayi Cathepsin L-like precursor 0.0932 0.1294 0.1294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.139 0.1943 0.5596
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Onchocerca volvulus Cathepsin L homolog 0.129 0.1801 0.3964
Giardia lamblia Transglutaminase/protease, putative 0.0035 0.0025 0.0072
Loa Loa (eye worm) prolyl oligopeptidase 0.0537 0.0735 0.0735
Loa Loa (eye worm) hypothetical protein 0.0406 0.0551 0.0551
Entamoeba histolytica grainin 2 0.0333 0.0446 0.2335
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0003 0.0003
Toxoplasma gondii calmodulin CAM2 0.0027 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0256 0.0337 0.0337
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.129 0.1801 0.1801
Plasmodium vivax calpain, putative 0.192 0.2693 1
Mycobacterium ulcerans hypothetical protein 0.0035 0.0025 0.0259
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0036 0.0103
Onchocerca volvulus 0.129 0.1801 0.3964
Schistosoma mansoni Mername-AA248 (C02 family) 0.192 0.2693 0.2693
Toxoplasma gondii ABC1 family protein 0.004 0.0032 0.0093
Schistosoma mansoni hypothetical protein 0.0306 0.0408 0.0408
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.192 0.2693 0.2693
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.0758 0.0758
Brugia malayi Eukaryotic aspartyl protease family protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.0008 0.0008
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0005 0.0013
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0025 0.0259
Trypanosoma brucei hypothetical protein 0.0553 0.0758 0.2182
Trichomonas vaginalis caltractin, putative 0.0027 0.0013 0.0039
Echinococcus multilocularis EF hand domain containing family member A2 0.031 0.0414 0.0414
Onchocerca volvulus 0.0018 0.0002 0.0003
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0067 0.0067
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0001 0.0001

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) > 10000 nM Inhibitory activity against Dipeptidyl peptidase IV ChEMBL. 16046120

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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