Detailed information for compound 372798

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 297.352 | Formula: C17H19N3O2
  • H donors: 1 H acceptors: 4 LogP: 2.56 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)/C=C/c1nn(c(c1)c1ccccn1)C1CCCCC1
  • InChi: 1S/C17H19N3O2/c21-17(22)10-9-13-12-16(15-8-4-5-11-18-15)20(19-13)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H,21,22)/b10-9+
  • InChiKey: SKVOHUFIEYDQGB-MDZDMXLPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0159 0.0745 0.0829
Loa Loa (eye worm) hypothetical protein 0.006 0.0192 0.0192
Brugia malayi Cathepsin L-like precursor 0.0173 0.0824 0.0822
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0625 0.1545
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0374 0.1951 0.1993
Echinococcus multilocularis protein jagged 2 0.0026 0.0004 0.0001
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Loa Loa (eye worm) calpain D 0.0125 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.007 0.0249 0.0249
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Giardia lamblia Glycogen phosphorylase 0.0105 0.0444 0.1392
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.0551 0.0561
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.2179 0.2227
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0035 0.0035
Loa Loa (eye worm) prolyl oligopeptidase 0.0524 0.2791 0.2791
Schistosoma mansoni ap endonuclease 0.0038 0.0072 0.0071
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0141 0.0648 0.2129
Trypanosoma cruzi prolyl endopeptidase 0.1771 0.9775 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.0551 0.1361
Schistosoma mansoni neuronal calcium sensor 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0568 0.3035 0.7525
Brugia malayi prolyl oligopeptidase family protein 0.021 0.1032 0.103
Trypanosoma cruzi calmodulin, putative 0.006 0.0192 0.0194
Loa Loa (eye worm) hypothetical protein 0.0141 0.0648 0.0648
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Brugia malayi gamma-secretase subunit aph-1 0.0244 0.1223 0.122
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0072 0.0205
Echinococcus granulosus calumenin 0.0061 0.0196 0.0198
Loa Loa (eye worm) hypothetical protein 0.007 0.0249 0.0249
Brugia malayi hypothetical protein 0.003 0.0024 0.0021
Echinococcus granulosus peroxidasin 0.0321 0.1655 0.1691
Mycobacterium ulcerans proteasome PrcB 0.0159 0.0745 0.184
Echinococcus multilocularis calmodulin 0.006 0.0192 0.0194
Schistosoma mansoni notch 0.0026 0.0004 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0125 0.0555 0.137
Giardia lamblia Cathepsin B precursor 0.0141 0.0648 0.2039
Giardia lamblia Cathepsin L precursor 0.0141 0.0648 0.2039
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0001
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0151 0.0148
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0655 0.3526 0.3526
Loa Loa (eye worm) hypothetical protein 0.0125 0.0555 0.0555
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.021 0.1032 0.1053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Schistosoma mansoni slit 0.0026 0.0004 0.0001
Entamoeba histolytica calmodulin, putative 0.006 0.0192 0.0601
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0035 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.036 0.0366
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0035 0.008
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0404 0.0411
Brugia malayi proteasome subunit beta type 2 0.0047 0.0119 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0077 0.0076
Echinococcus granulosus inhibitor of apoptosis protein 0.0176 0.084 0.0857
Plasmodium falciparum cysteine proteinase falcipain 3 0.0568 0.3035 1
Echinococcus multilocularis calpain A 0.116 0.6354 0.6499
Giardia lamblia Cathepsin B precursor 0.0591 0.3165 1
Onchocerca volvulus 0.0057 0.0175 0.0176
Echinococcus granulosus programmed cell death protein 0.006 0.0192 0.0194
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0159 0.0745 0.1068
Plasmodium falciparum serine repeat antigen 8 0.0141 0.0648 0.2129
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0115 0.0115
Echinococcus multilocularis neuronal calcium sensor 0.006 0.0192 0.0194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0389 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.0648 0.1602
Loa Loa (eye worm) hypothetical protein 0.0141 0.0648 0.0648
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0298 0.1523 0.1555
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0524 0.2791 0.2853
Leishmania major hypothetical protein, unknown function 0.0125 0.0555 0.0565
Entamoeba histolytica hypothetical protein 0.0039 0.0077 0.0221
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.006 0.0192 0.0194
Toxoplasma gondii EFHC1, putative 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) hypothetical protein 0.0191 0.0927 0.0927
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) hypothetical protein 0.0092 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0975 0.5316 0.5316
Onchocerca volvulus 0.0176 0.084 0.0857
Onchocerca volvulus Cathepsin F homolog 0.0568 0.3035 0.3103
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0035 0.0032
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0072 0.0071
Toxoplasma gondii centrin 0.006 0.0192 0.0194
Giardia lamblia Cathepsin B precursor 0.0591 0.3165 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0077 0.0076
Trichomonas vaginalis calpain, putative 0.0125 0.0555 0.137
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0077 0.0076
Entamoeba histolytica cysteine protease, putative 0.0141 0.0648 0.211
Brugia malayi Pepsin A precursor 0.003 0.0024 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0141 0.0648 0.1602
Brugia malayi Trypsin family protein 0.007 0.0249 0.0247
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0176 0.084 0.0857
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0524 0.2791 0.2853
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0039 0.0077 0.0076
Brugia malayi hypothetical protein 0.0039 0.0077 0.0074
Toxoplasma gondii exonuclease III APE 0.0038 0.0072 0.0071
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Loa Loa (eye worm) hypothetical protein 0.021 0.1032 0.1032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0077
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0314 0.1616 0.1651
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0151 0.0152
Loa Loa (eye worm) trypsin family protein 0.007 0.0249 0.0249
Loa Loa (eye worm) Notch2 0.0026 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0173 0.0824 0.084
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Schistosoma mansoni notch 0.0026 0.0004 0.0001
Mycobacterium tuberculosis Probable peptidase 0.0721 0.3892 0.4504
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0047 0.0119 0.0361
Onchocerca volvulus 0.003 0.0024 0.0022
Toxoplasma gondii troponin c, isotype gamma, putative 0.006 0.0192 0.0194
Entamoeba histolytica calcium binding family protein 0.006 0.0192 0.0601
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0127 0.0567 0.0621
Loa Loa (eye worm) hypothetical protein 0.0053 0.0151 0.0151
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0141 0.0648 0.2129
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0072 0.0262 0.0833
Echinococcus multilocularis neurocalcin 0.006 0.0192 0.0194
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0389 0.0395
Brugia malayi Trypsin family protein 0.007 0.0249 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0648 0.1602
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.2179 0.2227
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0721 0.3892 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0072 0.0228
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0151 0.0152
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0077 0.0076
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.0001
Trypanosoma brucei prolyl oligopeptidase, putative 0.0721 0.3892 0.398
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0298 0.1523 0.1556
Schistosoma mansoni mitochondrial solute carrier 0.006 0.0192 0.0194
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.003 0.0024 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0141 0.0648 0.1602
Trypanosoma cruzi cysteine proteinase, putative 0.0314 0.1616 0.165
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0077 0.0076
Plasmodium falciparum plasmepsin IX 0.0114 0.0497 0.1629
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0035 0.0032
Echinococcus granulosus EF HAND 1 calcium binding site 0.006 0.0192 0.0194
Schistosoma mansoni neprilysin-2 (M13 family) 0.0046 0.0115 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0389 0.0395
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0415 0.2179 0.2227
Loa Loa (eye worm) cathepsin B 0.0591 0.3165 0.3165
Echinococcus multilocularis caspase 0.0098 0.0404 0.0411
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Schistosoma mansoni notch 0.0026 0.0004 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1594 0.8786 0.8987
Brugia malayi prolyl oligopeptidase family protein 0.021 0.1032 0.103
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0648 0.0661
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0072 0.0071
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.2179 0.2227
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0721 0.3892 1
Schistosoma mansoni caspase-7 (C14 family) 0.0118 0.0519 0.0528
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0524 0.2791 0.2853
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0035 0.0083
Giardia lamblia Cysteine protease 0.0141 0.0648 0.2039
Loa Loa (eye worm) hypothetical protein 0.0118 0.0519 0.0519
Echinococcus multilocularis Glycosyl transferase, family 35 0.0105 0.0444 0.0451
Onchocerca volvulus 0.006 0.0192 0.0194
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.006 0.0192 0.0601
Brugia malayi calpain family protein 1 0.1099 0.6014 0.6013
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.006 0.0192 0.047
Trypanosoma cruzi oligopeptidase b 0.0721 0.3892 0.398
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.0555 0.0565
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Onchocerca volvulus 0.0568 0.3035 0.3103
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0004 0.0001
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0077 0.0076
Schistosoma mansoni calmodulin related calcium binding protein 0.006 0.0192 0.0194
Trypanosoma brucei calpain, putative 0.0125 0.0555 0.0565
Brugia malayi Cell death protein 3 precursor 0.0118 0.0519 0.0516
Onchocerca volvulus 0.0157 0.0736 0.075
Echinococcus granulosus apoptotic protease activating factor 1 0.0092 0.0373 0.0378
Trichomonas vaginalis calcineurin B subunit, putative 0.006 0.0192 0.047
Entamoeba histolytica cysteine protease, putative 0.0141 0.0648 0.211
Brugia malayi Cathepsin L-like precursor 0.0568 0.3035 0.3033
Trypanosoma brucei protein I/6 0.006 0.0192 0.0194
Schistosoma mansoni hypothetical protein 0.0414 0.2177 0.2224
Onchocerca volvulus Prolyl endopeptidase homolog 0.1771 0.9775 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0098 0.0404 0.0411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Mycobacterium ulcerans zinc metalloprotease 0.0091 0.0369 0.0865
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0159 0.0745 0.2345
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Echinococcus multilocularis caspase 2 0.0118 0.0519 0.0528
Loa Loa (eye worm) hypothetical protein 0.0069 0.0244 0.0244
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0244 0.1223 0.1223
Brugia malayi calpain family protein 1 0.1099 0.6014 0.6013
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0192 0.047
Schistosoma mansoni cpg binding protein 0.006 0.0193 0.0195
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0591 0.3165 0.3236
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0077 0.0076
Leishmania major hypothetical protein, conserved 0.0061 0.0196 0.0198
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0039 0.0077 0.0184
Trichomonas vaginalis calmodulin, putative 0.0061 0.0196 0.048
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0159 0.0745 0.0759
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0077 0.0076
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0127 0.0567 0.0577
Trichomonas vaginalis calcineurin B subunit, putative 0.0061 0.0196 0.048
Loa Loa (eye worm) hypothetical protein 0.0157 0.0736 0.0736
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0721 0.3892 0.398
Echinococcus granulosus calpain A 0.116 0.6354 0.6499
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0568 0.3035 0.3103
Entamoeba histolytica cysteine protease, putative 0.0141 0.0648 0.211
Echinococcus multilocularis calpain 7 (C02 family) 0.0415 0.2179 0.2227
Chlamydia trachomatis glycogen phosphorylase 0.0105 0.0444 0.5
Plasmodium falciparum plasmepsin VIII, putative 0.003 0.0024 0.007
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0141 0.0648 0.2039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) hypothetical protein 0.1771 0.9775 0.9775
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0024 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Toxoplasma gondii calmodulin CAM1 0.0061 0.0196 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0444 0.0451
Loa Loa (eye worm) hypothetical protein 0.006 0.0192 0.0192
Schistosoma mansoni hypothetical protein 0.006 0.0192 0.0194
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Brugia malayi carbohydrate phosphorylase 0.0105 0.0444 0.0441
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0125 0.0555 0.0565
Echinococcus multilocularis fibropellin Ia 0.0026 0.0004 0.0001
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.007 0.0249 0.0253
Loa Loa (eye worm) hypothetical protein 0.0141 0.0648 0.0648
Echinococcus granulosus endothelin converting enzyme 1 0.0091 0.0369 0.0374
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0141 0.0648 0.0661
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0591 0.3165 0.7848
Plasmodium falciparum plasmepsin III 0.003 0.0024 0.007
Trypanosoma cruzi cysteine protease, putative 0.0314 0.1616 0.165
Onchocerca volvulus 0.007 0.0249 0.0253
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.2179 0.2227
Echinococcus multilocularis calpain 5 0.0415 0.2179 0.2227
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0625 0.1545
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.0001
Echinococcus multilocularis EF HAND 1, calcium binding site 0.006 0.0192 0.0194
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Entamoeba histolytica grainin, putative 0.0061 0.0196 0.0615
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0125 0.0555 0.0565
Onchocerca volvulus 0.0061 0.0196 0.0198
Giardia lamblia Alanyl dipeptidyl peptidase 0.021 0.1032 0.3254
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0125 0.0555 0.0565
Trypanosoma brucei calpain-like protein, putative 0.0415 0.2179 0.2227
Loa Loa (eye worm) hypothetical protein 0.0091 0.0369 0.0369
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0047 0.0119 0.0119
Brugia malayi Animal haem peroxidase family protein 0.0321 0.1655 0.1653
Brugia malayi Ets-domain containing protein 0.007 0.025 0.0248
Leishmania major protein kinase, putative 0.006 0.0192 0.0194
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0035 0.0033
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0035 0.008
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0125 0.0555 0.0565
Entamoeba histolytica calmodulin, putative 0.006 0.0192 0.0601
Echinococcus multilocularis notch 0.0026 0.0004 0.0001
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.001 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0035 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2067 0.5124
Leishmania major calmodulin-like protein 0.006 0.0192 0.0194
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0524 0.2791 0.2853
Entamoeba histolytica grainin 2 0.006 0.0192 0.0601
Onchocerca volvulus Cell death protein 3 homolog 0.0118 0.0519 0.0528
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.0001
Schistosoma mansoni calpain-2 (C02 family) 0.0125 0.0555 0.0565
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0124 0.0551 0.0561
Plasmodium falciparum plasmepsin I 0.003 0.0024 0.007
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0151 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0141 0.0648 0.1602
Toxoplasma gondii aspartyl protease ASP3 0.0114 0.0497 0.0506
Loa Loa (eye worm) hypothetical protein 0.0173 0.0824 0.0824
Entamoeba histolytica cysteine proteinase, putative 0.0314 0.1616 0.5308
Giardia lamblia Hypothetical protein 0.0124 0.0551 0.1733
Echinococcus granulosus protein jagged 2 0.0026 0.0004 0.0001
Brugia malayi Cadherin domain containing protein 0.0026 0.0004 0.0001
Schistosoma mansoni caspase-3 (C14 family) 0.0098 0.0404 0.0411
Onchocerca volvulus 0.0568 0.3035 0.3103
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0151 0.0152
Echinococcus multilocularis flap endonuclease 1 0.0027 0.001 0.0008
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0035 0.0033
Echinococcus multilocularis prolyl endopeptidase 0.1771 0.9775 1
Brugia malayi Fli-1 protein 0.0213 0.1052 0.1049
Giardia lamblia Cathepsin B precursor 0.0141 0.0648 0.2039
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0721 0.3892 0.398
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1099 0.6014 0.6151
Brugia malayi programmed cell death protein 6 0.006 0.0192 0.0189
Echinococcus multilocularis survival motor neuron protein 1 0.0248 0.1247 0.1273
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0115 0.0115
Giardia lamblia Cysteine protease 0.0141 0.0648 0.2039
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0047 0.0119 0.0384
Plasmodium falciparum plasmepsin V 0.003 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0141 0.0648 0.0648
Brugia malayi aspartic protease BmAsp-1, identical 0.003 0.0024 0.0021
Loa Loa (eye worm) fli-1 protein 0.0213 0.1052 0.1052
Plasmodium vivax calpain, putative 0.0415 0.2179 0.7178
Loa Loa (eye worm) hypothetical protein 0.0173 0.0824 0.0824
Echinococcus granulosus prolyl endopeptidase 0.1771 0.9775 1
Onchocerca volvulus 0.0046 0.0115 0.0115
Schistosoma mansoni reticulocalbin 0.0061 0.0196 0.0198
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1159 0.635 0.6494
Echinococcus multilocularis Mastin 0.007 0.0249 0.0253
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Brugia malayi hypothetical protein 0.003 0.0024 0.0021
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0077 0.0076
Brugia malayi Trypsin family protein 0.007 0.0249 0.0247
Schistosoma mansoni centrin 0.006 0.0192 0.0194
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0141 0.0648 0.2129
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Schistosoma mansoni notch 0.0027 0.0005 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0035 0.0107
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0144 0.0145
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.021 0.1032 0.2555
Entamoeba histolytica cysteine protease, putative 0.0141 0.0648 0.211
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0072 0.0262 0.0265
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.0555 0.0565
Schistosoma mansoni microtubule-associated protein tau 0.1417 0.7794 0.7972
Plasmodium falciparum serine repeat antigen 5 0.0141 0.0648 0.2129
Leishmania major proteasome beta 2 subunit, putative 0.0047 0.0119 0.0119
Echinococcus granulosus Mastin 0.007 0.0249 0.0253
Echinococcus granulosus cathepsin l1 0.0395 0.2067 0.2113
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Schistosoma mansoni hypothetical protein 0.007 0.0249 0.0253
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Echinococcus granulosus proteasome prosome macropain 0.0159 0.0745 0.076
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1771 0.9775 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Onchocerca volvulus 0.0746 0.4034 0.4125
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Loa Loa (eye worm) aspartyl protease 6 0.003 0.0024 0.0024
Schistosoma mansoni notch 0.0026 0.0004 0.0001
Entamoeba histolytica cysteine proteinase 1, putative 0.0314 0.1616 0.5308
Brugia malayi proteasome subunit beta type 1 0.0072 0.0262 0.0259
Giardia lamblia Alanyl dipeptidyl peptidase 0.021 0.1032 0.3254
Onchocerca volvulus 0.007 0.0249 0.0253
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Echinococcus multilocularis calumenin 0.0061 0.0196 0.0198
Brugia malayi Trypsin family protein 0.007 0.0249 0.0247
Echinococcus granulosus caspase 0.0098 0.0404 0.0411
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0159 0.0745 0.0759
Onchocerca volvulus 0.0141 0.0648 0.0661
Trypanosoma brucei cysteine peptidase C (CPC) 0.0591 0.3165 0.3236
Plasmodium vivax vivapain-1 0.0314 0.1616 0.532
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0072 0.5
Onchocerca volvulus Peroxidasin homolog 0.0321 0.1655 0.1691
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0374 0.1951 0.1948
Trypanosoma brucei centrin, putative 0.006 0.0192 0.0194
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0004 0.0001
Giardia lamblia Cathepsin L-like protease 0.0141 0.0648 0.2039
Schistosoma mansoni gamma-secretase subunit aph-1 0.0244 0.1223 0.1248
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.1032 0.1053
Trypanosoma cruzi centrin, putative 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0125 0.0555 0.137
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0024
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Echinococcus multilocularis Regulator of G protein signaling 20 0.0039 0.0077 0.0076
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0568 0.3035 1
Brugia malayi cathepsin L precursor 0.0141 0.0648 0.0646
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Schistosoma mansoni memapsin-2 (A01 family) 0.0459 0.2429 0.2482
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0077 0.0074
Toxoplasma gondii cathepsin CPL 0.0568 0.3035 0.3103
Brugia malayi Delta serrate ligand family protein 0.0026 0.0004 0.0001
Schistosoma mansoni reticulocalbin 0.006 0.0192 0.0194
Trypanosoma brucei Calpain-like protein 1.2 0.0125 0.0555 0.0565
Onchocerca volvulus 0.0026 0.0004 0.0001
Onchocerca volvulus 0.0568 0.3035 0.3103
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0176 0.084 0.0838
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0077 0.0076
Brugia malayi Peptidase family M13 containing protein 0.0091 0.0369 0.0366
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0721 0.3892 0.398
Plasmodium vivax plasmepsin V, putative 0.003 0.0024 0.007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0389 0.0395
Onchocerca volvulus Chorion peroxidase homolog 0.0321 0.1655 0.1691
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0141 0.0648 0.1602
Loa Loa (eye worm) hypothetical protein 0.0068 0.0235 0.0235
Echinococcus granulosus neurogenic locus protein delta 0.0026 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0374 0.1951 0.1951
Brugia malayi cathepsin F-like cysteine proteinase 0.0141 0.0648 0.0646
Leishmania major cathepsin L-like protease 0.0664 0.3576 0.3656
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.036 0.0366
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0415 0.2179 0.2227
Echinococcus multilocularis protein jagged 1 0.0026 0.0004 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.006 0.0192 0.0194
Echinococcus granulosus Regulator of G protein signaling 20 0.0039 0.0077 0.0076
Leishmania major cathepsin L-like protease 0.0568 0.3035 0.3103
Echinococcus multilocularis transmembrane protease serine 3 0.007 0.0249 0.0253
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0035 0.0033
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0072 0.0071
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0035 0.0033
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0176 0.084 0.0838
Entamoeba histolytica cysteine proteinase, putative 0.0314 0.1616 0.5308
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0077 0.0076
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0125 0.0555 0.0565
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0072 0.5
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0444 0.0451
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0508 0.0508
Loa Loa (eye worm) hypothetical protein 0.0068 0.0235 0.0235
Echinococcus granulosus calpain 0.0415 0.2179 0.2227
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0721 0.3892 0.4504
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.036 0.0366
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0004 0.0001
Loa Loa (eye worm) calpain 5 0.029 0.1481 0.1481
Brugia malayi prolyl oligopeptidase family protein 0.0298 0.1523 0.1521
Toxoplasma gondii centrin, putative 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Echinococcus granulosus slit 2 protein 0.0026 0.0004 0.0001
Echinococcus granulosus calpain A 0.0415 0.2179 0.2227
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Trichomonas vaginalis centrin, putative 0.006 0.0192 0.047
Schistosoma mansoni gabp alpha 0.007 0.025 0.0253
Giardia lamblia Cathepsin L precursor 0.0141 0.0648 0.2039
Loa Loa (eye worm) hypothetical protein 0.0173 0.0824 0.0824
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0047 0.0119 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0314 0.1616 0.4003
Entamoeba histolytica prolyl oligopeptidase family protein 0.021 0.1032 0.3379
Leishmania major kinesin, putative 0.029 0.1481 0.1512
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Echinococcus granulosus centrin 2 0.006 0.0192 0.0194
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0141 0.0648 0.2039
Loa Loa (eye worm) hypothetical protein 0.0395 0.2067 0.2067
Loa Loa (eye worm) calmodulin-like protein 0.006 0.0192 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0184
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0127 0.0124
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0061 0.0196 0.0198
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trypanosoma cruzi calmodulin, putative 0.006 0.0192 0.0194
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.001 0.0018
Brugia malayi prolyl oligopeptidase family protein 0.1771 0.9775 0.9775
Brugia malayi calpain 5 0.0125 0.0555 0.0552
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Onchocerca volvulus 0.0568 0.3035 0.3103
Echinococcus multilocularis calcium uptake protein 1 0.0061 0.0196 0.0198
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0035 0.0033
Toxoplasma gondii aldehyde dehydrogenase 0.0127 0.0567 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Echinococcus multilocularis cysteine protease 0.0568 0.3035 0.3103
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0077 0.0074
Leishmania major oligopeptidase b 0.0721 0.3892 0.398
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0047 0.0119 0.0119
Echinococcus multilocularis cathepsin L 0.0141 0.0648 0.0661
Echinococcus multilocularis calbindin 32 0.0061 0.0196 0.0198
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0001
Trypanosoma brucei I/6 autoantigen 0.006 0.0192 0.0194
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.006 0.0192 0.0601
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.036 0.0366
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0091 0.0369 0.0366
Schistosoma mansoni neuronal calcium sensor 0.006 0.0192 0.0194
Echinococcus multilocularis cathepsin L 0.0314 0.1616 0.1651
Echinococcus multilocularis cathepsin L cysteine protease 0.0568 0.3035 0.3103
Schistosoma mansoni chromatin regulatory protein sir2 0.0137 0.0625 0.0637
Brugia malayi hypothetical protein 0.0092 0.0373 0.037
Trypanosoma cruzi cysteine peptidase, putative 0.0664 0.3576 0.3656
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.025 0.0253
Echinococcus granulosus endonuclease exonuclease phosphatase 0.019 0.092 0.0938
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.036 0.0366
Brugia malayi aspartic protease BmAsp-2, identical 0.003 0.0024 0.0021
Plasmodium vivax proteasome subunit beta type-5, putative 0.0159 0.0745 0.2448
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0072 0.0172
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0077 0.0076
Schistosoma mansoni ef hand domain family member A2 0.006 0.0192 0.0194
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Trichomonas vaginalis calcium binding protein, putative 0.006 0.0192 0.047
Loa Loa (eye worm) hypothetical protein 0.0069 0.0244 0.0244
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Loa Loa (eye worm) hypothetical protein 0.0069 0.0244 0.0244
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Plasmodium falciparum serine repeat antigen 6 0.0141 0.0648 0.2129
Loa Loa (eye worm) hypothetical protein 0.0048 0.0127 0.0127
Brugia malayi fibroinase precursor 0.0141 0.0648 0.0646
Loa Loa (eye worm) hypothetical protein 0.0105 0.0447 0.0447
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0035 0.0083
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0001
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0314 0.1616 0.165
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Schistosoma mansoni notch 0.0026 0.0004 0.0001
Toxoplasma gondii EGF family domain-containing protein 0.0026 0.0004 0.0001
Brugia malayi Proteasome A-type and B-type family protein 0.0159 0.0745 0.0742
Loa Loa (eye worm) sirtuin 4 0.0032 0.0035 0.0035
Leishmania major cytochrome p450-like protein 0.0033 0.0039 0.0037
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0035 0.008
Echinococcus granulosus transmembrane protease serine 3 0.007 0.0249 0.0253
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Plasmodium falciparum serine repeat antigen 7 0.0141 0.0648 0.2129
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0072 0.0262 0.0265
Plasmodium vivax aspartyl protease, putative 0.0114 0.0497 0.1629
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0591 0.3165 0.3236
Brugia malayi Ets-domain containing protein 0.007 0.025 0.0248
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0003
Echinococcus multilocularis EF hand domain containing family member A2 0.0061 0.0196 0.0198
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0444 0.1094
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0137 0.0625 0.0637
Onchocerca volvulus 0.0321 0.1655 0.1691
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Trypanosoma cruzi cysteine peptidase, putative 0.0568 0.3035 0.3103
Loa Loa (eye worm) fibroinase 0.0568 0.3035 0.3035
Echinococcus granulosus chromatin regulatory protein sir2 0.0124 0.0551 0.0561
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0047 0.0119 0.0119
Echinococcus multilocularis hypothetical protein 0.0415 0.2179 0.2227
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0125 0.0555 0.137
Echinococcus multilocularis cpg binding protein 0.006 0.0193 0.0195
Schistosoma mansoni neuronal calcium sensor 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) hypothetical protein 0.0091 0.0369 0.0369
Brugia malayi Cathepsin L-like precursor 0.0568 0.3035 0.3033
Brugia malayi calcium-binding protein 0.006 0.0192 0.0189
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0141 0.0648 0.0648
Giardia lamblia Cathepsin B precursor 0.0141 0.0648 0.2039
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.0555 0.0565
Entamoeba histolytica prolyl oligopeptidase family protein 0.021 0.1032 0.3379
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0389 0.0395
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0567 0.1378
Plasmodium vivax proteasome subunit beta type-1, putative 0.0072 0.0262 0.0855
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0077
Onchocerca volvulus 0.0568 0.3035 0.3103
Trypanosoma cruzi cysteine peptidase, putative 0.0664 0.3576 0.3656
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0072 0.0095
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0072 0.0262 0.0265
Echinococcus granulosus cathepsin b 0.1594 0.8786 0.8987
Plasmodium falciparum proteasome subunit beta type-5 0.0159 0.0745 0.2448
Loa Loa (eye worm) hypothetical protein 0.0568 0.3035 0.3035
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Echinococcus multilocularis slit 2 protein 0.0026 0.0004 0.0001
Leishmania major sir2-family protein-like protein 0.0032 0.0035 0.0033
Schistosoma mansoni calpain-7 (C02 family) 0.0418 0.2196 0.2245
Onchocerca volvulus Deterin homolog 0.0176 0.084 0.0857
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0184
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Schistosoma mansoni peroxidasin 0.0321 0.1655 0.1691
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Trichomonas vaginalis calcium binding protein, putative 0.006 0.0192 0.047
Plasmodium vivax SET domain protein, putative 0.0095 0.0389 0.1273
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.006 0.0192 0.0194
Schistosoma mansoni hypothetical protein 0.0033 0.0041 0.0039
Entamoeba histolytica protein kinase, putative 0.029 0.1481 0.4863
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.021 0.1032 0.1053
Plasmodium falciparum peptidase, putative 0.021 0.1032 0.3395
Trypanosoma cruzi I/6 autoantigen, putative 0.006 0.0192 0.0194
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0046 0.0115 0.0115
Onchocerca volvulus Peroxidase homolog 0.0321 0.1655 0.1691
Trichomonas vaginalis conserved hypothetical protein 0.021 0.1032 0.2555
Leishmania major C-8 sterol isomerase-like protein 0.0374 0.1951 0.1993
Giardia lamblia Proteasome subunit beta type 1 0.0072 0.0262 0.0817
Entamoeba histolytica calcium-binding protein, putative 0.006 0.0192 0.0601
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0141 0.0648 0.1602
Echinococcus granulosus cysteine protease 0.0314 0.1616 0.1651
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0045 0.011 0.0195
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.019 0.092 0.0938
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Plasmodium vivax serine-repeat antigen (SERA) 0.0141 0.0648 0.2129
Echinococcus granulosus calbindin 32 0.0061 0.0196 0.0198
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Onchocerca volvulus Cathepsin L homolog 0.0568 0.3035 0.3103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0648 0.1602
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0568 0.3035 0.7525
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0648 0.0661
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0157 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0648 0.1602
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0314 0.1616 0.165
Echinococcus granulosus cathepsin l cysteine peptidase 0.0568 0.3035 0.3103
Trypanosoma brucei Calpain-like protein 1.1 0.0125 0.0555 0.0565
Echinococcus granulosus neural cadherin 0.0026 0.0004 0.0001
Trypanosoma cruzi cruzipain precursor, putative 0.0173 0.0824 0.084
Loa Loa (eye worm) hypothetical protein 0.007 0.0249 0.0249
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1594 0.8786 0.8987
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0159 0.0745 0.0745
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0141 0.0648 0.1602
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0141 0.0648 0.1602
Loa Loa (eye worm) cysteine protease 0.0568 0.3035 0.3035
Brugia malayi A-kinase anchor protein 10, precursor 0.0039 0.0077 0.0074
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Leishmania major i/6 autoantigen-like protein 0.006 0.0192 0.0194
Trypanosoma cruzi cruzipain precursor, putative 0.0664 0.3576 0.3656
Plasmodium falciparum plasmepsin X 0.0114 0.0497 0.1629
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0298 0.1523 0.1555
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0047 0.0119 0.0119
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0127 0.0567 0.0577
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0091 0.0369 0.0389
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0026 0.0004 0.0001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trichomonas vaginalis calcium binding proteins, putative 0.006 0.0192 0.047
Trypanosoma brucei Aph-1 protein, putative 0.0095 0.0389 0.0395
Brugia malayi Cathepsin L-like cysteine proteinase 0.0395 0.2067 0.2065
Plasmodium vivax proteasome subunit beta type-2, putative 0.0047 0.0119 0.0384
Loa Loa (eye worm) hypothetical protein 0.0069 0.0244 0.0244
Schistosoma mansoni survival motor neuron protein 0.0051 0.014 0.0141
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1159 0.635 0.6494
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0077 0.0076
Schistosoma mansoni hypothetical protein 0.0164 0.0776 0.0791
Trypanosoma brucei calpain-like protein, putative 0.0415 0.2179 0.2227
Plasmodium falciparum serine repeat antigen 2 0.0141 0.0648 0.2129
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0141 0.0648 0.2129
Giardia lamblia Encystation-specific protease 0.0141 0.0648 0.2039
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.006 0.0192 0.0194
Loa Loa (eye worm) hypothetical protein 0.0068 0.0235 0.0235
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0235 0.0235
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Echinococcus multilocularis gamma secretase subunit aph 1 0.0244 0.1223 0.1248
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0072 0.0262 0.0265
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0159 0.0745 0.1842
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0389 0.0395
Echinococcus multilocularis caspase 3 0.0072 0.0258 0.0261
Echinococcus granulosus sarcoplasmic calcium binding protein 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0141 0.0648 0.1602
Brugia malayi mbt repeat family protein 0.0046 0.0115 0.0112
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0035 0.0033
Entamoeba histolytica cysteine protease, putative 0.0568 0.3035 1
Trichomonas vaginalis myosin light chain 1, putative 0.006 0.0192 0.047
Loa Loa (eye worm) animal heme peroxidase 0.0321 0.1655 0.1655
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0077
Trypanosoma brucei calpain, putative 0.0125 0.0555 0.0565
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.0001
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.001 0.002
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0314 0.1616 0.1651
Plasmodium vivax unspecified product 0.0314 0.1616 0.532
Echinococcus granulosus tumor protein p63 0.0351 0.1822 0.1862
Echinococcus granulosus glycoprotein Antigen 5 0.007 0.0249 0.0253
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Onchocerca volvulus 0.0092 0.0373 0.0378
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0567 0.0577
Schistosoma mansoni cathepsin D (A01 family) 0.0128 0.0576 0.0586
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0125 0.0555 0.0565
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.006 0.0192 0.0194
Loa Loa (eye worm) hypothetical protein 0.0141 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Leishmania major hypothetical protein, conserved 0.0125 0.0555 0.0565
Giardia lamblia Cathepsin B precursor 0.0141 0.0648 0.2039
Brugia malayi mbt repeat family protein 0.0046 0.0115 0.0112
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0365 0.1901 0.1943
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0077 0.0076
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Entamoeba histolytica cysteine proteinase, putative 0.0314 0.1616 0.5308
Echinococcus multilocularis cathepsin b 0.1594 0.8786 0.8987
Echinococcus granulosus fibropellin Ia 0.0026 0.0004 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Entamoeba histolytica cysteine proteinase 2 0.0314 0.1616 0.5308
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0072 0.0262 0.0265
Leishmania major calmodulin-like protein 0.006 0.0192 0.0194
Onchocerca volvulus 0.0685 0.3691 0.3774
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1771 0.9775 1
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0035 0.0083
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0115 0.0115
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0389 0.0395
Brugia malayi Cathepsin L-like precursor 0.0568 0.3035 0.3033
Loa Loa (eye worm) hypothetical protein 0.0046 0.0115 0.0115
Echinococcus granulosus expressed protein 0.0767 0.415 0.4243
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0141 0.0648 0.2039
Echinococcus granulosus geminin 0.0164 0.0776 0.0791
Brugia malayi EF hand family protein 0.0061 0.0196 0.0193
Echinococcus granulosus cathepsin L cysteine protease 0.0314 0.1616 0.1651
Leishmania major cathepsin L-like protease 0.0568 0.3035 0.3103
Entamoeba histolytica dipeptidyl-peptidase, putative 0.021 0.1032 0.3379
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.007 0.0249 0.0253
Plasmodium vivax unspecified product 0.0141 0.0648 0.2129
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0039 0.0037
Brugia malayi CXXC zinc finger family protein 0.0057 0.0175 0.0172
Brugia malayi Cathepsin L-like precursor 0.0568 0.3035 0.3033
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.007 0.0249 0.0253
Echinococcus multilocularis proteasome (prosome, macropain) 0.0159 0.0745 0.076
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trypanosoma brucei centrin-3 0.006 0.0192 0.0194
Brugia malayi calpain D 0.0125 0.0555 0.0552
Toxoplasma gondii preprocathepsin c precursor, putative 0.0141 0.0648 0.066
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0159 0.0745 0.0759
Brugia malayi PXA domain containing protein 0.0039 0.0077 0.0074
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0077 0.0076
Trypanosoma cruzi I/6 autoantigen, putative 0.006 0.0192 0.0194
Brugia malayi prolyl oligopeptidase family protein 0.0524 0.2791 0.2789
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0176 0.084 0.0857
Toxoplasma gondii cathepsin CPC2 0.0141 0.0648 0.066
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.007 0.0249 0.0247
Brugia malayi Peroxidasin 0.0321 0.1655 0.1653
Brugia malayi Blistered cuticle protein 3 0.0321 0.1655 0.1653
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.021 0.1032 0.1053
Echinococcus multilocularis EF hand domain containing family member A2 0.006 0.0192 0.0194
Loa Loa (eye worm) prolyl oligopeptidase 0.021 0.1032 0.1032
Loa Loa (eye worm) hypothetical protein 0.0091 0.0369 0.0369
Entamoeba histolytica cysteine proteinase, putative 0.0395 0.2067 0.6801
Plasmodium vivax serine-repeat antigen (SERA) 0.0141 0.0648 0.2129
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0141 0.0648 0.211
Echinococcus multilocularis fat cadherin tumor suppressor 0.0026 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Giardia lamblia Cathepsin L precursor 0.0141 0.0648 0.2039
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0072 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0567 0.1378
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0035 0.008
Echinococcus granulosus cathepsin L 0.0314 0.1616 0.1651
Schistosoma mansoni glycogen phosphorylase 0.0045 0.011 0.011
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0568 0.3035 1
Plasmodium falciparum plasmepsin VI 0.003 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0144
Trichomonas vaginalis calmodulin-2, putative 0.006 0.0192 0.047
Echinococcus granulosus protein jagged 1 0.0026 0.0004 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Echinococcus granulosus GA binding protein alpha chain 0.007 0.025 0.0253
Schistosoma mansoni cathepsin F (C01 family) 0.0568 0.3035 0.3103
Echinococcus multilocularis expressed protein 0.0767 0.415 0.4243
Schistosoma mansoni septate junction protein 0.0026 0.0004 0.0001
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Brugia malayi Cathepsin L-like precursor 0.0568 0.3035 0.3033
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0091 0.0369 0.0374
Echinococcus multilocularis apoptotic protease activating factor 1 0.0092 0.0373 0.0378
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0235 0.0235
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0551 0.0561
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0004 0.0001
Loa Loa (eye worm) proteasome subunit beta type 2 0.0047 0.0119 0.0119
Brugia malayi hypothetical protein 0.007 0.0249 0.0247
Brugia malayi Papain family cysteine protease containing protein 0.0314 0.1616 0.1614
Brugia malayi Cathepsin L-like precursor 0.0568 0.3035 0.3033
Trypanosoma cruzi major cysteine proteinase, putative 0.0141 0.0648 0.066
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0568 0.3035 0.3103
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0077 0.0074
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.003 0.0024 0.0022
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.0555 0.0565
Entamoeba histolytica cysteine proteinase, putative 0.0568 0.3035 1
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0004 0.0001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Entamoeba histolytica calpain large subunit domain III containing protein 0.029 0.1481 0.4863
Loa Loa (eye worm) hypothetical protein 0.0685 0.3691 0.3691
Brugia malayi Animal haem peroxidase family protein 0.0321 0.1655 0.1653
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0192 0.047
Echinococcus granulosus Glycosyl transferase family 35 0.0105 0.0444 0.0451
Loa Loa (eye worm) hypothetical protein 0.006 0.0193 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0184
Plasmodium falciparum serine repeat antigen 9 0.0141 0.0648 0.2129
Loa Loa (eye worm) blistered cuticle protein 3 0.0321 0.1655 0.1655
Schistosoma mansoni cathepsin F (C01 family) 0.0568 0.3035 0.3103
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Brugia malayi Cytochrome P450 family protein 0.0033 0.0039 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0072 0.0172
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0151 0.0152
Toxoplasma gondii EF hand domain-containing protein 0.006 0.0192 0.0194
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0567 0.0577
Plasmodium vivax vivapain-2 0.0568 0.3035 1
Schistosoma mansoni neuronal calcium sensor 0.006 0.0192 0.0194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Echinococcus granulosus gamma secretase subunit aph 1 0.0244 0.1223 0.1248
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Brugia malayi Cathepsin L-like precursor 0.0395 0.2067 0.2065
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0125 0.0555 0.0565
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1594 0.8786 0.8987
Entamoeba histolytica cysteine protease, putative 0.0141 0.0648 0.211
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0077 0.0076
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0141 0.0648 0.0661
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0077 0.0076
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0115 0.0115
Onchocerca volvulus 0.0026 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0347 0.0347
Schistosoma mansoni Mername-AA248 (C02 family) 0.0415 0.2179 0.2227
Echinococcus granulosus delta-like protein 1 0.0026 0.0004 0.0001
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0047 0.0119 0.0289
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0141 0.0648 0.2129
Echinococcus granulosus calpain 7 C02 family 0.0415 0.2179 0.2227
Leishmania major cathepsin L-like protease 0.0664 0.3576 0.3656
Schistosoma mansoni cathepsin C 0.0141 0.0648 0.0661
Echinococcus multilocularis cysteine protease 0.0568 0.3035 0.3103
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0077 0.0076
Echinococcus granulosus Dipeptidyl peptidase 9 0.0298 0.1523 0.1556
Giardia lamblia Cathepsin L precursor 0.0141 0.0648 0.2039
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0077 0.0077
Brugia malayi hypothetical protein 0.0088 0.0347 0.0345
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0077 0.0076
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1159 0.635 0.6494
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0046 0.0115 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Echinococcus granulosus neurocalcin 0.006 0.0192 0.0194
Onchocerca volvulus Glycogen phosphorylase homolog 0.0105 0.0444 0.0451
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0051 0.014 0.0141
Loa Loa (eye worm) hypothetical protein 0.0095 0.0389 0.0389
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0124 0.0551 0.179
Brugia malayi notch-like transmembrane receptor 0.0026 0.0004 0.0001
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0072 0.0262 0.0643
Loa Loa (eye worm) animal heme peroxidase 0.0321 0.1655 0.1655
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0095 0.0389 0.0395
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.001 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.1417 0.7794 0.7972
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0072 0.0071
Brugia malayi Papain family cysteine protease containing protein 0.0141 0.0648 0.0646
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0141 0.0648 0.0661
Loa Loa (eye worm) programmed cell death protein 6 0.0061 0.0196 0.0196
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0591 0.3165 0.3236
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0444 0.0451
Toxoplasma gondii aspartyl protease 0.003 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0003
Schistosoma mansoni calmodulin 0.006 0.0192 0.0194
Leishmania major cathepsin L-like protease 0.0568 0.3035 0.3103
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0176 0.084 0.0857
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0314 0.1616 0.1651
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0298 0.1523 0.1555
Echinococcus multilocularis calmodulin 0.006 0.0192 0.0194
Brugia malayi Cytochrome P450 family protein 0.0054 0.0157 0.0155
Plasmodium vivax hypothetical protein, conserved 0.021 0.1032 0.3395
Entamoeba histolytica dipeptidyl-peptidase, putative 0.021 0.1032 0.3379
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0184
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.0035 0.0099
Onchocerca volvulus 0.007 0.0249 0.0253
Schistosoma mansoni cathepsin S (C01 family) 0.0141 0.0648 0.0661
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1594 0.8786 0.8987
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Loa Loa (eye worm) aspartic protease BmAsp-2 0.003 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0077
Plasmodium falciparum cysteine proteinase falcipain 1 0.0314 0.1616 0.532
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0061 0.0196 0.0198
Trypanosoma cruzi major cysteine proteinase, putative 0.0238 0.1189 0.1214
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0115 0.0115
Trichomonas vaginalis calcium binding protein, putative 0.006 0.0192 0.047
Onchocerca volvulus Putative cubilin 0.0026 0.0004 0.0001
Schistosoma mansoni inhibitor of apoptosis protein 0.0176 0.084 0.0857
Onchocerca volvulus 0.0568 0.3035 0.3103
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.006 0.0192 0.0194
Schistosoma mansoni hypothetical protein 0.0164 0.0776 0.0791
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Toxoplasma gondii calcium-dependent protein kinase 0.0061 0.0196 0.0198
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0141 0.0648 0.2129
Schistosoma mansoni cpg binding protein 0.006 0.0193 0.0195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0648 0.1602
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0039 0.0037
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0115 0.0115
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.003 0.0024 0.0053
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0003 0.0003
Trichomonas vaginalis calpain, putative 0.0125 0.0555 0.137
Schistosoma mansoni rab 0.006 0.0192 0.0194
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0551 0.0561
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.014 0.0137
Schistosoma mansoni calpain (C02 family) 0.0415 0.2179 0.2227
Schistosoma mansoni ap endonuclease 0.0038 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0395 0.2067 0.2067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Echinococcus multilocularis peroxidasin 0.0321 0.1655 0.1691
Echinococcus multilocularis protein jagged 1 0.0026 0.0004 0.0001
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0444 0.1094
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0072 0.0216
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1771 0.9775 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0249 0.0249
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0035 0.008
Loa Loa (eye worm) PXA domain-containing protein 0.0039 0.0077 0.0077
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0395 0.2067 0.2067
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0077 0.0077
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1159 0.635 0.6494
Trichomonas vaginalis calpain, putative 0.0125 0.0555 0.137
Plasmodium falciparum plasmepsin IV 0.003 0.0024 0.007
Onchocerca volvulus 0.0051 0.0144 0.0145
Schistosoma mansoni peroxidasin 0.0321 0.1655 0.1691
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0127 0.0127
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0077 0.0074
Echinococcus multilocularis neural cadherin 0.0026 0.0004 0.0001
Brugia malayi EF hand family protein 0.006 0.0192 0.0189
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0141 0.0648 0.2039
Leishmania major centrin, putative 0.006 0.0192 0.0194
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0001
Entamoeba histolytica hypothetical protein 0.0141 0.0648 0.211
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0115 0.0115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.036 0.0366
Brugia malayi cathepsin L-like cysteine proteinase 0.0141 0.0648 0.0646
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0001
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0068 0.0235 0.0235
Echinococcus granulosus dnaJ subfamily B 0.0414 0.2177 0.2224
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.001 0.0007
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0141 0.0648 0.2129
Giardia lamblia Cathepsin B precursor 0.0141 0.0648 0.2039
Onchocerca volvulus Slit protein homolog 0.0026 0.0004 0.0001
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0026 0.0004 0.0001
Trypanosoma brucei hypothetical protein 0.0125 0.0555 0.0565
Echinococcus granulosus cpg binding protein 0.006 0.0193 0.0195
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.021 0.1032 0.2555
Loa Loa (eye worm) hypothetical protein 0.0137 0.0625 0.0625
Leishmania major phospholipase c-like protein 0.006 0.0192 0.0194
Schistosoma mansoni hypothetical protein 0.006 0.0192 0.0194
Echinococcus multilocularis acylamino acid releasing enzyme 0.021 0.1032 0.1053
Plasmodium falciparum serine repeat antigen 3 0.0141 0.0648 0.2129
Leishmania major cathepsin L-like protease 0.0568 0.3035 0.3103
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.006 0.0192 0.047
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.003 0.0024 0.0022
Trypanosoma brucei mitochondrial calcium uptake 1 0.006 0.0192 0.0194
Echinococcus multilocularis geminin 0.0164 0.0776 0.0791
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0389 0.0395
Brugia malayi Papain family cysteine protease containing protein 0.0568 0.3035 0.3033
Trypanosoma cruzi cysteine proteinase, putative 0.0314 0.1616 0.165
Loa Loa (eye worm) MBCTL1 0.0053 0.0151 0.0151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Brugia malayi hypothetical protein 0.0157 0.0736 0.0733
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.036 0.0366
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0444 0.0451
Onchocerca volvulus Dual oxidase homolog 0.0321 0.1655 0.1691
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0176 0.084 0.084
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0072 0.0071
Trypanosoma cruzi centrin, putative 0.006 0.0192 0.0194
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0035 0.0107
Plasmodium vivax aspartyl protease, putative 0.0114 0.0497 0.1629
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Trypanosoma brucei calpain-like protein, putative 0.0415 0.2179 0.2227
Onchocerca volvulus Cathepsin L homolog 0.0141 0.0648 0.0661
Leishmania major cathepsin L-like protease 0.0664 0.3576 0.3656
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.007 0.0249 0.0249
Leishmania major centrin, putative,caltractin, putative 0.006 0.0192 0.0194
Echinococcus granulosus acylamino acid releasing enzyme 0.021 0.1032 0.1053
Schistosoma mansoni ets-related 0.0213 0.1052 0.1073
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0141 0.0648 0.2129
Brugia malayi Trypsin-like protease protein 5 0.007 0.0249 0.0247
Echinococcus multilocularis programmed cell death protein 0.006 0.0192 0.0194
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0047 0.0119 0.0289
Echinococcus multilocularis dnaJ subfamily B 0.0414 0.2177 0.2224
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0072 0.0262 0.0855
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Onchocerca volvulus 0.0321 0.1655 0.1691
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0141 0.0648 0.1602
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Loa Loa (eye worm) hypothetical protein 0.021 0.1032 0.1032
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0115 0.0115
Plasmodium falciparum centrin-1 0.006 0.0192 0.0624
Brugia malayi cathepsin Z-like cysteine proteinase 0.0141 0.0648 0.0646
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0444 0.1434
Trypanosoma cruzi 20S proteasome subunit 0.0047 0.0119 0.0119
Trypanosoma cruzi kinesin, putative 0.029 0.1481 0.1512
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.0555 0.0565
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.036 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0648 0.1602
Trypanosoma cruzi cysteine peptidase, putative 0.0664 0.3576 0.3656
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0077 0.0076
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1811 1 1
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0004 0.0001
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0365 0.1901 0.1943
Trypanosoma brucei caltractin, putative 0.006 0.0192 0.0194
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0035 0.0107
Plasmodium falciparum serine repeat antigen 4 0.0141 0.0648 0.2129
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Schistosoma mansoni cathepsin s 0.0173 0.0824 0.084
Plasmodium vivax unspecified product 0.0173 0.0824 0.2708
Giardia lamblia Cysteine protease 0.0141 0.0648 0.2039
Onchocerca volvulus Peroxidasin homolog 0.0321 0.1655 0.1691
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.0001
Onchocerca volvulus 0.0026 0.0004 0.0001
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0625 0.1545
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0041 0.0039
Onchocerca volvulus Peroxidase homolog 0.0321 0.1655 0.1691
Brugia malayi Calmodulin-like protein 0.006 0.0192 0.0189
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0077 0.0076
Toxoplasma gondii prolyl endopeptidase 0.1771 0.9775 1
Giardia lamblia Cathepsin L-like protease 0.0141 0.0648 0.2039
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0141 0.0648 0.2129
Trypanosoma brucei antigen, putative 0.0415 0.2179 0.2227
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.021 0.1032 0.1053
Loa Loa (eye worm) animal heme peroxidase 0.0321 0.1655 0.1655
Schistosoma mansoni hypothetical protein 0.0289 0.1473 0.1504
Plasmodium falciparum plasmepsin II 0.003 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0039 0.0077 0.0076
Schistosoma mansoni centrin-related 0.006 0.0192 0.0194
Brugia malayi Muscle positioning protein 4 0.0026 0.0004 0.0001
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0098 0.0404 0.0411
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0077
Echinococcus granulosus flap endonuclease 1 0.0027 0.001 0.0008
Loa Loa (eye worm) RGS-3 protein 0.0039 0.0077 0.0077
Leishmania major cathepsin L-like protease 0.0568 0.3035 0.3103
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Loa Loa (eye worm) glycogen phosphorylase 0.0105 0.0444 0.0444
Plasmodium falciparum serine repeat antigen 1 0.0141 0.0648 0.2129
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0035 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.0555 0.0565
Loa Loa (eye worm) hypothetical protein 0.1594 0.8786 0.8786
Onchocerca volvulus 0.0026 0.0004 0.0001
Brugia malayi hypothetical protein 0.0321 0.1655 0.1653
Echinococcus granulosus neuronal calcium sensor 0.006 0.0192 0.0194
Echinococcus multilocularis cathepsin b 0.1594 0.8786 0.8987
Echinococcus multilocularis calpain family protein 1, d 0.0809 0.4389 0.4489
Brugia malayi hypothetical protein 0.0248 0.1247 0.1245
Giardia lamblia Sirtuin type 2 0.0032 0.0035 0.0099
Leishmania major calpain protease-like protein 0.0125 0.0555 0.0565
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Trichomonas vaginalis hypothetical protein 0.0125 0.0555 0.137
Loa Loa (eye worm) hypothetical protein 0.0045 0.011 0.011
Loa Loa (eye worm) transcriptional regulator 0.0124 0.0551 0.0551
Onchocerca volvulus 0.0321 0.1655 0.1691
Entamoeba histolytica hypothetical protein, conserved 0.0061 0.0196 0.0615
Schistosoma mansoni hypothetical protein 0.007 0.0249 0.0253
Onchocerca volvulus 0.0395 0.2067 0.2113
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Trypanosoma cruzi centrin-3 0.006 0.0192 0.0194
Brugia malayi Animal haem peroxidase family protein 0.0321 0.1655 0.1653
Schistosoma mansoni cathepsin B (C01 family) 0.0141 0.0648 0.0661
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0298 0.1523 0.1555
Echinococcus granulosus neurogenic locus notch protein 4 0.0026 0.0004 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0039 0.0039
Echinococcus multilocularis tumor protein p63 0.0351 0.1822 0.1862
Entamoeba histolytica cysteine proteinase, putative 0.0314 0.1616 0.5308
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0039 0.0037
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0072 0.0069
Leishmania major calmodulin, putative 0.006 0.0192 0.0194
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0039 0.0077 0.0221
Brugia malayi Pre-SET motif family protein 0.0655 0.3526 0.3524
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0124 0.0551 0.0561
Echinococcus multilocularis cathepsin L cysteine protease 0.0568 0.3035 0.3103
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0024 0.007
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0568 0.3035 0.3035
Echinococcus granulosus protein jagged 2 0.0026 0.0004 0.0001
Toxoplasma gondii aspartyl protease ASP1 0.003 0.0024 0.0022
Echinococcus multilocularis programmed cell death protein 0.006 0.0192 0.0194
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0141 0.0648 0.2129
Leishmania major calcineurin B subunit, putative 0.006 0.0192 0.0194
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Brugia malayi regulator of G-protein signaling rgs-7 0.0039 0.0077 0.0074
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.025 0.025
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Giardia lamblia Proteasome subunit beta type 2 0.0047 0.0119 0.0366
Loa Loa (eye worm) hypothetical protein 0.007 0.0249 0.0249
Plasmodium vivax plasmepsin IV, putative 0.003 0.0024 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.0648 0.1602
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0035 0.0033
Trypanosoma brucei Component of motile flagella 41 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0125 0.0555 0.137
Echinococcus granulosus calcium uptake protein 1 0.0061 0.0196 0.0198
Echinococcus granulosus calmodulin 0.006 0.0192 0.0194
Trypanosoma brucei cysteine peptidase, putative 0.0125 0.0555 0.0565
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.001 0.001
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0077 0.0076
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0115 0.0115
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Onchocerca volvulus 0.0568 0.3035 0.3103
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0141 0.0648 0.211
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0127 0.0124
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0039 0.0077 0.0076
Echinococcus granulosus cathepsin b 0.1594 0.8786 0.8987
Entamoeba histolytica hypothetical protein 0.0039 0.0077 0.0221
Echinococcus multilocularis endothelin converting enzyme 1 0.0091 0.0369 0.0374
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Brugia malayi hypothetical protein 0.0039 0.0077 0.0074
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0196 0.0637
Echinococcus granulosus calpain 5 0.0415 0.2179 0.2227
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1561 0.86 1
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0035 0.0033
Echinococcus granulosus caspase 2 0.0118 0.0519 0.0528
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0047 0.0119 0.0119
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Leishmania major centrin, putative 0.006 0.0192 0.0194
Schistosoma mansoni cell polarity protein 0.0026 0.0004 0.0001
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.006 0.0192 0.0194
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0125 0.0555 0.137
Echinococcus multilocularis calpain 0.0415 0.2179 0.2227
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1594 0.8786 0.8987
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Trichomonas vaginalis centrin, putative 0.006 0.0192 0.047
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0137 0.0625 0.1967
Schistosoma mansoni cpg binding protein 0.0057 0.0175 0.0176
Giardia lamblia Hypothetical protein 0.0141 0.0648 0.2039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Loa Loa (eye worm) calpain family protein 1 0.1099 0.6014 0.6014
Echinococcus granulosus cathepsin l1 0.0568 0.3035 0.3103
Brugia malayi MH2 domain containing protein 0.0116 0.0508 0.0505
Leishmania major proteasome beta 5 subunit, putative 0.0159 0.0745 0.0759
Brugia malayi calpain 5 0.029 0.1481 0.1479
Giardia lamblia Cathepsin B precursor 0.0591 0.3165 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0173 0.0824 0.0822
Onchocerca volvulus 0.0095 0.0389 0.0395
Brugia malayi transcriptional regulator, Sir2 family protein 0.0124 0.0551 0.0549
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0141 0.0648 0.0646
Giardia lamblia Hypothetical protein 0.0141 0.0648 0.2039
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0004 0.0001
Onchocerca volvulus Cathepsin L homolog 0.0568 0.3035 0.3103
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0077 0.0076
Echinococcus granulosus survival motor neuron protein 1 0.0248 0.1247 0.1273
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Toxoplasma gondii hypothetical protein 0.021 0.1032 0.1053
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0077 0.0076
Onchocerca volvulus 0.003 0.0024 0.0022
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0159 0.0745 0.076
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0173 0.0824 0.0824
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0568 0.3035 0.7525
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0039 0.0039
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0141 0.0648 0.0661
Echinococcus granulosus caspase 3 0.0072 0.0258 0.0261
Brugia malayi calpain 7 0.0415 0.2179 0.2177
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0072 0.0043
Trypanosoma cruzi kinesin, putative 0.029 0.1481 0.1512
Loa Loa (eye worm) calpain 0.0415 0.2179 0.2179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.006 0.0192 0.0194
Entamoeba histolytica calpain family cysteine protease, putative 0.0125 0.0555 0.1801
Trypanosoma cruzi calmodulin, putative 0.006 0.0192 0.0194
Leishmania major calmodulin, putative 0.006 0.0192 0.0194
Trypanosoma brucei kinesin, putative 0.029 0.1481 0.1512
Brugia malayi Papain family cysteine protease containing protein 0.0141 0.0648 0.0646
Entamoeba histolytica cysteine protease, putative 0.0141 0.0648 0.211
Brugia malayi cathepsin Z-like cysteine proteinase 0.0141 0.0648 0.0646
Onchocerca volvulus Neurogenic locus notch homolog 0.0027 0.0005 0.0002
Onchocerca volvulus 0.0051 0.014 0.0141
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0137 0.0625 0.0637
Trypanosoma cruzi cysteine peptidase, putative 0.0314 0.1616 0.165
Echinococcus granulosus EF hand domain containing family member A2 0.0061 0.0196 0.0198
Echinococcus multilocularis neurogenic locus notch protein 4 0.0026 0.0004 0.0001
Echinococcus multilocularis inhibitor of apoptosis protein 0.0176 0.084 0.0857
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0415 0.2179 0.2227
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2067 0.5124
Echinococcus granulosus EF hand domain containing family member A2 0.006 0.0192 0.0194
Echinococcus multilocularis glycoprotein Antigen 5 0.007 0.0249 0.0253
Brugia malayi PXA domain containing protein 0.0039 0.0077 0.0074
Loa Loa (eye worm) hypothetical protein 0.0809 0.4389 0.4389
Loa Loa (eye worm) calpain family protein 1 0.0809 0.4389 0.4389
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0175 0.0175
Schistosoma mansoni hypothetical protein 0.0176 0.084 0.0857
Schistosoma mansoni hypothetical protein 0.0092 0.0373 0.0378
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0141 0.0648 0.0648
Trichomonas vaginalis set domain proteins, putative 0.0746 0.4032 1
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0365 0.1901 0.1943
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0125 0.0555 0.0565
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0125 0.0555 0.137
Echinococcus granulosus protein jagged 1 0.0026 0.0004 0.0001
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0004 0.0001
Leishmania major hypothetical protein, conserved 0.006 0.0192 0.0194
Schistosoma mansoni cathepsin F (C01 family) 0.0395 0.2067 0.2113
Loa Loa (eye worm) notch protein 0.0026 0.0004 0.0004
Plasmodium falciparum plasmepsin VII 0.003 0.0024 0.007
Trypanosoma brucei prolyl endopeptidase 0.1771 0.9775 1
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0039 0.0009
Giardia lamblia Cathepsin L precursor 0.0141 0.0648 0.2039
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0801 0.4344 0.4442
Brugia malayi Papain family cysteine protease containing protein 0.0141 0.0648 0.0646
Brugia malayi Pre-SET motif family protein 0.0095 0.0389 0.0386
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0444 0.0451
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0567 0.1378
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0568 0.3035 0.7525
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0141 0.0648 0.1602
Giardia lamblia Cathepsin L precursor 0.0141 0.0648 0.2039
Mycobacterium ulcerans hypothetical protein 0.007 0.0249 0.0556
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0415 0.2179 0.2227
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0568 0.3035 0.3035
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0047 0.0119 0.0119
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0625 0.1545
Echinococcus granulosus enteropeptidase 0.007 0.0249 0.0253
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0035 0.0033
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0035 0.0033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0389 0.0395
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0004 0.0001
Plasmodium vivax aspartyl protease, putative 0.003 0.0024 0.007
Brugia malayi cathepsin B-like cysteine proteinase 0.1594 0.8786 0.8785
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0298 0.1523 0.1556
Entamoeba histolytica hypothetical protein, conserved 0.021 0.1032 0.3379
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0045 0.011 0.0088
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0141 0.0648 0.2129
Echinococcus granulosus cathepsin L 0.0141 0.0648 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0184
Schistosoma mansoni cercarial elastase (S01 family) 0.007 0.0249 0.0253
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0115 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0648 0.1602
Trichomonas vaginalis calcium binding protein, putative 0.006 0.0192 0.047
Leishmania major cysteine peptidase A (CPA) 0.0568 0.3035 0.3103
Toxoplasma gondii proteasome subunit beta type, putative 0.0159 0.0745 0.0759
Loa Loa (eye worm) hypothetical protein 0.0176 0.084 0.084
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0072 0.0262 0.0265
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0124 0.0551 0.179
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0141 0.0648 0.1602
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0648 0.0661
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.006 0.0192 0.0194
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.0001
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.001 0.0007
Brugia malayi Animal haem peroxidase family protein 0.0321 0.1655 0.1653
Toxoplasma gondii cathepsin CPC1 0.0141 0.0648 0.066
Onchocerca volvulus 0.006 0.0192 0.0194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0664 0.3576 0.3656
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.036 0.036
Loa Loa (eye worm) ctsf protein 0.0568 0.3035 0.3035
Trypanosoma brucei oligopeptidase b 0.0721 0.3892 0.398
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0004 0.0001
Onchocerca volvulus 0.007 0.0249 0.0253
Trypanosoma brucei Calpain-like protein 2 0.0125 0.0555 0.0565
Schistosoma mansoni calpain C (C02 family) 0.0415 0.2179 0.2227
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0072 0.0228
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0298 0.1523 0.1555
Loa Loa (eye worm) EF hand family protein 0.006 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.007 0.0249 0.0249
Brugia malayi EGF-like domain containing protein 0.0026 0.0004 0.0001
Echinococcus multilocularis regulator of G protein signaling 0.0039 0.0077 0.0076
Onchocerca volvulus 0.007 0.0249 0.0253
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0127 0.0567 0.0577
Entamoeba histolytica glycogen phosphorylase, putative 0.0045 0.011 0.0332
Toxoplasma gondii peptidase family M13 protein 0.0091 0.0369 0.0374
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0508 0.0508
Echinococcus granulosus notch 0.0026 0.0004 0.0001
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.006 0.0192 0.0194
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0648 0.0661
Plasmodium vivax vivapain-2 0.0568 0.3035 1
Schistosoma mansoni calpain-7 (C02 family) 0.0418 0.2196 0.2245
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0552 0.0562
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.003 0.0024 0.0022
Loa Loa (eye worm) proteasome subunit beta type 1 0.0072 0.0262 0.0262
Loa Loa (eye worm) aspartic protease BmAsp-1 0.003 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0069 0.0244 0.0244
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0026 0.0004 0.0001
Brugia malayi Cytochrome P450 family protein 0.0033 0.0039 0.0036
Echinococcus granulosus cathepsin L cysteine proteinase 0.0568 0.3035 0.3103
Giardia lamblia Cysteine protease 0.0141 0.0648 0.2039
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0184
Trypanosoma brucei centrin, putative 0.006 0.0192 0.0194
Brugia malayi Animal haem peroxidase family protein 0.0321 0.1655 0.1653
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0173 0.0824 0.0822
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0159 0.0745 0.243
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.006 0.0192 0.0624
Plasmodium vivax centrin-1, putative 0.006 0.0192 0.0624
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0072 0.0072
Trichomonas vaginalis calmodulin, putative 0.006 0.0192 0.047
Loa Loa (eye worm) hypothetical protein 0.0069 0.0244 0.0244
Entamoeba histolytica cysteine proteinase, putative 0.0568 0.3035 1
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.1032 0.1053
Trypanosoma brucei calmodulin, putative 0.0061 0.0196 0.0198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0314 0.1616 0.165
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0444 0.0451
Schistosoma mansoni hypothetical protein 0.0125 0.0555 0.0565
Trypanosoma brucei C-8 sterol isomerase, putative 0.0374 0.1951 0.1993
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0141 0.0648 0.2129
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Trypanosoma brucei proteasome beta 6 subunit 0.0072 0.0262 0.0265
Entamoeba histolytica glycogen phosphorylase, putative 0.0045 0.011 0.0332
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.007 0.0249 0.0253
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0141 0.0648 0.2129
Brugia malayi cathepsin L-like precursor 0.0395 0.2067 0.2065
Brugia malayi Cadherin domain containing protein 0.0026 0.0004 0.0001
Giardia lamblia Hypothetical protein 0.0061 0.0196 0.0609
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0077 0.0076
Leishmania major silent information regulator 2, putative 0.0124 0.0551 0.0561
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0141 0.0648 0.0648
Trypanosoma cruzi conserved protein 0.0125 0.0555 0.0565
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0298 0.1523 0.1555
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0072 0.0262 0.0265
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.0551 0.0561
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0125 0.0555 0.137
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0035 0.0107
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.007 0.0249 0.0253
Toxoplasma gondii hypothetical protein 0.0125 0.0555 0.0565
Entamoeba histolytica prolyl oligopeptidase family protein 0.021 0.1032 0.3379
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0551 0.0561
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0035 0.0033
Loa Loa (eye worm) animal heme peroxidase 0.0321 0.1655 0.1655
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0362 0.0368
Brugia malayi Flap endonuclease-1 0.0027 0.001 0.0007
Trypanosoma brucei Calpain-like protein CALP1.3 0.0125 0.0555 0.0565
Brugia malayi Eukaryotic aspartyl protease family protein 0.003 0.0024 0.0021
Trypanosoma brucei calpain-like protein, putative 0.0415 0.2179 0.2227
Loa Loa (eye worm) hypothetical protein 0.0141 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0491 0.2608 0.2666
Toxoplasma gondii cathepsin B 0.0591 0.3165 0.3236
Plasmodium falciparum flap endonuclease 1 0.0027 0.001 0.0024
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.048 0.0488
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.0555 0.0565
Trypanosoma cruzi caltractin, putative 0.006 0.0192 0.0194
Trypanosoma brucei calmodulin, putative 0.006 0.0192 0.0194
Trypanosoma cruzi oligopeptidase b 0.0721 0.3892 0.398
Plasmodium vivax vivapain-3 0.0314 0.1616 0.532
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0004
Echinococcus multilocularis chromatin regulatory protein sir2 0.0124 0.0551 0.0561
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0721 0.3892 0.398
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.0551 0.1361
Brugia malayi Papain family cysteine protease containing protein 0.0314 0.1616 0.1614
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0124 0.0551 0.0561
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0004 0.0001
Brugia malayi Cathepsin L-like precursor 0.0395 0.2067 0.2065
Onchocerca volvulus 0.0045 0.011 0.011
Entamoeba histolytica glycogenphosphorylase, putative 0.0045 0.011 0.0332
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0444 0.1434
Brugia malayi NAD-dependent deacetylase SIRT1 0.0137 0.0625 0.0623
Echinococcus multilocularis centrin 2 0.006 0.0192 0.0194
Leishmania major programmed cell death 6 protein-like protein 0.006 0.0192 0.0194
Schistosoma mansoni hypothetical protein 0.0026 0.0004 0.0001
Echinococcus granulosus microtubule associated protein 2 0.1417 0.7794 0.7972
Onchocerca volvulus 0.0026 0.0004 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0648 0.0661
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0314 0.1616 0.4003
Echinococcus multilocularis enteropeptidase 0.007 0.0249 0.0253
Schistosoma mansoni calmodulin 0.006 0.0192 0.0194
Plasmodium falciparum calpain 0.0125 0.0555 0.182
Loa Loa (eye worm) hypothetical protein 0.0248 0.1247 0.1247
Entamoeba histolytica cysteine protease, putative 0.0314 0.1616 0.5308
Leishmania major calpain family cysteine protease-like protein 0.0125 0.0555 0.0565
Onchocerca volvulus 0.007 0.0249 0.0253
Schistosoma mansoni cathepsin D (A01 family) 0.0128 0.0576 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.1099 0.6014 0.6014
Loa Loa (eye worm) hypothetical protein 0.0321 0.1655 0.1655

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) 0 Inhibition of HCV RNA replication by replicon assay ChEMBL. 16908138
IC50 (binding) > 100 uM Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPA ChEMBL. 16908138
IC50 (binding) > 100 uM Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPA ChEMBL. 16908138

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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