Detailed information for compound 510760

Basic information

Technical information
  • TDR Targets ID: 510760
  • Name: (4Z)-4-[[4-(dimethylaminomethyl)anilino]methy lidene]-6-(3-methoxyanilino)isoquinoline-1,3- dione
  • MW: 442.51 | Formula: C26H26N4O3
  • H donors: 3 H acceptors: 2 LogP: 3.83 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)Nc1ccc2c(c1)/C(=C/Nc1ccc(cc1)CN(C)C)/C(=O)NC2=O
  • InChi: 1S/C26H26N4O3/c1-30(2)16-17-7-9-18(10-8-17)27-15-24-23-14-20(11-12-22(23)25(31)29-26(24)32)28-19-5-4-6-21(13-19)33-3/h4-15,27-28H,16H2,1-3H3,(H,29,31,32)/b24-15-
  • InChiKey: LIYQZXZFOLJIIM-IWIPYMOSSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (4Z)-4-[[4-(dimethylaminomethyl)anilino]methylene]-6-(3-methoxyanilino)isoquinoline-1,3-dione
  • (4Z)-4-[[[4-(dimethylaminomethyl)phenyl]amino]methylidene]-6-[(3-methoxyphenyl)amino]isoquinoline-1,3-dione
  • (4Z)-4-[[4-(dimethylaminomethyl)anilino]methylene]-6-(m-anisidino)isoquinoline-1,3-quinone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Onchocerca volvulus 0.0039 0.0047 0.0067
Leishmania major cathepsin L-like protease 0.13 0.3808 0.5374
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1077 0.3141 0.3141
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0056 0.0056
Schistosoma mansoni histone deacetylase hda2 0.0104 0.0242 0.0242
Echinococcus granulosus sodium and chloride dependent glycine 0.0183 0.0475 0.0475
Plasmodium falciparum plasmepsin VI 0.003 0.0021 0.0055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0671
Echinococcus multilocularis calpain 0.0967 0.2813 0.2813
Giardia lamblia Hypothetical protein 0.0124 0.03 0.081
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0339 0.089
Echinococcus multilocularis programmed cell death protein 0.0158 0.0403 0.0403
Echinococcus multilocularis cathepsin l cysteine peptidase 0.13 0.3808 0.3808
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0285 0.0779 0.0779
Onchocerca volvulus 0.0289 0.0794 0.112
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0317 0.0876 0.23
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0564 0.0564
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0191 0.0502
Onchocerca volvulus 0.0157 0.0399 0.0564
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.003 0.0021 0.0021
Brugia malayi Proteasome A-type and B-type family protein 0.0162 0.0412 0.0412
Trichomonas vaginalis calpain, putative 0.0285 0.0779 0.2047
Plasmodium vivax vivapain-2 0.13 0.3808 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.015 0.015
Echinococcus multilocularis EF hand domain containing family member A2 0.0157 0.0399 0.0399
Loa Loa (eye worm) calpain family protein 1 0.2577 0.7615 0.7615
Echinococcus multilocularis serotonin transporter 0.1077 0.3141 0.3141
Echinococcus granulosus caspase 2 0.0178 0.0462 0.0462
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0317 0.0876 0.0876
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0058 0.0058
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0055 0.0078
Trypanosoma brucei kinesin, putative 0.0682 0.1964 0.2772
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0078 0.0206
Echinococcus granulosus Regulator of G protein signaling 20 0.0043 0.0058 0.0058
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0043 0.0058 0.0058
Giardia lamblia Cathepsin L precursor 0.0317 0.0876 0.2369
Giardia lamblia Proteasome subunit beta type 2 0.005 0.0078 0.0212
Toxoplasma gondii troponin c, isotype gamma, putative 0.0155 0.0391 0.0552
Loa Loa (eye worm) blistered cuticle protein 3 0.0212 0.0564 0.0564
Loa Loa (eye worm) hypothetical protein 0.0074 0.015 0.015
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0179 0.0465 0.0465
Entamoeba histolytica cysteine protease, putative 0.13 0.3808 1
Trichomonas vaginalis conserved hypothetical protein 0.0317 0.0876 0.23
Plasmodium falciparum centrin-1 0.0155 0.0391 0.1028
Entamoeba histolytica cysteine proteinase, putative 0.0716 0.2065 0.5422
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0035
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0155 0.0391 0.0391
Leishmania major protein kinase, putative 0.0155 0.0391 0.0552
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0043 0.0058 0.0058
Plasmodium falciparum plasmepsin IV 0.003 0.0021 0.0055
Onchocerca volvulus Deterin homolog 0.0179 0.0465 0.0656
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0716 0.2065 0.5422
Entamoeba histolytica calpain family cysteine protease, putative 0.0285 0.0779 0.2047
Onchocerca volvulus 0.0902 0.2619 0.3697
Trypanosoma brucei protein I/6 0.0155 0.0391 0.0552
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0025 0.0087
Trypanosoma cruzi metacaspase, putative 0.0044 0.0061 0.0061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Echinococcus granulosus Mastin 0.0133 0.0327 0.0327
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0653 0.1879 0.1879
Plasmodium vivax unspecified product 0.0317 0.0876 0.23
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.01 0.0228 0.0371
Trichomonas vaginalis calcium binding protein, putative 0.0155 0.0391 0.1028
Brugia malayi histone deacetylase 11 0.0042 0.0056 0.0056
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0315 0.087 0.087
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0047 0.0077
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1263 0.3698 0.3698
Trypanosoma cruzi calmodulin, putative 0.0155 0.0391 0.0391
Mycobacterium tuberculosis Probable peptidase 0.0997 0.2903 0.4724
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0564 0.0564
Trypanosoma cruzi cysteine peptidase, putative 0.0399 0.1119 0.1119
Schistosoma mansoni caspase-3 (C14 family) 0.0117 0.0279 0.0279
Leishmania major hypothetical protein, unknown function 0.0285 0.0779 0.11
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0315 0.087 0.087
Loa Loa (eye worm) PXA domain-containing protein 0.0043 0.0058 0.0058
Giardia lamblia Cathepsin L precursor 0.0317 0.0876 0.2369
Loa Loa (eye worm) calpain D 0.0285 0.0779 0.0779
Schistosoma mansoni neuronal calcium sensor 0.0155 0.0391 0.0391
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.13 0.3808 0.3808
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0047 0.0077
Giardia lamblia Cysteine protease 0.0317 0.0876 0.2369
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0094 0.0094
Schistosoma mansoni sodium/chloride dependent transporter 0.1077 0.3141 0.3141
Echinococcus multilocularis dnaJ subfamily B 0.0455 0.1286 0.1286
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0025 0.0025
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0056 0.0056
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0025 0.0025
Giardia lamblia Hypothetical protein 0.0317 0.0876 0.2369
Trypanosoma brucei calpain-like protein, putative 0.0967 0.2813 0.3971
Plasmodium vivax vivapain-1 0.0716 0.2065 0.5422
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0061 0.0061
Echinococcus granulosus histone deacetylase 1 0.0088 0.0191 0.0191
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0021 0.0055
Toxoplasma gondii proteasome subunit beta type, putative 0.0162 0.0412 0.0582
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0345 0.1189
Giardia lamblia Sirtuin type 2 0.0032 0.0025 0.0068
Echinococcus granulosus cathepsin L cysteine protease 0.0716 0.2065 0.2065
Echinococcus multilocularis Mastin 0.0133 0.0327 0.0327
Schistosoma mansoni gabp alpha 0.007 0.0139 0.0139
Plasmodium vivax serine-repeat antigen (SERA) 0.0317 0.0876 0.23
Plasmodium falciparum serine repeat antigen 7 0.0317 0.0876 0.23
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0345 0.1189
Brugia malayi cathepsin L precursor 0.0317 0.0876 0.0876
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0317 0.0876 0.0876
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0716 0.2065 0.2914
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.01 0.0228 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0317 0.0876 0.23
Plasmodium falciparum histone deacetylase 1 0.0088 0.0191 0.0502
Giardia lamblia Cysteine protease 0.0317 0.0876 0.2369
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.3971
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0345 0.0345
Trichomonas vaginalis centrin, putative 0.0155 0.0391 0.1028
Trypanosoma brucei Calpain-like protein 2 0.0285 0.0779 0.11
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Plasmodium vivax hypothetical protein, conserved 0.0315 0.087 0.2285
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0047 0.0163
Toxoplasma gondii microneme protein, putative 0.003 0.002 0.0028
Trichomonas vaginalis calmodulin-2, putative 0.0155 0.0391 0.1028
Trypanosoma cruzi I/6 autoantigen, putative 0.0155 0.0391 0.0391
Brugia malayi cathepsin F-like cysteine proteinase 0.0317 0.0876 0.0876
Echinococcus multilocularis calumenin 0.0157 0.0399 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0317 0.0876 0.23
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trypanosoma brucei hypothetical protein, conserved 0.0155 0.0391 0.0552
Echinococcus granulosus proteasome prosome macropain 0.0162 0.0412 0.0412
Loa Loa (eye worm) ctsf protein 0.13 0.3808 0.3808
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0047 0.0163
Brugia malayi Peptidase family M13 containing protein 0.01 0.0228 0.0228
Plasmodium vivax proteasome subunit beta type-2, putative 0.005 0.0078 0.0206
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0035 0.0035
Onchocerca volvulus 0.0133 0.0327 0.0461
Entamoeba histolytica cysteine proteinase, putative 0.0716 0.2065 0.5422
Trichomonas vaginalis conserved hypothetical protein 0.0317 0.0876 0.23
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2731 0.8077 0.8077
Trypanosoma cruzi conserved protein 0.0285 0.0779 0.0779
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1209 0.3538 0.3538
Trypanosoma brucei histone deacetylase 4 0.0098 0.0224 0.0315
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Plasmodium vivax vivapain-2 0.13 0.3808 1
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0056 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0357 0.0357
Onchocerca volvulus 0.0183 0.0475 0.0671
Onchocerca volvulus 0.003 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0399 0.1119 0.1119
Echinococcus multilocularis enteropeptidase 0.0133 0.0327 0.0327
Brugia malayi EF hand family protein 0.0157 0.0399 0.0399
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0564 0.0564
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0133 0.0327 0.0327
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0285 0.0779 0.2047
Echinococcus granulosus histone deacetylase 6 0.0104 0.0242 0.0242
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0162 0.0412 0.0582
Brugia malayi Cathepsin L-like precursor 0.0902 0.2619 0.2619
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0013 0.0019
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0012 0.0017
Entamoeba histolytica calcium binding family protein 0.0155 0.0391 0.1028
Entamoeba histolytica glycogen phosphorylase, putative 0.0115 0.0274 0.0721
Onchocerca volvulus Prolyl endopeptidase homolog 0.2399 0.7086 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0049 0.0129
Loa Loa (eye worm) hypothetical protein 0.0105 0.0244 0.0244
Onchocerca volvulus 0.0793 0.2295 0.3239
Onchocerca volvulus 0.0101 0.0231 0.0326
Trypanosoma brucei Calpain-like protein 1.2 0.0285 0.0779 0.11
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0191 0.0191
Toxoplasma gondii aspartyl protease 0.003 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Echinococcus granulosus biogenic amine 5HT receptor 0.0553 0.1579 0.1579
Trypanosoma brucei prolyl endopeptidase 0.2399 0.7086 1
Echinococcus granulosus importin subunit beta 1 0.0028 0.0013 0.0013
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0653 0.1879 0.1879
Giardia lamblia Cathepsin B precursor 0.1263 0.3698 1
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0139 0.0139
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0357 0.0357
Echinococcus multilocularis calcium uptake protein 1 0.0157 0.0399 0.0399
Plasmodium falciparum cysteine proteinase falcipain 3 0.13 0.3808 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.023 0.023
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0003 0.0003
Echinococcus granulosus cathepsin b 0.3376 1 1
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0078 0.0078
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0162 0.0412 0.0412
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.023 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Trichomonas vaginalis peptide N-glycanase, putative 0.0289 0.0794 0.2084
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0653 0.1879 0.1879
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0317 0.0876 0.2369
Trichomonas vaginalis calmodulin, putative 0.0155 0.0391 0.1028
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0317 0.0876 0.0876
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Toxoplasma gondii EFHC1, putative 0.0155 0.0391 0.0552
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0297 0.0817 0.0817
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0049 0.0069
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Entamoeba histolytica histone deacetylase, putative 0.0088 0.0191 0.0502
Plasmodium vivax amine transporter, putative 0.0183 0.0475 0.1248
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0058 0.0058
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0653 0.1879 0.1879
Toxoplasma gondii PAN domain-containing protein 0.003 0.002 0.0028
Loa Loa (eye worm) calpain 5 0.0682 0.1964 0.1964
Leishmania major calmodulin-like protein 0.0155 0.0391 0.0552
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0779 0.2252 0.2252
Plasmodium vivax centrin-1, putative 0.0155 0.0391 0.1028
Trypanosoma cruzi centrin-3 0.0158 0.0403 0.0403
Plasmodium falciparum amino acid transporter, putative 0.0183 0.0475 0.1248
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0285 0.0779 0.2047
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0025 0.0036
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0285 0.0779 0.2047
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0339 0.089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0779 0.0779
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Loa Loa (eye worm) fli-1 protein 0.0213 0.0565 0.0565
Echinococcus multilocularis regulator of G protein signaling 0.0043 0.0058 0.0058
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0317 0.0876 0.0876
Onchocerca volvulus 0.003 0.0021 0.003
Echinococcus granulosus EF hand domain containing family member A2 0.0155 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Leishmania major calcineurin B subunit, putative 0.0155 0.0391 0.0552
Loa Loa (eye worm) hypothetical protein 0.0168 0.0432 0.0432
Echinococcus multilocularis centrin 2 0.0155 0.0391 0.0391
Toxoplasma gondii microneme protein MIC17A 0.003 0.002 0.0028
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0056 0.0079
Echinococcus granulosus cathepsin l1 0.13 0.3808 0.3808
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0317 0.0876 0.2369
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0035 0.0093
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0779 0.0779
Entamoeba histolytica protein kinase, putative 0.0682 0.1964 0.5159
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0077 0.016 0.042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0716 0.2065 0.2914
Echinococcus granulosus expressed protein 0.0831 0.2408 0.2408
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Brugia malayi Peptidase C13 family protein 0.0152 0.0383 0.0383
Brugia malayi hypothetical protein 0.0043 0.0058 0.0058
Schistosoma mansoni chromatin regulatory protein sir2 0.0137 0.0339 0.0339
Toxoplasma gondii hypothetical protein 0.0183 0.0475 0.0671
Brugia malayi cathepsin Z-like cysteine proteinase 0.0317 0.0876 0.0876
Trypanosoma cruzi major cysteine proteinase, putative 0.0317 0.0876 0.0876
Loa Loa (eye worm) programmed cell death protein 6 0.0157 0.0399 0.0399
Toxoplasma gondii hypothetical protein 0.003 0.002 0.0028
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Leishmania major centrin, putative 0.0155 0.0391 0.0552
Toxoplasma gondii centrin 0.0155 0.0391 0.0552
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0317 0.0876 0.23
Plasmodium falciparum plasmepsin X 0.0109 0.0256 0.0672
Brugia malayi prolyl oligopeptidase family protein 0.2399 0.7086 0.7086
Brugia malayi Cathepsin L-like precursor 0.0902 0.2619 0.2619
Schistosoma mansoni rab 0.0155 0.0391 0.0391
Leishmania major cysteine peptidase A (CPA) 0.13 0.3808 0.5374
Echinococcus granulosus cathepsin L 0.0716 0.2065 0.2065
Brugia malayi Calmodulin-like protein 0.0155 0.0391 0.0391
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3376 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0317 0.0876 0.23
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0061 0.0061
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0058 0.0058
Echinococcus multilocularis calbindin 32 0.0157 0.0399 0.0399
Schistosoma mansoni memapsin-2 (A01 family) 0.0491 0.1394 0.1394
Echinococcus granulosus caspase 8 0.0044 0.0061 0.0061
Trypanosoma brucei metacaspase MCA2 0.0044 0.0061 0.0087
Echinococcus granulosus flap endonuclease 1 0.0027 0.0012 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0055 0.0055
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0035 0.0035
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0162 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trichomonas vaginalis calmodulin, putative 0.0155 0.0391 0.1028
Brugia malayi Papain family cysteine protease containing protein 0.13 0.3808 0.3808
Loa Loa (eye worm) hypothetical protein 0.0043 0.0058 0.0058
Echinococcus multilocularis expressed protein 0.0831 0.2408 0.2408
Loa Loa (eye worm) hypothetical protein 0.0317 0.0876 0.0876
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Onchocerca volvulus 0.13 0.3808 0.5374
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0967 0.2813 0.2813
Echinococcus granulosus EF hand domain containing family member A2 0.0157 0.0399 0.0399
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0383 0.1006
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0055 0.0145
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Schistosoma mansoni biogenic amine (5HT) receptor 0.0553 0.1579 0.1579
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0056 0.0056
Leishmania major cathepsin L-like protease 0.13 0.3808 0.5374
Trypanosoma brucei proteasome beta 6 subunit 0.0077 0.016 0.0226
Onchocerca volvulus Cathepsin L homolog 0.0317 0.0876 0.1236
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Loa Loa (eye worm) hypothetical protein 0.0133 0.0327 0.0327
Schistosoma mansoni calpain-7 (C02 family) 0.097 0.2823 0.2823
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0035 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0224 0.0224
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0261 0.0708 0.0708
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Mycobacterium ulcerans beta-lactamase 0.0039 0.0047 0.0163
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1006 0.2932 0.2932
Brugia malayi hypothetical protein 0.0133 0.0327 0.0327
Brugia malayi PXA domain containing protein 0.0043 0.0058 0.0058
Toxoplasma gondii preprocathepsin c precursor, putative 0.0317 0.0876 0.1236
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0025 0.0066
Leishmania major histone deacetylase, putative 0.0088 0.0191 0.027
Trypanosoma cruzi centrin, putative 0.0158 0.0403 0.0403
Leishmania major metacaspase, putative 0.0044 0.0061 0.0087
Toxoplasma gondii exonuclease III APE 0.004 0.0049 0.0069
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0025 0.0066
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0066
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0317 0.0876 0.2369
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0364 0.1015 0.1015
Trypanosoma cruzi major cysteine proteinase, putative 0.0422 0.1188 0.1188
Plasmodium vivax serine-repeat antigen (SERA) 0.0317 0.0876 0.23
Schistosoma mansoni survival motor neuron protein 0.0101 0.0231 0.0231
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0025 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0564 0.0564
Loa Loa (eye worm) hypothetical protein 0.0902 0.2619 0.2619
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.0311 0.0311
Trypanosoma brucei Calpain-like protein 1.1 0.0285 0.0779 0.11
Plasmodium vivax histone deacetylase 1, putative 0.0088 0.0191 0.0502
Onchocerca volvulus 0.0039 0.0047 0.0067
Trichomonas vaginalis calcium binding protein, putative 0.0155 0.0391 0.1028
Brugia malayi programmed cell death protein 6 0.0155 0.0391 0.0391
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0967 0.2813 0.2813
Mycobacterium tuberculosis Conserved protein 0.0039 0.0047 0.0077
Loa Loa (eye worm) glycogen phosphorylase 0.0115 0.0274 0.0274
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3376 1 1
Onchocerca volvulus 0.0212 0.0564 0.0796
Onchocerca volvulus 0.0212 0.0564 0.0796
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0061
Brugia malayi NAD-dependent deacetylase SIRT1 0.0137 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Onchocerca volvulus 0.0055 0.0094 0.0133
Echinococcus multilocularis histone deacetylase 0.0098 0.0224 0.0224
Schistosoma mansoni ef hand domain family member A2 0.0155 0.0391 0.0391
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Loa Loa (eye worm) hypothetical protein 0.0424 0.1193 0.1193
Echinococcus granulosus cathepsin L 0.0317 0.0876 0.0876
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0025 0.0025
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0077 0.016 0.016
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0179 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0075 0.0155 0.0155
Echinococcus multilocularis sodium and chloride dependent glycine 0.0183 0.0475 0.0475
Echinococcus granulosus calpain 7 C02 family 0.0967 0.2813 0.2813
Trichomonas vaginalis centrin, putative 0.0155 0.0391 0.1028
Onchocerca volvulus Chorion peroxidase homolog 0.0212 0.0564 0.0796
Loa Loa (eye worm) histone deacetylase 3 0.0088 0.0191 0.0191
Plasmodium vivax hypothetical protein, conserved 0.0157 0.0399 0.1049
Plasmodium falciparum serine repeat antigen 5 0.0317 0.0876 0.23
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0055 0.0149
Trypanosoma cruzi cysteine peptidase, putative 0.1405 0.412 0.412
Loa Loa (eye worm) hypothetical protein 0.0134 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0399 0.1119 0.1119
Echinococcus granulosus calpain 0.0967 0.2813 0.2813
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0058 0.0151
Onchocerca volvulus Cathepsin F homolog 0.13 0.3808 0.5374
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0043 0.0058 0.0058
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0155 0.0391 0.0391
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trypanosoma cruzi metacaspase, putative 0.0044 0.0061 0.0061
Echinococcus multilocularis glycoprotein Antigen 5 0.0133 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0133 0.0327 0.0327
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0317 0.0876 0.0876
Echinococcus granulosus EF HAND 1 calcium binding site 0.0155 0.0391 0.0391
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0047 0.0069 0.0181
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0317 0.0876 0.23
Schistosoma mansoni reticulocalbin 0.0157 0.0399 0.0399
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0025 0.0041
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Loa Loa (eye worm) histone deacetylase 1 0.0088 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0075 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0043 0.0058 0.0058
Schistosoma mansoni cpg binding protein 0.0034 0.0031 0.0031
Entamoeba histolytica calcium-binding protein, putative 0.0155 0.0391 0.1028
Loa Loa (eye worm) hypothetical protein 0.0133 0.0327 0.0327
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0049 0.017
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0564 0.0564
Entamoeba histolytica calmodulin, putative 0.0155 0.0391 0.1028
Giardia lamblia Cathepsin B precursor 0.1263 0.3698 1
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0317 0.0876 0.23
Echinococcus multilocularis Glycosyl transferase, family 35 0.0115 0.0274 0.0274
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0285 0.0779 0.2047
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0025 0.0025
Onchocerca volvulus 0.13 0.3808 0.5374
Loa Loa (eye worm) solute carrier family 6 member 4 0.1077 0.3141 0.3141
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0061 0.0061
Echinococcus multilocularis calmodulin 0.0155 0.0391 0.0391
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0012 0.0032
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.005 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.1077 0.3141 0.3141
Brugia malayi Histone deacetylase family protein 0.0098 0.0224 0.0224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0058 0.0058
Plasmodium vivax aspartyl protease, putative 0.0109 0.0256 0.0672
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0025 0.0036
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0779 0.0779
Echinococcus multilocularis calmodulin 0.0155 0.0391 0.0391
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0133 0.0327 0.0327
Leishmania major hypothetical protein, conserved 0.0039 0.0047 0.0067
Onchocerca volvulus 0.0155 0.0391 0.0552
Toxoplasma gondii calmodulin CAM1 0.0157 0.0399 0.0564
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0055
Brugia malayi Cathepsin L-like precursor 0.0399 0.1119 0.1119
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Echinococcus granulosus programmed cell death protein 0.0158 0.0403 0.0403
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0779 0.0779
Toxoplasma gondii cathepsin CPL 0.13 0.3808 0.5374
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0162 0.0412 0.142
Loa Loa (eye worm) serotonin transporter b 0.1077 0.3141 0.3141
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1263 0.3698 0.3698
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0191 0.0502
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1263 0.3698 0.9711
Brugia malayi Pepsin A precursor 0.003 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0168 0.0432 0.0609
Toxoplasma gondii microneme protein MIC17C 0.003 0.002 0.0028
Leishmania major hypothetical protein, conserved 0.0157 0.0399 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0317 0.0876 0.23
Plasmodium falciparum plasmepsin VII 0.003 0.0021 0.0055
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0013 0.0013
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0183 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Loa Loa (eye worm) transcriptional regulator 0.0124 0.03 0.03
Echinococcus granulosus enteropeptidase 0.0133 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0183 0.0475 0.0475
Onchocerca volvulus Cell death protein 3 homolog 0.0178 0.0462 0.0652
Onchocerca volvulus 0.13 0.3808 0.5374
Brugia malayi Peroxidasin 0.0212 0.0564 0.0564
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.2084 0.6146 1
Leishmania major cathepsin L-like protease 0.1405 0.412 0.5815
Echinococcus multilocularis transmembrane protease serine 3 0.0133 0.0327 0.0327
Onchocerca volvulus Dual oxidase homolog 0.0212 0.0564 0.0796
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Echinococcus multilocularis Regulator of G protein signaling 20 0.0043 0.0058 0.0058
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0058 0.0058
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0224 0.0224
Leishmania major oligopeptidase b 0.0997 0.2903 0.4097
Trypanosoma brucei calpain, putative 0.0285 0.0779 0.11
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0183 0.0475 0.0475
Trypanosoma brucei centrin-3 0.0158 0.0403 0.0568
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0317 0.0876 0.23
Onchocerca volvulus 0.0133 0.0327 0.0461
Schistosoma mansoni sodium/chloride dependent transporter 0.0183 0.0475 0.0475
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0012 0.0012
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0914 0.2657 0.2657
Echinococcus multilocularis calpain A 0.2734 0.8085 0.8085
Schistosoma mansoni hemoglobinase (C13 family) 0.0152 0.0383 0.0383
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.13 0.3808 1
Giardia lamblia Hypothetical protein 0.0289 0.0794 0.2146
Loa Loa (eye worm) sirtuin 4 0.0032 0.0025 0.0025
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0047 0.0077
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0035 0.005
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.002 0.002
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.3971
Trichomonas vaginalis calmodulin, putative 0.0155 0.0391 0.1028
Giardia lamblia Cathepsin B precursor 0.1263 0.3698 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0049 0.0049
Echinococcus granulosus inhibitor of apoptosis protein 0.0179 0.0465 0.0465
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0155 0.0391 0.0391
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.0311 0.0311
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0055 0.0145
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0285 0.0779 0.0779
Schistosoma mansoni neuronal calcium sensor 0.0155 0.0391 0.0391
Echinococcus granulosus dnaJ subfamily B 0.0455 0.1286 0.1286
Schistosoma mansoni hypothetical protein 0.0179 0.0465 0.0465
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0061 0.0161
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Trichomonas vaginalis calcium binding protein, putative 0.0158 0.0403 0.1057
Schistosoma mansoni hypothetical protein 0.0297 0.0817 0.0817
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Brugia malayi Protein kinase domain containing protein 0.0047 0.0069 0.0069
Plasmodium falciparum plasmepsin VIII, putative 0.003 0.0021 0.0055
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0155 0.0391 0.1028
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0025 0.0025
Brugia malayi fibroinase precursor 0.0317 0.0876 0.0876
Loa Loa (eye worm) calpain family protein 1 0.1895 0.5581 0.5581
Schistosoma mansoni hypothetical protein 0.0133 0.0327 0.0327
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Echinococcus granulosus histone deacetylase 3 0.0088 0.0191 0.0191
Loa Loa (eye worm) EF hand family protein 0.0155 0.0391 0.0391
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0056 0.0079
Echinococcus granulosus cathepsin l cysteine peptidase 0.13 0.3808 0.3808
Echinococcus multilocularis histone deacetylase 3 0.0088 0.0191 0.0191
Trichomonas vaginalis calcium binding protein, putative 0.0155 0.0391 0.1028
Echinococcus granulosus histone deacetylase 7 0.0098 0.0224 0.0224
Trichomonas vaginalis hypothetical protein 0.0285 0.0779 0.2047
Giardia lamblia Cathepsin L-like protease 0.0317 0.0876 0.2369
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0317 0.0876 0.23
Echinococcus multilocularis EF hand domain containing family member A2 0.0155 0.0391 0.0391
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2399 0.7086 0.7086
Leishmania major cathepsin L-like protease 0.1405 0.412 0.5815
Trypanosoma brucei cysteine peptidase, putative 0.0285 0.0779 0.11
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0035 0.0096
Brugia malayi Kringle domain containing protein 0.0047 0.0069 0.0069
Echinococcus multilocularis cysteine protease 0.13 0.3808 0.3808
Loa Loa (eye worm) hypothetical protein 0.1077 0.3141 0.3141
Brugia malayi Thioredoxin family protein 0.0289 0.0794 0.0794
Trypanosoma brucei calpain-like protein, putative 0.0967 0.2813 0.3971
Schistosoma mansoni caspase-7 (C14 family) 0.0178 0.0462 0.0462
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0047 0.0047
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0061 0.0087
Echinococcus multilocularis cathepsin b 0.3376 1 1
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.005 0.0078 0.0206
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.002 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0357 0.0357
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.008 0.008
Toxoplasma gondii PAN domain-containing protein 0.003 0.002 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0061 0.0161
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0021 0.0055
Echinococcus granulosus glycoprotein Antigen 5 0.0133 0.0327 0.0327
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0055 0.0055
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0357 0.0357
Onchocerca volvulus 0.13 0.3808 0.5374
Loa Loa (eye worm) proteasome subunit beta type 2 0.005 0.0078 0.0078
Entamoeba histolytica cysteine proteinase, putative 0.0902 0.2619 0.6879
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0997 0.2903 1
Echinococcus granulosus transmembrane protease serine 3 0.0133 0.0327 0.0327
Leishmania major hypothetical protein, conserved 0.0047 0.0069 0.0098
Schistosoma mansoni sodium-dependent amino acid transporter 0.0183 0.0475 0.0475
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0117 0.0279 0.0279
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0186 0.0485 0.0485
Onchocerca volvulus 0.0183 0.0475 0.0671
Giardia lamblia Cathepsin B precursor 0.0317 0.0876 0.2369
Loa Loa (eye worm) hypothetical protein 0.0495 0.1405 0.1405
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0183 0.0475 1
Schistosoma mansoni endothelin-converting enzyme-related 0.0024 0.0003 0.0003
Trypanosoma cruzi kinesin, putative 0.0682 0.1964 0.1964
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0066
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0025 0.0066
Echinococcus granulosus neuronal calcium sensor 0.0155 0.0391 0.0391
Echinococcus granulosus chromatin regulatory protein sir2 0.0124 0.03 0.03
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0967 0.2813 0.2813
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Echinococcus multilocularis hypothetical protein 0.0967 0.2813 0.2813
Schistosoma mansoni calpain-2 (C02 family) 0.0285 0.0779 0.0779
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0058 0.0058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0967 0.2813 0.2813
Brugia malayi Importin beta-1 subunit 0.0028 0.0013 0.0013
Loa Loa (eye worm) calmodulin-like protein 0.0155 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0155 0.0391 0.0391
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0317 0.0876 0.0876
Leishmania major cytochrome p450-like protein 0.0035 0.0035 0.005
Schistosoma mansoni gamma-secretase subunit aph-1 0.0261 0.0708 0.0708
Trypanosoma brucei antigen, putative 0.0967 0.2813 0.3971
Leishmania major i/6 autoantigen-like protein 0.0155 0.0391 0.0552
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0242 0.0242
Trypanosoma brucei calmodulin, putative 0.0157 0.0399 0.0564
Brugia malayi Papain family cysteine protease containing protein 0.0716 0.2065 0.2065
Schistosoma mansoni calmodulin related calcium binding protein 0.0155 0.0391 0.0391
Plasmodium falciparum cysteine repeat modular protein 1 0.0047 0.0069 0.0181
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0061 0.0161
Leishmania major calmodulin, putative 0.0155 0.0391 0.0552
Brugia malayi Trypsin family protein 0.0133 0.0327 0.0327
Loa Loa (eye worm) histone deacetylase 7A 0.0098 0.0224 0.0224
Brugia malayi prolyl oligopeptidase family protein 0.0315 0.087 0.087
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Plasmodium falciparum plasmepsin III 0.003 0.0021 0.0055
Toxoplasma gondii proteasome subunit beta type 2, putative 0.005 0.0078 0.0111
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0564 0.0564
Echinococcus granulosus Glycosyl transferase family 35 0.0115 0.0274 0.0274
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0317 0.0876 0.0876
Schistosoma mansoni hypothetical protein 0.0289 0.0794 0.0794
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0155 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0043 0.0058 0.0058
Echinococcus multilocularis geminin 0.0174 0.0449 0.0449
Brugia malayi regulator of G-protein signaling rgs-7 0.0043 0.0058 0.0058
Onchocerca volvulus 0.1077 0.3141 0.4433
Brugia malayi A-kinase anchor protein 10, precursor 0.0043 0.0058 0.0058
Schistosoma mansoni Nep2 peptidase (M13 family) 0.005 0.008 0.008
Schistosoma mansoni glycogen phosphorylase 0.0115 0.0274 0.0274
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Plasmodium falciparum calpain 0.0285 0.0779 0.2047
Echinococcus granulosus calpain A 0.2734 0.8085 0.8085
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0317 0.0876 0.0876
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0035 0.0035
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0137 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.1895 0.5581 0.5581
Plasmodium falciparum serine repeat antigen 9 0.0317 0.0876 0.23
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0012 0.0032
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0047 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0779 0.0779
Mycobacterium ulcerans putative transglutaminase-like protein 0.0289 0.0794 0.2734
Mycobacterium leprae probable zinc metalloprotease 0.01 0.0228 0.0785
Loa Loa (eye worm) hypothetical protein 0.0049 0.0078 0.0078
Echinococcus multilocularis glycogen phosphorylase 0.0115 0.0274 0.0274
Plasmodium vivax aspartyl protease, putative 0.003 0.0021 0.0055
Schistosoma mansoni hypothetical protein 0.0047 0.0069 0.0069
Brugia malayi cathepsin Z-like cysteine proteinase 0.0317 0.0876 0.0876
Onchocerca volvulus 0.003 0.002 0.0028
Schistosoma mansoni Mername-AA248 (C02 family) 0.0967 0.2813 0.2813
Giardia lamblia Cathepsin B precursor 0.0317 0.0876 0.2369
Loa Loa (eye worm) hypothetical protein 0.01 0.0228 0.0228
Echinococcus multilocularis cathepsin b 0.3376 1 1
Trichomonas vaginalis calcineurin B subunit, putative 0.0155 0.0391 0.1028
Loa Loa (eye worm) hypothetical protein 0.2399 0.7086 0.7086
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0013 0.0019
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0012 0.0032
Brugia malayi prolyl oligopeptidase family protein 0.0315 0.087 0.087
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3376 1 1
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0997 0.2903 0.2903
Loa Loa (eye worm) hypothetical protein 0.0075 0.0155 0.0155
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0078 0.0206
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.0056
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0049 0.0129
Loa Loa (eye worm) hypothetical protein 0.0183 0.0475 0.0475
Onchocerca volvulus Cathepsin L homolog 0.13 0.3808 0.5374
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0155 0.0391 0.1028
Loa Loa (eye worm) hypothetical protein 0.0075 0.0155 0.0155
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0317 0.0876 0.23
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0345 0.1189
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0317 0.0876 0.23
Echinococcus multilocularis cysteine protease 0.13 0.3808 0.3808
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0716 0.2065 0.2065
Echinococcus granulosus tissue type plasminogen activator 0.0047 0.0069 0.0069
Schistosoma mansoni neuronal calcium sensor 0.0155 0.0391 0.0391
Plasmodium vivax plasmepsin V, putative 0.003 0.0021 0.0055
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.03 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0317 0.0876 0.23
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0058 0.0058
Brugia malayi hypothetical protein 0.0183 0.0475 0.0475
Mycobacterium ulcerans hypothetical protein 0.0289 0.0794 0.2734
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0124 0.03 0.0423
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0317 0.0876 0.23
Giardia lamblia Hypothetical protein 0.0317 0.0876 0.2369
Toxoplasma gondii hypothetical protein 0.0285 0.0779 0.11
Leishmania major calmodulin-like protein 0.0155 0.0391 0.0552
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0055 0.0055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.3971
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0875 0.254 0.254
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0025 0.0066
Schistosoma mansoni mitochondrial solute carrier 0.0155 0.0391 0.0391
Onchocerca volvulus 0.0179 0.0465 0.0656
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.2813
Schistosoma mansoni hypothetical protein 0.0133 0.0327 0.0327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Schistosoma mansoni cathepsin D (A01 family) 0.0122 0.0295 0.0295
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0035 0.0093
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0056 0.0056
Brugia malayi Fli-1 protein 0.0213 0.0565 0.0565
Brugia malayi Pre-SET motif family protein 0.01 0.023 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0317 0.0876 0.23
Leishmania major calpain protease-like protein 0.0285 0.0779 0.11
Brugia malayi cathepsin F-like cysteine proteinase 0.0399 0.1119 0.1119
Trypanosoma cruzi cysteine peptidase, putative 0.13 0.3808 0.3808
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0162 0.0412 0.1115
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0124 0.03 0.03
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0285 0.0779 0.0779
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0047 0.0077
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0139 0.0345 0.0345
Schistosoma mansoni hypothetical protein 0.0134 0.0331 0.0331
Trypanosoma cruzi oligopeptidase b 0.0997 0.2903 0.2903
Schistosoma mansoni peroxidasin 0.0212 0.0564 0.0564
Brugia malayi histone deacetylase 1 (HD1) 0.0088 0.0191 0.0191
Brugia malayi beta-lactamase 0.0039 0.0047 0.0047
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0317 0.0876 0.0876
Trypanosoma brucei cysteine peptidase C (CPC) 0.1263 0.3698 0.5219
Entamoeba histolytica hypothetical protein 0.0043 0.0058 0.0151
Mycobacterium tuberculosis Long conserved protein 0.0289 0.0794 0.1291
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0155 0.0391 0.0391
Schistosoma mansoni hypothetical protein 0.0117 0.0278 0.0278
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0183 0.0475 0.0475
Schistosoma mansoni cathepsin F (C01 family) 0.13 0.3808 0.3808
Echinococcus granulosus beta-adrenergic receptor kinase 0.0043 0.0058 0.0058
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0025 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0145
Echinococcus granulosus peroxidasin 0.0212 0.0564 0.0564
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0317 0.0876 0.23
Trypanosoma cruzi 20S proteasome subunit 0.005 0.0078 0.0078
Entamoeba histolytica grainin, putative 0.0157 0.0399 0.1049
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0133 0.0327 0.0327
Onchocerca volvulus 0.003 0.002 0.0028
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0049 0.0049
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0079 0.0208
Onchocerca volvulus Peroxidasin homolog 0.0212 0.0564 0.0796
Plasmodium vivax aspartyl protease, putative 0.0109 0.0256 0.0672
Plasmodium falciparum cysteine proteinase falcipain 2a 0.13 0.3808 1
Loa Loa (eye worm) histone deacetylase 0.0098 0.0224 0.0224
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0049 0.0129
Echinococcus granulosus geminin 0.0174 0.0449 0.0449
Toxoplasma gondii aspartyl protease ASP1 0.003 0.0021 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Echinococcus granulosus prolyl endopeptidase 0.2399 0.7086 0.7086
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0317 0.0876 0.23
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0117 0.0279 0.0279
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0653 0.1879 0.2651
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0058 0.0058
Loa Loa (eye worm) trypsin family protein 0.0133 0.0327 0.0327
Giardia lamblia Cysteine protease 0.0317 0.0876 0.2369
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0155 0.0391 0.0391
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0025 0.0025
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.0058 0.0058
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0047 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Brugia malayi hypothetical protein 0.003 0.0021 0.0021
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0133 0.0327 0.0327
Trypanosoma brucei Aph-1 protein, putative 0.0102 0.0233 0.0329
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Brugia malayi hypothetical protein 0.0134 0.0331 0.0331
Toxoplasma gondii hypothetical protein 0.0315 0.087 0.1228
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0047 0.0047
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.03 0.03
Trypanosoma brucei centrin, putative 0.0155 0.0391 0.0552
Trichomonas vaginalis conserved hypothetical protein 0.0285 0.0779 0.2047
Echinococcus multilocularis caspase 0.0117 0.0279 0.0279
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0035 0.0035
Leishmania major phospholipase c-like protein 0.0155 0.0391 0.0552
Leishmania major proteasome beta 5 subunit, putative 0.0162 0.0412 0.0582
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0013 0.0019
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0997 0.2903 0.4097
Trypanosoma cruzi I/6 autoantigen, putative 0.0155 0.0391 0.0391
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0012 0.0012
Onchocerca volvulus 0.13 0.3808 0.5374
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0317 0.0876 0.2369
Onchocerca volvulus 0.161 0.4732 0.6679
Trypanosoma brucei caltractin, putative 0.0158 0.0403 0.0568
Trypanosoma brucei proteasome subunit beta type-2, putative 0.005 0.0078 0.0111
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0671
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Echinococcus granulosus apoptotic protease activating factor 1 0.0134 0.0331 0.0331
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0077 0.016 0.0226
Echinococcus granulosus histone deacetylase 6 0.0098 0.0224 0.0224
Entamoeba histolytica cysteine proteinase, putative 0.13 0.3808 1
Giardia lamblia Transglutaminase/protease, putative 0.0289 0.0794 0.2146
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0997 0.2903 1
Trypanosoma brucei histone deacetylase 1 0.0088 0.0191 0.027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0047 0.0069 0.0069
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Trypanosoma brucei mitochondrial calcium uptake 1 0.0155 0.0391 0.0552
Entamoeba histolytica cysteine protease, putative 0.0317 0.0876 0.23
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0077 0.016 0.042
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0224 0.0224
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0047 0.0125
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Giardia lamblia Histone deacetylase 0.0088 0.0191 0.0517
Onchocerca volvulus 0.0133 0.0327 0.0461
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0317 0.0876 0.0876
Leishmania major proteasome beta 2 subunit, putative 0.005 0.0078 0.0111
Onchocerca volvulus 0.0183 0.0475 0.0671
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0049 0.008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.023 0.023
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0162 0.0412 0.1083
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Plasmodium falciparum proteasome subunit beta type-5 0.0162 0.0412 0.1083
Brugia malayi calpain 7 0.0967 0.2813 0.2813
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0049 0.0049
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1263 0.3698 0.5219
Brugia malayi calpain family protein 1 0.2577 0.7615 0.7615
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0058 0.0058
Trypanosoma cruzi metacaspase, putative 0.0044 0.0061 0.0061
Plasmodium vivax proteasome subunit beta type-1, putative 0.0077 0.016 0.042
Loa Loa (eye worm) aspartic protease BmAsp-1 0.003 0.0021 0.0021
Toxoplasma gondii cathepsin CPC2 0.0317 0.0876 0.1236
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.087 0.2285
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0967 0.2813 0.2813
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0475
Trypanosoma cruzi oligopeptidase b 0.0997 0.2903 0.2903
Trypanosoma cruzi cysteine peptidase, putative 0.1405 0.412 0.412
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0049 0.0133
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.005 0.008 0.008
Loa Loa (eye worm) proteasome subunit beta type 1 0.0077 0.016 0.016
Echinococcus granulosus caspase 0.0117 0.0279 0.0279
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.2813
Trypanosoma cruzi cruzipain precursor, putative 0.1405 0.412 0.412
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0564 0.0564
Loa Loa (eye worm) RGS-3 protein 0.0043 0.0058 0.0058
Echinococcus multilocularis histone deacetylase 7 0.0098 0.0224 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0058 0.0058
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0055 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Trypanosoma brucei C-8 sterol isomerase, putative 0.0364 0.1015 0.1433
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Brugia malayi Trypsin family protein 0.0133 0.0327 0.0327
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0035 0.005
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0077 0.016 0.016
Toxoplasma gondii PAN domain-containing protein 0.003 0.002 0.0028
Onchocerca volvulus 0.0047 0.0069 0.0098
Brugia malayi Pre-SET motif family protein 0.0696 0.2008 0.2008
Schistosoma mansoni cpg binding protein 0.0034 0.0031 0.0031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Mycobacterium ulcerans hypothetical protein 0.0289 0.0794 0.2734
Schistosoma mansoni neuronal calcium sensor 0.0155 0.0391 0.0391
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.2813
Onchocerca volvulus Glycogen phosphorylase homolog 0.0115 0.0274 0.0387
Schistosoma mansoni hypothetical protein 0.0285 0.0779 0.0779
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1077 0.3141 0.3141
Mycobacterium ulcerans proteasome PrcB 0.0162 0.0412 0.142
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0155 0.0391 0.1028
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.005 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0056 0.0098 0.0098
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2731 0.8077 0.8077
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Trypanosoma brucei metacaspase MCA3 0.0044 0.0061 0.0087
Brugia malayi Cytochrome P450 family protein 0.0035 0.0035 0.0035
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0399 0.1119 0.1119
Onchocerca volvulus 0.01 0.023 0.0325
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0317 0.0876 0.23
Mycobacterium tuberculosis Hypothetical protein 0.0289 0.0794 0.1291
Toxoplasma gondii subtilisin SUB12 0.003 0.002 0.0028
Entamoeba histolytica prolyl oligopeptidase family protein 0.0315 0.087 0.2285
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0133 0.0327 0.0327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Toxoplasma gondii histone deacetylase HDAC3 0.0088 0.0191 0.027
Brugia malayi EF hand family protein 0.0155 0.0391 0.0391
Echinococcus granulosus endothelin converting enzyme 1 0.01 0.0228 0.0228
Trichomonas vaginalis set domain proteins, putative 0.0793 0.2294 0.6025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Plasmodium falciparum plasmepsin I 0.003 0.0021 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0058 0.0151
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0475
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0058 0.0058
Trypanosoma brucei histone deacetylase 2 0.0042 0.0056 0.0079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0357 0.0357
Brugia malayi Cathepsin L-like cysteine proteinase 0.0902 0.2619 0.2619
Echinococcus granulosus survival motor neuron protein 1 0.0495 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0062 0.0116 0.0116
Onchocerca volvulus 0.003 0.002 0.0028
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.005 0.0079 0.0129
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3376 1 1
Plasmodium falciparum peptidase, putative 0.0315 0.087 0.2285
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Echinococcus multilocularis cathepsin l cysteine peptidase 0.13 0.3808 0.3808
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trichomonas vaginalis calpain, putative 0.0285 0.0779 0.2047
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0162 0.0412 0.0412
Schistosoma mansoni hypothetical protein 0.0174 0.0449 0.0449
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0315 0.087 0.2285
Schistosoma mansoni calpain-7 (C02 family) 0.097 0.2823 0.2823
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0155 0.0391 0.0552
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0061 0.0087
Brugia malayi Ets-domain containing protein 0.007 0.0139 0.0139
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0061 0.0061
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0055 0.0145
Trichomonas vaginalis calcium binding proteins, putative 0.0155 0.0391 0.1028
Loa Loa (eye worm) hypothetical protein 0.13 0.3808 0.3808
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0383 0.1006
Trypanosoma cruzi cysteine peptidase, putative 0.0716 0.2065 0.2065
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0285 0.0779 0.11
Toxoplasma gondii histone deacetylase HDAC2 0.0088 0.0191 0.027
Echinococcus multilocularis apoptotic protease activating factor 1 0.0134 0.0331 0.0331
Onchocerca volvulus 0.0134 0.0331 0.0467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0317 0.0876 0.23
Giardia lamblia Cathepsin B precursor 0.0317 0.0876 0.2369
Loa Loa (eye worm) peptidase family M13 containing protein 0.0074 0.015 0.015
Giardia lamblia Cathepsin L-like protease 0.0317 0.0876 0.2369
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Entamoeba histolytica cysteine protease, putative 0.0317 0.0876 0.23
Trypanosoma brucei centrin, putative 0.0155 0.0391 0.0552
Loa Loa (eye worm) beta-lactamase 0.0039 0.0047 0.0047
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Echinococcus granulosus snurportin 1 0.0297 0.0817 0.0817
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0183 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0137 0.0339 0.0339
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0315 0.087 0.087
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.03 0.0787
Brugia malayi Cathepsin L-like precursor 0.13 0.3808 0.3808
Trypanosoma cruzi cysteine protease, putative 0.0716 0.2065 0.2065
Brugia malayi beta-lactamase family protein 0.0039 0.0047 0.0047
Echinococcus granulosus calcium uptake protein 1 0.0157 0.0399 0.0399
Echinococcus granulosus serotonin transporter 0.1077 0.3141 0.3141
Echinococcus granulosus histone deacetylase 8 0.0042 0.0056 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Echinococcus granulosus calpain A 0.0967 0.2813 0.2813
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0077 0.016 0.016
Schistosoma mansoni cathepsin s 0.0399 0.1119 0.1119
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0155 0.0391 0.0391
Brugia malayi hypothetical protein 0.023 0.0615 0.0615
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0058 0.0058
Brugia malayi RNA, U transporter 1 0.0079 0.0167 0.0167
Schistosoma mansoni reticulocalbin 0.0155 0.0391 0.0391
Leishmania major silent information regulator 2, putative 0.0124 0.03 0.0423
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0183 0.0475 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0058 0.0151
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0152 0.0383 0.0383
Echinococcus granulosus centrin 2 0.0155 0.0391 0.0391
Entamoeba histolytica grainin 2 0.0158 0.0403 0.1057
Trypanosoma brucei calpain, putative 0.0285 0.0779 0.11
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0025 0.0025
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.023 0.023
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Trypanosoma brucei I/6 autoantigen 0.0155 0.0391 0.0552
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.003 0.0021 0.003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0475
Brugia malayi proteasome subunit beta type 2 0.005 0.0078 0.0078
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0047 0.0077
Trypanosoma cruzi caltractin, putative 0.0155 0.0391 0.0391
Echinococcus granulosus calbindin 32 0.0157 0.0399 0.0399
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0047 0.0125
Onchocerca volvulus Peroxidase homolog 0.0212 0.0564 0.0796
Schistosoma mansoni glycogen phosphorylase 0.005 0.0079 0.0079
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0317 0.0876 0.23
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0183 0.0475 0.0475
Plasmodium vivax unspecified product 0.0716 0.2065 0.5422
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Loa Loa (eye worm) hypothetical protein 0.023 0.0615 0.0615
Loa Loa (eye worm) TK/ROR protein kinase 0.0047 0.0069 0.0069
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0139 0.0139
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0025 0.0025
Brugia malayi prolyl oligopeptidase family protein 0.0914 0.2657 0.2657
Brugia malayi Cytochrome P450 family protein 0.0035 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0043 0.0058 0.0151
Brugia malayi Blistered cuticle protein 3 0.0212 0.0564 0.0564
Loa Loa (eye worm) animal heme peroxidase 0.0212 0.0564 0.0564
Entamoeba histolytica cysteine proteinase, putative 0.13 0.3808 1
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0997 0.2903 0.4724
Entamoeba histolytica cysteine proteinase, putative 0.0716 0.2065 0.5422
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0179 0.0465 0.0465
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0061 0.0161
Onchocerca volvulus 0.0133 0.0327 0.0461
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0155 0.0391 0.1028
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0155 0.0391 0.1028
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0399 0.1119 0.1119
Toxoplasma gondii cathepsin CPC1 0.0317 0.0876 0.1236
Loa Loa (eye worm) fibroinase 0.13 0.3808 0.3808
Echinococcus multilocularis caspase 2 0.0178 0.0462 0.0462
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0025 0.0066
Onchocerca volvulus Peroxidasin homolog 0.0212 0.0564 0.0796
Brugia malayi calcium-binding protein 0.0155 0.0391 0.0391
Trichomonas vaginalis calcineurin B subunit, putative 0.0157 0.0399 0.1049
Loa Loa (eye worm) hypothetical protein 0.0902 0.2619 0.2619
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Mycobacterium ulcerans zinc metalloprotease 0.01 0.0228 0.0785
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0058 0.0058
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0914 0.2657 0.3749
Echinococcus granulosus acylamino acid releasing enzyme 0.0315 0.087 0.087
Loa Loa (eye worm) hypothetical protein 0.0155 0.0391 0.0391
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.002 0.0028
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0096 0.0217 0.0217
Toxoplasma gondii centrin, putative 0.0155 0.0391 0.0552
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0047 0.0125
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Loa Loa (eye worm) hypothetical protein 0.0399 0.1119 0.1119
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0183 0.0475 0.0475
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0779 0.0779
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0285 0.0779 0.0779
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0357 0.0357
Brugia malayi transcriptional regulator, Sir2 family protein 0.0124 0.03 0.03
Toxoplasma gondii prolyl endopeptidase 0.2399 0.7086 1
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0058 0.0151
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0055 0.0145
Onchocerca volvulus 0.003 0.002 0.0028
Trypanosoma cruzi cruzipain precursor, putative 0.0399 0.1119 0.1119
Entamoeba histolytica prolyl oligopeptidase family protein 0.0315 0.087 0.2285
Echinococcus granulosus Dipeptidyl peptidase 9 0.0653 0.1879 0.1879
Schistosoma mansoni peroxidasin 0.0212 0.0564 0.0564
Schistosoma mansoni hypothetical protein 0.0155 0.0391 0.0391
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0285 0.0779 0.11
Plasmodium falciparum serine repeat antigen 1 0.0317 0.0876 0.23
Brugia malayi Trypsin family protein 0.0133 0.0327 0.0327
Entamoeba histolytica calmodulin, putative 0.0155 0.0391 0.1028
Plasmodium falciparum histone deacetylase, putative 0.0098 0.0224 0.0587
Loa Loa (eye worm) hypothetical protein 0.161 0.4732 0.4732
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Trichomonas vaginalis calpain, putative 0.0285 0.0779 0.2047
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0012 0.0032
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0137 0.0339 0.0916
Leishmania major cathepsin L-like protease 0.1405 0.412 0.5815
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0035 0.0093
Entamoeba histolytica calpain large subunit domain III containing protein 0.0682 0.1964 0.5159
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0055 0.0055
Onchocerca volvulus 0.0155 0.0391 0.0552
Trypanosoma cruzi cysteine peptidase, putative 0.1405 0.412 0.412
Loa Loa (eye worm) hypothetical protein 0.0183 0.0475 0.0475
Trypanosoma cruzi kinesin, putative 0.0682 0.1964 0.1964
Loa Loa (eye worm) hypothetical protein 0.0183 0.0475 0.0475
Brugia malayi cathepsin L-like precursor 0.0902 0.2619 0.2619
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0043 0.0058 0.0058
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0025 0.0066
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0475
Plasmodium falciparum histone deacetylase 2 0.0098 0.0224 0.0587
Echinococcus multilocularis endothelin converting enzyme 1 0.01 0.0228 0.0228
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0545 0.1555 0.2195
Echinococcus multilocularis inhibitor of apoptosis protein 0.0179 0.0465 0.0465
Trypanosoma cruzi cysteine proteinase, putative 0.0716 0.2065 0.2065
Echinococcus multilocularis acylamino acid releasing enzyme 0.0315 0.087 0.087
Loa Loa (eye worm) hypothetical protein 0.0043 0.0058 0.0058
Echinococcus granulosus tumor protein p63 0.0376 0.1052 0.1052
Echinococcus multilocularis cpg binding protein 0.0034 0.0031 0.0031
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0779 0.2252 0.2252
Loa Loa (eye worm) hypothetical protein 0.0553 0.1579 0.1579
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0058 0.0058
Brugia malayi hypothetical protein 0.0495 0.1405 0.1405
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0122 0.0172
Echinococcus multilocularis caspase 3 0.0073 0.0148 0.0148
Giardia lamblia Proteasome subunit beta type 1 0.0077 0.016 0.0432
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0026 0.0026
Onchocerca volvulus Legumain homolog 0.0152 0.0383 0.0541
Brugia malayi histone deacetylase 3 (HD3) 0.0088 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0553 0.1579 0.1579
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0055 0.0055
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0066
Echinococcus granulosus sodium and chloride dependent glycine 0.0183 0.0475 0.0475
Schistosoma mansoni cathepsin F (C01 family) 0.13 0.3808 0.3808
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0035 0.0035
Trypanosoma brucei Metacaspase-4 0.0044 0.0061 0.0087
Treponema pallidum sodium- and chloride- dependent transporter 0.1077 0.3141 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Plasmodium falciparum serine repeat antigen 3 0.0317 0.0876 0.23
Onchocerca volvulus 0.0032 0.0026 0.0036
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2399 0.7086 1
Echinococcus multilocularis microtubule associated protein 2 0.1572 0.462 0.462
Onchocerca volvulus 0.003 0.002 0.0028
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Schistosoma mansoni neprilysin-2 (M13 family) 0.005 0.008 0.008
Brugia malayi Eukaryotic aspartyl protease family protein 0.003 0.0021 0.0021
Onchocerca volvulus 0.003 0.002 0.0028
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0475
Brugia malayi beta-lactamase family protein 0.0039 0.0047 0.0047
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.023 0.023
Brugia malayi Animal haem peroxidase family protein 0.0212 0.0564 0.0564
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.3971
Loa Loa (eye worm) hypothetical protein 0.0183 0.0475 0.0475
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0035 0.0093
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0902 0.2619 0.2619
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0155 0.0391 0.0391
Leishmania major hypothetical protein, conserved 0.0155 0.0391 0.0552
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0139 0.0345 0.0345
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0055 0.0094 0.0094
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trypanosoma brucei metacaspase 0.0044 0.0061 0.0087
Trichomonas vaginalis calmodulin, putative 0.0155 0.0391 0.1028
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0183 0.0475 0.0671
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni cpg binding protein 0.0032 0.0026 0.0026
Schistosoma mansoni hemoglobinase (C13 family) 0.0152 0.0383 0.0383
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.0679 0.1104
Echinococcus multilocularis caspase 8 0.0044 0.0061 0.0061
Trypanosoma brucei oligopeptidase b 0.0997 0.2903 0.4097
Plasmodium vivax histone deacetylase 2, putative 0.0098 0.0224 0.0587
Schistosoma mansoni hypothetical protein 0.0455 0.1286 0.1286
Toxoplasma gondii peptidase family M13 protein 0.01 0.0228 0.0322
Trichomonas vaginalis glycogen phosphorylase, putative 0.0115 0.0274 0.0721
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Mycobacterium leprae Conserved hypothetical protein 0.0289 0.0794 0.2734
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Echinococcus multilocularis histone deacetylase 1 0.0088 0.0191 0.0191
Trypanosoma cruzi calmodulin, putative 0.0155 0.0391 0.0391
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2577 0.7615 0.7615
Brugia malayi Histone deacetylase 1 0.0088 0.0191 0.0191
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0157 0.0399 0.0399
Trichomonas vaginalis calmodulin, putative 0.0155 0.0391 0.1028
Trypanosoma cruzi histone deacetylase, putative 0.0098 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0133 0.0327 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0058 0.0151
Brugia malayi Angiotensin-converting enzyme family protein 0.1209 0.3538 0.3538
Plasmodium falciparum metacaspase-like protein 0.0044 0.0061 0.0161
Loa Loa (eye worm) peptidase C13 family protein 0.0152 0.0383 0.0383
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0124 0.03 0.0787
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0012 0.0017
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0317 0.0876 0.0876
Mycobacterium tuberculosis Conserved protein 0.0039 0.0047 0.0077
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0024 0.0003 0.0003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Toxoplasma gondii histone deacetylase HDAC1 0.0098 0.0224 0.0315
Echinococcus granulosus gamma secretase subunit aph 1 0.0261 0.0708 0.0708
Schistosoma mansoni calmodulin 0.0155 0.0391 0.0391
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0155 0.0391 0.0391
Leishmania major centrin, putative 0.0155 0.0391 0.0552
Trypanosoma cruzi Aph-1 protein, putative 0.0102 0.0233 0.0233
Brugia malayi calpain D 0.0285 0.0779 0.0779
Onchocerca volvulus 0.0039 0.0047 0.0067
Echinococcus multilocularis chromatin regulatory protein sir2 0.0124 0.03 0.03
Mycobacterium ulcerans hypothetical protein 0.0133 0.0327 0.1125
Loa Loa (eye worm) cysteine protease 0.13 0.3808 0.3808
Mycobacterium ulcerans transglutaminase family protein 0.0289 0.0794 0.2734
Leishmania major cathepsin L-like protease 0.13 0.3808 0.5374
Echinococcus multilocularis calpain family protein 1, d 0.1895 0.5581 0.5581
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Giardia lamblia Cathepsin L precursor 0.0317 0.0876 0.2369
Echinococcus multilocularis sodium and chloride dependent glycine 0.0183 0.0475 0.0475
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0317 0.0876 0.23
Giardia lamblia Encystation-specific protease 0.0317 0.0876 0.2369
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Echinococcus multilocularis proteasome (prosome, macropain) 0.0162 0.0412 0.0412
Echinococcus multilocularis Transglutaminase 0.0289 0.0794 0.0794
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0317 0.0876 0.0876
Trypanosoma brucei prolyl oligopeptidase, putative 0.0997 0.2903 0.4097
Plasmodium falciparum serine repeat antigen 2 0.0317 0.0876 0.23
Echinococcus granulosus histone deacetylase 0.0098 0.0224 0.0224
Toxoplasma gondii hypothetical protein 0.003 0.002 0.0028
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0025 0.0036
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0058 0.0058
Echinococcus multilocularis histone deacetylase 6 0.0098 0.0224 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0061 0.0161
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0055 0.0055
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0317 0.0876 0.23
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0047 0.0077
Trypanosoma cruzi prolyl endopeptidase 0.2399 0.7086 0.7086
Trypanosoma brucei calpain-like protein, putative 0.0967 0.2813 0.3971
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0049 0.0049
Plasmodium falciparum proteasome subunit beta type-2, putative 0.005 0.0078 0.0206
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0035 0.0122
Plasmodium falciparum plasmepsin IX 0.0109 0.0256 0.0672
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.003 0.0021 0.0055
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0155 0.0391 0.0552
Loa Loa (eye worm) hypothetical protein 0.0183 0.0475 0.0475
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0139 0.0345 0.0487
Toxoplasma gondii hypothetical protein 0.0183 0.0475 0.0671
Brugia malayi hypothetical protein 0.003 0.0021 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0357 0.0357
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0058 0.0058
Echinococcus multilocularis calpain 7 (C02 family) 0.0967 0.2813 0.2813
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2731 0.8077 0.8077
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0967 0.2813 0.2813
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0049 0.0069
Trichomonas vaginalis myosin light chain 1, putative 0.0155 0.0391 0.1028
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0025 0.0036
Entamoeba histolytica cysteine protease, putative 0.0317 0.0876 0.23
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0055 0.0145
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0653 0.1879 0.2651
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0049 0.0129
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Echinococcus granulosus cathepsin l1 0.0902 0.2619 0.2619
Trypanosoma brucei calpain-like protein, putative 0.0967 0.2813 0.3971
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0025 0.0025
Echinococcus granulosus neurocalcin 0.0155 0.0391 0.0391
Echinococcus granulosus microtubule associated protein 2 0.1572 0.462 0.462
Trypanosoma brucei histone deacetylase 3 0.0098 0.0224 0.0315
Schistosoma mansoni microtubule-associated protein tau 0.1572 0.462 0.462
Schistosoma mansoni cathepsin D (A01 family) 0.0122 0.0295 0.0295
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0162 0.0412 0.0671
Entamoeba histolytica cysteine protease, putative 0.0317 0.0876 0.23
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0012 0.0017
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Onchocerca volvulus 0.13 0.3808 0.5374
Giardia lamblia Alanyl dipeptidyl peptidase 0.0315 0.087 0.2353
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0139 0.0139
Giardia lamblia Cathepsin L precursor 0.0317 0.0876 0.2369
Plasmodium falciparum serine repeat antigen 8 0.0317 0.0876 0.23
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0364 0.1015 0.1015
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0047 0.0125
Plasmodium vivax calpain, putative 0.0967 0.2813 0.7388
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0035 0.0093
Trypanosoma brucei calmodulin, putative 0.0155 0.0391 0.0552
Brugia malayi proteasome subunit beta type 1 0.0077 0.016 0.016
Plasmodium falciparum transporter, putative 0.0183 0.0475 0.1248
Toxoplasma gondii aldehyde dehydrogenase 0.0139 0.0345 0.0487
Echinococcus multilocularis calpain 5 0.0967 0.2813 0.2813
Echinococcus multilocularis cathepsin L cysteine protease 0.13 0.3808 0.3808
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0357 0.0357
Leishmania major C-8 sterol isomerase-like protein 0.0364 0.1015 0.1433
Brugia malayi Flap endonuclease-1 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0317 0.0876 0.0876
Mycobacterium tuberculosis Conserved protein 0.0289 0.0794 0.1291
Brugia malayi PXA domain containing protein 0.0043 0.0058 0.0058
Onchocerca volvulus 0.0317 0.0876 0.1236
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Plasmodium falciparum plasmepsin II 0.003 0.0021 0.0055
Giardia lamblia Glycogen phosphorylase 0.0115 0.0274 0.0742
Leishmania major kinesin, putative 0.0682 0.1964 0.2772
Plasmodium vivax importin-beta 2, putative 0.0028 0.0013 0.0035
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0077 0.016 0.016
Brugia malayi aspartic protease BmAsp-2, identical 0.003 0.0021 0.0021
Echinococcus granulosus glycogen phosphorylase 0.0115 0.0274 0.0274
Schistosoma mansoni calpain C (C02 family) 0.0967 0.2813 0.2813
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Brugia malayi Cathepsin L-like precursor 0.13 0.3808 0.3808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0902 0.2619 0.6879
Loa Loa (eye worm) hypothetical protein 0.3376 1 1
Schistosoma mansoni calmodulin 0.0155 0.0391 0.0391
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0056 0.0056
Brugia malayi Cell death protein 3 precursor 0.0178 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.0075 0.0155 0.0155
Trypanosoma cruzi metacaspase, putative 0.0044 0.0061 0.0061
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0191 0.0502
Entamoeba histolytica glycogenphosphorylase, putative 0.005 0.0079 0.0208
Plasmodium vivax hypothetical protein, conserved 0.0183 0.0475 0.1248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0902 0.2619 0.6879
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0191 0.0502
Loa Loa (eye worm) hypothetical protein 0.2292 0.6766 0.6766
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0049 0.0129
Plasmodium vivax vivapain-3 0.0716 0.2065 0.5422
Mycobacterium ulcerans hypothetical protein 0.0039 0.0047 0.0163
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Trichomonas vaginalis glycogen phosphorylase, putative 0.0115 0.0274 0.0721
Onchocerca volvulus 0.0049 0.0078 0.011
Brugia malayi Histone deacetylase family protein 0.0098 0.0224 0.0224
Echinococcus multilocularis glycogen phosphorylase 0.0115 0.0274 0.0274
Schistosoma mansoni hypothetical protein 0.0026 0.0008 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0357 0.0357
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0055 0.0145
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0049 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0339 0.089
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.023 0.0325
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0055
Onchocerca volvulus 0.0133 0.0327 0.0461
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.03 0.03
Entamoeba histolytica cysteine protease, putative 0.0317 0.0876 0.23
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0145
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0997 0.2903 0.4097
Giardia lamblia Cathepsin L precursor 0.0317 0.0876 0.2369
Leishmania major cathepsin L-like protease 0.13 0.3808 0.5374
Brugia malayi peptidase family M13 containing protein 0.0024 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0013
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0066
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0047 0.0067
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.11
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0315 0.087 0.087
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0155 0.0391 0.1028
Brugia malayi Trypsin-like protease protein 5 0.0133 0.0327 0.0327
Loa Loa (eye worm) peptidase family M13 containing protein 0.0074 0.015 0.015
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0047 0.0163
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0026 0.0008 0.0008
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.0057 0.008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0061 0.0087
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Schistosoma mansoni sodium/chloride dependent transporter 0.0183 0.0475 0.0475
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0183 0.0475 0.0475
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Schistosoma mansoni cercarial elastase (S01 family) 0.0133 0.0327 0.0327
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0383 0.1006
Plasmodium falciparum metacaspase 1 0.0044 0.0061 0.0161
Onchocerca volvulus 0.0042 0.0055 0.0078
Schistosoma mansoni cathepsin B (C01 family) 0.0317 0.0876 0.0876
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0317 0.0876 0.23
Onchocerca volvulus 0.0133 0.0327 0.0461
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0383 0.1006
Giardia lamblia Cathepsin B precursor 0.0317 0.0876 0.2369
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0162 0.0412 0.0412
Brugia malayi GPI-anchor transamidase 0.0035 0.0035 0.0035
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0696 0.2008 0.2008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0317 0.0876 0.23
Onchocerca volvulus 0.13 0.3808 0.5374
Echinococcus granulosus calumenin 0.0157 0.0399 0.0399
Echinococcus multilocularis serotonin receptor 0.0553 0.1579 0.1579
Brugia malayi carbohydrate phosphorylase 0.0115 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0088 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0074 0.015 0.015
Entamoeba histolytica cysteine protease, putative 0.0317 0.0876 0.23
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0179 0.0465 0.0465
Entamoeba histolytica cysteine proteinase 1, putative 0.0716 0.2065 0.5422
Onchocerca volvulus 0.003 0.002 0.0028
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0155 0.0391 0.0391
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.002 0.002
Mycobacterium leprae Conserved hypothetical protein 0.0289 0.0794 0.2734
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0157 0.0399 0.0399
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.023 0.023
Entamoeba histolytica hypothetical protein 0.0043 0.0058 0.0151
Echinococcus multilocularis cathepsin L 0.0317 0.0876 0.0876
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0058 0.0058
Plasmodium vivax plasmepsin IV, putative 0.003 0.0021 0.0055
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0104 0.0104
Mycobacterium tuberculosis Conserved protein 0.0039 0.0047 0.0077
Trichomonas vaginalis calmodulin, putative 0.0155 0.0391 0.1028
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0061 0.0161
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0914 0.2657 0.2657
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0285 0.0779 0.0779
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Trypanosoma brucei hypothetical protein 0.0285 0.0779 0.11
Entamoeba histolytica prolyl oligopeptidase family protein 0.0315 0.087 0.2285
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0285 0.0779 0.11
Schistosoma mansoni cathepsin C 0.0317 0.0876 0.0876
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Trichomonas vaginalis calmodulin, putative 0.0157 0.0399 0.1049
Loa Loa (eye worm) hypothetical protein 0.0133 0.0327 0.0327
Loa Loa (eye worm) prolyl oligopeptidase 0.0914 0.2657 0.2657
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0231 0.0231
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0317 0.0876 0.0876
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0716 0.2065 0.5422
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Toxoplasma gondii PAN domain-containing protein 0.003 0.002 0.0028
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.01 0.0228 0.0228
Echinococcus multilocularis neuronal calcium sensor 0.0155 0.0391 0.0391
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0047 0.0125
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0049 1
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0179 0.0465 0.0465
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0315 0.087 0.1228
Toxoplasma gondii aspartyl protease ASP3 0.0109 0.0256 0.0361
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0364 0.1015 0.1015
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0043 0.0058 0.0151
Brugia malayi Cathepsin L-like precursor 0.13 0.3808 0.3808
Leishmania major calpain family cysteine protease-like protein 0.0285 0.0779 0.11
Toxoplasma gondii calcium-dependent protein kinase 0.0157 0.0399 0.0564
Schistosoma mansoni histone deacetylase 4 5 0.0098 0.0224 0.0224
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3376 1 1
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0317 0.0876 0.23
Loa Loa (eye worm) hypothetical protein 0.006 0.0109 0.0109
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0779 0.2252 0.2252
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0383 0.1006
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0047 0.0047
Brugia malayi Cytochrome P450 family protein 0.0058 0.0104 0.0104
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0345 0.0345
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0967 0.2813 0.3971
Toxoplasma gondii cathepsin B 0.1263 0.3698 0.5219
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0179 0.0465 0.0465
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0191 0.0502
Schistosoma mansoni centrin-related 0.0155 0.0391 0.0391
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0779 0.0779
Brugia malayi Cathepsin L-like precursor 0.13 0.3808 0.3808
Plasmodium falciparum flap endonuclease 1 0.0027 0.0012 0.0032
Loa Loa (eye worm) aspartyl protease 6 0.003 0.0021 0.0021
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0383 0.1006
Brugia malayi cathepsin L-like cysteine proteinase 0.0317 0.0876 0.0876
Loa Loa (eye worm) zinc metallopeptidase 4 0.0024 0.0003 0.0003
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0317 0.0876 0.23
Leishmania major programmed cell death 6 protein-like protein 0.0155 0.0391 0.0552
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0317 0.0876 0.23
Schistosoma mansoni ets-related 0.0213 0.0565 0.0565
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.03 0.0787
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0069 0.0069
Trypanosoma brucei histone deacetylase, putative 0.0098 0.0224 0.0315
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0133 0.0327 0.0327
Brugia malayi hypothetical protein 0.0168 0.0432 0.0432
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0043 0.0058 0.0058
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0191 0.0502
Plasmodium falciparum importin beta, putative 0.0028 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Mycobacterium ulcerans lipase LipD 0.0039 0.0047 0.0163
Plasmodium falciparum plasmepsin V 0.003 0.0021 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.13 0.3808 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0191 0.0502
Loa Loa (eye worm) hypothetical protein 0.0178 0.0462 0.0462
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0043 0.0058 0.0058
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.005 0.0079 0.0273
Loa Loa (eye worm) hypothetical protein 0.0317 0.0876 0.0876
Plasmodium falciparum cysteine proteinase falcipain 1 0.0716 0.2065 0.5422
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Onchocerca volvulus Peroxidase homolog 0.0212 0.0564 0.0796
Loa Loa (eye worm) hypothetical protein 0.2577 0.7615 0.7615
Giardia lamblia Cathepsin B precursor 0.0317 0.0876 0.2369
Giardia lamblia Cathepsin L precursor 0.0317 0.0876 0.2369
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0035 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0716 0.2065 0.5422
Trypanosoma brucei Calpain-like protein CALP1.3 0.0285 0.0779 0.11
Brugia malayi hypothetical protein 0.0043 0.0058 0.0058
Brugia malayi calpain 5 0.0285 0.0779 0.0779
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Leishmania major histone deacetylase, putative 0.0088 0.0191 0.027
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0339 0.089
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0143 0.0143
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0035 0.0035
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0003 0.0003
Echinococcus granulosus cathepsin b 0.3376 1 1
Leishmania major hypothetical protein, conserved 0.0285 0.0779 0.11
Brugia malayi aspartic protease BmAsp-1, identical 0.003 0.0021 0.0021
Entamoeba histolytica hypothetical protein, conserved 0.0315 0.087 0.2285
Loa Loa (eye worm) calpain 0.0967 0.2813 0.2813
Plasmodium falciparum serine repeat antigen 4 0.0317 0.0876 0.23
Brugia malayi Papain family cysteine protease containing protein 0.0317 0.0876 0.0876
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Trypanosoma cruzi hypothetical protein, conserved 0.0315 0.087 0.087
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0317 0.0876 0.23
Schistosoma mansoni ap endonuclease 0.004 0.0049 0.0049
Trypanosoma cruzi cysteine proteinase, putative 0.0716 0.2065 0.2065
Leishmania major centrin, putative,caltractin, putative 0.0155 0.0391 0.0552
Brugia malayi Papain family cysteine protease containing protein 0.0716 0.2065 0.2065
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.03 0.03
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0317 0.0876 0.23
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0315 0.087 0.2285
Mycobacterium tuberculosis Conserved hypothetical protein 0.0289 0.0794 0.1291
Echinococcus multilocularis programmed cell death protein 0.0158 0.0403 0.0403
Schistosoma mansoni cathepsin S (C01 family) 0.0317 0.0876 0.0876
Schistosoma mansoni cathepsin F (C01 family) 0.0902 0.2619 0.2619
Brugia malayi Cathepsin L-like precursor 0.13 0.3808 0.3808
Giardia lamblia Serine peptidase, putative 0.0042 0.0055 0.0149
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0055 0.0055
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0285 0.0779 0.11
Loa Loa (eye worm) hypothetical protein 0.0075 0.0155 0.0155
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Loa Loa (eye worm) hypothetical protein 0.01 0.023 0.023
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0079 0.0208
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0285 0.0779 0.2047
Brugia malayi prolyl oligopeptidase family protein 0.0653 0.1879 0.1879
Toxoplasma gondii kringle domain-containing protein 0.0047 0.0069 0.0098
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0035 0.005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0058 0.0058
Entamoeba histolytica glycogen phosphorylase, putative 0.0115 0.0274 0.0721
Loa Loa (eye worm) hypothetical protein 0.0133 0.0327 0.0327
Onchocerca volvulus 0.003 0.0021 0.003
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0049 0.0049
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0124 0.03 0.03
Echinococcus granulosus caspase 3 0.0073 0.0148 0.0148
Toxoplasma gondii microneme protein MIC4 0.003 0.002 0.0028
Toxoplasma gondii EF hand domain-containing protein 0.0155 0.0391 0.0552
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0317 0.0876 0.23
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0047 0.0047
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0383 0.1006
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Leishmania major histone deacetylase, putative 0.0098 0.0224 0.0315
Giardia lamblia Cysteine protease 0.0317 0.0876 0.2369
Onchocerca volvulus 0.0212 0.0564 0.0796
Echinococcus multilocularis snurportin 1 0.0297 0.0817 0.0817
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0997 0.2903 0.2903
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0047 0.0125
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0139 0.0345 0.0562
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0077 0.016 0.0226
Loa Loa (eye worm) aspartic protease BmAsp-2 0.003 0.0021 0.0021
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0025 0.0066
Echinococcus multilocularis serotonin receptor 0.0553 0.1579 0.1579
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0967 0.2813 0.2813
Echinococcus multilocularis cathepsin L cysteine protease 0.13 0.3808 0.3808
Echinococcus multilocularis peroxidasin 0.0212 0.0564 0.0564
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0035 0.0093
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0061 0.0161
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Brugia malayi hypothetical protein 0.0212 0.0564 0.0564
Brugia malayi MH2 domain containing protein 0.0128 0.0311 0.0311
Plasmodium falciparum serine repeat antigen 6 0.0317 0.0876 0.23
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.013 0.0318 0.0835
Plasmodium falciparum cysteine proteinase falcipain 2b 0.13 0.3808 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0716 0.2065 0.2065
Loa Loa (eye worm) hypothetical protein 0.0179 0.0465 0.0465
Echinococcus granulosus cpg binding protein 0.0034 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0317 0.0876 0.0876
Schistosoma mansoni histone deacetylase 0.0088 0.0191 0.0191
Entamoeba histolytica cysteine proteinase 2 0.0716 0.2065 0.5422
Loa Loa (eye worm) hypothetical protein 0.0074 0.015 0.015
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0058 0.0058
Brugia malayi Ets-domain containing protein 0.007 0.0139 0.0139
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0137 0.0339 0.0339
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0285 0.0779 0.2047
Schistosoma mansoni glycogen phosphorylase 0.0115 0.0274 0.0274
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.13 0.3808 1
Leishmania major cathepsin L-like protease 0.13 0.3808 0.5374
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0914 0.2657 0.2657
Brugia malayi Papain family cysteine protease containing protein 0.0317 0.0876 0.0876
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0061 0.0087
Toxoplasma gondii microneme protein MIC17B 0.003 0.002 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1405 0.412 0.5815
Onchocerca volvulus 0.003 0.002 0.0028
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0058 0.0058
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0716 0.2065 0.2065
Echinococcus multilocularis gamma secretase subunit aph 1 0.0261 0.0708 0.0708
Schistosoma mansoni centrin 0.0155 0.0391 0.0391
Loa Loa (eye worm) papain family cysteine protease containing protein 0.13 0.3808 0.3808
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Echinococcus multilocularis survival motor neuron protein 1 0.0495 0.1405 0.1405
Trypanosoma cruzi calmodulin, putative 0.0155 0.0391 0.0391
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0058 0.0058
Trypanosoma cruzi centrin, putative 0.0158 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0055
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0025 0.0025
Trichomonas vaginalis calmodulin, putative 0.0158 0.0403 0.1057
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0058 0.0151
Trichomonas vaginalis calmodulin, putative 0.0155 0.0391 0.1028
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0183 0.0475 0.0475
Leishmania major calmodulin, putative 0.0155 0.0391 0.0552
Schistosoma mansoni hypothetical protein 0.0101 0.0231 0.0231
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Leishmania major sir2-family protein-like protein 0.0032 0.0025 0.0036
Brugia malayi calpain 5 0.0682 0.1964 0.1964
Loa Loa (eye worm) hypothetical protein 0.0317 0.0876 0.0876
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.0025 0.0068
Schistosoma mansoni importin beta-1 0.0028 0.0013 0.0013
Leishmania major histone deacetylase, putative 0.0098 0.0224 0.0315
Loa Loa (eye worm) hypothetical protein 0.1077 0.3141 0.3141
Onchocerca volvulus 0.003 0.002 0.0028
Echinococcus multilocularis tumor protein p63 0.0376 0.1052 0.1052
Brugia malayi CXXC zinc finger family protein 0.0032 0.0026 0.0026
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0025 0.0036
Plasmodium vivax histone deacetylase, putative 0.0098 0.0224 0.0587
Loa Loa (eye worm) norepinephrine transporter 0.1077 0.3141 0.3141
Mycobacterium tuberculosis Conserved hypothetical protein 0.0289 0.0794 0.1291
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0191 0.0502
Plasmodium vivax SET domain protein, putative 0.01 0.023 0.0604
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0191 0.0191
Echinococcus multilocularis prolyl endopeptidase 0.2399 0.7086 0.7086
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Schistosoma mansoni ap endonuclease 0.004 0.0049 0.0049
Entamoeba histolytica hypothetical protein, conserved 0.0157 0.0399 0.1049
Mycobacterium leprae Probable lipase LipE 0.0039 0.0047 0.0163
Onchocerca volvulus Cathepsin L homolog 0.13 0.3808 0.5374
Schistosoma mansoni hypothetical protein 0.0174 0.0449 0.0449
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0133 0.0327 0.0327
Echinococcus multilocularis beta adrenergic receptor kinase 0.0043 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.01 0.0228 0.0228
Echinococcus granulosus glycogen phosphorylase 0.0115 0.0274 0.0274
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0162 0.0412 0.1083
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Plasmodium vivax proteasome subunit beta type-5, putative 0.0162 0.0412 0.1083
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0025 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0061 0.0161
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0716 0.2065 0.2065
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0183 0.0475 0.0475
Trypanosoma brucei Component of motile flagella 41 0.0155 0.0391 0.0552
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0058 0.0058
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2399 0.7086 0.7086
Echinococcus granulosus Transglutaminase 0.0289 0.0794 0.0794
Schistosoma mansoni neprilysin 0.0026 0.0008 0.0008
Brugia malayi gamma-secretase subunit aph-1 0.0261 0.0708 0.0708
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2731 0.8077 0.8077
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0077 0.016 0.042
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Toxoplasma gondii PAN domain-containing protein 0.003 0.002 0.0028
Echinococcus granulosus histone deacetylase 6 0.0098 0.0224 0.0224
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0315 0.087 0.2285
Loa Loa (eye worm) hypothetical protein 0.01 0.0228 0.0228
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.003 0.0021 0.003
Trypanosoma cruzi Aph-1 protein, putative 0.0102 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0043 0.0058 0.0058
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0055 0.0145
Giardia lamblia Hypothetical protein 0.0157 0.0399 0.108
Schistosoma mansoni calpain (C02 family) 0.0967 0.2813 0.2813
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0315 0.087 0.1228
Echinococcus granulosus calpain 5 0.0967 0.2813 0.2813
Trichomonas vaginalis esterase, putative 0.0039 0.0047 0.0125
Brugia malayi Cathepsin L-like precursor 0.13 0.3808 0.3808
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0315 0.087 0.2285
Toxoplasma gondii ABC1 family protein 0.0039 0.0047 0.0067
Loa Loa (eye worm) hypothetical protein 0.0212 0.0564 0.0564
Schistosoma mansoni caspase-7 (C14 family) 0.0117 0.0279 0.0279
Schistosoma mansoni flap endonuclease-1 0.0025 0.0004 0.0004
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0317 0.0876 0.23
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0317 0.0876 0.23
Schistosoma mansoni histone deacetylase 0.0088 0.0191 0.0191
Echinococcus granulosus proteasome prosome macropain subunit beta 0.005 0.0078 0.0078
Loa Loa (eye worm) prolyl oligopeptidase 0.0315 0.087 0.087
Onchocerca volvulus 0.003 0.002 0.0028
Brugia malayi calpain family protein 1 0.2577 0.7615 0.7615
Echinococcus granulosus calmodulin 0.0155 0.0391 0.0391
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0024 0.0003 0.0003
Loa Loa (eye worm) cathepsin B 0.1263 0.3698 0.3698
Echinococcus granulosus cysteine protease 0.0716 0.2065 0.2065
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0155 0.0391 0.1028
Plasmodium vivax metacaspase 1, putative 0.0044 0.0061 0.0161
Echinococcus multilocularis cathepsin L 0.0716 0.2065 0.2065
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0191 0.0502
Brugia malayi Papain family cysteine protease containing protein 0.0317 0.0876 0.0876
Loa Loa (eye worm) hypothetical protein 0.0317 0.0876 0.0876
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0077 0.016 0.016
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0047 0.0047
Echinococcus multilocularis neurocalcin 0.0155 0.0391 0.0391
Echinococcus granulosus cathepsin L cysteine proteinase 0.13 0.3808 0.3808
Giardia lamblia Alanyl dipeptidyl peptidase 0.0315 0.087 0.2353
Echinococcus multilocularis tissue type plasminogen activator 0.0047 0.0069 0.0069
Brugia malayi PAN domain containing protein 0.003 0.002 0.002
Schistosoma mansoni inhibitor of apoptosis protein 0.0179 0.0465 0.0465
Brugia malayi Trypsin family protein 0.0133 0.0327 0.0327
Plasmodium vivax histone deacetylase, putative 0.0042 0.0056 0.0148
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.003 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.13 0.3808 1
Entamoeba histolytica cysteine protease, putative 0.0716 0.2065 0.5422
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0653 0.1879 0.2651
Entamoeba histolytica hypothetical protein 0.0317 0.0876 0.23
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0012 0.0012
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.002 0.002
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.03 0.03
Toxoplasma gondii PAN domain-containing protein 0.003 0.002 0.0028
Plasmodium vivax unspecified product 0.0399 0.1119 0.2938

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.39 uM Inhibition of IGFR (unknown origin) ChEMBL. 18501599
Ratio IC50 (binding) = 0.48 Ratio of IC50 for IR (unknown origin) to IC50 for IGFR (unknown origin) ChEMBL. 18501599

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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