Detailed information for compound 46134

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 487.633 | Formula: C30H37N3O3
  • H donors: 2 H acceptors: 2 LogP: 5.72 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1OC1CCCC1)[C@@H](c1cccc(c1)NC(=O)NC(C)(C)C)Cc1ccncc1
  • InChi: 1S/C30H37N3O3/c1-30(2,3)33-29(34)32-24-9-7-8-22(19-24)26(18-21-14-16-31-17-15-21)23-12-13-27(35-4)28(20-23)36-25-10-5-6-11-25/h7-9,12-17,19-20,25-26H,5-6,10-11,18H2,1-4H3,(H2,32,33,34)/t26-/m1/s1
  • InChiKey: ZJQKZGNVEFZUMR-AREMUKBSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens phosphodiesterase 4A, cAMP-specific Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4C, putative Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase, isoform F, putative Get druggable targets OG5_128242 All targets in OG5_128242
Neospora caninum cAMP-specific phosphodiesterase, putative Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein Get druggable targets OG5_128242 All targets in OG5_128242
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum IPR002073,3'5'-cyclic nucleotide phosphodiesterase,domain-containing Get druggable targets OG5_128242 All targets in OG5_128242
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_128242 All targets in OG5_128242
Cryptosporidium parvum membrane associated HD superfamily cyclic nucleotide phosphodiesterase domain containing protein Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax histone deacetylase, putative 0.0077 0.0126 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0911 0.198 0.6547
Echinococcus multilocularis survival motor neuron protein 1 0.0522 0.1116 0.1116
Schistosoma mansoni cpg binding protein 0.0033 0.0027 0.0032
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0327 0.0682 0.0827
Echinococcus granulosus chromatin regulatory protein sir2 0.0253 0.0517 0.0516
Echinococcus granulosus histone deacetylase 6 0.0225 0.0455 0.0455
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Entamoeba histolytica calpain large subunit domain III containing protein 0.0795 0.1723 0.6006
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0024 0.0007 0.0008
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.0007 0.0043
Echinococcus multilocularis peroxidasin 0.0275 0.0566 0.0566
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0094 0.0162 0.0162
Loa Loa (eye worm) animal heme peroxidase 0.0275 0.0566 0.0687
Loa Loa (eye worm) beta-lactamase 0.0037 0.0037 0.0044
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0171 0.0171
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0377 0.0793 0.2767
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0125 0.0233 0.075
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.007 0.0084
Echinococcus multilocularis calumenin 0.0185 0.0365 0.0365
Leishmania major programmed cell death 6 protein-like protein 0.0182 0.0358 0.089
Trichomonas vaginalis conserved hypothetical protein 0.0327 0.0682 0.224
Onchocerca volvulus 0.1308 0.2865 0.6936
Schistosoma mansoni caspase-7 (C14 family) 0.0214 0.0431 0.0523
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0037 0.01
Trypanosoma brucei centrin, putative 0.0182 0.0358 0.0882
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.01 0.0176 0.1047
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0024 0.0007 0.0008
Loa Loa (eye worm) histone deacetylase 0.0212 0.0426 0.0516
Plasmodium vivax glutathione reductase, putative 0.1088 0.2375 0.8288
Loa Loa (eye worm) hypothetical protein 0.0398 0.0839 0.1017
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.01 0.0176 0.0515
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0098 0.0172 0.0172
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0353
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.015 0.0503
Entamoeba histolytica histone deacetylase, putative 0.0125 0.0233 0.0791
Echinococcus granulosus subfamily T1A non peptidase ue 0.0024 0.0007 0.0006
Plasmodium vivax plasmepsin V, putative 0.0054 0.0074 0.0258
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0071 0.0111 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0267 0.0548 0.0665
Toxoplasma gondii cathepsin CPC2 0.0327 0.0682 0.1696
Giardia lamblia Cathepsin B precursor 0.0327 0.0682 0.224
Echinococcus granulosus Proteasome subunit alpha beta 0.0024 0.0007 0.0006
Echinococcus granulosus enteropeptidase 0.0152 0.0291 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0023 0.0028
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0065 0.0099 0.0245
Entamoeba histolytica calcium binding family protein 0.0182 0.0358 0.123
Trypanosoma cruzi oligopeptidase b 0.0778 0.1684 0.2042
Toxoplasma gondii EGF family domain-containing protein 0.0025 0.0011 0.0026
Echinococcus granulosus leucine aminopeptidase protein 0.0113 0.0205 0.0205
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0024 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0012
Brugia malayi hypothetical protein 0.0174 0.0342 0.0415
Leishmania major calpain protease-like protein 0.0333 0.0695 0.1729
Trypanosoma cruzi hypothetical protein, conserved 0.01 0.0176 0.0214
Leishmania major proteasome beta 2 subunit, putative 0.0024 0.0007 0.0016
Echinococcus granulosus delta-like protein 1 0.0025 0.0011 0.001
Brugia malayi cathepsin L-like cysteine proteinase 0.0327 0.0682 0.0827
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0024 0.0007 0.0016
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.01 0.0176 0.0176
Trypanosoma cruzi caltractin, putative 0.0182 0.0358 0.0434
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0024 0.0007 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus multilocularis EF hand domain containing family member A2 0.0185 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0045 0.0053 0.0065
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0193 0.0384 0.0466
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0327 0.0682 0.224
Onchocerca volvulus 0.0098 0.0172 0.0417
Plasmodium falciparum serine repeat antigen 2 0.0327 0.0682 0.2379
Onchocerca volvulus Glycogen phosphorylase homolog 0.0114 0.0208 0.0504
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0398 0.0839 0.1017
Onchocerca volvulus Peroxidase homolog 0.0275 0.0566 0.137
Echinococcus multilocularis neurogenic locus notch protein 4 0.0025 0.0011 0.001
Brugia malayi EGF-like domain containing protein 0.0025 0.0011 0.0013
Toxoplasma gondii troponin c, isotype gamma, putative 0.0182 0.0358 0.089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0377 0.0793 0.0793
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0024 0.0007 0.0008
Schistosoma mansoni chromatin regulatory protein sir2 0.0253 0.0517 0.0626
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0023 0.0027
Mycobacterium leprae Conserved hypothetical protein 0.0297 0.0616 0.3655
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0024 0.0007 0.0007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0023 0.0023
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.01 0.0176 0.0214
Schistosoma mansoni polycystin 1-related 0.0062 0.0091 0.011
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1021 0.2225 0.5386
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0094 0.0162 0.0162
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0063 0.0094 0.0292
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.0007 0.0021
Plasmodium vivax calpain, putative 0.1129 0.2464 0.8602
Trichomonas vaginalis esterase, putative 0.0037 0.0037 0.01
Onchocerca volvulus Peroxidasin homolog 0.0275 0.0566 0.137
Loa Loa (eye worm) blistered cuticle protein 3 0.0275 0.0566 0.0687
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0065 0.0099 0.0098
Plasmodium vivax ferrodoxin reductase, putative 0.01 0.0176 0.0616
Loa Loa (eye worm) animal heme peroxidase 0.0275 0.0566 0.0687
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0377 0.0793 0.2313
Brugia malayi hypothetical protein 0.0273 0.0562 0.0681
Trypanosoma cruzi cysteine proteinase, putative 0.0725 0.1567 0.19
Schistosoma mansoni chromatin regulatory protein sir2 0.0065 0.0099 0.0119
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0094 0.0162 0.0196
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0037 0.0044
Trichomonas vaginalis histone deacetylase, putative 0.0125 0.0233 0.075
Loa Loa (eye worm) cytochrome P450 0.0024 0.0007 0.0009
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0053 0.0053
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0063 0.0094 0.0292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0725 0.1567 0.5177
Echinococcus granulosus EF hand domain containing family member A2 0.0182 0.0358 0.0358
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.0007 0.0021
Onchocerca volvulus 0.0031 0.0023 0.0055
Mycobacterium tuberculosis Long conserved protein 0.0297 0.0616 0.1796
Onchocerca volvulus 0.0327 0.0682 0.165
Plasmodium falciparum proteasome subunit beta type-5 0.0164 0.0319 0.1112
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0024 0.0007 0.0008
Trypanosoma cruzi I/6 autoantigen, putative 0.0182 0.0358 0.0434
Loa Loa (eye worm) hypothetical protein 0.1828 0.402 0.4877
Giardia lamblia Glycogen phosphorylase 0.0114 0.0208 0.067
Echinococcus granulosus proteasome subunit alpha type 2 0.0024 0.0007 0.0006
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.0007 0.0043
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0013
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Trichomonas vaginalis calmodulin-2, putative 0.0182 0.0358 0.1166
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.004 0.0424
Loa Loa (eye worm) hypothetical protein 0.0094 0.0162 0.0196
Trypanosoma cruzi metacaspase 5, putative 0.0071 0.0111 0.0134
Loa Loa (eye worm) hypothetical protein 0.0045 0.0053 0.0065
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0024 0.0007 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0267 0.0548 0.1913
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Schistosoma mansoni hypothetical protein 0.0182 0.0358 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0358 0.1166
Loa Loa (eye worm) proteasome subunit beta type 1 0.0078 0.0127 0.0154
Loa Loa (eye worm) proteasome subunit beta type 2 0.005 0.0066 0.008
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0011 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.0961
Brugia malayi EGF-like domain containing protein 0.0025 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.3006 0.6641 0.8056
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0054 0.0074 0.009
Echinococcus granulosus sulfide:quinone oxidoreductase 0.01 0.0176 0.0176
Mycobacterium leprae putative cytochrome p450 0.0024 0.0007 0.0043
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0055 0.0161
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0065 0.0099 0.0119
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Giardia lamblia Hypothetical protein 0.0297 0.0616 0.2021
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0023 0.0028
Trichomonas vaginalis calmodulin, putative 0.0182 0.0358 0.1166
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0113 0.0205 0.1215
Echinococcus granulosus Dipeptidyl peptidase 9 0.0649 0.1399 0.1398
Echinococcus multilocularis histone deacetylase 8 0.0077 0.0126 0.0125
Plasmodium falciparum plasmepsin VII 0.0054 0.0074 0.0258
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0267 0.0548 0.1355
Leishmania major cathepsin L-like protease 0.1308 0.2865 0.7126
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.1177 0.2571 0.2571
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0024 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0063 0.0094 0.0094
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.01 0.0176 0.0214
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.01 0.0176 0.043
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0023 0.0027
Brugia malayi proteasome subunit alpha type 4 0.0024 0.0007 0.0008
Schistosoma mansoni slit 0.0025 0.0011 0.0013
Plasmodium vivax aspartyl protease, putative 0.0298 0.0616 0.2149
Leishmania major phospholipase c-like protein 0.0182 0.0358 0.089
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0138 0.026 0.026
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0023 0.0028
Loa Loa (eye worm) apoptosis regulator protein 0.0094 0.0162 0.0196
Brugia malayi peptidase family M13 containing protein 0.0024 0.0006 0.0008
Trichomonas vaginalis centrin, putative 0.0182 0.0358 0.1166
Echinococcus granulosus Mastin 0.0152 0.0291 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0023 0.0028
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0053 0.0065
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0333 0.0695 0.2285
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0049 0.0063 0.0076
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1129 0.2464 0.2989
Brugia malayi carbohydrate phosphorylase 0.0114 0.0208 0.0253
Loa Loa (eye worm) hypothetical protein 0.0045 0.0053 0.0065
Echinococcus multilocularis dnaJ subfamily B 0.044 0.0933 0.0933
Leishmania major histone deacetylase, putative 0.0125 0.0233 0.0578
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0045 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0148 0.0283 0.0343
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0024 0.0007 0.0007
Brugia malayi calpain family protein 1 0.3006 0.6641 0.8056
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.01 0.0176 0.0616
Toxoplasma gondii selenide, water dikinase 0.01 0.0176 0.0439
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0327 0.0682 0.224
Schistosoma mansoni reticulocalbin 0.0182 0.0358 0.0434
Loa Loa (eye worm) hypothetical protein 0.0062 0.0091 0.011
Mycobacterium tuberculosis Conserved protein 0.0297 0.0616 0.1796
Brugia malayi Alcohol dehydrogenase class III 0.0162 0.0314 0.038
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.004 0.004
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0023 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0172 0.0209
Echinococcus multilocularis apoptotic protease activating factor 1 0.0144 0.0274 0.0274
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0024 0.0007 0.0022
Loa Loa (eye worm) programmed cell death protein 6 0.0185 0.0365 0.0443
Entamoeba histolytica hypothetical protein, conserved 0.0267 0.0548 0.1895
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0182 0.0358 0.1166
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Trichomonas vaginalis calcium binding protein, putative 0.0182 0.0358 0.1166
Loa Loa (eye worm) prolyl oligopeptidase 0.1021 0.2225 0.2699
Trypanosoma brucei calpain-like protein, putative 0.1129 0.2464 0.6126
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0024 0.0007 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0037 0.0128
Loa Loa (eye worm) zinc metallopeptidase 4 0.0024 0.0006 0.0008
Onchocerca volvulus 0.0031 0.0023 0.0055
Trypanosoma brucei proteasome beta 7 subunit 0.0024 0.0007 0.0007
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.01 0.0176 0.0439
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.004 0.0111
Echinococcus granulosus glycogen phosphorylase 0.0114 0.0208 0.0208
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0091 0.0091
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0004 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0682 0.224
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0327 0.0682 0.0827
Echinococcus granulosus prolyl endopeptidase 0.1828 0.402 0.402
Toxoplasma gondii cathepsin B 0.1378 0.3021 0.7513
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0037 0.01
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0377 0.0793 0.1964
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0053 0.0065
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0045 0.0053 0.0065
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0023 0.0004 0.0011
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0024 0.0007 0.0008
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0012 0.0019
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0039 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0377 0.0793 0.1964
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0193 0.0384 0.0384
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0065 0.0099 0.0098
Echinococcus multilocularis proteasome subunit beta type 7 0.0024 0.0007 0.0006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.01 0.0176 0.0515
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0023 0.0023
Trichomonas vaginalis calcium binding protein, putative 0.0182 0.0358 0.1166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Toxoplasma gondii exonuclease III APE 0.0039 0.004 0.0099
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0164 0.0319 0.0386
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0024 0.0007 0.0008
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.001 0.006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1663 0.3653 0.3653
Loa Loa (eye worm) hypothetical protein 0.0125 0.0233 0.0282
Onchocerca volvulus Prolyl endopeptidase homolog 0.1828 0.402 0.9733
Echinococcus multilocularis caspase 2 0.0214 0.0431 0.0431
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0045 0.0053 0.0065
Giardia lamblia Cathepsin L-like protease 0.0327 0.0682 0.224
Onchocerca volvulus 0.0031 0.0023 0.0056
Schistosoma mansoni rab6-interacting 0.0062 0.0091 0.011
Trypanosoma brucei Calpain-like protein CALP1.3 0.0333 0.0695 0.1721
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0024 0.0007 0.0016
Trypanosoma brucei metacaspase MCA2 0.0071 0.0111 0.0267
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0649 0.1399 0.1696
Brugia malayi TAR-binding protein 0.0068 0.0104 0.0127
Plasmodium vivax centrin-1, putative 0.0182 0.0358 0.1249
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0164 0.0319 0.0784
Echinococcus granulosus proteasome subunit beta type 7 0.0024 0.0007 0.0006
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.01 0.0176 0.0214
Loa Loa (eye worm) transcriptional regulator 0.0065 0.0099 0.0119
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0142
Onchocerca volvulus 0.0048 0.0061 0.0147
Mycobacterium ulcerans dehydrogenase 0.01 0.0176 0.1047
Schistosoma mansoni septate junction protein 0.0025 0.0011 0.0013
Onchocerca volvulus Peroxidase homolog 0.0275 0.0566 0.137
Mycobacterium ulcerans proteasome PrcB 0.0164 0.0319 0.1892
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.0007 0.0021
Trypanosoma brucei histone deacetylase 1 0.0125 0.0233 0.057
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0111 0.0346
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0071 0.0111 0.0134
Onchocerca volvulus 0.0038 0.0039 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0053 0.0155
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0053 0.0065
Brugia malayi proteasome subunit beta type 3 0.0024 0.0007 0.0008
Plasmodium falciparum plasmepsin IV 0.0054 0.0074 0.0258
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Onchocerca volvulus 0.0911 0.198 0.4793
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0108 0.013
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.0289 0.0289
Entamoeba histolytica thioredoxin reductase, putative 0.01 0.0176 0.0595
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Loa Loa (eye worm) histone deacetylase 1 0.0125 0.0233 0.0282
Schistosoma mansoni hypothetical protein 0.0144 0.0274 0.0332
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0104 0.0127
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0327 0.0682 0.2362
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.01 0.0176 0.043
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0023 0.0028
Toxoplasma gondii proteasome subunit alpha1, putative 0.0024 0.0007 0.0016
Trypanosoma brucei centrin, putative 0.0182 0.0358 0.0882
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0023 0.0028
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.0012
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.01 0.0176 0.0176
Schistosoma mansoni hypothetical protein 0.0048 0.006 0.0073
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0023 0.0028
Toxoplasma gondii microneme protein MIC4 0.0031 0.0023 0.0056
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0327 0.0682 0.0827
Trypanosoma cruzi major cysteine proteinase, putative 0.0327 0.0682 0.0827
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0023 0.0028
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0371 0.0778 0.0944
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0162 0.0314 0.0915
Echinococcus granulosus calumenin 0.0185 0.0365 0.0365
Leishmania major cytochrome p450-like protein 0.0045 0.0053 0.0131
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0055 0.0137
Echinococcus granulosus histone deacetylase 6 0.0212 0.0426 0.0426
Loa Loa (eye worm) Notch2 0.0025 0.0011 0.0013
Echinococcus granulosus protein jagged 1 0.0025 0.0011 0.001
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.005 0.0066 0.0208
Echinococcus granulosus proteasome subunit beta type 6 0.0024 0.0007 0.0006
Leishmania major proteasome alpha 7 subunit, putative 0.0024 0.0007 0.0016
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0182 0.0358 0.0882
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0215 0.0432 0.0432
Leishmania major proteasome alpha 7 subunit, putative 0.0024 0.0007 0.0016
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0004 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus multilocularis enteropeptidase 0.0152 0.0291 0.0291
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.01 0.0176 0.0214
Brugia malayi gamma-secretase subunit aph-1 0.0265 0.0543 0.0658
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0024 0.0007 0.0016
Entamoeba histolytica cysteine proteinase 2 0.0725 0.1567 0.5459
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0027
Onchocerca volvulus Neurogenic locus notch homolog 0.0026 0.0011 0.0027
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0024 0.0007 0.0007
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0024 0.0007 0.0007
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0369 0.0774 0.0774
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.001 0.006
Trichomonas vaginalis calcium binding proteins, putative 0.0182 0.0358 0.1166
Trichomonas vaginalis calmodulin, putative 0.0182 0.0358 0.1166
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0377 0.0793 0.1972
Trypanosoma cruzi centrin, putative 0.0185 0.0366 0.0444
Echinococcus granulosus proteasome subunit alpha type 6 0.0024 0.0007 0.0006
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Schistosoma mansoni hypothetical protein 0.0297 0.0616 0.0747
Echinococcus granulosus glycoprotein Antigen 5 0.0152 0.0291 0.0291
Trichomonas vaginalis myosin light chain 1, putative 0.0182 0.0358 0.1166
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0024 0.0007 0.0022
Onchocerca volvulus 0.1308 0.2865 0.6936
Trichomonas vaginalis conserved hypothetical protein 0.0267 0.0548 0.1797
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.0007 0.0043
Loa Loa (eye worm) hypothetical protein 0.0112 0.0202 0.0245
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0182 0.0358 0.0882
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0682 0.224
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1308 0.2865 1
Mycobacterium ulcerans beta-lactamase 0.0037 0.0037 0.0217
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0071 0.0111 0.0134
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0333 0.0695 0.1721
Onchocerca volvulus 0.0144 0.0274 0.0663
Plasmodium falciparum plasmepsin VIII, putative 0.0054 0.0074 0.0258
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0377 0.0793 0.1964
Loa Loa (eye worm) hypothetical protein 0.0088 0.015 0.0182
Schistosoma mansoni histone deacetylase 4 5 0.0212 0.0426 0.0516
Echinococcus multilocularis Regulator of G protein signaling 20 0.0045 0.0053 0.0053
Giardia lamblia Cathepsin B precursor 0.0327 0.0682 0.224
Leishmania major cathepsin L-like protease 0.1308 0.2865 0.7126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.4516 1 1
Plasmodium vivax unspecified product 0.0725 0.1567 0.5469
Schistosoma mansoni hypothetical protein 0.0333 0.0695 0.0843
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.01 0.0176 0.1047
Mycobacterium tuberculosis Probable peptidase 0.0778 0.1684 0.4915
Loa Loa (eye worm) acetyltransferase 0.0155 0.0299 0.0362
Brugia malayi Cathepsin L-like cysteine proteinase 0.0911 0.198 0.2401
Mycobacterium ulcerans aldehyde dehydrogenase 0.0138 0.026 0.1545
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Echinococcus granulosus cysteine protease 0.0725 0.1567 0.1567
Giardia lamblia Cysteine protease 0.0327 0.0682 0.224
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.005 0.0066 0.008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Brugia malayi Histone deacetylase 1 0.0125 0.0233 0.0282
Mycobacterium ulcerans proteasome PrcA 0.0024 0.0007 0.0038
Echinococcus granulosus centrin 2 0.0182 0.0358 0.0358
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0023 0.0028
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Echinococcus multilocularis neuronal calcium sensor 0.0182 0.0358 0.0358
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0024 0.0007 0.0022
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0094 0.0308
Trypanosoma cruzi hypothetical protein, conserved 0.01 0.0176 0.0214
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3726 0.8244 1
Entamoeba histolytica cysteine protease, putative 0.0327 0.0682 0.2362
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0023 0.0028
Plasmodium falciparum serine repeat antigen 1 0.0327 0.0682 0.2379
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0725 0.1567 0.19
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0024 0.0007 0.0022
Entamoeba histolytica cysteine protease, putative 0.0327 0.0682 0.2362
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0171 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0682 0.224
Toxoplasma gondii aspartyl protease 0.0054 0.0074 0.0184
Loa Loa (eye worm) sirtuin 4 0.0065 0.0099 0.0119
Plasmodium vivax proteasome subunit beta type-1, putative 0.0078 0.0127 0.0444
Entamoeba histolytica disulphide oxidoreductase, putative 0.01 0.0176 0.0595
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0053 0.0053
Entamoeba histolytica calpain family cysteine protease, putative 0.0333 0.0695 0.2409
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0007 0.0009
Trypanosoma brucei oligopeptidase b 0.0778 0.1684 0.4183
Trypanosoma cruzi metacaspase, putative 0.0071 0.0111 0.0134
Mycobacterium tuberculosis Conserved protein 0.0037 0.0037 0.0107
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0023 0.0028
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3006 0.6641 0.8056
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.01 0.0176 0.0564
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0078 0.0127 0.0401
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0039 0.0048
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0024 0.0007 0.0006
Toxoplasma gondii hypothetical protein 0.0031 0.0023 0.0056
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0253 0.0517 0.1692
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0065 0.0099 0.0305
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0065 0.0099 0.0236
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0011 0.0013
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.028 0.0576 0.0576
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0053 0.0065
Trichomonas vaginalis histone deacetylase, putative 0.0125 0.0233 0.075
Trypanosoma cruzi conserved protein 0.0333 0.0695 0.0843
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0327 0.0682 0.2379
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0065 0.0099 0.0098
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.054 0.1156 0.2875
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0024 0.0007 0.0006
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0091 0.0091
Brugia malayi hypothetical protein 0.0045 0.0053 0.0065
Plasmodium vivax proteasome subunit beta type-6, putative 0.0024 0.0007 0.0022
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0152 0.0291 0.0353
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.01 0.0176 0.0214
Echinococcus multilocularis calcium uptake protein 1 0.0185 0.0365 0.0365
Leishmania major proteasome beta 2 subunit, putative 0.005 0.0066 0.0163
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0333 0.0695 0.0843
Trypanosoma brucei metacaspase 5, putative 0.0071 0.0111 0.0267
Leishmania major NADH dehydrogenase, putative 0.01 0.0176 0.0439
Echinococcus granulosus histone deacetylase 1 0.0125 0.0233 0.0233
Echinococcus granulosus glutamate synthase 0.01 0.0176 0.0176
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0649 0.1399 0.3472
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0037 0.0107
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0078 0.0127 0.0317
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0152 0.0291 0.0353
Trypanosoma brucei Calpain-like protein 1.1 0.0333 0.0695 0.1721
Leishmania major proteasome beta-1 subunit, putative 0.0024 0.0007 0.0016
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0024 0.0007 0.0008
Leishmania major oligopeptidase b 0.0778 0.1684 0.4188
Echinococcus multilocularis neural cadherin 0.0025 0.0011 0.001
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0778 0.1684 1
Plasmodium falciparum glutathione reductase 0.0377 0.0793 0.2767
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0327 0.0682 0.2379
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0327 0.0682 0.2379
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0369 0.0774 0.0774
Loa Loa (eye worm) hypothetical protein 0.0911 0.198 0.2401
Toxoplasma gondii calcium-dependent protein kinase 0.0185 0.0365 0.0908
Plasmodium vivax multidomain scavenger receptor, putative 0.0062 0.0091 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.1177 0.2571 0.2571
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0053 0.0065
Plasmodium falciparum flap endonuclease 1 0.0026 0.0012 0.004
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0024 0.0007 0.0008
Trypanosoma brucei protein I/6 0.0182 0.0358 0.0882
Mycobacterium tuberculosis Conserved hypothetical protein 0.0297 0.0616 0.1796
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Schistosoma mansoni hypothetical protein 0.044 0.0933 0.1132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0023 0.0056
Brugia malayi hypothetical protein 0.0054 0.0074 0.009
Brugia malayi EF hand family protein 0.0182 0.0358 0.0434
Onchocerca volvulus Peroxidasin homolog 0.0275 0.0566 0.137
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0023 0.0028
Trypanosoma cruzi histone deacetylase, putative 0.0077 0.0126 0.0152
Echinococcus multilocularis glycoprotein Antigen 5 0.0152 0.0291 0.0291
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus granulosus proteasome prosome macropain 0.0164 0.0319 0.0319
Brugia malayi Cathepsin L-like precursor 0.0911 0.198 0.2401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.0961
Mycobacterium ulcerans monoxygenase 0.01 0.0176 0.1047
Trypanosoma cruzi 20S proteasome subunit 0.005 0.0066 0.008
Loa Loa (eye worm) calpain 0.1129 0.2464 0.2989
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0778 0.1684 0.2042
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.0007 0.0043
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0265 0.0543 0.0658
Brugia malayi Papain family cysteine protease containing protein 0.0725 0.1567 0.19
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0024 0.0007 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0138 0.026 0.1545
Brugia malayi Thioredoxin reductase 0.1088 0.2375 0.288
Plasmodium falciparum serine repeat antigen 7 0.0327 0.0682 0.2379
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0327 0.0682 0.0827
Toxoplasma gondii histone deacetylase SIR2-like 0.0065 0.0099 0.0245
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0024 0.0007 0.0038
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0327 0.0682 0.2379
Echinococcus granulosus calpain A 0.3191 0.7052 0.7052
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0071 0.0111 0.0276
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0024 0.0007 0.0008
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0024 0.0007 0.0008
Brugia malayi fibroinase precursor 0.0327 0.0682 0.0827
Toxoplasma gondii proteasome beta subunit 0.0024 0.0007 0.0016
Brugia malayi proteasome subunit alpha type 2 0.0024 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Echinococcus multilocularis cpg binding protein 0.0033 0.0027 0.0026
Schistosoma mansoni histone deacetylase 0.0125 0.0233 0.0282
Echinococcus multilocularis caspase 0.0215 0.0432 0.0432
Brugia malayi EGF-like domain containing protein 0.0025 0.0011 0.0013
Schistosoma mansoni hypothetical protein 0.0055 0.0077 0.0093
Brugia malayi Pre-SET motif family protein 0.0098 0.0172 0.0209
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0171 0.0208
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Echinococcus multilocularis calpain family protein 1, d 0.2211 0.4872 0.4872
Schistosoma mansoni rab6-interacting 0.0062 0.0091 0.011
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.0012
Brugia malayi hypothetical protein 0.0062 0.0091 0.011
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0024 0.0007 0.0008
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0113 0.0205 0.2522
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.0007 0.0043
Loa Loa (eye worm) hypothetical protein 0.1308 0.2865 0.3475
Onchocerca volvulus 0.0025 0.0011 0.0025
Loa Loa (eye worm) hypothetical protein 0.0174 0.0342 0.0415
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0064 0.0201
Echinococcus granulosus cathepsin L cysteine protease 0.0725 0.1567 0.1567
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0024 0.0007 0.0008
Echinococcus multilocularis cathepsin L 0.0725 0.1567 0.1567
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0053 0.0053
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.0007 0.0043
Loa Loa (eye worm) proteasome subunit beta type 3 0.0024 0.0007 0.0008
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Loa Loa (eye worm) hypothetical protein 0.0398 0.0839 0.1017
Leishmania major proteasome alpha 3 subunit, putative 0.0024 0.0007 0.0016
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0358 0.0434
Toxoplasma gondii subtilisin SUB12 0.0031 0.0023 0.0056
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.0007 0.0043
Brugia malayi cathepsin F-like cysteine proteinase 0.0327 0.0682 0.0827
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0266 0.0546 0.1887
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0037 0.0044
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Onchocerca volvulus 0.0107 0.0191 0.0462
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0296 0.0612 0.3632
Plasmodium falciparum thioredoxin reductase 0.0377 0.0793 0.2767
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0377 0.0793 0.0793
Schistosoma mansoni cpg binding protein 0.0033 0.0027 0.0032
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0113 0.0205 0.0597
Trypanosoma cruzi I/6 autoantigen, putative 0.0182 0.0358 0.0434
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.028 0.0576 0.1891
Trypanosoma cruzi NADH dehydrogenase, putative 0.01 0.0176 0.0214
Brugia malayi calpain D 0.0333 0.0695 0.0843
Loa Loa (eye worm) hypothetical protein 0.0193 0.0384 0.0466
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0054 0.0074 0.0184
Toxoplasma gondii calmodulin CAM1 0.0185 0.0365 0.0908
Leishmania major silent information regulator 2, putative 0.0253 0.0517 0.1285
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0327 0.0682 0.224
Brugia malayi transcriptional regulator, Sir2 family protein 0.0253 0.0517 0.0626
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0023 0.0028
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0333 0.0695 0.2285
Brugia malayi Proteasome A-type and B-type family protein 0.0024 0.0007 0.0008
Echinococcus granulosus endothelin converting enzyme 1 0.0097 0.0169 0.0169
Entamoeba histolytica cysteine proteinase 1, putative 0.0725 0.1567 0.5459
Plasmodium vivax metacaspase 1, putative 0.0071 0.0111 0.0387
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.001 0.006
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0023 0.0023
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.01 0.0176 0.0595
Echinococcus multilocularis endothelin converting enzyme 1 0.0097 0.0169 0.0169
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0097 0.0169 0.0205
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Brugia malayi Histone deacetylase family protein 0.0212 0.0426 0.0516
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0037 0.01
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.0682 0.224
Schistosoma mansoni cathepsin S (C01 family) 0.0327 0.0682 0.0827
Echinococcus granulosus inhibitor of apoptosis protein 0.0193 0.0384 0.0384
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0055 0.0192
Brugia malayi AMP-binding enzyme family protein 0.0025 0.001 0.0012
Echinococcus multilocularis histone deacetylase 6 0.0225 0.0455 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0023 0.0028
Loa Loa (eye worm) hypothetical protein 0.0327 0.0682 0.0827
Leishmania major cathepsin L-like protease 0.1308 0.2865 0.7126
Trypanosoma cruzi NADH dehydrogenase, putative 0.01 0.0176 0.0214
Brugia malayi calpain family protein 1 0.3006 0.6641 0.8056
Schistosoma mansoni hypothetical protein 0.0193 0.0384 0.0466
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0027
Brugia malayi Serine protease Z688.6 precursor 0.0063 0.0094 0.0114
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1226 0.2681 0.3251
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0138 0.026 0.0647
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0065 0.0099 0.0305
Plasmodium falciparum peptidase, putative 0.0267 0.0548 0.1913
Onchocerca volvulus 0.0025 0.0011 0.0025
Echinococcus granulosus proteasome prosome macropain subunit beta 0.005 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0057 0.0081 0.0098
Schistosoma mansoni caspase-7 (C14 family) 0.0215 0.0432 0.0524
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.01 0.0176 0.2162
Loa Loa (eye worm) hypothetical protein 0.0045 0.0053 0.0065
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0023 0.0023
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0024 0.0007 0.0008
Loa Loa (eye worm) calmodulin-like protein 0.0182 0.0358 0.0434
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0377 0.0793 0.2767
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0371 0.0778 0.0944
Loa Loa (eye worm) transcription factor SMAD2 0.0133 0.0249 0.0302
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.001 0.0013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.01 0.0176 0.1047
Brugia malayi Angiotensin-converting enzyme family protein 0.1226 0.2681 0.3251
Loa Loa (eye worm) hypothetical protein 0.0072 0.0113 0.0137
Trypanosoma cruzi cruzipain precursor, putative 0.0398 0.0839 0.1017
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0091 0.0091
Echinococcus multilocularis Polycystic kidney disease protein 0.0062 0.0091 0.0091
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0112 0.0202 0.0503
Schistosoma mansoni mitochondrial solute carrier 0.0182 0.0358 0.0434
Plasmodium falciparum serine repeat antigen 5 0.0327 0.0682 0.2379
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0142
Trypanosoma cruzi cysteine protease, putative 0.0725 0.1567 0.19
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0104 0.0127
Echinococcus multilocularis cathepsin L cysteine protease 0.1308 0.2865 0.2865
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Mycobacterium ulcerans hypothetical protein 0.0297 0.0616 0.3655
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.613
Toxoplasma gondii microneme protein MIC17B 0.0031 0.0023 0.0056
Echinococcus granulosus tissue type plasminogen activator 0.0048 0.006 0.006
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0024 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0044
Onchocerca volvulus 0.0193 0.0384 0.0929
Brugia malayi aspartic protease BmAsp-1, identical 0.0054 0.0074 0.009
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.01 0.0176 0.1047
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0023 0.0028
Trichomonas vaginalis histone deacetylase, putative 0.0125 0.0233 0.075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0027
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0022 0.0004 0.0004
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.0299 0.0362
Loa Loa (eye worm) hypothetical protein 0.0327 0.0682 0.0827
Toxoplasma gondii aldehyde dehydrogenase 0.0138 0.026 0.0647
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0037 0.0217
Echinococcus multilocularis chromatin regulatory protein sir2 0.0253 0.0517 0.0516
Onchocerca volvulus 0.0152 0.0291 0.0704
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0023 0.0056
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0138 0.026 0.0759
Giardia lamblia Cysteine protease 0.0327 0.0682 0.224
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0024 0.0007 0.0007
Trichomonas vaginalis histone deacetylase, putative 0.0125 0.0233 0.075
Onchocerca volvulus Cathepsin F homolog 0.1308 0.2865 0.6936
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0027
Giardia lamblia Cathepsin L precursor 0.0327 0.0682 0.224
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0013
Leishmania major cysteine peptidase A (CPA) 0.1308 0.2865 0.7126
Echinococcus granulosus neural cadherin 0.0025 0.0011 0.001
Giardia lamblia Alanyl dipeptidyl peptidase 0.0267 0.0548 0.1797
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0053 0.0064
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0024 0.0007 0.0006
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0193 0.0384 0.0466
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0162 0.0314 0.038
Trypanosoma brucei calmodulin, putative 0.0185 0.0365 0.09
Schistosoma mansoni hypothetical protein 0.01 0.0176 0.0214
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0023 0.0028
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0353
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0333 0.0695 0.1729
Plasmodium falciparum M17 leucyl aminopeptidase 0.0113 0.0205 0.0714
Echinococcus granulosus calpain 7 C02 family 0.1129 0.2464 0.2464
Echinococcus granulosus protein jagged 2 0.0025 0.0011 0.001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Plasmodium falciparum serine repeat antigen 6 0.0327 0.0682 0.2379
Brugia malayi transcriptional regulator, Sir2 family protein 0.0065 0.0099 0.0119
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0054 0.0074 0.0074
Entamoeba histolytica grainin, putative 0.0185 0.0365 0.1255
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0024 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0011 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0327 0.0682 0.224
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.0007 0.0021
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0097 0.0169 0.0205
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0064 0.0201
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0725 0.1567 0.3891
Trypanosoma brucei calmodulin, putative 0.0182 0.0358 0.0882
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0022 0.0004 0.0004
Brugia malayi histone deacetylase 1 (HD1) 0.0125 0.0233 0.0282
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0045 0.0053 0.0155
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3726 0.8244 1
Toxoplasma gondii histone deacetylase HDAC2 0.0125 0.0233 0.0579
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0053 0.0155
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0649 0.1399 0.3478
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.0007 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0024 0.0007 0.0008
Toxoplasma gondii peptidase, T1 family protein 0.0024 0.0007 0.0016
Onchocerca volvulus 0.0185 0.0365 0.0884
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0377 0.0793 0.2313
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0327 0.0682 0.2379
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0113 0.0205 0.0248
Onchocerca volvulus 0.0054 0.0074 0.0179
Echinococcus granulosus notch 0.0025 0.0011 0.001
Trypanosoma cruzi cruzipain precursor, putative 0.1418 0.3109 0.3771
Leishmania major hypothetical protein, conserved 0.0182 0.0358 0.089
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0024 0.0007 0.0008
Brugia malayi EGF-like domain containing protein 0.0025 0.0011 0.0013
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0725 0.1567 0.19
Echinococcus multilocularis calbindin 32 0.0185 0.0365 0.0365
Brugia malayi cathepsin B-like cysteine proteinase 0.3726 0.8244 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Echinococcus granulosus neurogenic locus protein delta 0.0025 0.0011 0.001
Echinococcus granulosus dnaJ subfamily B 0.044 0.0933 0.0933
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.01 0.0176 0.0176
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0091 0.0091
Plasmodium vivax hypothetical protein, conserved 0.0185 0.0365 0.1274
Plasmodium falciparum centrin-1 0.0182 0.0358 0.1249
Loa Loa (eye worm) calpain family protein 1 0.2211 0.4872 0.591
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0725 0.1567 0.5177
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.01 0.0176 0.043
Echinococcus multilocularis fat cadherin tumor suppressor 0.0025 0.0011 0.001
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0065 0.0099 0.0305
Echinococcus granulosus neuronal calcium sensor 0.0182 0.0358 0.0358
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0171 0.0171
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0377 0.0793 0.0961
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0253 0.0517 0.1692
Schistosoma mansoni calmodulin related calcium binding protein 0.0182 0.0358 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0111 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0682 0.224
Mycobacterium ulcerans Sir2-like regulatory protein 0.0065 0.0099 0.0584
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.613
Trypanosoma cruzi metacaspase, putative 0.0071 0.0111 0.0134
Leishmania major proteasome beta 5 subunit, putative 0.0164 0.0319 0.0792
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0098 0.0172 0.0208
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0113 0.0205 0.0248
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0023 0.0027
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.0007 0.0043
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.01 0.0176 0.1047
Leishmania major histone deacetylase, putative 0.0212 0.0426 0.1058
Onchocerca volvulus 0.0062 0.0091 0.022
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0649 0.1399 0.1696
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.028 0.0576 0.1891
Loa Loa (eye worm) hypothetical protein 0.0054 0.0074 0.009
Echinococcus granulosus histone deacetylase 8 0.0077 0.0126 0.0125
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.01 0.0176 0.0515
Schistosoma mansoni cathepsin F (C01 family) 0.1308 0.2865 0.3475
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0031 0.0023 0.0056
Loa Loa (eye worm) hypoxia-induced factor 1 0.0161 0.0312 0.0378
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0024 0.0007 0.0006
Schistosoma mansoni Mername-AA248 (C02 family) 0.1129 0.2464 0.2989
Toxoplasma gondii proteasome subunit 0.0024 0.0007 0.0016
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1308 0.2865 1
Trypanosoma brucei proteasome beta 6 subunit 0.0078 0.0127 0.0308
Entamoeba histolytica protein kinase, putative 0.0795 0.1723 0.6006
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0071 0.0111 0.0276
Trypanosoma brucei histone deacetylase, putative 0.0212 0.0426 0.105
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0037 0.0044
Entamoeba histolytica calcium-binding protein, putative 0.0182 0.0358 0.123
Loa Loa (eye worm) hypothetical protein 0.0072 0.0113 0.0137
Plasmodium vivax proteasome subunit beta type-3, putative 0.0024 0.0007 0.0022
Schistosoma mansoni z-protein (S1r protein) 0.0045 0.0053 0.0065
Loa Loa (eye worm) programmed cell death 8 0.01 0.0176 0.0214
Onchocerca volvulus 0.0037 0.0037 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Brugia malayi Cell death protein 3 precursor 0.0214 0.0431 0.0523
Entamoeba histolytica cysteine proteinase, putative 0.0725 0.1567 0.5459
Giardia lamblia Cathepsin L precursor 0.0327 0.0682 0.224
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Echinococcus granulosus tumor protein p63 0.039 0.0821 0.0821
Echinococcus multilocularis geminin 0.0177 0.0348 0.0348
Plasmodium vivax thioredoxin reductase, putative 0.1088 0.2375 0.8288
Echinococcus granulosus leucyl aminopeptidase 0.0022 0.0004 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1308 0.2865 0.2865
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0078 0.0127 0.0127
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.01 0.0176 0.1047
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Plasmodium falciparum proteasome subunit beta type-4 0.0024 0.0007 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.006 0.0073
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.01 0.0176 0.0439
Echinococcus multilocularis glycogen phosphorylase 0.0114 0.0208 0.0208
Leishmania major i/6 autoantigen-like protein 0.0182 0.0358 0.089
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0024 0.0007 0.0007
Mycobacterium tuberculosis Probable reductase 0.01 0.0176 0.0515
Trypanosoma brucei hypothetical protein 0.0333 0.0695 0.1721
Schistosoma mansoni sulfide quinone reductase 0.01 0.0176 0.0214
Echinococcus granulosus gamma secretase subunit aph 1 0.0265 0.0543 0.0542
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0267 0.0548 0.1895
Toxoplasma gondii EF hand domain-containing protein 0.0182 0.0358 0.089
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.0007 0.0043
Onchocerca volvulus Notchless protein homolog 0.0024 0.0007 0.0015
Trypanosoma cruzi Aph-1 protein, putative 0.0103 0.0183 0.0222
Schistosoma mansoni peroxidasin 0.0275 0.0566 0.0687
Brugia malayi Cadherin domain containing protein 0.0025 0.0011 0.0013
Echinococcus granulosus histone deacetylase 6 0.0212 0.0426 0.0426
Mycobacterium ulcerans leucyl aminopeptidase 0.0113 0.0205 0.1215
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.0007 0.0021
Brugia malayi hypothetical protein 0.0144 0.0274 0.0332
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3726 0.8244 1
Loa Loa (eye worm) animal heme peroxidase 0.0275 0.0566 0.0687
Brugia malayi Peroxidasin 0.0275 0.0566 0.0687
Echinococcus multilocularis EF hand domain containing family member A2 0.0182 0.0358 0.0358
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0171 0.0208
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0024 0.0007 0.0006
Brugia malayi proteasome subunit alpha type 1 0.0024 0.0007 0.0008
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0012 0.0029
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0164 0.0319 0.093
Schistosoma mansoni hypothetical protein 0.0062 0.0091 0.011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0327 0.0682 0.0827
Echinococcus granulosus calmodulin 0.0182 0.0358 0.0358
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0023 0.0028
Trypanosoma cruzi histone deacetylase, putative 0.0212 0.0426 0.0516
Plasmodium vivax unspecified product 0.0398 0.0839 0.2928
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.0007 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0327 0.0682 0.224
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0027
Schistosoma mansoni loxhd1 0.0062 0.0091 0.011
Echinococcus granulosus flap endonuclease 1 0.0026 0.0012 0.0012
Echinococcus granulosus neurocalcin 0.0182 0.0358 0.0358
Trypanosoma brucei calpain-like protein, putative 0.1129 0.2464 0.6126
Schistosoma mansoni calpain-7 (C02 family) 0.1132 0.2472 0.2998
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0024 0.0007 0.0022
Echinococcus multilocularis histone deacetylase 1 0.0125 0.0233 0.0233
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0037 0.0107
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.001 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0327 0.0682 0.224
Schistosoma mansoni rab 0.0182 0.0358 0.0434
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.0299 0.0362
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0104 0.0127
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0277 0.057 0.0691
Schistosoma mansoni coup transcription factor 0.0031 0.0023 0.0028
Onchocerca volvulus 0.1308 0.2865 0.6936
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0037 0.01
Leishmania major hypothetical protein, conserved 0.0048 0.006 0.015
Brugia malayi calpain 5 0.0333 0.0695 0.0843
Echinococcus granulosus caspase 3 0.0144 0.0275 0.0275
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0333 0.0695 0.0843
Echinococcus granulosus histone deacetylase 7 0.0212 0.0426 0.0426
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0037 0.0044
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0078 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0063 0.0094 0.0114
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0023 0.0023
Onchocerca volvulus 0.0275 0.0566 0.137
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0053 0.0065
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0182 0.0358 0.0358
Brugia malayi Cathepsin L-like precursor 0.0911 0.198 0.2401
Mycobacterium tuberculosis Conserved protein 0.0037 0.0037 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0327 0.0682 0.2379
Plasmodium falciparum plasmepsin III 0.0054 0.0074 0.0258
Loa Loa (eye worm) hypothetical protein 0.0152 0.0291 0.0353
Brugia malayi hypoxia-induced factor 1 0.0161 0.0312 0.0378
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0024 0.0007 0.0006
Echinococcus multilocularis Transglutaminase 0.0297 0.0616 0.0615
Echinococcus multilocularis cysteine protease 0.1308 0.2865 0.2865
Schistosoma mansoni notch 0.0025 0.0011 0.0013
Toxoplasma gondii prolyl endopeptidase 0.1828 0.402 1
Echinococcus multilocularis notch 0.0025 0.0011 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.001 0.006
Brugia malayi Animal haem peroxidase family protein 0.0275 0.0566 0.0687
Brugia malayi hypothetical protein 0.0275 0.0566 0.0687
Mycobacterium leprae probable zinc metalloprotease 0.0097 0.0169 0.1006
Echinococcus multilocularis glycogen phosphorylase 0.0114 0.0208 0.0208
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.001 0.006
Trypanosoma brucei proteasome alpha 7 subunit 0.0024 0.0007 0.0007
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0024 0.0007 0.0022
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.0007 0.0021
Echinococcus granulosus cpg binding protein 0.0033 0.0027 0.0026
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0267 0.0548 0.1895
Onchocerca volvulus 0.0025 0.0011 0.0025
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.028 0.0576 0.1891
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0024 0.0007 0.0016
Brugia malayi nuclear receptor NHR-88 0.0031 0.0023 0.0028
Onchocerca volvulus 0.1308 0.2865 0.6936
Brugia malayi Animal haem peroxidase family protein 0.0275 0.0566 0.0687
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0112 0.0202 0.0202
Schistosoma mansoni ap endonuclease 0.0039 0.004 0.0048
Loa Loa (eye worm) hypothetical protein 0.1877 0.413 0.501
Echinococcus multilocularis slit 2 protein 0.0025 0.0011 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Entamoeba histolytica hypothetical protein 0.0327 0.0682 0.2362
Trichomonas vaginalis disulfide oxidoreductase, putative 0.01 0.0176 0.0564
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0053 0.0064
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0253 0.0517 0.0626
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0327 0.0682 0.2379
Trypanosoma brucei SIR2-like protein 4, putative 0.0065 0.0099 0.0236
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0182 0.0358 0.0434
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.0961
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0164 0.0319 0.0386
Schistosoma mansoni hypothetical protein 0.0152 0.0291 0.0353
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0142
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Leishmania major calmodulin, putative 0.0182 0.0358 0.089
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0024 0.0007 0.0022
Echinococcus multilocularis acylamino acid releasing enzyme 0.0267 0.0548 0.0548
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.01 0.0176 0.0176
Onchocerca volvulus Slit protein homolog 0.0025 0.0011 0.0025
Echinococcus granulosus calpain 5 0.1129 0.2464 0.2464
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0182 0.0358 0.1249
Echinococcus granulosus slit 2 protein 0.0025 0.0011 0.001
Onchocerca volvulus 0.1308 0.2865 0.6936
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0104 0.0127
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0022 0.0004 0.0004
Entamoeba histolytica grainin 2 0.0185 0.0366 0.1259
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0037 0.0217
Brugia malayi Animal haem peroxidase family protein 0.0275 0.0566 0.0687
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0024 0.0007 0.0008
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0358 0.0434
Echinococcus granulosus EF HAND 1 calcium binding site 0.0182 0.0358 0.0358
Schistosoma mansoni ap endonuclease 0.0039 0.004 0.0048
Loa Loa (eye worm) hypothetical protein 0.0376 0.0791 0.0959
Brugia malayi EF hand family protein 0.0185 0.0365 0.0443
Schistosoma mansoni aldehyde dehydrogenase 0.0138 0.026 0.0316
Schistosoma mansoni cell polarity protein 0.0025 0.0011 0.0013
Plasmodium falciparum plasmepsin I 0.0054 0.0074 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0053 0.0155
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0081 0.0098
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0022 0.0004 0.0004
Trypanosoma cruzi calmodulin, putative 0.0182 0.0358 0.0434
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0327 0.0682 0.224
Brugia malayi Peptidase family M13 containing protein 0.0097 0.0169 0.0205
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1021 0.2225 0.2699
Brugia malayi regulator of G-protein signaling egl-10 0.0045 0.0053 0.0065
Toxoplasma gondii hypothetical protein 0.0031 0.0023 0.0056
Onchocerca volvulus Chorion peroxidase homolog 0.0275 0.0566 0.137
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Schistosoma mansoni memapsin-2 (A01 family) 0.0521 0.1112 0.1349
Brugia malayi prolyl oligopeptidase family protein 0.0267 0.0548 0.0665
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0024 0.0007 0.0008
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0277 0.057 0.0691
Loa Loa (eye worm) hypothetical protein 0.0054 0.0074 0.009
Schistosoma mansoni cytochrome P450 0.0024 0.0007 0.0009
Schistosoma mansoni sulfide quinone reductase 0.01 0.0176 0.0214
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0066 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0358 0.1166
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0911 0.198 0.2401
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Giardia lamblia Cathepsin L-like protease 0.0327 0.0682 0.224
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0327 0.0682 0.0827
Plasmodium falciparum histone deacetylase 1 0.0125 0.0233 0.0812
Echinococcus granulosus apoptotic protease activating factor 1 0.0144 0.0274 0.0274
Entamoeba histolytica glutamate synthase beta subunit, putative 0.01 0.0176 0.0595
Trichomonas vaginalis disulfide oxidoreductase, putative 0.01 0.0176 0.0564
Toxoplasma gondii NADPH-glutathione reductase 0.0377 0.0793 0.1972
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Schistosoma mansoni calmodulin 0.0182 0.0358 0.0434
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0053 0.0065
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.613
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0006 0.0008
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0291
Echinococcus multilocularis cathepsin b 0.3726 0.8244 0.8244
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0377 0.0793 0.0961
Giardia lamblia Thymus-specific serine protease precursor 0.0063 0.0094 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0053 0.0065
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1828 0.402 0.4877
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0377 0.0793 0.0961
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0065 0.0099 0.0098
Leishmania major proteasome alpha 2 subunit, putative 0.0024 0.0007 0.0016
Trypanosoma brucei calpain, putative 0.0333 0.0695 0.1721
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0098 0.0172 0.0209
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.01 0.0176 0.0616
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.001 0.0029
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0024 0.0007 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0037 0.0044
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0327 0.0682 0.2379
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0011 0.001
Leishmania major protein kinase, putative 0.0182 0.0358 0.089
Mycobacterium ulcerans NADH dehydrogenase 0.01 0.0176 0.1047
Mycobacterium ulcerans lipase LipD 0.0037 0.0037 0.0217
Chlamydia trachomatis glycogen phosphorylase 0.0114 0.0208 0.2628
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0072 0.0113 0.0137
Trypanosoma brucei hypothetical protein, conserved 0.0182 0.0358 0.0882
Onchocerca volvulus Dual oxidase homolog 0.0275 0.0566 0.137
Echinococcus multilocularis protein jagged 2 0.0025 0.0011 0.001
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0253 0.0517 0.1277
Plasmodium falciparum thioredoxin reductase 0.1088 0.2375 0.8288
Onchocerca volvulus 0.0031 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0012
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0037 0.0037
Schistosoma mansoni flap endonuclease-1 0.0023 0.0006 0.0007
Toxoplasma gondii microneme protein, putative 0.0031 0.0023 0.0056
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.001 0.0012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0333 0.0695 0.0843
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0327 0.0682 0.224
Schistosoma mansoni cathepsin C 0.0327 0.0682 0.0827
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0024 0.0007 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3726 0.8244 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0023 0.0028
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0327 0.0682 0.2379
Treponema pallidum thioredoxin reductase (trxB) 0.01 0.0176 0.1815
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0111 0.0346
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0024 0.0007 0.0019
Brugia malayi prolyl oligopeptidase family protein 0.0267 0.0548 0.0665
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Loa Loa (eye worm) ctsf protein 0.1308 0.2865 0.3475
Echinococcus multilocularis protein jagged 1 0.0025 0.0011 0.001
Leishmania major hypothetical protein, conserved 0.01 0.0176 0.0439
Trypanosoma cruzi trypanothione reductase, putative 0.0377 0.0793 0.0961
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0053 0.0064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0024 0.0007 0.0022
Mycobacterium tuberculosis Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0142 0.027 0.0787
Trichomonas vaginalis glycogen phosphorylase, putative 0.0114 0.0208 0.067
Mycobacterium leprae Probable lipase LipE 0.0037 0.0037 0.0217
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0104 0.0127
Toxoplasma gondii proteasome subunit beta type 2, putative 0.005 0.0066 0.0164
Schistosoma mansoni cathepsin F (C01 family) 0.1308 0.2865 0.3475
Onchocerca volvulus 0.1877 0.413 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0011 0.0013
Trypanosoma brucei Calpain-like protein 1.2 0.0333 0.0695 0.1721
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0094 0.0163 0.0163
Leishmania major cathepsin L-like protease 0.1308 0.2865 0.7126
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Brugia malayi aspartic protease BmAsp-2, identical 0.0054 0.0074 0.009
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0012 0.0017
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0333 0.0695 0.0843
Giardia lamblia Hypothetical protein 0.0327 0.0682 0.224
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0024 0.0007 0.0008
Giardia lamblia Cathepsin B precursor 0.1378 0.3021 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0152 0.0291 0.0291
Giardia lamblia Cathepsin L precursor 0.0327 0.0682 0.224
Loa Loa (eye worm) RNA binding protein 0.0068 0.0104 0.0127
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Schistosoma mansoni hypothetical protein 0.0177 0.0348 0.0422
Loa Loa (eye worm) EF hand family protein 0.0182 0.0358 0.0434
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0027
Schistosoma mansoni cathepsin D (A01 family) 0.0338 0.0706 0.0857
Schistosoma mansoni alcohol dehydrogenase 0.0162 0.0314 0.038
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0037 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.0152 0.0291 0.0353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0023 0.0028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Mycobacterium leprae Conserved hypothetical protein 0.0297 0.0616 0.3655
Loa Loa (eye worm) PXA domain-containing protein 0.0045 0.0053 0.0065
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1129 0.2464 0.2989
Plasmodium vivax NAD-dependent deacetylase, putative 0.0065 0.0099 0.0343
Giardia lamblia Encystation-specific protease 0.0327 0.0682 0.224
Trypanosoma brucei Calpain-like protein 2 0.0333 0.0695 0.1721
Trypanosoma brucei caltractin, putative 0.0185 0.0366 0.0903
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0012 0.0014
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0125 0.0233 0.075
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0112 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0371 0.0778 0.0944
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0353
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0024 0.0007 0.0007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.2989
Echinococcus granulosus Regulator of G protein signaling 20 0.0045 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus multilocularis prolyl endopeptidase 0.1828 0.402 0.402
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0048 0.006 0.021
Echinococcus granulosus geminin 0.0177 0.0348 0.0348
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.01 0.0176 0.0515
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.0007 0.0021
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0177 0.0348 0.0422
Plasmodium falciparum serine repeat antigen 3 0.0327 0.0682 0.2379
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0099 0.0343
Echinococcus multilocularis inhibitor of apoptosis protein 0.0193 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0327 0.0682 0.0827
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0024 0.0007 0.0022
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.001 0.0025
Mycobacterium ulcerans hypothetical protein 0.0152 0.0291 0.1727
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0725 0.1567 0.3891
Toxoplasma gondii histone deacetylase HDAC5 0.0077 0.0126 0.0314
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0024 0.0007 0.0006
Loa Loa (eye worm) notch protein 0.0025 0.0011 0.0013
Brugia malayi Kringle domain containing protein 0.0048 0.006 0.0073
Plasmodium falciparum plasmepsin II 0.0054 0.0074 0.0258
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0063 0.0094 0.0114
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0054 0.0074 0.0074
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.0007 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0098 0.0172 0.0172
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.004 0.0048
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0024 0.0007 0.0008
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0377 0.0793 0.2313
Giardia lamblia Transcriptional regulator, Sir2 family 0.0065 0.0099 0.0305
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0165 0.032 0.0388
Echinococcus multilocularis proteasome subunit alpha type 2 0.0024 0.0007 0.0006
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0024 0.0007 0.0008
Brugia malayi beta-lactamase family protein 0.0037 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0063 0.0094 0.0114
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0023 0.0023
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0047 0.0133
Leishmania major cathepsin L-like protease 0.1418 0.3109 0.7734
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0037 0.0107
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0078 0.0127 0.0154
Echinococcus multilocularis Glycosyl transferase, family 35 0.0114 0.0208 0.0208
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0053 0.0053
Treponema pallidum NADH oxidase 0.0377 0.0793 1
Echinococcus multilocularis hypothetical protein 0.1129 0.2464 0.2464
Echinococcus granulosus acylamino acid releasing enzyme 0.0267 0.0548 0.0548
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.2989
Leishmania major cathepsin L-like protease 0.1418 0.3109 0.7734
Schistosoma mansoni notch 0.0026 0.0011 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0104 0.0127
Entamoeba histolytica cysteine protease, putative 0.0327 0.0682 0.2362
Schistosoma mansoni disulfide oxidoreductase 0.01 0.0176 0.0214
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.01 0.0176 0.0439
Trypanosoma cruzi histone deacetylase 1, putative 0.0125 0.0233 0.0282
Loa Loa (eye worm) hypothetical protein 0.0215 0.0432 0.0524
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0142
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0164 0.0319 0.1892
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0253 0.0517 0.0516
Plasmodium vivax vivapain-2 0.1308 0.2865 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1308 0.2865 0.2865
Brugia malayi EGF-like domain containing protein 0.0025 0.0011 0.0013
Mycobacterium ulcerans glutamate synthase subunit beta 0.01 0.0176 0.1047
Schistosoma mansoni hypothetical protein 0.0094 0.0162 0.0196
Trichomonas vaginalis calmodulin, putative 0.0182 0.0358 0.1166
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.01 0.0176 0.0214
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0055 0.0055
Entamoeba histolytica glutamate synthase beta subunit, putative 0.01 0.0176 0.0595
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3726 0.8244 1
Trypanosoma brucei calpain, putative 0.0333 0.0695 0.1721
Echinococcus granulosus microtubule associated protein 2 0.1593 0.3498 0.3498
Entamoeba histolytica cysteine protease, putative 0.0327 0.0682 0.2362
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Giardia lamblia Hypothetical protein 0.0327 0.0682 0.224
Onchocerca volvulus 0.0037 0.0037 0.0089
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0054 0.0074 0.0184
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0053 0.0053
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0377 0.0793 0.4707
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0024 0.0007 0.0008
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0327 0.0682 0.2379
Echinococcus granulosus neurogenic locus notch protein 4 0.0025 0.0011 0.001
Plasmodium falciparum serine repeat antigen 9 0.0327 0.0682 0.2379
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0024 0.0007 0.0022
Brugia malayi GCC2 and GCC3 family protein 0.0025 0.0011 0.0013
Giardia lamblia Cathepsin L precursor 0.0327 0.0682 0.224
Brugia malayi Trypsin-like protease protein 5 0.0152 0.0291 0.0353
Echinococcus granulosus cathepsin L cysteine proteinase 0.1308 0.2865 0.2865
Chlamydia trachomatis cytosol aminopeptidase 0.0113 0.0205 0.2582
Toxoplasma gondii histone deacetylase HDAC3 0.0125 0.0233 0.0579
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0327 0.0682 0.0827
Echinococcus multilocularis calpain 7 (C02 family) 0.1129 0.2464 0.2464
Loa Loa (eye worm) hypothetical protein 0.0144 0.0274 0.0332
Mycobacterium ulcerans hypothetical protein 0.0037 0.0037 0.0217
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.01 0.0176 0.0595
Echinococcus multilocularis calpain A 0.3191 0.7052 0.7052
Trypanosoma brucei metacaspase MCA3 0.0071 0.0111 0.0267
Loa Loa (eye worm) hypothetical protein 0.01 0.0176 0.0214
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.1177 0.2571 0.3119
Loa Loa (eye worm) hypothetical protein 0.0072 0.0113 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0182 0.0358 0.0434
Brugia malayi Thioredoxin family protein 0.0297 0.0616 0.0747
Mycobacterium ulcerans hypothetical protein 0.0025 0.001 0.006
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.01 0.0176 0.0515
Trypanosoma brucei mitochondrial calcium uptake 1 0.0182 0.0358 0.0882
Giardia lamblia Alanyl dipeptidyl peptidase 0.0267 0.0548 0.1797
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.0007 0.0043
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0182 0.0358 0.123
Brugia malayi proteasome subunit alpha type 6 0.0024 0.0007 0.0008
Leishmania major centrin, putative 0.0182 0.0358 0.089
Echinococcus multilocularis cathepsin L 0.0327 0.0682 0.0682
Trypanosoma cruzi histone deacetylase, putative 0.0212 0.0426 0.0516
Brugia malayi cytosol aminopeptidase 0.0022 0.0004 0.0004
Echinococcus multilocularis RUN 0.0062 0.0091 0.0091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.004 0.0048
Trypanosoma brucei cysteine peptidase, putative 0.0333 0.0695 0.1721
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0065 0.0099 0.0322
Trypanosoma brucei centrin-3 0.0185 0.0366 0.0903
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0055 0.0137
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0098 0.0172 0.0428
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Echinococcus multilocularis centrin 2 0.0182 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0098 0.0172 0.0209
Loa Loa (eye worm) hypothetical protein 0.0333 0.0695 0.0843
Loa Loa (eye worm) cathepsin B 0.1378 0.3021 0.3664
Trypanosoma cruzi oligopeptidase b 0.0778 0.1684 0.2042
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0023 0.0027
Brugia malayi Cadherin domain containing protein 0.0025 0.0011 0.0013
Brugia malayi nuclear hormone receptor 0.0031 0.0023 0.0028
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0053 0.0053
Toxoplasma gondii preprocathepsin c precursor, putative 0.0327 0.0682 0.1696
Brugia malayi Delta serrate ligand family protein 0.0025 0.0011 0.0013
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0023 0.0023
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.004 0.0099
Brugia malayi hypothetical protein 0.0174 0.0342 0.0414
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0333 0.0695 0.0843
Schistosoma mansoni calpain (C02 family) 0.1129 0.2464 0.2989
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Loa Loa (eye worm) hypothetical protein 0.0273 0.0562 0.0681
Loa Loa (eye worm) hypothetical protein 0.0189 0.0375 0.0455
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.01 0.0176 0.1047
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.01 0.0176 0.2162
Leishmania major metacaspase, putative 0.0071 0.0111 0.0276
Onchocerca volvulus 0.0031 0.0023 0.0055
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Leishmania major kinesin, putative 0.0795 0.1723 0.4286
Echinococcus granulosus histone deacetylase 3 0.0125 0.0233 0.0233
Schistosoma mansoni cathepsin F (C01 family) 0.0911 0.198 0.2401
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0358 0.0434
Plasmodium vivax proteasome subunit beta type-2, putative 0.005 0.0066 0.0229
Trypanosoma brucei I/6 autoantigen 0.0182 0.0358 0.0882
Toxoplasma gondii histone deacetylase SIR2 0.0065 0.0099 0.0245
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.028 0.0576 0.1891
Giardia lamblia Cathepsin L precursor 0.0327 0.0682 0.224
Brugia malayi proteasome subunit alpha type 3 0.0024 0.0007 0.0008
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0182 0.0358 0.0434
Schistosoma mansoni cathepsin s 0.0398 0.0839 0.1017
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.001 0.006
Plasmodium falciparum LCCL domain-containing protein 0.0062 0.0091 0.0317
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.01 0.0176 0.0564
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0023 0.0028
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0327 0.0682 0.224
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0024 0.0007 0.0022
Trichomonas vaginalis peptide N-glycanase, putative 0.0297 0.0616 0.2021
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0012 0.0012
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0296 0.0612 0.3632
Brugia malayi Cathepsin L-like precursor 0.1308 0.2865 0.3475
Plasmodium vivax vivapain-3 0.0725 0.1567 0.5469
Mycobacterium tuberculosis Probable dehydrogenase 0.01 0.0176 0.0515
Loa Loa (eye worm) prolyl oligopeptidase 0.0267 0.0548 0.0665
Loa Loa (eye worm) hypothetical protein 0.0193 0.0384 0.0466
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0023 0.0028
Brugia malayi PAS domain containing protein 0.0052 0.007 0.0084
Trichomonas vaginalis calcineurin B subunit, putative 0.0185 0.0365 0.119
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Plasmodium falciparum histone deacetylase, putative 0.0212 0.0426 0.1485
Schistosoma mansoni glutamate synthase 0.01 0.0176 0.0214
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0171 0.0208
Entamoeba histolytica cysteine proteinase, putative 0.0911 0.198 0.6904
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.004 0.0048
Onchocerca volvulus 0.0063 0.0094 0.0228
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0267 0.0548 0.0665
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0024 0.0007 0.0008
Giardia lamblia Histone deacetylase 0.0125 0.0233 0.075
Echinococcus granulosus survival motor neuron protein 1 0.0522 0.1116 0.1116
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0037 0.0082
Schistosoma mansoni lipoxygenase 0.0258 0.0527 0.0639
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0024 0.0007 0.0008
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0182 0.0358 0.0358
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.0007 0.0021
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Schistosoma mansoni histone deacetylase hda2 0.0077 0.0126 0.0152
Leishmania major cathepsin L-like protease 0.1418 0.3109 0.7734
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0267 0.0548 0.0665
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0267 0.0548 0.1363
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0053 0.0065
Brugia malayi Cathepsin L-like precursor 0.0398 0.0839 0.1017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0023 0.0028
Brugia malayi Papain family cysteine protease containing protein 0.0327 0.0682 0.0827
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0649 0.1399 0.1696
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0006 0.0008
Leishmania major centrin, putative 0.0182 0.0358 0.089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.0961
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Echinococcus granulosus cathepsin L 0.0725 0.1567 0.1567
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0327 0.0682 0.224
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0023 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0682 0.224
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0353
Loa Loa (eye worm) hypothetical protein 0.2211 0.4872 0.591
Loa Loa (eye worm) TK/ROR protein kinase 0.0048 0.006 0.0073
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Brugia malayi Flap endonuclease-1 0.0026 0.0012 0.0014
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0065 0.0099 0.0119
Trypanosoma brucei kinesin, putative 0.0795 0.1723 0.4281
Schistosoma mansoni reticulocalbin 0.0185 0.0365 0.0443
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0023 0.0028
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0162 0.0314 0.078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Brugia malayi Pepsin A precursor 0.0054 0.0074 0.009
Schistosoma mansoni microtubule-associated protein tau 0.1593 0.3498 0.4243
Brugia malayi hypothetical protein 0.0045 0.0053 0.0065
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0125 0.0233 0.075
Trypanosoma brucei antigen, putative 0.1129 0.2464 0.6126
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.0007 0.0021
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0024 0.0007 0.0008
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Chlamydia trachomatis thioredoxin reductase 0.01 0.0176 0.2225
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0778 0.1684 0.4188
Brugia malayi cathepsin Z-like cysteine proteinase 0.0327 0.0682 0.0827
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0078 0.0127 0.0154
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0377 0.0793 0.2767
Trypanosoma brucei prolyl oligopeptidase, putative 0.0778 0.1684 0.4183
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0649 0.1399 0.1398
Trypanosoma brucei histone deacetylase 2 0.0077 0.0126 0.0303
Loa Loa (eye worm) hypothetical protein 0.0522 0.1116 0.1354
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.01 0.0176 0.0214
Plasmodium falciparum plasmepsin VI 0.0054 0.0074 0.0258
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0047 0.0163
Echinococcus multilocularis histone deacetylase 3 0.0125 0.0233 0.0233
Trypanosoma brucei Component of motile flagella 41 0.0182 0.0358 0.0882
Echinococcus granulosus EF hand domain containing family member A2 0.0185 0.0365 0.0365
Onchocerca volvulus 0.1308 0.2865 0.6936
Trichomonas vaginalis glutamate synthase, putative 0.01 0.0176 0.0564
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0024 0.0007 0.0008
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0012
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0024 0.0007 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0053 0.0155
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0024 0.0007 0.0006
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0327 0.0682 0.2379
Schistosoma mansoni neprilysin-2 (M13 family) 0.0049 0.0063 0.0076
Brugia malayi Proteasome subunit alpha type 1 0.0024 0.0007 0.0008
Giardia lamblia Hypothetical protein 0.0185 0.0365 0.119
Toxoplasma gondii leucyl aminopeptidase LAP 0.0113 0.0205 0.0509
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.0007 0.0018
Plasmodium vivax histone deacetylase, putative 0.0212 0.0426 0.1485
Trichomonas vaginalis histone deacetylase, putative 0.0125 0.0233 0.075
Schistosoma mansoni centrin 0.0182 0.0358 0.0434
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.0299 0.0298
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.01 0.0176 0.0214
Loa Loa (eye worm) animal heme peroxidase 0.0275 0.0566 0.0687
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.0007 0.0007
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0023 0.0056
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0053 0.0053
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.0007 0.0043
Entamoeba histolytica calmodulin, putative 0.0182 0.0358 0.123
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0049 0.0064 0.0379
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.0007 0.0021
Giardia lamblia High cysteine protein 0.0025 0.0011 0.0013
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0094 0.0162 0.0196
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3188 0.7045 0.8546
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0066 0.0197
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0104 0.0127
Loa Loa (eye worm) hypothetical protein 0.2673 0.59 0.7157
Loa Loa (eye worm) thioredoxin reductase 0.1088 0.2375 0.288
Echinococcus granulosus tar DNA binding protein 0.0068 0.0104 0.0104
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0327 0.0682 0.0827
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0333 0.0695 0.2285
Schistosoma mansoni notch 0.0025 0.0011 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0377 0.0793 0.0961
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1129 0.2464 0.2989
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0024 0.0007 0.0008
Entamoeba histolytica glycogenphosphorylase, putative 0.0049 0.0064 0.0201
Plasmodium vivax proteasome subunit beta type-4, putative 0.0024 0.0007 0.0022
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0098 0.0172 0.0172
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.01 0.0176 0.0176
Loa Loa (eye worm) glycogen phosphorylase 0.0114 0.0208 0.0253
Loa Loa (eye worm) histone deacetylase 11 0.0077 0.0126 0.0152
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0012 0.0018
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0377 0.0793 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.0291 0.0353
Brugia malayi Serine protease Z688.6 precursor 0.0063 0.0094 0.0114
Brugia malayi Trypsin family protein 0.0152 0.0291 0.0353
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0024 0.0007 0.0007
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0037 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Brugia malayi Papain family cysteine protease containing protein 0.1308 0.2865 0.3475
Entamoeba histolytica prolyl oligopeptidase family protein 0.0267 0.0548 0.1895
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0377 0.0793 0.1971
Toxoplasma gondii PAN/Apple domain-containing protein 0.0031 0.0023 0.0056
Onchocerca volvulus 0.0275 0.0566 0.137
Echinococcus granulosus caspase 2 0.0214 0.0431 0.0431
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0024 0.0007 0.0008
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0333 0.0695 0.2285
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0044
Plasmodium vivax serine-repeat antigen (SERA) 0.0327 0.0682 0.2379
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0333 0.0695 0.2285
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0171 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0327 0.0682 0.224
Toxoplasma gondii aspartyl protease ASP1 0.0054 0.0074 0.0184
Onchocerca volvulus 0.0152 0.0291 0.0704
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Onchocerca volvulus 0.0031 0.0023 0.0054
Brugia malayi Papain family cysteine protease containing protein 0.0327 0.0682 0.0827
Brugia malayi glutamate synthase 0.01 0.0176 0.0214
Echinococcus multilocularis cathepsin L cysteine protease 0.1308 0.2865 0.2865
Leishmania major hypothetical protein, unknown function 0.0333 0.0695 0.1729
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0333 0.0695 0.0843
Trypanosoma cruzi trypanothione reductase, putative 0.1088 0.2375 0.288
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0063 0.0094 0.0235
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Brugia malayi prolyl oligopeptidase family protein 0.1021 0.2225 0.2699
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0024 0.0007 0.0006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0065 0.0099 0.0305
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0182 0.0358 0.1166
Brugia malayi beta-lactamase family protein 0.0037 0.0037 0.0044
Leishmania major calmodulin-like protein 0.0182 0.0358 0.089
Loa Loa (eye worm) hypothetical protein 0.0152 0.0291 0.0353
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1721
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0012 0.0029
Schistosoma mansoni calmodulin 0.0182 0.0358 0.0434
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0022 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0911 0.198 0.2401
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0162 0.0314 0.1863
Loa Loa (eye worm) hypothetical protein 0.0062 0.0091 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0023 0.0028
Echinococcus granulosus calpain 0.1129 0.2464 0.2464
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0065 0.0099 0.0343
Giardia lamblia Cysteine protease 0.0327 0.0682 0.224
Plasmodium falciparum serine repeat antigen 4 0.0327 0.0682 0.2379
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0094 0.0292
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.0007 0.0043
Entamoeba histolytica hypothetical protein 0.0045 0.0053 0.0164
Brugia malayi histone deacetylase 3 (HD3) 0.0125 0.0233 0.0282
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.0063 0.0076
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Schistosoma mansoni hypothetical protein 0.0152 0.0291 0.0353
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0333 0.0695 0.1721
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.2989
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Onchocerca volvulus 0.0031 0.0023 0.0055
Trypanosoma brucei cysteine peptidase C (CPC) 0.1378 0.3021 0.7511
Brugia malayi steroid hormone receptor 0.0031 0.0023 0.0028
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0037 0.0044
Schistosoma mansoni hypothetical protein 0.0107 0.0191 0.0231
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Brugia malayi prolyl oligopeptidase family protein 0.1828 0.402 0.4877
Brugia malayi Papain family cysteine protease containing protein 0.0725 0.1567 0.19
Mycobacterium ulcerans NAD-dependent deacetylase 0.0065 0.0099 0.0584
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0778 0.1684 0.4915
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0011 0.001
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0024 0.0007 0.0008
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.0007 0.0043
Entamoeba histolytica hypothetical protein 0.0045 0.0053 0.0164
Trichomonas vaginalis calmodulin, putative 0.0182 0.0358 0.1166
Plasmodium falciparum metacaspase 1 0.0071 0.0111 0.0387
Echinococcus multilocularis calmodulin 0.0182 0.0358 0.0358
Brugia malayi regulator of G-protein signaling rgs-7 0.0045 0.0053 0.0065
Onchocerca volvulus 0.0152 0.0291 0.0704
Toxoplasma gondii thioredoxin reductase 0.1088 0.2375 0.5906
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Giardia lamblia Cathepsin B precursor 0.1378 0.3021 1
Echinococcus granulosus expressed protein 0.0871 0.1892 0.1892
Echinococcus granulosus cathepsin b 0.3726 0.8244 0.8244
Loa Loa (eye worm) peptidase family M13 containing protein 0.0072 0.0113 0.0137
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0253 0.0517 0.0626
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.01 0.0176 0.0439
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.01 0.0176 0.1047
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0107 0.0191 0.0231
Schistosoma mansoni notch 0.0025 0.0011 0.0013
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0098 0.0172 0.0208
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0024 0.0007 0.0016
Brugia malayi cathepsin L-like precursor 0.0911 0.198 0.2401
Mycobacterium ulcerans zinc metalloprotease 0.0097 0.0169 0.1006
Onchocerca volvulus Cathepsin L homolog 0.0327 0.0682 0.165
Trypanosoma cruzi metacaspase 5, putative 0.0071 0.0111 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.0682 0.224
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0327 0.0682 0.2379
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0094 0.0162 0.0162
Trypanosoma cruzi histone deacetylase 1, putative 0.0125 0.0233 0.0282
Trichomonas vaginalis calpain, putative 0.0333 0.0695 0.2285
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0097 0.0169 0.0494
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0063 0.0094 0.0114
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.0025 0.003
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.01 0.0176 0.1047
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Leishmania major proteasome beta 3 subunit, putative 0.0024 0.0007 0.0016
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1308 0.2865 0.3475
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Loa Loa (eye worm) histone deacetylase 7A 0.0212 0.0426 0.0516
Brugia malayi hypothetical protein 0.0522 0.1116 0.1354
Trypanosoma cruzi Aph-1 protein, putative 0.0103 0.0183 0.0222
Onchocerca volvulus 0.0025 0.0011 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1721
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0164 0.0319 0.0386
Trichomonas vaginalis calmodulin, putative 0.0182 0.0358 0.1166
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0025 0.0011 0.0013
Trichomonas vaginalis disulfide oxidoreductase, putative 0.01 0.0176 0.0564
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0111 0.0346
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0004 0.0004
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0353
Echinococcus granulosus cathepsin l cysteine peptidase 0.1308 0.2865 0.2865
Schistosoma mansoni calpain-2 (C02 family) 0.0333 0.0695 0.0843
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0012 0.0014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0053 0.0313
Loa Loa (eye worm) hypothetical protein 0.0045 0.0053 0.0065
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0377 0.0793 0.4707
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0024 0.0007 0.0008
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.01 0.0176 0.1047
Echinococcus granulosus calpain A 0.1129 0.2464 0.2464
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0053 0.0065
Loa Loa (eye worm) hypothetical protein 0.0048 0.006 0.0073
Echinococcus multilocularis gamma secretase subunit aph 1 0.0265 0.0543 0.0542
Loa Loa (eye worm) hypothetical protein 0.028 0.0576 0.0699
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0023 0.0027
Schistosoma mansoni glycogen phosphorylase 0.0114 0.0208 0.0253
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.004 0.009
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0025 0.0011 0.0013
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0182 0.0358 0.123
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0065 0.0099 0.0305
Echinococcus multilocularis histone deacetylase 0.0212 0.0426 0.0426
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0024 0.0007 0.0007
Schistosoma mansoni lipoxygenase 0.0369 0.0774 0.0939
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0024 0.0007 0.0006
Schistosoma mansoni chromatin regulatory protein sir2 0.0065 0.0099 0.0119
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0113 0.0205 0.0509
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.0007 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0053 0.0155
Leishmania major hypothetical protein, conserved 0.0037 0.0037 0.0091
Leishmania major proteasome beta 7 subunit, putative 0.0024 0.0007 0.0016
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1021 0.2224 0.2698
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.0961
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0377 0.0793 0.2767
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0037 0.0107
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Giardia lamblia Serine peptidase, putative 0.0063 0.0094 0.0292
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.0007 0.0043
Entamoeba histolytica cysteine proteinase, putative 0.0725 0.1567 0.5459
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.0007 0.0043
Trypanosoma cruzi metacaspase, putative 0.0071 0.0111 0.0134
Entamoeba histolytica cysteine protease, putative 0.1308 0.2865 1
Schistosoma mansoni survival motor neuron protein 0.0107 0.0191 0.0231
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0171 0.0208
Schistosoma mansoni chromatin regulatory protein sir2 0.0253 0.0517 0.0626
Brugia malayi ecdysteroid receptor 0.0031 0.0023 0.0028
Schistosoma mansoni leucine aminopeptidase 0.0022 0.0004 0.0004
Schistosoma mansoni peroxidasin 0.0275 0.0566 0.0687
Trichomonas vaginalis glycogen phosphorylase, putative 0.0114 0.0208 0.067
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.001 0.006
Onchocerca volvulus 0.0174 0.0342 0.0827
Echinococcus granulosus histone lysine methyltransferase setb 0.0098 0.0172 0.0172
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0112 0.0202 0.0649
Brugia malayi Cytochrome P450 family protein 0.0045 0.0053 0.0064
Schistosoma mansoni endothelin-converting enzyme-related 0.0024 0.0006 0.0008
Entamoeba histolytica calmodulin, putative 0.0182 0.0358 0.123
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Brugia malayi Proteasome subunit alpha type 7-1 0.0024 0.0007 0.0008
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1129 0.2464 0.2989
Trichomonas vaginalis calcineurin B subunit, putative 0.0182 0.0358 0.1166
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.01 0.0176 0.0515
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0049 0.0064 0.0186
Echinococcus multilocularis caspase 8 0.0071 0.0111 0.0111
Brugia malayi 20S proteasome alpha5 subunit 0.0024 0.0007 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1378 0.3021 1
Onchocerca volvulus Histone deacetylase 10 homolog 0.0077 0.0126 0.0304
Echinococcus granulosus cathepsin L 0.0327 0.0682 0.0682
Plasmodium vivax vivapain-2 0.1308 0.2865 1
Brugia malayi Cytochrome P450 family protein 0.0024 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0327 0.0682 0.0827
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0023 0.0028
Trichomonas vaginalis glutamate synthase, putative 0.01 0.0176 0.0564
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0094 0.0308
Onchocerca volvulus 0.0152 0.0291 0.0704
Loa Loa (eye worm) calpain D 0.0333 0.0695 0.0843
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0106 0.0129
Brugia malayi AMP-binding enzyme family protein 0.0025 0.001 0.0012
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0024 0.0007 0.0008
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0185 0.0365 0.0443
Echinococcus granulosus single minded 2 0.0038 0.0039 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Onchocerca volvulus 0.0037 0.0037 0.0089
Echinococcus multilocularis protein jagged 1 0.0025 0.0011 0.001
Brugia malayi Histone deacetylase family protein 0.0212 0.0426 0.0516
Mycobacterium ulcerans aldehyde dehydrogenase 0.0138 0.026 0.1545
Entamoeba histolytica cysteine proteinase, putative 0.0725 0.1567 0.5459
Trichomonas vaginalis conserved hypothetical protein 0.0333 0.0695 0.2285
Onchocerca volvulus 0.0057 0.0081 0.0195
Onchocerca volvulus 0.0031 0.0023 0.0055
Trichomonas vaginalis histone deacetylase, putative 0.0125 0.0233 0.075
Brugia malayi Cytochrome P450 family protein 0.0045 0.0053 0.0064
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0053 0.0064
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1561 0.3426 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.0169 0.0205
Trichomonas vaginalis set domain proteins, putative 0.0774 0.1677 0.5541
Echinococcus granulosus programmed cell death protein 0.0185 0.0366 0.0366
Giardia lamblia Proteasome subunit beta type 1 0.0078 0.0127 0.0401
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Trypanosoma brucei histone deacetylase 4 0.0212 0.0426 0.105
Trypanosoma cruzi histone deacetylase, putative 0.0212 0.0426 0.0516
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0053 0.0053
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0024 0.0007 0.0022
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.015 0.0503
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0024 0.0007 0.0006
Leishmania major hypothetical protein, conserved 0.01 0.0176 0.0439
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.01 0.0176 0.0214
Onchocerca volvulus 0.0182 0.0358 0.0866
Loa Loa (eye worm) hypothetical protein 0.0327 0.0682 0.0827
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0044
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0025 0.003
Giardia lamblia Cathepsin B precursor 0.1378 0.3021 1
Brugia malayi Animal haem peroxidase family protein 0.0275 0.0566 0.0687
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Brugia malayi Proteasome A-type and B-type family protein 0.0024 0.0007 0.0008
Echinococcus multilocularis glutamate synthase 0.01 0.0176 0.0176
Trypanosoma brucei metacaspase 0.0071 0.0111 0.0267
Giardia lamblia Transglutaminase/protease, putative 0.0297 0.0616 0.2021
Trypanosoma cruzi cysteine peptidase, putative 0.1418 0.3109 0.3771
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.1971
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0023 0.0028
Loa Loa (eye worm) hypothetical protein 0.0063 0.0094 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus multilocularis leucine aminopeptidase protein 0.0113 0.0205 0.0205
Trichomonas vaginalis calpain, putative 0.0333 0.0695 0.2285
Brugia malayi proteasome subunit beta type 2 0.005 0.0066 0.008
Plasmodium vivax histone deacetylase 1, putative 0.0125 0.0233 0.0812
Leishmania major proteasome alpha 1 subunit, putative 0.0024 0.0007 0.0016
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0078 0.0127 0.0444
Trypanosoma cruzi metacaspase, putative 0.0071 0.0111 0.0134
Echinococcus multilocularis 0.0024 0.0007 0.0007
Echinococcus multilocularis histone deacetylase 7 0.0212 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0048 0.0061 0.0073
Loa Loa (eye worm) glutathione reductase 0.1088 0.2375 0.288
Plasmodium falciparum cysteine proteinase falcipain 3 0.1308 0.2865 1
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0065 0.0099 0.0322
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0053 0.0053
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.0007 0.0009
Toxoplasma gondii aspartyl protease ASP3 0.0298 0.0616 0.1532
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.01 0.0176 0.0515
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0023 0.0028
Echinococcus granulosus protein jagged 2 0.0025 0.0011 0.001
Onchocerca volvulus 0.0054 0.0074 0.0179
Echinococcus granulosus Glycosyl transferase family 35 0.0114 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0045 0.0053 0.0065
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0253 0.0517 0.0516
Echinococcus multilocularis proteasome (prosome, macropain) 0.0164 0.0319 0.0319
Toxoplasma gondii histone deacetylase HDAC4 0.0077 0.0126 0.0312
Onchocerca volvulus 0.0152 0.0291 0.0704
Schistosoma mansoni glycogen phosphorylase 0.0049 0.0064 0.0077
Schistosoma mansoni caspase-3 (C14 family) 0.0215 0.0432 0.0524
Trypanosoma cruzi hypothetical protein, conserved 0.0267 0.0548 0.0665
Onchocerca volvulus Deterin homolog 0.0193 0.0384 0.0929
Plasmodium falciparum cysteine proteinase falcipain 1 0.0725 0.1567 0.5469
Brugia malayi A-kinase anchor protein 10, precursor 0.0045 0.0053 0.0065
Mycobacterium tuberculosis Probable oxidoreductase 0.0377 0.0793 0.2313
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.001 0.0013
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0024 0.0007 0.0016
Schistosoma mansoni glycogen phosphorylase 0.0114 0.0208 0.0253
Schistosoma mansoni calpain-7 (C02 family) 0.1132 0.2472 0.2998
Trypanosoma brucei Aph-1 protein, putative 0.0103 0.0183 0.0447
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0327 0.0682 0.0827
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0071 0.0111 0.0134
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1828 0.402 1
Leishmania major histone deacetylase, putative 0.0125 0.0233 0.0578
Echinococcus multilocularis proteasome subunit beta type 6 0.0024 0.0007 0.0006
Echinococcus multilocularis histone deacetylase 6 0.0212 0.0426 0.0426
Brugia malayi RNA binding protein 0.0068 0.0104 0.0127
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0024 0.0007 0.0022
Brugia malayi transcriptional regulator, Sir2 family protein 0.0065 0.0099 0.0119
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0142
Entamoeba histolytica cysteine proteinase, putative 0.1308 0.2865 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1721
Plasmodium falciparum cysteine repeat modular protein 1 0.0048 0.006 0.021
Onchocerca volvulus 0.0031 0.0023 0.0055
Loa Loa (eye worm) aspartyl protease 6 0.0054 0.0074 0.009
Trichomonas vaginalis hypothetical protein 0.0333 0.0695 0.2285
Brugia malayi notch-like transmembrane receptor 0.0025 0.0011 0.0013
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.01 0.0176 0.0515
Schistosoma mansoni chromatin regulatory protein sir2 0.0065 0.0099 0.0119
Brugia malayi Cathepsin L-like precursor 0.1308 0.2865 0.3475
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.01 0.0176 0.0564
Plasmodium vivax aspartyl protease, putative 0.0054 0.0074 0.0258
Schistosoma mansoni notch 0.0025 0.0011 0.0013
Onchocerca volvulus 0.0031 0.0023 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0053 0.0155
Onchocerca volvulus Cathepsin L homolog 0.1308 0.2865 0.6936
Trypanosoma cruzi cysteine proteinase, putative 0.0725 0.1567 0.19
Schistosoma mansoni centrin-related 0.0182 0.0358 0.0434
Mycobacterium ulcerans ferredoxin reductase 0.01 0.0176 0.1047
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.0007 0.0021
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.0007 0.0021
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0024 0.0007 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0377 0.0793 1
Entamoeba histolytica hypothetical protein 0.0045 0.0053 0.0164
Loa Loa (eye worm) hypothetical protein 0.0152 0.0291 0.0353
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.01 0.0176 0.0176
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0055 0.0161
Brugia malayi Papain family cysteine protease containing protein 0.0327 0.0682 0.0827
Brugia malayi Muscle positioning protein 4 0.0025 0.0011 0.0013
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.3188 0.7045 0.7045
Treponema pallidum oxidoreductase 0.01 0.0176 0.1815
Echinococcus multilocularis programmed cell death protein 0.0185 0.0366 0.0366
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0023 0.0056
Loa Loa (eye worm) hypothetical protein 0.0267 0.0548 0.0665
Brugia malayi Cathepsin L-like precursor 0.1308 0.2865 0.3475
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0023 0.0023
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Onchocerca volvulus 0.0025 0.0011 0.0025
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0053 0.0065
Schistosoma mansoni hypothetical protein 0.0182 0.0358 0.0434
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0078 0.0127 0.0423
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.0012
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.01 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0073 0.0117 0.0142
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0182 0.0358 0.0358
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Onchocerca volvulus 0.0025 0.001 0.0024
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0377 0.0793 0.4707
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.028 0.0576 0.0576
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0112 0.0202 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.6126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1378 0.3021 0.7513
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0039 0.0233
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.004 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0111 0.0346
Leishmania major cytochrome p450-like protein 0.0024 0.0007 0.0018
Plasmodium vivax plasmepsin IV, putative 0.0054 0.0074 0.0258
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0164 0.0319 0.1036
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0152 0.0291 0.0291
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1021 0.2225 0.2225
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0024 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0182 0.0358 0.0434
Trypanosoma cruzi cysteine peptidase, putative 0.0725 0.1567 0.19
Brugia malayi hypothetical protein 0.0152 0.0291 0.0353
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0377 0.0793 0.1971
Trichomonas vaginalis mercuric reductase, putative 0.0377 0.0793 0.2608
Leishmania major proteasome alpha 1 subunit, putative 0.0024 0.0007 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.0007 0.0021
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.0012
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Brugia malayi CXXC zinc finger family protein 0.0031 0.0023 0.0027
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0024 0.0007 0.0022
Schistosoma mansoni calpain C (C02 family) 0.1129 0.2464 0.2989
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Mycobacterium ulcerans hypothetical protein 0.01 0.0176 0.1047
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0778 0.1684 1
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0025 0.0011 0.0025
Plasmodium vivax SET domain protein, putative 0.0098 0.0172 0.0601
Giardia lamblia Cysteine protease 0.0327 0.0682 0.224
Trichomonas vaginalis calcium binding protein, putative 0.0185 0.0366 0.1194
Giardia lamblia Cathepsin B precursor 0.0327 0.0682 0.224
Loa Loa (eye worm) trypsin family protein 0.0152 0.0291 0.0353
Brugia malayi cathepsin F-like cysteine proteinase 0.0398 0.0839 0.1017
Brugia malayi cathepsin L precursor 0.0327 0.0682 0.0827
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0078 0.0127 0.0317
Leishmania major hypothetical protein, conserved 0.0333 0.0695 0.1729
Plasmodium falciparum plasmepsin X 0.0298 0.0616 0.2149
Leishmania major calmodulin, putative 0.0182 0.0358 0.089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0063 0.0094 0.0114
Trypanosoma cruzi kinesin, putative 0.0795 0.1723 0.209
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0327 0.0682 0.224
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0162 0.0314 0.1863
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0334 0.0696 0.1724
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0074 0.009
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0681 0.1468 0.178
Echinococcus granulosus Proteasome subunit alpha type 7 0.0024 0.0007 0.0006
Schistosoma mansoni histone deacetylase 4 5 0.0212 0.0426 0.0516
Mycobacterium ulcerans putative transglutaminase-like protein 0.0297 0.0616 0.3655
Toxoplasma gondii peptidase family M13 protein 0.0097 0.0169 0.0422
Echinococcus granulosus cathepsin l1 0.0911 0.198 0.198
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0053 0.0065
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0053 0.0065
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0182 0.0358 0.0434
Trypanosoma cruzi prolyl endopeptidase 0.1828 0.402 0.4877
Loa Loa (eye worm) PAS-3 protein 0.0024 0.0007 0.0008
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0333 0.0695 0.0843
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3188 0.7045 0.8546
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0024 0.0007 0.0008
Schistosoma mansoni histone deacetylase 1 2 3 0.0077 0.0126 0.0152
Trichomonas vaginalis centrin, putative 0.0182 0.0358 0.1166
Echinococcus multilocularis tumor protein p63 0.039 0.0821 0.0821
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0377 0.0793 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Giardia lamblia Cathepsin B precursor 0.0327 0.0682 0.224
Echinococcus granulosus caspase 0.0215 0.0432 0.0432
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.004 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1308 0.2865 0.9483
Loa Loa (eye worm) transcriptional regulator 0.0065 0.0099 0.0119
Brugia malayi MH2 domain containing protein 0.0133 0.0249 0.0302
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0023 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0725 0.1567 0.19
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Echinococcus multilocularis proteasome subunit alpha type 6 0.0024 0.0007 0.0006
Brugia malayi calcium-binding protein 0.0182 0.0358 0.0434
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0327 0.0682 0.2362
Trichomonas vaginalis calmodulin, putative 0.0182 0.0358 0.1166
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0023 0.0023
Brugia malayi programmed cell death protein 6 0.0182 0.0358 0.0434
Echinococcus granulosus leucyl aminopeptidase 0.0022 0.0004 0.0004
Leishmania major histone deacetylase, putative 0.0212 0.0426 0.1058
Loa Loa (eye worm) hypothetical protein 0.0327 0.0682 0.0827
Echinococcus granulosus RUN 0.0062 0.0091 0.0091
Echinococcus multilocularis calmodulin 0.0182 0.0358 0.0358
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.0682 0.224
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0022 0.0004 0.0004
Plasmodium vivax vivapain-1 0.0725 0.1567 0.5469
Echinococcus granulosus Transglutaminase 0.0297 0.0616 0.0615
Echinococcus multilocularis regulator of G protein signaling 0.0045 0.0053 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0172 0.0209
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0112 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0028
Brugia malayi Pre-SET motif family protein 0.0681 0.1468 0.178
Brugia malayi cytochrome P450 0.0024 0.0007 0.0009
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0185 0.0365 0.0443
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0778 0.1684 0.4183
Schistosoma mansoni histone deacetylase hda2 0.0225 0.0455 0.0552
Schistosoma mansoni glutamate synthase 0.01 0.0176 0.0214
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0327 0.0682 0.0827
Echinococcus multilocularis microtubule associated protein 2 0.1593 0.3498 0.3498
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0023 0.0023
Schistosoma mansoni cpg binding protein 0.0031 0.0023 0.0027
Toxoplasma gondii centrin, putative 0.0182 0.0358 0.089
Echinococcus granulosus cathepsin l1 0.1308 0.2865 0.2865
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0024 0.0007 0.0016
Loa Loa (eye worm) calpain 5 0.0795 0.1723 0.209
Entamoeba histolytica cysteine protease, putative 0.0327 0.0682 0.2362
Loa Loa (eye worm) hypothetical protein 0.0135 0.0254 0.0308
Schistosoma mansoni chromatin regulatory protein sir2 0.028 0.0576 0.0699
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0649 0.1399 0.3472
Loa Loa (eye worm) calpain family protein 1 0.3006 0.6641 0.8056
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0053 0.0065
Onchocerca volvulus Cathepsin L homolog 0.1308 0.2865 0.6936
Brugia malayi prolyl oligopeptidase family protein 0.0649 0.1399 0.1696
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.01 0.0176 0.2162
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0022 0.0004 0.0004
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0078 0.0127 0.0154
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0193 0.0384 0.0384
Trichomonas vaginalis calmodulin, putative 0.0182 0.0358 0.1166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0911 0.198 0.6547
Schistosoma mansoni notch 0.0025 0.0011 0.0013
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1378 0.3021 0.3664
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.0843
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.01 0.0176 0.1047
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0097 0.0169 0.0205
Schistosoma mansoni inhibitor of apoptosis protein 0.0193 0.0384 0.0466
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.004 0.004
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0193 0.0384 0.0466
Loa Loa (eye worm) hypothetical protein 0.0054 0.0074 0.009
Onchocerca volvulus 0.0031 0.0023 0.0055
Brugia malayi EGF-like domain containing protein 0.0025 0.0011 0.0013
Brugia malayi Animal haem peroxidase family protein 0.0275 0.0566 0.0687
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0023 0.0028
Toxoplasma gondii hypothetical protein 0.0333 0.0695 0.1729
Echinococcus multilocularis caspase 3 0.0144 0.0275 0.0275
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0024 0.0007 0.0008
Brugia malayi calpain 5 0.0795 0.1723 0.209
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0023 0.0056
Entamoeba histolytica cysteine protease, putative 0.0327 0.0682 0.2362
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Echinococcus multilocularis neurocalcin 0.0182 0.0358 0.0358
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.0961
Trypanosoma cruzi histone deacetylase, putative 0.0077 0.0126 0.0152
Brugia malayi PXA domain containing protein 0.0045 0.0053 0.0065
Trypanosoma brucei C-8 sterol isomerase, putative 0.0371 0.0778 0.1928
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0182 0.0358 0.0434
Giardia lamblia Sirtuin type 2 0.0065 0.0099 0.0305
Trypanosoma cruzi centrin, putative 0.0185 0.0366 0.0444
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0066 0.008
Trypanosoma cruzi cysteine peptidase, putative 0.1308 0.2865 0.3475
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Mycobacterium tuberculosis Hypothetical protein 0.0297 0.0616 0.1796
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.004 0.0116
Brugia malayi AMP-binding enzyme family protein 0.0025 0.001 0.0012
Plasmodium falciparum calpain 0.0333 0.0695 0.2426
Onchocerca volvulus 0.0062 0.0091 0.022
Toxoplasma gondii microneme protein MIC17C 0.0031 0.0023 0.0056
Brugia malayi Cytochrome P450 family protein 0.0069 0.0106 0.0129
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.01 0.0176 0.0176
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1378 0.3021 0.3664
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0011 0.001
Trichomonas vaginalis calpain, putative 0.0333 0.0695 0.2285
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.0007 0.0021
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0063 0.0094 0.0094
Loa Loa (eye worm) histone deacetylase 3 0.0125 0.0233 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0333 0.0695 0.2285
Loa Loa (eye worm) fibroinase 0.1308 0.2865 0.3475
Trypanosoma brucei trypanothione reductase 0.1088 0.2375 0.5902
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0053 0.0053
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0024 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0077 0.0126 0.0152
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0024 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0094 0.0114
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.028 0.0576 0.1891
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.0012
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0024 0.0007 0.0008
Brugia malayi Calmodulin-like protein 0.0182 0.0358 0.0434
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.0007 0.0021
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0094 0.0162 0.0162
Toxoplasma gondii ABC1 family protein 0.0037 0.0037 0.0091
Trichomonas vaginalis calmodulin, putative 0.0185 0.0365 0.119
Plasmodium vivax unspecified product 0.0327 0.0682 0.2379
Brugia malayi Trypsin family protein 0.0152 0.0291 0.0353
Entamoeba histolytica cysteine proteinase, putative 0.1308 0.2865 1
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0024 0.0007 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0398 0.0839 0.1017
Echinococcus granulosus Polycystic kidney disease protein 0.0062 0.0091 0.0091
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.01 0.0176 0.0439
Echinococcus granulosus thioredoxin glutathione reductase 0.1088 0.2375 0.2374
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0377 0.0793 0.1971
Trypanosoma brucei Metacaspase-4 0.0071 0.0111 0.0267
Trypanosoma cruzi cysteine peptidase, putative 0.1418 0.3109 0.3771
Brugia malayi Serine carboxypeptidase S28 family protein 0.0063 0.0094 0.0114
Echinococcus multilocularis programmed cell death protein 0.0185 0.0366 0.0366
Toxoplasma gondii centrin 0.0182 0.0358 0.089
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0065 0.0099 0.0343
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1088 0.2375 0.6931
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0024 0.0007 0.0016
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.004 0.0111
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.001 0.0025
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0024 0.0006 0.0008
Plasmodium falciparum plasmepsin V 0.0054 0.0074 0.0258
Leishmania major calpain family cysteine protease-like protein 0.0333 0.0695 0.1729
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0377 0.0793 0.1964
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0138 0.026 0.026
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0398 0.0839 0.1017
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0377 0.0793 0.4707
Brugia malayi NAD-dependent deacetylase SIRT1 0.028 0.0576 0.0699
Echinococcus multilocularis expressed protein 0.0871 0.1892 0.1892
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0353
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0162 0.0314 0.1863
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0065 0.0099 0.0287
Echinococcus granulosus histone deacetylase 0.0212 0.0426 0.0426
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0023 0.0028
Onchocerca volvulus 0.0031 0.0023 0.0055
Echinococcus granulosus caspase 8 0.0071 0.0111 0.0111
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0053 0.0064
Plasmodium vivax proteasome subunit beta type-5, putative 0.0164 0.0319 0.1112
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0022 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.1308 0.2865 0.7126
Loa Loa (eye worm) hypothetical protein 0.0214 0.0431 0.0523
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1129 0.2464 0.6126
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.0063 0.0076
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0327 0.0682 0.0827
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1308 0.2865 0.3475
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.01 0.0176 0.1047
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0053 0.0065
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.01 0.0176 0.0439
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Schistosoma mansoni hypothetical protein 0.0094 0.0162 0.0196
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1 0.0142 0.027 0.0787
Brugia malayi hypothetical protein 0.0062 0.0091 0.011
Trypanosoma cruzi calmodulin, putative 0.0182 0.0358 0.0434
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0027
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.001 0.006
Trypanosoma cruzi calmodulin, putative 0.0182 0.0358 0.0434
Loa Loa (eye worm) hypothetical protein 0.0032 0.0025 0.003
Schistosoma mansoni cathepsin D (A01 family) 0.0338 0.0706 0.0857
Leishmania major calmodulin-like protein 0.0182 0.0358 0.089
Trichomonas vaginalis disulfide oxidoreductase, putative 0.01 0.0176 0.0564
Toxoplasma gondii proteasome subunit alpha type, putative 0.0024 0.0007 0.0016
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0012 0.004
Brugia malayi Doublecortin family protein 0.0062 0.0091 0.011
Plasmodium falciparum ferrodoxin reductase-like protein 0.01 0.0176 0.0616
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0024 0.0007 0.0022
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0164 0.0319 0.1092
Leishmania major hypothetical protein, conserved 0.01 0.0176 0.0439
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0164 0.0319 0.1036
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.004 0.0111
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0024 0.0007 0.0008
Toxoplasma gondii hypothetical protein 0.0267 0.0548 0.1363
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Onchocerca volvulus Cell death protein 3 homolog 0.0214 0.0431 0.1043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0333 0.0695 0.0843
Leishmania major cytochrome p450-like protein 0.0024 0.0007 0.0018
Toxoplasma gondii heat shock protein hslv, putative 0.0024 0.0007 0.0016
Echinococcus multilocularis cathepsin b 0.3726 0.8244 0.8244
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0101 0.025
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0023 0.0028
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0037 0.01
Entamoeba histolytica prolyl oligopeptidase family protein 0.0267 0.0548 0.1895
Schistosoma mansoni chromatin regulatory protein sir2 0.0253 0.0517 0.0626
Brugia malayi Trypsin family protein 0.0152 0.0291 0.0353
Brugia malayi histone deacetylase 11 0.0077 0.0126 0.0152
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1129 0.2464 0.2989
Plasmodium falciparum plasmepsin IX 0.0298 0.0616 0.2149
Onchocerca volvulus 0.1308 0.2865 0.6936
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0054 0.0074 0.009
Loa Loa (eye worm) transcriptional regulator 0.0253 0.0517 0.0626
Trypanosoma brucei proteasome subunit beta type-2, putative 0.005 0.0066 0.0154
Plasmodium vivax histone deacetylase 2, putative 0.0212 0.0426 0.1485
Brugia malayi Eukaryotic aspartyl protease family protein 0.0054 0.0074 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0053 0.0065
Echinococcus granulosus proteasome subunit beta t family 0.0024 0.0007 0.0006
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0024 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0044
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0333 0.0695 0.0843
Schistosoma mansoni ef hand domain family member A2 0.0182 0.0358 0.0434
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1308 0.2865 0.9483
Trypanosoma brucei calpain-like protein, putative 0.1129 0.2464 0.6126
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1021 0.2225 0.2225
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.01 0.0176 0.0564
Loa Loa (eye worm) hypothetical protein 0.3726 0.8244 1
Brugia malayi hypothetical protein 0.0054 0.0074 0.009
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1828 0.402 0.4877
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0112 0.0202 0.0245
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0358 0.0434
Brugia malayi Cathepsin L-like precursor 0.1308 0.2865 0.3475
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.01 0.0176 0.0616
Echinococcus multilocularis fibropellin Ia 0.0025 0.0011 0.001
Toxoplasma gondii EFHC1, putative 0.0182 0.0358 0.089
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0327 0.0682 0.0827
Entamoeba histolytica glycogen phosphorylase, putative 0.0114 0.0208 0.0706
Mycobacterium tuberculosis Conserved protein 0.0037 0.0037 0.0107
Plasmodium falciparum metacaspase-like protein 0.0071 0.0111 0.0387
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0327 0.0682 0.2379
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.001 0.0029
Trypanosoma cruzi major cysteine proteinase, putative 0.0437 0.0926 0.1123
Brugia malayi Blistered cuticle protein 3 0.0275 0.0566 0.0687
Trypanosoma brucei histone deacetylase 3 0.0212 0.0426 0.105
Toxoplasma gondii cathepsin CPC1 0.0327 0.0682 0.1696
Toxoplasma gondii cathepsin CPL 0.1308 0.2865 0.7126
Onchocerca volvulus Putative cubilin 0.0025 0.0011 0.0025
Giardia lamblia Glutamate synthase 0.01 0.0176 0.0564
Plasmodium vivax aspartyl proteinase, putative 0.0054 0.0074 0.0258
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0063 0.0094 0.0114
Toxoplasma gondii kringle domain-containing protein 0.0048 0.006 0.015
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0037 0.0037
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0037 0.0107
Schistosoma mansoni gamma-secretase subunit aph-1 0.0265 0.0543 0.0658
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0152 0.0291 0.0353
Toxoplasma gondii proteasome subunit beta type, putative 0.0164 0.0319 0.0793
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0013
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0063 0.0094 0.0308
Plasmodium vivax aspartyl protease, putative 0.0298 0.0616 0.2149
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0023 0.0028
Echinococcus multilocularis thioredoxin glutathione reductase 0.1088 0.2375 0.2374
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0778 0.1684 0.2042
Toxoplasma gondii histone deacetylase HDAC1 0.0212 0.0426 0.1059
Entamoeba histolytica cysteine protease, putative 0.0725 0.1567 0.5459
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0024 0.0007 0.0008
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0725 0.1567 0.19
Echinococcus multilocularis calpain 5 0.1129 0.2464 0.2464
Echinococcus granulosus transmembrane protease serine 3 0.0152 0.0291 0.0291
Plasmodium falciparum glutathione reductase 0.1088 0.2375 0.8288
Giardia lamblia Thioredoxin reductase 0.01 0.0176 0.0564
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0152 0.0291 0.0291
Giardia lamblia Cathepsin B precursor 0.0327 0.0682 0.224
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0171 0.0171
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0267 0.0548 0.1797
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.01 0.0176 0.0176
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0012 0.0017
Trichomonas vaginalis calcium binding protein, putative 0.0182 0.0358 0.1166
Plasmodium falciparum proteasome subunit beta type-2, putative 0.005 0.0066 0.0229
Onchocerca volvulus 0.01 0.0176 0.0427
Onchocerca volvulus Putative alcohol dehydrogenase 0.0162 0.0314 0.0759
Loa Loa (eye worm) peptidase family M13 containing protein 0.0072 0.0113 0.0137
Onchocerca volvulus 0.0031 0.0023 0.0055
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.01 0.0176 0.0595
Loa Loa (eye worm) cysteine protease 0.1308 0.2865 0.3475
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0024 0.0007 0.0016
Entamoeba histolytica prolyl oligopeptidase family protein 0.0267 0.0548 0.1895
Brugia malayi calpain 7 0.1129 0.2464 0.2989
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0162 0.0314 0.1863
Brugia malayi beta-lactamase 0.0037 0.0037 0.0044
Brugia malayi Proteasome A-type and B-type family protein 0.0024 0.0007 0.0008
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0011 0.0013
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0066 0.0197
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0053 0.0122
Brugia malayi glutathione reductase 0.1088 0.2375 0.288
Schistosoma mansoni histone deacetylase 0.0125 0.0233 0.0282
Echinococcus granulosus cathepsin b 0.3726 0.8244 0.8244
Trypanosoma brucei prolyl endopeptidase 0.1828 0.402 1
Brugia malayi PXA domain containing protein 0.0045 0.0053 0.0065
Brugia malayi proteasome subunit beta type 1 0.0078 0.0127 0.0154
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0098 0.0172 0.0172
Giardia lamblia Hypothetical protein 0.0253 0.0517 0.1692
Schistosoma mansoni glutamate synthase 0.01 0.0176 0.0214
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0172 0.0209
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0049 0.0063 0.0076
Schistosoma mansoni cathepsin B (C01 family) 0.0327 0.0682 0.0827
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0063 0.0094 0.0292
Onchocerca volvulus 0.0182 0.0358 0.0866
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.0007 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0023 0.0056
Echinococcus granulosus protein jagged 1 0.0025 0.0011 0.001
Plasmodium vivax aspartyl proteinase, putative 0.0054 0.0074 0.0258
Mycobacterium ulcerans transglutaminase family protein 0.0297 0.0616 0.3655
Onchocerca volvulus 0.0152 0.0291 0.0704
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0024 0.0007 0.0008
Leishmania major C-8 sterol isomerase-like protein 0.0371 0.0778 0.1935
Entamoeba histolytica hypothetical protein, conserved 0.0185 0.0365 0.1255
Trichomonas vaginalis apoptosis inducing factor, putative 0.01 0.0176 0.0564
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0047 0.0141
Trypanosoma cruzi centrin-3 0.0185 0.0366 0.0444
Loa Loa (eye worm) hypothetical protein 0.0174 0.0342 0.0414
Echinococcus granulosus calbindin 32 0.0185 0.0365 0.0365
Trypanosoma cruzi kinesin, putative 0.0795 0.1723 0.209
Trypanosoma brucei calpain-like protein, putative 0.1129 0.2464 0.6126
Loa Loa (eye worm) doublecortin family protein 0.0062 0.0091 0.011
Schistosoma mansoni neprilysin 0.0025 0.001 0.0012
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0023 0.0028
Onchocerca volvulus 0.0275 0.0566 0.137
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0023 0.0023
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0007 0.0043
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.0007 0.0043
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0023 0.0056
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0037 0.0217
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.004 0.0048
Toxoplasma gondii microneme protein MIC17A 0.0031 0.0023 0.0056
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.004 0.0236
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0023 0.0028
Plasmodium vivax proteasome subunit beta type-7, putative 0.0024 0.0007 0.0022
Onchocerca volvulus 0.0775 0.1677 0.4061
Trichomonas vaginalis disulfide oxidoreductase, putative 0.01 0.0176 0.0564
Giardia lamblia Proteasome subunit beta type 2 0.005 0.0066 0.0197
Leishmania major centrin, putative,caltractin, putative 0.0182 0.0358 0.089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0333 0.0695 0.0843
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0152 0.0291 0.0353
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Schistosoma mansoni hypothetical protein 0.0094 0.0162 0.0196
Schistosoma mansoni hypothetical protein 0.0025 0.0011 0.0013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0023 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0023 0.0028
Loa Loa (eye worm) RGS-3 protein 0.0045 0.0053 0.0065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1129 0.2464 0.2989
Trypanosoma brucei NADH dehydrogenase 0.01 0.0176 0.043
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0104 0.0127
Brugia malayi Proteasome A-type and B-type family protein 0.0164 0.0319 0.0386
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0182 0.0358 0.0434
Plasmodium falciparum serine repeat antigen 8 0.0327 0.0682 0.2379
Loa Loa (eye worm) hypothetical protein 0.0182 0.0358 0.0434
Giardia lamblia NADH oxidase lateral transfer candidate 0.0377 0.0793 0.2608
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1308 0.2865 0.9483
Echinococcus multilocularis histone deacetylase 6 0.0212 0.0426 0.0426
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.01 0.0176 0.0616
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0162 0.0314 0.1863
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.005 0.0066 0.0066
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.01 0.0176 0.0176
Echinococcus granulosus peroxidasin 0.0275 0.0566 0.0566
Trypanosoma cruzi cysteine peptidase, putative 0.1418 0.3109 0.3771
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0253 0.0517 0.1784
Schistosoma mansoni hypothetical protein 0.0024 0.0007 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.0007 0.0021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0327 0.0682 0.0827
Trichomonas vaginalis calmodulin, putative 0.0185 0.0366 0.1194
Loa Loa (eye worm) hypothetical protein 0.0152 0.0291 0.0353
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0275 0.0565 0.165
Schistosoma mansoni apoptosis regulator bax 0.0094 0.0162 0.0196
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0023 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0111 0.0387
Trichomonas vaginalis glutathione reductase, putative 0.0377 0.0793 0.2608
Onchocerca volvulus 0.0297 0.0616 0.149
Echinococcus granulosus fibropellin Ia 0.0025 0.0011 0.001
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0023 0.0056
Loa Loa (eye worm) MH2 domain-containing protein 0.0133 0.0249 0.0302
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.0007 0.0043
Loa Loa (eye worm) hypothetical protein 0.0398 0.0839 0.1017
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0215 0.0432 0.0432
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0045 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0682 0.224
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1129 0.2464 0.2989
Mycobacterium tuberculosis Conserved hypothetical protein 0.0297 0.0616 0.1796
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0113 0.0205 0.0714
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Leishmania major sir2-family protein-like protein 0.0065 0.0099 0.0245
Echinococcus multilocularis cysteine protease 0.1308 0.2865 0.2865
Brugia malayi Cathepsin L-like precursor 0.1308 0.2865 0.3475
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0094 0.0292
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0024 0.0007 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.0007 0.0021
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.004 0.0139
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0113 0.0205 0.05
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.0007 0.0021
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.01 0.0176 0.0564
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0044
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.01 0.0176 0.043
Entamoeba histolytica hypothetical protein, conserved 0.0065 0.0099 0.0322
Onchocerca volvulus 0.0048 0.006 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0023 0.0028
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0024 0.0007 0.0008
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0023 0.0023
Echinococcus granulosus calcium uptake protein 1 0.0185 0.0365 0.0365
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0333 0.0695 0.1729
Plasmodium falciparum histone deacetylase 2 0.0212 0.0426 0.1485
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.01 0.0176 0.0439
Loa Loa (eye worm) hypothetical protein 0.0275 0.0566 0.0687
Brugia malayi Cathepsin L-like precursor 0.1308 0.2865 0.3475
Entamoeba histolytica glycogen phosphorylase, putative 0.0114 0.0208 0.0706
Plasmodium vivax serine-repeat antigen (SERA) 0.0327 0.0682 0.2379
Echinococcus granulosus glycogen phosphorylase 0.0114 0.0208 0.0208
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0162 0.0314 0.1863
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.01 0.0176 0.0176
Schistosoma mansoni aldehyde dehydrogenase 0.0138 0.026 0.0316
Schistosoma mansoni cercarial elastase (S01 family) 0.0152 0.0291 0.0353
Echinococcus multilocularis Mastin 0.0152 0.0291 0.0291
Leishmania major hypothetical protein, conserved 0.0185 0.0365 0.0908
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0053 0.0065
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.0484 0.1411
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.0012
Giardia lamblia Cathepsin L precursor 0.0327 0.0682 0.224
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0011 0.001
Brugia malayi Trypsin family protein 0.0152 0.0291 0.0353
Leishmania major calcineurin B subunit, putative 0.0182 0.0358 0.089
Loa Loa (eye worm) hypothetical protein 0.0097 0.0169 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0111 0.0346
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1418 0.3109 0.7731
Brugia malayi PAN domain containing protein 0.0031 0.0023 0.0027
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0063 0.0094 0.0292
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.01 0.0176 0.0515
Schistosoma mansoni single-minded 0.0052 0.007 0.0084
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0327 0.0682 0.224
Entamoeba histolytica cysteine proteinase, putative 0.0725 0.1567 0.5459
Trichomonas vaginalis disulfide oxidoreductase, putative 0.01 0.0176 0.0564
Trypanosoma brucei hypothetical protein, conserved 0.01 0.0176 0.043
Echinococcus multilocularis transmembrane protease serine 3 0.0152 0.0291 0.0291
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0004 0.0004
Echinococcus multilocularis calpain 0.1129 0.2464 0.2464
Brugia malayi EGF-like domain containing protein 0.0025 0.0011 0.0013
Mycobacterium ulcerans hypothetical protein 0.0297 0.0616 0.3655
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0053 0.0053
Mycobacterium tuberculosis Putative ferredoxin reductase 0.01 0.0176 0.0515
Brugia malayi Protein kinase domain containing protein 0.0048 0.006 0.0073
Brugia malayi cathepsin Z-like cysteine proteinase 0.0327 0.0682 0.0827
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0054 0.0074 0.0224
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0024 0.0007 0.0006
Echinococcus multilocularis tissue type plasminogen activator 0.0048 0.006 0.006
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0007 0.0009
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0006 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.001 0.0025
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0267 0.0548 0.1797
Leishmania major trypanothione reductase 0.1088 0.2375 0.5906
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0071 0.0111 0.0346
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.3188 0.7045 0.7045
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 137 nM Inhibition of human recombinant phosphodiesterase 4A ChEMBL. 12031318
IC50 (binding) = 137 nM Inhibition of human recombinant phosphodiesterase 4A ChEMBL. 12031318
IC50 (functional) = 4.3 uM Inhibition of LPS-stimulated TNF-alpha production in human whole blood ChEMBL. 12031318
IC50 (functional) = 4.3 uM Inhibition of LPS-stimulated TNF-alpha production in human whole blood ChEMBL. 12031318

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 12031318

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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