Detailed information for compound 50925

Basic information

Technical information
  • TDR Targets ID: 50925
  • Name: 5-(1-azabicyclo[2.2.2]octan-8-yl)-3-(1-methyl indol-3-yl)-1,2,4-oxadiazole
  • MW: 308.378 | Formula: C18H20N4O
  • H donors: 0 H acceptors: 2 LogP: 2.53 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cn1cc(c2c1cccc2)c1noc(n1)C1CN2CCC1CC2
  • InChi: 1S/C18H20N4O/c1-21-10-15(13-4-2-3-5-16(13)21)17-19-18(23-20-17)14-11-22-8-6-12(14)7-9-22/h2-5,10,12,14H,6-9,11H2,1H3
  • InChiKey: LBRWDGATMOZICE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-(1-methylindol-3-yl)-5-quinuclidin-3-yl-1,2,4-oxadiazole
  • 3-(1-methyl-3-indolyl)-5-(3-quinuclidinyl)-1,2,4-oxadiazole
  • 3-[5-(1-azabicyclo[2.2.2]octan-8-yl)-1,2,4-oxadiazol-3-yl]-1-methylindole
  • 1-methyl-3-(5-quinuclidin-3-yl-1,2,4-oxadiazol-3-yl)indole
  • 1-methyl-3-[5-(3-quinuclidinyl)-1,2,4-oxadiazol-3-yl]indole
  • 3-[5-(1-azabicyclo[2.2.2]octan-8-yl)-1,2,4-oxadiazol-3-yl]-1-methyl-indole

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Serotonin 3 (5-HT3) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 461 aa 24.3 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 452 aa 29.2 %
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) Serotonin 3 (5-HT3) receptor   483 aa 503 aa 22.3 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein Serotonin 3 (5-HT3) receptor   483 aa 388 aa 21.9 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog Serotonin 3 (5-HT3) receptor   483 aa 465 aa 27.3 %
Schistosoma japonicum Neuronal acetylcholine receptor subunit alpha-3 precursor, putative Serotonin 3 (5-HT3) receptor   483 aa 505 aa 21.2 %
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit Serotonin 3 (5-HT3) receptor   483 aa 445 aa 25.6 %
Onchocerca volvulus Putative zinc finger protein Serotonin 3 (5-HT3) receptor   483 aa 489 aa 25.8 %
Onchocerca volvulus 39S ribosomal protein L13, mitochondrial homolog Serotonin 3 (5-HT3) receptor   483 aa 490 aa 31.0 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 473 aa 27.5 %
Loa Loa (eye worm) acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 484 aa 26.0 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type des-2 homolog Serotonin 3 (5-HT3) receptor   483 aa 464 aa 24.8 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog Serotonin 3 (5-HT3) receptor   483 aa 482 aa 25.1 %
Brugia malayi Cation transporter family protein Serotonin 3 (5-HT3) receptor   483 aa 507 aa 28.2 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 489 aa 31.3 %
Schistosoma japonicum Neuronal acetylcholine receptor subunit alpha-9-II precursor, putative Serotonin 3 (5-HT3) receptor   483 aa 457 aa 24.7 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 477 aa 26.6 %
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative Serotonin 3 (5-HT3) receptor   483 aa 514 aa 23.2 %
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 Serotonin 3 (5-HT3) receptor   483 aa 387 aa 25.6 %
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 470 aa 27.7 %
Echinococcus multilocularis nAChR subunit Serotonin 3 (5-HT3) receptor   483 aa 495 aa 24.2 %
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 457 aa 26.7 %
Drosophila melanogaster nicotinic Acetylcholine Receptor alpha2 Serotonin 3 (5-HT3) receptor   483 aa 541 aa 25.5 %
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor Serotonin 3 (5-HT3) receptor   483 aa 457 aa 26.9 %
Onchocerca volvulus Large subunit GTPase 1 homolog Serotonin 3 (5-HT3) receptor   483 aa 394 aa 19.3 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 482 aa 23.9 %
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit Serotonin 3 (5-HT3) receptor   483 aa 445 aa 25.4 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative Serotonin 3 (5-HT3) receptor   483 aa 478 aa 25.1 %
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 470 aa 26.8 %
Brugia malayi acetylcholine receptor alpha subunit precursor, putative Serotonin 3 (5-HT3) receptor   483 aa 463 aa 26.8 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog Serotonin 3 (5-HT3) receptor   483 aa 465 aa 27.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi histone deacetylase 1 (HD1) 0.0087 0.0167 0.0166
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0319 0.1167
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0049 0.0049
Echinococcus granulosus histone deacetylase 6 0.0104 0.0213 0.0212
Echinococcus multilocularis histone deacetylase 0.0098 0.0196 0.0195
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0302 0.0754 0.2195
Leishmania major protein kinase, putative 0.0182 0.0428 0.0684
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0196 0.0189
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.004 0.004 0.0053
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.032 0.0804 0.2341
Brugia malayi CXXC zinc finger family protein 0.0034 0.0022 0.0021
Echinococcus granulosus programmed cell death protein 0.0186 0.0438 0.0437
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0182 0.0428 0.042
Brugia malayi proteasome subunit alpha type 4 0.004 0.004 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.0804 0.2187
Echinococcus multilocularis dnaJ subfamily B 0.0483 0.1248 0.1247
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0196 0.0195
Echinococcus multilocularis proteasome subunit beta type 7 0.004 0.004 0.0039
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0182 0.0428 0.0427
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0103 0.0212 0.0212
Echinococcus granulosus peroxidasin 0.0325 0.0818 0.0817
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0048
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.004 0.004 0.0033
Echinococcus granulosus proteasome subunit beta type 7 0.004 0.004 0.0039
Giardia lamblia Proteasome subunit beta type 4 precursor 0.004 0.004 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.032 0.0804 0.0803
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0818 0.0817
Trypanosoma cruzi I/6 autoantigen, putative 0.0182 0.0428 0.042
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0052 0.0071 0.0059
Trypanosoma brucei proteasome beta-1 subunit, putative 0.004 0.004 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0134 0.0348
Schistosoma mansoni calpain C (C02 family) 0.1164 0.3108 0.3108
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0076 0.0138 0.0137
Trypanosoma cruzi metacaspase, putative 0.0062 0.0099 0.0092
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0344 0.0869 0.2366
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0103 0.0212 0.0211
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0029 0.0028
Mycobacterium ulcerans hypothetical protein 0.0075 0.0134 0.0424
Onchocerca volvulus 0.1935 0.5216 0.8481
Toxoplasma gondii calmodulin CAM1 0.0185 0.0436 0.0704
Brugia malayi Peroxidasin 0.0325 0.0818 0.0817
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0015 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Brugia malayi Calmodulin-like protein 0.0182 0.0428 0.0427
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1164 0.3108 0.3103
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0095 0.0143
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0134 0.0133
Brugia malayi Cathepsin L-like precursor 0.1274 0.3409 0.3408
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0029 0.0034
Trypanosoma brucei metacaspase 0.0062 0.0099 0.0149
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0319 0.1167
Brugia malayi Trypsin family protein 0.0192 0.0455 0.0454
Toxoplasma gondii microneme protein MIC17B 0.0031 0.0015 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0134 0.0127
Giardia lamblia Cysteine protease 0.032 0.0804 0.2198
Giardia lamblia Proteasome subunit beta type 9 precursor 0.004 0.004 0.0103
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.0804 0.0804
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0344 0.0869 0.0862
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.004 0.0039
Trypanosoma brucei metacaspase MCA2 0.0062 0.0099 0.0149
Mycobacterium tuberculosis Probable peptidase 0.0948 0.2519 0.469
Leishmania major cathepsin L-like protease 0.1381 0.3702 0.6015
Schistosoma mansoni Mername-AA248 (C02 family) 0.1164 0.3108 0.3108
Echinococcus granulosus transmembrane protease serine 3 0.0192 0.0455 0.0454
Schistosoma mansoni cpg binding protein 0.0036 0.0028 0.0028
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0095 0.0257
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0041 0.0043 0.0042
Giardia lamblia Cathepsin L precursor 0.032 0.0804 0.2198
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0095 0.0088
Loa Loa (eye worm) hypothetical protein 0.0192 0.0455 0.0454
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Echinococcus multilocularis glycogen phosphorylase 0.012 0.0257 0.0256
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0043 0.0049 0.0048
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Echinococcus multilocularis programmed cell death protein 0.0186 0.0438 0.0437
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0167 0.0438
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Plasmodium vivax vivapain-2 0.1274 0.3409 1
Trypanosoma cruzi oligopeptidase b 0.0948 0.2519 0.2513
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0186 0.0438 0.0437
Loa Loa (eye worm) hypothetical protein 0.0048 0.0062 0.0061
Echinococcus multilocularis regulator of G protein signaling 0.0044 0.0049 0.0048
Brugia malayi calpain family protein 1 0.3099 0.8394 0.8394
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1274 0.3409 0.3408
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0049 0.0115
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.004 0.0053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Brugia malayi proteasome subunit alpha type 2 0.004 0.004 0.0039
Echinococcus multilocularis caspase 0.0134 0.0297 0.0296
Loa Loa (eye worm) papain family cysteine protease containing protein 0.032 0.0804 0.0803
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.004 0.004 0.0061
Leishmania major hypothetical protein, conserved 0.0048 0.0062 0.0088
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0637 0.1669 0.1663
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0003
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Plasmodium falciparum metacaspase-like protein 0.0062 0.0099 0.0269
Leishmania major cathepsin L-like protease 0.1381 0.3702 0.6015
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0948 0.2519 0.4089
Brugia malayi Delta serrate ligand family protein 0.0027 0.0003 0.0002
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0196 0.0195
Trypanosoma cruzi metacaspase 5, putative 0.0062 0.0099 0.0092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Toxoplasma gondii aspartyl protease 0.0043 0.0049 0.0075
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.0683 0.0682
Brugia malayi Flap endonuclease-1 0.0028 0.0007 0.0006
Onchocerca volvulus 0.0031 0.0015 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0134 0.0134
Echinococcus granulosus neuronal calcium sensor 0.0182 0.0428 0.0427
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.004 0.0039
Plasmodium vivax unspecified product 0.0707 0.186 0.5446
Entamoeba histolytica glycogenphosphorylase, putative 0.0052 0.0071 0.0188
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0049 0.0048
Loa Loa (eye worm) fli-1 protein 0.0221 0.0533 0.0532
Onchocerca volvulus Peroxidase homolog 0.0325 0.0818 0.1328
Brugia malayi Histone deacetylase family protein 0.0098 0.0196 0.0195
Giardia lamblia Cathepsin B precursor 0.032 0.0804 0.2198
Loa Loa (eye worm) hypothetical protein 0.0057 0.0086 0.0085
Schistosoma mansoni calpain (C02 family) 0.1164 0.3108 0.3108
Giardia lamblia Thymus-specific serine protease precursor 0.0041 0.0043 0.0111
Trypanosoma cruzi metacaspase 5, putative 0.0062 0.0099 0.0092
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.032 0.0804 0.2341
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3687 1 1
Onchocerca volvulus 0.0031 0.0015 0.0023
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Onchocerca volvulus 0.0041 0.0043 0.0068
Echinococcus granulosus Glycosyl transferase family 35 0.012 0.0257 0.0256
Loa Loa (eye worm) ctsf protein 0.1274 0.3409 0.3408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0143 0.0322 0.0321
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0344 0.0869 0.0862
Echinococcus multilocularis cathepsin L 0.032 0.0804 0.0803
Onchocerca volvulus 0.0182 0.0428 0.0694
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0062 0.0099 0.0157
Brugia malayi hypothetical protein 0.0192 0.0455 0.0454
Echinococcus granulosus EF HAND 1 calcium binding site 0.0182 0.0428 0.0427
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.004 0.004
Trypanosoma brucei histone deacetylase 2 0.0042 0.0044 0.006
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0771 0.2037 0.2037
Echinococcus multilocularis calpain 0.1164 0.3108 0.3107
Brugia malayi EF hand family protein 0.0182 0.0428 0.0427
Onchocerca volvulus 0.0192 0.0455 0.0738
Schistosoma mansoni lamin 0.0026 0.0001 0.0001
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Leishmania major oligopeptidase b 0.0948 0.2519 0.4089
Echinococcus granulosus neurogenic locus protein delta 0.0027 0.0003 0.0002
Echinococcus granulosus slit 2 protein 0.0027 0.0003 0.0002
Plasmodium falciparum serine repeat antigen 7 0.032 0.0804 0.2341
Brugia malayi Cadherin domain containing protein 0.0027 0.0003 0.0002
Trypanosoma brucei histone deacetylase 4 0.0098 0.0196 0.0307
Toxoplasma gondii hypothetical protein 0.0302 0.0754 0.1222
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0004
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0818 0.0817
Trichomonas vaginalis conserved hypothetical protein 0.032 0.0804 0.2187
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.032 0.0804 0.2341
Entamoeba histolytica histone deacetylase, putative 0.0087 0.0167 0.0469
Onchocerca volvulus Cathepsin L homolog 0.032 0.0804 0.1306
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.004 0.004 0.0096
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0007 0.0008
Echinococcus multilocularis programmed cell death protein 0.0186 0.0438 0.0437
Giardia lamblia Cathepsin B precursor 0.1361 0.3648 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.0804 0.2187
Toxoplasma gondii histone deacetylase HDAC1 0.0098 0.0196 0.0315
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0075 0.0134 0.0133
Echinococcus granulosus gamma secretase subunit aph 1 0.027 0.0668 0.0667
Plasmodium vivax calpain, putative 0.1164 0.3108 0.9116
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0319 0.1167
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0143 0.0322 0.0924
Giardia lamblia Proteasome subunit beta type 3 0.004 0.004 0.0103
Echinococcus multilocularis cysteine protease 0.1274 0.3409 0.3408
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0344 0.0869 0.2366
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.004 0.004 0.0053
Plasmodium falciparum histone deacetylase, putative 0.0098 0.0196 0.0555
Brugia malayi Cathepsin L-like precursor 0.1274 0.3409 0.3408
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0004
Onchocerca volvulus Huntingtin homolog 0.0118 0.0253 0.041
Giardia lamblia Serine peptidase, putative 0.0041 0.0043 0.0111
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.004 0.0039
Mycobacterium ulcerans putative transglutaminase-like protein 0.0285 0.0709 0.2734
Brugia malayi EGF-like domain containing protein 0.0027 0.0003 0.0002
Onchocerca volvulus 0.0031 0.0015 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.004 0.0039
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0025 0.0053
Trypanosoma brucei Aph-1 protein, putative 0.0105 0.0218 0.0342
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0095 1
Trypanosoma brucei centrin, putative 0.0182 0.0428 0.0684
Echinococcus granulosus caspase 2 0.0242 0.0591 0.059
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0095 0.0094
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0186 0.0438 0.0437
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.004 0.004 0.0096
Mycobacterium leprae Probable lipase LipE 0.0075 0.0134 0.038
Echinococcus granulosus protein jagged 1 0.0027 0.0003 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.3702 0.3697
Leishmania major histone deacetylase, putative 0.0087 0.0167 0.026
Brugia malayi Blistered cuticle protein 3 0.0325 0.0818 0.0817
Brugia malayi prolyl oligopeptidase family protein 0.2277 0.615 0.615
Schistosoma mansoni cathepsin F (C01 family) 0.1274 0.3409 0.3409
Giardia lamblia Dipeptidyl-peptidase I precursor 0.032 0.0804 0.2198
Echinococcus multilocularis Regulator of G protein signaling 20 0.0044 0.0049 0.0048
Loa Loa (eye worm) histone deacetylase 7A 0.0098 0.0196 0.0195
Plasmodium vivax centrin-1, putative 0.0182 0.0428 0.1235
Onchocerca volvulus 0.0027 0.0003 0.0002
Leishmania major cathepsin L-like protease 0.1274 0.3409 0.5537
Brugia malayi Trypsin-like protease protein 5 0.0192 0.0455 0.0454
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.027 0.0668 0.0667
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0041 0.0043 0.0105
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0344 0.0869 0.0862
Echinococcus granulosus 20S proteasome subunit alpha 6 0.004 0.004 0.0039
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0044 0.0049 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0049 0.0115
Schistosoma mansoni cathepsin D (A01 family) 0.0233 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.032 0.0804 0.0803
Echinococcus multilocularis histone deacetylase 7 0.0098 0.0196 0.0195
Schistosoma mansoni hypothetical protein 0.0192 0.0455 0.0455
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0052 0.0072 0.0072
Leishmania major C-8 sterol isomerase-like protein 0.0361 0.0915 0.1477
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Loa Loa (eye worm) hypothetical protein 0.0192 0.0455 0.0454
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0455
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0095 0.0094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0332 0.0331
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0249 0.0611 0.167
Giardia lamblia 20S proteasome alpha subunit 4 0.004 0.004 0.0103
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0093 0.0092
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0213 0.0212
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0044 0.0037
Loa Loa (eye worm) proteasome subunit alpha type 3 0.004 0.004 0.0039
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0049 0.0049
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.004 0.0089
Trypanosoma cruzi kinesin, putative 0.082 0.2169 0.2163
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0084 0.0083
Loa Loa (eye worm) cysteine protease 0.1274 0.3409 0.3408
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0332 0.0331
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0003
Trypanosoma cruzi Aph-1 protein, putative 0.0105 0.0218 0.021
Echinococcus granulosus calpain A 0.1164 0.3108 0.3107
Echinococcus granulosus glycoprotein Antigen 5 0.0192 0.0455 0.0454
Schistosoma mansoni hypothetical protein 0.0172 0.0401 0.0401
Brugia malayi hypothetical protein 0.018 0.0422 0.0421
Mycobacterium ulcerans proteasome PrcB 0.0249 0.0611 0.234
Schistosoma mansoni hypothetical protein 0.0285 0.0709 0.0709
Trichomonas vaginalis calpain, putative 0.0344 0.0869 0.2366
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.004 0.0033
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0003 0.0002
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0895 0.2375 0.386
Brugia malayi Histone deacetylase 1 0.0087 0.0167 0.0166
Giardia lamblia Hypothetical protein 0.0185 0.0436 0.1188
Plasmodium vivax vivapain-3 0.0707 0.186 0.5446
Trypanosoma cruzi calmodulin, putative 0.0182 0.0428 0.042
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.004 0.004
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0015 0.0014
Echinococcus granulosus Dipeptidyl peptidase 9 0.0637 0.1669 0.1668
Echinococcus granulosus proteasome subunit beta t family 0.004 0.004 0.0039
Trichomonas vaginalis centrin, putative 0.0182 0.0428 0.1154
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0025 0.0024
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0948 0.2519 0.4089
Brugia malayi Histone deacetylase family protein 0.0098 0.0196 0.0195
Entamoeba histolytica hypothetical protein, conserved 0.0302 0.0754 0.2195
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0994 0.2646 0.264
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0044 0.0049 0.0115
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Brugia malayi Cathepsin L-like cysteine proteinase 0.0887 0.2353 0.2352
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.032 0.0804 0.2341
Brugia malayi hypothetical protein 0.0276 0.0683 0.0682
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0095 0.0094
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0049 0.0049
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.004 0.004 0.0096
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0003
Brugia malayi proteasome subunit beta type 2 0.0091 0.0178 0.0177
Toxoplasma gondii centrin 0.0182 0.0428 0.0691
Giardia lamblia Hypothetical protein 0.032 0.0804 0.2198
Trichomonas vaginalis conserved hypothetical protein 0.0344 0.0869 0.2366
Entamoeba histolytica calmodulin, putative 0.0182 0.0428 0.1235
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0052 0.0071 0.0172
Brugia malayi regulator of G-protein signaling egl-10 0.0044 0.0049 0.0048
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0003 0.0002
Toxoplasma gondii ABC1 family protein 0.0075 0.0134 0.0214
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0134 0.0297 0.0296
Loa Loa (eye worm) Notch2 0.0027 0.0003 0.0002
Trypanosoma cruzi I/6 autoantigen, putative 0.0182 0.0428 0.042
Onchocerca volvulus 0.0056 0.0084 0.0134
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0091 0.0178 0.0469
Giardia lamblia Cathepsin B precursor 0.032 0.0804 0.2198
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0167 0.0438
Loa Loa (eye worm) hypothetical protein 0.032 0.0804 0.0803
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0344 0.0869 0.0862
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0025 0.0018
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0948 0.2519 1
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0071 0.0188
Loa Loa (eye worm) PAS-3 protein 0.004 0.004 0.0039
Echinococcus multilocularis cathepsin b 0.3687 1 1
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Echinococcus multilocularis histone deacetylase 1 0.0087 0.0167 0.0166
Toxoplasma gondii hypothetical protein 0.0031 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0024
Toxoplasma gondii prolyl endopeptidase 0.2277 0.615 1
Echinococcus multilocularis calmodulin 0.0182 0.0428 0.0427
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0186 0.0438 0.0437
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0049 0.0115
Brugia malayi hypothetical protein 0.0043 0.0049 0.0048
Mycobacterium ulcerans proteasome PrcA 0.004 0.004 0.0046
Schistosoma mansoni ap endonuclease 0.006 0.0095 0.0095
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0049 0.0048
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0091 0.0178 0.0278
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1164 0.3108 0.3103
Toxoplasma gondii proteasome subunit 0.004 0.004 0.0061
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.004 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0344 0.0869 0.0862
Echinococcus granulosus calpain A 0.3284 0.89 0.89
Giardia lamblia Cathepsin L precursor 0.032 0.0804 0.2198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.004 0.004 0.0033
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.0319 0.0319
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Onchocerca volvulus Prolyl endopeptidase homolog 0.2277 0.615 1
Schistosoma mansoni inhibitor of apoptosis protein 0.0186 0.0438 0.0438
Toxoplasma gondii microneme protein MIC4 0.0031 0.0015 0.002
Giardia lamblia 20S proteasome alpha subunit 2 0.004 0.004 0.0103
Onchocerca volvulus 0.1274 0.3409 0.5542
Onchocerca volvulus Peroxidasin homolog 0.0325 0.0818 0.1328
Trichomonas vaginalis calmodulin, putative 0.0185 0.0436 0.1176
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.004 0.0089
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Echinococcus multilocularis slit 2 protein 0.0027 0.0003 0.0002
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.004 0.0096
Plasmodium vivax proteasome subunit beta type-5, putative 0.0249 0.0611 0.1775
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0192 0.0455 0.0454
Onchocerca volvulus 0.0027 0.0003 0.0002
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0134 0.0178
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0609 0.0608
Onchocerca volvulus 0.1274 0.3409 0.5542
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Schistosoma mansoni neprilysin 0.0027 0.0004 0.0004
Chlamydia trachomatis glycogen phosphorylase 0.012 0.0257 0.5
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.0103 0.0212 0.0211
Plasmodium falciparum serine repeat antigen 4 0.032 0.0804 0.2341
Toxoplasma gondii calcium-dependent protein kinase 0.0185 0.0436 0.0704
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0192 0.0455 0.0455
Schistosoma mansoni notch 0.0027 0.0003 0.0003
Giardia lamblia Cathepsin B precursor 0.032 0.0804 0.2198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0887 0.2353 0.6442
Schistosoma mansoni hemoglobinase (C13 family) 0.0151 0.0341 0.0341
Echinococcus multilocularis calpain A 0.3284 0.89 0.89
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.004 0.004 0.0096
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.004 0.004 0.0039
Trypanosoma cruzi centrin, putative 0.0186 0.0438 0.0431
Echinococcus granulosus Mastin 0.0192 0.0455 0.0454
Brugia malayi Peptidase family M13 containing protein 0.0103 0.0212 0.0211
Echinococcus granulosus neurogenic locus notch protein 4 0.0027 0.0003 0.0002
Echinococcus granulosus histone deacetylase 0.0098 0.0196 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0103 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.2277 0.615 0.615
Echinococcus multilocularis cysteine protease 0.1274 0.3409 0.3408
Brugia malayi gamma-secretase subunit aph-1 0.027 0.0668 0.0667
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.0611 0.1658
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0249 0.0611 0.2304
Mycobacterium leprae Conserved hypothetical protein 0.0285 0.0709 0.27
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1164 0.3108 0.3103
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0048
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0609 0.0608
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0049 0.0049
Plasmodium falciparum calpain 0.0344 0.0869 0.2533
Mycobacterium ulcerans hypothetical protein 0.0192 0.0455 0.1712
Loa Loa (eye worm) papain family cysteine protease containing protein 0.032 0.0804 0.0803
Entamoeba histolytica calcium binding family protein 0.0182 0.0428 0.1235
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0044 0.0068
Echinococcus granulosus calumenin 0.0185 0.0436 0.0435
Toxoplasma gondii cathepsin CPL 0.1274 0.3409 0.5541
Entamoeba histolytica papain family cysteine protease domain containing protein 0.032 0.0804 0.2341
Entamoeba histolytica proteasome subunit beta type 3, putative 0.004 0.004 0.0096
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0052 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Echinococcus multilocularis hypothetical protein 0.1164 0.3108 0.3107
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.004 0.0033
Onchocerca volvulus Notchless protein homolog 0.004 0.004 0.0063
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0003
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.004 0.004 0.0096
Onchocerca volvulus 0.1274 0.3409 0.5542
Echinococcus multilocularis centrin 2 0.0182 0.0428 0.0427
Echinococcus multilocularis Mastin 0.0192 0.0455 0.0454
Entamoeba histolytica glycogen phosphorylase, putative 0.012 0.0257 0.0735
Plasmodium falciparum histone deacetylase 2 0.0098 0.0196 0.0555
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Toxoplasma gondii troponin c, isotype gamma, putative 0.0182 0.0428 0.0691
Echinococcus multilocularis apoptotic protease activating factor 1 0.018 0.0422 0.0421
Plasmodium falciparum serine repeat antigen 5 0.032 0.0804 0.2341
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Trypanosoma cruzi prolyl endopeptidase 0.2277 0.615 0.6147
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0027 0.0003 0.0002
Echinococcus granulosus cathepsin l1 0.0887 0.2353 0.2352
Entamoeba histolytica cysteine protease, putative 0.032 0.0804 0.2341
Onchocerca volvulus 0.0192 0.0455 0.0738
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.5048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Onchocerca volvulus 0.0031 0.0015 0.0023
Brugia malayi proteasome subunit beta type 3 0.004 0.004 0.0039
Giardia lamblia Cathepsin L-like protease 0.032 0.0804 0.2198
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.0072 0.0072
Echinococcus multilocularis cathepsin b 0.3687 1 1
Brugia malayi Kringle domain containing protein 0.0048 0.0062 0.0061
Trypanosoma brucei proteasome beta 7 subunit 0.004 0.004 0.0053
Trichomonas vaginalis calmodulin, putative 0.0182 0.0428 0.1154
Echinococcus granulosus glycogen phosphorylase 0.012 0.0257 0.0256
Loa Loa (eye worm) hypothetical protein 0.0103 0.0212 0.0211
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Echinococcus multilocularis prolyl endopeptidase 0.2277 0.615 0.615
Echinococcus granulosus proteasome subunit alpha type 2 0.004 0.004 0.0039
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.0182 0.0428 0.0427
Loa Loa (eye worm) hypothetical protein 0.0043 0.0049 0.0048
Brugia malayi Cathepsin L-like precursor 0.1274 0.3409 0.3408
Loa Loa (eye worm) hypothetical protein 0.018 0.0422 0.0421
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0134 0.0424
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Brugia malayi beta-lactamase family protein 0.0075 0.0134 0.0133
Giardia lamblia Alanyl dipeptidyl peptidase 0.0302 0.0754 0.2061
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Loa Loa (eye worm) hypothetical protein 0.0075 0.0134 0.0133
Plasmodium falciparum proteasome subunit beta type-6, putative 0.004 0.004 0.0096
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0948 0.2519 0.2513
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0091 0.0178 0.0502
Loa Loa (eye worm) EF hand family protein 0.0182 0.0428 0.0427
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.004 0.004 0.0033
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0182 0.0428 0.0428
Echinococcus granulosus Regulator of G protein signaling 20 0.0044 0.0049 0.0048
Giardia lamblia Proteasome subunit beta type 1 0.0143 0.0322 0.0875
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0249 0.0611 0.1081
Echinococcus multilocularis caspase 2 0.0242 0.0591 0.059
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3687 1 1
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0004
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.004 0.004 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Schistosoma mansoni histone deacetylase 0.0087 0.0167 0.0167
Schistosoma mansoni calpain-2 (C02 family) 0.0344 0.0869 0.0869
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0249 0.0611 0.0983
Plasmodium vivax proteasome subunit alpha type-7, putative 0.004 0.004 0.0096
Onchocerca volvulus Glycogen phosphorylase homolog 0.012 0.0257 0.0417
Giardia lamblia Cathepsin B precursor 0.032 0.0804 0.2198
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0099 0.02 0.0199
Entamoeba histolytica calpain large subunit domain III containing protein 0.082 0.2169 0.6355
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0142 0.0319 0.0318
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Plasmodium vivax plasmepsin IV, putative 0.0043 0.0049 0.0121
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1274 0.3409 0.3408
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0895 0.2375 0.2375
Plasmodium falciparum plasmepsin V 0.0043 0.0049 0.0121
Plasmodium vivax SET domain protein, putative 0.0103 0.0212 0.0602
Loa Loa (eye worm) hypothetical protein 0.0103 0.0212 0.0211
Brugia malayi A-kinase anchor protein 10, precursor 0.0044 0.0049 0.0048
Giardia lamblia Cysteine protease 0.032 0.0804 0.2198
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0003 0.0002
Schistosoma mansoni centrin 0.0182 0.0428 0.0428
Entamoeba histolytica cysteine proteinase, putative 0.1274 0.3409 1
Entamoeba histolytica calcium-binding protein, putative 0.0182 0.0428 0.1235
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0134 0.0133
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0095 0.0104
Echinococcus multilocularis proteasome subunit alpha type 2 0.004 0.004 0.0039
Trypanosoma brucei metacaspase MCA3 0.0062 0.0099 0.0149
Plasmodium vivax proteasome subunit alpha type-2, putative 0.004 0.004 0.0096
Schistosoma mansoni ap endonuclease 0.006 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0344 0.0869 0.0868
Trypanosoma brucei Calpain-like protein 1.1 0.0344 0.0869 0.1402
Brugia malayi Cell death protein 3 precursor 0.0242 0.0591 0.059
Brugia malayi Ets-domain containing protein 0.0073 0.0129 0.0128
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0895 0.2375 0.2374
Loa Loa (eye worm) calmodulin-like protein 0.0182 0.0428 0.0427
Loa Loa (eye worm) hypothetical protein 0.0192 0.0455 0.0454
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0062 0.0099 0.0157
Echinococcus multilocularis enteropeptidase 0.0192 0.0455 0.0454
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.3702 0.3697
Echinococcus multilocularis calbindin 32 0.0185 0.0436 0.0435
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0044 0.0044
Plasmodium falciparum proteasome subunit beta type-4 0.004 0.004 0.0096
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0103 0.0212 0.0211
Trichomonas vaginalis calmodulin, putative 0.0182 0.0428 0.1154
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0249 0.0611 0.1775
Echinococcus multilocularis proteasome subunit beta type 6 0.004 0.004 0.0039
Echinococcus granulosus protein jagged 1 0.0027 0.0003 0.0002
Trichomonas vaginalis calmodulin, putative 0.0182 0.0428 0.1154
Onchocerca volvulus 0.1274 0.3409 0.5542
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0091 0.0178 0.0469
Echinococcus multilocularis notch 0.0027 0.0003 0.0002
Plasmodium falciparum serine repeat antigen 1 0.032 0.0804 0.2341
Trichomonas vaginalis calmodulin, putative 0.0182 0.0428 0.1154
Trichomonas vaginalis calpain, putative 0.0344 0.0869 0.2366
Toxoplasma gondii proteasome subunit alpha type, putative 0.004 0.004 0.0061
Echinococcus multilocularis calcium uptake protein 1 0.0185 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Onchocerca volvulus Dual oxidase homolog 0.0325 0.0818 0.1328
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0071 0.0188
Plasmodium vivax metacaspase 1, putative 0.0062 0.0099 0.0269
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0129 0.0128
Trichomonas vaginalis glycogen phosphorylase, putative 0.012 0.0257 0.0686
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.004 0.004 0.0061
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0043 0.0049 0.0075
Echinococcus multilocularis EF hand domain containing family member A2 0.0185 0.0436 0.0435
Trypanosoma brucei proteasome beta 2 subunit, putative 0.004 0.004 0.0053
Echinococcus multilocularis geminin 0.0172 0.0401 0.04
Trypanosoma cruzi Aph-1 protein, putative 0.0105 0.0218 0.021
Trypanosoma brucei Calpain-like protein 1.2 0.0344 0.0869 0.1402
Echinococcus granulosus calbindin 32 0.0185 0.0436 0.0435
Entamoeba histolytica glycogen phosphorylase, putative 0.012 0.0257 0.0735
Onchocerca volvulus 0.0031 0.0015 0.0023
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0041 0.0043 0.0105
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.004 0.0039
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.5048
Leishmania major cathepsin L-like protease 0.1274 0.3409 0.5537
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0185 0.0436 0.0428
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0302 0.0754 0.1222
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0095 0.0088
Toxoplasma gondii PAN/Apple domain-containing protein 0.0031 0.0015 0.002
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0044 0.0049 0.0048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.3103
Schistosoma mansoni hypothetical protein 0.0172 0.0401 0.0401
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.004 0.004 0.0096
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1274 0.3409 0.3408
Giardia lamblia Alanyl dipeptidyl peptidase 0.0302 0.0754 0.2061
Mycobacterium tuberculosis Conserved protein 0.0075 0.0134 0.0178
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.5048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Trypanosoma cruzi hypothetical protein, conserved 0.0302 0.0754 0.0747
Onchocerca volvulus 0.0174 0.0406 0.0658
Plasmodium vivax proteasome subunit alpha type-5, putative 0.004 0.004 0.0096
Leishmania major histone deacetylase, putative 0.0087 0.0167 0.026
Schistosoma mansoni cell polarity protein 0.0027 0.0003 0.0003
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0049 0.0048
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0637 0.1669 0.2705
Trypanosoma cruzi metacaspase, putative 0.0062 0.0099 0.0092
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0529 0.1376 0.2233
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0771 0.2037 0.2036
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0049 0.0048
Schistosoma mansoni hemoglobinase (C13 family) 0.0151 0.0341 0.0341
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.004 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.032 0.0804 0.2187
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0344 0.0869 0.0862
Trypanosoma cruzi conserved protein 0.0344 0.0869 0.0862
Plasmodium vivax aspartyl protease, putative 0.0206 0.0493 0.1426
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0143 0.0322 0.0863
Leishmania major proteasome beta 7 subunit, putative 0.004 0.004 0.0053
Trichomonas vaginalis calmodulin-2, putative 0.0182 0.0428 0.1154
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0344 0.0869 0.2366
Plasmodium vivax aspartyl protease, putative 0.0043 0.0049 0.0121
Brugia malayi hypothetical protein 0.0174 0.0406 0.0405
Schistosoma mansoni hypothetical protein 0.0186 0.0438 0.0438
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0182 0.0428 0.042
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Loa Loa (eye worm) proteasome subunit alpha type 6 0.004 0.004 0.0039
Brugia malayi proteasome subunit alpha type 3 0.004 0.004 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0302 0.0754 0.0747
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Trypanosoma cruzi cysteine peptidase, putative 0.1274 0.3409 0.3404
Trypanosoma brucei kinesin, putative 0.082 0.2169 0.3519
Trichomonas vaginalis calcium binding proteins, putative 0.0182 0.0428 0.1154
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3687 1 1
Onchocerca volvulus Chorion peroxidase homolog 0.0325 0.0818 0.1328
Schistosoma mansoni reticulocalbin 0.0182 0.0428 0.0428
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1361 0.3648 0.3643
Onchocerca volvulus 0.0048 0.0062 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Brugia malayi regulator of G-protein signaling rgs-7 0.0044 0.0049 0.0048
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0361 0.0915 0.0914
Leishmania major centrin, putative,caltractin, putative 0.0182 0.0428 0.0684
Loa Loa (eye worm) PXA domain-containing protein 0.0044 0.0049 0.0048
Trypanosoma brucei centrin, putative 0.0182 0.0428 0.0684
Schistosoma mansoni notch 0.0027 0.0003 0.0003
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.004 0.004
Giardia lamblia 20S proteasome alpha subunit 7 0.004 0.004 0.0103
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0182 0.0428 0.042
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0249 0.0611 0.061
Plasmodium falciparum serine repeat antigen 9 0.032 0.0804 0.2341
Echinococcus multilocularis calpain family protein 1, d 0.2279 0.6155 0.6155
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0091 0.0178 0.0177
Echinococcus multilocularis neurogenic locus notch protein 4 0.0027 0.0003 0.0002
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0428 0.0428
Brugia malayi cathepsin L precursor 0.032 0.0804 0.0803
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0771 0.2037 0.2036
Plasmodium falciparum plasmepsin VI 0.0043 0.0049 0.0121
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1274 0.3409 1
Brugia malayi Serine protease Z688.6 precursor 0.0041 0.0043 0.0042
Loa Loa (eye worm) fibroinase 0.1274 0.3409 0.3408
Toxoplasma gondii subtilisin SUB12 0.0031 0.0015 0.002
Plasmodium falciparum centrin-1 0.0182 0.0428 0.1235
Trypanosoma cruzi oligopeptidase b 0.0948 0.2519 0.2513
Brugia malayi histone deacetylase 11 0.0042 0.0044 0.0043
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0151 0.0341 0.0917
Echinococcus granulosus delta-like protein 1 0.0027 0.0003 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0015 0.002
Schistosoma mansoni hypothetical protein 0.0048 0.0062 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0707 0.186 0.5088
Onchocerca volvulus Deterin homolog 0.0186 0.0438 0.071
Brugia malayi MH2 domain containing protein 0.0249 0.0609 0.0608
Toxoplasma gondii proteasome subunit alpha1, putative 0.004 0.004 0.0061
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0043 0.0049 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.0804 0.2187
Trichomonas vaginalis calmodulin, putative 0.0182 0.0428 0.1154
Schistosoma mansoni glycogen phosphorylase 0.012 0.0257 0.0257
Entamoeba histolytica hypothetical protein 0.0044 0.0049 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.3103
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0044 0.0043
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.004 0.0033
Giardia lamblia Transglutaminase/protease, putative 0.0285 0.0709 0.1939
Brugia malayi notch-like transmembrane receptor 0.0027 0.0003 0.0002
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.004 0.004 0.004
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0344 0.0869 0.1402
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0134 0.0348
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.004 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0098
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0185 0.0436 0.0436
Plasmodium falciparum cysteine repeat modular protein 1 0.0048 0.0062 0.0159
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Giardia lamblia 20S proteasome alpha subunit 3 0.004 0.004 0.0103
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0249 0.0611 0.0604
Brugia malayi Cathepsin L-like precursor 0.0387 0.0986 0.0985
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0049 0.0049
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.032 0.0804 0.2341
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0116 0.0184
Schistosoma mansoni cathepsin F (C01 family) 0.1274 0.3409 0.3409
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1361 0.3648 0.3648
Echinococcus granulosus calpain 7 C02 family 0.1164 0.3108 0.3107
Brugia malayi Pre-SET motif family protein 0.0103 0.0212 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0134 0.0178
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.004 0.0033
Trypanosoma brucei mitochondrial calcium uptake 1 0.0182 0.0428 0.0684
Onchocerca volvulus 0.0325 0.0818 0.1328
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Leishmania major calmodulin-like protein 0.0182 0.0428 0.0684
Echinococcus multilocularis inhibitor of apoptosis protein 0.0186 0.0438 0.0437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.0804 0.2187
Schistosoma mansoni hypothetical protein 0.0116 0.0246 0.0246
Toxoplasma gondii exonuclease III APE 0.006 0.0095 0.015
Echinococcus granulosus histone deacetylase 3 0.0087 0.0167 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1274 0.3409 0.9343
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.004 0.0033
Brugia malayi EGF-like domain containing protein 0.0027 0.0003 0.0002
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Echinococcus multilocularis endothelin converting enzyme 1 0.0103 0.0212 0.0211
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.004 0.0039
Echinococcus multilocularis calpain 5 0.1164 0.3108 0.3107
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0134 0.0348
Brugia malayi Papain family cysteine protease containing protein 0.032 0.0804 0.0803
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.004 0.004 0.0096
Plasmodium vivax serine-repeat antigen (SERA), putative 0.032 0.0804 0.2341
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.032 0.0804 0.2341
Brugia malayi proteasome subunit beta type 1 0.0143 0.0322 0.0321
Trichomonas vaginalis myosin light chain 1, putative 0.0182 0.0428 0.1154
Trypanosoma brucei ATP-dependent protease subunit HslV 0.004 0.004 0.0053
Toxoplasma gondii EFHC1, putative 0.0182 0.0428 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0428 0.1154
Plasmodium falciparum proteasome subunit beta type-3, putative 0.004 0.004 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0302 0.0754 0.205
Brugia malayi histone deacetylase 3 (HD3) 0.0087 0.0167 0.0166
Mycobacterium leprae probable zinc metalloprotease 0.0103 0.0212 0.0694
Loa Loa (eye worm) hypothetical protein 0.0276 0.0683 0.0682
Loa Loa (eye worm) programmed cell death protein 6 0.0185 0.0436 0.0435
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0048
Echinococcus granulosus inhibitor of apoptosis protein 0.0186 0.0438 0.0437
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Onchocerca volvulus 0.0887 0.2353 0.3825
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0167 0.016
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2277 0.615 0.615
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0091 0.0178 0.0286
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0428 0.1154
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.3281 0.8892 0.8892
Onchocerca volvulus 0.0325 0.0818 0.1328
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.032 0.0804 0.2187
Onchocerca volvulus Cathepsin F homolog 0.1274 0.3409 0.5542
Loa Loa (eye worm) peptidase family M13 containing protein 0.0076 0.0138 0.0137
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.032 0.0804 0.0803
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0332 0.0332
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Leishmania major cysteine peptidase A (CPA) 0.1274 0.3409 0.5537
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0025 0.0037
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Echinococcus granulosus endothelin converting enzyme 1 0.0103 0.0212 0.0211
Loa Loa (eye worm) hypothetical protein 0.0192 0.0455 0.0454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Entamoeba histolytica grainin 2 0.0186 0.0438 0.1265
Loa Loa (eye worm) histone deacetylase 3 0.0087 0.0167 0.0166
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0095 0.5
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0014
Echinococcus granulosus cathepsin b 0.3687 1 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0167 0.0438
Echinococcus granulosus microtubule associated protein 2 0.1592 0.4279 0.4278
Giardia lamblia Hypothetical protein 0.032 0.0804 0.2198
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0014
Echinococcus multilocularis EF hand domain containing family member A2 0.0182 0.0428 0.0427
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0818 0.0817
Echinococcus multilocularis tumor protein p63 0.039 0.0994 0.0993
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0098
Entamoeba histolytica cysteine protease, putative 0.032 0.0804 0.2341
Echinococcus granulosus cathepsin l1 0.1274 0.3409 0.3408
Entamoeba histolytica calpain family cysteine protease, putative 0.0344 0.0869 0.2533
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0428 0.0428
Trichomonas vaginalis esterase, putative 0.0075 0.0134 0.0348
Giardia lamblia Cathepsin L-like protease 0.032 0.0804 0.2198
Echinococcus granulosus histone deacetylase 1 0.0087 0.0167 0.0166
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0716 0.1886 0.1885
Onchocerca volvulus 0.0034 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.2755 0.7455 0.7455
Leishmania major proteasome beta 5 subunit, putative 0.0249 0.0611 0.0983
Brugia malayi cathepsin F-like cysteine proteinase 0.0387 0.0986 0.0985
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Brugia malayi hypothetical protein 0.0043 0.0049 0.0048
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0387 0.0986 0.0985
Onchocerca volvulus Cathepsin L homolog 0.1274 0.3409 0.5542
Trypanosoma cruzi cruzipain precursor, putative 0.1381 0.3702 0.3697
Leishmania major calcineurin B subunit, putative 0.0182 0.0428 0.0684
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0332 0.0331
Schistosoma mansoni reticulocalbin 0.0185 0.0436 0.0436
Plasmodium vivax proteasome subunit alpha type-3, putative 0.004 0.004 0.0096
Entamoeba histolytica prolyl oligopeptidase family protein 0.0302 0.0754 0.2195
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0302 0.0754 0.205
Brugia malayi hypothetical protein 0.0228 0.0552 0.0551
Plasmodium falciparum peptidase, putative 0.0302 0.0754 0.2195
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0142 0.0319 0.0528
Echinococcus multilocularis Transglutaminase 0.0285 0.0709 0.0708
Entamoeba histolytica cysteine proteinase, putative 0.0707 0.186 0.5446
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0048
Mycobacterium ulcerans beta-lactamase 0.0075 0.0134 0.0424
Brugia malayi Trypsin family protein 0.0192 0.0455 0.0454
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0007 0.0013
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0049 0.0048
Echinococcus granulosus dnaJ subfamily B 0.0483 0.1248 0.1247
Echinococcus multilocularis Proteasome, subunit alpha beta 0.004 0.004 0.0039
Trypanosoma cruzi major cysteine proteinase, putative 0.0427 0.1097 0.109
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0428 0.0428
Trypanosoma cruzi cysteine proteinase, putative 0.0707 0.186 0.1854
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0182 0.0428 0.0684
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Entamoeba histolytica grainin, putative 0.0185 0.0436 0.1259
Toxoplasma gondii aldehyde dehydrogenase 0.0142 0.0319 0.0515
Echinococcus granulosus proteasome prosome macropain 0.0249 0.0611 0.061
Toxoplasma gondii hypothetical protein 0.0344 0.0869 0.1409
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0302 0.0754 0.1215
Giardia lamblia Cysteine protease 0.032 0.0804 0.2198
Echinococcus granulosus neural cadherin 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0302 0.0754 0.0753
Onchocerca volvulus Slit protein homolog 0.0027 0.0003 0.0002
Echinococcus multilocularis cpg binding protein 0.0036 0.0028 0.0027
Trichomonas vaginalis calcium binding protein, putative 0.0186 0.0438 0.1182
Mycobacterium tuberculosis Conserved protein 0.0075 0.0134 0.0178
Leishmania major calmodulin, putative 0.0182 0.0428 0.0684
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1164 0.3108 0.3103
Loa Loa (eye worm) calpain family protein 1 0.3099 0.8394 0.8394
Leishmania major phospholipase c-like protein 0.0182 0.0428 0.0684
Leishmania major cathepsin L-like protease 0.1274 0.3409 0.5537
Echinococcus granulosus caspase 8 0.0062 0.0099 0.0098
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1361 0.3648 0.5927
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.004 0.0033
Schistosoma mansoni calpain-7 (C02 family) 0.1167 0.3116 0.3116
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0027 0.0003 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.004 0.0053
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0041 0.0043 0.0098
Trypanosoma cruzi histone deacetylase 1, putative 0.0087 0.0167 0.016
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.0887 0.2353 0.2352
Brugia malayi Trypsin family protein 0.0192 0.0455 0.0454
Plasmodium vivax histone deacetylase, putative 0.0098 0.0196 0.0555
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.004 0.004 0.0096
Trichomonas vaginalis glycogen phosphorylase, putative 0.012 0.0257 0.0686
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Schistosoma mansoni hypothetical protein 0.0182 0.0428 0.0428
Toxoplasma gondii proteasome subunit beta type, putative 0.0249 0.0611 0.099
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0086 0.0086
Leishmania major programmed cell death 6 protein-like protein 0.0182 0.0428 0.0684
Plasmodium falciparum serine repeat antigen 2 0.032 0.0804 0.2341
Brugia malayi Cathepsin L-like precursor 0.1274 0.3409 0.3408
Loa Loa (eye worm) trypsin family protein 0.0192 0.0455 0.0454
Onchocerca volvulus 0.0192 0.0455 0.0738
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0043 0.0049 0.0075
Loa Loa (eye worm) hypothetical protein 0.0174 0.0406 0.0405
Trypanosoma cruzi calmodulin, putative 0.0182 0.0428 0.042
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.004 0.0096
Brugia malayi 20S proteasome alpha5 subunit 0.004 0.004 0.0039
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Onchocerca volvulus 0.0031 0.0015 0.0023
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0302 0.0754 0.2195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0707 0.186 0.3016
Brugia malayi cathepsin Z-like cysteine proteinase 0.032 0.0804 0.0803
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0095 0.0254
Onchocerca volvulus 0.0192 0.0455 0.0738
Loa Loa (eye worm) aspartyl protease 6 0.0043 0.0049 0.0048
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0637 0.1669 0.1669
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0044 0.0049 0.0048
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0041 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0048
Onchocerca volvulus 0.0057 0.0086 0.0138
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Schistosoma mansoni z-protein (S1r protein) 0.0044 0.0049 0.0049
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0182 0.0428 0.0427
Loa Loa (eye worm) hypothetical protein 0.0043 0.0049 0.0048
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.032 0.0804 0.2341
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.0683 0.0682
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0182 0.0428 0.1235
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.3103
Echinococcus multilocularis cathepsin L cysteine protease 0.1274 0.3409 0.3408
Plasmodium falciparum proteasome subunit beta type-7, putative 0.004 0.004 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.0804 0.2187
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0029 0.0021
Plasmodium vivax unspecified product 0.032 0.0804 0.2341
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0344 0.0869 0.1402
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.0804 0.2187
Loa Loa (eye worm) histone deacetylase 0.0098 0.0196 0.0195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.004 0.004 0.0033
Entamoeba histolytica calmodulin, putative 0.0182 0.0428 0.1235
Brugia malayi Pepsin A precursor 0.0043 0.0049 0.0048
Brugia malayi Thioredoxin family protein 0.0285 0.0709 0.0708
Schistosoma mansoni peroxidasin 0.0325 0.0818 0.0818
Echinococcus granulosus Proteasome subunit alpha type 7 0.004 0.004 0.0039
Onchocerca volvulus 0.0815 0.2157 0.3506
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Leishmania major centrin, putative 0.0182 0.0428 0.0684
Schistosoma mansoni histone deacetylase hda2 0.0104 0.0213 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.0804 0.2187
Loa Loa (eye worm) TK/ROR protein kinase 0.0048 0.0062 0.0061
Giardia lamblia 20S proteasome alpha subunit 1 0.004 0.004 0.0103
Loa Loa (eye worm) hypothetical protein 0.0409 0.1048 0.1047
Trypanosoma brucei calpain, putative 0.0344 0.0869 0.1402
Loa Loa (eye worm) hypothetical protein 0.0078 0.0143 0.0142
Echinococcus granulosus histone lysine methyltransferase setb 0.0103 0.0212 0.0211
Entamoeba histolytica cysteine proteinase 2 0.0707 0.186 0.5446
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0143 0.0322 0.0322
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0186 0.0438 0.0437
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.004 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0344 0.0869 0.0862
Leishmania major calpain family cysteine protease-like protein 0.0344 0.0869 0.1402
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0099 0.0252
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Plasmodium vivax proteasome subunit beta type-1, putative 0.0143 0.0322 0.0924
Giardia lamblia Histone deacetylase 0.0087 0.0167 0.0451
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0637 0.1669 0.2705
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0344 0.0869 0.2366
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0003 0.0002
Onchocerca volvulus 0.0043 0.0049 0.0077
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.004 0.004 0.004
Trypanosoma brucei hypothetical protein 0.0344 0.0869 0.1402
Schistosoma mansoni calpain-7 (C02 family) 0.1167 0.3116 0.3116
Echinococcus multilocularis caspase 8 0.0062 0.0099 0.0098
Schistosoma mansoni peroxidasin 0.0325 0.0818 0.0818
Trypanosoma brucei calpain-like protein, putative 0.1164 0.3108 0.5048
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.004 0.004
Mycobacterium ulcerans lipase LipD 0.0075 0.0134 0.0424
Echinococcus multilocularis protein jagged 1 0.0027 0.0003 0.0002
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0707 0.186 0.186
Brugia malayi PXA domain containing protein 0.0044 0.0049 0.0048
Echinococcus multilocularis Glycosyl transferase, family 35 0.012 0.0257 0.0256
Trypanosoma cruzi centrin, putative 0.0186 0.0438 0.0431
Trypanosoma cruzi 20S proteasome subunit 0.0091 0.0178 0.0171
Onchocerca volvulus 0.0186 0.0438 0.071
Echinococcus multilocularis histone deacetylase 3 0.0087 0.0167 0.0166
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Echinococcus multilocularis protein jagged 1 0.0027 0.0003 0.0002
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Entamoeba histolytica hypothetical protein 0.0044 0.0049 0.0123
Echinococcus granulosus cathepsin L 0.0707 0.186 0.1859
Leishmania major hypothetical protein, conserved 0.0182 0.0428 0.0684
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0186 0.0438 0.0437
Loa Loa (eye worm) proteasome subunit alpha type 2 0.004 0.004 0.0039
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2277 0.615 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.5048
Plasmodium vivax proteasome subunit alpha type-4, putative 0.004 0.004 0.0096
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0134 0.0206
Leishmania major calpain protease-like protein 0.0344 0.0869 0.1402
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0025 0.0025
Plasmodium vivax proteasome subunit beta type-3, putative 0.004 0.004 0.0096
Brugia malayi Ets-domain containing protein 0.0073 0.0129 0.0128
Giardia lamblia Cathepsin L precursor 0.032 0.0804 0.2198
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0042
Trypanosoma brucei protein I/6 0.0182 0.0428 0.0684
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0167 0.0438
Loa Loa (eye worm) beta-lactamase 0.0075 0.0134 0.0133
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2277 0.615 0.615
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0041 0.0043 0.0105
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.004 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.1274 0.3409 0.3408
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.004 0.0089
Loa Loa (eye worm) histone deacetylase 1 0.0087 0.0167 0.0166
Schistosoma mansoni cpg binding protein 0.0036 0.0028 0.0028
Trypanosoma brucei Component of motile flagella 41 0.0182 0.0428 0.0684
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0948 0.2519 1
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0044 0.007
Toxoplasma gondii histone deacetylase HDAC3 0.0087 0.0167 0.0268
Plasmodium falciparum plasmepsin VIII, putative 0.0043 0.0049 0.0121
Loa Loa (eye worm) prolyl oligopeptidase 0.0895 0.2375 0.2374
Plasmodium vivax serine-repeat antigen (SERA), putative 0.032 0.0804 0.2341
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.004 0.004 0.0053
Schistosoma mansoni cathepsin B (C01 family) 0.032 0.0804 0.0804
Leishmania major proteasome beta 3 subunit, putative 0.004 0.004 0.0053
Plasmodium falciparum cysteine proteinase falcipain 3 0.1274 0.3409 1
Mycobacterium leprae Conserved hypothetical protein 0.0285 0.0709 0.27
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3281 0.8892 0.8892
Toxoplasma gondii microneme protein MIC17C 0.0031 0.0015 0.002
Giardia lamblia Cathepsin L precursor 0.032 0.0804 0.2198
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0041 0.0043 0.0066
Echinococcus multilocularis caspase 3 0.0072 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.0804 0.0804
Brugia malayi beta-lactamase 0.0075 0.0134 0.0133
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Onchocerca volvulus Cathepsin L homolog 0.1274 0.3409 0.5542
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0015 0.0014
Schistosoma mansoni notch 0.0027 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Onchocerca volvulus 0.0075 0.0134 0.0216
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0637 0.1669 0.1663
Brugia malayi PXA domain containing protein 0.0044 0.0049 0.0048
Echinococcus multilocularis calmodulin 0.0182 0.0428 0.0427
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0344 0.0869 0.0862
Schistosoma mansoni hypothetical protein 0.0344 0.0869 0.0869
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0015 0.002
Trypanosoma brucei histone deacetylase, putative 0.0098 0.0196 0.0307
Echinococcus multilocularis gamma secretase subunit aph 1 0.027 0.0668 0.0667
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0134 0.0424
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0095 0.0241
Trichomonas vaginalis calmodulin, putative 0.0182 0.0428 0.1154
Brugia malayi calpain family protein 1 0.3099 0.8394 0.8394
Toxoplasma gondii preprocathepsin c precursor, putative 0.032 0.0804 0.1303
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0025 0.0029
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.004 0.004 0.0039
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0043 0.0049 0.0048
Echinococcus granulosus caspase 0.0134 0.0297 0.0296
Entamoeba histolytica cysteine proteinase 1, putative 0.0707 0.186 0.5446
Entamoeba histolytica cysteine proteinase, putative 0.1274 0.3409 1
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0818 0.0817
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0478 0.1235 0.226
Trypanosoma brucei Calpain-like protein 2 0.0344 0.0869 0.1402
Giardia lamblia Proteasome subunit beta type 7 precursor 0.004 0.004 0.0103
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0029 0.0021
Trypanosoma brucei histone deacetylase 3 0.0098 0.0196 0.0307
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0015 0.002
Leishmania major metacaspase, putative 0.0062 0.0099 0.0149
Brugia malayi cathepsin L-like cysteine proteinase 0.032 0.0804 0.0803
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.004 0.004 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.0804 0.0804
Brugia malayi Cathepsin L-like precursor 0.1274 0.3409 0.3408
Onchocerca volvulus 0.018 0.0422 0.0685
Echinococcus multilocularis transmembrane protease serine 3 0.0192 0.0455 0.0454
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.004 0.004 0.0096
Onchocerca volvulus 0.0051 0.007 0.0112
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0062 0.0099 0.0098
Giardia lamblia Encystation-specific protease 0.032 0.0804 0.2198
Plasmodium vivax histone deacetylase, putative 0.0042 0.0044 0.0108
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0043 0.0049 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1361 0.3648 1
Echinococcus granulosus tumor protein p63 0.039 0.0994 0.0993
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0095 0.0267
Loa Loa (eye worm) prolyl oligopeptidase 0.0302 0.0754 0.0753
Plasmodium vivax vivapain-2 0.1274 0.3409 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0143 0.0142
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.004 0.0033
Schistosoma mansoni neprilysin-2 (M13 family) 0.0052 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0003 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.0212 0.0212
Plasmodium vivax proteasome subunit beta type-2, putative 0.0091 0.0178 0.0502
Brugia malayi aspartic protease BmAsp-2, identical 0.0043 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0042
Loa Loa (eye worm) calpain D 0.0344 0.0869 0.0868
Plasmodium vivax serine-repeat antigen (SERA) 0.032 0.0804 0.2341
Schistosoma mansoni septate junction protein 0.0027 0.0003 0.0003
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0707 0.186 0.186
Trypanosoma cruzi calmodulin, putative 0.0182 0.0428 0.042
Trypanosoma cruzi cysteine protease, putative 0.0707 0.186 0.1854
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0344 0.0869 0.0862
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Leishmania major histone deacetylase, putative 0.0098 0.0196 0.0307
Leishmania major kinesin, putative 0.082 0.2169 0.3519
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0344 0.0869 0.2366
Entamoeba histolytica hypothetical protein, conserved 0.0185 0.0436 0.1259
Entamoeba histolytica cysteine protease, putative 0.032 0.0804 0.2341
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.032 0.0804 0.0804
Onchocerca volvulus 0.0031 0.0015 0.0023
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0249 0.0611 0.0604
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0151 0.0341 0.0917
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.004 0.004 0.0053
Entamoeba histolytica hypothetical protein 0.032 0.0804 0.2341
Loa Loa (eye worm) hypothetical protein 0.0242 0.0591 0.059
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Loa Loa (eye worm) hypothetical protein 0.0076 0.0138 0.0137
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.004 0.0039
Trypanosoma brucei proteasome beta 6 subunit 0.0143 0.0322 0.0512
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.004 0.0053
Plasmodium falciparum metacaspase 1 0.0062 0.0099 0.0269
Brugia malayi calpain 7 0.1164 0.3108 0.3107
Loa Loa (eye worm) hypothetical protein 0.0387 0.0986 0.0985
Plasmodium vivax proteasome subunit alpha type-6, putative 0.004 0.004 0.0096
Onchocerca volvulus 0.0031 0.0015 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0025 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0099 0.0252
Echinococcus granulosus histone deacetylase 6 0.0098 0.0196 0.0195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Schistosoma mansoni neuronal calcium sensor 0.0182 0.0428 0.0428
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.004 0.0089
Onchocerca volvulus Peroxidasin homolog 0.0325 0.0818 0.1328
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0099 0.0252
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0099 0.0269
Leishmania major proteasome beta 2 subunit, putative 0.0091 0.0178 0.0278
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0302 0.0754 0.205
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0142 0.0319 0.0318
Giardia lamblia Cathepsin B precursor 0.1361 0.3648 1
Giardia lamblia Glycogen phosphorylase 0.012 0.0257 0.0699
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Brugia malayi hypothetical protein 0.0044 0.0049 0.0048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Loa Loa (eye worm) hypothetical protein 0.0887 0.2353 0.2352
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0049 0.0049
Brugia malayi Proteasome subunit alpha type 1 0.004 0.004 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Echinococcus multilocularis proteasome (prosome, macropain) 0.0249 0.0611 0.061
Trypanosoma brucei calpain-like protein, putative 0.1164 0.3108 0.5048
Mycobacterium tuberculosis Long conserved protein 0.0285 0.0709 0.1266
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0044 0.0044
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0454
Brugia malayi Papain family cysteine protease containing protein 0.0707 0.186 0.1859
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.3702 0.3697
Leishmania major hypothetical protein, unknown function 0.0344 0.0869 0.1402
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0103 0.0212 0.0326
Onchocerca volvulus 0.0103 0.0212 0.0343
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0134 0.0133
Brugia malayi cathepsin F-like cysteine proteinase 0.032 0.0804 0.0803
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Echinococcus multilocularis fat cadherin tumor suppressor 0.0027 0.0003 0.0002
Toxoplasma gondii peptidase, T1 family protein 0.004 0.004 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1274 0.3409 0.9343
Schistosoma mansoni histone deacetylase 0.0087 0.0167 0.0167
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0182 0.0428 0.042
Schistosoma mansoni memapsin-2 (A01 family) 0.0532 0.1383 0.1383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Plasmodium vivax proteasome subunit beta type-4, putative 0.004 0.004 0.0096
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.004 0.004 0.004
Brugia malayi cahepsin L-like non-peptiedase homolog 0.032 0.0804 0.0803
Trypanosoma brucei calpain-like protein, putative 0.1164 0.3108 0.5048
Onchocerca volvulus 0.0031 0.0015 0.0023
Loa Loa (eye worm) hypothetical protein 0.0076 0.0138 0.0137
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.0022 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Giardia lamblia Hypothetical protein 0.0285 0.0709 0.1939
Schistosoma mansoni hypothetical protein 0.0182 0.0428 0.0428
Echinococcus granulosus cysteine protease 0.0707 0.186 0.1859
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0044 0.0049 0.0048
Echinococcus multilocularis microtubule associated protein 2 0.1592 0.4279 0.4278
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0025 0.0049
Toxoplasma gondii EF hand domain-containing protein 0.0182 0.0428 0.0691
Toxoplasma gondii aspartyl protease ASP1 0.0043 0.0049 0.0075
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0361 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Echinococcus granulosus calcium uptake protein 1 0.0185 0.0436 0.0435
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.004 0.004 0.0039
Plasmodium vivax hypothetical protein, conserved 0.0185 0.0436 0.1259
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Onchocerca volvulus 0.0027 0.0003 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0455
Trichomonas vaginalis calcium binding protein, putative 0.0182 0.0428 0.1154
Plasmodium falciparum plasmepsin I 0.0043 0.0049 0.0121
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0007 0.0006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.032 0.0804 0.2341
Echinococcus multilocularis glycoprotein Antigen 5 0.0192 0.0455 0.0454
Trypanosoma brucei histone deacetylase 1 0.0087 0.0167 0.026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Echinococcus granulosus proteasome subunit beta type 6 0.004 0.004 0.0039
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0249 0.0611 0.0611
Brugia malayi Cadherin domain containing protein 0.0027 0.0003 0.0002
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3687 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.0804 0.2187
Leishmania major hypothetical protein, conserved 0.0075 0.0134 0.0206
Echinococcus multilocularis calumenin 0.0185 0.0436 0.0435
Leishmania major cathepsin L-like protease 0.1274 0.3409 0.5537
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0007 0.0006
Plasmodium falciparum plasmepsin III 0.0043 0.0049 0.0121
Plasmodium falciparum cysteine proteinase falcipain 1 0.0707 0.186 0.5446
Leishmania major proteasome alpha 3 subunit, putative 0.004 0.004 0.0053
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0151 0.0341 0.0917
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.032 0.0804 0.2341
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Loa Loa (eye worm) hypothetical protein 0.0887 0.2353 0.2352
Plasmodium vivax histone deacetylase 1, putative 0.0087 0.0167 0.0469
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0103 0.0212 0.0341
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0182 0.0428 0.0684
Loa Loa (eye worm) hypothetical protein 0.032 0.0804 0.0803
Echinococcus multilocularis cathepsin L 0.0707 0.186 0.1859
Entamoeba histolytica cysteine proteinase, putative 0.0707 0.186 0.5446
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0344 0.0869 0.2366
Echinococcus granulosus geminin 0.0172 0.0401 0.04
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0167 0.0438
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Leishmania major proteasome beta 2 subunit, putative 0.004 0.004 0.0053
Onchocerca volvulus 0.0031 0.0015 0.0023
Loa Loa (eye worm) peptidase C13 family protein 0.0151 0.0341 0.034
Brugia malayi calpain D 0.0344 0.0869 0.0868
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0015 0.0014
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Plasmodium falciparum serine repeat antigen 3 0.032 0.0804 0.2341
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0182 0.0428 0.042
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0196 0.0196
Mycobacterium ulcerans hypothetical protein 0.0285 0.0709 0.2734
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0143 0.0322 0.0314
Loa Loa (eye worm) hypothetical protein 0.0062 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0192 0.0455 0.0454
Trypanosoma brucei antigen, putative 0.1164 0.3108 0.5048
Onchocerca volvulus 0.1274 0.3409 0.5542
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1274 0.3409 1
Brugia malayi prolyl oligopeptidase family protein 0.0302 0.0754 0.0753
Echinococcus granulosus neurocalcin 0.0182 0.0428 0.0427
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0134 0.0178
Loa Loa (eye worm) notch protein 0.0027 0.0003 0.0002
Brugia malayi Cytochrome P450 family protein 0.0036 0.0029 0.0028
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Onchocerca volvulus 0.0075 0.0134 0.0216
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0049 0.0049
Entamoeba histolytica cysteine protease, putative 0.1274 0.3409 1
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.004 0.004 0.0096
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.004 0.0053
Brugia malayi Eukaryotic aspartyl protease family protein 0.0043 0.0049 0.0048
Echinococcus multilocularis neural cadherin 0.0027 0.0003 0.0002
Trypanosoma brucei centrin-3 0.0186 0.0438 0.0701
Brugia malayi fibroinase precursor 0.032 0.0804 0.0803
Brugia malayi Muscle positioning protein 4 0.0027 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0056 0.0084 0.0084
Schistosoma mansoni caspase-7 (C14 family) 0.0242 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.3099 0.8394 0.8394
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0027 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0707 0.186 0.1854
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0041 0.0043 0.0036
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0004
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.0072 0.0072
Plasmodium vivax aspartyl proteinase, putative 0.0043 0.0049 0.0121
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0134 0.0297 0.0296
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0134 0.038
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0049 0.0048
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0186 0.0438 0.0438
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0025 0.0049
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.004 0.0053
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0134 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0099 0.0252
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.004 0.0033
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0134 0.0348
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.0319 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0707 0.186 0.5088
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.004 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.032 0.0804 0.2187
Echinococcus granulosus cathepsin b 0.3687 1 1
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0015 0.0014
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.032 0.0804 0.0804
Brugia malayi Cathepsin L-like precursor 0.0887 0.2353 0.2352
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0003
Schistosoma mansoni laminin gamma-3 chain 0.0027 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.004 0.0033
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Plasmodium falciparum serine repeat antigen 8 0.032 0.0804 0.2341
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0707 0.186 0.3016
Echinococcus granulosus beta-adrenergic receptor kinase 0.0044 0.0049 0.0048
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0041 0.0043 0.0036
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0302 0.0754 0.0754
Echinococcus granulosus prolyl endopeptidase 0.2277 0.615 0.615
Onchocerca volvulus 0.0075 0.0134 0.0216
Brugia malayi calpain 5 0.082 0.2169 0.2168
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0192 0.0455 0.0454
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0091 0.0178 0.0178
Schistosoma mansoni glycogen phosphorylase 0.0052 0.0071 0.0071
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.004 0.0033
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Entamoeba histolytica cysteine proteinase, putative 0.0707 0.186 0.5446
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0707 0.186 0.186
Giardia lamblia Proteasome subunit beta type 2 0.0091 0.0178 0.0482
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0134 0.0178
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0142 0.0319 0.0507
Giardia lamblia Cysteine protease 0.032 0.0804 0.2198
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0042
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.0045 0.0069
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0143 0.0322 0.0924
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0031 0.0015 0.002
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0948 0.2519 0.469
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0091 0.0178 0.0171
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.004 0.0096
Schistosoma mansoni cpg binding protein 0.0034 0.0022 0.0022
Trypanosoma cruzi metacaspase, putative 0.0062 0.0099 0.0092
Entamoeba histolytica protein kinase, putative 0.082 0.2169 0.6355
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Giardia lamblia Cathepsin B precursor 0.1361 0.3648 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0062 0.0099 0.0157
Onchocerca volvulus 0.0192 0.0455 0.0738
Onchocerca volvulus 0.0043 0.0049 0.0077
Echinococcus granulosus centrin 2 0.0182 0.0428 0.0427
Loa Loa (eye worm) hypothetical protein 0.3687 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0095 0.0094
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0134 0.0178
Echinococcus multilocularis tissue type plasminogen activator 0.0048 0.0062 0.0061
Echinococcus multilocularis neurocalcin 0.0182 0.0428 0.0427
Schistosoma mansoni glycogen phosphorylase 0.012 0.0257 0.0257
Plasmodium vivax serine-repeat antigen (SERA) 0.032 0.0804 0.2341
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.004 0.004 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.032 0.0804 0.2187
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.004 0.004 0.0096
Toxoplasma gondii microneme protein MIC17A 0.0031 0.0015 0.002
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.004 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0099 0.0252
Echinococcus multilocularis subfamily T1A non peptidase ue 0.004 0.004 0.0039
Echinococcus granulosus cpg binding protein 0.0036 0.0028 0.0027
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0167 0.0438
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0043 0.0049 0.0048
Echinococcus multilocularis glycogen phosphorylase 0.012 0.0257 0.0256
Brugia malayi Fli-1 protein 0.0221 0.0533 0.0532
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0041 0.0043 0.0098
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0103 0.0212 0.0211
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0167 0.0438
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1164 0.3108 0.3103
Brugia malayi hypothetical protein 0.0325 0.0818 0.0817
Brugia malayi Serine carboxypeptidase S28 family protein 0.0041 0.0043 0.0042
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0196 0.0189
Trypanosoma brucei cysteine peptidase C (CPC) 0.1361 0.3648 0.5927
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0003 0.0002
Echinococcus granulosus proteasome subunit alpha type 6 0.004 0.004 0.0039
Toxoplasma gondii hypothetical protein 0.0031 0.0015 0.002
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Schistosoma mansoni notch 0.0027 0.0003 0.0003
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.004 0.0033
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0186 0.0438 0.0437
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Brugia malayi prolyl oligopeptidase family protein 0.0637 0.1669 0.1668
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0091 0.0178 0.0502
Loa Loa (eye worm) hypothetical protein 0.0387 0.0986 0.0985
Trypanosoma brucei calmodulin, putative 0.0182 0.0428 0.0684
Plasmodium falciparum serine repeat antigen 6 0.032 0.0804 0.2341
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1274 0.3409 0.3408
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0192 0.0455 0.0454
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0818 0.0817
Schistosoma mansoni gabp alpha 0.0073 0.0129 0.0129
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0151 0.0341 0.0917
Loa Loa (eye worm) glycogen phosphorylase 0.012 0.0257 0.0256
Trypanosoma cruzi major cysteine proteinase, putative 0.032 0.0804 0.0797
Echinococcus granulosus cathepsin l cysteine peptidase 0.1274 0.3409 0.3408
Mycobacterium ulcerans zinc metalloprotease 0.0103 0.0212 0.0737
Trichomonas vaginalis calpain, putative 0.0344 0.0869 0.2366
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0041 0.0043 0.0098
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0062 0.0054
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0818 0.0817
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0151 0.0341 0.0917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0887 0.2353 0.6442
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0049 0.0049
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.032 0.0804 0.2198
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0041 0.0043 0.0036
Schistosoma mansoni cathepsin C 0.032 0.0804 0.0804
Mycobacterium tuberculosis Conserved protein 0.0285 0.0709 0.1266
Loa Loa (eye worm) RGS-3 protein 0.0044 0.0049 0.0048
Leishmania major cytochrome p450-like protein 0.0036 0.0029 0.0034
Brugia malayi hypothetical protein 0.0118 0.0253 0.0252
Trichomonas vaginalis hypothetical protein 0.0344 0.0869 0.2366
Entamoeba histolytica prolyl oligopeptidase family protein 0.0302 0.0754 0.2195
Brugia malayi programmed cell death protein 6 0.0182 0.0428 0.0427
Brugia malayi GPI-anchor transamidase 0.0035 0.0025 0.0024
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0044 0.0049 0.0048
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0049 0.0048
Trichomonas vaginalis histone deacetylase, putative 0.0087 0.0167 0.0438
Onchocerca volvulus 0.0185 0.0436 0.0707
Toxoplasma gondii cathepsin CPC1 0.032 0.0804 0.1303
Entamoeba histolytica cysteine protease, putative 0.032 0.0804 0.2341
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0029 0.0028
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.004 0.0033
Loa Loa (eye worm) hypothetical protein 0.0062 0.01 0.0099
Echinococcus multilocularis protein jagged 2 0.0027 0.0003 0.0002
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.004 0.004 0.0039
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0182 0.0428 0.1154
Schistosoma mansoni notch 0.0027 0.0003 0.0003
Brugia malayi cathepsin Z-like cysteine proteinase 0.032 0.0804 0.0803
Giardia lamblia Cathepsin B precursor 0.032 0.0804 0.2198
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0049 0.0048
Plasmodium vivax proteasome subunit beta type-7, putative 0.004 0.004 0.0096
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.004 0.004 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0134 0.0127
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1164 0.3108 0.3103
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.0862
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0049 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0134 0.0372
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.0212 0.0212
Echinococcus granulosus histone deacetylase 7 0.0098 0.0196 0.0195
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.004 0.0033
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0302 0.0754 0.0754
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1976 0.5326 1
Toxoplasma gondii cathepsin B 0.1361 0.3648 0.593
Giardia lamblia Cathepsin L precursor 0.032 0.0804 0.2198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Echinococcus granulosus fibropellin Ia 0.0027 0.0003 0.0002
Echinococcus granulosus enteropeptidase 0.0192 0.0455 0.0454
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0818 0.0817
Brugia malayi Papain family cysteine protease containing protein 0.1274 0.3409 0.3408
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0455
Leishmania major hypothetical protein, conserved 0.0185 0.0436 0.0697
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0192 0.0455 0.0454
Echinococcus multilocularis proteasome subunit alpha type 6 0.004 0.004 0.0039
Schistosoma mansoni centrin-related 0.0182 0.0428 0.0428
Plasmodium falciparum histone deacetylase 1 0.0087 0.0167 0.0469
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0332 0.0331
Giardia lamblia 20S proteasome alpha subunit 6 0.004 0.004 0.0103
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0049 0.0048
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0143 0.0322 0.0512
Plasmodium vivax aspartyl protease, putative 0.0206 0.0493 0.1426
Loa Loa (eye worm) proteasome subunit alpha type 1 0.004 0.004 0.0039
Schistosoma mansoni cathepsin F (C01 family) 0.0887 0.2353 0.2353
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.3281 0.8892 0.8892
Echinococcus granulosus notch 0.0027 0.0003 0.0002
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0041 0.0043 0.0098
Trypanosoma brucei oligopeptidase b 0.0948 0.2519 0.4089
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.004 0.004 0.0096
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0895 0.2375 0.2374
Loa Loa (eye worm) hypothetical protein 0.2279 0.6155 0.6155
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.004 0.004 0.0096
Toxoplasma gondii proteasome beta subunit 0.004 0.004 0.0061
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0095 0.0143
Trichomonas vaginalis calmodulin, putative 0.0182 0.0428 0.1154
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0134 0.0178
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1837 0.4948 0.4947
Brugia malayi EF hand family protein 0.0185 0.0436 0.0435
Trypanosoma brucei calpain, putative 0.0344 0.0869 0.1402
Brugia malayi Angiotensin-converting enzyme family protein 0.1837 0.4948 0.4947
Echinococcus granulosus histone deacetylase 6 0.0098 0.0196 0.0195
Loa Loa (eye worm) hypothetical protein 0.032 0.0804 0.0803
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Echinococcus multilocularis neuronal calcium sensor 0.0182 0.0428 0.0427
Echinococcus granulosus histone deacetylase 8 0.0042 0.0044 0.0043
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0818 0.0817
Plasmodium vivax proteasome subunit alpha type-1, putative 0.004 0.004 0.0096
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.004 0.004 0.004
Loa Loa (eye worm) calpain 0.1164 0.3108 0.3107
Loa Loa (eye worm) hypothetical protein 0.0118 0.0253 0.0252
Trypanosoma cruzi kinesin, putative 0.082 0.2169 0.2163
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0042
Trypanosoma cruzi cruzipain precursor, putative 0.0387 0.0986 0.0979
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0014
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Entamoeba histolytica cysteine protease, putative 0.032 0.0804 0.2341
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.032 0.0804 0.0803
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0044 0.0049 0.0048
Toxoplasma gondii cathepsin CPC2 0.032 0.0804 0.1303
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0637 0.1669 0.2705
Plasmodium vivax hypothetical protein, conserved 0.0302 0.0754 0.2195
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.004 0.004 0.0096
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0091 0.0178 0.0178
Schistosoma mansoni notch 0.0027 0.0003 0.0003
Onchocerca volvulus 0.0325 0.0818 0.1328
Schistosoma mansoni cathepsin S (C01 family) 0.032 0.0804 0.0804
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Echinococcus multilocularis cathepsin L cysteine protease 0.1274 0.3409 0.3408
Loa Loa (eye worm) blistered cuticle protein 3 0.0325 0.0818 0.0817
Trypanosoma brucei Metacaspase-4 0.0062 0.0099 0.0149
Leishmania major calmodulin, putative 0.0182 0.0428 0.0684
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.004 0.0033
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.004 0.0053
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0948 0.2519 0.2513
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Echinococcus granulosus glycogen phosphorylase 0.012 0.0257 0.0256
Brugia malayi EGF-like domain containing protein 0.0027 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Brugia malayi cathepsin L-like precursor 0.0887 0.2353 0.2352
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0143 0.0322 0.0314
Loa Loa (eye worm) hypothetical protein 0.0228 0.0552 0.0551
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0332 0.0332
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.004 0.0053
Echinococcus granulosus protein jagged 2 0.0027 0.0003 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.0332 0.0331
Schistosoma mansoni intermediate filament proteins 0.0026 0.0001 0.0001
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0043 0.0049 0.0113
Schistosoma mansoni cathepsin s 0.0387 0.0986 0.0986
Loa Loa (eye worm) hypothetical protein 0.0075 0.0134 0.0133
Brugia malayi proteasome subunit alpha type 1 0.004 0.004 0.0039
Leishmania major cathepsin L-like protease 0.1274 0.3409 0.5537
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0455
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.004 0.004 0.004
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1164 0.3108 0.5048
Toxoplasma gondii kringle domain-containing protein 0.0048 0.0062 0.0096
Echinococcus granulosus cathepsin L 0.032 0.0804 0.0803
Trypanosoma cruzi cysteine peptidase, putative 0.0707 0.186 0.1854
Toxoplasma gondii heat shock protein hslv, putative 0.004 0.004 0.0061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Brugia malayi aspartic protease BmAsp-1, identical 0.0043 0.0049 0.0048
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0387 0.0986 0.0985
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Plasmodium vivax plasmepsin V, putative 0.0043 0.0049 0.0121
Plasmodium vivax unspecified product 0.0387 0.0986 0.2877
Trypanosoma cruzi cysteine proteinase, putative 0.0707 0.186 0.1854
Echinococcus granulosus subfamily T1A non peptidase ue 0.004 0.004 0.0039
Trypanosoma cruzi metacaspase, putative 0.0062 0.0099 0.0092
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0455
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.004 0.0039
Entamoeba histolytica cysteine proteinase, putative 0.0707 0.186 0.5446
Brugia malayi Cytochrome P450 family protein 0.0036 0.0029 0.0028
Trypanosoma cruzi caltractin, putative 0.0182 0.0428 0.042
Schistosoma mansoni hypothetical protein 0.018 0.0422 0.0422
Trypanosoma brucei proteasome beta 3 subunit, putative 0.004 0.004 0.0053
Loa Loa (eye worm) calpain 5 0.082 0.2169 0.2168
Plasmodium vivax aspartyl proteinase, putative 0.0043 0.0049 0.0121
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0143 0.0322 0.0519
Onchocerca volvulus 0.0027 0.0003 0.0002
Loa Loa (eye worm) proteasome subunit beta type 3 0.004 0.004 0.0039
Onchocerca volvulus Huntingtin homolog 0.0118 0.0253 0.041
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1714 0.4613 0.4612
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0025 0.0062
Loa Loa (eye worm) calpain family protein 1 0.2279 0.6155 0.6155
Echinococcus granulosus Proteasome subunit alpha beta 0.004 0.004 0.0039
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0095 0.0241
Giardia lamblia 20S proteasome alpha subunit 5 0.004 0.004 0.0103
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.004 0.0096
Echinococcus multilocularis calpain 7 (C02 family) 0.1164 0.3108 0.3107
Mycobacterium tuberculosis Conserved hypothetical protein 0.0285 0.0709 0.1266
Plasmodium falciparum plasmepsin X 0.0206 0.0493 0.1426
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0078 0.0143 0.0142
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.004 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0361 0.0915 0.0914
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0087 0.0167 0.0438
Onchocerca volvulus 0.0031 0.0015 0.0023
Mycobacterium tuberculosis Conserved protein 0.0075 0.0134 0.0178
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1164 0.3108 0.3103
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.004 0.004 0.0039
Giardia lamblia Dipeptidyl-peptidase I precursor 0.032 0.0804 0.2198
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0015 0.002
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0091 0.0178 0.0177
Trichomonas vaginalis calcineurin B subunit, putative 0.0185 0.0436 0.1176
Loa Loa (eye worm) hypothetical protein 0.0075 0.0134 0.0133
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0129 0.0128
Toxoplasma gondii centrin, putative 0.0182 0.0428 0.0691
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3099 0.8394 0.8394
Toxoplasma gondii peptidase family M13 protein 0.0103 0.0212 0.0341
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0182 0.0428 0.0427
Loa Loa (eye worm) peptidase family M13 containing protein 0.0076 0.0138 0.0137
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0048 0.0062 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.032 0.0804 0.2187
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0095 0.0257
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0151 0.0341 0.0341
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0015 0.002
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.004 0.004 0.004
Onchocerca volvulus 0.0182 0.0428 0.0694
Toxoplasma gondii aspartyl protease ASP3 0.0206 0.0493 0.0797
Trichomonas vaginalis peptide N-glycanase, putative 0.0285 0.0709 0.1928
Loa Loa (eye worm) hypothetical protein 0.0118 0.0253 0.0252
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0049 0.0048
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0004
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0003 0.0002
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0134 0.0178
Echinococcus granulosus Transglutaminase 0.0285 0.0709 0.0708
Schistosoma mansoni rab 0.0182 0.0428 0.0428
Toxoplasma gondii histone deacetylase HDAC2 0.0087 0.0167 0.0268
Brugia malayi calcium-binding protein 0.0182 0.0428 0.0427
Echinococcus granulosus EF hand domain containing family member A2 0.0182 0.0428 0.0427
Brugia malayi Protein kinase domain containing protein 0.0048 0.0062 0.0061
Plasmodium falciparum plasmepsin VII 0.0043 0.0049 0.0121
Onchocerca volvulus 0.1274 0.3409 0.5542
Brugia malayi Papain family cysteine protease containing protein 0.032 0.0804 0.0803
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.004 0.004 0.0096
Plasmodium vivax histone deacetylase 2, putative 0.0098 0.0196 0.0555
Brugia malayi PAN domain containing protein 0.0031 0.0015 0.0014
Onchocerca volvulus Legumain homolog 0.0151 0.0341 0.0553
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.004 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0051 0.007 0.0069
Mycobacterium ulcerans hypothetical protein 0.0285 0.0709 0.2734
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.004 0.0096
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0027 0.0003 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0887 0.2353 0.6895
Plasmodium vivax proteasome subunit beta type-6, putative 0.004 0.004 0.0096
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Onchocerca volvulus 0.032 0.0804 0.1306
Loa Loa (eye worm) hypothetical protein 0.0192 0.0455 0.0454
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0049 0.0049
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Echinococcus granulosus calpain 0.1164 0.3108 0.3107
Brugia malayi Cathepsin L-like precursor 0.1274 0.3409 0.3408
Plasmodium falciparum proteasome subunit beta type-5 0.0249 0.0611 0.1775
Onchocerca volvulus 0.0285 0.0709 0.1152
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.004 0.0033
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0049 0.0048
Onchocerca volvulus Neurogenic locus notch homolog 0.0027 0.0003 0.0004
Leishmania major i/6 autoantigen-like protein 0.0182 0.0428 0.0684
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Schistosoma mansoni calmodulin 0.0182 0.0428 0.0428
Onchocerca volvulus Putative cubilin 0.0027 0.0003 0.0002
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.004 0.004 0.0033
Brugia malayi Cytochrome P450 family protein 0.006 0.0093 0.0092
Schistosoma mansoni ets-related 0.0221 0.0533 0.0533
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0455
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0095 0.0257
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0344 0.0869 0.1409
Echinococcus granulosus cathepsin L cysteine protease 0.0707 0.186 0.1859
Leishmania major proteasome beta-1 subunit, putative 0.004 0.004 0.0053
Onchocerca volvulus Cell death protein 3 homolog 0.0242 0.0591 0.096
Loa Loa (eye worm) hypothetical protein 0.0184 0.0433 0.0432
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0044 0.0049 0.0049
Trichomonas vaginalis set domain proteins, putative 0.0815 0.2156 0.5901
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.032 0.0804 0.2187
Trypanosoma brucei hypothetical protein, conserved 0.0182 0.0428 0.0684
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0014
Schistosoma mansoni calmodulin 0.0182 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0078 0.0143 0.0142
Schistosoma mansoni ef hand domain family member A2 0.0182 0.0428 0.0428
Echinococcus granulosus apoptotic protease activating factor 1 0.018 0.0422 0.0421
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0134 0.0348
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0887 0.2353 0.2352
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.0804 0.0804
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0049 0.0115
Loa Loa (eye worm) hypothetical protein 0.032 0.0804 0.0803
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Brugia malayi Proteasome A-type and B-type family protein 0.0249 0.0611 0.061
Trypanosoma brucei Calpain-like protein CALP1.3 0.0344 0.0869 0.1402
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.004 0.004 0.0053
Trichomonas vaginalis calcium binding protein, putative 0.0182 0.0428 0.1154
Loa Loa (eye worm) hypothetical protein 0.0103 0.0212 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1274 0.3409 0.9343
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0344 0.0869 0.0862
Loa Loa (eye worm) hypothetical protein 0.0182 0.0428 0.0427
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Trypanosoma brucei caltractin, putative 0.0186 0.0438 0.0701
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.004 0.004 0.0061
Schistosoma mansoni cathepsin D (A01 family) 0.0233 0.0567 0.0567
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.0804 0.0804
Schistosoma mansoni lamin 0.0026 0.0001 0.0001
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0344 0.0869 0.1402
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0025 0.0053
Brugia malayi carbohydrate phosphorylase 0.012 0.0257 0.0256
Mycobacterium tuberculosis Conserved hypothetical protein 0.0285 0.0709 0.1266
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0344 0.0869 0.1402
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0182 0.0428 0.1235
Schistosoma mansoni gamma-secretase subunit aph-1 0.027 0.0668 0.0668
Trypanosoma cruzi cysteine peptidase, putative 0.0387 0.0986 0.0979
Trichomonas vaginalis calcium binding protein, putative 0.0182 0.0428 0.1154
Entamoeba histolytica prolyl oligopeptidase family protein 0.0302 0.0754 0.2195
Entamoeba histolytica cysteine protease, putative 0.0707 0.186 0.5446
Loa Loa (eye worm) hypothetical protein 0.1935 0.5216 0.5216
Brugia malayi beta-lactamase family protein 0.0075 0.0134 0.0133
Brugia malayi prolyl oligopeptidase family protein 0.0302 0.0754 0.0753
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.004 0.0096
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0196 0.0189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0332 0.0332
Brugia malayi Serine protease Z688.6 precursor 0.0041 0.0043 0.0042
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0015 0.0014
Trypanosoma brucei prolyl endopeptidase 0.2277 0.615 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0044 0.0049 0.0048
Brugia malayi EGF-like domain containing protein 0.0027 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0192 0.0455 0.0455
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.004 0.004 0.0061
Brugia malayi EGF-like domain containing protein 0.0027 0.0003 0.0002
Echinococcus granulosus expressed protein 0.0851 0.2255 0.2254
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0078 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0076 0.0138 0.0137
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0003
Schistosoma mansoni slit 0.0027 0.0003 0.0003
Onchocerca volvulus 0.0192 0.0455 0.0738
Loa Loa (eye worm) hypothetical protein 0.0387 0.0986 0.0985
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0143 0.0322 0.0321
Toxoplasma gondii microneme protein, putative 0.0031 0.0015 0.002
Brugia malayi Peptidase C13 family protein 0.0151 0.0341 0.034
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0483 0.1248 0.1248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Brugia malayi proteasome subunit alpha type 6 0.004 0.004 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Leishmania major cathepsin L-like protease 0.1381 0.3702 0.6015
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0637 0.1669 0.1668
Leishmania major hypothetical protein, conserved 0.0344 0.0869 0.1402
Brugia malayi Proteasome subunit alpha type 7-1 0.004 0.004 0.0039
Brugia malayi calpain 5 0.0344 0.0869 0.0868
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0136 0.0136
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.032 0.0804 0.0804
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.004 0.0089
Entamoeba histolytica papain family cysteine protease domain containing protein 0.032 0.0804 0.2341
Loa Loa (eye worm) hypothetical protein 0.0087 0.0167 0.0166
Schistosoma mansoni mitochondrial solute carrier 0.0182 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0075 0.0134 0.0133
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.0212 0.0212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.032 0.0804 0.2187
Echinococcus granulosus cathepsin L cysteine proteinase 0.1274 0.3409 0.3408
Giardia lamblia Cathepsin L precursor 0.032 0.0804 0.2198
Trypanosoma brucei prolyl oligopeptidase, putative 0.0948 0.2519 0.4089
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0182 0.0428 0.1235
Onchocerca volvulus 0.1274 0.3409 0.5542
Echinococcus granulosus acylamino acid releasing enzyme 0.0302 0.0754 0.0753
Loa Loa (eye worm) proteasome subunit beta type 2 0.0091 0.0178 0.0177
Loa Loa (eye worm) hypothetical protein 0.0062 0.0099 0.0098
Schistosoma mansoni survival motor neuron protein 0.0056 0.0084 0.0084
Schistosoma mansoni calmodulin related calcium binding protein 0.0182 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Echinococcus granulosus protein jagged 2 0.0027 0.0003 0.0002
Trypanosoma brucei calmodulin, putative 0.0185 0.0436 0.0697
Echinococcus granulosus tissue type plasminogen activator 0.0048 0.0062 0.0061
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0044 0.0043
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3281 0.8892 0.8892
Echinococcus multilocularis expressed protein 0.0851 0.2255 0.2254
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.0332 0.0331
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0049 0.0049
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3687 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0056 0.0082 0.0081
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0099 0.0252
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0025 0.0053
Trypanosoma brucei C-8 sterol isomerase, putative 0.0361 0.0915 0.1477
Schistosoma mansoni microtubule-associated protein tau 0.1592 0.4279 0.4279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.0804 0.2187
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.032 0.0804 0.2341
Echinococcus multilocularis acylamino acid releasing enzyme 0.0302 0.0754 0.0753
Trypanosoma cruzi centrin-3 0.0186 0.0438 0.0431
Trichomonas vaginalis calmodulin, putative 0.0186 0.0438 0.1182
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.0804 0.2187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Brugia malayi Pre-SET motif family protein 0.0716 0.1886 0.1885
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Brugia malayi Trypsin family protein 0.0192 0.0455 0.0454
Brugia malayi EGF-like domain containing protein 0.0027 0.0003 0.0002
Plasmodium falciparum plasmepsin IX 0.0206 0.0493 0.1426
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.004 0.004 0.0096
Plasmodium falciparum plasmepsin IV 0.0043 0.0049 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0049 0.0115
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0075 0.0134 0.0133
Giardia lamblia Dipeptidyl-peptidase I precursor 0.032 0.0804 0.2198
Echinococcus granulosus flap endonuclease 1 0.0028 0.0007 0.0006
Brugia malayi Papain family cysteine protease containing protein 0.0707 0.186 0.1859
Onchocerca volvulus 0.0027 0.0003 0.0002
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0151 0.0341 0.0917
Brugia malayi EGF-like domain containing protein 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0325 0.0818 0.0817
Onchocerca volvulus Peroxidase homolog 0.0325 0.0818 0.1328
Schistosoma mansoni caspase-3 (C14 family) 0.0134 0.0297 0.0297
Schistosoma mansoni caspase-7 (C14 family) 0.0134 0.0297 0.0297
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0062 0.0099 0.0099
Schistosoma mansoni cercarial elastase (S01 family) 0.0192 0.0455 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Echinococcus granulosus calpain 5 0.1164 0.3108 0.3107
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.032 0.0804 0.0804
Brugia malayi hypothetical protein 0.0044 0.0049 0.0048
Leishmania major calmodulin-like protein 0.0182 0.0428 0.0684
Trichomonas vaginalis calcineurin B subunit, putative 0.0182 0.0428 0.1154
Loa Loa (eye worm) hypothetical protein 0.0042 0.0044 0.0043
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0049 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0099 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.3409 0.9343
Echinococcus multilocularis fibropellin Ia 0.0027 0.0003 0.0002
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0044 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1381 0.3702 0.6015
Trypanosoma brucei I/6 autoantigen 0.0182 0.0428 0.0684
Trypanosoma brucei calpain-like protein, putative 0.1164 0.3108 0.5048
Mycobacterium ulcerans transglutaminase family protein 0.0285 0.0709 0.2734
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0182 0.0428 0.1154
Trypanosoma brucei cysteine peptidase, putative 0.0344 0.0869 0.1402
Trypanosoma brucei metacaspase 5, putative 0.0062 0.0099 0.0149
Brugia malayi prolyl oligopeptidase family protein 0.0895 0.2375 0.2374
Leishmania major histone deacetylase, putative 0.0098 0.0196 0.0307
Echinococcus granulosus calmodulin 0.0182 0.0428 0.0427
Echinococcus granulosus caspase 3 0.0072 0.0128 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0049 0.0115
Echinococcus granulosus EF hand domain containing family member A2 0.0185 0.0436 0.0435
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.004 0.004 0.004
Mycobacterium tuberculosis Hypothetical protein 0.0285 0.0709 0.1266
Loa Loa (eye worm) hypothetical protein 0.0078 0.0143 0.0142
Trichomonas vaginalis centrin, putative 0.0182 0.0428 0.1154
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0151 0.0341 0.0917
Plasmodium falciparum plasmepsin II 0.0043 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0192 0.0455 0.0454
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0003 0.0002
Echinococcus multilocularis peroxidasin 0.0325 0.0818 0.0817
Entamoeba histolytica cysteine protease, putative 0.032 0.0804 0.2341
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0041 0.0043 0.0043
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0192 0.0455 0.0455
Trichomonas vaginalis conserved hypothetical protein 0.032 0.0804 0.2187
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0818 0.0817
Leishmania major centrin, putative 0.0182 0.0428 0.0684
Leishmania major proteasome alpha 2 subunit, putative 0.004 0.004 0.0053
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.004 0.0096
Entamoeba histolytica hypothetical protein 0.0044 0.0049 0.0123
Loa Loa (eye worm) proteasome subunit beta type 1 0.0143 0.0322 0.0321
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0003 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0049 0.0049
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0029 0.0028
Trypanosoma brucei proteasome alpha 7 subunit 0.004 0.004 0.0053
Plasmodium vivax vivapain-1 0.0707 0.186 0.5446
Loa Loa (eye worm) cathepsin B 0.1361 0.3648 0.3647
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.032 0.0804 0.2341
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0196 0.0196

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = -8.86 Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes. ChEMBL. 1992112
IC50 (binding) = 1.4 nM Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]-GR-65,630 in rat cerebral cortex. ChEMBL. 9464362
IC50 (binding) = 1.4 nM Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]-GR-65,630 in rat cerebral cortex. ChEMBL. 9464362
Log IC50 (binding) = 8.86000000000002 Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes. ChEMBL. 1992112

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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