Detailed information for compound 413140

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 426.294 | Formula: C14H8F6N4O3S
  • H donors: 0 H acceptors: 4 LogP: 2.3 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccc(cc1C(F)(F)F)N1C(=O)[C@]2(N(S1(=O)=O)N=C(C2)C(F)(F)F)C
  • InChi: 1S/C14H8F6N4O3S/c1-12-5-10(14(18,19)20)22-24(12)28(26,27)23(11(12)25)8-3-2-7(6-21)9(4-8)13(15,16)17/h2-4H,5H2,1H3/t12-/m0/s1
  • InChiKey: QASMAIMCCKMUDY-LBPRGKRZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0761 0.2217 0.2217
Echinococcus granulosus transmembrane protease serine 3 0.0111 0.0264 0.0256
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0055 0.0048
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Echinococcus granulosus cathepsin b 0.3349 1 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0279 0.0768 0.0761
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0905 0.2652 0.6375
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Brugia malayi cathepsin Z-like cysteine proteinase 0.0335 0.0938 0.0931
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0335 0.0938 0.0938
Entamoeba histolytica cysteine proteinase, putative 0.0769 0.2242 0.5387
Giardia lamblia Cathepsin L-like protease 0.0335 0.0938 0.2491
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0335 0.0938 0.2242
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0279 0.0768 0.0761
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0761 0.2217 0.2211
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0025 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0273 0.075 0.0743
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1406 0.4156 1
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0025 0.0017
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0055 0.0048
Plasmodium falciparum centrin-1 0.0148 0.0375 0.0886
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Brugia malayi beta-lactamase 0.0036 0.0037 0.0029
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0774 0.0767
Brugia malayi Papain family cysteine protease containing protein 0.0769 0.2242 0.2236
Toxoplasma gondii microneme protein MIC17A 0.003 0.0018 0.0018
Brugia malayi Thioredoxin family protein 0.0173 0.045 0.0443
Loa Loa (eye worm) hypothetical protein 0.2525 0.7522 0.752
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0037 0.0037
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0111 0.0264 0.0256
Trypanosoma brucei hypothetical protein, conserved 0.0148 0.0375 0.0614
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0025 0.0041
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0055 0.0048
Onchocerca volvulus Glycogen phosphorylase homolog 0.0112 0.0266 0.0432
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0335 0.0938 0.2242
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0335 0.0938 0.0938
Trichomonas vaginalis calmodulin, putative 0.0148 0.0375 0.0886
Echinococcus multilocularis cathepsin L 0.0335 0.0938 0.0931
Echinococcus multilocularis gamma secretase subunit aph 1 0.026 0.071 0.0703
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0077 0.016 0.0366
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0046 0.0092
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0264
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0947 0.2778 0.2772
Toxoplasma gondii cathepsin B 0.1267 0.374 0.6231
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0151 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0048
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0342 0.0342
Loa Loa (eye worm) calpain D 0.0279 0.0768 0.0761
Brugia malayi Cathepsin L-like precursor 0.1406 0.4156 0.4151
Trichomonas vaginalis calcineurin B subunit, putative 0.0151 0.0382 0.0903
Onchocerca volvulus 0.003 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Toxoplasma gondii proteasome subunit beta type 2, putative 0.005 0.0078 0.0118
Schistosoma mansoni hypothetical protein 0.0176 0.0458 0.0458
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0335 0.0938 0.0931
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0031 0.0022 0.0023
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0279 0.0768 0.0761
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0055 0.0055
Brugia malayi Cathepsin L-like precursor 0.1406 0.4156 0.4151
Toxoplasma gondii centrin, putative 0.0148 0.0375 0.0614
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3349 1 1
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Onchocerca volvulus 0.0041 0.0052 0.0074
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0774 0.0767
Echinococcus multilocularis glycogen phosphorylase 0.0112 0.0266 0.0259
Trypanosoma cruzi cysteine peptidase, putative 0.0769 0.2242 0.2236
Schistosoma mansoni neuronal calcium sensor 0.0148 0.0375 0.0375
Toxoplasma gondii peptidase family M13 protein 0.0095 0.0215 0.0347
Leishmania major oligopeptidase b 0.0844 0.2467 0.4105
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.005 0.0078 0.0071
Entamoeba histolytica cysteine protease, putative 0.0335 0.0938 0.2242
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Trichomonas vaginalis set domain proteins, putative 0.0759 0.221 0.531
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.0768 0.1833
Leishmania major hypothetical protein, conserved 0.0046 0.0067 0.0099
Echinococcus granulosus glycogen phosphorylase 0.0112 0.0266 0.0259
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0025 0.0041
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0844 0.2467 0.4105
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0025 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.075 0.1791
Onchocerca volvulus Dual oxidase homolog 0.0281 0.0774 0.1279
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Schistosoma mansoni cpg binding protein 0.003 0.002 0.002
Entamoeba histolytica cysteine protease, putative 0.0335 0.0938 0.2242
Plasmodium vivax hypothetical protein, conserved 0.0273 0.075 0.1791
Trypanosoma cruzi Aph-1 protein, putative 0.0101 0.0233 0.0226
Trichomonas vaginalis calmodulin, putative 0.0148 0.0375 0.0886
Trypanosoma brucei Calpain-like protein 2 0.0279 0.0768 0.1269
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0774 0.0767
Plasmodium falciparum plasmepsin VIII, putative 0.0031 0.0022 0.0034
Schistosoma mansoni calmodulin 0.0148 0.0375 0.0375
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0048 0.0075 0.0097
Echinococcus multilocularis cpg binding protein 0.0032 0.0025 0.0018
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0046 0.0041
Schistosoma mansoni cathepsin D (A01 family) 0.0127 0.031 0.031
Leishmania major centrin, putative 0.0148 0.0375 0.0614
Trypanosoma cruzi kinesin, putative 0.0668 0.1939 0.1933
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Schistosoma mansoni reticulocalbin 0.0148 0.0375 0.0375
Onchocerca volvulus 0.1406 0.4156 0.6924
Loa Loa (eye worm) hypothetical protein 0.0335 0.0938 0.0931
Brugia malayi Cathepsin L-like precursor 0.0434 0.1234 0.1227
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0133
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0055 0.0048
Giardia lamblia Cathepsin L precursor 0.0335 0.0938 0.2491
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Entamoeba histolytica grainin, putative 0.0151 0.0382 0.0903
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0769 0.2242 0.373
Echinococcus multilocularis glycogen phosphorylase 0.0112 0.0266 0.0259
Onchocerca volvulus 0.0111 0.0264 0.0427
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0029
Onchocerca volvulus 0.003 0.0018 0.0018
Giardia lamblia Hypothetical protein 0.0335 0.0938 0.2491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Echinococcus granulosus caspase 2 0.0093 0.0207 0.02
Brugia malayi Blistered cuticle protein 3 0.0281 0.0774 0.0767
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0938 0.2242
Echinococcus multilocularis Glycosyl transferase, family 35 0.0112 0.0266 0.0259
Toxoplasma gondii hypothetical protein 0.0279 0.0768 0.1269
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0026 0.0008 0.000000029426
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Mycobacterium ulcerans hypothetical protein 0.0111 0.0264 0.0979
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0124 0.0301 0.0294
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0041 0.0052 0.0107
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Onchocerca volvulus 0.0047 0.0071 0.0105
Onchocerca volvulus 0.0036 0.0037 0.0048
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0164 0.0422 0.1109
Mycobacterium ulcerans hypothetical protein 0.0173 0.045 0.1741
Onchocerca volvulus 0.0111 0.0264 0.0427
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0075 0.0162
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0093 0.0207 0.02
Brugia malayi proteasome subunit beta type 1 0.0077 0.016 0.0152
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0011
Giardia lamblia Cathepsin B precursor 0.0335 0.0938 0.2491
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0947 0.2778 0.4624
Trichomonas vaginalis conserved hypothetical protein 0.0335 0.0938 0.2242
Leishmania major cathepsin L-like protease 0.1406 0.4156 0.6924
Plasmodium falciparum proteasome subunit beta type-5 0.0164 0.0422 0.0998
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0844 0.2467 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0048
Onchocerca volvulus Prolyl endopeptidase homolog 0.2018 0.5998 1
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Echinococcus granulosus cathepsin L cysteine protease 0.0769 0.2242 0.2236
Schistosoma mansoni notch 0.0026 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0054 0.0091 0.0091
Toxoplasma gondii ABC1 family protein 0.0036 0.0037 0.0049
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0055 0.0048
Plasmodium falciparum proteasome subunit beta type-2, putative 0.005 0.0078 0.017
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0026 0.0008 0.0008
Toxoplasma gondii microneme protein, putative 0.003 0.0018 0.0018
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Giardia lamblia Serine peptidase, putative 0.0041 0.0052 0.0119
Brugia malayi Cytochrome P450 family protein 0.0057 0.0101 0.0093
Schistosoma mansoni hemoglobinase (C13 family) 0.0905 0.2652 0.2652
Brugia malayi Cathepsin L-like precursor 0.1406 0.4156 0.4151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.2242 0.5387
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0844 0.2468 0.2463
Loa Loa (eye worm) hypothetical protein 0.3349 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0342 0.0342
Echinococcus multilocularis calbindin 32 0.0151 0.0382 0.0375
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0041 0.0052 0.0107
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0055 0.0048
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0037 0.0029
Mycobacterium tuberculosis Conserved protein 0.0036 0.0037 0.0023
Loa Loa (eye worm) hypothetical protein 0.0111 0.0264 0.0256
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Entamoeba histolytica cysteine proteinase, putative 0.0769 0.2242 0.5387
Giardia lamblia Cathepsin B precursor 0.0335 0.0938 0.2491
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0605 0.1748 0.1741
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0077 0.016 0.0254
Plasmodium falciparum serine repeat antigen 4 0.0335 0.0938 0.2242
Schistosoma mansoni peroxidasin 0.0281 0.0774 0.0774
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0041 0.0052 0.0052
Toxoplasma gondii aspartyl protease ASP3 0.0113 0.0269 0.0436
Echinococcus granulosus cathepsin L cysteine proteinase 0.1406 0.4156 0.4151
Onchocerca volvulus Peroxidase homolog 0.0281 0.0774 0.1279
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0029
Echinococcus granulosus calumenin 0.0151 0.0382 0.0375
Loa Loa (eye worm) cathepsin B 0.1267 0.374 0.3736
Entamoeba histolytica cysteine proteinase, putative 0.0769 0.2242 0.5387
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.0301 0.0708
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0033 0.0043
Trypanosoma brucei kinesin, putative 0.0668 0.1939 0.3224
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0055 0.0048
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0335 0.0938 0.2242
Entamoeba histolytica GPI-anchor transamidase, putative 0.021 0.0561 0.1334
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0138
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0335 0.0938 0.0938
Toxoplasma gondii preprocathepsin c precursor, putative 0.0335 0.0938 0.1552
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0055 0.0114
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0037 0.0023
Plasmodium falciparum calpain 0.0279 0.0768 0.1833
Brugia malayi calpain family protein 1 0.2525 0.7522 0.752
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.033 0.0593
Toxoplasma gondii kringle domain-containing protein 0.0046 0.0067 0.0099
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0031 0.0022 0.0023
Loa Loa (eye worm) proteasome subunit beta type 2 0.005 0.0078 0.0071
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0018 0.0018
Schistosoma mansoni hemoglobinase (C13 family) 0.0905 0.2652 0.2652
Schistosoma mansoni hypothetical protein 0.0148 0.0375 0.0375
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0774 0.0767
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0905 0.2652 0.6375
Brugia malayi Cathepsin L-like precursor 0.1406 0.4156 0.4151
Onchocerca volvulus 0.0281 0.0774 0.1279
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Echinococcus multilocularis acylamino acid releasing enzyme 0.0273 0.075 0.0743
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2673 0.7968 0.7968
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0055 0.0048
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0011
Onchocerca volvulus Chorion peroxidase homolog 0.0281 0.0774 0.1279
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0055 0.0055
Trypanosoma brucei protein I/6 0.0148 0.0375 0.0614
Loa Loa (eye worm) hypothetical protein 0.0105 0.0245 0.0238
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0031 0.0022 0.0014
Schistosoma mansoni hypothetical protein 0.0046 0.0067 0.0067
Leishmania major centrin, putative 0.0148 0.0375 0.0614
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0101 0.0093
Leishmania major protein kinase, putative 0.0148 0.0375 0.0614
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0025 0.0029
Trypanosoma brucei centrin-3 0.0152 0.0386 0.0632
Entamoeba histolytica cysteine proteinase 2 0.0769 0.2242 0.5387
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0148 0.0375 0.0368
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0025 0.0017
Toxoplasma gondii prolyl endopeptidase 0.2018 0.5998 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0335 0.0938 0.0931
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0972 0.2851 0.6855
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0055 0.0055
Leishmania major calpain family cysteine protease-like protein 0.0279 0.0768 0.1269
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0055 0.0048
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0048 0.0075 0.0205
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0011
Loa Loa (eye worm) hypothetical protein 0.2018 0.5998 0.5995
Entamoeba histolytica hypothetical protein 0.0042 0.0055 0.0114
Schistosoma mansoni septate junction protein 0.0026 0.0008 0.0008
Schistosoma mansoni neuronal calcium sensor 0.0148 0.0375 0.0375
Onchocerca volvulus Cathepsin L homolog 0.1406 0.4156 0.6924
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0004 0.0004
Trichomonas vaginalis calmodulin, putative 0.0148 0.0375 0.0886
Schistosoma mansoni glycogen phosphorylase 0.0048 0.0075 0.0075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Loa Loa (eye worm) calpain 5 0.0668 0.1939 0.1933
Brugia malayi Peroxidasin 0.0281 0.0774 0.0767
Brugia malayi hypothetical protein 0.0042 0.0055 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.0972 0.2851 0.6855
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0025 0.0017
Brugia malayi NAD-dependent deacetylase SIRT1 0.0137 0.0341 0.0334
Echinococcus multilocularis survival motor neuron protein 1 0.0264 0.0723 0.0716
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1406 0.4156 0.4151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Loa Loa (eye worm) hypothetical protein 0.0434 0.1234 0.1227
Trichomonas vaginalis calmodulin, putative 0.0148 0.0375 0.0886
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0011
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0148 0.0375 0.0368
Brugia malayi EF hand family protein 0.0148 0.0375 0.0368
Brugia malayi Eukaryotic aspartyl protease family protein 0.0031 0.0022 0.0014
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0124 0.0301 0.049
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0164 0.0422 0.0998
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0031 0.0022 0.0034
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Echinococcus granulosus Mastin 0.0111 0.0264 0.0256
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0273 0.075 0.1791
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0112 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Onchocerca volvulus 0.0111 0.0264 0.0427
Leishmania major cathepsin L-like protease 0.1406 0.4156 0.6924
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0844 0.2467 0.2461
Plasmodium vivax serine-repeat antigen (SERA) 0.0335 0.0938 0.2242
Onchocerca volvulus 0.0036 0.0037 0.0048
Echinococcus granulosus calpain A 0.0947 0.2778 0.2772
Onchocerca volvulus Deterin homolog 0.0176 0.0458 0.0752
Echinococcus multilocularis cathepsin L cysteine protease 0.1406 0.4156 0.4151
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0033 0.0026
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0018
Brugia malayi hypothetical protein 0.0222 0.0598 0.0591
Onchocerca volvulus Cell death protein 3 homolog 0.0093 0.0207 0.0333
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1406 0.4156 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0769 0.2242 0.2242
Brugia malayi cathepsin L precursor 0.0335 0.0938 0.0931
Echinococcus multilocularis apoptotic protease activating factor 1 0.0093 0.0207 0.02
Trichomonas vaginalis calmodulin, putative 0.0151 0.0382 0.0903
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0774 0.0767
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0114
Schistosoma mansoni hypothetical protein 0.0025 0.0004 0.0004
Loa Loa (eye worm) glycogen phosphorylase 0.0112 0.0266 0.0259
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.021 0.0561 0.1334
Brugia malayi hypothetical protein 0.0042 0.0055 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0938 0.2242
Mycobacterium leprae Conserved hypothetical protein 0.0173 0.045 0.1701
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0279 0.0768 0.1269
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.4624
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0041 0.0052 0.0044
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0434 0.1234 0.1227
Onchocerca volvulus 0.003 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0138
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0148 0.0375 0.0368
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Loa Loa (eye worm) hypothetical protein 0.0335 0.0938 0.0931
Brugia malayi Cathepsin L-like precursor 0.1406 0.4156 0.4151
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0018
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Echinococcus granulosus tissue type plasminogen activator 0.0046 0.0067 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Giardia lamblia Alanyl dipeptidyl peptidase 0.0273 0.075 0.199
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0037 0.0023
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0605 0.1748 0.1748
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0037 0.007
Plasmodium vivax aspartyl proteinase, putative 0.0031 0.0022 0.0034
Onchocerca volvulus 0.0055 0.0093 0.0143
Loa Loa (eye worm) hypothetical protein 0.0095 0.0215 0.0208
Giardia lamblia Cathepsin L precursor 0.0335 0.0938 0.2491
Loa Loa (eye worm) blistered cuticle protein 3 0.0281 0.0774 0.0767
Schistosoma mansoni notch 0.0026 0.0008 0.0008
Plasmodium vivax vivapain-3 0.0769 0.2242 0.5387
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0148 0.0375 0.0886
Echinococcus granulosus cysteine protease 0.0769 0.2242 0.2236
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0077 0.016 0.0254
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0335 0.0938 0.0938
Echinococcus multilocularis peroxidasin 0.0281 0.0774 0.0767
Trypanosoma brucei Calpain-like protein 1.2 0.0279 0.0768 0.1269
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0335 0.0938 0.2491
Brugia malayi programmed cell death protein 6 0.0148 0.0375 0.0368
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0844 0.2468 0.2468
Plasmodium falciparum plasmepsin V 0.0031 0.0022 0.0034
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0844 0.2467 0.2461
Echinococcus granulosus programmed cell death protein 0.0152 0.0386 0.0379
Brugia malayi PXA domain containing protein 0.0042 0.0055 0.0048
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0067 0.0059
Brugia malayi cathepsin F-like cysteine proteinase 0.0434 0.1234 0.1227
Loa Loa (eye worm) programmed cell death protein 6 0.0151 0.0382 0.0375
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0264
Trypanosoma cruzi cysteine peptidase, putative 0.1508 0.4465 0.4461
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0014
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0667 0.1933 0.1927
Echinococcus granulosus Glycosyl transferase family 35 0.0112 0.0266 0.0259
Trypanosoma cruzi cysteine peptidase, putative 0.1508 0.4465 0.4461
Entamoeba histolytica grainin 2 0.0152 0.0386 0.0912
Entamoeba histolytica calpain large subunit domain III containing protein 0.0668 0.1939 0.4656
Trypanosoma cruzi centrin-3 0.0152 0.0386 0.0379
Echinococcus granulosus tumor protein p63 0.0373 0.1052 0.1045
Onchocerca volvulus 0.0281 0.0774 0.1279
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0605 0.1748 0.1741
Plasmodium vivax GPI-anchor transamidase, putative 0.021 0.0561 0.1334
Loa Loa (eye worm) hypothetical protein 0.0137 0.0341 0.0334
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0335 0.0938 0.2242
Loa Loa (eye worm) hypothetical protein 0.0111 0.0264 0.0256
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0273 0.075 0.1791
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.1578 0.4673 0.4669
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0055 0.0055
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0273 0.075 0.075
Trypanosoma brucei calpain, putative 0.0279 0.0768 0.1269
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0111 0.0264 0.0256
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0077 0.016 0.0152
Brugia malayi aspartic protease BmAsp-1, identical 0.0031 0.0022 0.0014
Brugia malayi prolyl oligopeptidase family protein 0.2018 0.5998 0.5995
Toxoplasma gondii hypothetical protein 0.003 0.0018 0.0018
Echinococcus multilocularis EF hand domain containing family member A2 0.0148 0.0375 0.0368
Schistosoma mansoni neuronal calcium sensor 0.0148 0.0375 0.0375
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0834 0.2436 0.2431
Plasmodium falciparum cysteine repeat modular protein 1 0.0046 0.0067 0.0143
Trypanosoma cruzi oligopeptidase b 0.0844 0.2467 0.2461
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Giardia lamblia Sirtuin type 2 0.0032 0.0025 0.0046
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0055 0.0048
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0294 0.0287
Echinococcus multilocularis neuronal calcium sensor 0.0148 0.0375 0.0368
Echinococcus multilocularis GPI anchor transamidase 0.021 0.0561 0.0554
Plasmodium falciparum serine repeat antigen 3 0.0335 0.0938 0.2242
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0279 0.0768 0.1833
Plasmodium vivax proteasome subunit beta type-5, putative 0.0164 0.0422 0.0998
Schistosoma mansoni hypothetical protein 0.0093 0.0207 0.0207
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.033 0.0323
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0301 0.0301
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0335 0.0938 0.2242
Loa Loa (eye worm) fibroinase 0.1406 0.4156 0.4151
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0335 0.0938 0.0938
Trypanosoma brucei I/6 autoantigen 0.0148 0.0375 0.0614
Giardia lamblia Transglutaminase/protease, putative 0.0173 0.045 0.1185
Echinococcus granulosus gamma secretase subunit aph 1 0.026 0.071 0.0703
Loa Loa (eye worm) beta-lactamase 0.0036 0.0037 0.0029
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0044
Trichomonas vaginalis calpain, putative 0.0279 0.0768 0.1833
Trypanosoma brucei prolyl oligopeptidase, putative 0.0844 0.2467 0.4105
Brugia malayi aspartic protease BmAsp-2, identical 0.0031 0.0022 0.0014
Plasmodium falciparum GPI-anchor transamidase, putative 0.021 0.0561 0.1334
Giardia lamblia GPI-anchor transamidase, putative 0.021 0.0561 0.1482
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2778 0.2772
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Entamoeba histolytica cysteine proteinase, putative 0.1406 0.4156 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0033 0.0034
Echinococcus granulosus EF hand domain containing family member A2 0.0151 0.0382 0.0375
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0164 0.0422 0.0422
Echinococcus granulosus centrin 2 0.0148 0.0375 0.0368
Mycobacterium ulcerans putative transglutaminase-like protein 0.0173 0.045 0.1741
Loa Loa (eye worm) hypothetical protein 0.0148 0.0375 0.0368
Schistosoma mansoni ap endonuclease 0.0039 0.0046 0.0046
Schistosoma mansoni centrin-related 0.0148 0.0375 0.0375
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0046 0.0092
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0335 0.0938 0.2242
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0164 0.0422 0.0414
Echinococcus granulosus Transglutaminase 0.0173 0.045 0.0443
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0025 0.0029
Schistosoma mansoni cathepsin F (C01 family) 0.0972 0.2851 0.2851
Schistosoma mansoni calmodulin 0.0148 0.0375 0.0375
Leishmania major cathepsin L-like protease 0.1508 0.4465 0.744
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0018
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0905 0.2652 0.2652
Plasmodium falciparum serine repeat antigen 5 0.0335 0.0938 0.2242
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0041 0.0052 0.0044
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.033 0.033
Schistosoma mansoni gamma-secretase subunit aph-1 0.026 0.071 0.071
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0025 0.0017
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0055 0.0048
Trypanosoma brucei proteasome beta 6 subunit 0.0077 0.016 0.0254
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0342 0.0342
Toxoplasma gondii calcium-dependent protein kinase 0.0151 0.0382 0.0626
Toxoplasma gondii aspartyl protease 0.0031 0.0022 0.0023
Trichomonas vaginalis glycogen phosphorylase, putative 0.0112 0.0266 0.0624
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0342 0.0335
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0273 0.075 0.1791
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0148 0.0375 0.0614
Loa Loa (eye worm) hypothetical protein 0.0046 0.0067 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0335 0.0938 0.2242
Entamoeba histolytica calcium-binding protein, putative 0.0148 0.0375 0.0886
Giardia lamblia Cysteine protease 0.0335 0.0938 0.2491
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0164 0.0422 0.077
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0011
Leishmania major sir2-family protein-like protein 0.0032 0.0025 0.0029
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Loa Loa (eye worm) proteasome subunit beta type 1 0.0077 0.016 0.0152
Brugia malayi Cathepsin L-like precursor 0.1406 0.4156 0.4151
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0769 0.2242 0.2242
Schistosoma mansoni hypothetical protein 0.0025 0.0004 0.0004
Chlamydia trachomatis glycogen phosphorylase 0.0112 0.0266 0.5
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0769 0.2242 0.2242
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0114
Loa Loa (eye worm) hypothetical protein 0.0111 0.0264 0.0256
Loa Loa (eye worm) hypothetical protein 0.0111 0.0264 0.0256
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0335 0.0938 0.2242
Giardia lamblia Cysteine protease 0.0335 0.0938 0.2491
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Onchocerca volvulus 0.0281 0.0774 0.1279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Mycobacterium ulcerans proteasome PrcB 0.0164 0.0422 0.1625
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.2772
Entamoeba histolytica calmodulin, putative 0.0148 0.0375 0.0886
Onchocerca volvulus 0.0036 0.0037 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0052 0.0107
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0033 0.0026
Schistosoma mansoni cathepsin D (A01 family) 0.0127 0.031 0.031
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.1406 0.4156 0.4151
Loa Loa (eye worm) aspartyl protease 6 0.0031 0.0022 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Brugia malayi prolyl oligopeptidase family protein 0.0844 0.2468 0.2463
Plasmodium vivax unspecified product 0.0434 0.1234 0.2956
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0041 0.0052 0.0044
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0037 0.0029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3349 1 1
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1406 0.4156 0.4151
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0279 0.0768 0.0761
Leishmania major programmed cell death 6 protein-like protein 0.0148 0.0375 0.0614
Trypanosoma brucei centrin, putative 0.0148 0.0375 0.0614
Giardia lamblia Alanyl dipeptidyl peptidase 0.0273 0.075 0.199
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Trypanosoma cruzi cysteine proteinase, putative 0.0769 0.2242 0.2236
Leishmania major proteasome beta 5 subunit, putative 0.0164 0.0422 0.0691
Brugia malayi Pepsin A precursor 0.0031 0.0022 0.0014
Mycobacterium tuberculosis Long conserved protein 0.0173 0.045 0.0825
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0025 0.0041
Plasmodium falciparum serine repeat antigen 9 0.0335 0.0938 0.2242
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0055 0.0048
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0335 0.0938 0.0938
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Echinococcus multilocularis endothelin converting enzyme 1 0.0095 0.0215 0.0208
Brugia malayi calpain 5 0.0279 0.0768 0.0761
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0114
Brugia malayi Kringle domain containing protein 0.0046 0.0067 0.0059
Loa Loa (eye worm) EF hand family protein 0.0148 0.0375 0.0368
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0341 0.0804
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2778 0.4624
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.005 0.0078 0.0071
Brugia malayi prolyl oligopeptidase family protein 0.0273 0.075 0.0743
Brugia malayi cathepsin L-like precursor 0.0972 0.2851 0.2846
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0148 0.0375 0.0368
Onchocerca volvulus 0.0148 0.0375 0.0613
Brugia malayi beta-lactamase family protein 0.0036 0.0037 0.0029
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0046 0.0064
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2673 0.7968 0.7968
Toxoplasma gondii microneme protein MIC4 0.003 0.0018 0.0018
Mycobacterium ulcerans lipase LipD 0.0036 0.0037 0.0049
Brugia malayi fibroinase precursor 0.0335 0.0938 0.0931
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0273 0.075 0.124
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0091 0.0084
Brugia malayi calpain 5 0.0668 0.1939 0.1933
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0938 0.2242
Onchocerca volvulus 0.1406 0.4156 0.6924
Onchocerca volvulus Peroxidasin homolog 0.0281 0.0774 0.1279
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0938 0.2242
Brugia malayi Papain family cysteine protease containing protein 0.0335 0.0938 0.0931
Echinococcus granulosus calmodulin 0.0148 0.0375 0.0368
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2778 0.4624
Brugia malayi Serine protease Z688.6 precursor 0.0041 0.0052 0.0044
Mycobacterium ulcerans transglutaminase family protein 0.0173 0.045 0.1741
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Echinococcus multilocularis cathepsin L cysteine protease 0.1406 0.4156 0.4151
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0905 0.2652 0.6375
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0111 0.0264 0.0256
Brugia malayi Trypsin family protein 0.0111 0.0264 0.0256
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0137 0.0341 0.0334
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0055 0.0048
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0138
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Giardia lamblia Cathepsin B precursor 0.0335 0.0938 0.2491
Trypanosoma cruzi I/6 autoantigen, putative 0.0148 0.0375 0.0368
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0279 0.0768 0.1833
Loa Loa (eye worm) transcriptional regulator 0.0124 0.0301 0.0294
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0335 0.0938 0.2491
Toxoplasma gondii microneme protein MIC17C 0.003 0.0018 0.0018
Echinococcus granulosus Dipeptidyl peptidase 9 0.0605 0.1748 0.1741
Schistosoma mansoni notch 0.0026 0.0008 0.0008
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0844 0.2468 0.2463
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0218 0.0352
Brugia malayi calpain 7 0.0947 0.2778 0.2772
Brugia malayi proteasome subunit beta type 2 0.005 0.0078 0.0071
Loa Loa (eye worm) hypothetical protein 0.0148 0.0375 0.0368
Echinococcus multilocularis programmed cell death protein 0.0152 0.0386 0.0379
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0264
Brugia malayi hypothetical protein 0.0167 0.0431 0.0424
Brugia malayi hypothetical protein 0.0111 0.0264 0.0256
Plasmodium falciparum plasmepsin VII 0.0031 0.0022 0.0034
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2673 0.7968 0.7966
Mycobacterium tuberculosis Probable peptidase 0.0844 0.2467 0.474
Trypanosoma brucei antigen, putative 0.0947 0.2778 0.4624
Onchocerca volvulus 0.003 0.0018 0.0018
Schistosoma mansoni notch 0.0026 0.0008 0.0008
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2018 0.5998 1
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0905 0.2652 0.6375
Schistosoma mansoni slit 0.0026 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0046 0.5
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0774 0.0767
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2778 0.4624
Toxoplasma gondii cathepsin CPC2 0.0335 0.0938 0.1552
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0055 0.0055
Schistosoma mansoni cpg binding protein 0.0032 0.0025 0.0025
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0055 0.0048
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0033 0.0026
Onchocerca volvulus 0.0031 0.0022 0.0023
Schistosoma mansoni cathepsin B (C01 family) 0.0335 0.0938 0.0938
Trypanosoma cruzi hypothetical protein, conserved 0.0273 0.075 0.0743
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0138
Loa Loa (eye worm) hypothetical protein 0.0095 0.0215 0.0208
Loa Loa (eye worm) cysteine protease 0.1406 0.4156 0.4151
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1745 0.5177 1
Leishmania major cathepsin L-like protease 0.1406 0.4156 0.6924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Giardia lamblia Cathepsin L precursor 0.0335 0.0938 0.2491
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0151 0.0382 0.0375
Brugia malayi cathepsin L-like cysteine proteinase 0.0335 0.0938 0.0931
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0335 0.0938 0.2242
Trypanosoma cruzi calmodulin, putative 0.0148 0.0375 0.0368
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0164 0.0422 0.0998
Echinococcus granulosus survival motor neuron protein 1 0.0264 0.0723 0.0716
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0055 0.0055
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.0342 0.0335
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0342 0.0335
Trichomonas vaginalis calmodulin, putative 0.0148 0.0375 0.0886
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0078 0.017
Brugia malayi hypothetical protein 0.0031 0.0022 0.0014
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1075 0.316 0.3155
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0029
Brugia malayi Trypsin family protein 0.0111 0.0264 0.0256
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0077 0.016 0.0366
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0774 0.0767
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.4624
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0055 0.0055
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0434 0.1234 0.1227
Entamoeba histolytica glycogenphosphorylase, putative 0.0048 0.0075 0.0162
Schistosoma mansoni survival motor neuron protein 0.0054 0.0091 0.0091
Trypanosoma brucei Calpain-like protein CALP1.3 0.0279 0.0768 0.1269
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0114
Toxoplasma gondii EFHC1, putative 0.0148 0.0375 0.0614
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0055 0.0048
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2525 0.7522 0.7522
Trichomonas vaginalis myosin light chain 1, putative 0.0148 0.0375 0.0886
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0055 0.0048
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0124 0.0301 0.0708
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0095 0.0215 0.0215
Schistosoma mansoni calpain-2 (C02 family) 0.0279 0.0768 0.0768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0046 0.0038
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0037 0.0029
Mycobacterium tuberculosis Conserved hypothetical protein 0.0173 0.045 0.0825
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0124 0.0301 0.0294
Giardia lamblia Glycogen phosphorylase 0.0112 0.0266 0.0693
Brugia malayi gamma-secretase subunit aph-1 0.026 0.071 0.0703
Brugia malayi Pre-SET motif family protein 0.0096 0.0218 0.0211
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0025 0.0029
Trypanosoma cruzi centrin, putative 0.0152 0.0386 0.0379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0769 0.2242 0.373
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0844 0.2468 0.4107
Schistosoma mansoni hypothetical protein 0.0025 0.0004 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0294 0.0287
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0148 0.0375 0.0886
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Plasmodium vivax SET domain protein, putative 0.0096 0.0218 0.0508
Toxoplasma gondii cathepsin CPC1 0.0335 0.0938 0.1552
Trypanosoma brucei prolyl endopeptidase 0.2018 0.5998 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0037 0.0023
Echinococcus multilocularis tissue type plasminogen activator 0.0046 0.0067 0.0059
Schistosoma mansoni hypothetical protein 0.0025 0.0004 0.0004
Echinococcus multilocularis Transglutaminase 0.0173 0.045 0.0443
Loa Loa (eye worm) hypothetical protein 0.0222 0.0598 0.0591
Schistosoma mansoni calpain C (C02 family) 0.0947 0.2778 0.2778
Brugia malayi Trypsin family protein 0.0111 0.0264 0.0256
Entamoeba histolytica hypothetical protein 0.0042 0.0055 0.0114
Trypanosoma cruzi cruzipain precursor, putative 0.0434 0.1234 0.1227
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0164 0.0422 0.1584
Schistosoma mansoni cathepsin F (C01 family) 0.1406 0.4156 0.4156
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0029
Echinococcus granulosus cathepsin l1 0.0972 0.2851 0.2846
Plasmodium vivax vivapain-1 0.0769 0.2242 0.5387
Trypanosoma brucei hypothetical protein 0.0279 0.0768 0.1269
Plasmodium vivax aspartyl proteinase, putative 0.0031 0.0022 0.0034
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0335 0.0938 0.2242
Brugia malayi Papain family cysteine protease containing protein 0.0769 0.2242 0.2236
Trypanosoma cruzi cysteine peptidase, putative 0.0434 0.1234 0.1227
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Schistosoma mansoni cathepsin s 0.0434 0.1234 0.1234
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0044
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0041 0.0052 0.0107
Trichomonas vaginalis hypothetical protein 0.0279 0.0768 0.1833
Entamoeba histolytica glycogen phosphorylase, putative 0.0048 0.0075 0.0162
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Brugia malayi beta-lactamase family protein 0.0036 0.0037 0.0029
Leishmania major proteasome beta 2 subunit, putative 0.005 0.0078 0.0118
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0037 0.007
Brugia malayi Peptidase C13 family protein 0.0905 0.2652 0.2646
Plasmodium vivax serine-repeat antigen (SERA) 0.0335 0.0938 0.2242
Plasmodium falciparum serine repeat antigen 8 0.0335 0.0938 0.2242
Echinococcus multilocularis cathepsin b 0.3349 1 1
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0046 0.0067 0.0143
Giardia lamblia Hypothetical protein 0.0124 0.0301 0.0787
Echinococcus granulosus prolyl endopeptidase 0.2018 0.5998 0.5995
Plasmodium vivax plasmepsin V, putative 0.0031 0.0022 0.0034
Echinococcus granulosus cpg binding protein 0.0032 0.0025 0.0018
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0148 0.0375 0.0614
Schistosoma mansoni calpain-7 (C02 family) 0.095 0.2787 0.2787
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0046 0.0092
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0025 0.0029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0133 0.0133
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0335 0.0938 0.2242
Echinococcus granulosus calpain A 0.2676 0.7975 0.7974
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Echinococcus multilocularis calpain family protein 1, d 0.1857 0.5512 0.5509
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0111 0.0264 0.0256
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0335 0.0938 0.2242
Leishmania major cathepsin L-like protease 0.1508 0.4465 0.744
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0025 0.0017
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0046 0.0038
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.021 0.0561 0.0924
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0093 0.0093
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0335 0.0938 0.2242
Trichomonas vaginalis calcium binding protein, putative 0.0148 0.0375 0.0886
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0341 0.0804
Leishmania major cytochrome p450-like protein 0.0035 0.0033 0.0043
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0037 0.007
Trichomonas vaginalis calmodulin, putative 0.0148 0.0375 0.0886
Loa Loa (eye worm) hypothetical protein 0.0111 0.0264 0.0256
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0055 0.0055
Brugia malayi MH2 domain containing protein 0.0121 0.0294 0.0287
Onchocerca volvulus 0.0176 0.0458 0.0752
Schistosoma mansoni glycogen phosphorylase 0.0112 0.0266 0.0266
Entamoeba histolytica cysteine protease, putative 0.0335 0.0938 0.2242
Brugia malayi hypothetical protein 0.0264 0.0723 0.0716
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0905 0.2652 0.6375
Trichomonas vaginalis centrin, putative 0.0148 0.0375 0.0886
Toxoplasma gondii EF hand domain-containing protein 0.0148 0.0375 0.0614
Plasmodium vivax unspecified product 0.0769 0.2242 0.5387
Giardia lamblia Proteasome subunit beta type 2 0.005 0.0078 0.0189
Entamoeba histolytica protein kinase, putative 0.0668 0.1939 0.4656
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.033 0.0539
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0077 0.016 0.016
Echinococcus granulosus calpain 0.0947 0.2778 0.2772
Entamoeba histolytica cysteine proteinase 1, putative 0.0769 0.2242 0.5387
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0273 0.075 0.124
Loa Loa (eye worm) peptidase C13 family protein 0.0905 0.2652 0.2646
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.0025 0.0046
Loa Loa (eye worm) calpain 0.0947 0.2778 0.2772
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0037 0.007
Toxoplasma gondii proteasome subunit beta type, putative 0.0164 0.0422 0.0691
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0279 0.0768 0.1269
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0133
Giardia lamblia Hypothetical protein 0.0173 0.045 0.1185
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0025 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0335 0.0938 0.2242
Schistosoma mansoni reticulocalbin 0.0151 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0434 0.1234 0.1227
Trypanosoma brucei caltractin, putative 0.0152 0.0386 0.0632
Mycobacterium tuberculosis Conserved protein 0.0036 0.0037 0.0023
Echinococcus granulosus inhibitor of apoptosis protein 0.0176 0.0458 0.0451
Brugia malayi Trypsin-like protease protein 5 0.0111 0.0264 0.0256
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0046 0.0092
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0025 0.0041
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0018 0.0018
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0218 0.0211
Schistosoma mansoni hypothetical protein 0.0111 0.0264 0.0264
Onchocerca volvulus 0.1406 0.4156 0.6924
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0037 0.0029
Loa Loa (eye worm) prolyl oligopeptidase 0.0844 0.2468 0.2463
Leishmania major hypothetical protein, conserved 0.0151 0.0382 0.0626
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.2772
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0335 0.0938 0.0931
Plasmodium falciparum plasmepsin IX 0.0113 0.0269 0.063
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2018 0.5998 0.5998
Trypanosoma cruzi cysteine peptidase, putative 0.1508 0.4465 0.4461
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0037 0.0029
Echinococcus multilocularis cysteine protease 0.1406 0.4156 0.4151
Loa Loa (eye worm) hypothetical protein 0.0972 0.2851 0.2846
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0844 0.2467 0.4105
Echinococcus multilocularis calcium uptake protein 1 0.0151 0.0382 0.0375
Trypanosoma brucei cysteine peptidase, putative 0.0279 0.0768 0.1269
Schistosoma mansoni hypothetical protein 0.0025 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0029
Echinococcus multilocularis cathepsin b 0.3349 1 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.033 0.0323
Loa Loa (eye worm) hypothetical protein 0.1857 0.5512 0.5509
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0335 0.0938 0.2242
Echinococcus multilocularis Mastin 0.0111 0.0264 0.0256
Brugia malayi hypothetical protein 0.0093 0.0207 0.02
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0048
Plasmodium falciparum plasmepsin X 0.0113 0.0269 0.063
Echinococcus granulosus cathepsin l cysteine peptidase 0.1406 0.4156 0.4151
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0301 0.0301
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0055 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0938 0.2242
Entamoeba histolytica hypothetical protein, conserved 0.0273 0.075 0.1791
Toxoplasma gondii PAN domain-containing protein 0.003 0.0018 0.0018
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0341 0.0804
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0279 0.0768 0.1833
Echinococcus granulosus calcium uptake protein 1 0.0151 0.0382 0.0375
Schistosoma mansoni hypothetical protein 0.0432 0.1227 0.1227
Brugia malayi Cytochrome P450 family protein 0.0035 0.0033 0.0026
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0176 0.0458 0.0451
Brugia malayi calcium-binding protein 0.0148 0.0375 0.0368
Trypanosoma brucei Calpain-like protein 1.1 0.0279 0.0768 0.1269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0037 0.0037
Schistosoma mansoni Mername-AA248 (C02 family) 0.0947 0.2778 0.2778
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0124 0.0301 0.0708
Giardia lamblia Cathepsin B precursor 0.1267 0.374 1
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0008 0.0008
Entamoeba histolytica hypothetical protein, conserved 0.0151 0.0382 0.0903
Trichomonas vaginalis calcineurin B subunit, putative 0.0148 0.0375 0.0886
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.0206 0.0198
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0256
Onchocerca volvulus 0.0111 0.0264 0.0427
Trichomonas vaginalis calmodulin, putative 0.0152 0.0386 0.0912
Echinococcus granulosus apoptotic protease activating factor 1 0.0093 0.0207 0.02
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0335 0.0938 0.0931
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0148 0.0375 0.0368
Brugia malayi Proteasome A-type and B-type family protein 0.0164 0.0422 0.0414
Echinococcus multilocularis calpain A 0.2676 0.7975 0.7974
Entamoeba histolytica glycogen phosphorylase, putative 0.0112 0.0266 0.0624
Trypanosoma brucei oligopeptidase b 0.0844 0.2467 0.4105
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1406 0.4156 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0077 0.016 0.0152
Onchocerca volvulus 0.0096 0.0218 0.0351
Echinococcus multilocularis programmed cell death protein 0.0152 0.0386 0.0379
Trypanosoma brucei calmodulin, putative 0.0148 0.0375 0.0614
Onchocerca volvulus 0.1406 0.4156 0.6924
Toxoplasma gondii peptidase c13 family protein 0.021 0.0561 0.0924
Loa Loa (eye worm) calpain family protein 1 0.1857 0.5512 0.5509
Trypanosoma cruzi cruzipain precursor, putative 0.1508 0.4465 0.4461
Mycobacterium ulcerans zinc metalloprotease 0.0095 0.0215 0.0781
Mycobacterium tuberculosis Hypothetical protein 0.0173 0.045 0.0825
Loa Loa (eye worm) hypothetical protein 0.0176 0.0458 0.0451
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0031 0.0022 0.0014
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0041
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0055 0.0048
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.4624
Loa Loa (eye worm) prolyl oligopeptidase 0.0273 0.075 0.0743
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1267 0.374 0.8999
Trypanosoma brucei mitochondrial calcium uptake 1 0.0148 0.0375 0.0614
Toxoplasma gondii troponin c, isotype gamma, putative 0.0148 0.0375 0.0614
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0335 0.0938 0.2242
Trypanosoma brucei calmodulin, putative 0.0151 0.0382 0.0626
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0176 0.0458 0.0458
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1267 0.374 0.374
Loa Loa (eye worm) hypothetical protein 0.0176 0.0458 0.0451
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0055 0.0048
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0025 0.0041
Onchocerca volvulus 0.003 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Brugia malayi Papain family cysteine protease containing protein 0.0335 0.0938 0.0931
Loa Loa (eye worm) trypsin family protein 0.0111 0.0264 0.0256
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0041 0.0052 0.0044
Trichomonas vaginalis calpain, putative 0.0279 0.0768 0.1833
Leishmania major kinesin, putative 0.0668 0.1939 0.3224
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0029
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0041 0.0052 0.0107
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0133
Echinococcus granulosus calpain 5 0.0947 0.2778 0.2772
Echinococcus granulosus microtubule associated protein 2 0.1491 0.4413 0.4409
Brugia malayi GPI-anchor transamidase 0.021 0.0561 0.0554
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0055 0.0048
Brugia malayi Serine protease Z688.6 precursor 0.0041 0.0052 0.0044
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0335 0.0938 0.0938
Onchocerca volvulus Peroxidase homolog 0.0281 0.0774 0.1279
Echinococcus granulosus calpain 7 C02 family 0.0947 0.2778 0.2772
Trichomonas vaginalis calcium binding protein, putative 0.0152 0.0386 0.0912
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2778 0.2772
Schistosoma mansoni microtubule-associated protein tau 0.1491 0.4413 0.4413
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Schistosoma mansoni notch 0.0026 0.0009 0.0009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0046 0.0085
Onchocerca volvulus 0.003 0.0018 0.0018
Toxoplasma gondii exonuclease III APE 0.0039 0.0046 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0151 0.0382 0.0903
Loa Loa (eye worm) hypothetical protein 0.0047 0.0071 0.0063
Leishmania major calmodulin-like protein 0.0148 0.0375 0.0614
Brugia malayi CXXC zinc finger family protein 0.003 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0011
Trypanosoma brucei Aph-1 protein, putative 0.0101 0.0233 0.0377
Leishmania major phospholipase c-like protein 0.0148 0.0375 0.0614
Echinococcus multilocularis calpain 7 (C02 family) 0.0947 0.2778 0.2772
Onchocerca volvulus 0.003 0.002 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1267 0.374 0.6231
Brugia malayi calpain family protein 1 0.2525 0.7522 0.752
Mycobacterium ulcerans beta-lactamase 0.0036 0.0037 0.0049
Plasmodium falciparum plasmepsin III 0.0031 0.0022 0.0034
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0055 0.0048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.2772
Trichomonas vaginalis esterase, putative 0.0036 0.0037 0.007
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0279 0.0768 0.1833
Giardia lamblia Cathepsin L precursor 0.0335 0.0938 0.2491
Entamoeba histolytica calcium binding family protein 0.0148 0.0375 0.0886
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0041 0.0052 0.0107
Brugia malayi PXA domain containing protein 0.0042 0.0055 0.0048
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0048
Entamoeba histolytica cysteine protease, putative 0.0335 0.0938 0.2242
Echinococcus multilocularis caspase 2 0.0093 0.0207 0.02
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.4624
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0375 0.0886
Onchocerca volvulus 0.1406 0.4156 0.6924
Trypanosoma cruzi calmodulin, putative 0.0148 0.0375 0.0368
Onchocerca volvulus 0.1578 0.4673 0.7788
Giardia lamblia Cathepsin B precursor 0.0335 0.0938 0.2491
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0046 0.0038
Loa Loa (eye worm) hypothetical protein 0.0167 0.0431 0.0424
Brugia malayi Serine carboxypeptidase S28 family protein 0.0041 0.0052 0.0044
Echinococcus granulosus enteropeptidase 0.0111 0.0264 0.0256
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0055 0.0055
Entamoeba histolytica cysteine proteinase, putative 0.1406 0.4156 1
Leishmania major hypothetical protein, conserved 0.0279 0.0768 0.1269
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0055 0.0055
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0218 0.0211
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0078 0.017
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0111 0.0264 0.0256
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0033 0.0026
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0077 0.016 0.0152
Echinococcus granulosus EF hand domain containing family member A2 0.0148 0.0375 0.0368
Echinococcus granulosus acylamino acid releasing enzyme 0.0273 0.075 0.0743
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0141 0.0133
Entamoeba histolytica calmodulin, putative 0.0148 0.0375 0.0886
Leishmania major calcineurin B subunit, putative 0.0148 0.0375 0.0614
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Loa Loa (eye worm) peptidase family M13 containing protein 0.007 0.0141 0.0133
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0605 0.1748 0.2905
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0014
Loa Loa (eye worm) hypothetical protein 0.0095 0.0215 0.0208
Giardia lamblia Encystation-specific protease 0.0335 0.0938 0.2491
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0137 0.0341 0.0334
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0025 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0148 0.0375 0.0375
Schistosoma mansoni ap endonuclease 0.0039 0.0046 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0218 0.0218
Onchocerca volvulus 0.003 0.0018 0.0018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0037 0.0023
Mycobacterium leprae Conserved hypothetical protein 0.0173 0.045 0.1701
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1406 0.4156 1
Plasmodium vivax proteasome subunit beta type-2, putative 0.005 0.0078 0.017
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0055 0.0055
Schistosoma mansoni cell polarity protein 0.0026 0.0008 0.0008
Trypanosoma brucei Component of motile flagella 41 0.0148 0.0375 0.0614
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2018 0.5998 0.5998
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0335 0.0938 0.2491
Plasmodium falciparum plasmepsin VI 0.0031 0.0022 0.0034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Trichomonas vaginalis calmodulin, putative 0.0148 0.0375 0.0886
Loa Loa (eye worm) hypothetical protein 0.007 0.0141 0.0133
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0164 0.0422 0.0414
Schistosoma mansoni cathepsin F (C01 family) 0.1406 0.4156 0.4156
Plasmodium falciparum plasmepsin I 0.0031 0.0022 0.0034
Echinococcus granulosus GPI anchor transamidase 0.021 0.0561 0.0554
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0335 0.0938 0.0938
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0011
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0335 0.0938 0.0931
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Plasmodium falciparum serine repeat antigen 6 0.0335 0.0938 0.2242
Leishmania major calmodulin-like protein 0.0148 0.0375 0.0614
Trypanosoma cruzi cysteine peptidase, putative 0.1406 0.4156 0.4151
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0279 0.0768 0.0761
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0077 0.016 0.0152
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0279 0.0768 0.1833
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Echinococcus granulosus glycoprotein Antigen 5 0.0111 0.0264 0.0256
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.021 0.0561 0.0561
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0947 0.2778 0.2772
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0114
Schistosoma mansoni neprilysin 0.0025 0.0004 0.0004
Giardia lamblia Cathepsin L precursor 0.0335 0.0938 0.2491
Trypanosoma brucei cysteine peptidase C (CPC) 0.1267 0.374 0.6231
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0218 0.0218
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0138
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0011
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.026 0.071 0.0703
Trichomonas vaginalis calcium binding protein, putative 0.0148 0.0375 0.0886
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Schistosoma mansoni calpain (C02 family) 0.0947 0.2778 0.2778
Echinococcus multilocularis expressed protein 0.0816 0.2382 0.2376
Schistosoma mansoni chromatin regulatory protein sir2 0.0137 0.0341 0.0341
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0164 0.0422 0.0414
Echinococcus multilocularis calumenin 0.0151 0.0382 0.0375
Echinococcus granulosus proteasome prosome macropain 0.0164 0.0422 0.0414
Echinococcus multilocularis calpain 5 0.0947 0.2778 0.2772
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0077 0.016 0.0366
Loa Loa (eye worm) hypothetical protein 0.0335 0.0938 0.0931
Giardia lamblia Cathepsin L-like protease 0.0335 0.0938 0.2491
Brugia malayi prolyl oligopeptidase family protein 0.0273 0.075 0.0743
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0037 0.007
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0342 0.0335
Plasmodium vivax proteasome subunit beta type-1, putative 0.0077 0.016 0.0366
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0335 0.0938 0.0931
Plasmodium falciparum plasmepsin IV 0.0031 0.0022 0.0034
Mycobacterium ulcerans hypothetical protein 0.0173 0.045 0.1741
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3349 1 1
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2778 0.2772
Giardia lamblia Thymus-specific serine protease precursor 0.0041 0.0052 0.0119
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0011
Leishmania major hypothetical protein, conserved 0.0036 0.0037 0.0049
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Trypanosoma cruzi centrin, putative 0.0152 0.0386 0.0379
Onchocerca volvulus Cathepsin L homolog 0.1406 0.4156 0.6924
Echinococcus multilocularis enteropeptidase 0.0111 0.0264 0.0256
Echinococcus multilocularis chromatin regulatory protein sir2 0.0124 0.0301 0.0294
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0264
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0279 0.0768 0.1833
Schistosoma mansoni cathepsin C 0.0335 0.0938 0.0938
Echinococcus multilocularis cysteine protease 0.1406 0.4156 0.4151
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0335 0.0938 0.2242
Trypanosoma cruzi calmodulin, putative 0.0148 0.0375 0.0368
Trichomonas vaginalis peptide N-glycanase, putative 0.0173 0.045 0.1067
Entamoeba histolytica prolyl oligopeptidase family protein 0.0273 0.075 0.1791
Toxoplasma gondii hypothetical protein 0.0273 0.075 0.124
Schistosoma mansoni hypothetical protein 0.0111 0.0264 0.0264
Trichomonas vaginalis calpain, putative 0.0279 0.0768 0.1833
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.0617 0.1149
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0025 0.0017
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0164 0.0422 0.0691
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0048
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0041
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0605 0.1748 0.1741
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0605 0.1748 0.2905
Trichomonas vaginalis calcium binding protein, putative 0.0148 0.0375 0.0886
Onchocerca volvulus 0.0148 0.0375 0.0613
Trypanosoma cruzi cysteine protease, putative 0.0769 0.2242 0.2236
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0067 0.0059
Echinococcus granulosus cathepsin b 0.3349 1 1
Leishmania major calmodulin, putative 0.0148 0.0375 0.0614
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Brugia malayi Protein kinase domain containing protein 0.0046 0.0067 0.0059
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0046 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Leishmania major calpain protease-like protein 0.0279 0.0768 0.1269
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0605 0.1748 0.2905
Echinococcus granulosus chromatin regulatory protein sir2 0.0124 0.0301 0.0294
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0938 0.2242
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0279 0.0768 0.1269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Entamoeba histolytica cysteine protease, putative 0.0335 0.0938 0.2242
Echinococcus multilocularis calmodulin 0.0148 0.0375 0.0368
Onchocerca volvulus 0.003 0.0018 0.0018
Trypanosoma cruzi conserved protein 0.0279 0.0768 0.0761
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0074 0.0074
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0769 0.2242 0.2236
Entamoeba histolytica hypothetical protein 0.0042 0.0055 0.0114
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.021 0.0561 0.1334
Trypanosoma cruzi major cysteine proteinase, putative 0.0438 0.1247 0.124
Loa Loa (eye worm) hypothetical protein 0.2246 0.6683 0.668
Giardia lamblia Cathepsin B precursor 0.1267 0.374 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0044
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0496 0.1419 0.2356
Plasmodium vivax plasmepsin IV, putative 0.0031 0.0022 0.0034
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Schistosoma mansoni rab 0.0148 0.0375 0.0375
Plasmodium falciparum cysteine proteinase falcipain 3 0.1406 0.4156 1
Toxoplasma gondii centrin 0.0148 0.0375 0.0614
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.021 0.0561 0.0554
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0041
Mycobacterium leprae probable zinc metalloprotease 0.0095 0.0215 0.0735
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.005 0.0078 0.017
Entamoeba histolytica prolyl oligopeptidase family protein 0.0273 0.075 0.1791
Leishmania major centrin, putative,caltractin, putative 0.0148 0.0375 0.0614
Trypanosoma cruzi oligopeptidase b 0.0844 0.2467 0.2461
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.033 0.1251
Echinococcus multilocularis prolyl endopeptidase 0.2018 0.5998 0.5995
Onchocerca volvulus 0.003 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0055 0.0093 0.0086
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0078 0.0078
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0335 0.0938 0.0931
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2673 0.7968 0.7966
Entamoeba histolytica calpain family cysteine protease, putative 0.0279 0.0768 0.1833
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0055 0.0048
Brugia malayi Cathepsin L-like precursor 0.0972 0.2851 0.2846
Schistosoma mansoni hypothetical protein 0.0279 0.0768 0.0768
Plasmodium vivax vivapain-2 0.1406 0.4156 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0014
Brugia malayi Trypsin family protein 0.0111 0.0264 0.0256
Toxoplasma gondii calmodulin CAM1 0.0151 0.0382 0.0626
Plasmodium falciparum serine repeat antigen 1 0.0335 0.0938 0.2242
Brugia malayi Cell death protein 3 precursor 0.0093 0.0207 0.02
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0335 0.0938 0.2242
Schistosoma mansoni neuronal calcium sensor 0.0148 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0335 0.0938 0.0931
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0218 0.0218
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0279 0.0768 0.0761
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0148 0.0375 0.0886
Leishmania major hypothetical protein, conserved 0.0148 0.0375 0.0614
Loa Loa (eye worm) ctsf protein 0.1406 0.4156 0.4151
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0046 0.5
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0048 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0093 0.0207 0.02
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0774 0.0767
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0055 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0938 0.2242
Plasmodium vivax calpain, putative 0.0947 0.2778 0.6678
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0264
Leishmania major silent information regulator 2, putative 0.0124 0.0301 0.049
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.0761
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0774 0.0767
Schistosoma mansoni hypothetical protein 0.0025 0.0004 0.0004
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.0301 0.0294
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0148 0.0375 0.0886
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0264
Leishmania major calmodulin, putative 0.0148 0.0375 0.0614
Entamoeba histolytica cysteine proteinase, putative 0.0769 0.2242 0.5387
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0095 0.0215 0.037
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Schistosoma mansoni cathepsin S (C01 family) 0.0335 0.0938 0.0938
Brugia malayi cathepsin Z-like cysteine proteinase 0.0335 0.0938 0.0931
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0335 0.0938 0.2242
Entamoeba histolytica cysteine protease, putative 0.0335 0.0938 0.2242
Schistosoma mansoni neprilysin-2 (M13 family) 0.0048 0.0074 0.0074
Onchocerca volvulus 0.0759 0.2211 0.3678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0938 0.2242
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0046 0.0064
Brugia malayi Cathepsin L-like cysteine proteinase 0.0972 0.2851 0.2846
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Echinococcus granulosus dnaJ subfamily B 0.0432 0.1227 0.122
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2778 0.2772
Giardia lamblia Cysteine protease 0.0335 0.0938 0.2491
Mycobacterium tuberculosis Conserved protein 0.0036 0.0037 0.0023
Echinococcus granulosus cathepsin L 0.0769 0.2242 0.2236
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0048
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.0301 0.0708
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0025 0.0029
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0279 0.0768 0.0761
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1267 0.374 0.3736
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0375 0.0886
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.021 0.0561 0.0924
Trypanosoma brucei calpain-like protein, putative 0.0947 0.2778 0.4624
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0279 0.0768 0.0761
Echinococcus multilocularis tumor protein p63 0.0373 0.1052 0.1045
Loa Loa (eye worm) hypothetical protein 0.0072 0.0146 0.0138
Onchocerca volvulus Peroxidasin homolog 0.0281 0.0774 0.1279
Plasmodium vivax aspartyl protease, putative 0.0031 0.0022 0.0034
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0335 0.0938 0.2491
Loa Loa (eye worm) hypothetical protein 0.0273 0.075 0.0743
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0137 0.0341 0.0893
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1406 0.4156 0.4151
Echinococcus granulosus expressed protein 0.0816 0.2382 0.2376
Echinococcus granulosus neuronal calcium sensor 0.0148 0.0375 0.0368
Mycobacterium ulcerans hypothetical protein 0.0036 0.0037 0.0049
Brugia malayi calpain D 0.0279 0.0768 0.0761
Loa Loa (eye worm) hypothetical protein 0.0096 0.0218 0.0211
Giardia lamblia Cathepsin B precursor 0.0335 0.0938 0.2491
Brugia malayi prolyl oligopeptidase family protein 0.0605 0.1748 0.1741
Onchocerca volvulus 0.0046 0.0067 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0037 0.0049
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0176 0.0458 0.0451
Echinococcus multilocularis calmodulin 0.0148 0.0375 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0052 0.0107
Echinococcus granulosus calbindin 32 0.0151 0.0382 0.0375
Entamoeba histolytica cysteine protease, putative 0.1406 0.4156 1
Onchocerca volvulus 0.0335 0.0938 0.1552
Echinococcus granulosus EF HAND 1 calcium binding site 0.0148 0.0375 0.0368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.2242 0.5387
Trichomonas vaginalis calmodulin-2, putative 0.0148 0.0375 0.0886
Plasmodium vivax aspartyl protease, putative 0.0113 0.0269 0.063
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Echinococcus multilocularis EF hand domain containing family member A2 0.0151 0.0382 0.0375
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0273 0.075 0.075
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0761 0.2217 0.2211
Onchocerca volvulus 0.0151 0.0382 0.0625
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0046 0.0038
Schistosoma mansoni peroxidasin 0.0281 0.0774 0.0774
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0041
Trypanosoma cruzi kinesin, putative 0.0668 0.1939 0.1933
Brugia malayi PAN domain containing protein 0.003 0.0018 0.0011
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0037 0.0029
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0025 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0335 0.0938 0.2242
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0041
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0111 0.0264 0.0264
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1406 0.4156 0.4151
Brugia malayi Calmodulin-like protein 0.0148 0.0375 0.0368
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Trypanosoma brucei calpain, putative 0.0279 0.0768 0.1269
Leishmania major hypothetical protein, unknown function 0.0279 0.0768 0.1269
Plasmodium vivax unspecified product 0.0335 0.0938 0.2242
Schistosoma mansoni inhibitor of apoptosis protein 0.0176 0.0458 0.0458
Echinococcus granulosus neurocalcin 0.0148 0.0375 0.0368
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0055 0.0048
Leishmania major i/6 autoantigen-like protein 0.0148 0.0375 0.0614
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0273 0.075 0.1791
Plasmodium vivax vivapain-2 0.1406 0.4156 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Schistosoma mansoni calmodulin related calcium binding protein 0.0148 0.0375 0.0375
Loa Loa (eye worm) calpain family protein 1 0.2525 0.7522 0.752
Onchocerca volvulus 0.0972 0.2851 0.4746
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Leishmania major cathepsin L-like protease 0.1406 0.4156 0.6924
Brugia malayi Cathepsin L-like precursor 0.0972 0.2851 0.2846
Echinococcus granulosus proteasome prosome macropain subunit beta 0.005 0.0078 0.0071
Onchocerca volvulus 0.003 0.0018 0.0018
Echinococcus multilocularis proteasome (prosome, macropain) 0.0164 0.0422 0.0414
Onchocerca volvulus 0.0111 0.0264 0.0427
Onchocerca volvulus Legumain homolog 0.0905 0.2652 0.4414
Giardia lamblia Proteasome subunit beta type 1 0.0077 0.016 0.0407
Onchocerca volvulus 0.0167 0.0431 0.0707
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0218 0.0211
Onchocerca volvulus Neurogenic locus notch homolog 0.0026 0.0009 0.0001
Echinococcus granulosus glycogen phosphorylase 0.0112 0.0266 0.0259
Plasmodium vivax centrin-1, putative 0.0148 0.0375 0.0886
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0011
Trypanosoma cruzi caltractin, putative 0.0148 0.0375 0.0368
Echinococcus multilocularis glycoprotein Antigen 5 0.0111 0.0264 0.0256
Plasmodium falciparum serine repeat antigen 7 0.0335 0.0938 0.2242
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0148 0.0375 0.0368
Toxoplasma gondii cathepsin CPL 0.1406 0.4156 0.6924
Plasmodium falciparum peptidase, putative 0.0273 0.075 0.1791
Loa Loa (eye worm) hypothetical protein 0.0972 0.2851 0.2846
Entamoeba histolytica prolyl oligopeptidase family protein 0.0273 0.075 0.1791
Onchocerca volvulus 0.1406 0.4156 0.6924
Schistosoma mansoni glycogen phosphorylase 0.0112 0.0266 0.0266
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0037 0.0023
Loa Loa (eye worm) hypothetical protein 0.0972 0.2851 0.2846
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0046 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0972 0.2851 0.6855
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0055 0.0055
Leishmania major cathepsin L-like protease 0.1508 0.4465 0.744
Plasmodium falciparum plasmepsin II 0.0031 0.0022 0.0034
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0078 0.0078
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0279 0.0768 0.1269
Brugia malayi carbohydrate phosphorylase 0.0112 0.0266 0.0259
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.033 0.1251
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0095 0.0215 0.0208
Schistosoma mansoni notch 0.0026 0.0008 0.0008
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0176 0.0458 0.0451
Giardia lamblia Cathepsin B precursor 0.1267 0.374 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.033 0.1251
Onchocerca volvulus Cathepsin L homolog 0.0335 0.0938 0.1552
Trypanosoma brucei proteasome subunit beta type-2, putative 0.005 0.0078 0.0118
Giardia lamblia Cysteine protease 0.0335 0.0938 0.2491
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0342 0.0335
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0037 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0335 0.0938 0.2242
Schistosoma mansoni centrin 0.0148 0.0375 0.0375
Onchocerca volvulus 0.0111 0.0264 0.0427
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0055 0.0048
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0052 0.0107
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Plasmodium falciparum serine repeat antigen 2 0.0335 0.0938 0.2242
Loa Loa (eye worm) hypothetical protein 0.0111 0.0264 0.0256
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0905 0.2652 0.6375
Brugia malayi hypothetical protein 0.0031 0.0022 0.0014
Onchocerca volvulus Cathepsin F homolog 0.1406 0.4156 0.6924
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.0022 0.0022
Loa Loa (eye worm) calmodulin-like protein 0.0148 0.0375 0.0368
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Schistosoma mansoni caspase-7 (C14 family) 0.0093 0.0207 0.0207
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0037 0.0023
Echinococcus granulosus endothelin converting enzyme 1 0.0095 0.0215 0.0208
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0046 0.0038
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0055 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0341 0.0804
Echinococcus multilocularis dnaJ subfamily B 0.0432 0.1227 0.122
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0046 0.0102
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0041 0.0052 0.0074
Giardia lamblia Cathepsin L precursor 0.0335 0.0938 0.2491
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0041 0.0052 0.0107
Giardia lamblia Hypothetical protein 0.0151 0.0382 0.1004
Brugia malayi EF hand family protein 0.0151 0.0382 0.0375
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0905 0.2652 0.6375
Brugia malayi transcriptional regulator, Sir2 family protein 0.0124 0.0301 0.0294
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0055 0.0048
Mycobacterium tuberculosis Conserved protein 0.0173 0.045 0.0825
Brugia malayi Papain family cysteine protease containing protein 0.0335 0.0938 0.0931
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0148 0.0375 0.0886
Toxoplasma gondii subtilisin SUB12 0.003 0.0018 0.0018
Echinococcus multilocularis microtubule associated protein 2 0.1491 0.4413 0.4409
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0114
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0301 0.0301
Echinococcus multilocularis centrin 2 0.0148 0.0375 0.0368
Echinococcus multilocularis hypothetical protein 0.0947 0.2778 0.2772
Onchocerca volvulus 0.0054 0.0091 0.0139
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3349 1 1
Schistosoma mansoni hypothetical protein 0.0173 0.045 0.045
Mycobacterium tuberculosis Conserved hypothetical protein 0.0173 0.045 0.0825
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0025 0.0017
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0264 0.0264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0938 0.2242
Brugia malayi cathepsin F-like cysteine proteinase 0.0335 0.0938 0.0931
Echinococcus granulosus cathepsin L 0.0335 0.0938 0.0931
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0048 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0382 0.1079 0.1072
Trypanosoma cruzi Aph-1 protein, putative 0.0101 0.0233 0.0226
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.021 0.0561 0.1334
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0844 0.2467 0.474
Onchocerca volvulus 0.0093 0.0207 0.0333
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0279 0.0768 0.1269
Loa Loa (eye worm) hypothetical protein 0.0264 0.0723 0.0716
Schistosoma mansoni calpain-7 (C02 family) 0.095 0.2787 0.2787
Toxoplasma gondii microneme protein MIC17B 0.003 0.0018 0.0018
Echinococcus multilocularis transmembrane protease serine 3 0.0111 0.0264 0.0256
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0025 0.0025
Giardia lamblia Hypothetical protein 0.0335 0.0938 0.2491
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0055 0.0048
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0148 0.0375 0.0368
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0037 0.0049
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni memapsin-2 (A01 family) 0.0488 0.1396 0.1396
Brugia malayi Cytochrome P450 family protein 0.0035 0.0033 0.0026
Loa Loa (eye worm) hypothetical protein 0.021 0.0561 0.0554
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0031 0.0022 0.0014
Leishmania major cathepsin L-like protease 0.1406 0.4156 0.6924
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1406 0.4156 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0055 0.0048
Loa Loa (eye worm) hypothetical protein 0.0281 0.0774 0.0767
Brugia malayi Peptidase family M13 containing protein 0.0095 0.0215 0.0208
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0947 0.2778 0.2772
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0055 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1406 0.4156 1
Brugia malayi Papain family cysteine protease containing protein 0.1406 0.4156 0.4151
Trypanosoma cruzi cysteine proteinase, putative 0.0769 0.2242 0.2236
Toxoplasma gondii aspartyl protease ASP1 0.0031 0.0022 0.0023
Echinococcus granulosus peroxidasin 0.0281 0.0774 0.0767
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0018 0.0011
Onchocerca volvulus 0.1406 0.4156 0.6924
Echinococcus multilocularis calpain 0.0947 0.2778 0.2772
Schistosoma mansoni mitochondrial solute carrier 0.0148 0.0375 0.0375
Trichomonas vaginalis glycogen phosphorylase, putative 0.0112 0.0266 0.0624
Toxoplasma gondii hypothetical protein 0.003 0.0018 0.0018
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0037 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Onchocerca volvulus 0.0031 0.0022 0.0023
Trypanosoma cruzi I/6 autoantigen, putative 0.0148 0.0375 0.0368
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0176 0.0458 0.0451
Echinococcus multilocularis cathepsin L 0.0769 0.2242 0.2236
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0279 0.0768 0.0761
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.0301 0.0294
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.0342 0.0335
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0844 0.2467 1
Leishmania major cysteine peptidase A (CPA) 0.1406 0.4156 0.6924
Echinococcus multilocularis neurocalcin 0.0148 0.0375 0.0368
Entamoeba histolytica cysteine protease, putative 0.0769 0.2242 0.5387
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3349 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0335 0.0938 0.2242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1508 0.4465 0.744
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0037 0.0023
Loa Loa (eye worm) sirtuin 4 0.0032 0.0025 0.0017
Schistosoma mansoni hypothetical protein 0.0148 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0434 0.1234 0.1227
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0033 0.0026
Schistosoma mansoni ef hand domain family member A2 0.0148 0.0375 0.0375
Echinococcus multilocularis inhibitor of apoptosis protein 0.0176 0.0458 0.0451
Trichomonas vaginalis centrin, putative 0.0148 0.0375 0.0886
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0148 0.0375 0.0368
Trypanosoma cruzi 20S proteasome subunit 0.005 0.0078 0.0071
Trypanosoma cruzi prolyl endopeptidase 0.2018 0.5998 0.5995
Brugia malayi hypothetical protein 0.0281 0.0774 0.0767
Brugia malayi Pre-SET motif family protein 0.0667 0.1933 0.1927
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0041 0.0052 0.0044
Schistosoma mansoni hypothetical protein 0.0695 0.202 0.202
Plasmodium falciparum cysteine proteinase falcipain 1 0.0769 0.2242 0.5387
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0279 0.0768 0.0761
Entamoeba histolytica glycogen phosphorylase, putative 0.0112 0.0266 0.0624
Schistosoma mansoni cpg binding protein 0.0032 0.0025 0.0025
Onchocerca volvulus 0.0173 0.045 0.0738
Schistosoma mansoni cercarial elastase (S01 family) 0.0111 0.0264 0.0264
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0335 0.0938 0.0938
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0335 0.0938 0.2242
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0031 0.0022 0.0014
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.033 0.0539
Entamoeba histolytica hypothetical protein 0.0335 0.0938 0.2242
Trichomonas vaginalis calcium binding proteins, putative 0.0148 0.0375 0.0886
Trypanosoma brucei centrin, putative 0.0148 0.0375 0.0614
Plasmodium vivax aspartyl protease, putative 0.0113 0.0269 0.063
Onchocerca volvulus 0.003 0.0018 0.0018
Echinococcus granulosus cathepsin l1 0.1406 0.4156 0.4151
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0335 0.0938 0.2242
Loa Loa (eye worm) hypothetical protein 0.0279 0.0768 0.0761

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 41 % Stimulation of prostate weight in Sprague-Dawley rat at 2 mg/day, po relative to testosterone ChEMBL. 16959487
Activity (functional) = 66 % Stimulation of levator ani muscle weight in Sprague-Dawley rat at 2 mg/day relative to testosterone ChEMBL. 16959487
Inhibition (functional) = 28 % Inhibition of prostate weight in Sprague-Dawley rat at 2 mg/day, po relative to control ChEMBL. 16959487

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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