Detailed information for compound 348690

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 801.813 | Formula: C37H43N3O15S
  • H donors: 8 H acceptors: 12 LogP: -1.8 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 4
  • SMILES: OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NCCCN3C(=O)CC(C3=O)SC[C@@H](C(=O)O)N)[C@@H]([C@@H](O2)C)O)c2c(C1)c(O)c1c(c2O)C(=O)c2c(C1=O)cccc2OC
  • InChi: 1S/C37H43N3O15S/c1-15-30(44)19(39-7-4-8-40-24(43)10-22(35(40)49)56-14-18(38)36(50)51)9-25(54-15)55-21-12-37(52,23(42)13-41)11-17-27(21)34(48)29-28(32(17)46)31(45)16-5-3-6-20(53-2)26(16)33(29)47/h3,5-6,15,18-19,21-22,25,30,39,41,44,46,48,52H,4,7-14,38H2,1-2H3,(H,50,51)/t15-,18-,19-,21-,22?,25-,30+,37-/m0/s1
  • InChiKey: ZEJPOINQPZFTGT-SPPATNBZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Papain family cysteine protease containing protein 0.0151 0.0631 0.0631
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Leishmania major centrin, putative 0.0079 0.0239 0.0306
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0062 0.0062
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0022 0.0022
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0143 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.0151 0.0631 0.0631
Echinococcus multilocularis EF hand domain containing family member A2 0.0079 0.0239 0.0239
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0063 0.014
Echinococcus granulosus cpg binding protein 0.006 0.0134 0.0134
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0113 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0166 0.0712 0.0712
Onchocerca volvulus Cathepsin L homolog 0.0584 0.2979 0.3819
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0166 0.0712 0.191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Trypanosoma brucei Metacaspase-4 0.0143 0.0585 0.0749
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1382 0.7312 0.7312
Echinococcus multilocularis survival motor neuron protein 1 0.0479 0.2412 0.2412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0408 0.2027 0.5434
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0053 0.0097 0.0097
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0046 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0053 0.0096 0.0096
Schistosoma mansoni calmodulin related calcium binding protein 0.0079 0.0239 0.0239
Entamoeba histolytica calmodulin, putative 0.0079 0.0239 0.0735
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0156 0.0657 0.2146
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Echinococcus granulosus lamin 0.0053 0.0096 0.0096
Echinococcus multilocularis calpain 5 0.0521 0.2639 0.2639
Trypanosoma cruzi cysteine peptidase, putative 0.068 0.3501 0.3501
Trypanosoma brucei kinesin, putative 0.0364 0.1789 0.2293
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Loa Loa (eye worm) hypothetical protein 0.1877 1 1
Schistosoma mansoni calcium binding atopy-related autoantigen 0.008 0.0246 0.0246
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Loa Loa (eye worm) notch protein 0.0043 0.0042 0.0042
Schistosoma mansoni notch 0.0043 0.0042 0.0042
Brugia malayi regulator of G-protein signaling rgs-7 0.0039 0.0022 0.0022
Plasmodium vivax aspartyl proteinase, putative 0.0041 0.0031 0.0106
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0039 0.0022 0.0022
Schistosoma mansoni peroxidasin 0.0491 0.2473 0.2473
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0151 0.0631 0.2058
Brugia malayi Proteasome A-type and B-type family protein 0.0156 0.0657 0.0657
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0157 0.066 0.066
Schistosoma mansoni cathepsin C 0.0151 0.0631 0.0631
Trypanosoma cruzi cruzipain precursor, putative 0.0175 0.0761 0.0761
Echinococcus multilocularis calmodulin 0.0079 0.0239 0.0239
Trypanosoma brucei Aph-1 protein, putative 0.0094 0.0317 0.0407
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.066 0.177
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0047 0.0063 0.0063
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0486 0.0486
Echinococcus multilocularis fat cadherin tumor suppressor 0.0043 0.0042 0.0042
Trypanosoma brucei caltractin, putative 0.0079 0.0239 0.0306
Loa Loa (eye worm) hypothetical protein 0.0131 0.0518 0.0518
Trypanosoma cruzi cysteine peptidase, putative 0.0327 0.1583 0.1583
Brugia malayi Cathepsin L-like precursor 0.0584 0.2979 0.2979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Trypanosoma brucei Calpain-like protein 1.2 0.0157 0.066 0.0846
Loa Loa (eye worm) hypothetical protein 0.012 0.0463 0.0463
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Schistosoma mansoni lamin 0.0053 0.0096 0.0096
Echinococcus granulosus slit 2 protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Brugia malayi prolyl oligopeptidase family protein 0.0166 0.0712 0.0712
Brugia malayi hypothetical protein 0.0131 0.0518 0.0518
Leishmania major kinesin, putative 0.0364 0.1789 0.2293
Loa Loa (eye worm) EF hand family protein 0.0079 0.0239 0.0239
Schistosoma mansoni calmodulin 0.0079 0.0239 0.0239
Onchocerca volvulus 0.0041 0.0031 0.004
Schistosoma mansoni cathepsin s 0.0175 0.0761 0.0761
Schistosoma mansoni cpg binding protein 0.006 0.0134 0.0134
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Leishmania major cysteine peptidase A (CPA) 0.0584 0.2979 0.3819
Schistosoma mansoni centrin 0.0079 0.0239 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0166 0.0712 0.191
Schistosoma mansoni centrin-related 0.0079 0.0239 0.0239
Schistosoma mansoni caspase-3 (C14 family) 0.0216 0.0983 0.0983
Echinococcus granulosus Dipeptidyl peptidase 9 0.021 0.0948 0.0948
Echinococcus multilocularis Glycosyl transferase, family 35 0.0108 0.0397 0.0397
Trypanosoma brucei Calpain-like protein 2 0.0157 0.066 0.0846
Giardia lamblia Cathepsin L precursor 0.0151 0.0631 0.1689
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0113 0.5
Echinococcus multilocularis fibropellin Ia 0.0043 0.0042 0.0042
Echinococcus granulosus EF HAND 1 calcium binding site 0.0079 0.0239 0.0239
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0521 0.2639 0.2639
Brugia malayi Trypsin family protein 0.0131 0.0518 0.0518
Schistosoma mansoni notch 0.0043 0.0042 0.0042
Plasmodium vivax hypothetical protein, conserved 0.008 0.0246 0.0824
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0151 0.0631 0.2117
Trypanosoma cruzi cysteine peptidase, putative 0.068 0.3501 0.3501
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Onchocerca volvulus 0.0053 0.0096 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0631 0.1691
Echinococcus granulosus snurportin 1 0.0306 0.1473 0.1473
Plasmodium falciparum serine repeat antigen 2 0.0151 0.0631 0.2032
Brugia malayi Pre-SET motif family protein 0.0634 0.3255 0.3255
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0486 0.0486
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0051 0.0051
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1877 1 1
Leishmania major hypothetical protein, conserved 0.0157 0.066 0.0846
Echinococcus granulosus dnaJ subfamily B 0.0407 0.2022 0.2022
Echinococcus multilocularis neural cadherin 0.0043 0.0042 0.0042
Onchocerca volvulus Dual oxidase homolog 0.0491 0.2473 0.317
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0079 0.0239 0.0803
Brugia malayi MH2 domain containing protein 0.0117 0.0445 0.0445
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0071 0.0196 0.0251
Echinococcus granulosus peroxidasin 0.0491 0.2473 0.2473
Brugia malayi mbt repeat family protein 0.0047 0.0062 0.0062
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.2022 0.2022
Brugia malayi Cathepsin L-like precursor 0.0175 0.0761 0.0761
Loa Loa (eye worm) calpain 5 0.0364 0.1789 0.1789
Brugia malayi cathepsin L precursor 0.0151 0.0631 0.0631
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0047 0.0063 0.0209
Brugia malayi EF hand family protein 0.0079 0.0239 0.0239
Brugia malayi calpain 5 0.0364 0.1789 0.1789
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Brugia malayi EGF-like domain containing protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Echinococcus granulosus cathepsin b 0.1877 1 1
Brugia malayi hypothetical protein 0.0154 0.0647 0.0647
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Brugia malayi Animal haem peroxidase family protein 0.0491 0.2473 0.2473
Brugia malayi gamma-secretase subunit aph-1 0.024 0.1113 0.1113
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0216 0.0983 0.0983
Loa Loa (eye worm) hypothetical protein 0.0408 0.2027 0.2027
Entamoeba histolytica prolyl oligopeptidase family protein 0.0166 0.0712 0.2335
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0166 0.0712 0.2335
Echinococcus multilocularis proteasome (prosome, macropain) 0.0156 0.0657 0.0657
Entamoeba histolytica protein kinase, putative 0.0364 0.1789 0.5974
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0151 0.0631 0.0631
Leishmania major cathepsin L-like protease 0.0584 0.2979 0.3819
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0022 0.0059
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Onchocerca volvulus Peroxidase homolog 0.0491 0.2473 0.317
Onchocerca volvulus Prolyl endopeptidase homolog 0.1472 0.7801 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0151 0.0631 0.1691
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Brugia malayi hypothetical protein 0.0043 0.0045 0.0045
Trichomonas vaginalis calcium binding protein, putative 0.0079 0.0239 0.0641
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0022
Schistosoma mansoni laminin gamma-3 chain 0.0043 0.0042 0.0042
Plasmodium vivax centrin-1, putative 0.0079 0.0239 0.0803
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0151 0.0631 0.2032
Loa Loa (eye worm) hypothetical protein 0.0166 0.0712 0.0712
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0046 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0151 0.0631 0.0631
Trichomonas vaginalis calpain, putative 0.0157 0.066 0.177
Schistosoma mansoni calpain-7 (C02 family) 0.0524 0.2656 0.2656
Echinococcus granulosus protein jagged 1 0.0043 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0079 0.0239 0.0239
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0113 0.0303
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0284 0.0284
Brugia malayi Papain family cysteine protease containing protein 0.0584 0.2979 0.2979
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0157 0.066 0.0846
Trypanosoma cruzi cysteine peptidase, putative 0.068 0.3501 0.3501
Echinococcus granulosus proteasome prosome macropain 0.0156 0.0657 0.0657
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0046 0.006 0.0077
Plasmodium falciparum cysteine proteinase falcipain 3 0.0584 0.2979 1
Plasmodium vivax aspartyl proteinase, putative 0.0041 0.0031 0.0106
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0151 0.0631 0.2058
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0041 0.0031 0.0084
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0096 0.0096
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0071 0.0196 0.0588
Trypanosoma cruzi conserved protein 0.0157 0.066 0.066
Plasmodium falciparum peptidase, putative 0.0166 0.0712 0.231
Onchocerca volvulus 0.0491 0.2473 0.317
Chlamydia trachomatis glycogen phosphorylase 0.0108 0.0397 0.5
Echinococcus granulosus survival motor neuron protein 1 0.0479 0.2412 0.2412
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0113 0.0145
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.021 0.0948 0.0948
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.066 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0157 0.066 0.177
Brugia malayi cathepsin F-like cysteine proteinase 0.0175 0.0761 0.0761
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0486 0.0705
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Onchocerca volvulus Glycogen phosphorylase homolog 0.0108 0.0397 0.0509
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0062 0.0062
Toxoplasma gondii cathepsin CPL 0.0584 0.2979 0.3819
Plasmodium vivax vivapain-3 0.0327 0.1583 0.5313
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0046 0.006 0.0128
Echinococcus multilocularis cysteine protease 0.0584 0.2979 0.2979
Trichomonas vaginalis set domain proteins, putative 0.0722 0.373 1
Brugia malayi Cathepsin L-like precursor 0.0408 0.2027 0.2027
Giardia lamblia Cathepsin L precursor 0.0151 0.0631 0.1689
Toxoplasma gondii calcium-dependent protein kinase 0.008 0.0246 0.0315
Echinococcus granulosus cathepsin l1 0.0584 0.2979 0.2979
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Brugia malayi Cathepsin L-like precursor 0.0584 0.2979 0.2979
Trypanosoma cruzi Aph-1 protein, putative 0.0094 0.0317 0.0317
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Onchocerca volvulus 0.0131 0.0518 0.0664
Trypanosoma brucei mitochondrial calcium uptake 1 0.0079 0.0239 0.0306
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0143 0.0585 0.0749
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trichomonas vaginalis calcium binding proteins, putative 0.0079 0.0239 0.0641
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0151 0.0631 0.0631
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0239 0.0641
Schistosoma mansoni cathepsin F (C01 family) 0.0584 0.2979 0.2979
Leishmania major cathepsin L-like protease 0.068 0.3501 0.4488
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Schistosoma mansoni cathepsin D (A01 family) 0.0229 0.1054 0.1054
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0022 0.0022
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0521 0.2639 0.2639
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0631 0.1691
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0022 0.0022
Giardia lamblia Cathepsin B precursor 0.0151 0.0631 0.1689
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0117 0.0117
Schistosoma mansoni cpg binding protein 0.0057 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0294 0.1407 0.1407
Onchocerca volvulus 0.0491 0.2473 0.317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Schistosoma mansoni cathepsin F (C01 family) 0.0584 0.2979 0.2979
Schistosoma mansoni septate junction protein 0.0043 0.0042 0.0042
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0408 0.2027 0.5434
Onchocerca volvulus 0.0047 0.0062 0.008
Brugia malayi Kelch motif family protein 0.0047 0.0063 0.0063
Loa Loa (eye worm) calpain 0.0521 0.2639 0.2639
Loa Loa (eye worm) hypothetical protein 0.0118 0.0448 0.0448
Trypanosoma brucei calpain-like protein, putative 0.0521 0.2639 0.3383
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Echinococcus granulosus tumor protein p63 0.0675 0.3472 0.3472
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.066 0.066
Trichomonas vaginalis calpain, putative 0.0157 0.066 0.177
Entamoeba histolytica cysteine protease, putative 0.0151 0.0631 0.2058
Trypanosoma cruzi prolyl endopeptidase 0.1472 0.7801 0.7801
Echinococcus granulosus delta-like protein 1 0.0043 0.0042 0.0042
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0051 0.0051
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.066 0.066
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Echinococcus multilocularis neurocalcin 0.0079 0.0239 0.0239
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0046 0.006 0.0096
Loa Loa (eye worm) hypothetical protein 0.0131 0.0518 0.0518
Echinococcus granulosus lamin dm0 0.0053 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0131 0.0518 0.0518
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0022 0.0022
Loa Loa (eye worm) PXA domain-containing protein 0.0039 0.0022 0.0022
Brugia malayi cathepsin L-like precursor 0.0408 0.2027 0.2027
Echinococcus granulosus Glycosyl transferase family 35 0.0108 0.0397 0.0397
Echinococcus granulosus caspase 8 0.0143 0.0585 0.0585
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1461 0.7742 0.7742
Echinococcus multilocularis caspase 2 0.0309 0.1487 0.1487
Echinococcus multilocularis cysteine protease 0.0584 0.2979 0.2979
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0051 0.0051
Leishmania major proteasome beta 5 subunit, putative 0.0156 0.0657 0.0842
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0042
Brugia malayi calpain family protein 1 0.1382 0.7312 0.7312
Brugia malayi EGF-like domain containing protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0047 0.0063 0.0063
Onchocerca volvulus Huntingtin homolog 0.012 0.0463 0.0593
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Trichomonas vaginalis calcium binding protein, putative 0.0079 0.0239 0.0641
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0368 0.1807 0.1807
Leishmania major cathepsin L-like protease 0.0584 0.2979 0.3819
Trypanosoma cruzi hypothetical protein, conserved 0.0166 0.0712 0.0712
Echinococcus granulosus cysteine protease 0.0327 0.1583 0.1583
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0113 0.0113
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0322 0.1556 0.1556
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0079 0.0239 0.0239
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0593 0.3031 0.3031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0041 0.0031 0.0031
Brugia malayi Trypsin-like protease protein 5 0.0131 0.0518 0.0518
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0584 0.2979 0.2979
Brugia malayi Cathepsin L-like precursor 0.0408 0.2027 0.2027
Leishmania major centrin, putative 0.0079 0.0239 0.0306
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0022 0.0022
Trypanosoma cruzi cysteine proteinase, putative 0.0327 0.1583 0.1583
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0042
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.1028 0.149
Giardia lamblia Cysteine protease 0.0151 0.0631 0.1689
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0113 0.0113
Plasmodium falciparum plasmepsin IX 0.0202 0.0908 0.2973
Brugia malayi prolyl oligopeptidase family protein 0.021 0.0948 0.0948
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0043 0.0042 0.0042
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0041 0.0031 0.004
Toxoplasma gondii hypothetical protein 0.0157 0.066 0.0846
Echinococcus granulosus prolyl endopeptidase 0.1472 0.7801 0.7801
Onchocerca volvulus 0.008 0.0246 0.0315
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Schistosoma mansoni neuronal calcium sensor 0.0079 0.0239 0.0239
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Echinococcus multilocularis protein jagged 1 0.0043 0.0042 0.0042
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1877 1 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Echinococcus granulosus expressed protein 0.0762 0.3948 0.3948
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0156 0.0657 0.0952
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Plasmodium falciparum serine repeat antigen 5 0.0151 0.0631 0.2032
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0131 0.0518 0.0518
Entamoeba histolytica cysteine protease, putative 0.0151 0.0631 0.2058
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Onchocerca volvulus 0.0722 0.3731 0.4783
Trypanosoma brucei metacaspase MCA2 0.0143 0.0585 0.0749
Onchocerca volvulus Cathepsin L homolog 0.0151 0.0631 0.0808
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0022
Echinococcus granulosus caspase 2 0.0309 0.1487 0.1487
Plasmodium vivax proteasome subunit beta type-2, putative 0.0046 0.006 0.0201
Echinococcus multilocularis Dipeptidyl peptidase 9 0.021 0.0948 0.0948
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.066 0.177
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0157 0.066 0.066
Leishmania major cathepsin L-like protease 0.0584 0.2979 0.3819
Trypanosoma cruzi major cysteine proteinase, putative 0.0151 0.0631 0.0631
Loa Loa (eye worm) proteasome subunit beta type 1 0.0071 0.0196 0.0196
Schistosoma mansoni notch 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0092 0.0309 0.0309
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0063 0.0092
Schistosoma mansoni Mername-AA248 (C02 family) 0.0521 0.2639 0.2639
Loa Loa (eye worm) hypothetical protein 0.0157 0.066 0.066
Entamoeba histolytica hypothetical protein, conserved 0.008 0.0246 0.0756
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0097 0.0097
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0151 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0584 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0131 0.0518 0.0518
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Brugia malayi EF hand family protein 0.008 0.0246 0.0246
Echinococcus multilocularis neurogenic locus notch protein 0.0043 0.0042 0.0042
Brugia malayi prolyl oligopeptidase family protein 0.1472 0.7801 0.7801
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.012 0.0463 0.0463
Echinococcus multilocularis cathepsin L cysteine protease 0.0584 0.2979 0.2979
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0685 0.3528 0.3528
Echinococcus multilocularis hypothetical protein 0.0521 0.2639 0.2639
Loa Loa (eye worm) prolyl oligopeptidase 0.0322 0.1556 0.1556
Echinococcus granulosus fibropellin Ia 0.0043 0.0042 0.0042
Trypanosoma brucei calmodulin, putative 0.0079 0.0239 0.0306
Giardia lamblia Cathepsin B precursor 0.0151 0.0631 0.1689
Loa Loa (eye worm) RGS-3 protein 0.0039 0.0022 0.0022
Echinococcus granulosus neurogenic locus notch protein 0.0043 0.0042 0.0042
Echinococcus granulosus calbindin 32 0.008 0.0246 0.0246
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0113 0.0145
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Toxoplasma gondii EFHC1, putative 0.0079 0.0239 0.0306
Echinococcus multilocularis calcium uptake protein 1 0.008 0.0246 0.0246
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0046 0.006 0.006
Entamoeba histolytica cysteine protease, putative 0.0151 0.0631 0.2058
Onchocerca volvulus 0.0131 0.0518 0.0664
Onchocerca volvulus 0.0166 0.0712 0.0913
Brugia malayi hypothetical protein 0.0166 0.0712 0.0712
Giardia lamblia Glycogen phosphorylase 0.0108 0.0397 0.1019
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0157 0.066 0.0846
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0143 0.0585 0.0585
Plasmodium falciparum serine repeat antigen 9 0.0151 0.0631 0.2032
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0022 0.0022
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0079 0.0239 0.0735
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0022
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0113 0.0308
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Trypanosoma cruzi cruzipain precursor, putative 0.068 0.3501 0.3501
Onchocerca volvulus Peroxidasin homolog 0.0491 0.2473 0.317
Toxoplasma gondii centrin, putative 0.0079 0.0239 0.0306
Onchocerca volvulus Peroxidase homolog 0.0491 0.2473 0.317
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0156 0.0657 0.0657
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0042
Trichomonas vaginalis calmodulin-2, putative 0.0079 0.0239 0.0641
Trichomonas vaginalis centrin, putative 0.0079 0.0239 0.0641
Echinococcus granulosus acylamino acid releasing enzyme 0.0166 0.0712 0.0712
Echinococcus multilocularis geminin 0.0165 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0143 0.0585 0.0749
Plasmodium vivax vivapain-2 0.0584 0.2979 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.2639
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0397 0.1268
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0039 0.0022 0.0022
Trypanosoma brucei centrin-3 0.0079 0.0239 0.0306
Entamoeba histolytica cysteine proteinase, putative 0.0584 0.2979 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.0309 0.0309
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0445 0.0445
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Loa Loa (eye worm) hypothetical protein 0.0154 0.0647 0.0647
Leishmania major proteasome beta 2 subunit, putative 0.0046 0.006 0.0077
Loa Loa (eye worm) animal heme peroxidase 0.0491 0.2473 0.2473
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0022 0.0022
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Brugia malayi EGF-like domain containing protein 0.0043 0.0042 0.0042
Trypanosoma cruzi I/6 autoantigen, putative 0.0079 0.0239 0.0239
Leishmania major hypothetical protein, conserved 0.008 0.0246 0.0315
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0322 0.1556 0.1994
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0151 0.0631 0.1691
Brugia malayi cathepsin Z-like cysteine proteinase 0.0151 0.0631 0.0631
Trypanosoma cruzi metacaspase, putative 0.0143 0.0585 0.0585
Echinococcus multilocularis integrin alpha ps 0.0067 0.0174 0.0174
Trypanosoma brucei protein I/6 0.0079 0.0239 0.0306
Brugia malayi prolyl oligopeptidase family protein 0.0322 0.1556 0.1556
Leishmania major programmed cell death 6 protein-like protein 0.0079 0.0239 0.0306
Entamoeba histolytica cysteine protease, putative 0.0584 0.2979 1
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.021 0.0948 0.1215
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Loa Loa (eye worm) hypothetical protein 0.0151 0.0631 0.0631
Giardia lamblia Hypothetical protein 0.0151 0.0631 0.1689
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0031
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0151 0.0631 0.2117
Echinococcus multilocularis neurogenic locus protein delta 0.0043 0.0042 0.0042
Brugia malayi Peroxidasin 0.0491 0.2473 0.2473
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0151 0.0631 0.1689
Giardia lamblia Cathepsin L-like protease 0.0151 0.0631 0.1689
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.3383
Loa Loa (eye worm) hypothetical protein 0.0408 0.2027 0.2027
Trypanosoma cruzi oligopeptidase b 0.0593 0.3031 0.3031
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0022 0.0022
Brugia malayi Trypsin family protein 0.0131 0.0518 0.0518
Trypanosoma cruzi metacaspase 5, putative 0.0143 0.0585 0.0585
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0397 0.0397
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0151 0.0631 0.0631
Onchocerca volvulus Slit protein homolog 0.0043 0.0042 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0309 0.0309
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.048 0.048
Onchocerca volvulus Putative cubilin 0.0043 0.0042 0.0053
Plasmodium vivax aspartyl protease, putative 0.0202 0.0908 0.3047
Brugia malayi Cathepsin L-like cysteine proteinase 0.0408 0.2027 0.2027
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0143 0.0585 0.0749
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0151 0.0631 0.0631
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Trypanosoma cruzi 20S proteasome subunit 0.0046 0.006 0.006
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0046 0.006 0.006
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Entamoeba histolytica calcium-binding protein, putative 0.0079 0.0239 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0685 0.3528 0.9459
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0327 0.1583 0.1583
Brugia malayi Calmodulin-like protein 0.0079 0.0239 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0585 0.1567
Plasmodium vivax vivapain-1 0.0327 0.1583 0.5313
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0327 0.1583 0.2029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.066 0.066
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Giardia lamblia Cysteine protease 0.0151 0.0631 0.1689
Loa Loa (eye worm) programmed cell death protein 6 0.008 0.0246 0.0246
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.024 0.1113 0.1113
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0239 0.0641
Entamoeba histolytica hypothetical protein 0.0151 0.0631 0.2058
Trypanosoma brucei centrin, putative 0.0079 0.0239 0.0306
Brugia malayi EGF-like domain containing protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) calpain family protein 1 0.1017 0.5333 0.5333
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0368 0.1807 0.1807
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0151 0.0631 0.0631
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0151 0.0631 0.2117
Schistosoma mansoni reticulocalbin 0.0079 0.0239 0.0239
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0113 0.0113
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1461 0.7742 0.7742
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0585 0.1567
Trypanosoma cruzi kinesin, putative 0.0364 0.1789 0.1789
Loa Loa (eye worm) animal heme peroxidase 0.0491 0.2473 0.2473
Trypanosoma cruzi centrin-3 0.0079 0.0239 0.0239
Onchocerca volvulus 0.0099 0.0345 0.0443
Echinococcus granulosus calmodulin 0.0079 0.0239 0.0239
Echinococcus multilocularis neuronal calcium sensor 0.0079 0.0239 0.0239
Schistosoma mansoni gamma-secretase subunit aph-1 0.024 0.1113 0.1113
Echinococcus multilocularis calpain A 0.1462 0.7748 0.7748
Onchocerca volvulus 0.086 0.4482 0.5745
Toxoplasma gondii aspartyl protease 0.0041 0.0031 0.004
Brugia malayi proteasome subunit beta type 2 0.0046 0.006 0.006
Onchocerca volvulus 0.0151 0.0631 0.0808
Giardia lamblia Cathepsin B precursor 0.0151 0.0631 0.1689
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.2639
Schistosoma mansoni calmodulin 0.0079 0.0239 0.0239
Brugia malayi Calcium binding EGF domain containing protein 0.0043 0.0042 0.0042
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Plasmodium vivax hypothetical protein, conserved 0.0143 0.0585 0.1962
Trypanosoma brucei prolyl oligopeptidase, putative 0.0593 0.3031 0.3886
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0022 0.0022
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0584 0.2979 0.2979
Schistosoma mansoni hypothetical protein 0.0157 0.066 0.066
Onchocerca volvulus Peroxidasin homolog 0.0491 0.2473 0.317
Loa Loa (eye worm) hypothetical protein 0.0309 0.1487 0.1487
Onchocerca volvulus Chorion peroxidase homolog 0.0491 0.2473 0.317
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Echinococcus multilocularis notch 0.0043 0.0042 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.0327 0.1583 0.5278
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0051 0.0051
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0151 0.0631 0.1689
Toxoplasma gondii calmodulin CAM1 0.008 0.0246 0.0315
Echinococcus granulosus EF hand domain containing family member A2 0.008 0.0246 0.0246
Schistosoma mansoni survival motor neuron protein 0.0098 0.034 0.034
Brugia malayi mbt repeat family protein 0.0047 0.0062 0.0062
Loa Loa (eye worm) cysteine protease 0.0584 0.2979 0.2979
Brugia malayi A-kinase anchor protein 10, precursor 0.0039 0.0022 0.0022
Schistosoma mansoni mitochondrial solute carrier 0.0079 0.0239 0.0239
Schistosoma mansoni ap endonuclease 0.0056 0.0113 0.0113
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Onchocerca volvulus Cathepsin F homolog 0.0584 0.2979 0.3819
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0051 0.0051
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0063 0.014
Loa Loa (eye worm) MBCTL1 0.0053 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.066 0.177
Echinococcus granulosus neurogenic locus notch protein 0.0043 0.0042 0.0042
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0486 0.0486
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.1472 0.7801 0.7801
Plasmodium vivax SET domain protein, putative 0.0092 0.0309 0.1038
Leishmania major calmodulin-like protein 0.0079 0.0239 0.0306
Giardia lamblia Proteasome subunit beta type 2 0.0046 0.006 0.0052
Plasmodium vivax proteasome subunit beta type-1, putative 0.0071 0.0196 0.0657
Echinococcus multilocularis neurogenic locus notch protein 4 0.0043 0.0042 0.0042
Brugia malayi cathepsin F-like cysteine proteinase 0.0151 0.0631 0.0631
Brugia malayi hypothetical protein 0.0039 0.0022 0.0022
Brugia malayi Integrin alpha pat-2 precursor 0.015 0.0623 0.0623
Trypanosoma cruzi calmodulin, putative 0.0079 0.0239 0.0239
Toxoplasma gondii troponin c, isotype gamma, putative 0.0079 0.0239 0.0306
Giardia lamblia Cysteine protease 0.0151 0.0631 0.1689
Echinococcus multilocularis calmodulin 0.0079 0.0239 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0022 0.0059
Echinococcus multilocularis musashi 0.0053 0.0096 0.0096
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.0309 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0585 0.1567
Plasmodium falciparum metacaspase 1 0.0143 0.0585 0.1877
Schistosoma mansoni rab 0.0079 0.0239 0.0239
Schistosoma mansoni neuronal calcium sensor 0.0079 0.0239 0.0239
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1472 0.7801 0.7801
Brugia malayi Animal haem peroxidase family protein 0.0491 0.2473 0.2473
Schistosoma mansoni calpain (C02 family) 0.0521 0.2639 0.2639
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1461 0.7742 0.7742
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0504 0.2549 0.2549
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0043 0.0042 0.0053
Plasmodium falciparum proteasome subunit beta type-5 0.0156 0.0657 0.2121
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0051 0.0051
Echinococcus granulosus gamma secretase subunit aph 1 0.024 0.1113 0.1113
Onchocerca volvulus 0.0584 0.2979 0.3819
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0022
Brugia malayi Delta serrate ligand family protein 0.0043 0.0042 0.0042
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0022 0.0022
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.021 0.0948 0.1215
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0151 0.0631 0.2117
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0113 0.0303
Giardia lamblia Proteasome subunit beta type 1 0.0071 0.0196 0.0442
Echinococcus granulosus cathepsin l cysteine peptidase 0.0584 0.2979 0.2979
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0157 0.066 0.0846
Loa Loa (eye worm) hypothetical protein 0.1225 0.6461 0.6461
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0593 0.3031 1
Entamoeba histolytica hypothetical protein, conserved 0.0166 0.0712 0.2335
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 0.1473 0.1473
Loa Loa (eye worm) prolyl oligopeptidase 0.0166 0.0712 0.0712
Trypanosoma cruzi metacaspase 5, putative 0.0143 0.0585 0.0585
Mycobacterium ulcerans hypothetical protein 0.0131 0.0518 0.171
Brugia malayi Integrin beta pat-3 precursor 0.0307 0.1476 0.1476
Leishmania major hypothetical protein, unknown function 0.0157 0.066 0.0846
Trichomonas vaginalis hypothetical protein 0.0157 0.066 0.177
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0039 0.0022 0.0059
Plasmodium vivax serine-repeat antigen (SERA) 0.0151 0.0631 0.2117
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0099 0.0099
Brugia malayi Papain family cysteine protease containing protein 0.0327 0.1583 0.1583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0157 0.066 0.066
Echinococcus multilocularis protein jagged 2 0.0043 0.0042 0.0042
Giardia lamblia Alanyl dipeptidyl peptidase 0.0166 0.0712 0.1924
Schistosoma mansoni hypothetical protein 0.0165 0.0707 0.0707
Schistosoma mansoni hypothetical protein 0.0306 0.1473 0.1473
Schistosoma mansoni glycogen phosphorylase 0.0108 0.0397 0.0397
Trypanosoma brucei calpain-like protein, putative 0.0521 0.2639 0.3383
Echinococcus granulosus protein jagged 2 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0151 0.0631 0.0631
Echinococcus granulosus neurocalcin 0.0079 0.0239 0.0239
Brugia malayi Blistered cuticle protein 3 0.0491 0.2473 0.2473
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Trichomonas vaginalis calcineurin B subunit, putative 0.0079 0.0239 0.0641
Schistosoma mansoni neuronal calcium sensor 0.0079 0.0239 0.0239
Echinococcus multilocularis EF hand domain containing family member A2 0.008 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.086 0.4482 0.4482
Loa Loa (eye worm) proteasome subunit beta type 2 0.0046 0.006 0.006
Echinococcus multilocularis calpain family protein 1, d 0.1017 0.5333 0.5333
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0113 0.0113
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0131 0.0518 0.0518
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0166 0.0712 0.0913
Toxoplasma gondii cathepsin CPC1 0.0151 0.0631 0.0808
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0079 0.0239 0.0239
Plasmodium vivax hypothetical protein, conserved 0.0166 0.0712 0.2392
Entamoeba histolytica cysteine proteinase 2 0.0327 0.1583 0.5278
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0079 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.2639
Loa Loa (eye worm) hypothetical protein 0.0079 0.0239 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0585 0.1567
Schistosoma mansoni cpg binding protein 0.006 0.0134 0.0134
Trypanosoma brucei cysteine peptidase, putative 0.0157 0.066 0.0846
Echinococcus multilocularis Mastin 0.0131 0.0518 0.0518
Trypanosoma cruzi metacaspase, putative 0.0143 0.0585 0.0585
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1472 0.7801 1
Toxoplasma gondii EF hand domain-containing protein 0.0079 0.0239 0.0306
Schistosoma mansoni peroxidasin 0.0491 0.2473 0.2473
Brugia malayi Cathepsin L-like precursor 0.0584 0.2979 0.2979
Trichomonas vaginalis calpain, putative 0.0157 0.066 0.177
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0113 0.0205
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0071 0.0196 0.0251
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Giardia lamblia Cathepsin B precursor 0.0151 0.0631 0.1689
Loa Loa (eye worm) calpain family protein 1 0.1382 0.7312 0.7312
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0071 0.0196 0.0525
Loa Loa (eye worm) cathepsin B 0.0685 0.3528 0.3528
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0151 0.0631 0.1691
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0151 0.0631 0.1691
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0022 0.0022
Brugia malayi EGF-like domain containing protein 0.0043 0.0042 0.0042
Schistosoma mansoni calpain-7 (C02 family) 0.0524 0.2656 0.2656
Entamoeba histolytica cysteine protease, putative 0.0151 0.0631 0.2058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0486 0.0623
Plasmodium falciparum calpain 0.0157 0.066 0.2133
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.0631 0.1691
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0151 0.0631 0.1691
Schistosoma mansoni slit 0.0043 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Trypanosoma cruzi calmodulin, putative 0.0079 0.0239 0.0239
Schistosoma mansoni microtubule-associated protein tau 0.1409 0.7461 0.7461
Giardia lamblia Cathepsin B precursor 0.0685 0.3528 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0156 0.0657 0.0657
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0041 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Echinococcus multilocularis cathepsin L cysteine protease 0.0584 0.2979 0.2979
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Brugia malayi Animal haem peroxidase family protein 0.0491 0.2473 0.2473
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.066 0.177
Brugia malayi PXA domain containing protein 0.0039 0.0022 0.0022
Echinococcus multilocularis cathepsin b 0.1877 1 1
Trypanosoma brucei centrin, putative 0.0079 0.0239 0.0306
Echinococcus granulosus integrin beta 2 0.0227 0.1044 0.1044
Loa Loa (eye worm) hypothetical protein 0.1382 0.7312 0.7312
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0079 0.0239 0.0641
Echinococcus granulosus integrin alpha ps 0.0067 0.0174 0.0174
Schistosoma mansoni notch 0.0043 0.0043 0.0043
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0079 0.0239 0.0239
Leishmania major oligopeptidase b 0.0593 0.3031 0.3886
Echinococcus granulosus notch 0.0043 0.0042 0.0042
Leishmania major i/6 autoantigen-like protein 0.0079 0.0239 0.0306
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0051 0.0051
Echinococcus multilocularis acylamino acid releasing enzyme 0.0166 0.0712 0.0712
Schistosoma mansoni cathepsin B (C01 family) 0.0151 0.0631 0.0631
Trichomonas vaginalis calmodulin, putative 0.008 0.0246 0.0658
Toxoplasma gondii cathepsin CPC2 0.0151 0.0631 0.0808
Entamoeba histolytica cysteine proteinase, putative 0.0327 0.1583 0.5278
Brugia malayi Trypsin family protein 0.0131 0.0518 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.0631 0.1691
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0022 0.0022
Onchocerca volvulus 0.0131 0.0518 0.0664
Schistosoma mansoni calpain-2 (C02 family) 0.0157 0.066 0.066
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0593 0.3031 0.4394
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0521 0.2639 0.2639
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Leishmania major hypothetical protein, conserved 0.0079 0.0239 0.0306
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Trypanosoma cruzi Aph-1 protein, putative 0.0094 0.0317 0.0317
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0113 0.0276
Trichomonas vaginalis myosin light chain 1, putative 0.0079 0.0239 0.0641
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0079 0.0239 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0151 0.0631 0.1691
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0079 0.0239 0.0306
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0195 0.0867 0.0867
Entamoeba histolytica cysteine protease, putative 0.0151 0.0631 0.2058
Brugia malayi hypothetical protein 0.0491 0.2473 0.2473
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0397 0.0397
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0486 0.0623
Loa Loa (eye worm) hypothetical protein 0.0049 0.0073 0.0073
Brugia malayi hypothetical protein 0.0479 0.2412 0.2412
Brugia malayi Papain family cysteine protease containing protein 0.0327 0.1583 0.1583
Trypanosoma brucei I/6 autoantigen 0.0079 0.0239 0.0306
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0113 0.0379
Schistosoma mansoni hypothetical protein 0.0407 0.2022 0.2022
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0521 0.2639 0.2639
Brugia malayi Animal haem peroxidase family protein 0.0491 0.2473 0.2473
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0022 0.0022
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0151 0.0631 0.0631
Schistosoma mansoni calpain C (C02 family) 0.0521 0.2639 0.2639
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Trypanosoma cruzi metacaspase, putative 0.0143 0.0585 0.0585
Schistosoma mansoni intermediate filament proteins 0.0053 0.0096 0.0096
Brugia malayi Papain family cysteine protease containing protein 0.0151 0.0631 0.0631
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0151 0.0631 0.0631
Entamoeba histolytica prolyl oligopeptidase family protein 0.0166 0.0712 0.2335
Brugia malayi Trypsin family protein 0.0131 0.0518 0.0518
Entamoeba histolytica cysteine proteinase 1, putative 0.0327 0.1583 0.5278
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Toxoplasma gondii aspartyl protease ASP1 0.0041 0.0031 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.0631 0.1691
Schistosoma mansoni hypothetical protein 0.0079 0.0239 0.0239
Brugia malayi hypothetical protein 0.0041 0.0031 0.0031
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0022 0.0022
Trypanosoma brucei proteasome beta 6 subunit 0.0071 0.0196 0.0251
Schistosoma mansoni ef hand domain family member A2 0.0079 0.0239 0.0239
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Loa Loa (eye worm) blistered cuticle protein 3 0.0491 0.2473 0.2473
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.3383
Onchocerca volvulus 0.0079 0.0239 0.0306
Brugia malayi Papain family cysteine protease containing protein 0.0151 0.0631 0.0631
Loa Loa (eye worm) calpain D 0.0157 0.066 0.066
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0063 0.014
Echinococcus multilocularis lamin dm0 0.0053 0.0096 0.0096
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0031
Trypanosoma brucei antigen, putative 0.0521 0.2639 0.3383
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0216 0.0983 0.0983
Echinococcus multilocularis cathepsin b 0.1877 1 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0166 0.0712 0.2335
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0062 0.008
Leishmania major calmodulin-like protein 0.0079 0.0239 0.0306
Echinococcus multilocularis microtubule associated protein 2 0.1409 0.7461 0.7461
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0022 0.0022
Onchocerca volvulus 0.0584 0.2979 0.3819
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0022 0.0059
Schistosoma mansoni lamin 0.0053 0.0096 0.0096
Brugia malayi aspartic protease BmAsp-1, identical 0.0041 0.0031 0.0031
Trypanosoma brucei prolyl endopeptidase 0.1472 0.7801 1
Schistosoma mansoni caspase-7 (C14 family) 0.0216 0.0983 0.0983
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0156 0.0657 0.0657
Trichomonas vaginalis calcium binding protein, putative 0.0079 0.0239 0.0641
Echinococcus multilocularis gamma secretase subunit aph 1 0.024 0.1113 0.1113
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1305 0.6898 1
Giardia lamblia Cathepsin B precursor 0.0685 0.3528 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0022 0.0059
Onchocerca volvulus 0.0043 0.0042 0.0053
Giardia lamblia Cathepsin L precursor 0.0151 0.0631 0.1689
Echinococcus granulosus intermediate filament protein 0.0053 0.0096 0.0096
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.066 0.177
Schistosoma mansoni integrin beta subunit 0.0181 0.0791 0.0791
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.0309 0.0396
Trichomonas vaginalis calcineurin B subunit, putative 0.008 0.0246 0.0658
Loa Loa (eye worm) aspartyl protease 6 0.0041 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0022 0.0022
Echinococcus multilocularis glycogen phosphorylase 0.0108 0.0397 0.0397
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0079 0.0239 0.0641
Brugia malayi Calcium binding EGF domain containing protein 0.0043 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0098 0.034 0.034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0521 0.2639 0.2639
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Leishmania major metacaspase, putative 0.0143 0.0585 0.0749
Schistosoma mansoni reticulocalbin 0.008 0.0246 0.0246
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0131 0.0518 0.0518
Trypanosoma cruzi metacaspase, putative 0.0143 0.0585 0.0585
Echinococcus granulosus calpain A 0.0521 0.2639 0.2639
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0113 0.0164
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Echinococcus granulosus apoptotic protease activating factor 1 0.0166 0.0712 0.0712
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0151 0.0631 0.0631
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0041 0.0031 0.0031
Schistosoma mansoni memapsin-2 (A01 family) 0.0472 0.2375 0.2375
Echinococcus granulosus calcium uptake protein 1 0.008 0.0246 0.0246
Toxoplasma gondii exonuclease III APE 0.0056 0.0113 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Echinococcus multilocularis cathepsin L 0.0151 0.0631 0.0631
Trypanosoma brucei calpain, putative 0.0157 0.066 0.0846
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.066
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1877 1 1
Trypanosoma brucei calpain-like protein, putative 0.0521 0.2639 0.3383
Plasmodium vivax plasmepsin V, putative 0.0041 0.0031 0.0106
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0585 0.1567
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Trichomonas vaginalis calcium binding protein, putative 0.0079 0.0239 0.0641
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trypanosoma cruzi centrin, putative 0.0079 0.0239 0.0239
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0151 0.0631 0.2117
Echinococcus granulosus programmed cell death protein 0.0079 0.0239 0.0239
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.021 0.0948 0.0948
Loa Loa (eye worm) integrin alpha pat-2 0.0231 0.1064 0.1064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Onchocerca volvulus 0.0043 0.0042 0.0053
Onchocerca volvulus Huntingtin homolog 0.012 0.0463 0.0593
Onchocerca volvulus 0.0079 0.0239 0.0306
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0041 0.0031 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0151 0.0631 0.1691
Onchocerca volvulus 0.0053 0.0096 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Brugia malayi GCC2 and GCC3 family protein 0.0043 0.0042 0.0042
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0584 0.2979 1
Echinococcus granulosus microtubule associated protein 2 0.1409 0.7461 0.7461
Brugia malayi prolyl oligopeptidase family protein 0.0166 0.0712 0.0712
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0156 0.0657 0.0842
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0309 0.0309
Brugia malayi intermediate filament protein 0.0053 0.0096 0.0096
Trypanosoma brucei metacaspase MCA3 0.0143 0.0585 0.0749
Trypanosoma brucei oligopeptidase b 0.0593 0.3031 0.3886
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.021 0.0948 0.1215
Giardia lamblia Encystation-specific protease 0.0151 0.0631 0.1689
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0062 0.0062
Onchocerca volvulus 0.0154 0.0647 0.0829
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0157 0.066 0.0846
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0322 0.1556 0.1556
Loa Loa (eye worm) hypothetical protein 0.0131 0.0518 0.0518
Schistosoma mansoni ap endonuclease 0.0056 0.0113 0.0113
Leishmania major cathepsin L-like protease 0.068 0.3501 0.4488
Plasmodium falciparum serine repeat antigen 4 0.0151 0.0631 0.2032
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0151 0.0631 0.2117
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0079 0.0239 0.0239
Trypanosoma brucei calpain-like protein, putative 0.0521 0.2639 0.3383
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0151 0.0631 0.1689
Toxoplasma gondii EGF family domain-containing protein 0.0043 0.0042 0.0053
Plasmodium vivax unspecified product 0.0175 0.0761 0.2556
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Echinococcus multilocularis programmed cell death protein 0.0079 0.0239 0.0239
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0113 0.0372
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0593 0.3031 1
Giardia lamblia Cathepsin L precursor 0.0151 0.0631 0.1689
Brugia malayi EGF-like domain containing protein 0.0043 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.3383
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0031
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0397 0.1064
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0166 0.0712 0.0913
Brugia malayi cathepsin Z-like cysteine proteinase 0.0151 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0046 0.006 0.016
Schistosoma mansoni cell polarity protein 0.0043 0.0042 0.0042
Brugia malayi CXXC zinc finger family protein 0.0057 0.0117 0.0117
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0175 0.0761 0.0761
Onchocerca volvulus 0.0584 0.2979 0.3819
Onchocerca volvulus 0.0098 0.034 0.0436
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Loa Loa (eye worm) hypothetical protein 0.1017 0.5333 0.5333
Schistosoma mansoni hypothetical protein 0.0166 0.0712 0.0712
Echinococcus multilocularis enteropeptidase 0.0131 0.0518 0.0518
Onchocerca volvulus Neurogenic locus notch homolog 0.0043 0.0043 0.0055
Plasmodium falciparum metacaspase-like protein 0.0143 0.0585 0.1877
Echinococcus granulosus neural cadherin 0.0043 0.0042 0.0042
Trichomonas vaginalis centrin, putative 0.0079 0.0239 0.0641
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0593 0.3031 0.3031
Brugia malayi Muscle positioning protein 4 0.0043 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0157 0.066 0.177
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0051 0.0051
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0071 0.0196 0.0557
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Brugia malayi hypothetical protein 0.0047 0.0063 0.0063
Echinococcus granulosus Regulator of G protein signaling 20 0.0039 0.0022 0.0022
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0157 0.066 0.066
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0397 0.0397
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0113 0.0113
Schistosoma mansoni cathepsin S (C01 family) 0.0151 0.0631 0.0631
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0097 0.0097
Trichomonas vaginalis glycogen phosphorylase, putative 0.0108 0.0397 0.1064
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0131 0.0518 0.0518
Plasmodium falciparum serine repeat antigen 3 0.0151 0.0631 0.2032
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0097 0.0097
Plasmodium vivax unspecified product 0.0327 0.1583 0.5313
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0071 0.0196 0.0196
Toxoplasma gondii hypothetical protein 0.0166 0.0712 0.0913
Echinococcus granulosus calumenin 0.008 0.0246 0.0246
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0022 0.0022
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0685 0.3528 0.4523
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0022 0.0022
Toxoplasma gondii cathepsin B 0.0685 0.3528 0.4523
Onchocerca volvulus Cell death protein 3 homolog 0.0309 0.1487 0.1907
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Echinococcus granulosus neurogenic locus notch protein 4 0.0043 0.0042 0.0042
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0327 0.1583 0.1583
Onchocerca volvulus 0.0041 0.0031 0.004
Brugia malayi cathepsin L-like cysteine proteinase 0.0151 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0096 0.0096
Plasmodium vivax calpain, putative 0.0521 0.2639 0.886
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0151 0.0631 0.1689
Brugia malayi notch-like transmembrane receptor 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.021 0.0948 0.1215
Brugia malayi calpain D 0.0157 0.066 0.066
Brugia malayi calpain 7 0.0521 0.2639 0.2639
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0585 0.1567
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0521 0.2639 0.3383
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0156 0.0657 0.176
Brugia malayi Pepsin A precursor 0.0041 0.0031 0.0031
Echinococcus multilocularis caspase 8 0.0143 0.0585 0.0585
Onchocerca volvulus 0.0043 0.0042 0.0053
Loa Loa (eye worm) hypothetical protein 0.0047 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0131 0.0518 0.0518
Echinococcus multilocularis centrin 2 0.0079 0.0239 0.0239
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0131 0.0518 0.0518
Echinococcus granulosus calpain 5 0.0521 0.2639 0.2639
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0584 0.2979 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0584 0.2979 0.7987
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1472 0.7801 0.7801
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0022 0.0022
Plasmodium vivax plasmepsin IV, putative 0.0041 0.0031 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.0631 0.1691
Loa Loa (eye worm) hypothetical protein 0.0083 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0045
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0131 0.0518 0.0518
Trypanosoma cruzi oligopeptidase b 0.0593 0.3031 0.3031
Trypanosoma brucei Calpain-like protein CALP1.3 0.0157 0.066 0.0846
Brugia malayi carbohydrate phosphorylase 0.0108 0.0397 0.0397
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0368 0.1807 0.1807
Trypanosoma cruzi centrin, putative 0.0079 0.0239 0.0239
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.0345 0.0345
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Entamoeba histolytica calpain large subunit domain III containing protein 0.0364 0.1789 0.5974
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0151 0.0631 0.0631
Schistosoma mansoni cercarial elastase (S01 family) 0.0131 0.0518 0.0518
Brugia malayi Eukaryotic aspartyl protease family protein 0.0041 0.0031 0.0031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Echinococcus multilocularis Regulator of G protein signaling 20 0.0039 0.0022 0.0022
Trypanosoma cruzi cysteine protease, putative 0.0327 0.1583 0.1583
Plasmodium vivax aspartyl protease, putative 0.0041 0.0031 0.0106
Echinococcus multilocularis apoptotic protease activating factor 1 0.0166 0.0712 0.0712
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0022 0.0022
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0079 0.0239 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Onchocerca volvulus 0.0131 0.0518 0.0664
Brugia malayi Cathepsin L-like precursor 0.0584 0.2979 0.2979
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0156 0.0657 0.0657
Plasmodium vivax serine-repeat antigen (SERA) 0.0151 0.0631 0.2117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.0631 0.1691
Plasmodium falciparum plasmepsin X 0.0202 0.0908 0.2973
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.041 0.0526
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0042
Echinococcus granulosus glycoprotein Antigen 5 0.0131 0.0518 0.0518
Echinococcus granulosus cathepsin L 0.0151 0.0631 0.0631
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0593 0.3031 0.3886
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Echinococcus multilocularis prolyl endopeptidase 0.1472 0.7801 0.7801
Echinococcus multilocularis integrin alpha 3 0.0115 0.0433 0.0433
Onchocerca volvulus 0.0584 0.2979 0.3819
Brugia malayi Cathepsin L-like precursor 0.0584 0.2979 0.2979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Loa Loa (eye worm) ctsf protein 0.0584 0.2979 0.2979
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0073 0.0073
Plasmodium vivax metacaspase 1, putative 0.0143 0.0585 0.1962
Loa Loa (eye worm) hypothetical protein 0.0079 0.0239 0.0239
Brugia malayi Animal haem peroxidase family protein 0.0491 0.2473 0.2473
Trypanosoma brucei metacaspase 5, putative 0.0143 0.0585 0.0749
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0113 0.0113
Echinococcus granulosus neuronal calcium sensor 0.0079 0.0239 0.0239
Echinococcus granulosus enteropeptidase 0.0131 0.0518 0.0518
Echinococcus granulosus cathepsin l1 0.0408 0.2027 0.2027
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0071 0.0196 0.0196
Echinococcus multilocularis slit 2 protein 0.0043 0.0042 0.0042
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.021 0.0948 0.0948
Echinococcus multilocularis snurportin 1 0.0306 0.1473 0.1473
Echinococcus granulosus EF hand domain containing family member A2 0.0079 0.0239 0.0239
Echinococcus granulosus caspase 0.0216 0.0983 0.0983
Trypanosoma cruzi cysteine peptidase, putative 0.0175 0.0761 0.0761
Plasmodium falciparum cysteine proteinase falcipain 1 0.0327 0.1583 0.5263
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0166 0.0712 0.0712
Echinococcus multilocularis neurogenic locus protein delta 0.0043 0.0042 0.0042
Loa Loa (eye worm) fibroinase 0.0584 0.2979 0.2979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1583 0.4243
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0521 0.2639 0.2639
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0166 0.0712 0.0712
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0479 0.2412 0.2412
Schistosoma mansoni notch 0.0043 0.0042 0.0042
Trypanosoma cruzi I/6 autoantigen, putative 0.0079 0.0239 0.0239
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.066 0.066
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0022 0.0022
Entamoeba histolytica cysteine proteinase, putative 0.0408 0.2027 0.678
Plasmodium falciparum serine repeat antigen 7 0.0151 0.0631 0.2032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Giardia lamblia Cysteine protease 0.0151 0.0631 0.1689
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0309 0.0309
Onchocerca volvulus 0.0584 0.2979 0.3819
Echinococcus multilocularis cathepsin L 0.0327 0.1583 0.1583
Brugia malayi Cytochrome P450 family protein 0.0053 0.0099 0.0099
Plasmodium falciparum serine repeat antigen 1 0.0151 0.0631 0.2032
Brugia malayi calpain 5 0.0157 0.066 0.066
Entamoeba histolytica cysteine protease, putative 0.0151 0.0631 0.2058
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0166 0.0712 0.0712
Entamoeba histolytica grainin, putative 0.008 0.0246 0.0756
Echinococcus granulosus cathepsin L cysteine proteinase 0.0584 0.2979 0.2979
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Echinococcus granulosus glycogen phosphorylase 0.0108 0.0397 0.0397
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0022 0.0022
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0151 0.0631 0.2032
Echinococcus multilocularis caspase 3 0.0073 0.0207 0.0207
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0046 0.006 0.0077
Echinococcus granulosus cathepsin L cysteine protease 0.0327 0.1583 0.1583
Loa Loa (eye worm) hypothetical protein 0.0175 0.0761 0.0761
Echinococcus multilocularis regulator of G protein signaling 0.0039 0.0022 0.0022
Giardia lamblia Cathepsin L precursor 0.0151 0.0631 0.1689
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0486 0.0486
Brugia malayi proteasome subunit beta type 1 0.0071 0.0196 0.0196
Toxoplasma gondii preprocathepsin c precursor, putative 0.0151 0.0631 0.0808
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0073 0.0073
Echinococcus granulosus transmembrane protease serine 3 0.0131 0.0518 0.0518
Loa Loa (eye worm) animal heme peroxidase 0.0491 0.2473 0.2473
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0079 0.0239 0.0306
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0097 0.0097
Brugia malayi calpain family protein 1 0.1382 0.7312 0.7312
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0073 0.0073
Trypanosoma brucei Calpain-like protein 1.1 0.0157 0.066 0.0846
Toxoplasma gondii prolyl endopeptidase 0.1472 0.7801 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0151 0.0631 0.0631
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0046 0.006 0.006
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0584 0.2979 0.2979
Brugia malayi fibroinase precursor 0.0151 0.0631 0.0631
Mycobacterium tuberculosis Probable peptidase 0.0593 0.3031 0.4394
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0079 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0143 0.0585 0.0585
Schistosoma mansoni caspase-7 (C14 family) 0.0309 0.1487 0.1487
Schistosoma mansoni integrin alpha-ps 0.0067 0.0174 0.0174
Echinococcus multilocularis integrin beta 2 0.0227 0.1044 0.1044
Echinococcus granulosus integrin alpha 3 0.0115 0.0433 0.0433
Trypanosoma brucei hypothetical protein 0.0157 0.066 0.0846
Plasmodium falciparum serine repeat antigen 6 0.0151 0.0631 0.2032
Echinococcus multilocularis programmed cell death protein 0.0079 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0131 0.0518 0.0518
Entamoeba histolytica glycogen phosphorylase, putative 0.0108 0.0397 0.1268
Entamoeba histolytica cysteine proteinase, putative 0.0584 0.2979 1
Onchocerca volvulus 0.0043 0.0042 0.0053
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0062 0.0062
Echinococcus multilocularis cpg binding protein 0.006 0.0134 0.0134
Onchocerca volvulus 0.0408 0.2027 0.2598
Leishmania major calpain protease-like protein 0.0157 0.066 0.0846
Giardia lamblia Alanyl dipeptidyl peptidase 0.0166 0.0712 0.1924
Brugia malayi Calcium binding EGF domain containing protein 0.0043 0.0042 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.2639
Echinococcus granulosus centrin 2 0.0079 0.0239 0.0239
Leishmania major phospholipase c-like protein 0.0079 0.0239 0.0306
Mycobacterium ulcerans proteasome PrcB 0.0156 0.0657 0.2166
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0157 0.066 0.066
Leishmania major calcineurin B subunit, putative 0.0079 0.0239 0.0306
Brugia malayi Pre-SET motif family protein 0.0092 0.0309 0.0309
Echinococcus multilocularis glycoprotein Antigen 5 0.0131 0.0518 0.0518
Loa Loa (eye worm) hypothetical protein 0.0151 0.0631 0.0631
Plasmodium vivax unspecified product 0.0151 0.0631 0.2117
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0151 0.0631 0.0631
Entamoeba histolytica calcium binding family protein 0.0079 0.0239 0.0735
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0151 0.0631 0.2117
Loa Loa (eye worm) hypothetical protein 0.0408 0.2027 0.2027
Giardia lamblia Cathepsin B precursor 0.0151 0.0631 0.1689
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0022 0.0059
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0042
Trypanosoma brucei metacaspase 0.0143 0.0585 0.0749
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0039 0.0022 0.0022
Echinococcus granulosus cathepsin L 0.0327 0.1583 0.1583
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0327 0.1583 0.1583
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.034 0.034
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.008 0.0246 0.0246
Onchocerca volvulus 0.0491 0.2473 0.317
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0062 0.0062
Echinococcus granulosus cathepsin b 0.1877 1 1
Echinococcus granulosus Mastin 0.0131 0.0518 0.0518
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0062 0.0062
Brugia malayi hypothetical protein 0.0041 0.0031 0.0031
Brugia malayi Cathepsin L-like precursor 0.0584 0.2979 0.2979
Echinococcus multilocularis expressed protein 0.0762 0.3948 0.3948
Trypanosoma brucei calpain, putative 0.0157 0.066 0.0846
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0166 0.0712 0.191
Leishmania major protein kinase, putative 0.0079 0.0239 0.0306
Plasmodium vivax aspartyl protease, putative 0.0202 0.0908 0.3047
Leishmania major cathepsin L-like protease 0.0584 0.2979 0.3819
Brugia malayi RNA, U transporter 1 0.0082 0.0252 0.0252
Entamoeba histolytica calpain family cysteine protease, putative 0.0157 0.066 0.2158
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0156 0.0657 0.1764
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0062 0.0062
Echinococcus multilocularis peroxidasin 0.0491 0.2473 0.2473
Brugia malayi EGF-like domain containing protein 0.0043 0.0042 0.0042
Giardia lamblia Cathepsin L-like protease 0.0151 0.0631 0.1689
Entamoeba histolytica cysteine proteinase, putative 0.0327 0.1583 0.5278
Echinococcus granulosus calpain A 0.1462 0.7748 0.7748
Entamoeba histolytica cysteine proteinase, putative 0.0327 0.1583 0.5278
Echinococcus multilocularis protein jagged 1 0.0043 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Loa Loa (eye worm) hypothetical protein 0.0113 0.0425 0.0425
Schistosoma mansoni neuronal calcium sensor 0.0079 0.0239 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Echinococcus multilocularis calumenin 0.008 0.0246 0.0246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.0309 0.0309
Schistosoma mansoni cathepsin F (C01 family) 0.0408 0.2027 0.2027
Echinococcus granulosus geminin 0.0165 0.0707 0.0707
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1877 1 1
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0022 0.0022
Trypanosoma brucei cysteine peptidase C (CPC) 0.0685 0.3528 0.4523
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0022 0.0022
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0113 0.0425 0.0425
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0022 0.0022
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0445 0.0445
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.0631 0.1691
Loa Loa (eye worm) hypothetical protein 0.0099 0.0345 0.0345
Trypanosoma brucei calmodulin, putative 0.008 0.0246 0.0315
Echinococcus multilocularis lamin 0.0053 0.0096 0.0096
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1461 0.7742 0.7742
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0327 0.1583 0.1583
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Trypanosoma cruzi cysteine proteinase, putative 0.0327 0.1583 0.1583
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0156 0.0657 0.2166
Brugia malayi programmed cell death protein 6 0.0079 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0022
Entamoeba histolytica grainin 2 0.0079 0.0239 0.0735
Schistosoma mansoni integrin alpha 0.015 0.0623 0.0623
Echinococcus multilocularis caspase 0.0216 0.0983 0.0983
Schistosoma mansoni cathepsin D (A01 family) 0.0229 0.1054 0.1054
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0195 0.0867 0.0867
Plasmodium falciparum centrin-1 0.0079 0.0239 0.0704
Schistosoma mansoni hypothetical protein 0.0131 0.0518 0.0518
Loa Loa (eye worm) glycogen phosphorylase 0.0108 0.0397 0.0397
Trypanosoma cruzi calmodulin, putative 0.0079 0.0239 0.0239
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0593 0.3031 0.3886
Loa Loa (eye worm) hypothetical protein 0.0166 0.0712 0.0712
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0151 0.0631 0.2117
Giardia lamblia Hypothetical protein 0.0151 0.0631 0.1689
Onchocerca volvulus Cathepsin L homolog 0.0584 0.2979 0.3819
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0175 0.0761 0.0761
Brugia malayi Cadherin domain containing protein 0.0043 0.0042 0.0042
Onchocerca volvulus 0.0131 0.0518 0.0664
Brugia malayi PXA domain containing protein 0.0039 0.0022 0.0022
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0022 0.0022
Entamoeba histolytica cysteine protease, putative 0.0327 0.1583 0.5278
Plasmodium falciparum serine repeat antigen 8 0.0151 0.0631 0.2032
Leishmania major cathepsin L-like protease 0.068 0.3501 0.4488
Echinococcus granulosus neurogenic locus protein delta 0.0043 0.0042 0.0042
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Leishmania major cathepsin L-like protease 0.0584 0.2979 0.3819
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0071 0.0196 0.0196
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0521 0.2639 0.3383
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0046 0.006 0.016
Plasmodium vivax vivapain-2 0.0584 0.2979 1
Echinococcus multilocularis tumor protein p63 0.0675 0.3472 0.3472
Loa Loa (eye worm) hypothetical protein 0.0491 0.2473 0.2473
Leishmania major calpain family cysteine protease-like protein 0.0157 0.066 0.0846
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0584 0.2979 0.7987
Brugia malayi hypothetical protein 0.012 0.0463 0.0463
Echinococcus granulosus calpain 7 C02 family 0.0521 0.2639 0.2639
Toxoplasma gondii centrin 0.0079 0.0239 0.0306
Brugia malayi hypothetical protein 0.0039 0.0022 0.0022
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0685 0.3528 0.3528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.0631 0.1691
Loa Loa (eye worm) trypsin family protein 0.0131 0.0518 0.0518
Trypanosoma cruzi kinesin, putative 0.0364 0.1789 0.1789
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0151 0.0631 0.2032
Leishmania major centrin, putative,caltractin, putative 0.0079 0.0239 0.0306
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Brugia malayi Cell death protein 3 precursor 0.0309 0.1487 0.1487
Echinococcus multilocularis calpain 0.0521 0.2639 0.2639
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0584 0.2979 0.7987
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0309 0.0309
Plasmodium vivax proteasome subunit beta type-5, putative 0.0156 0.0657 0.2204
Echinococcus multilocularis integrin alpha ps 0.0067 0.0174 0.0174
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0022 0.0022
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0071 0.0196 0.0196
Echinococcus multilocularis neurogenic locus notch protein 0.0043 0.0042 0.0042
Brugia malayi Cadherin domain containing protein 0.0043 0.0042 0.0042
Trypanosoma cruzi cysteine peptidase, putative 0.0584 0.2979 0.2979
Giardia lamblia Hypothetical protein 0.008 0.0246 0.0585
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1583 0.4243
Brugia malayi aspartic protease BmAsp-2, identical 0.0041 0.0031 0.0031
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0175 0.0761 0.0761
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042
Loa Loa (eye worm) Notch2 0.0043 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0131 0.0518 0.0518
Leishmania major calmodulin, putative 0.0079 0.0239 0.0306
Echinococcus multilocularis calpain 7 (C02 family) 0.0521 0.2639 0.2639
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0143 0.0585 0.1567
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0151 0.0631 0.1691
Echinococcus granulosus protein jagged 2 0.0043 0.0042 0.0042
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0486 0.1603
Trypanosoma cruzi major cysteine proteinase, putative 0.0247 0.1152 0.1152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.068 0.3501 0.4488
Schistosoma mansoni notch 0.0043 0.0042 0.0042
Leishmania major calmodulin, putative 0.0079 0.0239 0.0306
Onchocerca volvulus 0.0092 0.0309 0.0396
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0096 0.0096
Echinococcus granulosus calpain 0.0521 0.2639 0.2639
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0151 0.0631 0.0631
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1877 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.0631 0.1691
Entamoeba histolytica calmodulin, putative 0.0079 0.0239 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0022 0.0059
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0166 0.0712 0.2335
Loa Loa (eye worm) integrin beta-2 0.0307 0.1476 0.1476
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0327 0.1583 0.2029
Toxoplasma gondii aspartyl protease ASP3 0.0202 0.0908 0.1164
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0079 0.0239 0.0239
Giardia lamblia Cathepsin L precursor 0.0151 0.0631 0.1689
Loa Loa (eye worm) animal heme peroxidase 0.0491 0.2473 0.2473
Onchocerca volvulus 0.0057 0.0117 0.015
Toxoplasma gondii proteasome subunit beta type, putative 0.0156 0.0657 0.0842
Brugia malayi calcium-binding protein 0.0079 0.0239 0.0239
Echinococcus granulosus caspase 3 0.0073 0.0207 0.0207
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0486 0.1603
Trichomonas vaginalis calmodulin, putative 0.0079 0.0239 0.0641
Onchocerca volvulus 0.0131 0.0518 0.0664
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0322 0.1556 0.1556
Echinococcus multilocularis transmembrane protease serine 3 0.0131 0.0518 0.0518
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0634 0.3255 0.3255
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0151 0.0631 0.2117
Onchocerca volvulus 0.0584 0.2979 0.3819
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0151 0.0631 0.0631
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Trypanosoma cruzi caltractin, putative 0.0079 0.0239 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0022 0.0022
Onchocerca volvulus 0.0584 0.2979 0.3819
Onchocerca volvulus 0.0043 0.0042 0.0053
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0584 0.2979 0.2979
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0051 0.0051
Giardia lamblia Cathepsin B precursor 0.0685 0.3528 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0091 0.0091
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0151 0.0631 0.2117
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0079 0.0239 0.0239
Trypanosoma brucei Component of motile flagella 41 0.0079 0.0239 0.0306
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0071 0.0196 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.0631 0.1691
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0239 0.0306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0584 0.2979 0.7987
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0157 0.066 0.0846
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0175 0.0761 0.0761
Echinococcus multilocularis calbindin 32 0.008 0.0246 0.0246
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0041 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0165 0.0707 0.0707
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0486 0.1603
Loa Loa (eye worm) calmodulin-like protein 0.0079 0.0239 0.0239
Echinococcus granulosus protein jagged 1 0.0043 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0042

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 3 umol Inhibition of Topoisomerase 2 ChEMBL. 16242325
Activity (binding) = 3 umol Inhibition of Topoisomerase 2 ChEMBL. 16242325

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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