Detailed information for compound 368824

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 408.305 | Formula: C17H15Cl2N5OS
  • H donors: 3 H acceptors: 3 LogP: 3.99 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNc1nccc(n1)c1ccc(s1)NC(=O)NCc1ccc(cc1Cl)Cl
  • InChi: 1S/C17H15Cl2N5OS/c1-20-16-21-7-6-13(23-16)14-4-5-15(26-14)24-17(25)22-9-10-2-3-11(18)8-12(10)19/h2-8H,9H2,1H3,(H,20,21,23)(H2,22,24,25)
  • InChiKey: BPVVIEDOOWXNGJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens v-akt murine thymoma viral oncogene homolog 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus calcium:calmodulin dependent protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium vivax rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AGC/RSK/P70 protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans likely protein kinase similar to S. cerevisiae YPK2 (YMR104C) Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum Sodium/potassium-transporting ATPase subunit beta-1, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi p70 ribosomal S6 kinase beta Get druggable targets OG5_126635 All targets in OG5_126635
Toxoplasma gondii AGC kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1), related Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K08792 serum/glucocorticoid regulated kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AGC/AKT protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi Protein kinase B Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K04456 RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis rac serine:threonine kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K07390 monothiol glutaredoxin, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase 2, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Giardia lamblia Kinase, AGC PKA Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium yoelii kinase Akt/PKB-related Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium falciparum RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium knowlesi RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus serine threonine protein kinase nrc Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma congolense rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium berghei rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0018 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Trichomonas vaginalis calpain, putative 0.0311 0.0821 0.2291
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0071
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0399 0.1067 0.1067
Loa Loa (eye worm) hypothetical protein 0.0046 0.0082 0.0082
Onchocerca volvulus 0.0145 0.0359 0.0739
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0048 0.0088 0.0447
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0093 0.0212 0.0212
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0002 0.0001
Trypanosoma brucei calpain, putative 0.0311 0.0821 0.1705
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0303 0.0799 0.0797
Entamoeba histolytica grainin 2 0.017 0.0428 0.1559
Schistosoma mansoni hypothetical protein 0.0145 0.0359 0.0358
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0013 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.07 0.1954
Brugia malayi calpain family protein 1 0.2809 0.7799 0.7799
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Echinococcus multilocularis cathepsin L 0.0563 0.1524 0.1524
Trypanosoma brucei calpain-like protein, putative 0.1054 0.2897 0.6027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0055
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0015 0.0015
Echinococcus granulosus caspase 8 0.0105 0.0245 0.0245
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0015 0.0014
Trypanosoma cruzi conserved protein 0.0311 0.0821 0.0819
Brugia malayi proteasome subunit alpha type 6 0.0018 0.0002 0.0002
Echinococcus granulosus endothelin converting enzyme 1 0.0097 0.0224 0.0224
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0013 0.0011
Plasmodium falciparum serine repeat antigen 6 0.0268 0.07 0.2557
Trypanosoma brucei hypothetical protein 0.0311 0.0821 0.1705
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0072 0.0071
Entamoeba histolytica cysteine protease, putative 0.0268 0.07 0.2557
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0015 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0166 0.0417 0.0864
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0071 0.0071
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0268 0.07 0.2557
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0344
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1054 0.2897 0.2896
Loa Loa (eye worm) hypothetical protein 0.0074 0.0158 0.0158
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.009 0.0203 0.0737
Toxoplasma gondii EFHC1, putative 0.0166 0.0417 0.0864
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0055 0.0054
Echinococcus multilocularis caspase 8 0.0105 0.0245 0.0245
Trypanosoma cruzi I/6 autoantigen, putative 0.0166 0.0417 0.0415
Onchocerca volvulus 0.1755 0.4854 1
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Trichomonas vaginalis calmodulin, putative 0.0166 0.0417 0.1161
Echinococcus multilocularis calbindin 32 0.0169 0.0425 0.0425
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0064 0.0146
Brugia malayi calcium-binding protein 0.0166 0.0417 0.0417
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0042 0.007 0.007
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0019 0.0019
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0082 0.0082
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0268 0.07 0.07
Giardia lamblia Proteasome subunit beta type 1 0.007 0.0147 0.0406
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0025 0.0023 0.0023
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0019 0.0035
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0013 0.003
Toxoplasma gondii PAN domain-containing protein 0.003 0.0037 0.0072
Echinococcus granulosus cathepsin l cysteine peptidase 0.0995 0.2733 0.2733
Entamoeba histolytica calcium binding family protein 0.0166 0.0417 0.152
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0197 0.0545
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0049 0.009 0.0089
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0034 0.0049 0.0098
Brugia malayi prolyl oligopeptidase family protein 0.1738 0.4806 0.4806
Leishmania major cytochrome p450-like protein 0.0035 0.0051 0.0101
Entamoeba histolytica calmodulin, putative 0.0166 0.0417 0.152
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0013 0.0013
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0709 0.1932 0.4017
Echinococcus granulosus histone deacetylase 3 0.0087 0.0197 0.0197
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0038 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0074 0.0158 0.0158
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0015 0.0015
Toxoplasma gondii hypothetical protein 0.003 0.0037 0.0072
Trypanosoma brucei calpain-like protein, putative 0.1054 0.2897 0.6027
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0268 0.07 0.1954
Giardia lamblia Cathepsin L precursor 0.0268 0.07 0.1954
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0709 0.1932 0.193
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0073 0.0071
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0051 0.0051
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2975 0.8263 0.8263
Toxoplasma gondii aspartyl protease ASP3 0.0204 0.0522 0.1082
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0268 0.07 0.1954
Brugia malayi 20S proteasome alpha5 subunit 0.0018 0.0002 0.0002
Brugia malayi Probable ATP-dependent helicase DHX35 0.0064 0.013 0.013
Giardia lamblia Cathepsin L-like protease 0.0268 0.07 0.1954
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0018 0.0002 0.0001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0015 0.0014
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.009 0.0203 0.0202
Trypanosoma cruzi metacaspase 5, putative 0.0105 0.0245 0.0243
Giardia lamblia Alanyl dipeptidyl peptidase 0.0208 0.0535 0.149
Toxoplasma gondii ABC1 family protein 0.0037 0.0055 0.011
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.007 0.0069
Plasmodium falciparum plasmepsin VII 0.0042 0.007 0.025
Schistosoma mansoni calpain-2 (C02 family) 0.0311 0.0821 0.082
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0042 0.007 0.007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0015 0.0015
Entamoeba histolytica cysteine proteinase, putative 0.07 0.1909 0.6983
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Leishmania major cysteine peptidase A (CPA) 0.0995 0.2733 0.5684
Trypanosoma cruzi cruzipain precursor, putative 0.1099 0.3023 0.3022
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0055 0.0126
Loa Loa (eye worm) hypothetical protein 0.0187 0.0474 0.0474
Schistosoma mansoni hypothetical protein 0.0025 0.0024 0.0023
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0071 0.0071
Echinococcus multilocularis expressed protein 0.0825 0.2256 0.2256
Brugia malayi Cathepsin L-like precursor 0.0995 0.2733 0.2733
Plasmodium vivax hypothetical protein, conserved 0.0169 0.0425 0.146
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.0087
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0268 0.07 0.2557
Entamoeba histolytica cysteine proteinase 1, putative 0.0563 0.1524 0.5575
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0025 0.0022 0.0022
Leishmania major cathepsin L-like protease 0.0995 0.2733 0.5684
Mycobacterium leprae probable zinc metalloprotease 0.0097 0.0224 0.1153
Echinococcus granulosus cathepsin L 0.0563 0.1524 0.1524
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0311 0.0821 0.0819
Leishmania major centrin, putative,caltractin, putative 0.0166 0.0417 0.0864
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0097 0.0223 0.0461
Echinococcus granulosus caspase 2 0.0327 0.0865 0.0865
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0995 0.2733 1
Echinococcus multilocularis nervana 2 0.0025 0.0022 0.0022
Giardia lamblia Histone deacetylase 0.0087 0.0197 0.0545
Loa Loa (eye worm) EF hand family protein 0.0166 0.0417 0.0417
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0018 0.0002 0.0002
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.007 0.0147 0.0302
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Entamoeba histolytica cysteine protease, putative 0.0268 0.07 0.2557
Schistosoma mansoni flap endonuclease-1 0.0024 0.002 0.0019
Echinococcus multilocularis hypothetical protein 0.1054 0.2897 0.2897
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Brugia malayi beta-lactamase 0.0037 0.0055 0.0055
Onchocerca volvulus 0.0166 0.0417 0.0859
Brugia malayi hypothetical protein 0.0145 0.0359 0.0359
Entamoeba histolytica cysteine proteinase, putative 0.0563 0.1524 0.5575
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0474 0.0474
Leishmania major cathepsin L-like protease 0.0995 0.2733 0.5684
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1297 0.3577 0.3575
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0064 0.0226
Loa Loa (eye worm) hypothetical protein 0.0145 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Loa Loa (eye worm) PAS-3 protein 0.0018 0.0002 0.0002
Brugia malayi p70 ribosomal S6 kinase beta 0.0038 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0166 0.0417 0.0416
Brugia malayi ecdysteroid receptor 0.0022 0.0015 0.0015
Schistosoma mansoni mitochondrial solute carrier 0.0166 0.0417 0.0416
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0034 0.0049 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0535 0.149
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0071 0.007
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0311 0.0821 0.1705
Loa Loa (eye worm) hypothetical protein 0.0074 0.0158 0.0158
Schistosoma mansoni calpain (C02 family) 0.1054 0.2897 0.2897
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0055 0.0126
Loa Loa (eye worm) beta-lactamase 0.0037 0.0055 0.0055
Echinococcus multilocularis survival motor neuron protein 1 0.0258 0.0674 0.0674
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0073 0.0073
Schistosoma mansoni calpain-7 (C02 family) 0.1057 0.2906 0.2905
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.009 0.0203 0.0203
Echinococcus granulosus histone deacetylase 6 0.0098 0.0227 0.0227
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0055 0.0126
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0071 0.007
Brugia malayi Flap endonuclease-1 0.0027 0.0027 0.0027
Trichomonas vaginalis calmodulin, putative 0.0166 0.0417 0.1161
Entamoeba histolytica cysteine proteinase 2 0.0563 0.1524 0.5575
Echinococcus granulosus cysteine protease 0.0563 0.1524 0.1524
Giardia lamblia Cathepsin B precursor 0.0268 0.07 0.1954
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0295 0.0777 0.0777
Onchocerca volvulus 0.0032 0.0041 0.0085
Schistosoma mansoni ef hand domain family member A2 0.0166 0.0417 0.0416
Brugia malayi Cathepsin L-like precursor 0.0295 0.0777 0.0777
Onchocerca volvulus 0.07 0.1909 0.3932
Giardia lamblia Cysteine protease 0.0268 0.07 0.1954
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0268 0.07 0.1954
Trichomonas vaginalis calpain, putative 0.0311 0.0821 0.2291
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0223 0.0223
Schistosoma mansoni peroxidasin 0.0169 0.0426 0.0425
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0268 0.07 0.1954
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0268 0.07 0.2412
Trypanosoma brucei proteasome beta 6 subunit 0.007 0.0147 0.0302
Echinococcus granulosus proteasome subunit beta type 6 0.0018 0.0002 0.0002
Toxoplasma gondii microneme protein MIC17C 0.003 0.0037 0.0072
Echinococcus multilocularis programmed cell death protein 0.017 0.0428 0.0428
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0325 0.0325
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Brugia malayi peptidase family M13 containing protein 0.0024 0.0019 0.0019
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0037 0.0037
Chlamydia trachomatis glycogen phosphorylase 0.0112 0.0266 0.5
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0043 0.0072 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Echinococcus multilocularis cysteine protease 0.0995 0.2733 0.2733
Plasmodium falciparum plasmepsin VIII, putative 0.0042 0.007 0.025
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0097 0.0224 0.0527
Brugia malayi CXXC zinc finger family protein 0.0032 0.0041 0.0041
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0268 0.07 0.07
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0995 0.2733 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0015 0.0015
Onchocerca volvulus Legumain homolog 0.0148 0.0367 0.0757
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0055 0.011
Leishmania major hypothetical protein, conserved 0.0166 0.0417 0.0864
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0071 0.0071
Plasmodium falciparum cysteine repeat modular protein 1 0.0046 0.0082 0.0294
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0015 0.0015
Onchocerca volvulus 0.003 0.0037 0.0075
Trypanosoma brucei antigen, putative 0.1054 0.2897 0.6027
Loa Loa (eye worm) hypothetical protein 0.2809 0.7799 0.7799
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0169 0.0425 0.0424
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0563 0.1524 0.1524
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0051 0.0049
Entamoeba histolytica hypothetical protein 0.0268 0.07 0.2557
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Loa Loa (eye worm) proteasome subunit beta type 3 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0126 0.0126
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Brugia malayi beta-lactamase family protein 0.0037 0.0055 0.0055
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0021 0.0013 0.003
Onchocerca volvulus 0.003 0.0037 0.0075
Brugia malayi Protein kinase domain containing protein 0.0046 0.0082 0.0082
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0071 0.0071
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0166 0.0417 0.0415
Echinococcus granulosus cathepsin b 0.3597 1 1
Echinococcus granulosus caspase 0.0245 0.0638 0.0638
Brugia malayi steroid hormone receptor 0.0022 0.0015 0.0015
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0018 0.0002 0.0001
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0027 0.0053
Trypanosoma brucei histone deacetylase 2 0.0042 0.007 0.0143
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0547 0.1481 0.3051
Onchocerca volvulus 0.0053 0.01 0.0206
Trypanosoma cruzi metacaspase 5, putative 0.0105 0.0245 0.0243
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0311 0.0821 0.2291
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0311 0.0821 0.0819
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0268 0.07 0.1954
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0709 0.1932 0.193
Schistosoma mansoni memapsin-2 (A01 family) 0.0499 0.1347 0.1346
Schistosoma mansoni caspase-7 (C14 family) 0.0245 0.0638 0.0637
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0268 0.07 0.07
Brugia malayi cathepsin L-like cysteine proteinase 0.0268 0.07 0.07
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0027 0.0088
Brugia malayi Cytochrome P450 family protein 0.0035 0.0051 0.0051
Plasmodium vivax hypothetical protein, conserved 0.0208 0.0535 0.184
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0071 0.0071
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0311 0.0821 0.0819
Brugia malayi Blistered cuticle protein 3 0.0169 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0019
Brugia malayi histone deacetylase 3 (HD3) 0.0087 0.0197 0.0197
Leishmania major calcineurin B subunit, putative 0.0166 0.0417 0.0864
Echinococcus multilocularis cpg binding protein 0.0034 0.0046 0.0046
Giardia lamblia Cathepsin L precursor 0.0268 0.07 0.1954
Brugia malayi MH2 domain containing protein 0.0124 0.03 0.03
Onchocerca volvulus 0.003 0.0037 0.0075
Plasmodium vivax vivapain-3 0.0563 0.1524 0.5258
Brugia malayi hypothetical protein 0.0042 0.0071 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0563 0.1524 0.4259
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0268 0.07 0.2557
Echinococcus granulosus neurocalcin 0.0166 0.0417 0.0417
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.6027
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0147 0.0406
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0222 0.0573 0.0573
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3597 1 1
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0018 0.0002 0.0002
Entamoeba histolytica protein kinase, putative 0.0038 0.0058 0.0205
Echinococcus granulosus dnaJ subfamily B 0.0451 0.1214 0.1214
Giardia lamblia Hypothetical protein 0.0213 0.0547 0.1525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0563 0.1524 0.3168
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0295 0.0777 0.0777
Entamoeba histolytica histone deacetylase, putative 0.0087 0.0197 0.0714
Echinococcus granulosus cathepsin l1 0.07 0.1909 0.1909
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0166 0.0417 0.152
Plasmodium vivax histone deacetylase, putative 0.0098 0.0227 0.0777
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Echinococcus multilocularis histone deacetylase 1 0.0087 0.0197 0.0197
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0325 0.0766
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0015 0.0015
Trypanosoma brucei calpain, putative 0.0311 0.0821 0.1705
Trichomonas vaginalis conserved hypothetical protein 0.0311 0.0821 0.2291
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0114 0.0271 0.027
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0018 0.0003 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0097 0.0223 0.0223
Echinococcus granulosus inhibitor of apoptosis protein 0.0187 0.0474 0.0474
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0268 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0166 0.0417 0.0417
Trypanosoma brucei centrin, putative 0.0166 0.0417 0.0864
Onchocerca volvulus Cathepsin L homolog 0.0995 0.2733 0.5629
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus multilocularis Glycosyl transferase, family 35 0.0112 0.0266 0.0266
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0021 0.0013 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0535 0.0533
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1054 0.2897 0.6027
Brugia malayi Kringle domain containing protein 0.0046 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0145 0.0359 0.0358
Plasmodium falciparum cysteine proteinase falcipain 3 0.0995 0.2733 1
Echinococcus granulosus tumor protein p63 0.0373 0.0995 0.0995
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0027 0.0093
Brugia malayi Calmodulin-like protein 0.0166 0.0417 0.0417
Trypanosoma brucei centrin, putative 0.0166 0.0417 0.0864
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0547 0.1481 0.1481
Onchocerca volvulus 0.0046 0.0082 0.017
Plasmodium falciparum plasmepsin I 0.0042 0.007 0.025
Plasmodium falciparum serine repeat antigen 4 0.0268 0.07 0.2557
Toxoplasma gondii proteasome subunit beta type, putative 0.009 0.0203 0.0419
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0166 0.0417 0.152
Schistosoma mansoni cathepsin F (C01 family) 0.0995 0.2733 0.2732
Schistosoma mansoni cathepsin S (C01 family) 0.0268 0.07 0.07
Leishmania major hypothetical protein, conserved 0.0311 0.0821 0.1705
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.03 0.03
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0268 0.07 0.2412
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.03 0.03
Brugia malayi cathepsin F-like cysteine proteinase 0.0295 0.0777 0.0777
Entamoeba histolytica cysteine protease, putative 0.0268 0.07 0.2557
Echinococcus multilocularis histone deacetylase 0.0098 0.0227 0.0227
Echinococcus granulosus calpain 7 C02 family 0.1054 0.2897 0.2897
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0071 0.0071
Entamoeba histolytica GPI-anchor transamidase, putative 0.0034 0.0049 0.0172
Onchocerca volvulus Cathepsin L homolog 0.0268 0.07 0.1443
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0051 0.0049
Giardia lamblia Cathepsin L-like protease 0.0268 0.07 0.1954
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0015 0.0031
Entamoeba histolytica protein kinase, putative 0.004 0.0065 0.023
Echinococcus multilocularis acylamino acid releasing enzyme 0.0208 0.0535 0.0535
Schistosoma mansoni cathepsin F (C01 family) 0.07 0.1909 0.1908
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0071
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0244 0.0244
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0303 0.0799 0.0799
Echinococcus granulosus acylamino acid releasing enzyme 0.0208 0.0535 0.0535
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0064 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0268 0.07 0.1954
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0021 0.0013 0.0013
Giardia lamblia Cysteine protease 0.0268 0.07 0.1954
Trichomonas vaginalis AGC family protein kinase 0.004 0.0065 0.0176
Loa Loa (eye worm) histone deacetylase 3 0.0087 0.0197 0.0197
Echinococcus granulosus EF hand domain containing family member A2 0.0166 0.0417 0.0417
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Echinococcus multilocularis neuronal calcium sensor 0.0166 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0145 0.0359 0.0359
Brugia malayi hypothetical protein 0.0042 0.007 0.007
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Echinococcus multilocularis proteasome (prosome, macropain) 0.009 0.0203 0.0203
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0041 0.0041
Entamoeba histolytica cysteine proteinase, putative 0.0563 0.1524 0.5575
Onchocerca volvulus 0.003 0.0037 0.0075
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Brugia malayi Angiotensin-converting enzyme family protein 0.0599 0.1626 0.1626
Echinococcus granulosus tissue type plasminogen activator 0.0046 0.0082 0.0082
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1738 0.4806 0.4806
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0055 0.0055
Brugia malayi gamma-secretase subunit aph-1 0.0254 0.0662 0.0662
Trypanosoma cruzi metacaspase, putative 0.0105 0.0245 0.0243
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0018 0.0002 0.0001
Trichomonas vaginalis glycogen phosphorylase, putative 0.0112 0.0266 0.0739
Plasmodium falciparum histone deacetylase 1 0.0087 0.0197 0.0714
Plasmodium vivax proteasome subunit beta type-1, putative 0.007 0.0147 0.0502
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0599 0.1626 0.1626
Schistosoma mansoni calpain-7 (C02 family) 0.1057 0.2906 0.2905
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0547 0.1481 0.148
Echinococcus granulosus proteasome prosome macropain 0.009 0.0203 0.0203
Trypanosoma brucei prolyl oligopeptidase, putative 0.0709 0.1932 0.4017
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0073 0.0199
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0015 0.0015
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0071 0.007
Schistosoma mansoni hypothetical protein 0.0046 0.0082 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0071 0.0193
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0055 0.0275
Leishmania major calmodulin, putative 0.0166 0.0417 0.0864
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.3597 1 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0002 0.0001
Plasmodium falciparum plasmepsin II 0.0042 0.007 0.025
Onchocerca volvulus 0.003 0.0037 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0245 0.068
Echinococcus multilocularis enteropeptidase 0.0145 0.0359 0.0359
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0024 0.0023
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0268 0.07 0.1954
Mycobacterium tuberculosis Conserved protein 0.0213 0.0547 0.1291
Toxoplasma gondii PAN domain-containing protein 0.003 0.0037 0.0072
Entamoeba histolytica grainin, putative 0.0169 0.0425 0.1548
Loa Loa (eye worm) hypothetical protein 0.0105 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0013 0.0013
Loa Loa (eye worm) histone deacetylase 1 0.0087 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0055
Plasmodium falciparum serine repeat antigen 7 0.0268 0.07 0.2557
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0995 0.2733 0.2733
Echinococcus granulosus histone lysine methyltransferase setb 0.0097 0.0223 0.0223
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0197 0.0545
Schistosoma mansoni cpg binding protein 0.0034 0.0046 0.0046
Brugia malayi Peptidase family M13 containing protein 0.0097 0.0224 0.0224
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0019 0.0047
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0018 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Toxoplasma gondii cathepsin CPC2 0.0268 0.07 0.1454
Leishmania major cathepsin L-like protease 0.1099 0.3023 0.6288
Toxoplasma gondii proteasome subunit beta type 1, putative 0.007 0.0147 0.0302
Echinococcus granulosus microtubule associated protein 2 0.1525 0.4212 0.4212
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Mycobacterium ulcerans hypothetical protein 0.0213 0.0547 0.2825
Brugia malayi Proteasome subunit alpha type 7-1 0.0018 0.0002 0.0002
Schistosoma mansoni microtubule-associated protein tau 0.1525 0.4212 0.4211
Brugia malayi hypothetical protein 0.0095 0.0217 0.0217
Schistosoma mansoni centrin 0.0166 0.0417 0.0416
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0268 0.07 0.2557
Onchocerca volvulus 0.0037 0.0055 0.0113
Echinococcus multilocularis nervana 2 0.0025 0.0022 0.0022
Plasmodium falciparum serine repeat antigen 1 0.0268 0.07 0.2557
Onchocerca volvulus 0.0145 0.0359 0.0739
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0019 0.0035
Onchocerca volvulus 0.0995 0.2733 0.5629
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0229 0.0227
Brugia malayi Pre-SET motif family protein 0.0671 0.1827 0.1827
Giardia lamblia Hypothetical protein 0.0268 0.07 0.1954
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0268 0.07 0.1954
Echinococcus granulosus proteasome subunit beta t family 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Brugia malayi nuclear hormone receptor 0.0022 0.0015 0.0015
Brugia malayi prolyl oligopeptidase family protein 0.0208 0.0535 0.0535
Mycobacterium ulcerans proteasome PrcB 0.009 0.0203 0.1042
Trypanosoma cruzi major cysteine proteinase, putative 0.0372 0.0991 0.0989
Giardia lamblia Cathepsin B precursor 0.0268 0.07 0.1954
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Loa Loa (eye worm) calpain 5 0.0743 0.2029 0.2029
Trichomonas vaginalis calcium binding protein, putative 0.0166 0.0417 0.1161
Plasmodium falciparum flap endonuclease 1 0.0027 0.0027 0.0093
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0073 0.0073
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0311 0.0821 0.0819
Plasmodium vivax serine-repeat antigen (SERA) 0.0268 0.07 0.2412
Plasmodium falciparum serine repeat antigen 8 0.0268 0.07 0.2557
Brugia malayi cathepsin Z-like cysteine proteinase 0.0268 0.07 0.07
Entamoeba histolytica cysteine protease, putative 0.0995 0.2733 1
Brugia malayi PXA domain containing protein 0.0042 0.0071 0.0071
Echinococcus granulosus glycogen phosphorylase 0.0112 0.0266 0.0266
Onchocerca volvulus 0.003 0.0037 0.0075
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0709 0.1932 1
Plasmodium vivax vivapain-2 0.0995 0.2733 0.9431
Echinococcus multilocularis proteasome subunit alpha type 2 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0245 0.068
Echinococcus granulosus peroxidasin 0.0169 0.0426 0.0426
Echinococcus multilocularis glycogen phosphorylase 0.0112 0.0266 0.0266
Giardia lamblia Cathepsin L precursor 0.0268 0.07 0.1954
Loa Loa (eye worm) hypothetical protein 0.0268 0.07 0.07
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0055 0.0148
Loa Loa (eye worm) calpain D 0.0311 0.0821 0.0821
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0109
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.007 0.007
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0019 0.0017
Onchocerca volvulus 0.0042 0.007 0.0145
Loa Loa (eye worm) fibroinase 0.0995 0.2733 0.2733
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.007 0.0147 0.0147
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0268 0.07 0.07
Echinococcus multilocularis prolyl endopeptidase 0.1738 0.4806 0.4806
Trypanosoma cruzi cysteine peptidase, putative 0.1099 0.3023 0.3022
Leishmania major cathepsin L-like protease 0.0995 0.2733 0.5684
Echinococcus granulosus histone deacetylase 7 0.0098 0.0227 0.0227
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0208 0.0535 0.1109
Echinococcus multilocularis rac serine:threonine kinase 0.0028 0.003 0.003
Onchocerca volvulus 0.0097 0.0223 0.046
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Plasmodium vivax centrin-1, putative 0.0166 0.0417 0.1433
Brugia malayi hypothetical protein 0.0167 0.0419 0.0419
Plasmodium vivax serine-repeat antigen (SERA) 0.0268 0.07 0.2412
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0311 0.0821 0.0819
Brugia malayi Papain family cysteine protease containing protein 0.0268 0.07 0.07
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1054 0.2897 0.2896
Entamoeba histolytica glycogen phosphorylase, putative 0.0112 0.0266 0.0967
Trichomonas vaginalis AGC family protein kinase 0.004 0.0065 0.0176
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0015 0.0015
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.0426 0.0426
Loa Loa (eye worm) glycogen phosphorylase 0.0112 0.0266 0.0266
Onchocerca volvulus 0.0169 0.0426 0.0878
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0197 0.0195
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0015 0.0015
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0148 0.0367 0.1022
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0049 0.0131
Trypanosoma brucei kinesin, putative 0.0743 0.2029 0.4219
Brugia malayi Cathepsin L-like precursor 0.07 0.1909 0.1909
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2975 0.8263 0.8263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0015 0.0015
Trypanosoma cruzi oligopeptidase b 0.0709 0.1932 0.193
Loa Loa (eye worm) hypothetical protein 0.2066 0.5722 0.5722
Toxoplasma gondii PAN domain-containing protein 0.003 0.0037 0.0072
Brugia malayi hypothetical protein 0.0042 0.007 0.007
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0025 0.0023 0.0023
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0268 0.07 0.1954
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Mycobacterium leprae proteasome (beta subunit) PrcB 0.009 0.0203 0.1042
Brugia malayi Proteasome subunit alpha type 1 0.0018 0.0002 0.0002
Entamoeba histolytica proteasome subunit beta type 1, putative 0.007 0.0147 0.0532
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0197 0.0545
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Echinococcus granulosus proteasome subunit alpha type 2 0.0018 0.0002 0.0002
Loa Loa (eye worm) ctsf protein 0.0995 0.2733 0.2733
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0227 0.0226
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0147 0.0145
Echinococcus multilocularis glycoprotein Antigen 5 0.0145 0.0359 0.0359
Schistosoma mansoni neprilysin-2 (M13 family) 0.0049 0.009 0.0089
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2809 0.7799 0.7798
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0073 0.0148
Schistosoma mansoni hemoglobinase (C13 family) 0.0148 0.0367 0.0367
Schistosoma mansoni hypothetical protein 0.0166 0.0417 0.0416
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0018 0.0002 0.0001
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0019 0.0058
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0325 0.0325
Onchocerca volvulus 0.0145 0.0359 0.0739
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Entamoeba histolytica hypothetical protein 0.0042 0.0071 0.0253
Mycobacterium leprae Conserved hypothetical protein 0.0213 0.0547 0.2825
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0071 0.0071
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0042 0.007 0.007
Onchocerca volvulus Neurogenic locus notch homolog 0.0017 0.0001 0.0002
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0229 0.0473
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0187 0.0474 0.0474
Echinococcus granulosus proteasome prosome macropain subunit beta 0.007 0.0147 0.0147
Plasmodium vivax aspartyl protease, putative 0.0204 0.0522 0.1796
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0018 0.0002 0.0002
Echinococcus multilocularis calmodulin 0.0166 0.0417 0.0417
Echinococcus granulosus histone deacetylase 1 0.0087 0.0197 0.0197
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0358
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Loa Loa (eye worm) hypothetical protein 0.0097 0.0223 0.0223
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0021 0.0013 0.0013
Toxoplasma gondii hypothetical protein 0.003 0.0037 0.0072
Entamoeba histolytica cysteine protease, putative 0.0268 0.07 0.2557
Brugia malayi carbohydrate phosphorylase 0.0112 0.0266 0.0266
Loa Loa (eye worm) AGC/AKT protein kinase 0.004 0.0065 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0071 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0015 0.0015
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0018 0.0002 0.0001
Trypanosoma brucei Calpain-like protein CALP1.3 0.0311 0.0821 0.1705
Trichomonas vaginalis esterase, putative 0.0037 0.0055 0.0148
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.009 0.0089
Schistosoma mansoni glycogen phosphorylase 0.0112 0.0266 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0071 0.0071
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0025 0.0023 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1054 0.2897 0.2896
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0019 0.0019
Echinococcus multilocularis EF hand domain containing family member A2 0.0169 0.0425 0.0425
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0311 0.0821 0.0819
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0055 0.0126
Echinococcus granulosus serine threonine protein kinase nrc 0.0025 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0268 0.07 0.1954
Plasmodium vivax unspecified product 0.0563 0.1524 0.5258
Loa Loa (eye worm) zinc metallopeptidase 4 0.0024 0.0019 0.0019
Plasmodium falciparum plasmepsin VI 0.0042 0.007 0.025
Echinococcus granulosus beta-adrenergic receptor kinase 0.0043 0.0072 0.0072
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0055 0.0275
Leishmania major calpain protease-like protein 0.0311 0.0821 0.1705
Brugia malayi histone deacetylase 11 0.0042 0.007 0.007
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0563 0.1524 0.1524
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Loa Loa (eye worm) prolyl oligopeptidase 0.0547 0.1481 0.1481
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0027 0.0027
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0013 0.0011
Onchocerca volvulus 0.0169 0.0425 0.0875
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0055 0.0055
Onchocerca volvulus Glycogen phosphorylase homolog 0.0112 0.0266 0.0548
Echinococcus multilocularis caspase 3 0.0141 0.0346 0.0346
Echinococcus multilocularis centrin 2 0.0166 0.0417 0.0417
Trypanosoma cruzi cysteine proteinase, putative 0.0563 0.1524 0.1523
Toxoplasma gondii microneme protein MIC17B 0.003 0.0037 0.0072
Loa Loa (eye worm) calpain family protein 1 0.2066 0.5722 0.5722
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Echinococcus multilocularis microtubule associated protein 2 0.1525 0.4212 0.4212
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0311 0.0821 0.0819
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0015 0.0015
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0229 0.0227
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0187 0.0474 0.0474
Echinococcus granulosus expressed protein 0.0825 0.2256 0.2256
Trichomonas vaginalis calmodulin, putative 0.0169 0.0425 0.1183
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Giardia lamblia Serine peptidase, putative 0.0021 0.0013 0.003
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0037 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0015 0.0015
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0015 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Loa Loa (eye worm) prolyl oligopeptidase 0.0208 0.0535 0.0535
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Brugia malayi calpain D 0.0311 0.0821 0.0821
Trypanosoma brucei Calpain-like protein 1.2 0.0311 0.0821 0.1705
Trypanosoma cruzi centrin-3 0.017 0.0428 0.0426
Giardia lamblia Cathepsin L precursor 0.0268 0.07 0.1954
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Entamoeba histolytica prolyl oligopeptidase family protein 0.0208 0.0535 0.1951
Onchocerca volvulus Prolyl endopeptidase homolog 0.1738 0.4806 0.9902
Loa Loa (eye worm) hypothetical protein 0.0064 0.013 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0563 0.1524 0.3168
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0145 0.0359 0.0359
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0535 0.0533
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0015 0.0015
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1755 0.4854 0.4854
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0064 0.0064
Echinococcus granulosus proteasome subunit beta type 7 0.0018 0.0002 0.0002
Brugia malayi Cytochrome P450 family protein 0.0035 0.0051 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0223 0.0223
Schistosoma mansoni glycogen phosphorylase 0.0112 0.0266 0.0265
Entamoeba histolytica protein kinase 2, putative 0.0025 0.0023 0.0076
Echinococcus multilocularis proteasome subunit alpha type 6 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0169 0.0426 0.0878
Loa Loa (eye worm) hypothetical protein 0.07 0.1909 0.1909
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0064 0.0172
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Leishmania major calmodulin, putative 0.0166 0.0417 0.0864
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0325 0.0673
Schistosoma mansoni hypothetical protein 0.0025 0.0024 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Echinococcus multilocularis caspase 2 0.0327 0.0865 0.0865
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0055 0.0148
Leishmania major metacaspase, putative 0.0105 0.0245 0.0506
Brugia malayi proteasome subunit alpha type 3 0.0018 0.0002 0.0002
Onchocerca volvulus Dual oxidase homolog 0.0169 0.0426 0.0878
Schistosoma mansoni caspase-7 (C14 family) 0.0327 0.0865 0.0864
Onchocerca volvulus Chorion peroxidase homolog 0.0169 0.0426 0.0878
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0015 0.0015
Schistosoma mansoni inhibitor of apoptosis protein 0.0187 0.0474 0.0474
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0071 0.0071
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1054 0.2897 0.2896
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Onchocerca volvulus 0.0995 0.2733 0.5629
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0071 0.0071
Trypanosoma brucei Component of motile flagella 41 0.0166 0.0417 0.0864
Echinococcus multilocularis inhibitor of apoptosis protein 0.0187 0.0474 0.0474
Trichomonas vaginalis AGC family protein kinase 0.004 0.0065 0.0176
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0027 0.0071
Trichomonas vaginalis calmodulin, putative 0.017 0.0428 0.1191
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0019 0.0062
Brugia malayi Cathepsin L-like cysteine proteinase 0.07 0.1909 0.1909
Brugia malayi aspartic protease BmAsp-1, identical 0.0042 0.007 0.007
Echinococcus multilocularis Transglutaminase 0.0213 0.0547 0.0547
Entamoeba histolytica hypothetical protein, conserved 0.0169 0.0425 0.1548
Schistosoma mansoni coup transcription factor 0.0022 0.0015 0.0014
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.003 0.0028
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0148 0.0367 0.1022
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.0071 0.0144
Trichomonas vaginalis calcium binding protein, putative 0.0166 0.0417 0.1161
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0042 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Brugia malayi prolyl oligopeptidase family protein 0.0303 0.0799 0.0799
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Echinococcus granulosus EF hand domain containing family member A2 0.0169 0.0425 0.0425
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.007 0.0143
Echinococcus granulosus neuronal calcium sensor 0.0166 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Trypanosoma cruzi cysteine proteinase, putative 0.0563 0.1524 0.1523
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0245 0.0638 0.0638
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0148 0.0367 0.1022
Echinococcus granulosus proteasome subunit alpha type 6 0.0018 0.0002 0.0002
Trichomonas vaginalis calcium binding proteins, putative 0.0166 0.0417 0.1161
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.0426 0.0426
Mycobacterium ulcerans transglutaminase family protein 0.0213 0.0547 0.2825
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0037 0.0037
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Leishmania major hypothetical protein, conserved 0.0169 0.0425 0.088
Brugia malayi Trypsin family protein 0.0145 0.0359 0.0359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.07 0.1909 0.5334
Giardia lamblia Cysteine protease 0.0268 0.07 0.1954
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0064 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0345 0.0345
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.01 0.01
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0015 0.0015
Brugia malayi Cathepsin L-like precursor 0.0995 0.2733 0.2733
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0311 0.0821 0.2291
Mycobacterium ulcerans hypothetical protein 0.0145 0.0359 0.1847
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0227 0.0227
Echinococcus granulosus Mastin 0.0145 0.0359 0.0359
Echinococcus granulosus calcium uptake protein 1 0.0169 0.0425 0.0425
Leishmania major calmodulin-like protein 0.0166 0.0417 0.0864
Giardia lamblia Kinase, AGC PKA 0.0025 0.0023 0.0058
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0018 0.0002 0.0002
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0258 0.0674 0.0674
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0088 0.0316
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0325 0.1676
Echinococcus granulosus cathepsin L cysteine protease 0.0563 0.1524 0.1524
Plasmodium falciparum plasmepsin V 0.0042 0.007 0.025
Brugia malayi fibroinase precursor 0.0268 0.07 0.07
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0268 0.07 0.07
Plasmodium vivax metacaspase 1, putative 0.0105 0.0245 0.0839
Plasmodium vivax hypothetical protein, conserved 0.0105 0.0245 0.0839
Loa Loa (eye worm) hypothetical protein 0.0042 0.007 0.007
Trichomonas vaginalis calmodulin, putative 0.0166 0.0417 0.1161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0268 0.07 0.1954
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Onchocerca volvulus Cathepsin L homolog 0.0995 0.2733 0.5629
Leishmania major cathepsin L-like protease 0.0995 0.2733 0.5684
Brugia malayi Cathepsin L-like precursor 0.0995 0.2733 0.2733
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0145 0.0359 0.0359
Onchocerca volvulus 0.0037 0.0055 0.0113
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.007 0.0069
Echinococcus granulosus transmembrane protease serine 3 0.0145 0.0359 0.0359
Schistosoma mansoni hypothetical protein 0.0187 0.0474 0.0474
Trypanosoma brucei oligopeptidase b 0.0709 0.1932 0.4017
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0073 0.0246
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Entamoeba histolytica calmodulin, putative 0.0166 0.0417 0.152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1297 0.3577 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0055 0.0275
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0358
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0024 0.0019 0.0018
Schistosoma mansoni neuronal calcium sensor 0.0166 0.0417 0.0416
Loa Loa (eye worm) peptidase family M13 containing protein 0.0072 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0208 0.0535 0.0535
Onchocerca volvulus 0.0167 0.0419 0.0863
Toxoplasma gondii AGC kinase 0.0038 0.0058 0.0117
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0325 0.1676
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0223 0.0223
Trypanosoma brucei rac serine-threonine kinase, putative 0.004 0.0065 0.0131
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0073 0.0071
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0166 0.0417 0.1161
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Plasmodium falciparum serine repeat antigen 3 0.0268 0.07 0.2557
Echinococcus multilocularis geminin 0.0169 0.0426 0.0426
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0051 0.0252
Onchocerca volvulus 0.0222 0.0573 0.118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0268 0.07 0.1954
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0015 0.0015
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0268 0.07 0.2412
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0018 0.0002 0.0002
Toxoplasma gondii PAN domain-containing protein 0.003 0.0037 0.0072
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Giardia lamblia Cathepsin B precursor 0.0268 0.07 0.1954
Echinococcus multilocularis endothelin converting enzyme 1 0.0097 0.0224 0.0224
Trypanosoma brucei calpain-like protein, putative 0.1054 0.2897 0.6027
Trypanosoma brucei metacaspase MCA3 0.0105 0.0245 0.0506
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0064 0.0226
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0021 0.0013 0.0012
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0071 0.0071
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0303 0.0799 0.1658
Loa Loa (eye worm) hypothetical protein 0.0072 0.0154 0.0154
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0311 0.0821 0.0819
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0027 0.0071
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0088 0.0316
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0148 0.0367 0.1022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0158 0.0158
Echinococcus granulosus calpain 5 0.1054 0.2897 0.2897
Mycobacterium tuberculosis Conserved hypothetical protein 0.0213 0.0547 0.1291
Plasmodium falciparum histone deacetylase, putative 0.0098 0.0227 0.0824
Giardia lamblia Encystation-specific protease 0.0268 0.07 0.1954
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0268 0.07 0.1954
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Leishmania major histone deacetylase, putative 0.0087 0.0197 0.0406
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0208 0.0535 0.0534
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Loa Loa (eye worm) hypothetical protein 0.0268 0.07 0.07
Entamoeba histolytica protein kinase, putative 0.0744 0.203 0.7426
Onchocerca volvulus 0.0037 0.0055 0.0113
Entamoeba histolytica hypothetical protein 0.0042 0.0071 0.0253
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2975 0.8263 0.8263
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Brugia malayi Trypsin-like protease protein 5 0.0145 0.0359 0.0359
Brugia malayi PXA domain containing protein 0.0042 0.0071 0.0071
Toxoplasma gondii centrin, putative 0.0166 0.0417 0.0864
Schistosoma mansoni histone deacetylase hda2 0.0042 0.007 0.007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3597 1 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0013 0.0039
Brugia malayi hypothetical protein 0.0042 0.0071 0.0071
Entamoeba histolytica glycogen phosphorylase, putative 0.0112 0.0266 0.0967
Loa Loa (eye worm) hypothetical protein 0.07 0.1909 0.1909
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0055 0.0055
Leishmania major centrin, putative 0.0166 0.0417 0.0864
Trypanosoma cruzi caltractin, putative 0.0166 0.0417 0.0415
Loa Loa (eye worm) hypothetical protein 0.0208 0.0535 0.0535
Toxoplasma gondii cathepsin CPL 0.0995 0.2733 0.5684
Brugia malayi hypothetical protein 0.0222 0.0573 0.0573
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0245 0.0638 0.0638
Trypanosoma brucei cysteine peptidase C (CPC) 0.1297 0.3577 0.744
Giardia lamblia Cathepsin L precursor 0.0268 0.07 0.1954
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Toxoplasma gondii cathepsin B 0.1297 0.3577 0.744
Brugia malayi Papain family cysteine protease containing protein 0.0563 0.1524 0.1524
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0064 0.0128
Trichomonas vaginalis calcineurin B subunit, putative 0.0169 0.0425 0.1183
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0002 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0064 0.0064
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0015 0.0015
Trichomonas vaginalis set domain proteins, putative 0.0764 0.2086 0.583
Trichomonas vaginalis calpain, putative 0.0311 0.0821 0.2291
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0268 0.07 0.1954
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0015 0.0014
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0073 0.0073
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0015 0.0015
Plasmodium vivax aspartyl protease, putative 0.0042 0.007 0.0236
Echinococcus granulosus gamma secretase subunit aph 1 0.0254 0.0662 0.0662
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Brugia malayi Serine carboxypeptidase S28 family protein 0.0021 0.0013 0.0013
Onchocerca volvulus Peroxidasin homolog 0.0169 0.0426 0.0878
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0995 0.2733 0.2733
Schistosoma mansoni histone deacetylase hda2 0.0104 0.0244 0.0243
Loa Loa (eye worm) hypothetical protein 0.0087 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0055
Toxoplasma gondii EF hand domain-containing protein 0.0166 0.0417 0.0864
Plasmodium vivax GPI-anchor transamidase, putative 0.0034 0.0049 0.0162
Brugia malayi Eukaryotic aspartyl protease family protein 0.0042 0.007 0.007
Trypanosoma brucei I/6 autoantigen 0.0166 0.0417 0.0864
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0049 0.0131
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0064 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0071 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Brugia malayi calpain family protein 1 0.2809 0.7799 0.7799
Entamoeba histolytica calpain large subunit domain III containing protein 0.0743 0.2029 0.7423
Schistosoma mansoni Mername-AA248 (C02 family) 0.1054 0.2897 0.2897
Loa Loa (eye worm) hypothetical protein 0.0034 0.0049 0.0049
Trypanosoma cruzi calmodulin, putative 0.0166 0.0417 0.0415
Onchocerca volvulus 0.003 0.0037 0.0075
Giardia lamblia Cathepsin B precursor 0.1297 0.3577 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0311 0.0821 0.0819
Echinococcus granulosus cpg binding protein 0.0034 0.0046 0.0046
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0064 0.0062
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0399 0.1067 0.1067
Echinococcus granulosus Transglutaminase 0.0213 0.0547 0.0547
Echinococcus granulosus nervana 2 0.0025 0.0022 0.0022
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0042 0.007 0.007
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0073 0.0148
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0015 0.0015
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0245 0.068
Onchocerca volvulus 0.0764 0.2087 0.4299
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0018 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0073 0.0199
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.0203 0.0201
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0055 0.0105 0.0105
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0018 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0037 0.0055 0.011
Trypanosoma brucei caltractin, putative 0.017 0.0428 0.0886
Entamoeba histolytica prolyl oligopeptidase family protein 0.0208 0.0535 0.1951
Brugia malayi Proteasome A-type and B-type family protein 0.009 0.0203 0.0203
Giardia lamblia Cathepsin B precursor 0.0268 0.07 0.1954
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0037 0.0037
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0097 0.0224 0.0224
Trichomonas vaginalis calmodulin, putative 0.0166 0.0417 0.1161
Schistosoma mansoni histone deacetylase 0.0087 0.0197 0.0196
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0105 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0042 0.007 0.007
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0227 0.0225
Echinococcus granulosus apoptotic protease activating factor 1 0.0222 0.0573 0.0573
Trypanosoma cruzi calmodulin, putative 0.0166 0.0417 0.0415
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Schistosoma mansoni hypothetical protein 0.0025 0.0024 0.0023
Trichomonas vaginalis myosin light chain 1, putative 0.0166 0.0417 0.1161
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0015 0.0015
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0358
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0055 0.0054
Brugia malayi Papain family cysteine protease containing protein 0.0268 0.07 0.07
Echinococcus granulosus histone deacetylase 0.0098 0.0227 0.0227
Plasmodium falciparum calpain 0.0311 0.0821 0.3
Leishmania major proteasome beta 5 subunit, putative 0.009 0.0203 0.0419
Giardia lamblia Cathepsin B precursor 0.1297 0.3577 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0015 0.0014
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0019 0.0047
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.003 0.0029
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0064 0.0064
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.007 0.0147 0.0145
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0073 0.0261
Echinococcus granulosus histone deacetylase 8 0.0042 0.007 0.007
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0037 0.0037
Plasmodium falciparum serine repeat antigen 2 0.0268 0.07 0.2557
Trichomonas vaginalis calcium binding protein, putative 0.0166 0.0417 0.1161
Giardia lamblia Transglutaminase/protease, putative 0.0213 0.0547 0.1525
Schistosoma mansoni survival motor neuron protein 0.0053 0.01 0.0099
Onchocerca volvulus 0.0995 0.2733 0.5629
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0097 0.0224 0.0224
Trypanosoma cruzi cysteine peptidase, putative 0.0295 0.0777 0.0775
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0021 0.0013 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0082 0.008
Brugia malayi Pepsin A precursor 0.0042 0.007 0.007
Plasmodium vivax vivapain-2 0.0995 0.2733 0.9431
Brugia malayi proteasome subunit beta type 3 0.0018 0.0002 0.0002
Schistosoma mansoni centrin-related 0.0166 0.0417 0.0416
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1529 0.4224 1
Plasmodium falciparum serine repeat antigen 9 0.0268 0.07 0.2557
Echinococcus multilocularis cathepsin L cysteine protease 0.0995 0.2733 0.2733
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0166 0.0417 0.0417
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0018 0.0002 0.0001
Loa Loa (eye worm) proteasome subunit beta type 1 0.007 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0268 0.07 0.1954
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0015 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0072 0.0071
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0105 0.0245 0.0506
Loa Loa (eye worm) DEAH box polypeptide 35 0.0064 0.013 0.013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1054 0.2897 0.2896
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Trypanosoma cruzi cysteine peptidase, putative 0.1099 0.3023 0.3022
Schistosoma mansoni hypothetical protein 0.0222 0.0573 0.0572
Toxoplasma gondii troponin c, isotype gamma, putative 0.0166 0.0417 0.0864
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0097 0.0224 0.0224
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0037 0.0072
Mycobacterium tuberculosis Long conserved protein 0.0213 0.0547 0.1291
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Echinococcus multilocularis caspase 0.0245 0.0638 0.0638
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0268 0.07 0.07
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0197 0.0545
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Toxoplasma gondii microneme protein MIC4 0.003 0.0037 0.0072
Schistosoma mansoni cathepsin s 0.0295 0.0777 0.0776
Trypanosoma cruzi centrin, putative 0.017 0.0428 0.0426
Echinococcus multilocularis cysteine protease 0.0995 0.2733 0.2733
Schistosoma mansoni glycogen phosphorylase 0.0048 0.0088 0.0087
Trypanosoma brucei Metacaspase-4 0.0105 0.0245 0.0506
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0105 0.0245 0.0506
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0015 0.0015
Brugia malayi GPI-anchor transamidase 0.0034 0.0049 0.0049
Schistosoma mansoni neprilysin 0.0025 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0095 0.0217 0.0217
Brugia malayi calpain 7 0.1054 0.2897 0.2897
Plasmodium falciparum histone deacetylase 2 0.0098 0.0227 0.0824
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0002 0.0002
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0018 0.0002 0.0002
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0187 0.0474 0.0474
Schistosoma mansoni hypothetical protein 0.0169 0.0426 0.0425
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Leishmania major histone deacetylase, putative 0.0098 0.0227 0.0468
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0015 0.0015
Echinococcus multilocularis GPI anchor transamidase 0.0034 0.0049 0.0049
Entamoeba histolytica calcium-binding protein, putative 0.0166 0.0417 0.152
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0042 0.007 0.0142
Plasmodium falciparum serine repeat antigen 5 0.0268 0.07 0.2557
Schistosoma mansoni calpain C (C02 family) 0.1054 0.2897 0.2897
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1738 0.4806 1
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0166 0.0418 0.0416
Brugia malayi Histone deacetylase 1 0.0087 0.0197 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Brugia malayi Cytochrome P450 family protein 0.0058 0.0114 0.0114
Trypanosoma brucei proteasome subunit beta type-5, putative 0.009 0.0203 0.0419
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0148 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0268 0.07 0.07
Trichomonas vaginalis AGC family protein kinase 0.004 0.0065 0.0176
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0034 0.0049 0.0098
Echinococcus granulosus programmed cell death protein 0.017 0.0428 0.0428
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0311 0.0821 0.1705
Trichomonas vaginalis AGC family protein kinase 0.004 0.0065 0.0176
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0019 0.0019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1054 0.2897 0.2896
Loa Loa (eye worm) blistered cuticle protein 3 0.0169 0.0426 0.0426
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0071 0.0071
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Loa Loa (eye worm) hypothetical protein 0.0268 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0097 0.0224 0.0224
Schistosoma mansoni cathepsin C 0.0268 0.07 0.07
Trichomonas vaginalis AGC family protein kinase 0.004 0.0065 0.0176
Giardia lamblia Hypothetical protein 0.0169 0.0425 0.1183
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Echinococcus multilocularis peroxidasin 0.0169 0.0426 0.0426
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0073 0.0199
Echinococcus multilocularis cathepsin L cysteine protease 0.0995 0.2733 0.2733
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Toxoplasma gondii peptidase c13 family protein 0.0034 0.0049 0.0098
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0018 0.0002 0.0002
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0268 0.07 0.1954
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3597 1 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0311 0.0821 0.2291
Mycobacterium ulcerans hypothetical protein 0.0213 0.0547 0.2825
Trypanosoma brucei metacaspase 5, putative 0.0105 0.0245 0.0506
Toxoplasma gondii hypothetical protein 0.0311 0.0821 0.1705
Brugia malayi Cathepsin L-like precursor 0.0995 0.2733 0.2733
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0043 0.0072 0.0072
Onchocerca volvulus 0.0145 0.0359 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0245 0.068
Entamoeba histolytica cysteine proteinase, putative 0.0995 0.2733 1
Leishmania major programmed cell death 6 protein-like protein 0.0166 0.0417 0.0864
Trypanosoma cruzi cysteine peptidase, putative 0.0563 0.1524 0.1523
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0852 0.2332 0.2332
Mycobacterium ulcerans lipase LipD 0.0037 0.0055 0.0275
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Echinococcus multilocularis calmodulin 0.0166 0.0417 0.0417
Trypanosoma cruzi kinesin, putative 0.0743 0.2029 0.2027
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Brugia malayi cathepsin F-like cysteine proteinase 0.0268 0.07 0.07
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0208 0.0535 0.0534
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0268 0.07 0.07
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0097 0.0223 0.0223
Echinococcus multilocularis proteasome subunit beta type 6 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0187 0.0474 0.0978
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0071 0.0071
Brugia malayi nuclear receptor NHR-88 0.0022 0.0015 0.0015
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0042 0.007 0.0142
Giardia lamblia Cathepsin B precursor 0.0268 0.07 0.1954
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0268 0.07 0.1954
Echinococcus granulosus Dipeptidyl peptidase 9 0.0303 0.0799 0.0799
Schistosoma mansoni hemoglobinase (C13 family) 0.0148 0.0367 0.0367
Giardia lamblia Proteasome subunit beta type 5 precursor 0.009 0.0203 0.0563
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0358
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0114 0.0114
Loa Loa (eye worm) calmodulin-like protein 0.0166 0.0417 0.0417
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0105 0.0245 0.0244
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0071
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0071 0.0071
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.007 0.007
Giardia lamblia Thymus-specific serine protease precursor 0.0021 0.0013 0.003
Trichomonas vaginalis hypothetical protein 0.0311 0.0821 0.2291
Mycobacterium tuberculosis Probable peptidase 0.0709 0.1932 0.4571
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0015 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0197 0.0545
Loa Loa (eye worm) hypothetical protein 0.0268 0.07 0.07
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0071 0.007
Leishmania major histone deacetylase, putative 0.0087 0.0197 0.0406
Trichomonas vaginalis peptide N-glycanase, putative 0.0213 0.0547 0.1525
Brugia malayi proteasome subunit alpha type 1 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0145 0.0359 0.0739
Trypanosoma cruzi prolyl endopeptidase 0.1738 0.4806 0.4805
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.003
Loa Loa (eye worm) hypothetical protein 0.0074 0.0158 0.0158
Echinococcus multilocularis cathepsin b 0.3597 1 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0268 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0995 0.2733 0.2733
Plasmodium vivax proteasome subunit beta type-5, putative 0.009 0.0203 0.0695
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.007 0.0236
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0071 0.0071
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0055 0.0126
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0064 0.0128
Trypanosoma cruzi calmodulin, putative 0.0166 0.0417 0.0415
Loa Loa (eye worm) cathepsin B 0.1297 0.3577 0.3577
Brugia malayi calpain 5 0.0311 0.0821 0.0821
Loa Loa (eye worm) hypothetical protein 0.1738 0.4806 0.4806
Brugia malayi proteasome subunit alpha type 2 0.0018 0.0002 0.0002
Trypanosoma cruzi metacaspase, putative 0.0105 0.0245 0.0243
Trypanosoma cruzi Protein kinase B 0.0028 0.003 0.0028
Echinococcus granulosus flap endonuclease 1 0.0027 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0025 0.0024 0.0023
Onchocerca volvulus 0.0268 0.07 0.1443
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0311 0.0821 0.2291
Echinococcus granulosus calpain A 0.2978 0.827 0.827
Trypanosoma brucei calmodulin, putative 0.0166 0.0417 0.0864
Brugia malayi cathepsin L precursor 0.0268 0.07 0.07
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Echinococcus granulosus calumenin 0.0169 0.0425 0.0425
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0071 0.007
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.009 0.0203 0.0201
Mycobacterium leprae Conserved hypothetical protein 0.0213 0.0547 0.2825
Echinococcus multilocularis calcium uptake protein 1 0.0169 0.0425 0.0425
Mycobacterium ulcerans beta-lactamase 0.0037 0.0055 0.0275
Trypanosoma brucei histone deacetylase 3 0.0098 0.0227 0.0468
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0015 0.0015
Loa Loa (eye worm) aspartyl protease 6 0.0042 0.007 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0015 0.0015
Echinococcus granulosus Glycosyl transferase family 35 0.0112 0.0266 0.0266
Plasmodium vivax plasmepsin IV, putative 0.0042 0.007 0.0236
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0071 0.007
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0015 0.0014
Brugia malayi Animal haem peroxidase family protein 0.0169 0.0426 0.0426
Onchocerca volvulus 0.0995 0.2733 0.5629
Leishmania major histone deacetylase, putative 0.0098 0.0227 0.0468
Onchocerca volvulus Peroxidasin homolog 0.0169 0.0426 0.0878
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0071 0.007
Schistosoma mansoni cathepsin F (C01 family) 0.0995 0.2733 0.2732
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0671 0.1827 0.1827
Giardia lamblia Glycogen phosphorylase 0.0112 0.0266 0.0739
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0027 0.0025
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0303 0.0799 0.0798
Plasmodium vivax aspartyl protease, putative 0.0204 0.0522 0.1796
Echinococcus multilocularis proteasome subunit beta type 7 0.0018 0.0002 0.0002
Toxoplasma gondii calmodulin CAM1 0.0169 0.0425 0.088
Echinococcus granulosus caspase 3 0.0141 0.0346 0.0346
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0345 0.0345
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Schistosoma mansoni neuronal calcium sensor 0.0166 0.0417 0.0416
Schistosoma mansoni histone deacetylase 0.0087 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0166 0.0417 0.0417
Trypanosoma cruzi oligopeptidase b 0.0709 0.1932 0.193
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0019 0.0047
Brugia malayi Cell death protein 3 precursor 0.0327 0.0865 0.0865
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0018 0.0002 0.0001
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0019 0.0018
Leishmania major kinesin, putative 0.0743 0.2029 0.4219
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Brugia malayi Protein kinase domain containing protein 0.004 0.0065 0.0065
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0804 0.2199 0.2198
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0709 0.1932 1
Toxoplasma gondii hypothetical protein 0.0208 0.0535 0.1109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0563 0.1524 0.4259
Loa Loa (eye worm) hypothetical protein 0.0097 0.0224 0.0224
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0145 0.0359 0.0358
Schistosoma mansoni neuronal calcium sensor 0.0166 0.0417 0.0416
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0166 0.0417 0.0864
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Brugia malayi EF hand family protein 0.0169 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0071
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0055 0.0126
Mycobacterium ulcerans putative transglutaminase-like protein 0.0213 0.0547 0.2825
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0015 0.0015
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0042 0.007 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0268 0.07 0.1954
Plasmodium vivax calpain, putative 0.1054 0.2897 1
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0359
Onchocerca volvulus 0.0995 0.2733 0.5629
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0027 0.0053
Onchocerca volvulus 0.0022 0.0015 0.0031
Plasmodium vivax SET domain protein, putative 0.0097 0.0223 0.0764
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0245 0.068
Onchocerca volvulus 0.0166 0.0417 0.0859
Trypanosoma brucei mitochondrial calcium uptake 1 0.0166 0.0417 0.0864
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Onchocerca volvulus Notchless protein homolog 0.0018 0.0002 0.0004
Trypanosoma brucei prolyl endopeptidase 0.1738 0.4806 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0344
Schistosoma mansoni cathepsin B (C01 family) 0.0268 0.07 0.07
Echinococcus multilocularis cathepsin b 0.3597 1 1
Toxoplasma gondii PAN domain-containing protein 0.003 0.0037 0.0072
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0071 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.07 0.1954
Brugia malayi cathepsin L-like precursor 0.07 0.1909 0.1909
Leishmania major protein kinase, putative 0.0166 0.0418 0.0866
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0254 0.0662 0.0662
Schistosoma mansoni hypothetical protein 0.0025 0.0024 0.0023
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0071 0.007
Echinococcus granulosus Proteasome subunit alpha type 7 0.0018 0.0002 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0995 0.2733 0.2733
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0311 0.0821 0.1705
Echinococcus granulosus prolyl endopeptidase 0.1738 0.4806 0.4806
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0245 0.068
Loa Loa (eye worm) histone deacetylase 7A 0.0098 0.0227 0.0227
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0019 0.0039
Loa Loa (eye worm) hypothetical protein 0.0145 0.0359 0.0359
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0268 0.07 0.2412
Entamoeba histolytica prolyl oligopeptidase family protein 0.0208 0.0535 0.1951
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.013 0.0267
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.2896
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0055
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0073 0.0148
Echinococcus multilocularis transmembrane protease serine 3 0.0145 0.0359 0.0359
Onchocerca volvulus 0.0048 0.0087 0.018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0344
Schistosoma mansoni calmodulin related calcium binding protein 0.0166 0.0417 0.0416
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0268 0.07 0.07
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0015 0.0015
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0166 0.0417 0.0415
Brugia malayi proteasome subunit alpha type 4 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0015 0.0014
Brugia malayi Animal haem peroxidase family protein 0.0169 0.0426 0.0426
Onchocerca volvulus Peroxidase homolog 0.0169 0.0426 0.0878
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Brugia malayi Peroxidasin 0.0169 0.0426 0.0426
Toxoplasma gondii kringle domain-containing protein 0.0046 0.0082 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Loa Loa (eye worm) programmed cell death protein 6 0.0169 0.0425 0.0425
Onchocerca volvulus 0.0021 0.0013 0.0026
Onchocerca volvulus Peroxidase homolog 0.0169 0.0426 0.0878
Schistosoma mansoni calmodulin 0.0166 0.0417 0.0416
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0268 0.07 0.07
Echinococcus multilocularis histone deacetylase 7 0.0098 0.0227 0.0227
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0019 0.0047
Toxoplasma gondii microneme protein, putative 0.003 0.0037 0.0072
Loa Loa (eye worm) hypothetical protein 0.0268 0.07 0.07
Trypanosoma brucei calpain-like protein, putative 0.1054 0.2897 0.6027
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0325 0.0325
Brugia malayi Cathepsin L-like precursor 0.07 0.1909 0.1909
Echinococcus multilocularis calpain A 0.2978 0.827 0.827
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1738 0.4806 0.4806
Echinococcus granulosus histone deacetylase 6 0.0098 0.0227 0.0227
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Trypanosoma cruzi centrin, putative 0.017 0.0428 0.0426
Onchocerca volvulus 0.0169 0.0426 0.0878
Leishmania major calmodulin-like protein 0.0166 0.0417 0.0864
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0097 0.0223 0.0223
Brugia malayi Histone deacetylase family protein 0.0098 0.0227 0.0227
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0995 0.2733 0.2733
Plasmodium falciparum plasmepsin IX 0.0204 0.0522 0.1904
Toxoplasma gondii exonuclease III APE 0.004 0.0064 0.0128
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0105 0.0105
Brugia malayi Animal haem peroxidase family protein 0.0169 0.0426 0.0426
Schistosoma mansoni peroxidasin 0.0169 0.0426 0.0425
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0055 0.0183
Brugia malayi Animal haem peroxidase family protein 0.0169 0.0426 0.0426
Toxoplasma gondii histone deacetylase HDAC1 0.0098 0.0227 0.0468
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0145 0.0359 0.0359
Toxoplasma gondii preprocathepsin c precursor, putative 0.0268 0.07 0.1454
Trypanosoma brucei histone deacetylase 1 0.0087 0.0197 0.0406
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus granulosus enteropeptidase 0.0145 0.0359 0.0359
Echinococcus multilocularis Glutaredoxin protein 5 0.0025 0.0022 0.0022
Echinococcus granulosus calmodulin 0.0166 0.0417 0.0417
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0071 0.007
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0268 0.07 0.2412
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Plasmodium vivax unspecified product 0.0295 0.0777 0.2676
Echinococcus granulosus nervana 2 0.0025 0.0022 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0055 0.0053
Echinococcus multilocularis beta adrenergic receptor kinase 0.0043 0.0072 0.0072
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0073 0.0261
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0227 0.0225
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0325 0.0673
Toxoplasma gondii subtilisin SUB12 0.003 0.0037 0.0072
Echinococcus granulosus EF HAND 1 calcium binding site 0.0166 0.0417 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.6027
Brugia malayi prolyl oligopeptidase family protein 0.0208 0.0535 0.0535
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0166 0.0418 0.1436
Echinococcus granulosus subfamily T1A non peptidase ue 0.0018 0.0002 0.0002
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0166 0.0417 0.0416
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0034 0.0049 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.007 0.0147 0.0147
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0071 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0345 0.0345
Toxoplasma gondii aspartyl protease 0.0042 0.007 0.0142
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0002 0.0002
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0208 0.0535 0.1951
Echinococcus granulosus cathepsin l1 0.0995 0.2733 0.2733
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0019 0.004
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0025 0.0022 0.0022
Brugia malayi histone deacetylase 1 (HD1) 0.0087 0.0197 0.0197
Plasmodium falciparum peptidase, putative 0.0208 0.0535 0.1951
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0345 0.0345
Trichomonas vaginalis AGC family protein kinase 0.004 0.0065 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.009 0.0203 0.0476
Trypanosoma cruzi kinesin, putative 0.0743 0.2029 0.2027
Toxoplasma gondii PAN domain-containing protein 0.003 0.0037 0.0072
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0145 0.0359 0.0359
Loa Loa (eye worm) peptidase C13 family protein 0.0148 0.0367 0.0367
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.003 0.0101
Entamoeba histolytica glycogenphosphorylase, putative 0.0048 0.0088 0.0316
Schistosoma mansoni reticulocalbin 0.0169 0.0425 0.0424
Trypanosoma brucei metacaspase 0.0105 0.0245 0.0506
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0071 0.0071
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3597 1 1
Echinococcus granulosus calbindin 32 0.0169 0.0425 0.0425
Brugia malayi Papain family cysteine protease containing protein 0.0268 0.07 0.07
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0303 0.0799 0.0797
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0197 0.0545
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0019 0.0062
Brugia malayi hypothetical protein 0.0258 0.0674 0.0674
Plasmodium falciparum cysteine proteinase falcipain 1 0.0563 0.1524 0.5575
Toxoplasma gondii peptidase family M13 protein 0.0097 0.0224 0.0463
Trichomonas vaginalis calcium binding protein, putative 0.017 0.0428 0.1191
Echinococcus granulosus histone deacetylase 6 0.0104 0.0244 0.0244
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0019 0.0035
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0105 0.0245 0.0506
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0227 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0071 0.0193
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0227 0.0226
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0148 0.0367 0.1022
Echinococcus granulosus survival motor neuron protein 1 0.0258 0.0674 0.0674
Entamoeba histolytica cysteine proteinase, putative 0.0995 0.2733 1
Brugia malayi beta-lactamase family protein 0.0037 0.0055 0.0055
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0064 0.0319
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0709 0.1932 0.4017
Loa Loa (eye worm) hypothetical protein 0.0295 0.0777 0.0777
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0019 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0072 0.0071
Plasmodium vivax aspartyl proteinase, putative 0.0042 0.007 0.0236
Leishmania major hypothetical protein, unknown function 0.0311 0.0821 0.1705
Onchocerca volvulus 0.0055 0.0105 0.0217
Loa Loa (eye worm) calpain 0.1054 0.2897 0.2897
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0015 0.0015
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0071 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Mycobacterium tuberculosis Conserved protein 0.0037 0.0055 0.0126
Echinococcus granulosus centrin 2 0.0166 0.0417 0.0417
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Schistosoma mansoni hypothetical protein 0.0169 0.0426 0.0425
Echinococcus multilocularis tissue type plasminogen activator 0.0046 0.0082 0.0082
Leishmania major phospholipase c-like protein 0.0166 0.0417 0.0864
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0043 0.0072 0.0072
Leishmania major oligopeptidase b 0.0709 0.1932 0.4017
Loa Loa (eye worm) hypothetical protein 0.0167 0.0419 0.0419
Loa Loa (eye worm) hypothetical protein 0.0145 0.0359 0.0359
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0051 0.0051
Echinococcus granulosus cathepsin L cysteine proteinase 0.0995 0.2733 0.2733
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0055 0.0126
Brugia malayi Papain family cysteine protease containing protein 0.0563 0.1524 0.1524
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0268 0.07 0.1954
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.6027
Mycobacterium ulcerans hypothetical protein 0.0037 0.0055 0.0275
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0325 0.1676
Brugia malayi calpain 5 0.0743 0.2029 0.2029
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0166 0.0417 0.0417
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0002 0.0002
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0169 0.0425 0.0423
Toxoplasma gondii centrin 0.0166 0.0417 0.0864
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0547 0.1481 0.1481
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0055 0.0148
Echinococcus granulosus Glutaredoxin protein 5 0.0025 0.0022 0.0022
Giardia lamblia Cathepsin B precursor 0.1297 0.3577 1
Entamoeba histolytica hypothetical protein 0.0042 0.0071 0.0253
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0145 0.0359 0.0359
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0234 0.0606 0.143
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0024 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0295 0.0777 0.0777
Onchocerca volvulus 0.0042 0.007 0.0145
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0018 0.0002 0.0002
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0474 0.0474
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0051 0.0101
Onchocerca volvulus 0.003 0.0037 0.0075
Loa Loa (eye worm) cysteine protease 0.0995 0.2733 0.2733
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0019 0.0018
Schistosoma mansoni reticulocalbin 0.0166 0.0417 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0071 0.0193
Schistosoma mansoni cpg binding protein 0.0032 0.0041 0.0041
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0049 0.009 0.0089
Echinococcus granulosus calpain A 0.1054 0.2897 0.2897
Giardia lamblia Hypothetical protein 0.0268 0.07 0.1954
Brugia malayi proteasome subunit beta type 2 0.0043 0.0073 0.0073
Trypanosoma cruzi cysteine peptidase, putative 0.1099 0.3023 0.3022
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0015 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0055 0.0148
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0071 0.0071
Trypanosoma brucei cysteine peptidase, putative 0.0311 0.0821 0.1705
Trypanosoma brucei calmodulin, putative 0.0169 0.0425 0.088
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0027 0.0053
Brugia malayi proteasome subunit beta type 1 0.007 0.0147 0.0147
Leishmania major cathepsin L-like protease 0.0995 0.2733 0.5684
Onchocerca volvulus 0.0995 0.2733 0.5629
Brugia malayi Histone deacetylase family protein 0.0098 0.0227 0.0227
Trypanosoma cruzi cysteine protease, putative 0.0563 0.1524 0.1523
Loa Loa (eye worm) hypothetical protein 0.0327 0.0865 0.0865
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0073 0.0073
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0399 0.1067 0.1066
Schistosoma mansoni hypothetical protein 0.0311 0.0821 0.082
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0311 0.0821 0.2291
Trypanosoma brucei metacaspase MCA2 0.0105 0.0245 0.0506
Loa Loa (eye worm) animal heme peroxidase 0.0169 0.0426 0.0426
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0325 0.0325
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.007 0.0145
Schistosoma mansoni caspase-3 (C14 family) 0.0245 0.0638 0.0637
Onchocerca volvulus 0.003 0.0037 0.0075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0345 0.0345
Trypanosoma cruzi I/6 autoantigen, putative 0.0166 0.0417 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0166 0.0417 0.1161
Schistosoma mansoni cercarial elastase (S01 family) 0.0145 0.0359 0.0358
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0303 0.0799 0.1658
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0037 0.0037
Mycobacterium leprae Probable lipase LipE 0.0037 0.0055 0.0275
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0208 0.0535 0.1109
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0268 0.07 0.2412
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0025 0.0023 0.0072
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.2896
Echinococcus granulosus GPI anchor transamidase 0.0034 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0148 0.0367 0.1022
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0268 0.07 0.2412
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3597 1 1
Leishmania major cathepsin L-like protease 0.1099 0.3023 0.6288
Loa Loa (eye worm) hypothetical protein 0.07 0.1909 0.1909
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0358
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0042 0.007 0.007
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0064 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Trichomonas vaginalis calmodulin, putative 0.0166 0.0417 0.1161
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0071 0.0193
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1297 0.3577 0.3576
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0019 0.0018
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0015 0.0014
Trichomonas vaginalis calmodulin, putative 0.0166 0.0417 0.1161
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0197 0.0195
Echinococcus granulosus cathepsin L 0.0268 0.07 0.07
Echinococcus multilocularis calpain family protein 1, d 0.2066 0.5722 0.5722
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0145 0.0359 0.0359
Echinococcus multilocularis neurocalcin 0.0166 0.0417 0.0417
Toxoplasma gondii calcium-dependent protein kinase 0.0169 0.0425 0.0882
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0018 0.0002 0.0001
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0268 0.07 0.07
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1297 0.3577 0.744
Echinococcus granulosus cathepsin b 0.3597 1 1
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0018 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0074 0.0158 0.0158
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0166 0.0417 0.0415
Echinococcus multilocularis calpain 0.1054 0.2897 0.2897
Plasmodium vivax plasmepsin V, putative 0.0042 0.007 0.0236
Echinococcus multilocularis histone deacetylase 3 0.0087 0.0197 0.0197
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0049 0.0131
Echinococcus granulosus calpain 0.1054 0.2897 0.2897
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0303 0.0799 0.1658
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0268 0.07 0.1954
Brugia malayi Trypsin family protein 0.0145 0.0359 0.0359
Echinococcus multilocularis Mastin 0.0145 0.0359 0.0359
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0268 0.07 0.2412
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0311 0.0821 0.1705
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.003
Echinococcus multilocularis programmed cell death protein 0.017 0.0428 0.0428
Trypanosoma brucei Calpain-like protein 2 0.0311 0.0821 0.1705
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.2498 0.693 0.693
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0197 0.0545
Schistosoma mansoni gamma-secretase subunit aph-1 0.0254 0.0662 0.0661
Plasmodium vivax vivapain-1 0.0563 0.1524 0.5258
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.009 0.0089
Trichomonas vaginalis calmodulin-2, putative 0.0166 0.0417 0.1161
Trichomonas vaginalis glycogen phosphorylase, putative 0.0112 0.0266 0.0739
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1099 0.3023 0.6288
Mycobacterium tuberculosis Conserved protein 0.0037 0.0055 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0071 0.0071
Giardia lamblia Alanyl dipeptidyl peptidase 0.0208 0.0535 0.149
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0208 0.0535 0.1951
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0019 0.0017
Echinococcus granulosus geminin 0.0169 0.0426 0.0426
Schistosoma mansoni calmodulin 0.0166 0.0417 0.0416
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Loa Loa (eye worm) hypothetical protein 0.0187 0.0474 0.0474
Trypanosoma cruzi metacaspase, putative 0.0105 0.0245 0.0243
Mycobacterium tuberculosis Conserved hypothetical protein 0.0213 0.0547 0.1291
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0015 0.0015
Onchocerca volvulus Cell death protein 3 homolog 0.0327 0.0865 0.1782
Trypanosoma brucei Calpain-like protein 1.1 0.0311 0.0821 0.1705
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Leishmania major hypothetical protein, conserved 0.0046 0.0082 0.0167
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0064 0.0064
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0002 0.0002
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0071 0.0071
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0563 0.1524 0.1524
Brugia malayi Trypsin family protein 0.0145 0.0359 0.0359
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0166 0.0417 0.0417
Trichomonas vaginalis calcineurin B subunit, putative 0.0166 0.0417 0.1161
Brugia malayi programmed cell death protein 6 0.0166 0.0417 0.0417
Trypanosoma brucei histone deacetylase 4 0.0098 0.0227 0.0468
Schistosoma mansoni cathepsin D (A01 family) 0.0231 0.0597 0.0597
Entamoeba histolytica calpain family cysteine protease, putative 0.0311 0.0821 0.3
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0268 0.07 0.07
Trichomonas vaginalis calmodulin, putative 0.0166 0.0417 0.1161
Brugia malayi Pre-SET motif family protein 0.0097 0.0223 0.0223
Entamoeba histolytica cysteine proteinase, putative 0.0563 0.1524 0.5575
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0025 0.0023 0.0076
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0197 0.0545
Toxoplasma gondii aspartyl protease ASP1 0.0042 0.007 0.0142
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0995 0.2733 0.2733
Onchocerca volvulus 0.003 0.0037 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0015 0.0015
Giardia lamblia Cysteine protease 0.0268 0.07 0.1954
Loa Loa (eye worm) hypothetical protein 0.0145 0.0359 0.0359
Echinococcus multilocularis glycogen phosphorylase 0.0112 0.0266 0.0266
Echinococcus multilocularis gamma secretase subunit aph 1 0.0254 0.0662 0.0662
Schistosoma mansoni hypothetical protein 0.0053 0.01 0.0099
Toxoplasma gondii cathepsin CPC1 0.0268 0.07 0.1454
Onchocerca volvulus Cathepsin F homolog 0.0995 0.2733 0.5629
Entamoeba histolytica cysteine protease, putative 0.0268 0.07 0.2557
Loa Loa (eye worm) trypsin family protein 0.0145 0.0359 0.0359
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0015 0.0014
Brugia malayi Peptidase C13 family protein 0.0148 0.0367 0.0367
Toxoplasma gondii microneme protein MIC17A 0.003 0.0037 0.0072
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0166 0.0418 0.0416
Plasmodium vivax histone deacetylase 1, putative 0.0087 0.0197 0.0673
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0208 0.0535 0.149
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0064 0.0213
Trypanosoma brucei centrin-3 0.017 0.0428 0.0886
Schistosoma mansoni rab 0.0166 0.0417 0.0416
Plasmodium vivax histone deacetylase 2, putative 0.0098 0.0227 0.0777
Toxoplasma gondii histone deacetylase HDAC2 0.0087 0.0197 0.0406
Echinococcus granulosus glycoprotein Antigen 5 0.0145 0.0359 0.0359
Giardia lamblia GPI-anchor transamidase, putative 0.0034 0.0049 0.0131
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0203 0.0563
Toxoplasma gondii prolyl endopeptidase 0.1738 0.4806 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.07 0.1909 0.5334
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0013 0.003
Brugia malayi Thioredoxin family protein 0.0213 0.0547 0.0547
Schistosoma mansoni hypothetical protein 0.0213 0.0547 0.0546
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Plasmodium falciparum proteasome subunit beta type-1, putative 0.007 0.0147 0.0532
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2975 0.8263 0.8263
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0268 0.07 0.07
Plasmodium falciparum centrin-1 0.0166 0.0417 0.152
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.0819
Loa Loa (eye worm) histone deacetylase 0.0098 0.0227 0.0227
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0013 0.003
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0055 0.0148
Echinococcus granulosus glycogen phosphorylase 0.0112 0.0266 0.0266
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.6027
Onchocerca volvulus Deterin homolog 0.0187 0.0474 0.0978
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0995 0.2733 0.2733
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0148 0.0367 0.1022
Schistosoma mansoni cathepsin D (A01 family) 0.0231 0.0597 0.0597
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Brugia malayi PAN domain containing protein 0.003 0.0037 0.0037
Echinococcus multilocularis histone deacetylase 8 0.0042 0.007 0.007
Entamoeba histolytica cysteine proteinase, putative 0.0563 0.1524 0.5575
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0055
Onchocerca volvulus 0.0145 0.0359 0.0739
Giardia lamblia Cathepsin L precursor 0.0268 0.07 0.1954
Trypanosoma cruzi cysteine peptidase, putative 0.0995 0.2733 0.2731
Echinococcus granulosus serine/threonine protein kinase 0.0028 0.003 0.003
Mycobacterium tuberculosis Conserved protein 0.0037 0.0055 0.0126
Plasmodium falciparum plasmepsin X 0.0204 0.0522 0.1904
Trypanosoma cruzi major cysteine proteinase, putative 0.0268 0.07 0.0698
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0145 0.0359 0.0358
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0015 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0268 0.07 0.1954
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Plasmodium falciparum proteasome subunit beta type-5 0.009 0.0203 0.0737
Echinococcus multilocularis apoptotic protease activating factor 1 0.0222 0.0573 0.0573
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0227 0.0225
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0042 0.007 0.0191
Mycobacterium tuberculosis Hypothetical protein 0.0213 0.0547 0.1291
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0019 0.0019
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0563 0.1524 0.1523
Trichomonas vaginalis conserved hypothetical protein 0.0166 0.0417 0.1161
Loa Loa (eye worm) hypothetical protein 0.0295 0.0777 0.0777
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0311 0.0821 0.1705
Loa Loa (eye worm) peptidase family M13 containing protein 0.0072 0.0154 0.0154
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0015 0.0014
Brugia malayi aspartic protease BmAsp-2, identical 0.0042 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0311 0.0821 0.0821
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0018 0.0002 0.0001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0311 0.0821 0.0819
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Trypanosoma brucei histone deacetylase, putative 0.0098 0.0227 0.0468
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Plasmodium falciparum metacaspase-like protein 0.0105 0.0245 0.089
Brugia malayi EF hand family protein 0.0166 0.0417 0.0417
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0019 0.0018
Echinococcus multilocularis dnaJ subfamily B 0.0451 0.1214 0.1214
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0197 0.0545
Trypanosoma cruzi cruzipain precursor, putative 0.0295 0.0777 0.0775
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0311 0.0821 0.2291
Plasmodium falciparum metacaspase 1 0.0105 0.0245 0.089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0995 0.2733 0.7639
Leishmania major calpain family cysteine protease-like protein 0.0311 0.0821 0.1705
Schistosoma mansoni endothelin-converting enzyme-related 0.0024 0.0019 0.0018
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0055 0.0055
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0071 0.0071
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0268 0.07 0.2412
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0048 0.0088 0.0204
Entamoeba histolytica cysteine protease, putative 0.0563 0.1524 0.5575
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0071 0.0193
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0019 0.0018
Onchocerca volvulus 0.0995 0.2733 0.5629
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0268 0.07 0.2557
Echinococcus multilocularis cathepsin L 0.0268 0.07 0.07
Onchocerca volvulus 0.0213 0.0547 0.1127
Brugia malayi Animal haem peroxidase family protein 0.0169 0.0426 0.0426
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0303 0.0799 0.1658
Schistosoma mansoni neuronal calcium sensor 0.0166 0.0417 0.0416
Brugia malayi Cathepsin L-like precursor 0.0995 0.2733 0.2733
Echinococcus multilocularis calpain 7 (C02 family) 0.1054 0.2897 0.2897
Trypanosoma cruzi metacaspase, putative 0.0105 0.0245 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Plasmodium falciparum plasmepsin IV 0.0042 0.007 0.025
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.2896
Trichomonas vaginalis centrin, putative 0.0166 0.0417 0.1161
Loa Loa (eye worm) calpain family protein 1 0.2809 0.7799 0.7799
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0166 0.0418 0.0866
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0013 0.0039
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0208 0.0535 0.149
Trichomonas vaginalis centrin, putative 0.0166 0.0417 0.1161
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0046 0.0082 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0995 0.2733 0.7639
Leishmania major cathepsin L-like protease 0.1099 0.3023 0.6288
Echinococcus multilocularis calpain 5 0.1054 0.2897 0.2897
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.003 0.0101
Loa Loa (eye worm) hypothetical protein 0.0169 0.0426 0.0426
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0709 0.1932 0.4571
Mycobacterium ulcerans zinc metalloprotease 0.0097 0.0224 0.1153
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0015 0.0015
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0105 0.0245 0.068
Echinococcus multilocularis calumenin 0.0169 0.0425 0.0425
Toxoplasma gondii histone deacetylase HDAC3 0.0087 0.0197 0.0406
Schistosoma mansoni cpg binding protein 0.0034 0.0046 0.0046
Onchocerca volvulus 0.003 0.0037 0.0075
Plasmodium vivax unspecified product 0.0268 0.07 0.2412
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0166 0.0417 0.1161
Trypanosoma brucei protein I/6 0.0166 0.0417 0.0864
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1054 0.2897 0.2896
Plasmodium falciparum plasmepsin III 0.0042 0.007 0.025
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0071 0.007
Brugia malayi hypothetical protein 0.0169 0.0426 0.0426
Brugia malayi Trypsin family protein 0.0145 0.0359 0.0359
Schistosoma mansoni hypothetical protein 0.0451 0.1214 0.1213
Entamoeba histolytica hypothetical protein, conserved 0.0208 0.0535 0.1951
Echinococcus multilocularis EF hand domain containing family member A2 0.0166 0.0417 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0055 0.0053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0345 0.0345
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0015 0.0015
Leishmania major i/6 autoantigen-like protein 0.0166 0.0417 0.0864
Brugia malayi prolyl oligopeptidase family protein 0.0547 0.1481 0.1481
Echinococcus granulosus Proteasome subunit alpha beta 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0025 0.0024 0.0023
Schistosoma mansoni ap endonuclease 0.004 0.0064 0.0063
Echinococcus multilocularis tumor protein p63 0.0373 0.0995 0.0995
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0055
Entamoeba histolytica cysteine protease, putative 0.0268 0.07 0.2557
Leishmania major centrin, putative 0.0166 0.0417 0.0864
Plasmodium vivax histone deacetylase, putative 0.0042 0.007 0.0237
Entamoeba histolytica protein kinase, putative 0.004 0.0065 0.023
Schistosoma mansoni ap endonuclease 0.004 0.0064 0.0063
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0268 0.07 0.2412
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0071 0.007
Plasmodium falciparum GPI-anchor transamidase, putative 0.0034 0.0049 0.0172

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2100 nM Inhibition of AKT3 in presence of 0.2 uM ATP ChEMBL. 16765046
IC50 (binding) = 2100 nM Inhibition of AKT3 in presence of 0.2 uM ATP ChEMBL. 16765046

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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